{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:44:05Z","timestamp":1771019045804,"version":"3.50.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Microbiol Biotechnol"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s11274-025-04330-w","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T01:05:00Z","timestamp":1746407100000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Physiological and transcriptomic responses of the microalga Isochrysis galbana during exposure to Hg(II) stress"],"prefix":"10.1007","volume":"41","author":[{"given":"Linlin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinfeng","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linke","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"4330_CR1","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.aquatox.2019.02.021","volume":"210","author":"AC Almeida","year":"2019","unstructured":"Almeida AC, Gomes T, Langford K, Thomas KV, Tollefsen KE (2019) Oxidative stress potential of the herbicides Bifenox and Metribuzin in the microalgae Chlamydomonas reinhardtii. Aquat Toxicol 210:117\u2013128. https:\/\/doi.org\/10.1016\/j.aquatox.2019.02.021","journal-title":"Aquat Toxicol"},{"issue":"1","key":"4330_CR2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.tim.2022.06.004","volume":"31","author":"N Ashraf","year":"2022","unstructured":"Ashraf N, Ahmad F, Lu Y (2022) Synergy between microalgae and Microbiome in polluted waters. Trends Microbiol 31(1):9\u201321. https:\/\/doi.org\/10.1016\/j.tim.2022.06.004","journal-title":"Trends Microbiol"},{"issue":"13","key":"4330_CR3","doi-asserted-by":"publisher","first-page":"7126","DOI":"10.1021\/acs.est.6b00403","volume":"50","author":"R Beauvais-Fluck","year":"2016","unstructured":"Beauvais-Fluck R, Slaveykova VI, Cosio C (2016) Transcriptomic and physiological responses of the green microalga Chlamydomonas reinhardtii during short-term exposure to subnanomolar Methylmercury concentrations. Environ Sci Technol 50(13):7126\u20137134. https:\/\/doi.org\/10.1021\/acs.est.6b00403","journal-title":"Environ Sci Technol"},{"key":"4330_CR4","doi-asserted-by":"publisher","first-page":"137647","DOI":"10.1016\/j.scitotenv.2020.137647","volume":"721","author":"K Bishop","year":"2020","unstructured":"Bishop K, Shanley JB, Riscassi A, de Wit HA, Ekl\u00f6f K, Meng B, Mitchell C, Osterwalder S, Schuster PF, Webster J, Zhu W (2020) Recent advances in Understanding and measurement of mercury in the environment: terrestrial hg cycling. Sci Total Environ 721:137647. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.137647","journal-title":"Sci Total Environ"},{"issue":"3","key":"4330_CR5","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1111\/1462-2920.13398","volume":"19","author":"A Bussard","year":"2017","unstructured":"Bussard A, Corre E, Hubas C, Duvernois-Berthet E, Le Corguille G, Jourdren L, Coulpier F, Claquin P, Lopez PJ (2017) Physiological adjustments and transcriptome reprogramming are involved in the acclimation to salinity gradients in diatoms. Environ Microbiol 19(3):909\u2013925. https:\/\/doi.org\/10.1111\/1462-2920.13398","journal-title":"Environ Microbiol"},{"issue":"6","key":"4330_CR6","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1111\/tpj.14508","volume":"100","author":"M Cecchin","year":"2019","unstructured":"Cecchin M, Marcolungo L, Rossato M, Girolomoni L, Cosentino E, Cuine S, Li-Beisson Y, Delledonne M, Ballottari M (2019) Chlorella vulgaris genome assembly and annotation reveals the