{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:49:39Z","timestamp":1760708979384,"version":"3.37.3"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T00:00:00Z","timestamp":1452038400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001700","name":"the Ministry of Education, Culture, Sports, Science and Technology of Japan","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virus Genes"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s11262-015-1277-7","type":"journal-article","created":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T15:31:17Z","timestamp":1452094277000},"page":"4-13","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52\/p100 and RelB"],"prefix":"10.1007","volume":"52","author":[{"given":"Yosuke","family":"Motai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Takachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshifumi","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Mizuguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Aoyagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuji","family":"Terai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuetsu","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,1,6]]},"reference":[{"issue":"10","key":"1277_CR1","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/S0929-6646(10)60112-X","volume":"109","author":"KT Jeang","year":"2010","unstructured":"K.T. Jeang, HTLV-1 and adult T-cell leukemia: insights into viral transformation of cells 30\u00a0years after virus discovery. J. Formos. Med. Assoc. 109(10), 688\u2013693 (2010)","journal-title":"J. Formos. Med. Assoc."},{"issue":"5","key":"1277_CR2","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s12185-011-0937-1","volume":"94","author":"J Yasunaga","year":"2011","unstructured":"J. Yasunaga, M. Matsuoka, Molecular mechanisms of HTLV-1 infection and pathogenesis. Int. J. Hematol. 94(5), 435\u2013442 (2011)","journal-title":"Int. J. Hematol."},{"issue":"39","key":"1277_CR3","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1038\/sj.onc.1208975","volume":"24","author":"WW Hall","year":"2005","unstructured":"W.W. Hall, M. Fujii, Deregulation of cell-signaling pathways in HTLV-1 infection. Oncogene 24(39), 5965\u20135975 (2005)","journal-title":"Oncogene"},{"issue":"117","key":"1277_CR4","first-page":"1742","volume":"6","author":"M Higuchi","year":"2009","unstructured":"M. Higuchi, M. Fujii, Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis. Retrovirology 6(117), 1742\u20131746 (2009)","journal-title":"Retrovirology"},{"key":"1277_CR5","author":"V Ciminale","year":"2014","unstructured":"V. Ciminale, F. Rende, U. Bertazzoni, M.G. Romanelli, HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties. Front Microbiol (2014). doi: 10.3389\/fmicb.2014.00398","journal-title":"Front Microbiol"},{"issue":"3","key":"1277_CR6","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/JVI.67.3.1211-1217.1993","volume":"67","author":"T Akagi","year":"1993","unstructured":"T. Akagi, K. Shimotohno, Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathway. J. Virol. 67(3), 1211\u20131217 (1993)","journal-title":"J. Virol."},{"issue":"7","key":"1277_CR7","doi-asserted-by":"crossref","first-page":"4570","DOI":"10.1128\/JVI.66.7.4570-4575.1992","volume":"66","author":"R Grassmann","year":"1992","unstructured":"R. Grassmann, S. Berchtold, I. Radant, M. Alt, B. Fleckenstein, J.G. Sodroski, W.A. Haseltine, U. Ramstedt, Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture. J. Virol. 66(7), 4570\u20134575 (1992)","journal-title":"J. Virol."},{"issue":"5","key":"1277_CR8","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/nm0507-527","volume":"13","author":"T Ohsugi","year":"2007","unstructured":"T. Ohsugi, T. Kumasaka, S. Okada, T. Urano, The Tax protein of HTLV-1 promotes oncogenesis in not only immature T cells but also mature T cells. Nat. Med. 13(5), 527\u2013528 (2007)","journal-title":"Nat. Med."},{"issue":"4","key":"1277_CR9","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/nm1389","volume":"12","author":"H Hasegawa","year":"2006","unstructured":"H. Hasegawa, H. Sawa, M.J. Lewis, Y. Orba, N. Sheehy, Y. Yamamoto, T. Ichinohe, Y. Tsunetsugu-Yokota, H. Katano, H. Takahashi, J. Matsuda, T. Sata, T. Kurata, K. Nagashima, W.W. Hall, Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. Nat. Med. 12(4), 466\u2013472 (2006)","journal-title":"Nat. Med."