{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:36:56Z","timestamp":1792820216370,"version":"4.5.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100032844","name":"Ministerul Educa\u0163iei \u015fi Cercet\u0103rii","doi-asserted-by":"publisher","award":["SMIS 2021+ 324771"],"award-info":[{"award-number":["SMIS 2021+ 324771"]}],"id":[{"id":"10.13039\/100032844","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11259-026-11557-x","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:45:08Z","timestamp":1791528308000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of volumetric muscle loss in a dog using bioactive glass\u2013alginate\u2013cellulose composite and a transpositional flap: a case report"],"prefix":"10.1007","volume":"50","author":[{"given":"Alina","family":"Z\u0103voi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Ablassmaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Pop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0218tefana","family":"Mure\u0219an","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrada","family":"Negoescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Lucaci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Purdoiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Feraru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1770-8454","authenticated-orcid":false,"given":"Klara","family":"Magyari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Bel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina","family":"Dragomir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liviu","family":"Oana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Taulescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Dreanc\u0103","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"11557_CR1","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.biomaterials.2015.07.040","volume":"67","author":"A Aurora","year":"2015","unstructured":"Aurora A, Roe JL, Corona BT, Walters TJ (2015) An acellular biologic scaffold does not regenerate appreciable de novo muscle tissue in rat models of volumetric muscle loss injury. Biomaterials 67:393\u2013407. https:\/\/doi.org\/10.1016\/j.biomaterials.2015.07.040","journal-title":"Biomaterials"},{"key":"11557_CR35","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1097\/01.prs.0000221007.97115.1d","volume":"118","author":"JP Beier","year":"2006","unstructured":"Beier JP, Stern-Straeter J, Foerster VT, et al (2006) Tissue Engineering of Injectable Muscle: Three-Dimensional Myoblast-Fibrin Injection in the Syngeneic Rat Animal Model. https:\/\/doi.org\/10.1097\/01.prs.0000221007.97115.1d","journal-title":"Plastic & Reconstructive Surgery"},{"key":"11557_CR2","doi-asserted-by":"publisher","first-page":"2918","DOI":"10.1039\/D3MA00130J","volume":"4","author":"W Chen","year":"2023","unstructured":"Chen W, Chu R, Li H et al (2023) A novel wound dressing based on a gold nanoparticle self-assembled hydrogel to promote wound healing. Mater Adv 4:2918\u20132925. https:\/\/doi.org\/10.1039\/D3MA00130J","journal-title":"Mater Adv"},{"key":"11557_CR3","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1128\/AAC.23.5.766","volume":"23","author":"J Chirife","year":"1983","unstructured":"Chirife J, Herszage L, Joseph A, Kohn ES (1983) In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds. Antimicrob Agents Chemother 23:766\u2013773. https:\/\/doi.org\/10.1128\/AAC.23.5.766","journal-title":"Antimicrob Agents Chemother"},{"key":"11557_CR4","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1634\/stemcells.2006-0372","volume":"25","author":"CA Collins","year":"2007","unstructured":"Collins CA, Zammit PS, Ruiz AP et al (2007) A Population of Myogenic Stem Cells That Survives Skeletal Muscle Aging. Stem Cells 25:885\u2013894. https:\/\/doi.org\/10.1634\/stemcells.2006-0372","journal-title":"Stem Cells"},{"key":"11557_CR5","doi-asserted-by":"publisher","first-page":"C761","DOI":"10.1152\/ajpcell.00189.2013","volume":"305","author":"BT Corona","year":"2013","unstructured":"Corona BT, Garg K, Ward CL et al (2013) Autologous minced muscle grafts: a tissue engineering therapy for the volumetric loss of skeletal muscle. Am J Physiology-Cell Physiol 305:C761\u2013C775. https:\/\/doi.org\/10.1152\/ajpcell.00189.2013","journal-title":"Am