{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T18:56:19Z","timestamp":1772304979862,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T00:00:00Z","timestamp":1564963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T00:00:00Z","timestamp":1564963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31570163"],"award-info":[{"award-number":["31570163"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Youth Project of State Key Laboratory of Respiratory Disease","award":["SKLRD-QN-201713"],"award-info":[{"award-number":["SKLRD-QN-201713"]}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"crossref","award":["2018YFC1200100"],"award-info":[{"award-number":["2018YFC1200100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virus Genes"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1007\/s11262-019-01698-4","type":"journal-article","created":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T14:02:53Z","timestamp":1565013773000},"page":"769-778","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Molecular evolution of human adenovirus type 16 through multiple recombination events"],"prefix":"10.1007","volume":"55","author":[{"given":"Xingui","family":"Tian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongkai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,8,5]]},"reference":[{"issue":"11","key":"1698_CR1","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1099\/jgv.0.000947","volume":"98","author":"EE Espinola","year":"2017","unstructured":"Espinola EE, Barrios JC, Russomando G, Mirazo S, Arbiza J (2017) Computational analysis of a species D human adenovirus provides evidence of a novel virus. J Gen Virol 98(11):2810\u20132820","journal-title":"J Gen Virol"},{"key":"1698_CR2","doi-asserted-by":"crossref","first-page":"5701","DOI":"10.1128\/JVI.00354-11","volume":"85","author":"D Seto","year":"2011","unstructured":"Seto D, Chodosh J, Brister JR, Jones MS, Members of the Adenovirus Research C (2011) Using the whole-genome sequence to characterize and name human adenoviruses. J Virol 85:5701\u20135702","journal-title":"J Virol"},{"key":"1698_CR3","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1002\/jmv.24749","volume":"89","author":"H Yoshitomi","year":"2017","unstructured":"Yoshitomi H, Sera N, Gonzalez G, Hanaoka N, Fujimoto T (2017) First isolation of a new type of human adenovirus (genotype 79), species Human mastadenovirus B (B2) from sewage water in Japan. J Med Virol 89:1192\u20131200","journal-title":"J Med Virol"},{"key":"1698_CR4","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1002\/jmv.25041","volume":"90","author":"S Hashimoto","year":"2018","unstructured":"Hashimoto S, Gonzalez G, Harada S, Oosako H, Hanaoka N, Hinokuma R, Fujimoto T (2018) Recombinant type Human mastadenovirus D85 associated with epidemic keratoconjunctivitis since 2015 in Japan. J Med Virol 90:881\u2013889","journal-title":"J Med Virol"},{"key":"1698_CR5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/rmv.589","volume":"18","author":"L Lenaerts","year":"2008","unstructured":"Lenaerts L, De Clercq E, Naesens L (2008) Clinical features and treatment of adenovirus infections. Rev Med Virol 18:357\u2013374","journal-title":"Rev Med Virol"},{"key":"1698_CR6","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1007\/s11908-014-0416-y","volume":"16","author":"U Sandkovsky","year":"2014","unstructured":"Sandkovsky U, Vargas L, Florescu DF (2014) Adenovirus: current epidemiology and emerging approaches to prevention and treatment. Curr Infect Dis Rep 16:416","journal-title":"Curr Infect Dis Rep"},{"key":"1698_CR7","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1128\/JCM.01694-09","volume":"48","author":"MP Walsh","year":"2010","unstructured":"Walsh MP, Seto J, Jones MS, Chodosh J, Xu W, Seto D (2010) Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen. J Clin Microbiol 48:991\u2013993","journal-title":"J Clin Microbiol"},{"key":"1698_CR8","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1128\/JCM.00282-09","volume":"47","author":"Z Yang","year":"2009","unstructured":"Yang Z, Zhu Z, Tang L, Wang L, Tan X, Yu P, Zhang Y, Tian X, Wang J, Zhang Y, Li D, Xu W (2009) Genomic analyses of recombinant adenovirus type 11a in China. J Clin Microbiol 47:3082\u20133090","journal-title":"J Clin Microbiol"},{"key":"1698_CR9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.virol.2013.05.014","volume":"443","author":"S Dehghan","year":"2013","unstructured":"Dehghan S, Seto J, Liu EB, Walsh MP, Dyer DW, Chodosh J, Seto D (2013) Computational analysis of four human adenovirus type 4 genomes reveals molecular evolution through two interspecies recombination events. Virology 