{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:03:51Z","timestamp":1771661031473,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T00:00:00Z","timestamp":1242345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virus Genes"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1007\/s11262-009-0365-y","type":"journal-article","created":{"date-parts":[[2009,5,14]],"date-time":"2009-05-14T04:32:48Z","timestamp":1242275568000},"page":"76-80","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Infection and replication of avian influenza H5N1 virus in an infected human"],"prefix":"10.1007","volume":"39","author":[{"given":"Jing-Jiao","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan-Yun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Mei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Jun","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Fang","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,5,15]]},"reference":[{"key":"365_CR1","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1126\/science.1115273","volume":"309","author":"J Liu","year":"2005","unstructured":"J. Liu, H. Xiao, F. Lei, Q. Zhu, K. Qin, X.W. Zhang, X.L. Zhang, D. Zhao, G. Wang, Y. Feng, J. Ma, W. Liu, J. Wang, G.F. Gao, Science 309, 1206 (2005). doi:https:\/\/doi.org\/10.1126\/science.1115273","journal-title":"Science"},{"key":"365_CR2","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1354\/vp.44-2-137","volume":"44","author":"JP Teifke","year":"2007","unstructured":"J.P. Teifke, R. Klopfleisch, A. Globig, E. Starick, B. Hoffmann, P.U. Wolf, M. Beer, T.C. Mettenleiter, T.C. Harder, Vet. Pathol. 44, 137\u2013143 (2007). doi:https:\/\/doi.org\/10.1354\/vp.44-2-137","journal-title":"Vet. Pathol."},{"key":"365_CR3","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.3201\/eid1411.080557","volume":"14","author":"CO Aiki-Raji","year":"2008","unstructured":"C.O. Aiki-Raji, P.V. Aguilar, Y.K. Kwon, S. Goetz, D.L. Suarez, A.I. Jethra, O. Nash, C.A. Adeyefa, F.D. Adu, D. Swayne, C.F. Basler, Emerg. Infect. Dis. 14, 1753\u20131755 (2008). doi:https:\/\/doi.org\/10.3201\/eid1411.080557","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR4","doi-asserted-by":"publisher","first-page":"10452","DOI":"10.1073\/pnas.0403212101","volume":"101","author":"H Chen","year":"2004","unstructured":"H. Chen, G. Deng, Z. Li, G. Tian, Y. Li, P. Jiao, L. Zhang, Z. Liu, R.G. Webster, K. Yu, Proc. Natl. Acad. Sci. USA 101, 10452\u201310457 (2004). doi:https:\/\/doi.org\/10.1073\/pnas.0403212101","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"365_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0378-1135(03)00132-9","volume":"95","author":"H Tanaka","year":"2003","unstructured":"H. Tanaka, C.H. Park, A. Ninomiya, H. Ozaki, A. Takada, T. Umemura, H. Kida, Vet. Microbiol. 95, 1\u201313 (2003). doi:https:\/\/doi.org\/10.1016\/S0378-1135(03)00132-9","journal-title":"Vet. Microbiol."},{"key":"365_CR6","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1007\/s00705-001-0750-x","volume":"147","author":"CH Park","year":"2002","unstructured":"C.H. Park, M. Ishinaka, A. Takada, H. Kida, T. Kimura, K. Ochiai, T. Umemura, Arch. Virol. 147, 1425\u20131436 (2002). doi:https:\/\/doi.org\/10.1007\/s00705-001-0750-x","journal-title":"Arch. Virol."