{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:15:23Z","timestamp":1782792923284,"version":"3.54.5"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation","doi-asserted-by":"crossref","award":["32201933"],"award-info":[{"award-number":["32201933"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Department of Science and Technolgoy, China","award":["2018YFE0108400"],"award-info":[{"award-number":["2018YFE0108400"]}]},{"name":"National Department of Science and Technolgoy, China","award":["2018YFE0108400"],"award-info":[{"award-number":["2018YFE0108400"]}]},{"name":"National Department of Science and Technolgoy, China","award":["2018YFE0108400"],"award-info":[{"award-number":["2018YFE0108400"]}]},{"name":"National Department of Science and Technolgoy, China","award":["2018YFE0108400"],"award-info":[{"award-number":["2018YFE0108400"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Microbiol Biotechnol"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s11274-024-03945-9","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T01:03:04Z","timestamp":1710378184000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Anti-inflammatory effect of lignans from flaxseed after fermentation by lactiplantibacillus plantarum SCB0151 in vitro"],"prefix":"10.1007","volume":"40","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcheng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"3945_CR32","doi-asserted-by":"publisher","first-page":"173631","DOI":"10.1016\/j.ejphar.2020.173631","volume":"889","author":"AM Abdel-Aziz","year":"2020","unstructured":"Abdel-Aziz AM, Gamal El-Tahawy NF, Salah Abdel Haleem MA, Mohammed MM, Ali AI, Ibrahim YF (2020) Amelioration of testosterone-induced benign prostatic hyperplasia using febuxostat in rats: the role of VEGF\/TGF\u03b2 and iNOS\/COX-2. Eur J Pharmacol 889:173631. https:\/\/doi.org\/10.1016\/j.ejphar.2020.173631","journal-title":"Eur J Pharmacol"},{"key":"3945_CR33","doi-asserted-by":"publisher","first-page":"155394","DOI":"10.1016\/j.cyto.2020.155394","volume":"138","author":"K Amirshahrokhi","year":"2021","unstructured":"Amirshahrokhi K, Zohouri A (2021) Carvedilol prevents pancreatic \u03b2-cell damage and the development of type 1 diabetes in mice by the inhibition of proinflammatory cytokines, NF-\u03baB, COX-2, iNOS and oxidative stress. Cytokine 138:155394. https:\/\/doi.org\/10.1016\/j.cyto.2020.155394","journal-title":"Cytokine"},{"key":"3945_CR15","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.jff.2017.08.015","volume":"37","author":"D Bravo","year":"2017","unstructured":"Bravo D, Peirot\u00e9n \u00c1, \u00e1lvarez I, Landete JM (2017) Phytoestrogen metabolism by lactic acid bacteria: Enterolignan production by Lactobacillus salivarius and Lactobacillus gasseri strains. J Funct Foods 37:373\u2013378. https:\/\/doi.org\/10.1016\/j.jff.2017.08.015","journal-title":"J Funct Foods"},{"issue":"1","key":"3945_CR21","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3390\/fermentation7010022","volume":"7","author":"NS Brizuela","year":"2021","unstructured":"Brizuela NS, Arnez-Arancibia M, Semorile L, Pozo-Bay\u00f3n M\u00c1, Bravo-Ferrada BM, Tymczyszyn EE (2021) \u03b2-Glucosidase activity of Lactiplantibacillus Plantarum UNQLp 11 in different malolactic fermentations conditions: Effect of pH and ethanol content. Fermentation 