molecular basis for metabolic acclimation to high light conditions. Plant J 100(6):1289\u20131305. https:\/\/doi.org\/10.1111\/tpj.14508","journal-title":"Plant J"},{"issue":"2","key":"4330_CR7","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1111\/nph.13787","volume":"210","author":"MH Cruz de Carvalho","year":"2016","unstructured":"Cruz de Carvalho MH, Sun HX, Bowler C, ChuaNH (2016) Noncoding and coding transcriptome responses of a marine diatom to phosphate fluctuations. New Phytol 210(2):497\u2013510. https:\/\/doi.org\/10.1111\/nph.13787","journal-title":"New Phytol"},{"issue":"5","key":"4330_CR8","doi-asserted-by":"publisher","first-page":"104460","DOI":"10.1016\/j.jece.2020.104460","volume":"8","author":"M Danouche","year":"2020","unstructured":"Danouche M, El Ghachtouli N, El Baouchi A, El Arroussi H (2020) Heavy metals phycoremediation using tolerant green microalgae: enzymatic and non-enzymatic antioxidant systems for the management of oxidative stress. J Environ Chem Eng 8(5):104460. https:\/\/doi.org\/10.1016\/j.jece.2020.104460","journal-title":"J Environ Chem Eng"},{"key":"4330_CR9","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.jhazmat.2016.10.052","volume":"324","author":"C Du","year":"2017","unstructured":"Du C, Zhang B, He Y, Hu C, Ng QX, Zhang H, Ong CN (2017) Biological effect of aqueous C60 aggregates on Scenedesmus obliquus revealed by transcriptomics and non-targeted metabolomics. J Hazard Mater 324:221\u2013229. https:\/\/doi.org\/10.1016\/j.jhazmat.2016.10.052","journal-title":"J Hazard Mater"},{"issue":"2","key":"4330_CR10","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.plantsci.2008.10.008","volume":"176","author":"I Duquesnoy","year":"2009","unstructured":"Duquesnoy I, Goupil P, Nadaud I, Branlard G, Piquet-Pissaloux A, Ledoigt G (2009) Identification of Agrostis tenuis leaf proteins in response to As(V) and As(III) induced stress using a proteomics approach. Plant Sci 176(2):206\u2013213. https:\/\/doi.org\/10.1016\/j.plantsci.2008.10.008","journal-title":"Plant Sci"},{"key":"4330_CR11","doi-asserted-by":"publisher","first-page":"149464","DOI":"10.1016\/j.scitotenv.2021.149464","volume":"799","author":"J Elleuch","year":"2021","unstructured":"Elleuch J, Hmani R, Drira M, Michaud P, Fendri I, Abdelkafi S (2021) Potential of three local marine microalgae from Tunisian Coasts for cadmium, lead and chromium removals. Sci Total Environ 799:149464. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.149464","journal-title":"Sci Total Environ"},{"key":"4330_CR12","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.jes.2022.07.013","volume":"119","author":"Z Gao","year":"2022","unstructured":"Gao Z, Zheng W, Li Y, Liu Y, Wu M, Li S, Li P, Liu G, Fu X, Wang S, Wang F, Cai Y, Feng X, Gu B, Zhong H, Yin Y (2022) Mercury transformation processes in nature: critical knowledge gaps and perspectives for moving forward. J Environ Sci 119:152\u2013165. https:\/\/doi.org\/10.1016\/j.jes.2022.07.013","journal-title":"J Environ Sci"},{"key":"4330_CR14","doi-asserted-by":"publisher","unstructured":"Geng W, Xiao X, Zhang L, Ni W, Li N, Li Y (2021) Response and tolerance ability of Chlorella vulgaris to cadmium pollution stress. Environ Technol 1\u201311. https:\/\/doi.org\/10.1080\/09593330.2021.1950841","DOI":"10.1080\/09593330.2021.1950841"},{"issue":"12","key":"4330_CR15","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.plaphy.2010.08.016","volume":"48","author":"SS Gill","year":"2010","unstructured":"Gill