},{"issue":"6","key":"1277_CR10","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1128\/JVI.71.6.4445-4451.1997","volume":"71","author":"K Matsumoto","year":"1997","unstructured":"K. Matsumoto, H. Shibata, J.I. Fujisawa, H. Inoue, A. Hakura, T. Tsukahara, M. Fujii, Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways. J. Virol. 71(6), 4445\u20134451 (1997)","journal-title":"J. Virol."},{"issue":"4","key":"1277_CR11","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1002\/j.1460-2075.1996.tb00422.x","volume":"15","author":"S Yamaoka","year":"1996","unstructured":"S. Yamaoka, H. Inoue, M. Sakurai, T. Sugiyama, M. Hazama, T. Yamada, M. Hatanaka, Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J. 15(4), 873\u2013887 (1996)","journal-title":"EMBO J."},{"issue":"6","key":"1277_CR12","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3390\/v3060714","volume":"3","author":"Z Qu","year":"2011","unstructured":"Z. Qu, G. Xiao, Human T-cell lymphotropic virus: a model of NF-kappaB-associated tumorigenesis. Viruses 3(6), 714\u2013749 (2011)","journal-title":"Viruses"},{"issue":"3","key":"1277_CR13","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1182\/blood-2003-11-3967","volume":"104","author":"S Mitra-Kaushik","year":"2004","unstructured":"S. Mitra-Kaushik, J.C. Harding, J.L. Hess, L. Ratner, Effects of the proteasome inhibitor PS-341 on tumor growth in HTLV-1 Tax transgenic mice and Tax tumor transplants. Blood 104(3), 802\u2013809 (2004)","journal-title":"Blood"},{"issue":"1","key":"1277_CR14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-065X.2011.01088.x","volume":"246","author":"SC Sun","year":"2012","unstructured":"S.C. Sun, The noncanonical NF-kappaB pathway. Immunol. Rev. 246(1), 125\u2013140 (2012)","journal-title":"Immunol. Rev."},{"issue":"4873","key":"1277_CR15","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1126\/science.2843985","volume":"241","author":"DW Ballard","year":"1988","unstructured":"D.W. Ballard, E. Bohnlein, J.W. Lowenthal, Y. Wano, B.R. Franza, W.C. Greene, HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science 241(4873), 1652\u20131655 (1988)","journal-title":"Science"},{"issue":"4861","key":"1277_CR16","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1126\/science.2838905","volume":"241","author":"S Ruben","year":"1988","unstructured":"S. Ruben, Poteat H, T.H. Tan, K. Kawakami, R. Roeder, W. Haseltine, C.A. Rosen, Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. Science 241(4861), 89\u201392 (1988)","journal-title":"Science"},{"issue":"21","key":"1277_CR17","doi-asserted-by":"crossref","first-page":"11900","DOI":"10.1128\/JVI.00532-07","volume":"81","author":"M Higuchi","year":"2007","unstructured":"M. Higuchi, C. Tsubata, R. Kondo, S. Yoshida, M. Takahashi, M. Oie, Y. Tanaka, R. Mahieux, M. Matsuoka, M. Fujii, Cooperation of NF-kappaB2\/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line. J. Virol. 81(21), 11900\u201311907 (2007)","journal-title":"J. Virol."},{"issue":"23","key":"1277_CR18","doi-asserted-by":"crossref","first-page":"6805","DOI":"10.1093\/emboj\/20.23.6805","volume":"20","author":"G Xiao","year":"2001","unstructured":"G. Xiao, M.E. Cvijic, A. Fong, E.W. Harhaj, M.T. Uhlik, M. Waterfield, S.C. Sun, Retroviral oncoprotein Tax induces processing of NF-kappaB2\/p100 in T cells: evidence for the involvement of IKKalpha. EMBO J. 20(23), 6805\u20136815 (2001)","journal-title":"EMBO J."},{"key":"1277_CR19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1742-4690-6-83","volume":"6","author":"T Shoji","year":"2009","unstructured":"T. Shoji, M. Higuchi, R. Kondo, M. Takahashi, M. Oie, Y. Tanaka, Y. Aoyagi, M. Fujii, Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2. Retrovirology 6, 83 (2009)","journal-title":"Retrovirology"},{"issue":"2","key":"1277_CR20","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1378\/chest.11-1730","volume":"141","author":"D Kaur","year":"2012","unstructured":"D. Kaur, C. Brightling, OX40\/OX40 ligand interactions in T-cell regulation and asthma. Chest 141(2), 494\u2013499 (2012)","journal-title":"Chest"},{"key":"1277_CR21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0065-2776(10)05003-0","volume":"105","author":"N Ishii","year":"2010","unstructured":"N. Ishii, T. Takahashi, P. Soroosh, K. Sugamura, OX40\u2013OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv. Immunol. 