{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T22:00:21Z","timestamp":1790546421703,"version":"4.1.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003093","name":"Ministry of HIgher Education, Malaysia","doi-asserted-by":"crossref","award":["203\/CIPPT\/6711628"],"award-info":[{"award-number":["203\/CIPPT\/6711628"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003093","name":"Ministry of HIgher Education, Malaysia","doi-asserted-by":"crossref","award":["203\/CIPPT\/6711628"],"award-info":[{"award-number":["203\/CIPPT\/6711628"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Microbiol Biotechnol"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s11274-023-03540-4","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T14:41:29Z","timestamp":1676990489000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transcription start site mapping and small RNA profiling of Leptospira biflexa serovar Patoc"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9172-2487","authenticated-orcid":false,"given":"Hong-Leong","family":"Cheah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0626-175X","authenticated-orcid":false,"given":"Siti Aminah","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7652-7923","authenticated-orcid":false,"given":"Thean-Hock","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"3540_CR1","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3389\/fcimb.2018.00045","volume":"8","author":"H Adhikarla","year":"2018","unstructured":"Adhikarla H, Wunder EA, Mechaly AE et al (2018) Lvr, a signaling system that controls global gene regulation and virulence in pathogenic leptospira. Front Cell Infect Microbiol 8:45. https:\/\/doi.org\/10.3389\/fcimb.2018.00045","journal-title":"Front Cell Infect Microbiol"},{"key":"3540_CR2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/1471-2105-15-89","volume":"15","author":"F Amman","year":"2014","unstructured":"Amman F, Wolfinger MT, Lorenz R et al (2014) TSSAR: TSS annotation regime for dRNA-seq data. BMC Bioinform 15:89. https:\/\/doi.org\/10.1186\/1471-2105-15-89","journal-title":"BMC Bioinform"},{"key":"3540_CR3","unstructured":"Andrews S (2010) FastQC: a quality control tool for high throughput sequence data."},{"key":"3540_CR4","doi-asserted-by":"publisher","first-page":"W202","DOI":"10.1093\/nar\/gkp335","volume":"37","author":"TL Bailey","year":"2009","unstructured":"Bailey TL, Boden M, Buske FA et al (2009) MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res 37:W202\u2013W208. https:\/\/doi.org\/10.1093\/nar\/gkp335","journal-title":"Nucleic Acids Res"},{"key":"3540_CR5","doi-asserted-by":"publisher","first-page":"14560","DOI":"10.1073\/pnas.0603979103","volume":"103","author":"DM Bulach","year":"2006","unstructured":"Bulach DM, Zuerner RL, Wilson P et al (2006) Genome reduction in Leptospira borgpetersenii reflects limited transmission potential. Proc Natl Acad Sci USA 103:14560\u201314565. https:\/\/doi.org\/10.1073\/pnas.0603979103","journal-title":"Proc Natl Acad Sci USA"},{"key":"3540_CR6","doi-asserted-by":"publisher","first-page":"e1004004","DOI":"10.1371\/journal.ppat.1004004","volume":"10","author":"MJ Caimano","year":"2014","unstructured":"Caimano MJ, Sivasankaran SK, Allard A et al (2014) A model system for studying the transcriptomic and physiological changes associated with mammalian host-adaptation by Leptospira interrogans serovar copenhageni. PLoS Pathog 10:e1004004. https:\/\/doi.org\/10.1371\/journal.ppat.1004004","journal-title":"PLoS Pathog"},{"issue":"18","key":"3540_CR7","doi-asserted-by":"publisher","first-page":"e3757","DOI":"10.21769\/BioProtoc.3757","volume":"10","author":"R Cervantes-Rivera","year":"2020","unstructured":"Cervantes-Rivera R, Puhar A (2020) Whole-genome identification of transcriptional start sites by differential RNA-seq in bacteria. Bio Protoc 10(18):e3757. https:\/\/doi.org\/10.21769\/BioProtoc.3757","journal-title":"Bio Protoc"},{"key":"3540_CR8","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1080\/10409238.2018.1473330","volume":"53","author":"H-L Cheah","year":"2018","unstructured":"Cheah H-L, Raabe CA, Lee L-P et al (2018) Bacterial regulatory RNAs: complexity, function, and putative drug targeting. Crit Rev Biochem Mol 53:335\u2013355. https:\/\/doi.org\/10.1080\/10409238.2018.1473330","journal-title":"Crit Rev Biochem Mol"},{"key":"3540_CR9","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1186\/s12864-016-2539-z","volume":"17","author":"L Ettwiller","year":"2016","unstructured":"Ettwiller L, Buswell J, Yigit E, Schildkraut I (2016) A novel enrichment strategy reveals unprecedented number of novel transcription start sites at single base resolution in model prokaryote and the gut microbiome. BMC Genomics 17:199. https:\/\/doi.org\/10.1186\/s12864-016-2539-z","journal-title":"BMC Genomics"},{"key":"3540_CR10","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1093\/bioinformatics\/btw354","volume":"32","author":"P Ewels","year":"2016","unstructured":"Ewels P, Magnusson M, Lundin S, K\u00e4ller M (2016) MultiQC: summarize analysis results for multiple tools and samples in a single report. Bioinformatics 32:3047\u20133048. https:\/\/doi.org\/10.1093\/bioinformatics\/btw354","journal-title":"Bioinformatics"},{"key":"3540_CR11","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1111\/mmi.14831","volume":"116","author":"L Fule","year":"2021","unstructured":"Fule L, Halifa R, Fontana C et al (2021) Role of the major determinant of polar flagellation FlhG in the endoflagella-containing spirochete Leptospira. Mol Microbiol 116:1392\u20131406. https:\/\/doi.org\/10.1111\/mmi.14831","journal-title":"Mol Microbiol"},{"key":"3540_CR12","doi-asserted-by":"publisher","first-page":"12102","DOI":"10.1093\/nar\/gkaa966","volume":"48","author":"RA Gaultney","year":"2020","unstructured":"Gaultney RA, Vincent AT, Lorioux C et al (2020) 4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans. Nucleic Acids Res 48:12102\u201312115. https:\/\/doi.org\/10.1093\/nar\/gkaa966","journal-title":"Nucleic Acids Res"},{"key":"3540_CR13","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1515\/BC.2011.046","volume":"392","author":"J Georg","year":"2011","unstructured":"Georg J, Hess WR (2011) Regulatory RNAs in cyanobacteria: developmental decisions, stress responses and a plethora of chromosomally encoded cis-antisense RNAs. Biol Chem 392:291\u2013297. https:\/\/doi.org\/10.1515\/BC.2011.046","journal-title":"Biol Chem"},{"key":"3540_CR14","doi-asserted-by":"publisher","first-page":"e1009078","DOI":"10.1371\/journal.ppat.1009078","volume":"17","author":"AA Grassmann","year":"2021","unstructured":"Grassmann AA, Zavala-Alvarado C, Bettin EB et al (2021) The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans. PLoS Pathog 17:e1009078. https:\/\/doi.org\/10.1371\/journal.ppat.1009078","journal-title":"PLoS Pathog"},{"key":"3540_CR15","doi-asserted-by":"publisher","first-page":"e00042","DOI":"10.1128\/mSphere.00042-16","volume":"1","author":"G Iraola","year":"2016","unstructured":"Iraola G, Spangenberg L, Lopes Bastos B et al (2016) Transcriptome sequencing reveals wide expression reprogramming of basal and unknown genes in Leptospira biflexa biofilms. mSphere 1:e00042-e116. https:\/\/doi.org\/10.1128\/mSphere.00042-16","journal-title":"mSphere"},{"key":"3540_CR16","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1111\/j.1365-2958.2007.05688.x","volume":"64","author":"M Kawano","year":"2007","unstructured":"Kawano M, Aravind L, Storz G (2007) An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin. Mol Microbiol 64:738\u2013754. https:\/\/doi.org\/10.1111\/j.1365-2958.2007.05688.x","journal-title":"Mol Microbiol"},{"key":"3540_CR17","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"B Langmead","year":"2012","unstructured":"Langmead B, Salzberg SL (2012) Fast gapped-read alignment with Bowtie 2. Nat Methods 9:357\u2013359. https:\/\/doi.org\/10.1038\/nmeth.1923","journal-title":"Nat Methods"},{"key":"3540_CR18","doi-asserted-by":"publisher","first-page":"723","DOI":"10.3390\/microorganisms10040723","volume":"10","author":"LE Leiva","year":"2022","unstructured":"Leiva LE, Katz A (2022) Regulation of leaderless mRNA translation in bacteria. Microorganisms 