SS, Tuteja N (2010) Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. Plant Physiol Biochem 48(12):909\u2013930. https:\/\/doi.org\/10.1016\/j.plaphy.2010.08.016","journal-title":"Plant Physiol Biochem"},{"key":"4330_CR16","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.cbi.2015.06.013","volume":"238","author":"V Gomez-Jacinto","year":"2015","unstructured":"Gomez-Jacinto V, Garcia-Barrera T, Gomez-Ariza JL, Garbayo-Nores I, Vilchez-Lobato C (2015) Elucidation of the defence mechanism in microalgae Chlorella Sorokiniana under mercury exposure identification of Hg-phytochelatins. Chem Biol Interact 238:82\u201390. https:\/\/doi.org\/10.1016\/j.cbi.2015.06.013","journal-title":"Chem Biol Interact"},{"key":"4330_CR13","doi-asserted-by":"publisher","unstructured":"Guo L, Li S, Cheng D, Lu X, Gao X, Zhang L, Lu J (2024) Integrated proteome and pangenome analysis revealed the variation of microalga isochrysis Galbana and associated bacterial community to 2,6-Di-tert-butyl-p-cresol (BHT) stress. World J Microb Biot 40(11). https:\/\/doi.org\/10.1007\/s11274-024-04171-z","DOI":"10.1007\/s11274-024-04171-z"},{"issue":"2","key":"4330_CR17","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.aquatox.2005.02.008","volume":"74","author":"CS Hassler","year":"2005","unstructured":"Hassler CS, Behra R, Wilkinson KJ (2005) Impact of zinc acclimation on bioaccumulation and homeostasis in Chlorella kesslerii. Aquat Toxicol 74(2):139\u2013149. https:\/\/doi.org\/10.1016\/j.aquatox.2005.02.008","journal-title":"Aquat Toxicol"},{"key":"4330_CR32","doi-asserted-by":"publisher","unstructured":"Insights from the morphotype-dependent metal tolerance in Phaeodactylum tricornutum Ecotoxicol Environ Saf 208:111715. https:\/\/doi.org\/10.1016\/j.ecoenv.2020.111715","DOI":"10.1016\/j.ecoenv.2020.111715"},{"key":"4330_CR18","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/978-3-319-54910-1_4","volume":"979","author":"T Ishikawa","year":"2017","unstructured":"Ishikawa T, Tamaki S, Maruta T, Shigeoka S (2017) Biochemistry and physiology of reactive oxygen species in Euglena. Adv Exp Med Biol 979:47\u201364. https:\/\/doi.org\/10.1007\/978-3-319-54910-1_4","journal-title":"Adv Exp Med Biol"},{"key":"4330_CR19","doi-asserted-by":"publisher","first-page":"122860","DOI":"10.1016\/j.biortech.2020.122860","volume":"302","author":"M Jin","year":"2020","unstructured":"Jin M, Xiao X, Qin L, Geng W, Gao Y, Li L, Xue J (2020) Physiological and morphological responses and tolerance mechanisms of Isochrysis Galbana to Cr(VI) stress. Bioresour Technol 302:122860. https:\/\/doi.org\/10.1016\/j.biortech.2020.122860","journal-title":"Bioresour Technol"},{"key":"4330_CR20","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1093\/nar\/gkm882","volume":"36","author":"M Kanehisa","year":"2008","unstructured":"Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y (2008) KEGG for linking genomes to life and the environment. Nucleic Acids Res 36:480\u2013484. https:\/\/doi.org\/10.1093\/nar\/gkm882","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"4330_CR21","doi-asserted-by":"publisher","first-page":"2420","DOI":"10.1038\/s41467-019-10376-w","volume":"10","author":"MS Kang","year":"2019","unstructured":"Kang MS, Ryu E, Lee SW, Park J, Ha NY, Ra JS, Kim YJ, Kim J, Abdel-Rahman M, Park SH, Lee KY, Kim H, Kang S, Myung K (2019) Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes. Nat Commun 10(1):2420. https:\/\/doi.org\/10.1038\/s41467-019-10376-w","journal-title":"Nat