105, 63\u201398 (2010)","journal-title":"Adv. Immunol."},{"issue":"23","key":"1277_CR22","doi-asserted-by":"crossref","first-page":"14119","DOI":"10.1074\/jbc.273.23.14119","volume":"273","author":"K Ohtani","year":"1998","unstructured":"K. Ohtani, A. Tsujimoto, T. Tsukahara, N. Numata, S. Miura, K. Sugamura, M. Nakamura, Molecular mechanisms of promoter regulation of the gp34 gene that is trans-activated by an oncoprotein Tax of human T cell leukemia virus type I. J. Biol. Chem. 273(23), 14119\u201314129 (1998)","journal-title":"J. Biol. Chem."},{"issue":"3","key":"1277_CR23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1349-7006.1996.tb00210.x","volume":"87","author":"N Higashimura","year":"1996","unstructured":"N. Higashimura, N. Takasawa, Y. Tanaka, M. Nakamura, K. Sugamura, Induction of OX40, a receptor of gp34, on T cells by trans-acting transcriptional activator, Tax, of human T-cell leukemia virus type I. Jpn. J. Cancer Res. 87(3), 227\u2013231 (1996)","journal-title":"Jpn. J. Cancer Res."},{"issue":"3","key":"1277_CR24","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1128\/MCB.11.3.1313","volume":"11","author":"S Miura","year":"1991","unstructured":"S. Miura, K. Ohtani, N. Numata, M. Niki, K. Ohbo, Y. Ina, T. Gojobori, Y. Tanaka, H. Tozawa, M. Nakamura et al., Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax. Mol. Cell. Biol. 11(3), 1313\u20131325 (1991)","journal-title":"Mol. Cell. Biol."},{"issue":"6","key":"1277_CR25","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1084\/jem.152.6.1709","volume":"152","author":"S Gillis","year":"1980","unstructured":"S. Gillis, J. Watson, Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line. J. Exp. Med. 152(6), 1709\u20131719 (1980)","journal-title":"J. Exp. Med."},{"issue":"3","key":"1277_CR26","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0145-2126(85)90056-6","volume":"9","author":"L Vecchis De","year":"1985","unstructured":"L. De Vecchis, G. Graziani, B. Macchi, C. Grandori, S. Pastore, M. Popovic, R.C. Gallo, E. Bonmassar, Decline of natural cytotoxicity of human lymphocytes following infection with human T-cell leukemia\/lymphoma virus (HTLV). Leuk. Res. 9(3), 349\u2013355 (1985)","journal-title":"Leuk. Res."},{"issue":"1","key":"1277_CR27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1006\/viro.2000.0284","volume":"271","author":"MJ Lewis","year":"2000","unstructured":"M.J. Lewis, P. Novoa, R. Ishak, M. Ishak, M. Salemi, A.M. Vandamme, M.H. Kaplan, W.W. Hall, Isolation, cloning, and complete nucleotide sequence of a phenotypically distinct Brazilian isolate of human T-lymphotropic virus type II (HTLV-II). Virology 271(1), 142\u2013154 (2000)","journal-title":"Virology"},{"issue":"4","key":"1277_CR28","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/ijc.2910480423","volume":"48","author":"Y Tanaka","year":"1991","unstructured":"Y. Tanaka, A. Yoshida, H. Tozawa, H. Shida, H. Nyunoya, K. Shimotohno, Production of a recombinant human T-cell leukemia virus type-I trans-activator (tax1) antigen and its utilization for generation of monoclonal antibodies against various epitopes on the tax1 antigen. Int. J. Cancer 48(4), 623\u2013630 (1991)","journal-title":"Int. J. Cancer"},{"issue":"2","key":"1277_CR29","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/ijc.2910410213","volume":"41","author":"H Tozawa","year":"1988","unstructured":"H. Tozawa, S. Andoh, Y. Takayama, Y. Tanaka, B. Lee, H. Nakamura, M. Hayami, Y. Hinuma, Species-dependent antigenicity of the 34-kDa glycoprotein found on the membrane of various primate lymphocytes transformed by human T-cell leukemia virus type-I (HTLV-I) and simian T-cell leukemia virus (STLV-I). Int. J. Cancer 41(2), 231\u2013238 (1988)","journal-title":"Int. J. Cancer"},{"issue":"6","key":"1277_CR30","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.immuni.2015.05.012","volume":"42","author":"C Jacquemin","year":"2015","unstructured":"C. Jacquemin, N. Schmitt, C. Contin-Bordes, Y. Liu, P. Narayanan, J. Seneschal, T. Maurouard, D. Dougall, E.S. Davizon, H. Dumortier, I. Douchet, L. Raffray, C. Richez, E. Lazaro, P. Duffau, M.E. Truchetet, L. Khoryati, P. Mercie, L. Couzi, P. Merville, T. Schaeverbeke, J.F. Viallard, J.L. Pellegrin, J.F. Moreau, S. Muller, S. Zurawski, R.L. Coffman, V. Pascual, H. Ueno, P. Blanco, OX40 ligand contributes to human lupus pathogenesis by promoting T follicular helper response. Immunity 42(6), 1159\u20131170 (2015)","journal-title":"Immunity"},{"issue":"9","key":"1277_CR31","first-page":"2391","volume":"8","author":"T Suzuki","year":"1993","unstructured":"T. Suzuki, H. Hirai, J. Fujisawa, T. Fujita, M. Yoshida, A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box. Oncogene 8(9), 2391\u20132397 (1993)","journal-title":"Oncogene"},{"issue":"11","key":"1277_CR32","first-page":"3099","volume":"9","author":"T Suzuki","year":"1994","unstructured":"T. Suzuki, H. Hirai, M. Yoshida, Tax protein of HTLV-1 interacts with the Rel homology domain of NF-kappa B p65 and c-Rel proteins bound to the NF-kappa B binding site and activates transcription. Oncogene 9(11), 3099\u20133105 (1994)","journal-title":"Oncogene"},{"issue":"2","key":"1277_CR33","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1128\/JVI.73.2.1271-1277.1999","volume":"73","author":"Y Iwanaga","year":"1999","unstructured":"Y. Iwanaga, T. Tsukahara, T. Ohashi, Y. Tanaka, M. Arai, M. Nakamura, K. Ohtani, Y. Koya, M. Kannagi, N. Yamamoto, M. Fujii, Human T-cell leukemia virus type 1 tax protein abrogates interleukin-2 dependence in a mouse T-cell line. J. Virol. 73(2), 1271\u20131277 (1999)","journal-title":"J. Virol."},{"key":"1277_CR34","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1742-4690-2-46","volume":"2","author":"C Tsubata","year":"2005","unstructured":"C. Tsubata, M. Higuchi, M. Takahashi, M. Oie, Y. Tanaka, F. Gejyo, M. Fujii, PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line. Retrovirology 2, 46 (2005)","journal-title":"Retrovirology"},{"issue":"6","key":"1277_CR35","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1128\/JVI.76.6.2648-2653.2002","volume":"76","author":"K Endo","year":"2002","unstructured":"K. Endo, A. Hirata, K. Iwai, M. Sakurai, M. Fukushi, M. Oie, M. Higuchi, W.W. Hall, F. Gejyo, M. Fujii, Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax. J. Virol. 76(6), 2648\u20132653 (2002)","journal-title":"J. Virol."},{"issue":"18","key":"1277_CR36","doi-asserted-by":"crossref","first-page":"11925","DOI":"10.1128\/JVI.79.18.11925-11934.2005","volume":"79","author":"A Niinuma","year":"2005","unstructured":"A. Niinuma, M. Higuchi, M. Takahashi, M. Oie, Y. Tanaka, F. Gejyo, N. Tanaka, K. Sugamura, L. Xie, P.L. Green, M. Fujii, Aberrant activation of the interleukin-2 autocrine loop through the nuclear factor of activated T cells by nonleukemogenic human T-cell leukemia virus type 2 but not by leukemogenic type 1 virus. J. Virol. 79(18), 11925\u201311934 (2005)","journal-title":"J. Virol."},{"issue":"1","key":"1277_CR37","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11262-012-0831-9","volume":"46","author":"M Imai","year":"2013","unstructured":"M. Imai, M. Higuchi, H. Kawamura, M. Yoshita, M. Takahashi, M. Oie, H. Matsuki, Y. Tanaka, Y. Aoyagi, M. Fujii, Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4\u00a0+\u00a0T cells. Virus Genes 46(1), 39\u201346 (2013)","journal-title":"Virus Genes"},{"issue":"41","key":"1277_CR38","doi-asserted-by":"crossref","first-page":"43307","DOI":"10.1074\/jbc.M400497200","volume":"279","author":"L Meertens","year":"2004","unstructured":"L. Meertens, S. Chevalier, R. Weil, A. Gessain, R. Mahieux, A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution. J. Biol. Chem. 279(41), 43307\u201343320 (2004)","journal-title":"J. Biol. Chem."