{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:39:24Z","timestamp":1792726764095,"version":"4.5.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res Commun"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1007\/s11259-026-11590-w","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:14:49Z","timestamp":1792725289000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Uterine horn echotexture during the first follicular wave after synchronized ovulation and its relationship with antral follicle count in Holstein cows"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4062-7513","authenticated-orcid":false,"given":"Vefa","family":"Tohumcu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9303-6253","authenticated-orcid":false,"given":"Se\u00e7kin","family":"Salar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8332-0514","authenticated-orcid":false,"given":"\u015eifanur","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7912-7703","authenticated-orcid":false,"given":"Alper Yasin","family":"\u00c7iplak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9913-3468","authenticated-orcid":false,"given":"Mehmet","family":"Cengiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-2155","authenticated-orcid":false,"given":"Damla Tu\u011f\u00e7e","family":"Okur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3957-192X","authenticated-orcid":false,"given":"Feride \u0130layda","family":"Uyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,23]]},"reference":[{"key":"11590_CR1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1530\/jrf.0.0940177","volume":"94","author":"GP Adams","year":"1992","unstructured":"Adams GP, Matteri RL, Kastelic JP, Ko JCH, Ginther OJ (1992) Association between surges of follicle-stimulating hormone and the emergence of follicular waves in heifers. J Reprod Fertil 94:177\u2013188. https:\/\/doi.org\/10.1530\/jrf.0.0940177","journal-title":"J Reprod Fertil"},{"key":"11590_CR2","doi-asserted-by":"publisher","first-page":"100678","DOI":"10.1016\/j.animal.2022.100678","volume":"16","author":"JR Bevilaqua","year":"2022","unstructured":"Bevilaqua JR, Rodrigues NN, Rossi GF, Pupin MAF, Silva MO, Borges MS, Fernandes LG, Mercadante MEZ, Monteiro FM, Oliveira MEF (2022) Effect of follicular wave stage on potential fertility predictors and their repeatability coefficient in prepubertal Bos indicus (Nellore) and Bos taurus (Caracu) heifers. Animal 16:100678. https:\/\/doi.org\/10.1016\/j.animal.2022.100678","journal-title":"Animal"},{"key":"11590_CR3","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.theriogenology.2021.12.006","volume":"179","author":"DV Bonato","year":"2022","unstructured":"Bonato DV, Ferreira EB, Gomes DN, Bonato FGC, Droher RG, Morotti F, Seneda MM (2022) Follicular dynamics, luteal characteristics, and progesterone concentrations in synchronized lactating Holstein cows with high and low antral follicle counts. Theriogenology 179:223\u2013229. https:\/\/doi.org\/10.1016\/j.theriogenology.2021.12.006","journal-title":"Theriogenology"},{"key":"11590_CR4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1095\/biolreprod.104.036277","volume":"73","author":"DS Burns","year":"2005","unstructured":"Burns DS, Jimenez-Krassel F, Ireland JLH, Knight PG, Ireland JJ (2005) Numbers of antral follicles during follicular waves in cattle: evidence for high variation among animals, very high repeatability in individuals, and an inverse association with serum follicle-stimulating hormone concentrations. Biol Reprod 73:54\u201362. https:\/\/doi.org\/10.1095\/biolreprod.104.036277","journal-title":"Biol Reprod"},{"key":"11590_CR5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.anireprosci.2014.02.004","volume":"146","author":"M Cengiz","year":"2014","unstructured":"Cengiz M, Kanca H, Salar S, Bastan A, Kucukaslan I, Alkan H, Karakas K, Yuksel O, Hayirli A (2014) Endometrial echotexture parameters in Turkish Saanen goats (Akkeci) during oestrus and early pregnancy. Anim Reprod Sci 146:27\u201333. https:\/\/doi.org\/10.1016\/j.anireprosci.2014.02.004","journal-title":"Anim Reprod Sci"},{"key":"11590_CR6","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/j.theriogenology.2014.06.022","volume":"82","author":"OJ Ginther","year":"2014","unstructured":"Ginther OJ, Siddiqui MAR, Baldrighi JM, Hoffman MM (2014) Effect of intraovarian proximity between dominant follicle and corpus luteum on dimensions and blood flow of each structure in heifers. Theriogenology 