{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:32:32Z","timestamp":1793287952517,"version":"4.5.0"},"reference-count":78,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Bengbu University High level Talent Research Initiation Fund Project","award":["No. 2025GQD033, 2025GQD032, 2025GQD034"],"award-info":[{"award-number":["No. 2025GQD033, 2025GQD032, 2025GQD034"]}],"id":[{"id":"https:\/\/ror.org\/05p8d2v16","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Bengbu University Interdisciplinary Research and Innovation Team","award":["No. 2025XKJCTD03"],"award-info":[{"award-number":["No. 2025XKJCTD03"]}],"id":[{"id":"https:\/\/ror.org\/05p8d2v16","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Peak Discipline of Bengbu University","award":["No. 2025GFXK02"],"award-info":[{"award-number":["No. 2025GFXK02"]}],"id":[{"id":"https:\/\/ror.org\/05p8d2v16","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Anhui Provincial Department of Education University Scientific Research Project","award":["NO. 2025AHGXZK30648, 2025AHGXZK31112"],"award-info":[{"award-number":["NO. 2025AHGXZK30648, 2025AHGXZK31112"]}],"id":[{"id":"https:\/\/ror.org\/012m7k033","id-type":"ROR","asserted-by":"crossref"}]},{"name":"the National Natural Science Foundation of China","award":["32171623"],"award-info":[{"award-number":["32171623"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Microbiol Biotechnol"],"DOI":"10.1007\/s11274-026-05294-1","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:26:25Z","timestamp":1790573185000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quorum sensing molecules enhance cadmium detoxification and cellular removal in the marine diatom Phaeodactylum tricornutum"],"prefix":"10.1007","volume":"42","author":[{"given":"Qingnan","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxuan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiale","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglei","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanping","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"5294_CR1","doi-asserted-by":"publisher","first-page":"3609","DOI":"10.1007\/s13197-016-2346-1","volume":"53","author":"JA Bai","year":"2016","unstructured":"Bai JA, Rai R, V (2016) Effect of small chain N acyl homoserine lactone quorum sensing signals on biofilms of food-borne pathogens. J Food Sci Technol 53:3609\u20133614. https:\/\/doi.org\/10.1007\/s13197-016-2346-1","journal-title":"J Food Sci Technol"},{"key":"5294_CR2","doi-asserted-by":"publisher","first-page":"117357","DOI":"10.1016\/j.fuel.2020.117357","volume":"268","author":"M Branco-Vieira","year":"2020","unstructured":"Branco-Vieira M, San Martin S, Agurto C, Freitas MV, Martins AA, Mata TM, Caetano NS (2020) Biotechnological potential of Phaeodactylum tricornutum for biorefinery processes. Fuel 268:117357. https:\/\/doi.org\/10.1016\/j.fuel.2020.117357","journal-title":"Fuel"},{"key":"5294_CR3","doi-asserted-by":"publisher","first-page":"7640","DOI":"10.1021\/es2002259","volume":"45","author":"T Brembu","year":"2011","unstructured":"Brembu T, J\u00f8rstad M, Winge P, Valle KC, Bones AM (2011) Genome-wide profiling of responses to cadmium in the diatom Phaeodactylum tricornutum. Environ Sci Technol 45:7640\u20137647. https:\/\/doi.org\/10.1021\/es2002259","journal-title":"Environ Sci Technol"},{"key":"5294_CR4","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1016\/j.ecolind.2017.07.057","volume":"95","author":"MT Cabrita","year":"2018","unstructured":"Cabrita MT, Duarte B, Gameiro C, Godinho RM, Ca\u00e7ador I (2018) Photochemical features and trace element substituted chlorophylls as early detection biomarkers of metal exposure in the model diatom Phaeodactylum tricornutum. Ecol Ind 95:1038\u20131052. https:\/\/doi.org\/10.1016\/j.ecolind.2017.07.057","journal-title":"Ecol Ind"},{"key":"5294_CR5","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1186\/s12870-022-03865-6","volume":"22","author":"X Cao","year":"2022","unstructured":"Cao X, Zhao Q, Sun Y, Yu M, Liu F, Zhang Z, Jia Z, Song S (2022) Cellular messengers involved in the inhibition of the Arabidopsis primary root growth by bacterial quorum-sensing signal N-decanoyl-L-homoserine lactone. BMC Plant Biol 22:488. https:\/\/doi.org\/10.1186\/s12870-022-03865-6","journal-title":"BMC Plant Biol"},{"key":"5294_CR6","doi-asserted-by":"publisher","first-page":"8142","DOI":"10.1021\/es0506962","volume":"39","author":"RM Cory","year":"2005","unstructured":"Cory RM, Mcknight DM (2005) Fluorescence spectroscopy reveals ubiquitous presence of oxidized and reduced quinones in dissolved organic matter. Environ Sci Technol 39:8142\u20138149. https:\/\/doi.org\/10.1021\/es0506962","journal-title":"Environ Sci Technol"},{"key":"5294_CR7","doi-asserted-by":"publisher","first-page":"113567","DOI":"10.1016\/j.ecoenv.2022.113567","volume":"238","author":"B