},{"issue":"1","key":"1277_CR39","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/viro.1996.0126","volume":"217","author":"OJ Semmes","year":"1996","unstructured":"O.J. Semmes, F. Majone, C. Cantemir, L. Turchetto, B. Hjelle, K.T. Jeang, HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs. Virology 217(1), 373\u2013379 (1996)","journal-title":"Virology"},{"issue":"44","key":"1277_CR40","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1038\/sj.onc.1203008","volume":"18","author":"T Suzuki","year":"1999","unstructured":"T. Suzuki, Y. Ohsugi, M. Uchida-Toita, T. Akiyama, M. Yoshida, Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control. Oncogene 18(44), 5967\u20135972 (1999)","journal-title":"Oncogene"},{"issue":"1","key":"1277_CR41","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.virol.2003.10.006","volume":"318","author":"A Hirata","year":"2004","unstructured":"A. Hirata, M. Higuchi, A. Niinuma, M. Ohashi, M. Fukushi, M. Oie, T. Akiyama, Y. Tanaka, F. Gejyo, M. Fujii, PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line. Virology 318(1), 327\u2013336 (2004)","journal-title":"Virology"},{"issue":"3","key":"1277_CR42","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/cas.12087","volume":"104","author":"GN Makokha","year":"2013","unstructured":"G.N. Makokha, M. Takahashi, M. Higuchi, S. Saito, Y. Tanaka, M. Fujii, Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-1. Cancer Sci. 104(3), 313\u2013320 (2013)","journal-title":"Cancer Sci."},{"issue":"1","key":"1277_CR43","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.virol.2003.11.014","volume":"320","author":"M Ohashi","year":"2004","unstructured":"M. Ohashi, M. Sakurai, M. Higuchi, N. Mori, M. Fukushi, M. Oie, R.J. Coffey, K. Yoshiura, Y. Tanaka, M. Uchiyama, M. Hatanaka, M. Fujii, Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3. Virology 320(1), 52\u201362 (2004)","journal-title":"Virology"},{"key":"1277_CR44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1742-4690-3-71","volume":"3","author":"K Ishioka","year":"2006","unstructured":"K. Ishioka, M. Higuchi, M. Takahashi, S. Yoshida, M. Oie, Y. Tanaka, S. Takahashi, L. Xie, P.L. Green, M. Fujii, Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein. Retrovirology 3, 71 (2006)","journal-title":"Retrovirology"},{"issue":"2","key":"1277_CR45","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s11262-008-0259-4","volume":"37","author":"M Okajima","year":"2008","unstructured":"M. Okajima, M. Takahashi, M. Higuchi, T. Ohsawa, S. Yoshida, Y. Yoshida, M. Oie, Y. Tanaka, F. Gejyo, M. Fujii, Human T-cell leukemia virus type 1 Tax induces an aberrant clustering of the tumor suppressor Scribble through the PDZ domain-binding motif dependent and independent interaction. Virus Genes 37(2), 231\u2013240 (2008)","journal-title":"Virus Genes"},{"issue":"45","key":"1277_CR46","doi-asserted-by":"crossref","first-page":"33132","DOI":"10.1074\/jbc.M702279200","volume":"282","author":"C Arpin-Andre","year":"2007","unstructured":"C. Arpin-Andre, J.M. Mesnard, The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells. J. Biol. Chem. 282(45), 33132\u201333141 (2007)","journal-title":"J. Biol. Chem."},{"issue":"5","key":"1277_CR47","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1182\/blood-2005-03-1333","volume":"107","author":"L Xie","year":"2006","unstructured":"L. Xie, B. Yamamoto, A. Haoudi, O.J. Semmes, P.L. Green, PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo. Blood 107(5), 1980\u20131988 (2006)","journal-title":"Blood"}],"container-title":["Virus Genes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-015-1277-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11262-015-1277-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-015-1277-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,13]],"date-time":"2020-09-13T16:57:08Z","timestamp":1600016228000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11262-015-1277-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,6]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["1277"],"URL":"https:\/\/doi.org\/10.1007\/s11262-015-1277-7","relation":{},"ISSN":["0920-8569","1572-994X"],"issn-type":[{"type":"print","value":"0920-8569"},{"type":"electronic","value":"1572-994X"}],"subject":[],"published":{"date-parts":[[2016,1,6]]}}}