},{"key":"365_CR7","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.3201\/eid1012.040759","volume":"10","author":"J Keawcharoen","year":"2004","unstructured":"J. Keawcharoen, K. Oraveerakul, T. Kuiken, R.A. Fouchier, A. Amonsin, S. Payungporn, S. Noppornpanth, S. Wattanodorn, A. Theambooniers, R. Tantilertcharoen, R. Pattanarangsan, N. Arya, P. Ratanakorn, D.M. Osterhaus, Y. Poovorawan, Emerg. Infect. Dis. 10, 2189\u20132191 (2004)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR8","doi-asserted-by":"publisher","first-page":"11788","DOI":"10.1128\/JVI.79.18.11788-11800.2005","volume":"79","author":"TR Maines","year":"2005","unstructured":"T.R. Maines, X.H. Lu, S.M. Erb, L. Edwards, J. Guarner, P.W. Greer, D.C. Nguyen, K.J. Szretter, L.M. Chen, P. Thawatsupha, M. Chittaganpitch, S. Waicharoen, D.T. Nguyen, T. Nguyen, H.H. Nguyen, J.H. Kim, L.T. Hoang, C. Kang, L.S. Phuong, W. Lim, S. Zaki, R.O. Donis, N.J. Cox, J.M. Katz, T.M. Tumpey, J. Virol. 79, 11788\u201311800 (2005). doi:https:\/\/doi.org\/10.1128\/JVI.79.18.11788-11800.2005","journal-title":"J. Virol."},{"key":"365_CR9","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1128\/JVI.79.4.2191-2198.2005","volume":"79","author":"EA Govorkova","year":"2005","unstructured":"E.A. Govorkova, J.E. Rehg, S. Krauss, H.L. Yen, Y. Guan, M. Peiris, T.D. Nguyen, T.H. Hanh, P. Puthavathana, H.T. Long, C. Buranathai, W. Lim, R.G. Webster, E. Hoffmann, J. Virol. 79, 2191\u20132198 (2005)","journal-title":"J. Virol."},{"key":"365_CR10","doi-asserted-by":"publisher","first-page":"5976","DOI":"10.1128\/JVI.00110-06","volume":"80","author":"HL Chen","year":"2006","unstructured":"H.L. Chen, Y.B. Li, Z.J. Li, J.Z. Shi, K. Shinya, G.H. Deng, Q.L. Qi, G.B. Tian, S.F. Fan, H.D. Zhao, Y.X. Sun, Y. Kawaoka, J. Virol. 80, 5976\u20135983 (2006). doi:https:\/\/doi.org\/10.1128\/JVI.00110-06","journal-title":"J. Virol."},{"key":"365_CR11","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/S0140-6736(04)15595-5","volume":"363","author":"JS Peiris","year":"2004","unstructured":"J.S. Peiris, W.C. Yu, C.W. Leung, C.Y. Cheung, W.F. Ng, J.M. Nicholls, T.K. Ng, K.H. Chan, S.T. Lai, W.L. Lim, K.Y. Yuen, Y. Guan, Lancet 363, 617\u2013619 (2004). doi:https:\/\/doi.org\/10.1016\/S0140-6736(04)15595-5","journal-title":"Lancet"},{"key":"365_CR12","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1002\/1096-9071(200103)63:3<242::AID-JMV1007>3.0.CO;2-N","volume":"63","author":"KF To","year":"2001","unstructured":"K.F. To, P.K. Chan, K.F. Chan, W.K. Lee, W.Y. Lam, K.F. Wong, N.L. Tang, D.N. Tsang, R.Y. Sung, T.A. Buckley, J.S. Tam, A.F. Cheng, J. Med. Virol. 63, 242\u2013246 (2001). doi:https:\/\/doi.org\/10.1002\/1096-9071(200103)63:3<242::AID-JMV1007>3.0.CO;2-N","journal-title":"J. Med. Virol."},{"key":"365_CR13","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.3201\/eid1206.060227","volume":"12","author":"S Chutinimitkul","year":"2006","unstructured":"S. Chutinimitkul, P. Bhattarakosol, S. Srisuratanon, A. Eiamudomkan, K. Kongsomboon, S. Damrongwatanapokin, A. Chaisingh, K. Suwannakarn, T. Chieochansin, A. Theamboonlers, Y. Poovorawan, Emerg. Infect. Dis. 12, 1041\u20131043 (2006)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR14","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1056\/NEJMra052211","volume":"353","author":"JH Beigel","year":"2005","unstructured":"J.H. Beigel, J. Farrar, A.M. Han, F.G. Hayden, R. Hyer, M.D. de Jong, S. Lochindarat, T.K. Nguyen, T.H. Nguyen, T.H. Tran, A. Nicoll, S. Touch, K.Y. Yuen, N. Engl. J. Med. 353, 1374\u20131385 (2005). doi:https:\/\/doi.org\/10.1056\/NEJMra052211","journal-title":"N. Engl. J. Med."},{"key":"365_CR15","doi-asserted-by":"publisher","first-page":"708","DOI":"10.3201\/eid1305.060572","volume":"13","author":"M Uiprasertkul","year":"2007","unstructured":"M. Uiprasertkul, R. Kitphati, P. Puthavathana, R. Kriwong, A. Kongchanagul, K. Ungchusak, S. Angkasekwinai, K. Chokephaibulkit, K. Srisook, N. Vanprapar, P. Auewarakul, Emerg. Infect. Dis. 13, 708\u2013712 (2007)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR16","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1038\/nm1477","volume":"17","author":"MD de Jong","year":"2006","unstructured":"M.D. de Jong, C.P. Simmons, T.T. Thanh, V.M. Hien, G.J. Smith, T.N. Chau, D.M. Hoang, N.V. Chau, T.H. Khanh, V.C. Dong, P.T. Qui, B.V. Cam, Q. Ha do, Y. Guan, J.S. Peiris, N.T. Chinh, T.T. Hien, J. Farrar, Nat. Med. 17, 1203\u20131207 (2006). doi:https:\/\/doi.org\/10.1038\/nm1477","journal-title":"Nat. Med."