Commun"},{"key":"4330_CR22","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.algal.2016.05.026","volume":"18","author":"D Kumar","year":"2016","unstructured":"Kumar D, Pandey LK, Gaur JP (2016) Metal sorption by algal biomass: from batch to continuous system. Algal Res 18:95\u2013109. https:\/\/doi.org\/10.1016\/j.algal.2016.05.026","journal-title":"Algal Res"},{"key":"4330_CR23","doi-asserted-by":"publisher","first-page":"122886","DOI":"10.1016\/j.biortech.2020.122886","volume":"303","author":"YK Leong","year":"2020","unstructured":"Leong YK, Chang JS (2020) Bioremediation of heavy metals using microalgae: recent advances and mechanisms. Bioresour Technol 303:122886. https:\/\/doi.org\/10.1016\/j.biortech.2020.122886","journal-title":"Bioresour Technol"},{"key":"4330_CR24","doi-asserted-by":"publisher","first-page":"129771","DOI":"10.1016\/j.chemosphere.2021.129771","volume":"274","author":"C Li","year":"2021","unstructured":"Li C, Zheng C, Fu H, Zhai S, Hu F, Naveed S, Zhang C, Ge Y (2021) Contrasting detoxification mechanisms of Chlamydomonas reinhardtii under cd and Pb stress. Chemosphere 274:129771. https:\/\/doi.org\/10.1016\/j.chemosphere.2021.129771","journal-title":"Chemosphere"},{"key":"4330_CR26","doi-asserted-by":"publisher","first-page":"118266","DOI":"10.1016\/j.watres.2022.118266","volume":"215","author":"Y Li","year":"2022","unstructured":"Li Y, Li D, Song B, Li Y (2022) The potential of mercury methylation and demethylation by 15 species of marine microalgae. Water Res 215:118266. https:\/\/doi.org\/10.1016\/j.watres.2022.118266","journal-title":"Water Res"},{"key":"4330_CR25","doi-asserted-by":"publisher","first-page":"168690","DOI":"10.1016\/j.scitotenv.2023.168690","volume":"911","author":"S Li","year":"2024","unstructured":"Li S, Li Z, Wu M, Zhou Y, Tang W, Zhong H (2024) Mercury transformations in algae, plants, and animals: the occurrence, mechanisms, and gaps. Sci Total Environ 911:168690. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.168690","journal-title":"Sci Total Environ"},{"issue":"8","key":"4330_CR27","doi-asserted-by":"publisher","first-page":"4961","DOI":"10.1021\/acs.est.1c06558","volume":"56","author":"X Liang","year":"2022","unstructured":"Liang X, Zhu N, Johs A, Chen H, Pelletier DA, Zhang L, Yin X, Gao Y, Zhao J, Gu B (2022) Mercury reduction, uptake, and species transformation by freshwater Alga chlorella vulgaris under sunlit and dark conditions. Environ Sci Technol 56(8):4961\u20134969. https:\/\/doi.org\/10.1021\/acs.est.1c06558","journal-title":"Environ Sci Technol"},{"key":"4330_CR29","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.hal.2017.10.007","volume":"70","author":"S Liu","year":"2017","unstructured":"Liu S, Yu Z, Song X, Cao X (2017) Effects of modified clay on the physiological and photosynthetic activities of Amphidinium Carterae Hulburt. Harmful Algae 70:64\u201372. https:\/\/doi.org\/10.1016\/j.hal.2017.10.007","journal-title":"Harmful Algae"},{"key":"4330_CR28","doi-asserted-by":"publisher","first-page":"142065","DOI":"10.1016\/j.cej.2023.142065","volume":"461","author":"D Liu","year":"2023","unstructured":"Liu D, Yang W, Lv Y, Li S, Qv M, Dai D, Zhu L (2023) Pollutant removal and toxic response mechanisms of freshwater microalgae chlorella Sorokiniana under exposure of tetrabromobisphenol A and cadmium. Chem Eng J 461:142065. https:\/\/doi.org\/10.1016\/j.cej.2023.142065","journal-title":"Chem Eng J"},{"key":"4330_CR30","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.jes.2020.06.033","volume":"99","author":"T