{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T23:31:52Z","timestamp":1775691112738,"version":"3.50.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,1,8]],"date-time":"2013-01-08T00:00:00Z","timestamp":1357603200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Microbiol Biotechnol"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1007\/s11274-013-1251-2","type":"journal-article","created":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T12:33:06Z","timestamp":1357561986000},"page":"923-932","source":"Crossref","is-referenced-by-count":28,"title":["Production of 3-nitropropionic acid by endophytic fungus Phomopsis longicolla isolated from Trichilia elegans A. JUSS ssp. elegans and evaluation of biological activity"],"prefix":"10.1007","volume":"29","author":[{"given":"Andressa Caroline","family":"Flores","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Alencar","family":"Pamphile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Helena","family":"Sarragiotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmar","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,1,8]]},"reference":[{"key":"1251_CR1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.phytochem.2009.09.024","volume":"71","author":"R Abdou","year":"2010","unstructured":"Abdou R, Scherlach K, Dahse HM, Sattler I, Hertweck C (2010) Botryorhodines A\u2013D, antifungal and cytotoxic depsidones from Botryosphaeria rhodina, and endophyte of the medicinal plant Bidens pilosa. Phytochemistry 71:110\u2013116. doi: 10.1016\/j.phytochem.2009.09.024","journal-title":"Phytochemistry"},{"issue":"4","key":"1251_CR2","first-page":"403","volume":"20","author":"SB Alves","year":"1985","unstructured":"Alves SB, Padua LEM, Azevedo EMVM, Almeida LC (1985) Controle da broca da cana-de-a\u00e7\u00facar pelo uso de Beauveria bassiana. Pesq Agropec Bras 20(4):403\u2013406","journal-title":"Pesq Agropec Bras"},{"issue":"2","key":"1251_CR3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0022-2011(02)00147-7","volume":"81","author":"SB Alves","year":"2002","unstructured":"Alves SB, Rossi LS, Lopes RB, Tamai MA, Pereira RM (2002) Beauveria bassiana yeast phase on agar medium and its pathogenicity against Diatraea saccharalis (Lepidoptera: Crambidae) and Tetranychus urticae (Acari: Tetranychidae). J Invert Pathol 81(2):70\u201377. doi: 10.1016\/S0022-2011(02)00147-7","journal-title":"J Invert Pathol"},{"key":"1251_CR4","unstructured":"Azevedo JL (1998) Microorganismos Endof\u00edticos. In: Melo ISE, Azevedo JL Ecologia Microbiana, Jaguari\u00fana, Editora Embrapa, pp 117\u2013137"},{"key":"1251_CR5","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4067\/S0716-97602010000400001","volume":"43","author":"J Bernardi-Wenzel","year":"2010","unstructured":"Bernardi-Wenzel J, Garcia A, Rubin filho CJ, Prioli AJ, Pamphile JA (2010) Evaluation of foliar fungal endophyte diversity and colonization of medicinal plant Luehea divaricata (Martius et Zuccarini). Biol Res 43:375\u2013384. doi: 10.4067\/S0716-97602010000400001","journal-title":"Biol Res"},{"issue":"2","key":"1251_CR6","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1590\/S1519-566X2005000200020","volume":"34","author":"PC Bogorni","year":"2005","unstructured":"Bogorni PC, Vendramim JD (2005) Efeito subletal de extratos aquosos de Trichilia spp. sobre o desenvolvimento de Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) em milho. Neotrop Entomol 34(2):311\u2013317. doi: 10.1590\/S1519-566X2005000200020","journal-title":"Neotrop Entomol"},{"key":"1251_CR7","doi-asserted-by":"crossref","unstructured":"Bortoli SA, D\u00f3ria HOS, Albergaria NMMS, Botti MV (2005) Aspectos biol\u00f3gicos e dano de Diatraea saccharalis (Fabr., 1794) (Lepidoptera:Pyralidae) em sorgo cultivado sob diferentes doses de nitrog\u00eanio e pot\u00e1ssio. Ci\u00eanc Agrotec 29: (2) 267\u2013273. doi: 10.1590\/S1413-70542005000200001","DOI":"10.1590\/S1413-70542005000200001"},{"issue":"3","key":"1251_CR8","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1128\/AAC.40.3.677","volume":"40","author":"DM Cappelletty","year":"1996","unstructured":"Cappelletty DM, Rybak MJ (1996) Comparison of methodologies for synergism testing of drug combinations against resistant strains of Pseudomonas aeruginosa. Antimicrob Agents Chemother 40(3):677\u2013683","journal-title":"Antimicrob Agents Chemother"},{"key":"1251_CR9","first-page":"103","volume":"68","author":"P Chomeheon","year":"2005","unstructured":"Chomeheon P, Wiyakrutta S, Sriubolmas N, Ngamrojanavanich N, Isarangkul D, Kittakoop P (2005) 3-nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? J Nat Prod 68:103\u20131105. doi: 10.1021\/np050036a","journal-title":"J Nat Prod"},{"key":"1251_CR10","unstructured":"Cole RJ, Cox RH (1981) Handbook of toxic fungal metabolites. Academic Press, New York, pp 755"},{"issue":"2","key":"1251_CR11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S1061-7361(00)80003-X","volume":"21","author":"PA Corning","year":"2000","unstructured":"Corning PA (2000) \u201cThe Synergism Hypothesis\u201d: on the concept of synergy and its role in the evolution of complex systems. J Soc Evol Sys 21(2):133\u2013172. doi: 10.1016\/S1061-7361(00)80003-X","journal-title":"J Soc Evol Sys"},{"key":"1251_CR12","doi-asserted-by":"crossref","unstructured":"Culvenor CCJ, Edgar LA, Mackay M (1989) Structure elucidation and absolute configuration of phomopsin A, a hexapeptide mycotoxin produced by Phomopsis leptostromiformis, tetrahed, 45: (8) 2351\u20132372. doi: 10.1016\/S0040-4020(01)83436-0","DOI":"10.1016\/S0040-4020(01)83436-0"},{"key":"1251_CR13","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/BF01948017","volume":"48","author":"A Evidente","year":"1992","unstructured":"Evidente A, Capretti P, Giordano FE, Surico G (1992) Identification and phytotoxicity of 3-nitropropionic acid produced in vitro by Melanconis thelebola. Experiment 48:1169\u20131172","journal-title":"Experiment"},{"issue":"3","key":"1251_CR14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1021\/np058128n","volume":"69","author":"AAL Gunatilaka","year":"2006","unstructured":"Gunatilaka AAL (2006) Natural products from plant-associated microorganisms: distribution, structural diversity, bioactivity, and implications of their occurrence. J Nat Prod 69(3):509\u2013526. doi: 10.1021\/np058128n","journal-title":"J Nat Prod"},{"key":"1251_CR15","volume-title":"Mitochondrial inhibitors and Neurodegenerative disorders","author":"BF Hamilton","year":"1999","unstructured":"Hamilton BF, Gould DH and Gustine DL (1999) History of 3-Nitropropionic acid: occurrence and role in human and animal disease. In: Sanberg PR, Nishino H and Borlongan CV Mitochondrial inhibitors and Neurodegenerative disorders, New Jersey, Human Press"},{"issue":"33","key":"1251_CR16","doi-asserted-by":"crossref","first-page":"6037","DOI":"10.1016\/0040-4039(94)88068-9","volume":"35","author":"WS Horn","year":"1994","unstructured":"Horn WS, Schwartz RE, Simmonds MSJ, Blaney WM (1994) Isolation and characterization of Phomodiol, a new antifungal from Phomopsis. Tetrahedron Lett 35(33):6037\u20136040. doi: 10.1016\/0040-4039(94)88068-9","journal-title":"Tetrahedron Lett"},{"issue":"14","key":"1251_CR17","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.1016\/0040-4020(95)00139-Y","volume":"51","author":"WS