Dai","year":"2022","unstructured":"Dai B, Peng Y, Zhang M, Yang M, Wu Y, Guo X (2022) Insight into the effects of biological treatment on the binding properties of copper onto dissolved organic matter derived from coking wastewater. Ecotoxicol Environ Saf 238:113567. https:\/\/doi.org\/10.1016\/j.ecoenv.2022.113567","journal-title":"Ecotoxicol Environ Saf"},{"key":"5294_CR8","doi-asserted-by":"publisher","first-page":"122963","DOI":"10.1016\/j.biortech.2020.122963","volume":"303","author":"J Deng","year":"2020","unstructured":"Deng J, Fu D, Hu W, Lu X, Wu Y, Bryan H (2020) Physiological responses and accumulation ability of Microcystis aeruginosa to zinc and cadmium: Implications for bioremediation of heavy metal pollution. Bioresour Technol 303:122963. https:\/\/doi.org\/10.1016\/j.biortech.2020.122963","journal-title":"Bioresour Technol"},{"key":"5294_CR9","doi-asserted-by":"publisher","first-page":"629","DOI":"10.7541\/2017.80","volume":"41","author":"Y Dou","year":"2017","unstructured":"Dou Y, Jiang Z, Zhang W, Gao J, Jiang M, Shi X, Zhou W (2017) Effects of AHLs on PSII photochemistry activity and photosynthesis crucial enzymes of Chlorella vulgaris. Acta Hydrobiol Sin 41:629\u2013636. https:\/\/doi.org\/10.7541\/2017.80","journal-title":"Acta Hydrobiol Sin"},{"key":"5294_CR10","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.3390\/microorganisms9071391","volume":"9","author":"L Dow","year":"2021","unstructured":"Dow L (2021) How do quorum-sensing signals mediate algae\u2013bacteria interactions? Microorganisms 9:1391. https:\/\/doi.org\/10.3390\/microorganisms9071391","journal-title":"Microorganisms"},{"key":"5294_CR11","doi-asserted-by":"publisher","first-page":"134061","DOI":"10.1016\/j.scitotenv.2019.134061","volume":"696","author":"X Fan","year":"2019","unstructured":"Fan X, Peng P, Huang H, Peng C, Gao Y, Ren H (2019) Undesirable effects of exogenous N-acyl homoserine lactones on moving bed biofilm reactor treating medium-strength synthetic wastewater. Sci Total Environ 696:134061. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.134061","journal-title":"Sci Total Environ"},{"key":"5294_CR12","doi-asserted-by":"publisher","first-page":"128929","DOI":"10.1016\/j.biortech.2023.128929","volume":"376","author":"MB Fard","year":"2023","unstructured":"Fard MB, Wu D (2023) Potential interactive effect on biomass and bio-polymeric substances of microalgal-bacterial aerobic granular sludge as a valuable resource for sustainable development. Bioresour Technol 376:128929. https:\/\/doi.org\/10.1016\/j.biortech.2023.128929","journal-title":"Bioresour Technol"},{"key":"5294_CR14","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s11771-020-4277-2","volume":"27","author":"Q Gao","year":"2020","unstructured":"Gao Q, Tang D, Song P, Zhou J, Li H (2020) Characterization of acylated homoserine lactone derivatives and their influence on biofilms of Acidithiobacillus ferrooxidans BY-3 under arsenic stress. J Cent South Univ 27:52\u201363. https:\/\/doi.org\/10.1007\/s11771-020-4277-2","journal-title":"J Cent South Univ"},{"key":"5294_CR13","doi-asserted-by":"publisher","first-page":"128567","DOI":"10.1016\/j.biortech.2022.128567","volume":"370","author":"H Gao","year":"2022","unstructured":"Gao H, Zhao R, Wu Z, Ye J, Duan L, Yu R (2022) New insights into exogenous N-acyl-homoserine lactone manipulation in biological nitrogen removal system against ZnO nanoparticle shock. Bioresour Technol 370:128567. https:\/\/doi.org\/10.1016\/j.biortech.2022.128567","journal-title":"Bioresour Technol"},{"key":"5294_CR15","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1177\/1082013217717611","volume":"23","author":"LJ German-B\u00e1ez","year":"2017","unstructured":"German-B\u00e1ez LJ, Valdez-Flores MA, F\u00e9lix-Medina JV, Norzagaray-Valenzuela CD, Santos-Ballardo DU, Reyes-Moreno C, Shelton LM, Valdez-Ortiz A (2017) Chemical composition and physicochemical properties of Phaeodactylum tricornutum microalgal residual biomass. Food Sci Technol Int 23:681\u2013689. https:\/\/doi.org\/10.1177\/1082013217717611","journal-title":"Food Sci Technol Int"},{"key":"5294_CR16","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1080\/1040841x.2019.1624499","volume":"45","author":"L Girard","year":"2019","unstructured":"Girard L (2019) Quorum sensing in Vibrio spp.: the complexity of multiple signalling molecules in marine and aquatic environments. Crit Rev Microbiol 45:451\u2013471. https:\/\/doi.org\/10.1080\/1040841x.2019.1624499","journal-title":"Crit Rev Microbiol"},{"key":"5294_CR17","doi-asserted-by":"publisher","first-page":"3867","DOI":"10.1111\/1462-2920.13346","volume":"18","author":"X Guo","year":"2016","unstructured":"Guo X, Liu X, Wu L, Pan J, Yang H (2016) The algicidal activity of Aeromonas sp. strain