J Physiology-Cell Physiol"},{"key":"11557_CR6","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13249","author":"BT Corona","year":"2017","unstructured":"Corona BT, Henderson BEP, Ward CL, Greising SM (2017) Contribution of minced muscle graft progenitor cells to muscle fiber formation after volumetric muscle loss injury in wild-type and immune deficient mice. Physiol Rep. https:\/\/doi.org\/10.14814\/phy2.13249","journal-title":"Physiol Rep"},{"key":"11557_CR7","doi-asserted-by":"publisher","first-page":"148032","DOI":"10.1016\/j.ijbiomac.2025.148032","volume":"330","author":"A Feraru","year":"2025","unstructured":"Feraru A, Z\u0103voi A, Magyari K et al (2025) Skeletal muscle regeneration using bioactive glass-alginate-cellulose composites. Int J Biol Macromol 330:148032. https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.148032","journal-title":"Int J Biol Macromol"},{"key":"11557_CR8","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1038\/nm.3653","volume":"20","author":"SJ Forbes","year":"2014","unstructured":"Forbes SJ, Rosenthal N (2014) Preparing the ground for tissue regeneration: from mechanism to therapy. Nat Med 20:857\u2013869. https:\/\/doi.org\/10.1038\/nm.3653","journal-title":"Nat Med"},{"key":"11557_CR9","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1038\/physci241020a0","volume":"241","author":"G Frens","year":"1973","unstructured":"Frens G (1973) Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions. Nat Phys Sci 241:20\u201322","journal-title":"Nat Phys Sci"},{"key":"11557_CR10","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1007\/s00441-014-2006-6","volume":"358","author":"K Garg","year":"2014","unstructured":"Garg K, Ward CL, Rathbone CR, Corona BT (2014) Transplantation of devitalized muscle scaffolds is insufficient for appreciable de novo muscle fiber regeneration after volumetric muscle loss injury. Cell Tissue Res 358:857\u2013873. https:\/\/doi.org\/10.1007\/s00441-014-2006-6","journal-title":"Cell Tissue Res"},{"key":"11557_CR11","doi-asserted-by":"publisher","first-page":"e0191245","DOI":"10.1371\/journal.pone.0191245","volume":"13","author":"SM Goldman","year":"2018","unstructured":"Goldman SM, Henderson BEP, Walters TJ, Corona BT (2018) Co-delivery of a laminin-111 supplemented hyaluronic acid based hydrogel with minced muscle graft in the treatment of volumetric muscle loss injury. PLoS ONE 13:e0191245. https:\/\/doi.org\/10.1371\/journal.pone.0191245","journal-title":"PLoS ONE"},{"key":"11557_CR12","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.berh.2006.12.004","volume":"21","author":"TAH J\u00e4rvinen","year":"2007","unstructured":"J\u00e4rvinen TAH, J\u00e4rvinen TLN, K\u00e4\u00e4ri\u00e4inen M et al (2007) Muscle injuries: optimising recovery. Best Pract Res Clin Rheumatol 21:317\u2013331. https:\/\/doi.org\/10.1016\/j.berh.2006.12.004","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"11557_CR13","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1038\/nbt1109","volume":"23","author":"S Levenberg","year":"2005","unstructured":"Levenberg S, Rouwkema J, Macdonald M et al (2005) Engineering vascularized skeletal muscle tissue. Nat Biotechnol 23:879\u2013884. https:\/\/doi.org\/10.1038\/nbt1109","journal-title":"Nat Biotechnol"},{"key":"11557_CR14","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.1097\/01.prs.0000260595.85557.41","volume":"119","author":"C-H Lin","year":"2007","unstructured":"Lin C-H, Lin Y-T, Yeh J-T, Chen C-T (2007) Free Functioning Muscle Transfer for Lower Extremity Posttraumatic Composite Structure and Functional Defect. Plast Reconstr Surg 119:2118\u20132126. https:\/\/doi.org\/10.1097\/01.prs.0000260595.85557.41","journal-title":"Plast Reconstr Surg"},{"key":"11557_CR15","doi-asserted-by":"publisher","first-page":"181","DOI":"10.4155\/tde.11.156","volume":"3","author":"Y Liu","year":"2012","unstructured":"Liu Y, Tan J, Thomas A et al (2012) The Shape of Things to Come: Importance of Design in Nanotechnology for Drug Delivery. Ther Deliv 3:181\u2013194. https:\/\/doi.org\/10.4155\/tde.11.156","journal-title":"Ther Deliv"},{"key":"11557_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2017.03.138","author":"K Magyari","year":"2017","unstructured":"Magyari K, Nagy-Simon T, Vulpoi A et al (2017) Novel