{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:19:47Z","timestamp":1792783187088,"version":"4.5.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Industrial Research Projects at Huaihua Vocational and Technical College","award":["No. HHZYHX2025001"],"award-info":[{"award-number":["No. HHZYHX2025001"]}],"id":[{"id":"https:\/\/ror.org\/035t3zm42","id-type":"ROR","asserted-by":"crossref"}]},{"name":"the 2023 Hunan Provincial Department of Education Scientific Research Project","award":["No. 23B1073"],"award-info":[{"award-number":["No. 23B1073"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virus Genes"],"DOI":"10.1007\/s11262-026-02287-y","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:10:26Z","timestamp":1792012226000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolation, complete genome characterization and phylogenetic analysis of getah virus from a diseased pig herd in Hunan Province, China"],"prefix":"10.1007","author":[{"given":"Can","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renke","family":"Qing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoliang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyou","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"2287_CR1","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1099\/jgv.0.001072","volume":"99","author":"R Chen","year":"2018","unstructured":"Chen R, Mukhopadhyay S, Merits A, Bolling B, Nasar F, Coffey LL, Powers A, Weaver SC, Ictv Report C (2018) ICTV virus taxonomy profile: Togaviridae. J Gen Virol 99:761\u2013762","journal-title":"J Gen Virol"},{"key":"2287_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11080945","author":"B Li","year":"2022","unstructured":"Li B, Wang H, Liang G (2022) Getah virus (alphavirus): an emerging, spreading zoonotic virus. Pathogens. https:\/\/doi.org\/10.3390\/pathogens11080945","journal-title":"Pathogens"},{"key":"2287_CR3","doi-asserted-by":"publisher","first-page":"e1037","DOI":"10.1111\/tbed.14395","volume":"69","author":"N Shi","year":"2022","unstructured":"Shi N, Zhu X, Qiu X, Cao X, Jiang Z, Lu H, Jin N (2022) Origin, genetic diversity, adaptive evolution and transmission dynamics of Getah virus. Transbound Emerg Dis 69:e1037\u2013e1050","journal-title":"Transbound Emerg Dis"},{"key":"2287_CR4","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00483-24","volume":"12","author":"PP Chu","year":"2024","unstructured":"Chu PP, Guo H, Zhou X, Chen SN, Sun X, Tian S, Zou YG, Li CL, Zhang R, Zhai SL (2024) Emergence of a novel GIII Getah virus variant in pigs in Guangdong, China, 2023. Microbiol Spectr 12:e00483-24","journal-title":"Microbiol Spectr"},{"key":"2287_CR5","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13567-025-01547-3","volume":"56","author":"H Liu","year":"2025","unstructured":"Liu H, Qi Z, Tian L, Chen Z, Li H, Liu L, Liu S, Li S, Sun J, Shao Y, Song X, Tu J, Zhu L, Qi K, Wang Z (2025) Getah virus nonstructural protein 2 suppresses interferon-beta production by interrupting interferon regulatory factor 3 activation. Vet Res 56:110","journal-title":"Vet Res"},{"key":"2287_CR6","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1111\/tbed.12867","volume":"65","author":"T Yang","year":"2018","unstructured":"Yang T, Li R, Hu Y, Yang L, Zhao D, Du L, Li J, Ge M, Yu X (2018) An outbreak of Getah virus infection among pigs in China, 2017. Transbound Emerg Dis 65:632\u2013637","journal-title":"Transbound Emerg Dis"},{"key":"2287_CR7","doi-asserted-by":"publisher","first-page":"126136","DOI":"10.1016\/j.vaccine.2024.07.037","volume":"42","author":"Q Miao","year":"2024","unstructured":"Miao Q, Nguyen W, Zhu J, Liu G, van Oers MM, Tang B, Yan K, Larcher T, Suhrbier A, Pijlman GP (2024) A getah virus-like-particle vaccine provides complete protection from viremia and arthritis in wild-type mice. Vaccine 42:126136","journal-title":"Vaccine"},{"key":"2287_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2025.1513392","volume":"15","author":"Y Yuan","year":"2025","unstructured":"Yuan Y, Hao Y, Peng C, Zhang D, Ma W, Xiao P, Li N (2025) From transmission to adaptive evolution: genomic surveillance of Getah virus. Front Cell Infect Microbiol 15:1513392","journal-title":"Front Cell Infect Microbiol"},{"issue":"Pt 