GLY-2107 against bloom\u2010forming Microcystis aeruginosa is regulated by N\u2010acyl homoserine lactone\u2010mediated quorum sensing. Environ Microbiol 18:3867\u20133883. https:\/\/doi.org\/10.1111\/1462-2920.13346","journal-title":"Environ Microbiol"},{"key":"5294_CR18","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.3390\/pathogens10121561","volume":"10","author":"A Hartmann","year":"2021","unstructured":"Hartmann A, Klink S, Rothballer M (2021) Importance of N-acyl-homoserine lactone-based quorum sensing and quorum quenching in pathogen control and plant growth promotion. Pathogens 10:1561. https:\/\/doi.org\/10.3390\/pathogens10121561","journal-title":"Pathogens"},{"key":"5294_CR19","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.jenvman.2018.09.011","volume":"227","author":"A Hedayatkhah","year":"2018","unstructured":"Hedayatkhah A, Cretoiu MS, Emtiazi G, Stal LJ, Bolhuis H (2018) Bioremediation of chromium contaminated water by diatoms with concomitant lipid accumulation for biofuel production. J Environ Manage 227:313\u2013320. https:\/\/doi.org\/10.1016\/j.jenvman.2018.09.011","journal-title":"J Environ Manage"},{"key":"5294_CR20","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1111\/j.1758-2229.2011.00281.x","volume":"3","author":"LR Hmelo","year":"2011","unstructured":"Hmelo LR, Mincer TJ, Van Mooy BS (2011) Possible influence of bacterial quorum sensing on the hydrolysis of sinking particulate organic carbon in marine environments. Environ Microbiol Rep 3:682\u2013688. https:\/\/doi.org\/10.1111\/j.1758-2229.2011.00281.x","journal-title":"Environ Microbiol Rep"},{"key":"5294_CR21","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.biortech.2016.03.068","volume":"211","author":"H Hu","year":"2016","unstructured":"Hu H, He J, Liu J, Yu H, Zhang J (2016) Biofilm activity and sludge characteristics affected by exogenous N-acyl homoserine lactones in biofilm reactors. Bioresour Technol 211:339\u2013347. https:\/\/doi.org\/10.1016\/j.biortech.2016.03.068","journal-title":"Bioresour Technol"},{"key":"5294_CR22","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1038\/nrmicro1836","volume":"6","author":"DT Hughes","year":"2008","unstructured":"Hughes DT, Sperandio V (2008) Inter-kingdom signalling: communication between bacteria and their hosts. Nat Rev Microbiol 6:111\u2013120. https:\/\/doi.org\/10.1038\/nrmicro1836","journal-title":"Nat Rev Microbiol"},{"key":"5294_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/femsec\/fiu030","volume":"91","author":"AN Jatt","year":"2015","unstructured":"Jatt AN, Tang K, Liu J, Zhang Z, Zhang X-H (2015) Quorum sensing in marine snow and its possible influence on production of extracellular hydrolytic enzymes in marine snow bacterium Pantoea ananatis B9. FEMS Microbiol Ecol 91:1\u201313. https:\/\/doi.org\/10.1093\/femsec\/fiu030","journal-title":"FEMS Microbiol Ecol"},{"key":"5294_CR24","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.copbio.2015.02.007","volume":"33","author":"A Kouzuma","year":"2015","unstructured":"Kouzuma A, Watanabe K (2015) Exploring the potential of algae\/bacteria interactions. Curr Opin Biotechnol 33:125\u2013129. https:\/\/doi.org\/10.1016\/j.copbio.2015.02.007","journal-title":"Curr Opin Biotechnol"},{"key":"5294_CR27","doi-asserted-by":"publisher","first-page":"116138","DOI":"10.1016\/j.envpol.2020.116138","volume":"269","author":"Z Li","year":"2020","unstructured":"Li Z, Zhang Y, Huang D, Huang L, Zhang H, Li N, Wang M (2020) Through quorum sensing, Pseudomonas aeruginosa resists noble metal-based nanomaterials toxicity. Environ Pollut 269:116138. https:\/\/doi.org\/10.1016\/j.envpol.2020.116138","journal-title":"Environ Pollut"},{"key":"5294_CR26","doi-asserted-by":"publisher","first-page":"129771","DOI":"10.1016\/j.chemosphere.2021.129771","volume":"274","author":"C Li","year":"2021","unstructured":"Li C, Zheng C, Fu H, Zhai S, Hu F, Naveed S, Zhang C, Ge Y (2021) Contrasting detoxification mechanisms of Chlamydomonas reinhardtii under Cd and Pb stress. Chemosphere 274:129771. https:\/\/doi.org\/10.1016\/j.chemosphere.2021.129771","journal-title":"Chemosphere"},{"key":"5294_CR25","doi-asserted-by":"publisher","first-page":"161995","DOI":"10.1016\/j.scitotenv.2023.161995","volume":"871","author":"C Li","year":"2023","unstructured":"Li C, Li P, Fu H, Chen J, Ye M, Zhai S, Hu F, Zhang.Chunhua, Ge Y, Fortin C (2023) A comparative study of the accumulation and detoxification of copper and zinc in Chlamydomonas reinhardtii: The role of extracellular polymeric substances. Sci Total Environ 871:161995. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.161995","journal-title":"Sci Total Environ"},{"key":"5294_CR29","doi-asserted-by":"publisher","first-page":"127102","DOI":"10.1016\/j.micres.2022.127102","volume":"262","author":"L Liu","year":"2022","unstructured":"Liu L, Zeng X, Zheng J, Zou Y, Qiu S, Dai Y (2022a) AHL-mediated quorum sensing to regulate bacterial substance and energy metabolism: A review. Microbiol Res 262:127102. https:\/\/doi.org\/10.1016\/j.micres.2022.127102","journal-title":"Microbiol Res"},{"key":"5294_CR30","doi-asserted-by":"publisher","first-page":"127161","DOI":"10.1016\/j.biortech.2022.127161","volume":"354","author":"Q Liu","year":"2022","unstructured":"Liu Q, Feng X, Sheng Z, Shi W, Wang S, Li J (2022b) Enhanced wastewater treatment performance by understanding the interaction between algae and bacteria based on quorum sensing. Bioresour Technol 354:127161. https:\/\/doi.org\/10.1016\/j.biortech.2022.127161","journal-title":"Bioresour Technol"},{"key":"5294_CR28","doi-asserted-by":"publisher","first-page":"142065","DOI":"10.1016\/j.cej.2023.142065","volume":"461","author":"D Liu","year":"2023","unstructured":"Liu D, Yang W, Lv Y, Li S, Qv M, Dai D, Zhu L (2023) Pollutant removal and toxic response mechanisms of freshwater microalgae Chlorella sorokiniana under exposure of tetrabromobisphenol A and cadmium. Chem Eng J 461:142065. https:\/\/doi.org\/10.1016\/j.cej.2023.142065","journal-title":"Chem Eng J"},{"key":"5294_CR31","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.envpol.2019.04.018","volume":"250","author":"J Lu","year":"2019","unstructured":"Lu J, Ma Y, Xing G, Li W, Kong X, Li J, Wang L, Yuan H, Yang J (2019) Revelation of microalgae\u2019s lipid production and resistance mechanism to ultra-high Cd stress by integrated transcriptome and physiochemical analyses. Environ Pollut 250:186\u2013195. https:\/\/doi.org\/10.1016\/j.envpol.2019.04.018","journal-title":"Environ Pollut"},{"key":"5294_CR32","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.biortech.2017.09.043","volume":"247","author":"H Ma","year":"2018","unstructured":"Ma H, Wang X, Zhang Y, Hu H, Ren H, Geng J, Ding L (2018) The diversity, distribution and function of N-acyl-homoserine lactone (AHL) in industrial anaerobic granular sludge. Bioresour Technol 247:116\u2013124. https:\/\/doi.org\/10.1016\/j.biortech.2017.09.043","journal-title":"Bioresour Technol"},{"key":"5294_CR33","doi-asserted-by":"publisher","first-page":"102267","DOI":"10.1016\/j.algal.2021.102267","volume":"55","author":"X Ma","year":"2021","unstructured":"Ma X, Chen Y, Liu F, Zhang S, Wei Q (2021) Enhanced tolerance and resistance characteristics of Scenedesmus obliquus FACHB-12 with K3 carrier in cadmium polluted water. Algal Res 55:102267. https:\/\/doi.org\/10.1016\/j.algal.2021.102267","journal-title":"Algal Res"},{"key":"5294_CR34","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.chemosphere.2019.01.064","volume":"221","author":"NR Maddela","year":"2019","unstructured":"Maddela NR, Sheng B, Yuan S, Zhou Z, Villamar-Torres R, Meng F (2019) Roles of quorum sensing in biological wastewater treatment: A critical review. Chemosphere 221:616\u2013629. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.01.064","journal-title":"Chemosphere"},{"key":"5294_CR35","doi-asserted-by":"publisher","first-page":"102762","DOI":"10.1016\/j.algal.2022.102762","volume":"66","author":"Q Mao","year":"2022","unstructured":"Mao Q, Xie Z, Sana I, Zhong Z, Liu T, Pei F, Gao B, Li L (2022) Effect of arsenic accumulation on growth and antioxidant defense system of Chlorella thermophila SM01 and Leptolyngbya sp. XZMQ. Algal Res 66:102762. https:\/\/doi.org\/10.1016\/j.algal.2022.102762","journal-title":"Algal Res"},{"key":"5294_CR36","doi-asserted-by":"publisher","first-page":"834337","DOI":"10.3389\/fmars.2022.834337","volume":"9","author":"U Marion","year":"2022","unstructured":"Marion U, Claire L, St\u00e9phane LH, Rapha\u00ebl L (2022) Quorum sensing regulates bacterial processes that play a major role in marine biogeochemical cycles. Front Mar Sci 9:834337. https:\/\/doi.org\/10.3389\/fmars.2022.834337","journal-title":"Front Mar Sci"},{"key":"5294_CR37","doi-asserted-by":"publisher","first-page":"102463","DOI":"10.1016\/j.algal.2021.102463","volume":"59","author":"OB Meruert","year":"2021","unstructured":"Meruert OB, Assemgul KS, Zhuldyz OM, Miko\u0142aj K, Bolatkhan KZ, Maria Katarzyna W, Huma B, Nurziya RA, Saleh A, Suleyman IA (2021) Potential of microalgae Parachlorella kessleri Bh-2 as bioremediation agent of heavy metals cadmium and chromium. Algal Res 59:102463. https:\/\/doi.org\/10.1016\/j.algal.2021.102463","journal-title":"Algal Res"},{"key":"5294_CR38","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1007\/s12010-017-2591-4","volume":"183","author":"BV Mohite","year":"2017","unstructured":"Mohite BV, Koli SH, Narkhede CP, Patil SN, Patil SV (2017) Prospective of Microbial Exopolysaccharide for Heavy Metal Exclusion. Appl Biochem Biotechnol 183:582\u2013600. https:\/\/doi.org\/10.1007\/s12010-017-2591-4","journal-title":"Appl