82:875\u2013883. https:\/\/doi.org\/10.1016\/j.theriogenology.2014.06.022","journal-title":"Theriogenology"},{"key":"11590_CR7","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.theriogenology.2017.01.018","volume":"92","author":"M Gobikrushanth","year":"2017","unstructured":"Gobikrushanth M, Dutra PA, Bruinj\u00e9 TC, Colazo MG, Butler ST, Ambrose DJ (2017) Repeatability of antral follicle counts and anti-M\u00fcllerian hormone and their associations determined at an unknown stage of follicular growth and an expected day of follicular wave emergence in dairy cows. Theriogenology 92:90\u201394. https:\/\/doi.org\/10.1016\/j.theriogenology.2017.01.018","journal-title":"Theriogenology"},{"key":"11590_CR8","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.anireprosci.2017.07.001","volume":"184","author":"M Hassan","year":"2017","unstructured":"Hassan M, Sattar A, Bilal M, Avais M, Ahmad N (2017) Evaluation of changes in blood flow of the uterine artery by Doppler ultrasonography during the estrous cycle in lactating Bos indicus cows. Anim Reprod Sci 184:78\u201385. https:\/\/doi.org\/10.1016\/j.anireprosci.2017.07.001","journal-title":"Anim Reprod Sci"},{"key":"11590_CR10","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1095\/biolreprod.108.071670","volume":"79","author":"JLH Ireland","year":"2008","unstructured":"Ireland JLH, Scheetz D, Jimenez-Krassel F, Themmen APN, Ward F, Lonergan P, Smith GW, Perez GI, Evans ACO, Ireland JJ (2008) Antral follicle count reliably predicts number of morphologically healthy oocytes and follicles in ovaries of young adult cattle. Biol Reprod 79:1219\u20131225. https:\/\/doi.org\/10.1095\/biolreprod.108.071670","journal-title":"Biol Reprod"},{"key":"11590_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1071\/RD10226","volume":"23","author":"JJ Ireland","year":"2011","unstructured":"Ireland JJ, Smith GW, Scheetz D, Jimenez-Krassel F, Folger JK, Ireland JLH, Mossa F, Lonergan P, Evans ACO (2011) Does size matter in females? An overview of the impact of the high variation in the ovarian reserve on ovarian function and fertility, utility of anti-M\u00fcllerian hormone as a diagnostic marker for fertility and causes of variation in the ovarian reserve in cattle. Reprod Fertil Dev 23:1\u201314. https:\/\/doi.org\/10.1071\/RD10226","journal-title":"Reprod Fertil Dev"},{"key":"11590_CR11","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1095\/biolreprod.108.075093","volume":"80","author":"F Jimenez-Krassel","year":"2009","unstructured":"Jimenez-Krassel F, Folger JK, Ireland JLH, Smith GW, Hou X, Davis JS, Lonergan P, Evans ACO, Ireland JJ (2009) Evidence that high variation in ovarian reserves of healthy young adults has a negative impact on the corpus luteum and endometrium during estrous cycles in cattle. Biol Reprod 80:1272\u20131281. https:\/\/doi.org\/10.1095\/biolreprod.108.075093","journal-title":"Biol Reprod"},{"key":"11590_CR12","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.theriogenology.2015.04.033","volume":"84","author":"H Karamishabankareh","year":"2015","unstructured":"Karamishabankareh H, Hajarian H, Shahsavari MH, Moradinejad R (2015) In vivo and in vitro study of the function of the left and right bovine ovaries. Theriogenology 84:724\u2013731. https:\/\/doi.org\/10.1016\/j.theriogenology.2015.04.033","journal-title":"Theriogenology"},{"key":"11590_CR13","doi-asserted-by":"publisher","first-page":"343","DOI":"10.15653\/TPG-140473","volume":"42","author":"\u0130 K\u00fc\u00e7\u00fckaslan","year":"2014","unstructured":"K\u00fc\u00e7\u00fckaslan \u0130, Kaya D, Emre B, Bollwein H, \u00d6zyurtlu N, M\u00fclaz\u0131mo\u011flu SB, Aslan S (2014) Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis. Tierarztl Prax Ausg G Grosstiere Nutztiere 42:343\u2013350. https:\/\/doi.org\/10.15653\/TPG-140473","journal-title":"Tierarztl Prax Ausg G Grosstiere Nutztiere"},{"key":"11590_CR14","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.theriogenology.2015.09.026","volume":"85","author":"MF Martinez","year":"2016","unstructured":"Martinez MF, Sanderson N, Quirke LD, Lawrence SB, Juengel JL (2016) Association between antral follicle count and reproductive measures in New Zealand lactating dairy cows maintained in a pasture-based production system. Theriogenology 85:466\u2013475. https:\/\/doi.org\/10.1016\/j.theriogenology.2015.09.026","journal-title":"Theriogenology"},{"key":"11590_CR15","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.3390\/ani15152253","volume":"15","author":"R