443:197\u2013207","journal-title":"Virology"},{"key":"1698_CR10","doi-asserted-by":"crossref","first-page":"e00159-18","DOI":"10.1128\/JVI.00159-18","volume":"92","author":"MJ Iampietro","year":"2018","unstructured":"Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH (2018) Immunogenicity and cross-reactivity of rhesus adenoviral vectors. J Virol 92:e00159-18","journal-title":"J Virol"},{"key":"1698_CR11","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1172\/JCI60988","volume":"122","author":"NL Michael","year":"2012","unstructured":"Michael NL (2012) Rare serotype adenoviral vectors for HIV vaccine development. J Clin Invest 122:25\u201327","journal-title":"J Clin Invest"},{"key":"1698_CR12","doi-asserted-by":"crossref","first-page":"15265","DOI":"10.1128\/JVI.79.24.15265-15276.2005","volume":"79","author":"I Madisch","year":"2005","unstructured":"Madisch I, Harste G, Pommer H, Heim A (2005) Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy. J Virol 79:15265\u201315276","journal-title":"J Virol"},{"key":"1698_CR13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1006\/viro.1995.1474","volume":"212","author":"P Pring-Akerblom","year":"1995","unstructured":"Pring-Akerblom P, Trijssenaar FE, Adrian T (1995) Sequence characterization and comparison of human adenovirus subgenus B and E hexons. Virology 212:232\u2013236","journal-title":"Virology"},{"key":"1698_CR14","doi-asserted-by":"crossref","first-page":"12635","DOI":"10.1128\/JVI.79.20.12635-12642.2005","volume":"79","author":"K Ebner","year":"2005","unstructured":"Ebner K, Pinsker W, Lion T (2005) Comparative sequence analysis of the hexon gene in the entire spectrum of human adenovirus serotypes: phylogenetic, taxonomic, and clinical implications. J Virol 79:12635\u201312642","journal-title":"J Virol"},{"key":"1698_CR15","first-page":"310","volume":"79","author":"RR Rafajko","year":"1964","unstructured":"Rafajko RR (1964) Production and standardization of adenovirus types 1 to 18 reference antisera. Am J Hyg 79:310\u2013319","journal-title":"Am J Hyg"},{"key":"1698_CR16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0166-0934(87)90001-2","volume":"16","author":"R Wigand","year":"1987","unstructured":"Wigand R (1987) Pitfalls in the identification of adenoviruses. J Virol Methods 16:161\u2013169","journal-title":"J Virol Methods"},{"key":"1698_CR17","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF01316753","volume":"121","author":"JC Hierholzer","year":"1991","unstructured":"Hierholzer JC, Stone YO, Broderson JR (1991) Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch Virol 121:179\u2013197","journal-title":"Arch Virol"},{"key":"1698_CR18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1101\/gr.4337206","volume":"16","author":"B Lin","year":"2006","unstructured":"Lin B, Wang Z, Vora GJ, Thornton JA, Schnur JM, Thach DC, Blaney KM, Ligler AG, Malanoski AP, Santiago J, Walter EA, Agan BK, Metzgar D, Seto D, Daum LT, Kruzelock R, Rowley RK, Hanson EH, Tibbetts C, Stenger DA (2006) Broad-spectrum respiratory tract pathogen identification using resequencing DNA microarrays. Genome Res 16:527\u2013535","journal-title":"Genome Res"},{"key":"1698_CR19","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/1471-2164-7-150","volume":"7","author":"V Tcherepanov","year":"2006","unstructured":"Tcherepanov V, Ehlers A, Upton C (2006) Genome Annotation Transfer Utility (GATU): rapid annotation of viral genomes using a closely related reference genome. BMC Genomics 7:150","journal-title":"BMC Genomics"},{"key":"1698_CR20","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1093\/molbev\/msx149","volume":"34","author":"V Lefort","year":"2017","unstructured":"Lefort V, Longueville JE, Gascuel O (2017) SMS: smart Model Selection in PhyML. Mol Biol Evol 34:2422\u20132424","journal-title":"Mol Biol Evol"},{"key":"1698_CR21","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/sysbio\/syq010","volume":"59","author":"S Guindon","year":"2010","unstructured":"Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O (2010) New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 59:307\u2013321","journal-title":"Syst Biol"},{"key":"1698_CR22","doi-asserted-by":"crossref","first-page":"W242","DOI":"10.1093\/nar\/gkw290","volume":"44","author":"I Letunic","year":"2016","unstructured":"Letunic I, Bork P (2016) Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. Nucleic Acids Res 44:W242\u2013W245","journal-title":"Nucleic Acids Res"},{"key":"1698_CR23","doi-asserted-by":"crossref","first-page":"vev003","DOI":"10.1093\/ve\/vev003","volume":"1","author":"DP Martin","year":"2015","unstructured":"Martin DP, Murrell B, Golden M, Khoosal A, Muhire B (2015) RDP4: detection and analysis of recombination patterns in