Biochem Biotechnol"},{"key":"5294_CR39","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1080\/10643389.2019.1583052","volume":"49","author":"S Naveed","year":"2019","unstructured":"Naveed S, Li C, Lu X, Chen S, Yin B, Zhang C, Ge Y (2019) Microalgal extracellular polymeric substances and their interactions with metal (loid) s: A review. Crit Rev Environ Sci Technol 49:1769\u20131802. https:\/\/doi.org\/10.1080\/10643389.2019.1583052","journal-title":"Crit Rev Environ Sci Technol"},{"key":"5294_CR40","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.scitotenv.2015.07.160","volume":"537","author":"J Nimptsch","year":"2015","unstructured":"Nimptsch J, Woelfl S, Osorio S, Valenzuela J, Ebersbach P, Von Tuempling W, Palma R, Encina F, Figueroa D, Kamjunke N, Graeber D (2015) Tracing dissolved organic matter (DOM) from land-based aquaculture systems in North Patagonian streams. Sci Total Environ 537:129\u2013138. https:\/\/doi.org\/10.1016\/j.scitotenv.2015.07.160","journal-title":"Sci Total Environ"},{"key":"5294_CR41","doi-asserted-by":"publisher","first-page":"10412","DOI":"10.1080\/21655979.2022.2056823","volume":"13","author":"RK Oruganti","year":"2022","unstructured":"Oruganti RK, Katam K, Show PL, Gadhamshetty V, Upadhyayula VKK, Bhattacharyya D (2022) A comprehensive review on the use of algal-bacterial systems for wastewater treatment with emphasis on nutrient and micropollutant removal. Bioengineered 13:10412\u201310453. https:\/\/doi.org\/10.1080\/21655979.2022.2056823","journal-title":"Bioengineered"},{"key":"5294_CR42","doi-asserted-by":"publisher","first-page":"116446","DOI":"10.1016\/j.envres.2023.116446","volume":"233","author":"Z Ou","year":"2023","unstructured":"Ou Z, Chen X, Wu X, Zhou C, Zhang K, Luo J, Fang F, Sun Y, Li M, Feng Q (2023) N-acyl homoserine lactone mediating initial adhesion of microalgal biofilm formation. Environ Res 233:116446. https:\/\/doi.org\/10.1016\/j.envres.2023.116446","journal-title":"Environ Res"},{"key":"5294_CR43","doi-asserted-by":"publisher","first-page":"144757","DOI":"10.1016\/j.cej.2023.144757","volume":"471","author":"S Parveen","year":"2023","unstructured":"Parveen S, Patidar SK (2023) Bacterial quorum sensing precursors N-(3-Oxododecanoyl)-L-homoserine lactone & N-(3-Hydroxyoctanoyl)-DL-homoserine lactone ameliorate algal biomass, lipids and fatty acids. Chem Eng J 471:144757. https:\/\/doi.org\/10.1016\/j.cej.2023.144757","journal-title":"Chem Eng J"},{"key":"5294_CR44","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/s00248-007-9358-3","volume":"56","author":"L Pumbwe","year":"2008","unstructured":"Pumbwe L, Skilbeck CA, Wexler HM (2008) Presence of quorum-sensing systems associated with multidrug resistance and biofilm formation in Bacteroides fragilis. Microb Ecol 56:412\u2013419. https:\/\/doi.org\/10.1007\/s00248-007-9358-3","journal-title":"Microb Ecol"},{"key":"5294_CR45","doi-asserted-by":"publisher","first-page":"3651","DOI":"10.1099\/mic.0.29226-0","volume":"152","author":"L Putthapoom","year":"2006","unstructured":"Putthapoom L, Stephen PD, Suvit L, Sumalee T, Mavis D, C\u00e1mara M, Williams P, Mongkol K (2006) Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei. Microbiology 152:3651\u20133659. https:\/\/doi.org\/10.1099\/mic.0.29226-0","journal-title":"Microbiology"},{"key":"5294_CR46","doi-asserted-by":"publisher","first-page":"10320","DOI":"10.3390\/su141610320","volume":"12","author":"C Qiu","year":"2022","unstructured":"Qiu C, Wang W, Zhang Y, Zhou G, Bi Y (2022) Response of antioxidant enzyme activities of the green microalga Chlorococcum sp. AZHB to Cu2+ and Cd2+ Stress. Sustainability 12:10320. https:\/\/doi.org\/10.3390\/su141610320","journal-title":"Sustainability"},{"key":"5294_CR47","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1016\/j.toxrep.2019.10.001","volume":"6","author":"M Rezayian","year":"2019","unstructured":"Rezayian M, Niknam V, Ebrahimzadeh H (2019) Oxidative damage and antioxidative system in algae. Toxicol Rep 6:1309\u20131313. https:\/\/doi.org\/10.1016\/j.toxrep.2019.10.001","journal-title":"Toxicol Rep"},{"key":"5294_CR48","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1016\/j.ecoenv.2009.01.003","volume":"72","author":"SE Sabatini","year":"2009","unstructured":"Sabatini SE, Ju\u00e1rez AB, Eppis MR, Bianchi L, Luquet CM, De R\u00edos MDC (2009) Oxidative stress and antioxidant defenses in two green microalgae exposed to copper. Ecotoxicol Environ Saf 72:1200\u20131206. https:\/\/doi.org\/10.1016\/j.ecoenv.2009.01.003","journal-title":"Ecotoxicol Environ Saf"},{"key":"5294_CR49","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.jphotobiol.2015.06.003","volume":"149","author":"DB Sghaier","year":"2015","unstructured":"Sghaier DB, Duarte B, Bankaji I, Ca\u00e7ador I, Sleimi N (2015) Growth, chlorophyll