7(1):22. https:\/\/doi.org\/10.3390\/fermentation7010022","journal-title":"Fermentation"},{"issue":"3","key":"3945_CR4","doi-asserted-by":"publisher","first-page":"534","DOI":"10.3390\/foods10030534","volume":"10","author":"J Bujok","year":"2021","unstructured":"Bujok J, Mi\u015bta D, Wincewicz E, Kr\u00f3liczewska B, Dzimira S, |uk M (2021) Atherosclerosis Development and aortic contractility in hypercholesterolemic rabbits supplemented with two different flaxseed varieties. Foods 10(3):534. https:\/\/doi.org\/10.3390\/foods10030534","journal-title":"Foods"},{"key":"3945_CR19","doi-asserted-by":"publisher","first-page":"153334","DOI":"10.1016\/j.phymed.2020.153334","volume":"79","author":"J Chen","year":"2020","unstructured":"Chen J, Qiu S, Kim JT, Cho JS, Moon JH, Zhou Y, Auh J, Lee HJ (2020) Garcinone C suppresses colon tumorigenesis through the gli1-dependent hedgehog signaling pathway. Phytomedicine 79:153334. https:\/\/doi.org\/10.1016\/j.phymed.2020.153334","journal-title":"Phytomedicine"},{"issue":"5298","key":"3945_CR3","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1126\/science.275.5298.362","volume":"275","author":"LB Davin","year":"1997","unstructured":"Davin LB, Wang H, Crowell AL, Bedgar DL, Martin DM, Sarkanen S, Lewis NG (1997) Stereoselective Bimolecular Phenoxy Radical Coupling by an Auxiliary (Dirigent) protein without an active Center. Science 275(5298):362\u2013367. https:\/\/doi.org\/10.1126\/science.275.5298.362","journal-title":"Science"},{"key":"3945_CR7","doi-asserted-by":"publisher","first-page":"110488","DOI":"10.1016\/j.foodres.2021.110488","volume":"147","author":"A De La Ruiz","year":"2021","unstructured":"De La Ruiz A, Peirot\u00e9n \u00c1, Langa S, \u00e1lvarez I, Arqu\u00e9s JL, Landete JM (2021) Metabolism of flavonoids and lignans by lactobacilli and bifidobacteria strains improves the nutritional properties of flaxseed-enriched beverages. Food Res Int 147:110488. https:\/\/doi.org\/10.1016\/j.foodres.2021.110488","journal-title":"Food Res Int"},{"issue":"2","key":"3945_CR5","doi-asserted-by":"publisher","first-page":"68","DOI":"10.3390\/ph12020068","volume":"12","author":"SF De Silva","year":"2019","unstructured":"De Silva SF, Alcorn J (2019) Flaxseed Lignans as important Dietary polyphenols for Cancer Prevention and Treatment: Chemistry, Pharmacokinetics, and molecular targets. Pharmaceuticals 12(2):68. https:\/\/doi.org\/10.3390\/ph12020068","journal-title":"Pharmaceuticals"},{"key":"3945_CR9","doi-asserted-by":"publisher","first-page":"109368","DOI":"10.1016\/j.jnutbio.2023.109368","volume":"118","author":"EK Farhat","year":"2023","unstructured":"Farhat EK, Sher EK, D\u017eidi\u0107-Krivi\u0107 A, Banjari I, Sher F (2023) Functional biotransformation of phytoestrogens by gut microbiota with impact on cancer treatment. J Nutr Biochem 118:109368. https:\/\/doi.org\/10.1016\/j.jnutbio.2023.109368","journal-title":"J Nutr Biochem"},{"key":"3945_CR10","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.jff.2017.06.038","volume":"35","author":"D Garc\u00eda-Mateos","year":"2017","unstructured":"Garc\u00eda-Mateos D, Garc\u00eda-Villalba R, Mara\u00f1\u00f3n JA, Esp\u00edn JC, Merino G, \u00e1lvarez AI (2017) The breast Cancer resistance protein (BCRP\/ABCG2) influences the levels of enterolignans and their metabolites in plasma, milk and mammary gland. J Funct Foods 35:648\u2013654. https:\/\/doi.org\/10.1016\/j.jff.2017.06.038","journal-title":"J Funct Foods"},{"key":"3945_CR16","doi-asserted-by":"publisher","unstructured":"Gaya P, Peirot\u00e9n \u00c1, Medina M, Landete JM (2017) Bifidobacterium adolescentis INIA P784: the first probiotic bacterium capable of producing enterodiol from lignan extracts. J Funct Foods 29:269\u2013274. https:\/\/doi.org\/10.1016\/j.jff.2016.12.044","DOI":"10.1016\/j.jff.2016.12.044"},{"key":"3945_CR29","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.aninu.2021.06.009","volume":"8","author":"R Hu","year":"2022","unstructured":"Hu R, Wu S, Li B, Tan J, Yan J, Wang Y, Tang Z, Liu M, Fu C, Zhang H, He J (2022) Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets. Anim Nutr 8:144\u2013152. https:\/\/doi.org\/10.1016\/j.aninu.2021.06.009","journal-title":"Anim Nutr"},{"issue":"2","key":"3945_CR17","doi-asserted-by":"publisher","first-page":"202","DOI":"10.7845\/kjm.2016.5049","volume":"52","author":"CE Hwang","year":"2016","unstructured":"Hwang CE, Haque MA, Lee JH, Ahn MJ, Lee HY, Lee BW, Lee Y, Lee C, Kim BJ, Park J, Sim E, Lee DH, Ko JM, Kim HT, Cho KM (2016) Changes in phytoestrogen contents and antioxidant activities during fermentation of soybean-powder milks prepared from different soybean cultivars by lactobacillus plantarum p1201. Korean J Microbiol 52(2):202\u2013211. https:\/\/doi.org\/10.7845\/kjm.2016.5049","journal-title":"Korean J Microbiol"},{"issue":"Suppl 1","key":"3945_CR11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.22074\/cellj.2017.4705","volume":"19","author":"D Ilbeigi","year":"2017","unstructured":"Ilbeigi D, Nourbakhsh M, Khaghani S, Einollahi N, Kheiripour N, Gholinejad Z, Alaee M, Saberian M (2017) Enterolactone reduces telomerase activity and the level of its catalytic subunit in breast cancer cells. Cell J 19(Suppl 1):7. https:\/\/doi.org\/10.22074\/cellj.2017.4705","journal-title":"Cell J"},{"key":"3945_CR27","doi-asserted-by":"publisher","first-page":"6587","DOI":"10.1007\/s00253-020-10667-z","volume":"104","author":"Y Ji","year":"2020","unstructured":"Ji Y, Li B, Qiao M, Li J, Xu H, Zhang L, Zhang X (2020) Advances on the in vivo and in vitro glycosylations of flavonoids. Appl Microbiol Biotech 104:6587\u20136600. https:\/\/doi.org\/10.1007\/s00253-020-10667-z","journal-title":"Appl Microbiol Biotech"},{"issue":"12","key":"3945_CR30","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/jfbc.13505","volume":"44","author":"RB Kassab","year":"2020","unstructured":"Kassab RB, Lokman MS, Daabo HMA, Gaber DA, Habotta OA, Hafez MM, Zhery AS, Moneim AEA, Fouda MS (2020) Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium-induced oxidative challenge, inflammation, and apoptosis in rats. J Food Biochem 44(12):12. https:\/\/doi.org\/10.1111\/jfbc.13505","journal-title":"J Food Biochem"},{"issue":"22","key":"3945_CR13","doi-asserted-by":"publisher","first-page":"5967","DOI":"10.1080\/10408398.2022.2026871","volume":"63","author":"D Li","year":"2023","unstructured":"Li D, Luo F, Guo T, Han S, Wang H, Lin Q (2023a) Targeting NF-\u03baB pathway by dietary lignans in inflammation: expanding roles of gut microbiota and metabolites. Crit Rev Food Sci 63(22):5967\u20135983. https:\/\/doi.org\/10.1080\/10408398.2022.2026871","journal-title":"Crit Rev Food Sci"},{"key":"3945_CR18","doi-asserted-by":"publisher","first-page":"102531","DOI":"10.1016\/j.fbio.2023.102531","volume":"53","author":"J Li","year":"2023","unstructured":"Li J, Zeng C, Huang Q, Zheng M, Chen J, Ma D (2023b) Control release of \u03b1-mangostin by a novel dual-polysaccharides delivery system for colitis treatment