11","key":"2287_CR9","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1099\/0022-1317-65-11-1899","volume":"65","author":"K Morita","year":"1984","unstructured":"Morita K, Igarashi A (1984) Oligonucleotide fingerprint analysis of strains of Getah virus isolated in Japan and Malaysia. J Gen Virol 65(Pt 11):1899\u20131908","journal-title":"J Gen Virol"},{"key":"2287_CR10","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1023\/A:1005079229232","volume":"30","author":"CM Brown","year":"1998","unstructured":"Brown CM, Timoney PJ (1998) Getah virus infection of Indian horses. Trop Anim Health Prod 30:241\u2013252","journal-title":"Trop Anim Health Prod"},{"key":"2287_CR11","doi-asserted-by":"publisher","first-page":"470","DOI":"10.4269\/ajtmh.2005.73.470","volume":"73","author":"JE Bryant","year":"2005","unstructured":"Bryant JE, Crabtree MB, Nam VS, Yen NT, Duc HM, Miller BR (2005) Isolation of arboviruses from mosquitoes collected in northern Vietnam. Am J Trop Med Hyg 73:470\u2013473","journal-title":"Am J Trop Med Hyg"},{"key":"2287_CR12","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/S0749-0739(17)30099-8","volume":"16","author":"Y Fukunaga","year":"2000","unstructured":"Fukunaga Y, Kumanomido T, Kamada M (2000) Getah virus as an equine pathogen. Vet Clin North Am Equine Pract 16:605\u2013617","journal-title":"Vet Clin North Am Equine Pract"},{"key":"2287_CR13","doi-asserted-by":"publisher","first-page":"351","DOI":"10.4269\/ajtmh.1979.28.351","volume":"28","author":"M Kanamitsu","year":"1979","unstructured":"Kanamitsu M, Taniguchi K, Urasawa S, Ogata T, Wada Y, Wada Y, Saroso JS (1979) Geographic distribution of arbovirus antibodies in indigenous human populations in the Indo-Australian archipelago. Am J Trop Med Hyg 28:351\u2013363","journal-title":"Am J Trop Med Hyg"},{"key":"2287_CR14","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/0035-9203(81)90346-1","volume":"75","author":"TG Ksiazek","year":"1981","unstructured":"Ksiazek TG, Trosper JH, Cross JH, Basaca-Sevilla V (1981) Isolation of Getah virus from Nueva Ecija Province, Republic of the Philippines. Trans R Soc Trop Med Hyg 75:312\u2013313","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"2287_CR15","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.meegid.2017.08.016","volume":"55","author":"YY Li","year":"2017","unstructured":"Li YY, Liu H, Fu SH, Li XL, Guo XF, Li MH, Feng Y, Chen WX, Wang LH, Lei WW, Gao XY, Lv Z, He Y, Wang HY, Zhou HN, Wang GQ, Liang GD (2017) From discovery to spread: the evolution and phylogeny of Getah virus. Infect Genet Evol 55:48\u201355","journal-title":"Infect Genet Evol"},{"key":"2287_CR16","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.01416","volume":"10","author":"G Lu","year":"2019","unstructured":"Lu G, Ou J, Ji J, Ren Z, Hu X, Wang C, Li S (2019) Emergence of Getah virus infection in horse with fever in China, 2018. Front Microbiol 10:1416","journal-title":"Front Microbiol"},{"key":"2287_CR17","doi-asserted-by":"publisher","first-page":"883","DOI":"10.3201\/eid2105.141975","volume":"21","author":"M Nemoto","year":"2015","unstructured":"Nemoto M, Bannai H, Tsujimura K, Kobayashi M, Kikuchi T, Yamanaka T, Kondo T (2015) Getah virus infection among racehorses, Japan, 2014. Emerg Infect Dis 21:883\u2013885","journal-title":"Emerg Infect Dis"},{"key":"2287_CR18","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1603\/0022-2585-40.4.580","volume":"40","author":"MJ Turell","year":"2003","unstructured":"Turell MJ, O\u2019Guinn ML, Wasieloski LP Jr, Dohm DJ, Lee WJ, Cho HW, Kim HC, Burkett DA, Mores CN, Coleman RE, Klein TA (2003) Isolation of Japanese encephalitis and Getah viruses from mosquitoes (Diptera: Culicidae) collected near Camp Greaves, Gyonggi Province, Republic of Korea, 2000. J Med Entomol 40:580\u2013584","journal-title":"J Med Entomol"},{"key":"2287_CR19","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1089\/vbz.2024.0100","volume":"25","author":"YL Deng","year":"2025","unstructured":"Deng YL, Lin ZY, Lin R, Lu ZS, Yan XX, Li LX, Lu HJ, Bai X, Jin NY, Liu H (2025) Isolation and characterization of Getah virus GD2202 from mosquitoes in Foshan, China. Vector Borne Zoonotic Dis 25:269\u2013276","journal-title":"Vector Borne Zoonotic