{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T17:28:42Z","timestamp":1784654922609,"version":"3.55.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oral Radiol"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s11282-023-00701-x","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T10:01:51Z","timestamp":1690279311000},"page":"599-613","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Orofacial symptoms suggestive of malignant lesions and the role of imaging: literature review and case presentation"],"prefix":"10.1007","volume":"39","author":[{"given":"Chieko","family":"Sugawara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"701_CR1","first-page":"5","volume":"5","author":"RE Brandt","year":"2020","unstructured":"Brandt RE, Takeuchi A, Kamata H. Numb chin syndrome: diagnostic significance over 57 years and review of 550 patients in the literature worldwide. J Syndr. 2020;5:5.","journal-title":"J Syndr"},{"issue":"3","key":"701_CR2","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.tripleo.2007.12.037","volume":"106","author":"M Kalladka","year":"2008","unstructured":"Kalladka M, Proter N, Benoliel R, Czerninski R, Eliav E. Mental nerve neuropathy: patient characteristics and neurosensory changes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(3):364\u201370.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"701_CR3","first-page":"54","volume":"36","author":"MA Marinella","year":"2000","unstructured":"Marinella MA. Numb chin syndrome: a subtle clue to possible serious illness. Hosp Phys. 2000;36:54\u20136.","journal-title":"Hosp Phys"},{"key":"701_CR4","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1212\/wnl.31.10.1277","volume":"31","author":"EW Massey","year":"1981","unstructured":"Massey EW, Moore J, Schold SC. Mental neuropathy from systemic cancer. Neurology. 1981;31:1277. https:\/\/doi.org\/10.1212\/wnl.31.10.1277.","journal-title":"Neurology"},{"key":"701_CR5","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.joms.2007.12.046","volume":"66","author":"JM Sanchis","year":"2008","unstructured":"Sanchis JM, Bag\u00e1n JV, Murillo J, D\u00edaz JM, Poveda R, Jim\u00e9nez Y. Mental neuropathy as a manifestation associated with malignant processes: its significance in relation to patient survival. J Oral Maxillofac Surg. 2008;66:995\u20138. https:\/\/doi.org\/10.1016\/j.joms.2007.12.046.","journal-title":"J Oral Maxillofac Surg"},{"key":"701_CR6","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/s0266-4356(02)00301-7","volume":"41","author":"RIF van der Waal","year":"2003","unstructured":"van der Waal RIF, Buter J, van der Waal I. Oral metastases: report of 24 cases. Br J Oral Maxillofac Surg. 2003;41:3\u20136. https:\/\/doi.org\/10.1016\/s0266-4356(02)00301-7.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"701_CR7","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1600-0714.1994.tb00072.x","volume":"23","author":"A Hirshberg","year":"1994","unstructured":"Hirshberg A, Leibovich P, Buchner A. Metastatic tumors to the jawbones: analysis of 390 cases. J Oral Pathol Med. 1994;23:337\u201341. https:\/\/doi.org\/10.1111\/j.1600-0714.1994.tb00072.x.","journal-title":"J Oral Pathol Med"},{"key":"701_CR8","doi-asserted-by":"publisher","first-page":"e21","DOI":"10.1016\/j.tripleo.2010.02.031","volume":"110","author":"ALD Kruse","year":"2010","unstructured":"Kruse ALD, Luebbers HT, Obwegeser JA, Edelmann L, Graetz KW. Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and 3 additional cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:e21\u20138. https:\/\/doi.org\/10.1016\/j.tripleo.2010.02.031.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"b67","key":"701_CR9","first-page":"1","volume":"77","author":"T Daley","year":"2011","unstructured":"Daley T, Darling MR. Metastases to the mouth and jaws: a contemporary Canadian experience. J Can Dent Assoc. 2011;77(b67):1\u20137.","journal-title":"J Can Dent Assoc."},{"key":"701_CR10","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/1477-7819-4-52","volume":"4","author":"RK Baskaran","year":"2006","unstructured":"Baskaran RK, Smith M. Numb chin syndrome\u2013a reflection of systemic malignancy. World J Surg Oncol. 2006;4:52.","journal-title":"World J Surg Oncol"},{"key":"701_CR11","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/j.beha.2005.01.024","volume":"18","author":"A Dispenzieri","year":"2005","unstructured":"Dispenzieri A, Kyle RA. Neurological aspects of multiple myeloma and related disorders. Best Pract Res Clin Haematol. 2005;18:673\u201388. https:\/\/doi.org\/10.1016\/j.beha.2005.01.024.","journal-title":"Best Pract Res Clin Haematol"},{"key":"701_CR12","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1001\/archneur.1985.04210090068018","volume":"42","author":"PJ Jannetta","year":"1985","unstructured":"Jannetta PJ. Microsurgical management of trigeminal neuralgia. Arch Neurol. 