Miura","year":"2025","unstructured":"Miura R, Matsui M (2025) Factors associated with the occurrence of the first-follicular-wave dominant follicle on the ovary ipsilateral to the corpus luteum in dairy cattle. Animals 15:2253. https:\/\/doi.org\/10.3390\/ani15152253","journal-title":"Animals"},{"key":"11590_CR16","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1095\/biolreprod.113.117077","volume":"90","author":"D Monniaux","year":"2014","unstructured":"Monniaux D, Cl\u00e9ment F, Dalbi\u00e8s-Tran R, Estienne A, Fabre S, Mansanet C, Monget P (2014) The ovarian reserve of primordial follicles and the dynamic reserve of antral growing follicles: what is the link? Biol Reprod 90:85. https:\/\/doi.org\/10.1095\/biolreprod.113.117077","journal-title":"Biol Reprod"},{"key":"11590_CR17","doi-asserted-by":"publisher","first-page":"100744","DOI":"10.1016\/j.animal.2023.100744","volume":"17","author":"F Mossa","year":"2023","unstructured":"Mossa F, Evans ACO (2023) Review: the ovarian follicular reserve \u2014 implications for fertility in ruminants. Animal 17:100744. https:\/\/doi.org\/10.1016\/j.animal.2023.100744","journal-title":"Animal"},{"key":"11590_CR18","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.3168\/jds.2011-4325","volume":"95","author":"F Mossa","year":"2012","unstructured":"Mossa F, Walsh SW, Butler ST, Berry DP, Carter F, Lonergan P, Smith GW, Ireland JJ, Evans ACO (2012) Low numbers of ovarian follicles\u2009\u2265\u20093\u00a0mm in diameter are associated with low fertility in dairy cows. J Dairy Sci 95:2355\u20132361. https:\/\/doi.org\/10.3168\/jds.2011-4325","journal-title":"J Dairy Sci"},{"key":"11590_CR19","doi-asserted-by":"publisher","DOI":"10.17226\/25806","volume-title":"Nutrient requirements of dairy cattle, 8th rev edn","author":"National Academies of Sciences, Engineering, and Medicine (NASEM)","year":"2021","unstructured":"National Academies of Sciences, Engineering, and Medicine (NASEM) (2021) Nutrient requirements of dairy cattle, 8th rev edn. National Academies, Washington, DC. https:\/\/doi.org\/10.17226\/25806"},{"key":"11590_CR20","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/0093-691X(93)90004-O","volume":"39","author":"S Ohtani","year":"1993","unstructured":"Ohtani S, Okuda K, Nishimura K, Mohri S (1993) Histological changes in bovine endometrium during the estrous cycle. Theriogenology 39:1033\u20131042. https:\/\/doi.org\/10.1016\/0093-691X(93)90004-O","journal-title":"Theriogenology"},{"key":"11590_CR21","doi-asserted-by":"publisher","first-page":"e3000410","DOI":"10.1371\/journal.pbio.3000410","volume":"18","author":"N Percie du Sert","year":"2020","unstructured":"Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, W\u00fcrbel H (2020) The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. PLoS Biol 18:e3000410. https:\/\/doi.org\/10.1371\/journal.pbio.3000410","journal-title":"PLoS Biol"},{"key":"11590_CR22","unstructured":"Pinheiro J, Bates D (2024) nlme: linear and nonlinear mixed effects models. R package version 3.1\u2013168. https:\/\/CRAN.R-project.org\/package=nlme"},{"key":"11590_CR23","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.anireprosci.2015.01.015","volume":"155","author":"B Polat","year":"2015","unstructured":"Polat B, Cengiz M, Cannazik O, Colak A, Oruc E, Altun S, Salar S, Bastan A (2015) Endometrial echotexture variables in postpartum cows with subclinical endometritis. Anim Reprod Sci 155:50\u201355. https:\/\/doi.org\/10.1016\/j.anireprosci.2015.01.015","journal-title":"Anim Reprod Sci"},{"key":"11590_CR24","volume-title":"RStudio: integrated development environment for R. Posit Software","author":"Posit Team","year":"2026","unstructured":"Posit Team (2026) RStudio: integrated development environment for R. Posit Software. PBC, Boston. https:\/\/posit.co"},{"key":"11590_CR25","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/0093-691X(95)00279-H","volume":"44","author":"JR Pursley","year":"1995","unstructured":"Pursley JR, Mee MO, Wiltbank MC (1995) Synchronization of ovulation in dairy cows using PGF2\u03b1 and GnRH. Theriogenology 44:915\u2013923. https:\/\/doi.org\/10.1016\/0093-691X(95)00279-H","journal-title":"Theriogenology"},{"key":"11590_CR26","volume-title":"R: a language and environment for statistical computing, version 4.3.2","author":"R Core Team","year":"2023","unstructured":"R Core Team (2023) R: a language and environment for statistical computing, version 4.3.2. R foundation for statistical