virus genomes. Virus Evol 1:vev003","journal-title":"Virus Evol"},{"key":"1698_CR24","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/bioinformatics\/16.6.562","volume":"16","author":"D Martin","year":"2000","unstructured":"Martin D, Rybicki E (2000) RDP: detection of recombination amongst aligned sequences. Bioinformatics 16:562\u2013563","journal-title":"Bioinformatics"},{"key":"1698_CR25","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1006\/viro.1999.0056","volume":"265","author":"M Padidam","year":"1999","unstructured":"Padidam M, Sawyer S, Fauquet CM (1999) Possible emergence of new geminiviruses by frequent recombination. Virology 265:218\u2013225","journal-title":"Virology"},{"key":"1698_CR26","first-page":"126","volume":"34","author":"JM Smith","year":"1992","unstructured":"Smith JM (1992) Analyzing the mosaic structure of genes. J Mol Evol 34:126\u2013129","journal-title":"J Mol Evol"},{"key":"1698_CR27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1089\/aid.2005.21.98","volume":"21","author":"DP Martin","year":"2005","unstructured":"Martin DP, Posada D, Crandall KA, Williamson C (2005) A modified bootscan algorithm for automated identification of recombinant sequences and recombination breakpoints. AIDS Res Hum Retrovir 21:98\u2013102","journal-title":"AIDS Res Hum Retrovir"},{"key":"1698_CR28","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/bioinformatics\/16.7.573","volume":"16","author":"MJ Gibbs","year":"2000","unstructured":"Gibbs MJ, Armstrong JS, Gibbs AJ (2000) Sister-scanning: a Monte Carlo procedure for assessing signals in recombinant sequences. Bioinformatics 16:573\u2013582","journal-title":"Bioinformatics"},{"key":"1698_CR29","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1534\/genetics.106.068874","volume":"176","author":"MF Boni","year":"2007","unstructured":"Boni MF, Posada D, Feldman MW (2007) An exact nonparametric method for inferring mosaic structure in sequence triplets. Genetics 176:1035\u20131047","journal-title":"Genetics"},{"key":"1698_CR30","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1128\/JVI.70.4.2116-2123.1996","volume":"70","author":"J Gall","year":"1996","unstructured":"Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E (1996) Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol 70:2116\u20132123","journal-title":"J Virol"},{"key":"1698_CR31","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.virol.2004.12.029","volume":"333","author":"S Roy","year":"2005","unstructured":"Roy S, Clawson DS, Calcedo R, Lebherz C, Sanmiguel J, Wu D, Wilson JM (2005) Use of chimeric adenoviral vectors to assess capsid neutralization determinants. Virology 333:207\u2013214","journal-title":"Virology"},{"key":"1698_CR32","doi-asserted-by":"crossref","first-page":"7179","DOI":"10.4049\/jimmunol.174.11.7179","volume":"174","author":"SM Sumida","year":"2005","unstructured":"Sumida SM, Truitt DM, Lemckert AA, Vogels R, Custers JH, Addo MM, Lockman S, Peter T, Peyerl FW, Kishko MG, Jackson SS, Gorgone DA, Lifton MA, Essex M, Walker BD, Goudsmit J, Havenga MJ, Barouch DH (2005) Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein. J Immunol 174:7179\u20137185","journal-title":"J Immunol"},{"key":"1698_CR33","doi-asserted-by":"crossref","first-page":"e01643-17","DOI":"10.1128\/JVI.01643-17","volume":"92","author":"X Tian","year":"2018","unstructured":"Tian X, Qiu H, Zhou Z, Wang S, Fan Y, Li X, Chu R, Li H, Zhou R, Wang H (2018) Identification of a critical and conformational neutralizing epitope in human adenovirus type 4 hexon. J Virol 92:e01643-17","journal-title":"J Virol"},{"key":"1698_CR34","doi-asserted-by":"crossref","first-page":"12775","DOI":"10.1128\/JVI.76.24.12775-12782.2002","volume":"76","author":"H Wu","year":"2002","unstructured":"Wu H, Dmitriev I, Kashentseva E, Seki T, Wang M, Curiel DT (2002) Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon. J Virol 76:12775\u201312782","journal-title":"J Virol"},{"key":"1698_CR35","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.virol.2012.12.014","volume":"437","author":"B Yu","year":"2013","unstructured":"Yu B, Dong J, Wang C, Zhan Y, Zhang H, Wu J, Kong W, Yu X (2013) Characteristics of neutralizing antibodies to adenovirus capsid proteins in human and animal sera. Virology 437:118\u2013123","journal-title":"Virology"},{"key":"1698_CR36","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.virusres.2011.06.017","volume":"160","author":"X Tian","year":"2011","unstructured":"Tian X, Su X, Li H, Li X, Zhou Z, Liu W, Zhou R (2011) Construction and characterization of human adenovirus serotype 3 packaged by serotype 7 hexon. Virus Res 160:214\u2013220","journal-title":"Virus