10:723. https:\/\/doi.org\/10.3390\/microorganisms10040723","journal-title":"Microorganisms"},{"key":"3540_CR19","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.mib.2007.03.005","volume":"10","author":"J Livny","year":"2007","unstructured":"Livny J, Waldor MK (2007) Identification of small RNAs in diverse bacterial species. Curr Opin Microbiol 10:96\u2013101","journal-title":"Curr Opin Microbiol"},{"key":"3540_CR20","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1501363","author":"V Llor\u00e9ns-Rico","year":"2016","unstructured":"Llor\u00e9ns-Rico V, Cano J, Kamminga T et al (2016) Bacterial antisense RNAs are mainly the product of transcriptional noise. Sci Adv. https:\/\/doi.org\/10.1126\/sciadv.1501363","journal-title":"Sci Adv"},{"key":"3540_CR21","doi-asserted-by":"publisher","first-page":"4850","DOI":"10.1128\/IAI.00435-10","volume":"78","author":"M Lo","year":"2010","unstructured":"Lo M, Murray GL, Khoo CA et al (2010) Transcriptional response of Leptospira interrogans to iron limitation and characterization of a PerR homolog. Infect Immun 78:4850\u20134859. https:\/\/doi.org\/10.1128\/IAI.00435-10","journal-title":"Infect Immun"},{"key":"3540_CR22","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1016\/j.cell.2009.08.046","volume":"139","author":"E Loh","year":"2009","unstructured":"Loh E, Dussurget O, Gripenland J et al (2009) A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes. Cell 139:770\u2013779. https:\/\/doi.org\/10.1016\/j.cell.2009.08.046","journal-title":"Cell"},{"key":"3540_CR23","doi-asserted-by":"publisher","first-page":"10","DOI":"10.14806\/ej.17.1.200","volume":"17","author":"M Martin","year":"2011","unstructured":"Martin M (2011) Cutadapt removes adapter sequences from high-throughput sequencing reads. Embnet j 17:10. https:\/\/doi.org\/10.14806\/ej.17.1.200","journal-title":"Embnet j"},{"key":"3540_CR24","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1038\/s41467-022-28871-y","volume":"13","author":"B Martinez","year":"2022","unstructured":"Martinez B, Bharati BK, Epshtein V, Nudler E (2022) Pervasive transcription-coupled DNA repair in E. coli. Nat Commun 13:1702. https:\/\/doi.org\/10.1038\/s41467-022-28871-y","journal-title":"Nat Commun"},{"key":"3540_CR25","doi-asserted-by":"publisher","first-page":"2864","DOI":"10.1128\/IAI.01619-06","volume":"75","author":"J Matsunaga","year":"2007","unstructured":"Matsunaga J, Lo M, Bulach DM et al (2007) Response of Leptospira interrogans to physiologic osmolarity: relevance in signaling the environment-to-host transition. Infect Immun 75:2864\u20132874. https:\/\/doi.org\/10.1128\/IAI.01619-06","journal-title":"Infect Immun"},{"key":"3540_CR26","doi-asserted-by":"publisher","first-page":"e140","DOI":"10.1093\/nar\/gkt444","volume":"41","author":"R McClure","year":"2013","unstructured":"McClure R, Balasubramanian D, Sun Y et al (2013) Computational analysis of bacterial RNA-Seq data. Nucleic Acids Res 41:e140\u2013e140. https:\/\/doi.org\/10.1093\/nar\/gkt444","journal-title":"Nucleic Acids Res"},{"key":"3540_CR27","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.mib.2015.01.013","volume":"24","author":"M Miyakoshi","year":"2015","unstructured":"Miyakoshi M, Chao Y, Vogel J (2015) Regulatory small RNAs from the 3\u2019 regions of bacterial mRNAs. Curr Opin Microbiol 24:132\u2013139. https:\/\/doi.org\/10.1016\/j.mib.2015.01.013","journal-title":"Curr Opin Microbiol"},{"key":"3540_CR28","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.tibs.2012.07.007","volume":"37","author":"I Moll","year":"2012","unstructured":"Moll I, Engelberg-Kulka H (2012) Selective translation during stress in Escherichia coli. Trends Biochem Sci 37:493\u2013498. https:\/\/doi.org\/10.1016\/j.tibs.2012.07.007","journal-title":"Trends Biochem Sci"},{"key":"3540_CR29","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1093\/bioinformatics\/btt509","volume":"29","author":"EP Nawrocki","year":"2013","unstructured":"Nawrocki EP, Eddy SR (2013) Infernal 1.1: 100-fold faster RNA homology searches. Bioinform 29:2933\u20132935. https:\/\/doi.org\/10.1093\/bioinformatics\/btt509","journal-title":"Bioinform"},{"key":"3540_CR30","doi-asserted-by":"publisher","first-page":"D130","DOI":"10.1093\/nar\/gku1063","volume":"43","author":"EP