Lu","year":"2021","unstructured":"Lu T, Zhang Q, Zhang Z, Hu B, Chen J, Chen J, Qian H (2021) Pollutant toxicology with respect to microalgae and cyanobacteria. J Environ Sci (China) 99:175\u2013186. https:\/\/doi.org\/10.1016\/j.jes.2020.06.033","journal-title":"J Environ Sci (China)"},{"key":"4330_CR31","unstructured":"Ma J, Zhou B, Chen F, Pan K (2021) How marine diatoms cope with metal challenge"},{"issue":"4","key":"4330_CR33","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/s002440010122","volume":"39","author":"SM Macfie","year":"2000","unstructured":"Macfie SM, Welbourn PM (2000) The cell wall as a barrier to uptake of metal ions in the unicellular green Alga Chlamydomonas reinhardtii (Chlorophyceae). Arch Environ Contam Toxicol 39(4):413\u2013419. https:\/\/doi.org\/10.1007\/s002440010122","journal-title":"Arch Environ Contam Toxicol"},{"issue":"4\u20135","key":"4330_CR34","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1080\/15216540500092419","volume":"57","author":"H Masai","year":"2005","unstructured":"Masai H, You Z, Arai K (2005) Control of DNA replication: regulation and activation of eukaryotic replicative helicase. MCM. IUBMB Life 57(4\u20135):323\u2013335. https:\/\/doi.org\/10.1080\/15216540500092419","journal-title":"IUBMB Life"},{"issue":"8","key":"4330_CR35","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1016\/s1001-0742(11)60931-5","volume":"24","author":"WO Maznah","year":"2012","unstructured":"Maznah WO, Al-Fawwaz AT, Surif M (2012) Biosorption of copper and zinc by immobilised and free algal biomass, and the effects of metal biosorption on the growth and cellular structure of Chlorella Spand Chlamydomonas Sp isolated from rivers in Penang. Malaysia J Environ Sci (China) 24(8):1386\u20131393. https:\/\/doi.org\/10.1016\/s1001-0742(11)60931-5","journal-title":"Malaysia J Environ Sci (China)"},{"issue":"6","key":"4330_CR36","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.jplph.2012.01.004","volume":"169","author":"N Nounjan","year":"2012","unstructured":"Nounjan N, Nghia PT, Theerakulpisut P (2012) Exogenous proline and Trehalose promote recovery of rice seedlings from salt-stress and differentially modulate antioxidant enzymes and expression of related genes. J Plant Physiol 169(6):596\u2013604. https:\/\/doi.org\/10.1016\/j.jplph.2012.01.004","journal-title":"J Plant Physiol"},{"issue":"12","key":"4330_CR37","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1016\/j.marpolbul.2005.06.023","volume":"50","author":"DM Pampanin","year":"2005","unstructured":"Pampanin DM, Camus L, Gomiero A, Marangon I, Volpato E, Nasci C (2005) Susceptibility to oxidative stress of mussels (Mytilus galloprovincialis) in the Venice lagoon (Italy). Mar Pollut Bull 50(12):1548\u20131557. https:\/\/doi.org\/10.1016\/j.marpolbul.2005.06.023","journal-title":"Mar Pollut Bull"},{"issue":"13","key":"4330_CR38","doi-asserted-by":"publisher","first-page":"5951","DOI":"10.5194\/acp-10-5951-2010","volume":"10","author":"N Pirrone","year":"2010","unstructured":"Pirrone N, Cinnirella S, Feng X, Finkelman RB, Friedli HR, Leaner J, Mason R, Mukherjee AB, Stracher GB, Streets DG, Telmer K (2010) Global mercury emissions to the atmosphere from anthropogenic and natural sources. Atmos Chem Phys 10(13):5951\u20135964. https:\/\/doi.org\/10.5194\/acp-10-5951-2010","journal-title":"Atmos Chem Phys"},{"issue":"1","key":"4330_CR39","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s10811-017-1124-4","volume":"30","author":"S