Dis"},{"key":"2287_CR20","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1089\/vbz.2018.2273","volume":"19","author":"Y Li","year":"2019","unstructured":"Li Y, Fu S, Guo X, Li X, Li M, Wang L, Gao X, Lei W, Cao L, Lu Z, He Y, Wang H, Zhou H, Liang G (2019) Serological survey of Getah virus in domestic animals in Yunnan Province, China. Vector Borne Zoonotic Dis 19:59\u201361","journal-title":"Vector Borne Zoonotic Dis"},{"key":"2287_CR21","doi-asserted-by":"crossref","unstructured":"Shi N, Li LX, Lu RG, Yan XJ, Liu H (2019). Highly Pathogenic Swine Getah Virus in Blue Foxes, Eastern China, 2017, In: Emerg Infect Dis.United States, 1252\u20131254.","DOI":"10.3201\/eid2506.181983"},{"key":"2287_CR22","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/0035-9203(85)90091-4","volume":"79","author":"I Takashima","year":"1985","unstructured":"Takashima I, Hashimoto N (1985) Getah virus in several species of mosquitoes. Trans R Soc Trop Med Hyg 79:546\u2013550","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"2287_CR23","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","volume":"35","author":"S Kumar","year":"2018","unstructured":"Kumar S, Stecher G, Li M, Knyaz C, Tamura K (2018) MEGA X: molecular evolutionary genetics analysis across computing platforms. Mol Biol Evol 35:1547\u20131549","journal-title":"Mol Biol Evol"},{"key":"2287_CR24","first-page":"350","volume":"80","author":"G Lu","year":"2020","unstructured":"Lu G, Chen R, Shao R, Dong N, Liu W, Li S (2020) Getah virus: an increasing threat in China. J Infect 80:350\u2013371","journal-title":"J Infect"},{"key":"2287_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2023.109742","volume":"281","author":"T Ren","year":"2023","unstructured":"Ren T, Zhou L, Min X, Sui M, Zhi X, Mo Y, Huang J, Zhang K, Liu W, Wang H, Wang X, Ouyang K, Chen Y, Huang W, Wei Z (2023) Development of a recombinant reporter Getah virus for antiviral drug screening assays. Vet Microbiol 281:109742","journal-title":"Vet Microbiol"}],"container-title":["Virus Genes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-026-02287-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11262-026-02287-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11262-026-02287-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:10:27Z","timestamp":1792012227000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11262-026-02287-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,14]]},"references-count":25,"alternative-id":["2287"],"URL":"https:\/\/doi.org\/10.1007\/s11262-026-02287-y","relation":{},"ISSN":["0920-8569","1572-994X"],"issn-type":[{"value":"0920-8569","type":"print"},{"value":"1572-994X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,14]]},"assertion":[{"value":"17 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflicts of interest.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study did not involve any live animal experimentation, experimental infection, or survival procedures performed on animals for research purposes. All clinical samples (spleen, lymph node, and blood) were collected from naturally diseased pigs that had already died or were euthanized for veterinary diagnostic purposes during an outbreak investigation on a commercial pig farm. Sample collection and pathological autopsy were performed by licensed veterinarians as part of routine disease diagnosis and emergency pathogen surveillance, following standard veterinary diagnostic procedures. Prior to sample collection, written informed consent was obtained from the farm owner. Because the study involved only post-mortem sampling of clinically diseased animals and did not include any manipulation of live animals for experimental purposes, formal ethical review by an Animal Ethics Committee was waived in accordance with the Chinese Guidelines for Ethical Review of Experimental Animal Welfare (GB\/T 35892\u20132018), which primarily applies to experimental animals used in research settings. All procedures were conducted in compliance with institutional and national guidelines for animal care and use. Institutional Biosafety Committee (IBC) approval for handling live GETV was obtained from Huaihua Vocational and Technical College (IBC approval no. HHZY\u2011IBC\u20112025\u2011003).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}