computing, Vienna. https:\/\/www.R-project.org\/"},{"key":"11590_CR27","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.theriogenology.2022.10.036","volume":"195","author":"I Rajesh","year":"2023","unstructured":"Rajesh I, Colazo MG, Gobikrushanth M, Carrelli JE, Oba M, Ambrose DJ (2023) Superovulatory response, anti-M\u00fcllerian hormone concentration and antral follicle count in Holstein cattle with short or long anogenital distance. Theriogenology 195:249\u2013256. https:\/\/doi.org\/10.1016\/j.theriogenology.2022.10.036","journal-title":"Theriogenology"},{"key":"11590_CR28","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1095\/biolreprod.108.072157","volume":"80","author":"C Rico","year":"2009","unstructured":"Rico C, Fabre S, M\u00e9digue C, di Clemente N, Cl\u00e9ment F, Bontoux M, Touz\u00e9 J-L, Dupont M, Briant E, R\u00e9my B, Beckers J-F, Monniaux D (2009) Anti-M\u00fcllerian hormone is an endocrine marker of ovarian gonadotropin-responsive follicles and can help to predict superovulatory responses in the cow. Biol Reprod 80:50\u201359. https:\/\/doi.org\/10.1095\/biolreprod.108.072157","journal-title":"Biol Reprod"},{"key":"11590_CR29","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/s12958-019-0534-3","volume":"17","author":"K Sakaguchi","year":"2019","unstructured":"Sakaguchi K, Yanagawa Y, Yoshioka K, Suda T, Katagiri S, Nagano M (2019) Relationships between the antral follicle count, steroidogenesis, and secretion of follicle-stimulating hormone and anti-M\u00fcllerian hormone during follicular growth in cattle. Reprod Biol Endocrinol 17:88. https:\/\/doi.org\/10.1186\/s12958-019-0534-3","journal-title":"Reprod Biol Endocrinol"},{"key":"11590_CR30","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.anireprosci.2007.12.022","volume":"106","author":"S Schmauder","year":"2008","unstructured":"Schmauder S, Weber F, Kiossis E, Bollwein H (2008) Cyclic changes in endometrial echotexture of cows using a computer-assisted program for the analysis of first- and second-order grey level statistics of B-mode ultrasound images. Anim Reprod Sci 106:153\u2013161. https:\/\/doi.org\/10.1016\/j.anireprosci.2007.12.022","journal-title":"Anim Reprod Sci"},{"key":"11590_CR31","doi-asserted-by":"publisher","first-page":"107291","DOI":"10.1016\/j.anireprosci.2023.107291","volume":"255","author":"L Schwarzmann","year":"2023","unstructured":"Schwarzmann L, Marchand A, Knutti B, Bruckmaier R, Bollwein H, Scarlet D (2023) Effects of postpartum diseases on antral follicle count and serum concentration of anti-M\u00fcllerian hormone in dairy cows. Anim Reprod Sci 255:107291. https:\/\/doi.org\/10.1016\/j.anireprosci.2023.107291","journal-title":"Anim Reprod Sci"},{"key":"11590_CR32","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1530\/REP-06-0133","volume":"134","author":"CK Wang","year":"2007","unstructured":"Wang CK, Robinson RS, Flint APF, Mann GE (2007) Quantitative analysis of changes in endometrial gland morphology during the bovine oestrous cycle and their association with progesterone levels. Reproduction 134:365\u2013371. https:\/\/doi.org\/10.1530\/REP-06-0133","journal-title":"Reproduction"}],"container-title":["Veterinary Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11590-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11590-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11259-026-11590-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:14:58Z","timestamp":1792725298000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11259-026-11590-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,23]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,1]]}},"alternative-id":["11590"],"URL":"https:\/\/doi.org\/10.1007\/s11259-026-11590-w","relation":{},"ISSN":["0165-7380","1573-7446"],"issn-type":[{"value":"0165-7380","type":"print"},{"value":"1573-7446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,23]]},"assertion":[{"value":"12 August 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All animal procedures were approved by the Local Animal Care and Use Ethics Committee of the Experimental Animals Application and Research Center, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University (MUDEM-HADYEK; approval no. 09\/24, 17 May 2024). Written informed consent was obtained from the herd owner.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable; the study did not involve human participants.","order":2,"name":"Ethics","label":"Consent to participate\/Consent to publish","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"12"}}