Poong","year":"2017","unstructured":"Poong S, Lim P, Phang S, Wong C, Pai T, Chen C, Yang C, Liu C (2017) Transcriptome sequencing of an Antarctic microalga, Chlorella sp(Trebouxiophyceae, Chlorophyta) subjected to short-term ultraviolet radiation stress. J Appl Phycol 30(1):87\u201399. https:\/\/doi.org\/10.1007\/s10811-017-1124-4","journal-title":"J Appl Phycol"},{"key":"4330_CR40","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.biortech.2018.09.065","volume":"270","author":"R Singh","year":"2018","unstructured":"Singh R, Upadhyay AK, Chandra P, Singh DP (2018) Sodium chloride incites reactive oxygen species in green algae Chlorococcum humicola and Chlorella vulgaris: implication on lipid synthesis, mineral nutrients and antioxidant system. Bioresour Technol 270:489\u2013497. https:\/\/doi.org\/10.1016\/j.biortech.2018.09.065","journal-title":"Bioresour Technol"},{"key":"4330_CR41","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.ecoenv.2014.12.019","volume":"113","author":"K Suresh Kumar","year":"2015","unstructured":"Suresh Kumar K, Dahms HU, Won EJ, Lee JS, Shin KH (2015) Microalgae - A promising tool for heavy metal remediation. Ecotoxicol Environ Saf 113:329\u2013352. https:\/\/doi.org\/10.1016\/j.ecoenv.2014.12.019","journal-title":"Ecotoxicol Environ Saf"},{"key":"4330_CR42","doi-asserted-by":"publisher","first-page":"117443","DOI":"10.1016\/j.envpol.2021.117443","volume":"285","author":"S Tripathi","year":"2021","unstructured":"Tripathi S, Poluri KM (2021) Heavy metal detoxification mechanisms by microalgae: insights from transcriptomics analysis. Environ Pollut 285:117443. https:\/\/doi.org\/10.1016\/j.envpol.2021.117443","journal-title":"Environ Pollut"},{"issue":"2","key":"4330_CR43","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.scitotenv.2010.10.011","volume":"409","author":"M Vogel","year":"2010","unstructured":"Vogel M, Gunther A, Rossberg A, Li B, Bernhard G, Raff J (2010) Biosorption of U(VI) by the green algae Chlorella vulgaris in dependence of pH value and cell activity. Sci Total Environ 409(2):384\u2013395. https:\/\/doi.org\/10.1016\/j.scitotenv.2010.10.011","journal-title":"Sci Total Environ"},{"issue":"15","key":"4330_CR44","doi-asserted-by":"publisher","first-page":"3543","DOI":"10.1242\/jcs.02477","volume":"118","author":"M Weinberger","year":"2005","unstructured":"Weinberger M, Ramachandran L, Feng L, Sharma K, Sun X, Marchetti M, Huberman JA, Burhans WC (2005) Apoptosis in budding yeast caused by defects in initiation of DNA replication. J Cell Sci 118(15):3543\u20133553. https:\/\/doi.org\/10.1242\/jcs.02477","journal-title":"J Cell Sci"},{"issue":"22","key":"4330_CR45","doi-asserted-by":"publisher","first-page":"5029","DOI":"10.5194\/bg-14-5029-2017","volume":"14","author":"Y Wu","year":"2017","unstructured":"Wu Y, Yue F, Xu J, Beardall J (2017) Differential photosynthetic responses of marine planktonic and benthic diatoms to ultraviolet radiation under various temperature regimes. Biogeosciences 14(22):5029\u20135037. https:\/\/doi.org\/10.5194\/bg-14-5029-2017","journal-title":"Biogeosciences"},{"key":"4330_CR46","doi-asserted-by":"publisher","first-page":"105805","DOI":"10.1016\/j.marenvres.2022.105805","volume":"183","author":"X Xiao","year":"2022","unstructured":"Xiao X, Li W, Jin M, Zhang L, Qin L, Geng W (2022) Responses and tolerance mechanisms of microalgae to heavy metal stress: A review. Mar Environ Res 183:105805. https:\/\/doi.org\/10.1016\/j.marenvres.2022.105805","journal-title":"Mar