Horn","year":"1995","unstructured":"Horn WS, Simmonds MSJ, Schwartz RE, Blaney WM (1995) Phomopsichalasin, a novel antimicrobial agent from an endophytic Phomopsis sp. Tetrahedron 51(14):3969\u20133978. doi: 10.1016\/0040-4020(95)00139-Y","journal-title":"Tetrahedron"},{"issue":"4","key":"1251_CR18","doi-asserted-by":"crossref","first-page":"588","DOI":"10.2307\/3761152","volume":"88","author":"WS Horn","year":"1996","unstructured":"Horn WS, Simmonds MSJ, Schwartz RE, Blaney WM (1996) Variation in production of phomodiol and phomopsolide B by Phomopsis spp. Mycology 88(4):588\u2013595","journal-title":"Mycology"},{"key":"1251_CR19","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1021\/np010006h","volume":"64","author":"M Isaka","year":"2001","unstructured":"Isaka M, Jaturapat A, Rukseree K, Danwisetkanjana K, Tanticharoen M, Thebtaranonth Y (2001) Phomoxanthones A and B, novel xanthone dimmers from the endophytic fungus Phomopsis species. J Nat Prod 64:1015\u20131018","journal-title":"J Nat Prod"},{"key":"1251_CR20","first-page":"319","volume-title":"Phytotoxins and plant pathogenesis","author":"D Kenfield","year":"1989","unstructured":"Kenfield D, Bunkers G, Strobel GA, Sugawara F (1989) Fungal phytotoxins potential new herbicides. In: Graniti A, Durbin DR, Ballio A Phytotoxins and plant pathogenesis. Berlin, Springer, pp 319"},{"key":"1251_CR21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/10575639508043176","volume":"6","author":"K Krohn","year":"1995","unstructured":"Krohn K, Michel A, Roemer E, Floerke U, Aust HJ, Draeger S, Schultz B, Wray V (1995) Biologically active metabolites from fungi Phomosines A\u2013C. Three new biaryl ethers from Phomopsis sp. Nat Prod Lett 6:309\u2013314","journal-title":"Nat Prod Lett"},{"key":"1251_CR22","first-page":"142","volume-title":"O nim\u2014Azadirachta indica: natureza, usos m\u00faltiplos, produ\u00e7\u00e3o","author":"SS Martinez","year":"2002","unstructured":"Martinez SS (2002) O nim\u2014Azadirachta indica: natureza, usos m\u00faltiplos, produ\u00e7\u00e3o. Instituto Agron\u00f4mico do Paran\u00e1, Londrina, p 142"},{"key":"1251_CR23","doi-asserted-by":"crossref","unstructured":"Matos AP, Nebo L, Vieira PC, Fernandes JB, Silva MFG da (2009) Constituintes qu\u00edmicos e atividade inseticida dos extratos de frutos de Trichilia elegans e T. catigua (Meliaceae). Qu\u00edm Nova 32: (6) 1553\u20131556. doi: 10.1590\/S0100-40422009000600037","DOI":"10.1590\/S0100-40422009000600037"},{"issue":"1","key":"1251_CR24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0031-9422(00)80842-0","volume":"24","author":"M Nakatani","year":"1985","unstructured":"Nakatani M, Iwashita T, Naoki H, Hase T (1985) Structure of a limonoid antifeedant from Trichilia roka. Phytochemistry 24(1):195\u2013196. doi: 10.1016\/S0031-9422(00)80842-0","journal-title":"Phytochemistry"},{"issue":"2","key":"1251_CR25","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1590\/S1415-47572004000200021","volume":"27","author":"JA Pamphile","year":"2004","unstructured":"Pamphile JA, da Rocha CLMSC, Azevedo JL (2004) Co-transformation of a tropical maize endophytic isolate of Fusarium verticillioides (synonym F. moniliforme) with gusA and niA genes. Genet Mol Biol 27(2):253\u2013258. doi: 10.1590\/S1415-47572004000200021","journal-title":"Genet Mol Biol"},{"key":"1251_CR26","first-page":"62","volume":"29","author":"PAS Peixoto-Neto","year":"2002","unstructured":"Peixoto-Neto PAS, Azevedo JL, Ara\u00fajo WL (2002) Microrganismos endof\u00edticos. Biotec Ci\u00eanc e Desenv 29:62\u201376","journal-title":"Biotec Ci\u00eanc e