Nawrocki","year":"2015","unstructured":"Nawrocki EP, Burge SW, Bateman A et al (2015) Rfam 12.0: updates to the RNA families database. Nucleic Acids Res 43:D130\u2013D137. https:\/\/doi.org\/10.1093\/nar\/gku1063","journal-title":"Nucleic Acids Res"},{"key":"3540_CR31","doi-asserted-by":"publisher","first-page":"9","DOI":"10.4161\/trns.2.1.13511","volume":"2","author":"AC Palmer","year":"2011","unstructured":"Palmer AC, Barry Egan J, Shearwin KE (2011) Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors. Transcription 2:9\u201314. https:\/\/doi.org\/10.4161\/trns.2.1.13511","journal-title":"Transcription"},{"key":"3540_CR32","doi-asserted-by":"publisher","first-page":"6091","DOI":"10.1128\/AEM.01619-14","volume":"80","author":"H P\u011btro\u0161ov\u00e1","year":"2014","unstructured":"P\u011btro\u0161ov\u00e1 H, Picardeau M (2014) Screening of a Leptospira biflexa mutant library to identify genes involved in ethidium bromide tolerance. Appl Environ Microbiol 80:6091\u20136103. https:\/\/doi.org\/10.1128\/AEM.01619-14","journal-title":"Appl Environ Microbiol"},{"key":"3540_CR33","doi-asserted-by":"publisher","first-page":"e1607","DOI":"10.1371\/journal.pone.0001607","volume":"3","author":"M Picardeau","year":"2008","unstructured":"Picardeau M, Bulach DM, Bouchier C et al (2008) Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PLoS ONE 3:e1607. https:\/\/doi.org\/10.1371\/journal.pone.0001607","journal-title":"PLoS ONE"},{"key":"3540_CR34","doi-asserted-by":"publisher","first-page":"e0009320","DOI":"10.1371\/journal.pntd.0009320","volume":"15","author":"EJ Putz","year":"2021","unstructured":"Putz EJ, Sivasankaran SK, Fernandes LGV et al (2021) Distinct transcriptional profiles of Leptospira borgpetersenii serovar Hardjo strains JB197 and HB203 cultured at different temperatures. PLoS Negl Trop Dis 15:e0009320. https:\/\/doi.org\/10.1371\/journal.pntd.0009320","journal-title":"PLoS Negl Trop Dis"},{"key":"3540_CR35","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/1471-2180-6-51","volume":"6","author":"J-H Qin","year":"2006","unstructured":"Qin J-H, Sheng Y-Y, Zhang Z-M et al (2006) Genome-wide transcriptional analysis of temperature shift in L. interrogans serovar lai strain 56601. BMC Microbiol 6:51. https:\/\/doi.org\/10.1186\/1471-2180-6-51","journal-title":"BMC Microbiol"},{"key":"3540_CR36","doi-asserted-by":"publisher","first-page":"e00156","DOI":"10.1128\/mBio.00156-12","volume":"3","author":"R Raghavan","year":"2012","unstructured":"Raghavan R, Sloan DB, Ochman H (2012) Antisense transcription is pervasive but rarely conserved in enteric bacteria. Mbio 3:e00156-e212. https:\/\/doi.org\/10.1128\/mBio.00156-12","journal-title":"Mbio"},{"key":"3540_CR37","doi-asserted-by":"publisher","first-page":"636","DOI":"10.3389\/fgene.2018.00636","volume":"9","author":"MS Rao","year":"2019","unstructured":"Rao MS, Van Vleet TR, Ciurlionis R et al (2019) Comparison of RNA-seq and microarray gene expression platforms for the toxicogenomic evaluation of liver from short-term rat toxicity studies. Front Genet 9:636. https:\/\/doi.org\/10.3389\/fgene.2018.00636","journal-title":"Front Genet"},{"key":"3540_CR38","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.mib.2014.06.010","volume":"19","author":"CM Sharma","year":"2014","unstructured":"Sharma CM, Vogel J (2014) Differential RNA-seq: the approach behind and the biological insight gained. Curr Opin Microbiol 19:97\u2013105. https:\/\/doi.org\/10.1016\/j.mib.2014.06.010","journal-title":"Curr Opin Microbiol"},{"key":"3540_CR39","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1038\/nature08756","volume":"464","author":"CM Sharma","year":"2010","unstructured":"Sharma CM, Hoffmann S, Darfeuille F et al (2010) The primary transcriptome of the major human pathogen Helicobacter pylori. Nature 464:250\u2013255. https:\/\/doi.org\/10.1038\/nature08756","journal-title":"Nature"},{"key":"3540_CR40","doi-asserted-by":"publisher","first-page":"e1005641","DOI":"10.1371\/journal.pgen.1005641","volume":"11","author":"SS