fluorescence and mineral nutrition in the halophyte Tamarix gallica cultivated in combined stress conditions: Arsenic and NaCl. J Photochem Photobiol B 149:204\u2013214. https:\/\/doi.org\/10.1016\/j.jphotobiol.2015.06.003","journal-title":"J Photochem Photobiol B"},{"key":"5294_CR50","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1126\/science.1170086","volume":"323","author":"T Shimoyama","year":"2009","unstructured":"Shimoyama T, Kato S, Ishii SI, Watanabe K (2009) Flagellum Mediates Symbiosis. Science 323:1574\u20131574. https:\/\/doi.org\/10.1126\/science.1170086","journal-title":"Science"},{"key":"5294_CR51","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.jwpe.2015.06.003","volume":"7","author":"MF Siddiqui","year":"2015","unstructured":"Siddiqui MF, Rzechowicz M, Harvey W, Zularisam AW, Anthony GF (2015) Quorum sensing based membrane biofouling control for water treatment: A review. J Water Process Eng 7:112\u2013122. https:\/\/doi.org\/10.1016\/j.jwpe.2015.06.003","journal-title":"J Water Process Eng"},{"key":"5294_CR53","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1021\/acschembio.8b01101","volume":"14","author":"F Stock","year":"2019","unstructured":"Stock F, Syrpas M, Van Graff S, Backx S, Blommaert L, Dow L, Stock W, Ruysbergh E, Lepetit B, Bailleul B, Sabbe K, De Kimpe N, Willems A, Kroth PG, Vardi A, Vyverman W, Mangelinckx S (2019) N-acyl homoserine lactone derived tetramic acids impair photosynthesis in Phaeodactylum tricornutum. ACS Chem Biol 14:198\u2013203. https:\/\/doi.org\/10.1021\/acschembio.8b01101","journal-title":"ACS Chem Biol"},{"key":"5294_CR52","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.3389\/fmicb.2020.01240","volume":"11","author":"F Stock","year":"2020","unstructured":"Stock F, Bilcke G, De Decker S, Osuna-Cruz CM, Van Den Berge K, Vancaester E, De Veylder L, Vandepoele K, Mangelinckx S, Vyverman W (2020) Distinctive growth and transcriptional changes of the diatom Seminavis robusta in response to quorum sensing related compounds. Front Microbiol 11:1240. https:\/\/doi.org\/10.3389\/fmicb.2020.01240","journal-title":"Front Microbiol"},{"key":"5294_CR54","doi-asserted-by":"publisher","first-page":"2206","DOI":"10.1021\/acs.est.7b05699","volume":"52","author":"X Tang","year":"2018","unstructured":"Tang X, Guo Y, Wu S, Chen L, Tao H, Liu S (2018) Metabolomics uncovers the regulatory pathway of acyl-homoserine lactones based quorum sensing in anammox consortia. Environ Sci Technol 52:2206\u20132216. https:\/\/doi.org\/10.1021\/acs.est.7b05699","journal-title":"Environ Sci Technol"},{"key":"5294_CR55","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1515\/bot.2009.012","volume":"52","author":"B Tesson","year":"2009","unstructured":"Tesson B, Gaillard C, Martin-J\u00e9z\u00e9quel V (2009) Insights into the polymorphism of the diatom Phaeodactylum tricornutum Bohlin. Bot Mar 52:104\u2013116. https:\/\/doi.org\/10.1515\/bot.2009.012","journal-title":"Bot Mar"},{"key":"5294_CR56","doi-asserted-by":"publisher","first-page":"12616","DOI":"10.1007\/s11356-014-3207-y","volume":"21","author":"E Torres","year":"2014","unstructured":"Torres E, Mera R, Herrero C, Abalde J (2014) Isotherm studies for the determination of Cd (II) ions removal capacity in living biomass of a microalga with high tolerance to cadmium toxicity. Environ Sci Pollut Res 21:12616\u201312628. https:\/\/doi.org\/10.1007\/s11356-014-3207-y","journal-title":"Environ Sci Pollut Res"},{"key":"5294_CR57","doi-asserted-by":"publisher","first-page":"117443","DOI":"10.1016\/j.envpol.2021.117443","volume":"285","author":"S Tripathi","year":"2021","unstructured":"Tripathi S, Poluri KM (2021) Heavy metal detoxification mechanisms by microalgae: Insights from transcriptomics analysis. Environ Pollut 285:117443. https:\/\/doi.org\/10.1016\/j.envpol.2021.117443","journal-title":"Environ Pollut"},{"key":"5294_CR58","doi-asserted-by":"publisher","first-page":"12645","DOI":"10.1021\/acs.est.2c00905","volume":"56","author":"H Wang","year":"2022","unstructured":"Wang H, Wu P, Zheng D, Deng L, Wang W (2022) N-Acyl-homoserine lactone (AHL)-mediated microalgal\u2013bacterial communication driving Chlorella-activated sludge bacterial biofloc formation. Environ Sci Technol 56:12645\u201312655. https:\/\/doi.org\/10.1021\/acs.est.2c00905","journal-title":"Environ Sci Technol"},{"key":"5294_CR59","doi-asserted-by":"publisher","first-page":"11900","DOI":"10.1021\/acs.est.7b03260","volume":"51","author":"UJ W\u00fcnsch","year":"2017","unstructured":"W\u00fcnsch UJ, Murphy KR, Stedmon CA (2017) The one-sample PARAFAC approach reveals molecular size distributions of fluorescent components in dissolved organic matter. Environ Sci Technol 51:11900\u201311908. https:\/\/doi.org\/10.1021\/acs.est.7b03260","journal-title":"Environ Sci