Desenv"},{"key":"1251_CR27","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1574-695X.2006.00155.x","volume":"48","author":"S Phongpaichit","year":"2006","unstructured":"Phongpaichit S, Rungjindamai N, Rukachaisirikul V, Sakayaroj J (2006) Antimicrobial activity in cultures of endophytic fungi isolated from Garcinia species. FEMS Immunol Med Microbiol 48:367\u2013372. doi: 10.1111\/j.1574-695X.2006.00155.x","journal-title":"FEMS Immunol Med Microbiol"},{"key":"1251_CR28","doi-asserted-by":"crossref","first-page":"5085","DOI":"10.1016\/S0040-4020(00)00423-3","volume":"56","author":"MC Ram\u00edrez","year":"2000","unstructured":"Ram\u00edrez MC, Toscano RA, Arnason J, Omar S, Cerda-Garc\u00eda-Rojas CM, Mata R (2000) Structure, conformation and absolute configuration of new antifeedant dolabellanes from Trichilia trifolia. Tetrahedron 56:5085\u20135091. doi: 10.1016\/S0040-4020(00)00423-3","journal-title":"Tetrahedron"},{"issue":"3","key":"1251_CR29","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.4238\/2012.June.15.8","volume":"11","author":"SA Rhoden","year":"2012","unstructured":"Rhoden SA, Garcia A, Rubin-filho CJ, Azevedo JL, Pamphile JA (2012a) Phylogenetic diversity of endophytic leaf fungus isolates from the medicinal tree Trichilia elegans (Meliaceae). Genet Mol Res 11(3):2513\u20132522. doi: 10.4238\/2012.June.15.8","journal-title":"Genet Mol Res"},{"issue":"08","key":"1251_CR30","first-page":"57","volume":"02","author":"SA Rhoden","year":"2012","unstructured":"Rhoden SA, Garcia A, Bongiorno VA, Azevedo JL, Pamphile JA (2012b) Antimicrobial activity of crude extracts of endophytic fungi isolated from medicinal plant Trichilia elegans A Juss. J App Pharm Sci 02(08):57\u201359. doi: 10.7324\/JAPS.2012.2807","journal-title":"J App Pharm Sci"},{"key":"1251_CR31","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.phytochem.2007.09.006","volume":"68","author":"V Rukachaisirikul","year":"2008","unstructured":"Rukachaisirikul V, Sommart U, Phongpaichit S, Sakayaroj J, Kirtikara K (2008) Metabolites from the endophytic fungus Phomopsis sp. PSU-D15. Phytochemistry 68:783\u2013787. doi: 10.1016\/j.phytochem.2007.09.006","journal-title":"Phytochemistry"},{"key":"1251_CR32","volume-title":"Molecular cloning: a laboratory manual","author":"J Sambrook","year":"2001","unstructured":"Sambrook J, Russel LDW (2001) Molecular cloning: a laboratory manual, 3rd edn. Cold Spring Harbor Laboratory Press, New York","edition":"3"},{"key":"1251_CR33","unstructured":"SAS (2001) SAS Institute Inc., Cary, NC, USA"},{"key":"1251_CR34","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1017\/S0953756202006342","volume":"106","author":"B Schulz","year":"2002","unstructured":"Schulz B, Boyle C, Draeger S, R\u00f6mmert A, Krohn K (2002) Endophytic Fungi: a source of novel biologically active secondary metabolites. Mycol Res 106:996\u20131004. doi: 10.1017\/S0953756202006342","journal-title":"Mycol Res"},{"key":"1251_CR35","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1016\/j.phytochem.2004.06.035","volume":"65","author":"M Schwarz","year":"2004","unstructured":"Schwarz M, K\u00f6pcke B, Weber RWS, Sterner O, Anke H (2004) 3-Hydroxypropionic acid as a nematicidal principle in endophytic fungi. Phytochemistry 65:2239\u20132245. doi: 10.1016\/j.phytochem.2004.06.035","journal-title":"Phytochemistry"},{"issue":"6","key":"1251_CR36","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1590\/S0103-50532005000800029","volume":"16","author":"GH Silva","year":"2005","unstructured":"Silva GH, Teles HL, Trevisan HC, Bolzani VS, Young MCM, Pfenning LH, Eberlin MN, Haddad R, Costa-Neto CM, Ara\u00fajo AR (2005) New bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilis. J Braz Chem Soc 16(6):1463\u20131466. doi: 10.1590\/S0103-50532005000800029","journal-title":"J Braz Chem Soc"},{"issue":"2","key":"1251_CR37","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1590\/S0044-59672004000200006","volume":"34","author":"AQL Souza","year":"2004","unstructured":"Souza AQL, Souza AFD, Astolfi-Filho S, Bel\u00e9m-Pinheiro ML, Sarquis MIM, Pereira JO (2004) Atividade Antimicrobiana de fungos endof\u00edticos isolados de plantas t\u00f3xicas da Amaz\u00f4nia: Palicourea longiflora (aubl.) rich e Strychnos cogens bentham. Acta Amaz 34(2):185\u2013195","journal-title":"Acta Amaz"},{"issue":"2","key":"1251_CR38","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1021\/np030397v","volume":"67","author":"G Strobel","year":"2004","unstructured":"Strobel G, Daisy B, Castillo U, Harper J (2004) Natural products from endophytic microorganisms. J Nat Prod 67(2):257\u2013268. doi: 10.1021\/np030397v","journal-title":"J Nat Prod"},{"issue":"8","key":"1251_CR39","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1139\/v92-286","volume":"70","author":"YS Tsantrizos","year":"1992","unstructured":"Tsantrizos YS, Ogilvie KK, Watson AK (1992) Phytotoxic metabolites of Phomopsis convolvulus, a host-especific pathogen of field bindweed. Can J Chem 70(8):2276\u20132284. doi: 10.1139\/v92-286","journal-title":"Can J Chem"},{"key":"1251_CR40","doi-asserted-by":"crossref","unstructured":"Gomes-Figueiredo J, Pimentel IC, Vicente, VA, Pie MR, Kava-Cordeiro V, Galli-Terasawa L, Pereira JO, Souza AQL, Glienke C (2007) Bioprospecting highly diverse endophytic Pestalotiopsis spp. with antibacterial properties from Maytenus ilicifolia, a medicinal plant from Brazil. Can J Microbiol 53(10):1123\u20131132","DOI":"10.1139\/W07-078"},{"issue":"3","key":"1251_CR41","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1590\/S0100-40422003000300017","volume":"26","author":"C Viegas-junior","year":"2003","unstructured":"Viegas-junior C (2003) Terpenos com atividade inseticida: uma alternativa para o controle qu\u00edmico de insetos. Qu\u00edm nova 26(3):390\u2013400. doi: 10.1590\/S0100-40422003000300017","journal-title":"Qu\u00edm nova"},{"key":"1251_CR42","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1021\/np010020u","volume":"64","author":"MM Wagenaar","year":"2001","unstructured":"Wagenaar MM, Clardy J (2001) Dicerandrols, new antibiotic and cytotoxic dimer produced by the fungus Phomopsis longicolla isolated from an endangered mint. J Nat Prod 64:1006\u20131009. doi: 10.1021\/np010020u","journal-title":"J Nat Prod"},{"key":"1251_CR43","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1039\/b609472b","volume":"23","author":"HW Zhang","year":"2006","unstructured":"Zhang HW, Song YC, Tan RX (2006) Biology and chemistry of endophytes. Nat Prod Rep 23:753\u2013771. doi: 10.1039\/B609472B","journal-title":"Nat Prod Rep"}],"container-title":["World Journal of Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-013-1251-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11274-013-1251-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-013-1251-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T01:49:10Z","timestamp":1562550550000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11274-013-1251-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,8]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["1251"],"URL":"https:\/\/doi.org\/10.1007\/s11274-013-1251-2","relation":{},"ISSN":["0959-3993","1573-0972"],"issn-type":[{"value":"0959-3993","type":"print"},{"value":"1573-0972","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,8]]}}}