Shell","year":"2015","unstructured":"Shell SS, Wang J, Lapierre P et al (2015) Leaderless transcripts and small proteins are common features of the mycobacterial translational landscape. PLoS Genet 11:e1005641. https:\/\/doi.org\/10.1371\/journal.pgen.1005641","journal-title":"PLoS Genet"},{"key":"3540_CR41","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3390\/bioengineering8050059","volume":"8","author":"A Telatin","year":"2021","unstructured":"Telatin A, Fariselli P, Birolo G (2021) SeqFu: a suite of utilities for the robust and reproducible manipulation of sequence files. Bioengineering 8:59. https:\/\/doi.org\/10.3390\/bioengineering8050059","journal-title":"Bioengineering"},{"key":"3540_CR42","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1128\/JB.02096-14","volume":"197","author":"MK Thomason","year":"2015","unstructured":"Thomason MK, Bischler T, Eisenbart SK et al (2015) Global transcriptional start site mapping using differential RNA sequencing reveals novel antisense RNAs in Escherichia coli. J Bacteriol 197:18\u201328. https:\/\/doi.org\/10.1128\/JB.02096-14","journal-title":"J Bacteriol"},{"key":"3540_CR43","doi-asserted-by":"publisher","first-page":"4809","DOI":"10.1093\/nar\/gkm487","volume":"35","author":"Z Weinberg","year":"2007","unstructured":"Weinberg Z, Barrick JE, Yao Z et al (2007) Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline. Nucleic Acids Res 35:4809\u20134819. https:\/\/doi.org\/10.1093\/nar\/gkm487","journal-title":"Nucleic Acids Res"},{"key":"3540_CR44","doi-asserted-by":"publisher","first-page":"e857","DOI":"10.1371\/journal.pntd.0000857","volume":"4","author":"F Xue","year":"2010","unstructured":"Xue F, Dong H, Wu J et al (2010) Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. PLoS Negl Trop Dis 4:e857. https:\/\/doi.org\/10.1371\/journal.pntd.0000857","journal-title":"PLoS Negl Trop Dis"},{"key":"3540_CR45","doi-asserted-by":"publisher","first-page":"e1008904","DOI":"10.1371\/journal.ppat.1008904","volume":"16","author":"C Zavala-Alvarado","year":"2020","unstructured":"Zavala-Alvarado C, Sismeiro O, Legendre R et al (2020) The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress. PLoS Pathog 16:e1008904. https:\/\/doi.org\/10.1371\/journal.ppat.1008904","journal-title":"PLoS Pathog"},{"key":"3540_CR46","doi-asserted-by":"publisher","first-page":"e1009087","DOI":"10.1371\/journal.ppat.1009087","volume":"17","author":"C Zavala-Alvarado","year":"2021","unstructured":"Zavala-Alvarado C, G. Huete S, Vincent AT, et al (2021) The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence. PLoS Pathog 17:e1009087. https:\/\/doi.org\/10.1371\/journal.ppat.1009087","journal-title":"PLoS Pathog"},{"key":"3540_CR47","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00010","author":"A Zhukova","year":"2017","unstructured":"Zhukova A, Fernandes LG, Hugon P et al (2017) Genome-wide transcriptional start site mapping and sRNA identification in the pathogen Leptospira interrogans. Front Cell Infect Microbiol. https:\/\/doi.org\/10.3389\/fcimb.2017.00010","journal-title":"Front Cell Infect Microbiol"}],"container-title":["World Journal of Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-023-03540-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11274-023-03540-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-023-03540-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T17:56:18Z","timestamp":1679853378000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11274-023-03540-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,21]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["3540"],"URL":"https:\/\/doi.org\/10.1007\/s11274-023-03540-4","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-2224410\/v1","asserted-by":"object"}]},"ISSN":["0959-3993","1573-0972"],"issn-type":[{"value":"0959-3993","type":"print"},{"value":"1573-0972","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,21]]},"assertion":[{"value":"1 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no potential conflict of interest relating to the article\u2019s research, authorship, and publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"104"}}