Technol"},{"key":"5294_CR61","doi-asserted-by":"publisher","first-page":"2039048","DOI":"10.1080\/19490976.2022.2039048","volume":"14","author":"Y Xiao","year":"2022","unstructured":"Xiao Y, Zou H, Li J, Song T, Lv W, Wang W, Wang Z, Tao S (2022) Impact of quorum sensing signaling molecules in gram-negative bacteria on host cells: current understanding and future perspectives. Gut Microbes 14:2039048. https:\/\/doi.org\/10.1080\/19490976.2022.2039048","journal-title":"Gut Microbes"},{"key":"5294_CR60","doi-asserted-by":"publisher","first-page":"105805","DOI":"10.1016\/j.marenvres.2022.105805","volume":"183","author":"X Xiao","year":"2023","unstructured":"Xiao X, Li W, Jin M, Zhang L, Qin L, Geng W (2023) Responses and tolerance mechanisms of microalgae to heavy metal stress: A review. Mar Environ Res 183:105805. https:\/\/doi.org\/10.1016\/j.marenvres.2022.105805","journal-title":"Mar Environ Res"},{"key":"5294_CR62","doi-asserted-by":"publisher","first-page":"6506","DOI":"10.1016\/j.watres.2013.08.021","volume":"47","author":"H Xu","year":"2013","unstructured":"Xu H, Jiang H (2013) UV-induced photochemical heterogeneity of dissolved and attached organic matter associated with cyanobacterial blooms in a eutrophic freshwater lake. Water Res 47:6506\u20136515. https:\/\/doi.org\/10.1016\/j.watres.2013.08.021","journal-title":"Water Res"},{"key":"5294_CR63","doi-asserted-by":"publisher","first-page":"117627","DOI":"10.1016\/j.watres.2021.117627","volume":"204","author":"Y Xu","year":"2021","unstructured":"Xu Y, Curtis T, Dolfing J, Wu Y, Rittmann BE (2021) N-acyl-homoserine-lactones signaling as a critical control point for phosphorus entrapment by multi-species microbial aggregates. Water Res 204:117627. https:\/\/doi.org\/10.1016\/j.watres.2021.117627","journal-title":"Water Res"},{"key":"5294_CR64","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s10236-010-0365-4","volume":"61","author":"Y Yamashita","year":"2010","unstructured":"Yamashita Y, Panton A, Mahaffey C, Jaff\u00e9 R (2010) Assessing the spatial and temporal variability of dissolved organic matter in Liverpool Bay using excitation\u2013emission matrix fluorescence and parallel factor analysis. Ocean Dyn 61:569\u2013579. https:\/\/doi.org\/10.1007\/s10236-010-0365-4","journal-title":"Ocean Dyn"},{"key":"5294_CR65","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.marpolbul.2016.04.010","volume":"107","author":"C Yang","year":"2016","unstructured":"Yang C, Fang S, Chen D, Wang J, Liu F, Xia C (2016) The possible role of bacterial signal molecules N-acyl homoserine lactones in the formation of diatom-biofilm (Cylindrotheca sp). Mar Pollut Bull 107:118\u2013124. https:\/\/doi.org\/10.1016\/j.marpolbul.2016.04.010","journal-title":"Mar Pollut Bull"},{"key":"5294_CR66","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.3390\/microorganisms11071841","volume":"11","author":"C Yang","year":"2023","unstructured":"Yang C, Song G, Son J, Howard L, Yu X-Y (2023) Revealing the bacterial quorum-sensing effect on the biofilm formation of diatom Cylindrotheca sp. using multimodal Imaging. Microorganisms 11:1841. https:\/\/doi.org\/10.3390\/microorganisms11071841","journal-title":"Microorganisms"},{"key":"5294_CR67","doi-asserted-by":"publisher","first-page":"167122","DOI":"10.1016\/j.scitotenv.2023.167122","volume":"905","author":"M Ye","year":"2023","unstructured":"Ye M, Fang S, Yu Q, Chen J, Li P, Zhang C, Ge Y (2023) Copper and zinc interact significantly in their joint toxicity to Chlamydomonas reinhardtii: Insights from physiological and transcriptomic investigations. Sci Total Environ 905:167122. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.167122","journal-title":"Sci Total Environ"},{"key":"5294_CR68","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/jobm.202100314","volume":"62","author":"Q Yu","year":"2021","unstructured":"Yu Q, Li P, Li B, Zhang C, Zhang C, Ge Y (2021) Effects of algal\u2013bacterial ratio on the growth and cadmium accumulation of Chlorella salina\u2013Bacillus subtilis consortia. J Basic Microbiol 62:518\u2013529. https:\/\/doi.org\/10.1002\/jobm.202100314","journal-title":"J Basic Microbiol"},{"key":"5294_CR69","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.scitotenv.2018.12.250","volume":"659","author":"B Zhang","year":"2018","unstructured":"Zhang B, Guo Y, Lens PNL, Zhang Z, Shi W, Cui F, Tay JH (2018a) Effect of light intensity on the characteristics of algal-bacterial granular sludge and the role of N-acyl-homoserine lactone in the granulation. Sci Total Environ 659:372\u2013383. https:\/\/doi.org\/10.1016\/j.scitotenv.2018.12.250","journal-title":"Sci Total Environ"},{"key":"5294_CR73","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.biortech.2018.05.045","volume":"263","author":"C Zhang","year":"2018","unstructured":"Zhang C, Li Q, Fu L, Zhou D, Crittenden JC (2018b) Quorum sensing molecules in activated sludge could trigger microalgae lipid synthesis. Bioresour Technol 263:576\u2013582. https:\/\/doi.org\/10.1016\/j.biortech.2018.05.045","journal-title":"Bioresour Technol"},{"key":"5294_CR75","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/j.jhazmat.2019.04.072","volume":"374","author":"Z Zhang","year":"2019","unstructured":"Zhang Z, Yan K, Zhang L, Wang Q, Guo R, Yan Z, Chen J (2019) A novel cadmium-containing wastewater treatment method: Bio-immobilization by microalgae cell and their mechanism. J Hazard Mater 374:420\u2013427. https:\/\/doi.org\/10.1016\/j.jhazmat.2019.04.072","journal-title":"J Hazard Mater"},{"key":"5294_CR70","doi-asserted-by":"publisher","first-page":"109563","DOI":"10.1016\/j.rser.2019.109563","volume":"118","author":"B Zhang","year":"2020","unstructured":"Zhang B, Li W, Guo Y, Zhang Z, Shi W, Cui F, Lens PNL, Tay JH (2020a) Microalgal-bacterial consortia: From interspecies interactions to biotechnological applications. Renew Sustain Energy Rev 118:109563. https:\/\/doi.org\/10.1016\/j.rser.2019.109563","journal-title":"Renew Sustain Energy Rev"},{"key":"5294_CR72","doi-asserted-by":"publisher","first-page":"101739","DOI":"10.1016\/j.jwpe.2020.101739","volume":"39","author":"C Zhang","year":"2020","unstructured":"Zhang C, Ho S-H, Li A, Fu L, Zhou D (2020b) Co-culture of Chlorella and Scenedesmus could enhance total lipid production under bacteria quorum sensing molecule stress. J Water Process Eng 39:101739. https:\/\/doi.org\/10.1016\/j.jwpe.2020.101739","journal-title":"J Water Process Eng"},{"key":"5294_CR71","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1007\/s12155-022-10405-5","volume":"41","author":"B Zhang","year":"2022","unstructured":"Zhang B, Sun W, Su Y, Ren Q, Ji Z, Zhang A (2022) Utilization of N-Acyl Homoserine Lactone-secreting bacteria in algal environment to increase biomass accumulation of Chlorella. Bioenergy Res 41:2111\u20132121. https:\/\/doi.org\/10.1007\/s12155-022-10405-5","journal-title":"Bioenergy Res"},{"key":"5294_CR74","doi-asserted-by":"publisher","first-page":"168966","DOI":"10.1016\/j.scitotenv.2023.168966","volume":"912","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Sun D, Gao W, Zhang X, Ye W, Zhang Z (2024) The metabolic mechanisms of Cd-induced hormesis in photosynthetic microalgae, Chromochloris zofingiensis. Sci Total Environ 912:168966. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.168966","journal-title":"Sci Total Environ"},{"key":"5294_CR76","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1080\/07352689.2016.1172461","volume":"35","author":"J Zhou","year":"2016","unstructured":"Zhou J, Lyu Y, Richlen M, Anderson DM, Cai Z (2016) Quorum sensing is a language of chemical signals and plays an ecological role in algal-bacterial interactions. CRC Crit Rev Plant Sci 35:81\u2013105. https:\/\/doi.org\/10.1080\/07352689.2016.1172461","journal-title":"CRC Crit Rev Plant Sci"},{"key":"5294_CR77","doi-asserted-by":"publisher","first-page":"21739","DOI":"10.1007\/s11356-021-17371-z","volume":"29","author":"Z Zhou","year":"2021","unstructured":"Zhou Z, Wei C, Liu H, Jiao Q, Li G, Zhang J, Zhang B, Jin W, Lin D, Chen G, Yang S (2021) Exogenous ascorbic acid application alleviates cadmium toxicity in seedlings of two wheat (Triticum aestivum L.) varieties by reducing cadmium uptake and enhancing antioxidative capacity. Environ Sci Pollut Res 29:21739\u201321750. https:\/\/doi.org\/10.1007\/s11356-021-17371-z","journal-title":"Environ Sci Pollut Res"},{"key":"5294_CR78","doi-asserted-by":"publisher","first-page":"112002","DOI":"10.1016\/j.marpolbul.2021.112002","volume":"164","author":"W Zhuang","year":"2021","unstructured":"Zhuang W, Zhou F (2021) Distribution, source and pollution assessment of heavy metals in the surface sediments of the Yangtze River Estuary and its adjacent East China Sea. Mar Pollut Bull 164:112002. https:\/\/doi.org\/10.1016\/j.marpolbul.2021.112002","journal-title":"Mar Pollut Bull"}],"container-title":["World Journal of Microbiology and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-026-05294-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11274-026-05294-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11274-026-05294-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:44:16Z","timestamp":1793285056000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11274-026-05294-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,28]]},"references-count":78,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["5294"],"URL":"https:\/\/doi.org\/10.1007\/s11274-026-05294-1","relation":{},"ISSN":["1573-0972"],"issn-type":[{"value":"1573-0972","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,28]]},"assertion":[{"value":"11 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"564"}}