},{"key":"365_CR17","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1056\/NEJMra0707279","volume":"358","author":"AN Abdel-Ghafar","year":"2008","unstructured":"A.N. Abdel-Ghafar, T. Chotpitayasunondh, Z. Gao, F.G. Hayden, D.H. Nguyen, M.D. de Jong, A. Naghdaliyev, J.S. Peiris, N. Shindo, S. Soeroso, T.M. Uyeki, N. Engl. J. Med. 358, 261\u2013273 (2008). doi:https:\/\/doi.org\/10.1056\/NEJMra0707279","journal-title":"N. Engl. J. Med."},{"key":"365_CR18","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/440435a","volume":"440","author":"K Shinya","year":"2006","unstructured":"K. Shinya, M. Ebina, S. Yamada, M. Ono, N. Kasai, Y. Kawaoka, Nature 440, 435\u2013436 (2006). doi:https:\/\/doi.org\/10.1038\/440435a","journal-title":"Nature"},{"key":"365_CR19","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1126\/science.1125548","volume":"312","author":"D van Riel","year":"2006","unstructured":"D. van Riel, V.J. Munster, E. de Wit, G.F. Rimmelzwaan, R.A. Fouchier, A.D. Osterhaus, T. Kuiken, Science 312, 399 (2006). doi:https:\/\/doi.org\/10.1126\/science.1125548","journal-title":"Science"},{"key":"365_CR20","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.2353\/ajpath.2007.070248","volume":"171","author":"D van Riel","year":"2007","unstructured":"D. van Riel, V.J. Munster, E. de Wit, G.F. Rimmelzwaan, R.A. Fouchier, A.D. Osterhaus, T. Kuiken, Am. J. Pathol. 171, 1215\u20131223 (2007)","journal-title":"Am. J. Pathol."},{"key":"365_CR21","first-page":"126","volume":"23","author":"HL Jing","year":"2008","unstructured":"H.L. Jing, J.D. Cheng, J.M. Zhang, Chin. J. Forensic Med. 23, 126\u2013127 (2008)","journal-title":"Chin. J. Forensic Med."},{"key":"365_CR22","doi-asserted-by":"publisher","first-page":"6105","DOI":"10.1128\/JVI.74.13.6105-6116.2000","volume":"74","author":"TM Tumpey","year":"2000","unstructured":"T.M. Tumpey, X. Lu, T. Morken, S.R. Zaki, J.M. Katz, J. Virol. 74, 6105\u20136116 (2000). doi:https:\/\/doi.org\/10.1128\/JVI.74.13.6105-6116.2000","journal-title":"J. Virol."},{"key":"365_CR23","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1080\/03079450600714510","volume":"35","author":"C Antarasena","year":"2006","unstructured":"C. Antarasena, R. Sirimujalin, P. Prommuang, S.D. Blacksell, N. Promkuntod, P. Prommuang, Avian Pathol. 35, 250\u2013253 (2006). doi:https:\/\/doi.org\/10.1080\/03079450600714510","journal-title":"Avian Pathol."},{"key":"365_CR24","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.3201\/eid1107.041313","volume":"11","author":"M Uiprasertkul","year":"2005","unstructured":"M. Uiprasertkul, P. Puthavathana, K. Sangsiriwut, P. Pooruk, K. Srisook, M. Peiris, J.M. Nicholls, K. Chokephaibulkit, N. Vanprapar, P. Auewarakul, Emerg. Infect. Dis. 11, 1036\u20131041 (2005)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR25","doi-asserted-by":"publisher","first-page":"11705","DOI":"10.1128\/JVI.79.18.11705-11715.2005","volume":"79","author":"T Suzuki","year":"2005","unstructured":"T. Suzuki, T. Takahashi, C.T. Guo, K.I. Hidari, D. Miyamoto, H. Goto, Y. Kawaoka, Y. Suzuki, J. Virol. 79, 11705\u201311715 (2005). doi:https:\/\/doi.org\/10.1128\/JVI.79.18.11705-11715.2005","journal-title":"J. Virol."