under simulated gastrointestinal conditions. Food Biosci 53:102531. https:\/\/doi.org\/10.1016\/j.fbio.2023.102531","journal-title":"Food Biosci"},{"issue":"1","key":"3945_CR12","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s13048-017-0346-z","volume":"10","author":"H Liu","year":"2017","unstructured":"Liu H, Liu J, Wang S, Zeng Z, Li T, Liu Y, Mastriani E, Li Q, Bao H, Zhou Y, Wang X, Hu S, Gao S, Qi Y, Shen Z, Wang H, Yu M, Gao T, Johnston RN, Liu S (2017) Enterolactone has stronger effects than enterodiol on ovarian cancer. J Ovarian Res 10(1):49. https:\/\/doi.org\/10.1186\/s13048-017-0346-z","journal-title":"J Ovarian Res"},{"issue":"2","key":"3945_CR25","doi-asserted-by":"publisher","first-page":"62","DOI":"10.3390\/md16020062","volume":"16","author":"H Liu","year":"2018","unstructured":"Liu H, Chen B, de Souza F, Liu L (2018) A comparative study on asymmetric reduction of Ketones using the growing and resting cells of Marine-Derived Fungi. Mar Drugs 16(2):62. https:\/\/doi.org\/10.3390\/md16020062","journal-title":"Mar Drugs"},{"issue":"3","key":"3945_CR31","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.nefroe.2020.06.017","volume":"40","author":"S Mozaffari Godarzi","year":"2020","unstructured":"Mozaffari Godarzi S, Valizade Gorji A, Gholizadeh B, Mard SA, Mansouri E (2020) Antioxidant effect of p-coumaric acid on interleukin 1-\u03b2 and tumor necrosis factor-\u03b1 in rats with renal ischemic reperfusion. Nefrolog\u00eda (English Edition) 40(3):311\u2013319. https:\/\/doi.org\/10.1016\/j.nefroe.2020.06.017","journal-title":"Nefrolog\u00eda (English Edition)"},{"key":"3945_CR8","doi-asserted-by":"publisher","unstructured":"Mueed A, Ibrahim M, Shibli S, Madjirebaye P, Deng Z, Jahangir M (2022) The fate of flaxseed-lignans after oral administration: a comprehensive review on its bioavailability, pharmacokinetics, and food design strategies for optimal application. Crit Rev Food Sci 1\u201319. https:\/\/doi.org\/10.1080\/10408398.2022.2140643","DOI":"10.1080\/10408398.2022.2140643"},{"issue":"5","key":"3945_CR6","doi-asserted-by":"publisher","first-page":"2286","DOI":"10.1039\/d2fo02208g","volume":"14","author":"A Mueed","year":"2023","unstructured":"Mueed A, Deng Z, Korma SA, Shibli S, Jahangir M (2023) Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives. Food Funct 14(5):2286\u20132303. https:\/\/doi.org\/10.1039\/d2fo02208g","journal-title":"Food Funct"},{"key":"3945_CR14","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.ijfoodmicro.2018.08.028","volume":"289","author":"\u00c1 Peirot\u00e9n","year":"2019","unstructured":"Peirot\u00e9n \u00c1, Gaya P, \u00e1lvarez I, Bravo D, Landete JM (2019) Influence of different lignan compounds on enterolignan production by Bifidobacterium and Lactobacillus strains. Int J Food Microbiol 289:17\u201323. https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2018.08.028","journal-title":"Int J Food Microbiol"},{"issue":"1","key":"3945_CR24","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00253-011-3338-8","volume":"92","author":"L Roncaglia","year":"2011","unstructured":"Roncaglia L, Amaretti A, Raimondi S, Leonardi A, Rossi M (2011) Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside. Appl Microbiol Biot 92(1):159\u2013168. https:\/\/doi.org\/10.1007\/s00253-011-3338-8","journal-title":"Appl Microbiol Biot"},{"issue":"S1","key":"3945_CR20","doi-asserted-by":"publisher","first-page":"S45","DOI":"10.1079\/BJN2002796","volume":"89","author":"I