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While\n                    <jats:italic>Saccharomyces<\/jats:italic>\n                    species remain the predominant industrial yeasts, their limited ability to assimilate lactose, pentoses, and glycerol, as well as their sensitivity to lignocellulose-derived inhibitors, restricts their efficient application in bioprocesses based on using industrial byproducts as fermentation media. In contrast, several non-\n                    <jats:italic>albicans Candida<\/jats:italic>\n                    species exhibit broad substrate utilization capacities and enhanced tolerance to industrial stresses, making them attractive candidates for the bioconversion of agroindustrial residues. This review critically examines recent advances in the genomic, metabolic, and physiological characterization of promising non-albicans\n                    <jats:italic>Candida<\/jats:italic>\n                    species, including\n                    <jats:italic>Candida tropicalis<\/jats:italic>\n                    ,\n                    <jats:italic>Candida parapsilosis<\/jats:italic>\n                    ,\n                    <jats:italic>Candida viswanathii<\/jats:italic>\n                    ,\n                    <jats:italic>Candida sojae<\/jats:italic>\n                    , and\n                    <jats:italic>Candida maltosa<\/jats:italic>\n                    . Emphasis is given to genome-scale metabolic models, carbon assimilation pathways, stress-response mechanisms, and metabolic engineering approaches aiming at the production of value-added compounds. By identifying current achievements, knowledge gaps, and biotechnological bottlenecks, this review highlights the potential of these yeasts as emerging platforms for sustainable bioprocesses within a circular bioeconomy framework.\n                  <\/jats:p>","DOI":"10.1007\/s11274-026-05245-w","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:01:00Z","timestamp":1789110060000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genomic features, metabolism, and biotechnological applications of Candida tropicalis and other non-albicans Candida species"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2468-2750","authenticated-orcid":false,"given":"Thaynara Lorenzoni","family":"Entringer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7869-8144","authenticated-orcid":false,"given":"Wendel Batista","family":"da Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"5245_CR1","doi-asserted-by":"publisher","unstructured":"Abi-chacra \u00c9A, Souza LOP, Cruz LP, Braga-Silva LA, Gon\u00e7alves DS, Sodr\u00e9 CL, Ribeiro MD, Seabra SH, Figueiredo-Carvalho MHG, Barbedo LS, Zancop\u00e9-Oliveira RM, Ziccardi M, Santos ALS (2013) Phenotypical properties associated with virulence from clinical isolates belonging to the Candida parapsilosis complex. 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