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Necropsy revealed jaundice, dark-red urine and dark-red discoloration of the kidneys, and a diffusely copper-colored liver with two extensive, firm lesions surrounded by hyperemic halos in the right and left lobes. Histopathological analysis showed multifocal coagulative necrosis in the liver, accompanied by abundant intralesional bacillary structures and multifocal thrombosis. Renal lesions included tubular cell degeneration and necrosis, intracellular hyaline droplet accumulation, and occasional proteinaceous casts within the tubular lumen. PCR and sequencing confirmed the presence of\n                    <jats:italic>Clostridium haemolyticum<\/jats:italic>\n                    DNA in the liver lesions. Based on the characteristic clinical presentation and pathological findings, the diagnosis of bacillary hemoglobinuria was established, with further molecular evidence of the clostridial agent. To our knowledge, this is the first reported case of bacillary hemoglobinuria in the Central-West region of Brazil, and an unusual report in the Tropical Zone in the country, especially in dairy cattle.\n                  <\/jats:p>","DOI":"10.1007\/s11259-026-11537-1","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T07:17:28Z","timestamp":1790407048000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bacillary hemoglobinuria in a dairy cow in Goi\u00e1s State, Central-West Brazil, without demonstrable evidence of active fascioliasis"],"prefix":"10.1007","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9758-5983","authenticated-orcid":false,"given":"Filipe Augusto","family":"Vieira dos Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4763-2000","authenticated-orcid":false,"given":"Isadora David Tavares","family":"de Moraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1606-1708","authenticated-orcid":false,"given":"Tamires Ataides","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8141-4616","authenticated-orcid":false,"given":"Warley Vieira","family":"de Freitas Paula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0607-6992","authenticated-orcid":false,"given":"Carmen Elena","family":"Barragan-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4954-8084","authenticated-orcid":false,"given":"Noenia Sacramento","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3817-225X","authenticated-orcid":false,"given":"Felipe","family":"da Silva Krawczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9023-0007","authenticated-orcid":false,"given":"Mariana Pires","family":"de Campos Telles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-8709","authenticated-orcid":false,"given":"Ana Carolina","family":"Borsanelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7443-275X","authenticated-orcid":false,"given":"Fabiana Marques","family":"Boabaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9392-8574","authenticated-orcid":false,"given":"Luiz Gustavo Schneider","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,26]]},"reference":[{"issue":"2","key":"11537_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1590\/S1984-296120180024","volume":"27","author":"FM Aquino","year":"2018","unstructured":"Aquino FM, Soares VE, Rossi GAM, Nicaretta JE, Bastos TSA, Cruvinel LB, Couto LFM, Cavalcante ASA, Felippelli G, Cruz BC, Maciel WG, Gomes LVC, Lopes WDZ (2018) Prevalence of bovine fascioliasis, areas at risk and ensuing losses in the state of Goi\u00e1s, Brazil. 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Thus, the authors assume full responsibility for the presented data and are available for possible questions, should they be required by the competent authorities. The owner consented the use and publication of information and images as presented in this report.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"599"}}