bioactive glass-AuNP composites for biomedical applications. Mater Sci Eng C Mater Biol Appl. https:\/\/doi.org\/10.1016\/j.msec.2017.03.138","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"11557_CR17","doi-asserted-by":"publisher","first-page":"025011","DOI":"10.1088\/1748-605X\/aafd7d","volume":"14","author":"SM M\u00e2rza","year":"2019","unstructured":"M\u00e2rza SM, Magyari K, Bogdan S et al (2019) Skin wound regeneration with bioactive glass-gold nanoparticles ointment. Biomedical Mater (Bristol) 14:025011. https:\/\/doi.org\/10.1088\/1748-605X\/aafd7d","journal-title":"Biomedical Mater (Bristol)"},{"key":"11557_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26030620","author":"SM M\u00e2rza","year":"2021","unstructured":"M\u00e2rza SM, Magyari K, Bogdan S et al (2021) The impact of composites with silicate-based glasses and gold nanoparticles on skin wound regeneration. Molecules. https:\/\/doi.org\/10.3390\/molecules26030620","journal-title":"Molecules"},{"key":"11557_CR36","doi-asserted-by":"publisher","unstructured":"Mase VJ, Hsu JR, Wolf SE, Wenke JC, Baer DG, Owens J et al (2010) Clinical Application of an Acellular Biologic Scaffold for Surgical Repair of a Large. Trauma Quadriceps Femoris Muscle Defect Orthop 33(7). https:\/\/doi.org\/10.3928\/01477447-20100526-24","DOI":"10.3928\/01477447-20100526-24"},{"key":"11557_CR19","doi-asserted-by":"publisher","first-page":"317","DOI":"10.12968\/jowc.2007.16.7.27053","volume":"16","author":"ANG Mphande","year":"2007","unstructured":"Mphande ANG, Killowe C, Phalira S et al (2007) Effects of honey and sugar dressings on wound healing. J Wound Care 16:317\u2013319. https:\/\/doi.org\/10.12968\/jowc.2007.16.7.27053","journal-title":"J Wound Care"},{"key":"11557_CR20","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.37803","author":"HY Nukaly","year":"2023","unstructured":"Nukaly HY, Ansari SA (2023) An insight into the physicochemical properties of gold nanoparticles in relation to their clinical and diagnostic applications. Cureus. https:\/\/doi.org\/10.7759\/cureus.37803","journal-title":"Cureus"},{"key":"11557_CR21","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1007\/s00776-014-0548-9","volume":"19","author":"S Oshima","year":"2014","unstructured":"Oshima S, Kamei N, Nakasa T et al (2014) Enhancement of muscle repair using human mesenchymal stem cells with a magnetic targeting system in a subchronic muscle injury model. J Orthop Sci 19:478\u2013488. https:\/\/doi.org\/10.1007\/s00776-014-0548-9","journal-title":"J Orthop Sci"},{"key":"11557_CR22","doi-asserted-by":"publisher","first-page":"S73","DOI":"10.1097\/PHM.0000000000000211","volume":"93","author":"C Perez-Terzic","year":"2014","unstructured":"Perez-Terzic C, Childers MK (2014) Regenerative rehabilitation: a new future? Am J Phys Med Rehabil 93:S73\u2013S78. https:\/\/doi.org\/10.1097\/PHM.0000000000000211","journal-title":"Am J Phys Med Rehabil"},{"key":"11557_CR23","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s13287-018-0821-5","volume":"9","author":"X Qiu","year":"2018","unstructured":"Qiu X, Liu S, Zhang H et al (2018) Mesenchymal stem cells and extracellular matrix scaffold promote muscle regeneration by synergistically regulating macrophage polarization toward the M2 phenotype. Stem Cell Res Ther 9:88. https:\/\/doi.org\/10.1186\/s13287-018-0821-5","journal-title":"Stem Cell Res Ther"},{"key":"11557_CR32","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.ajps.2020.10.001","volume":"16","author":"R Ahmad Raus","year":"2021","unstructured":"Raus R, Wan Nawawi WMF, Nasaruddin RR (2021) Alginate and alginate compositesfor biomedical applications. J Pharm Sci 16:280\u2013306 https:\/\/doi.org\/10.1016\/j.ajps.2020.10.001","journal-title":"Asian Journal of Pharmaceutical Sciences"},{"key":"11557_CR30","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1007\/s10570-020-03674-w","volume":"28","author":"H Seddiqi","year":"2021","unstructured":"Seddiqi H, Oliaei E, Honarkar H, et al (2021) Cellulose and its derivatives: towardsbiomedical applications. Cellulose 28:1893\u20131931 https:\/\/doi.org\/10.1007\/s10570-020-03674-w","journal-title":"Cellulose"},{"key":"11557_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.123438","volume":"233","author":"Aleksandra