Res"},{"key":"1698_CR37","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1128\/JVI.06165-11","volume":"86","author":"RR Bradley","year":"2012","unstructured":"Bradley RR, Maxfield LF, Lynch DM, Iampietro MJ, Borducchi EN, Barouch DH (2012) Adenovirus serotype 5-specific neutralizing antibodies target multiple hexon hypervariable regions. J Virol 86:1267\u20131272","journal-title":"J Virol"},{"key":"1698_CR38","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1128\/JVI.02023-06","volume":"81","author":"SL Pichla-Gollon","year":"2007","unstructured":"Pichla-Gollon SL, Drinker M, Zhou X, Xue F, Rux JJ, Gao GP, Wilson JM, Ertl HC, Burnett RM, Bergelson JM (2007) Structure-based identification of a major neutralizing site in an adenovirus hexon. J Virol 81:1680\u20131689","journal-title":"J Virol"},{"key":"1698_CR39","doi-asserted-by":"crossref","first-page":"7964","DOI":"10.1128\/JVI.07076-11","volume":"86","author":"H Qiu","year":"2012","unstructured":"Qiu H, Li X, Tian X, Zhou Z, Xing K, Li H, Tang N, Liu W, Bai P, Zhou R (2012) Serotype-specific neutralizing antibody epitopes of human adenovirus type 3 (HAdV-3) and HAdV-7 reside in multiple hexon hypervariable regions. J Virol 86:7964\u20137975","journal-title":"J Virol"},{"key":"1698_CR40","doi-asserted-by":"crossref","first-page":"9553","DOI":"10.1128\/JVI.77.17.9553-9566.2003","volume":"77","author":"JJ Rux","year":"2003","unstructured":"Rux JJ, Kuser PR, Burnett RM (2003) Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods. J Virol 77:9553\u20139566","journal-title":"J Virol"},{"key":"1698_CR41","doi-asserted-by":"crossref","first-page":"5632","DOI":"10.3390\/v7102896","volume":"7","author":"X Tian","year":"2015","unstructured":"Tian X, Ma Q, Jiang Z, Huang J, Liu Q, Lu X, Luo Q, Zhou R (2015) Identification and application of neutralizing epitopes of human adenovirus type 55 hexon protein. Viruses 7:5632\u20135642","journal-title":"Viruses"},{"key":"1698_CR42","doi-asserted-by":"crossref","first-page":"5103","DOI":"10.1016\/j.vaccine.2009.06.041","volume":"27","author":"X Yuan","year":"2009","unstructured":"Yuan X, Qu Z, Wu X, Wang Y, Liu L, Wei F, Gao H, Shang L, Zhang H, Cui H, Zhao Y, Wu N, Tang Y, Qin L (2009) Molecular modeling and epitopes mapping of human adenovirus type 3 hexon protein. Vaccine 27:5103\u20135110","journal-title":"Vaccine"},{"key":"1698_CR43","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF01314652","volume":"101","author":"QG Li","year":"1988","unstructured":"Li QG, Wadell G (1988) The degree of genetic variability among adenovirus type 4 strains isolated from man and chimpanzee. Arch Virol 101:65\u201377","journal-title":"Arch Virol"},{"key":"1698_CR44","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3201\/eid2402.171407","volume":"24","author":"AE Kajon","year":"2018","unstructured":"Kajon AE, Lamson DM, Bair CR, Lu X, Landry ML, Menegus M, Erdman DD, St. George K (2018) Adenovirus type 4 respiratory infections among civilian adults, Northeastern United States, 2011-2015(1). Emerg Infect Dis 24:201\u2013209","journal-title":"Emerg Infect Dis"},{"key":"1698_CR45","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1128\/JCM.02289-09","volume":"48","author":"AE Kajon","year":"2010","unstructured":"Kajon AE, Dickson LM, Murtagh P, Viale D, Carballal G, Echavarria M (2010) Molecular characterization of an adenovirus 3-16 intertypic recombinant isolated in Argentina from an infant hospitalized with acute respiratory infection. J Clin Microbiol 48:1494\u20131496","journal-title":"J Clin Microbiol"},{"key":"1698_CR46","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1089\/10430340252769824","volume":"13","author":"R Youil","year":"2002","unstructured":"Youil R, Toner TJ, Su Q, Chen M, Tang A, Bett AJ, Casimiro D (2002) Hexon gene switch strategy for the generation of chimeric recombinant adenovirus. Hum Gene Ther 13:311\u2013320","journal-title":"Hum Gene Ther"}],"container-title":["Virus Genes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-019-01698-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11262-019-01698-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-019-01698-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T23:30:34Z","timestamp":1596497434000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11262-019-01698-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,5]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["1698"],"URL":"https:\/\/doi.org\/10.1007\/s11262-019-01698-4","relation":{},"ISSN":["0920-8569","1572-994X"],"issn-type":[{"value":"0920-8569","type":"print"},{"value":"1572-994X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,5]]},"assertion":[{"value":"30 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}