Rowland","year":"2003","unstructured":"Rowland I, Faughnan M, Hoey L, W\u00e4h\u00e4l\u00e4 K, Williamson G, Cassidy A (2003) Bioavailability of phyto-oestrogens. Brit J Nutr 89(S1):S45\u2013S58. https:\/\/doi.org\/10.1079\/BJN2002796","journal-title":"Brit J Nutr"},{"issue":"3","key":"3945_CR26","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1039\/C3FO60402K","volume":"5","author":"KDR Setchell","year":"2014","unstructured":"Setchell KDR, Brown NM, Zimmer-Nechemias L, Wolfe B, Jha P, Heubi JE (2014) Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans. Food Funct 5(3):491\u2013501. https:\/\/doi.org\/10.1039\/C3FO60402K","journal-title":"Food Funct"},{"issue":"3","key":"3945_CR1","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1541-4337.2009.00105.x","volume":"9","author":"A Tour\u00e9","year":"2010","unstructured":"Tour\u00e9 A, Xueming X (2010) Flaxseed lignans: source, biosynthesis, metabolism, antioxidant Activity, Bio-active Components, and Health benefits. Compr Rev Food Sci F 9(3):261\u2013269. https:\/\/doi.org\/10.1111\/j.1541-4337.2009.00105.x","journal-title":"Compr Rev Food Sci F"},{"key":"3945_CR23","doi-asserted-by":"publisher","first-page":"112219","DOI":"10.1016\/j.indcrop.2020.112219","volume":"147","author":"H Wang","year":"2020","unstructured":"Wang H, Guo X, Wu Y, Wang Y, Liu RH, Chen L, Liang Y, Qiu C (2020) Dynamic changes of phytochemical profiles identified key points of flaxseed capsule maturation for lignan accumulation. Ind Crop Prod 147:112219. https:\/\/doi.org\/10.1016\/j.indcrop.2020.112219","journal-title":"Ind Crop Prod"},{"issue":"6","key":"3945_CR2","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1021\/acs.jnatprod.1c00335","volume":"84","author":"X Yang","year":"2021","unstructured":"Yang X, Guo Y, Tse TJ, Purdy SK, Mustafa R, Shen J, Alcorn J, Reaney MJT (2021) Oral pharmacokinetics of enriched Secoisolariciresinol Diglucoside and its polymer in rats. J Nat Prod 84(6):1816\u20131822. https:\/\/doi.org\/10.1021\/acs.jnatprod.1c00335","journal-title":"J Nat Prod"},{"issue":"18","key":"3945_CR28","doi-asserted-by":"publisher","first-page":"7199","DOI":"10.1039\/d1gc01928g","volume":"23","author":"L Yu","year":"2021","unstructured":"Yu L, Bulone V (2021) De-glycosylation and enhanced bioactivity of flavonoids from apple pomace during extraction with deep eutectic solvents. Green Chem 23(18):7199\u20137209. https:\/\/doi.org\/10.1039\/d1gc01928g","journal-title":"Green Chem"}],"container-title":["World Journal of Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-024-03945-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11274-024-03945-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-024-03945-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T09:16:12Z","timestamp":1712394972000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11274-024-03945-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,14]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["3945"],"URL":"https:\/\/doi.org\/10.1007\/s11274-024-03945-9","relation":{},"ISSN":["0959-3993","1573-0972"],"issn-type":[{"value":"0959-3993","type":"print"},{"value":"1573-0972","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,14]]},"assertion":[{"value":"1 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there are no conflicts of interest. All authors agree to publish.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"134"}}