Environ Res"},{"issue":"5","key":"4330_CR47","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.3390\/microorganisms11051108","volume":"11","author":"X Xiao","year":"2023","unstructured":"Xiao X, Li W, Li S, Zuo X, Liu J, Guo L, Lu X, Zhang L (2023) The growth Inhibition of polyethylene nanoplastics on the bait-microalgae Isochrysis Galbana based on the transcriptome analysis. Microorganisms 11(5):1108. https:\/\/doi.org\/10.3390\/microorganisms11051108","journal-title":"Microorganisms"},{"key":"4330_CR48","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.biortech.2016.01.038","volume":"205","author":"JQ Xiong","year":"2016","unstructured":"Xiong JQ, Kurade MB, Abou-Shanab RA, Ji MK, Choi J, Kim JO, Jeon BH (2016) Biodegradation of carbamazepine using freshwater microalgae Chlamydomonas Mexicana and Scenedesmus obliquus and the determination of its metabolic fate. Bioresour Technol 205:183\u2013190. https:\/\/doi.org\/10.1016\/j.biortech.2016.01.038","journal-title":"Bioresour Technol"},{"issue":"8","key":"4330_CR49","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1016\/j.str.2011.07.001","volume":"19","author":"S Yuan","year":"2011","unstructured":"Yuan S, Yu X, Asara JM, Heuser JE, Ludtke SJ, Akey CW (2011) The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3. Structure 19(8):1084\u20131096. https:\/\/doi.org\/10.1016\/j.str.2011.07.001","journal-title":"Structure"},{"issue":"2","key":"4330_CR52","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.etap.2011.12.024","volume":"33","author":"W Zhang","year":"2012","unstructured":"Zhang W, Zhang M, Lin K, Sun W, Xiong B, Guo M, Cui X, Fu R (2012) Eco-toxicological effect of carbamazepine on Scenedesmus obliquus and Chlorella pyrenoidosa. Environ Toxicol Pharmacol 33(2):344\u2013352. https:\/\/doi.org\/10.1016\/j.etap.2011.12.024","journal-title":"Environ Toxicol Pharmacol"},{"issue":"9","key":"4330_CR51","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1016\/j.chemosphere.2013.01.002","volume":"92","author":"J Zhang","year":"2013","unstructured":"Zhang J, Ding T, Zhang C (2013) Biosorption and toxicity responses to arsenite (As[III]) in Scenedesmus quadricauda. Chemosphere 92(9):1077\u20131084. https:\/\/doi.org\/10.1016\/j.chemosphere.2013.01.002","journal-title":"Chemosphere"},{"issue":"1","key":"4330_CR50","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.eehl.2022.04.002","volume":"1","author":"H Zhang","year":"2022","unstructured":"Zhang H, Wang W, Lin C, Feng X, Shi J, Jiang G, Larssen T (2022) Decreasing mercury levels in consumer fish over the three decades of increasing mercury emissions in China. EEH 1(1):46\u201352. https:\/\/doi.org\/10.1016\/j.eehl.2022.04.002","journal-title":"EEH"}],"container-title":["World Journal of Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-025-04330-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11274-025-04330-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-025-04330-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T04:46:41Z","timestamp":1749444401000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11274-025-04330-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["4330"],"URL":"https:\/\/doi.org\/10.1007\/s11274-025-04330-w","relation":{},"ISSN":["0959-3993","1573-0972"],"issn-type":[{"value":"0959-3993","type":"print"},{"value":"1573-0972","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"23 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"164"}}