},{"key":"365_CR26","doi-asserted-by":"publisher","first-page":"881","DOI":"10.3201\/eid1206.051336","volume":"12","author":"G Neumann","year":"2006","unstructured":"G. Neumann, Y. Kawaoka, Emerg. Infect. Dis. 12, 881\u2013886 (2006)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR27","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3201\/eid1007.040415","volume":"10","author":"A Apisarnthanarak","year":"2004","unstructured":"A. Apisarnthanarak, R. Kitphati, K. Thongphubeth, P. Patoomanunt, P. Anthanont, W. Auwanit, P. Thawatsupha, M. Chittaganpitch, S. Saeng-Aroon, S. Waicharoen, P. Apisarnthanarak, G.A. Storch, L.M. Mundy, V.J. Fraser, Emerg. Infect. Dis. 10, 1321\u20131324 (2004)","journal-title":"Emerg. Infect. Dis."},{"key":"365_CR28","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.jcv.2007.04.010","volume":"39","author":"P Buchy","year":"2007","unstructured":"P. Buchy, S. Mardy, S. Vong, T. Toyoda, J.T. Aubin, M. Miller, S. Touch, L. Sovann, J.B. Dufourcq, B. Richner, P.V. Tu, N.T. Tien, W. Lim, J.S. Peiris, W.S. Vander, J. Clin. Virol. 39, 164\u2013168 (2007). doi:https:\/\/doi.org\/10.1016\/j.jcv.2007.04.010","journal-title":"J. Clin. Virol."},{"key":"365_CR29","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1016\/S0140-6736(07)61515-3","volume":"370","author":"J Gu","year":"2008","unstructured":"J. Gu, Z. Xie, Z. Gao, J. Liu, C. Korteweg, J. Ye, L.T. Lau, J. Lu, Z. Gao, B. Zhang, M.A. McNutt, M. Lu, V.M. Anderson, E. Gong, A.C. Yu, W.I. Lipkin, Lancet 370, 1137\u20131145 (2008). doi:https:\/\/doi.org\/10.1016\/S0140-6736(07)61515-3","journal-title":"Lancet"},{"key":"365_CR30","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1128\/CMR.14.1.129-149.2001","volume":"14","author":"T Horimoto","year":"2001","unstructured":"T. Horimoto, Y. Kawaoka, Clin. Microbiol. Rev. 14, 129\u2013149 (2001). doi:https:\/\/doi.org\/10.1128\/CMR.14.1.129-149.2001","journal-title":"Clin. Microbiol. Rev."},{"key":"365_CR31","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1016\/S0140-6736(08)60627-3","volume":"371","author":"A Gambotto","year":"2007","unstructured":"A. Gambotto, S.M. Barratt-Boyes, M.D. de Jong, G. Neumann, Y. Kawaoka, Lancet 371, 1464\u20131475 (2007). doi:https:\/\/doi.org\/10.1016\/S0140-6736(08)60627-3","journal-title":"Lancet"},{"key":"365_CR32","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1056\/NEJMoa044307","volume":"352","author":"MD de Jong","year":"2005","unstructured":"M.D. de Jong, V.C. Bach, T.Q. Phan, M.H. Vo, T.T. Tran, B.H. Nguyen, M. Beld, T.P. Le, H.K. Truong, V.V. Nguyen, T.H. Tran, Q.H. Do, J. Farrar, N. Engl. J. Med. 352, 686\u2013691 (2005). doi:https:\/\/doi.org\/10.1056\/NEJMoa044307","journal-title":"N. Engl. J. Med."},{"key":"365_CR33","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1007\/s00705-007-0985-2","volume":"152","author":"JJ Zhou","year":"2007","unstructured":"J.J. Zhou, J. Fu, D.Y. Fang, H.J. Yan, J. Tian, J.M. Zhou, J.P. Tao, Y. Liang, L.F. Jiang, Arch. Virol. 152, 1515\u20131521 (2007). doi:https:\/\/doi.org\/10.1007\/s00705-007-0985-2","journal-title":"Arch. Virol."}],"container-title":["Virus Genes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-009-0365-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11262-009-0365-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-009-0365-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-009-0365-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:22:45Z","timestamp":1744161765000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11262-009-0365-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,15]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["365"],"URL":"https:\/\/doi.org\/10.1007\/s11262-009-0365-y","relation":{},"ISSN":["0920-8569","1572-994X"],"issn-type":[{"value":"0920-8569","type":"print"},{"value":"1572-994X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,15]]},"assertion":[{"value":"27 December 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}