Serafin","year":"2023","unstructured":"Serafin A, Culebras M, Collins MN (2023) Synthesis and evaluation of alginate, gelatin,and hyaluronic acid hybrid hydrogels for tissue engineering applications. Int J Biol Macromol 233:123438 https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.123438","journal-title":"International Journal of Biological Macromolecules"},{"key":"11557_CR24","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1002\/stem.4","volume":"27","author":"M Shi","year":"2009","unstructured":"Shi M, Ishikawa M, Kamei N et al (2009) Acceleration of Skeletal Muscle Regeneration in a Rat Skeletal Muscle Injury Model by Local Injection of Human Peripheral Blood-Derived CD133-Positive Cells. Stem Cells 27:949\u2013960. https:\/\/doi.org\/10.1002\/stem.4","journal-title":"Stem Cells"},{"key":"11557_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2025.100858","volume":"34","author":"Komal Sindhi","year":"2025","unstructured":"Sindhi K, Pingili RB, Beldar V, et al (2025) The role of biomaterials-based scaffolds in advancing skin tissue construct. J Tissue Viability 34:100858 https:\/\/doi.org\/10.1016\/j.jtv.2025.100858","journal-title":"Journal of Tissue Viability"},{"key":"11557_CR25","doi-asserted-by":"publisher","DOI":"10.3390\/ma15051655","author":"ZR T\u00f3th","year":"2022","unstructured":"T\u00f3th ZR, Kiss J, Todea M et al (2022) Bioactive properties of composites based on silicate glasses and different silver and gold structures. Materials (Basel). https:\/\/doi.org\/10.3390\/ma15051655","journal-title":"Materials (Basel)"},{"key":"11557_CR37","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1007\/s00441-011-1185-7","volume":"347","author":"NJ Turner","year":"2012","unstructured":"Turner NJ, Badylak SF (2012) Regeneration of skeletal muscle. Cell Tissue Res 347:759\u2013774 https:\/\/doi.org\/10.1007\/s00441-011-1185-7","journal-title":"Cell and Tissue Research"},{"key":"11557_CR34","doi-asserted-by":"publisher","unstructured":"Williams J (2009) Decision-making in wound closure. In: BSAVA Manual of Canine and Feline Wound Management and Reconstruction. British Small Animal VeterinaryAssociation, pp 25\u201336 https:\/\/doi.org\/10.22233\/9781905319558.3","DOI":"10.22233\/9781905319558.3"},{"key":"11557_CR27","doi-asserted-by":"publisher","DOI":"10.3390\/ma18112529","volume":"18","author":"Alina A Z\u0103voi","year":"2025","unstructured":"Z\u0103voi A-A, Dreanc\u0103 A, Magyari K, et al (2025) Unveiling the Potential of Bioactive Glass in Volumetric Muscle Loss Regeneration. Materials 18:2529.","journal-title":"Materials"},{"key":"11557_CR26","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.1039\/D3MA00682D","volume":"5","author":"W Zhang","year":"2024","unstructured":"Zhang W, Liu L, Cheng H et al (2024) Hydrogel-based dressings designed to facilitate wound healing. Mater Adv 5:1364\u20131394. https:\/\/doi.org\/10.1039\/D3MA00682D","journal-title":"Mater Adv"},{"key":"11557_CR33","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202312964","volume":"37","author":"Y Zhu","year":"2025","unstructured":"Zhu Y, Zhang X, Chang G, et al (2025) Bioactive Glass in Tissue Regeneration:Unveiling Recent Advances in Regenerative Strategies and Applications. Adv.Mater. 37:2312964 https:\/\/doi.org\/10.1002\/adma.202312964","journal-title":"Advanced Materials"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11557-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11557-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11557-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:43:36Z","timestamp":1792817016000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11557-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,9]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["11557"],"URL":"https:\/\/doi.org\/10.1007\/s11259-026-11557-x","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,9]]},"assertion":[{"value":"30 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Written informed consent was obtained from the owner for the participation of their animal in this study.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Klara Magyari, Alexandra Dreanc\u0103, and Marian Tulescu have a patent #CBI 2024\u00a0A 00476 pending to OSIM. Other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"624"}}