1985;42:800. https:\/\/doi.org\/10.1001\/archneur.1985.04210090068018.","journal-title":"Arch Neurol"},{"key":"701_CR13","doi-asserted-by":"publisher","first-page":"202","DOI":"10.14219\/jada.archive.2007.0137","volume":"138","author":"AW Stowell","year":"2007","unstructured":"Stowell AW, Gatchel RJ, Wildenstein L. Cost-effectiveness of treatments for temporomandibular disorders: biopsychosocial intervention versus treatment as usual. J Am Dent Assoc. 2007;138:202\u20138. https:\/\/doi.org\/10.14219\/jada.archive.2007.0137.","journal-title":"J Am Dent Assoc"},{"key":"701_CR14","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1159\/000101971","volume":"15","author":"MH Steenks","year":"2007","unstructured":"Steenks MH, Hugger A, Wijer A. Painful arthrogenous temporomandibular disorders. The PUZZLE Orofac Pain. 2007;15:124\u201352.","journal-title":"The PUZZLE Orofac Pain"},{"key":"701_CR15","unstructured":"Kino K. (2010) Guidelines of initial treatment practice for patients with temporomandibular disorders: about stabilization splint treatment for temporomandibular disorder patients with masticatory muscle pain. General dentist edition; https:\/\/www.kokuhoken.or.jp\/exterior\/jstmj\/file\/guideline_TMJ_patient.pdf (in Japanese)."},{"key":"701_CR16","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.jdsr.2013.05.002","volume":"49","author":"H Yuasa","year":"2013","unstructured":"Yuasa H, Kino K, Kubota E, Kakudo K, Sugisaki M, Nishiyama A, et al. Primary treatment of temporomandibular disorders: the Japanese society for the temporomandibular joint evidence-based clinical practice guidelines 2nd edition. Jpn Dent Sci Rev. 2013;49:89\u201398. https:\/\/doi.org\/10.1016\/j.jdsr.2013.05.002.","journal-title":"Jpn Dent Sci Rev"},{"key":"701_CR17","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10006-010-0254-5","volume":"16","author":"M Frei","year":"2012","unstructured":"Frei M, Dubach P, Reichart PA, Schmitt AM, Mueller-Garamv\u00f6lgyi E, Bornstein MM. Diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin \u2018double-hit\u2019 lymphoma: report of a case. Oral Maxillofac Surg. 2012;16:69\u201374. https:\/\/doi.org\/10.1007\/s10006-010-0254-5.","journal-title":"Oral Maxillofac Surg"},{"key":"701_CR18","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/0030-4220(79)90127-0","volume":"47","author":"P Blok","year":"1979","unstructured":"Blok P, van Delden L, van der Waal I. Non-Hodgkin\u2019s lymphoma of the hard palate. Oral Surg Oral Med Oral Pathol. 1979;47:445\u201352. https:\/\/doi.org\/10.1016\/0030-4220(79)90127-0.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"701_CR19","doi-asserted-by":"publisher","first-page":"755","DOI":"10.4103\/0973-029X.44586","volume":"109","author":"R Jayakrishnan","year":"2011","unstructured":"Jayakrishnan R, Thomas G, Kumar A, Nair RA, Mathews S. Non-Hodgkin\u2019s lymphoma of the hard palate. J Indian Med Assoc. 2011;109:755\u20136. https:\/\/doi.org\/10.4103\/0973-029X.44586.","journal-title":"J Indian Med Assoc"},{"key":"701_CR20","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.tripleo.2007.02.019","volume":"105","author":"S Kemp","year":"2008","unstructured":"Kemp S, Gallagher G, Kabani S, Noonan V, O\u2019Hara C. Oral non-Hodgkin\u2019s lymphoma: review of the literature and World Health Organization classification with reference to 40 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:194\u2013201. https:\/\/doi.org\/10.1016\/j.tripleo.2007.02.019.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"701_CR21","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/j.oooo.2012.06.004","volume":"114","author":"C Sugawara","year":"2012","unstructured":"Sugawara C, Takahashi A, Kubo M, Otsuka H, Ishimaru N, Miyamoto Y, et al. Preoperative evaluation of patients with squamous cell carcinoma of the oral cavity: fluorine-18 fluorodeoxyglucose positron emission tomography\/computed tomography and ultrasonography versus histopathology. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:516\u201325. https:\/\/doi.org\/10.1016\/j.oooo.2012.06.004.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"701_CR22","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1102\/1470-7330.2008.0006","volume":"8","author":"AT Ahuja","year":"2008","unstructured":"Ahuja AT, Ying M, Ho SY, Antonio G, Lee YP, King AD, et al. Ultrasound of malignant cervical lymph nodes. Cancer Imaging. 2008;8:48\u201356. https:\/\/doi.org\/10.1102\/1470-7330.2008.0006.","journal-title":"Cancer Imaging"},{"key":"701_CR23","doi-asserted-by":"publisher","first-page":"546","DOI":"10.3950\/jibiinkoka.115.546","volume":"115","author":"H Uchimizu","year":"2012","unstructured":"Uchimizu H, Kobayashi T, Mori E, Yamada Y, Yanagi K. A 5-year study of patients with neck lymphadenopathy. Nihon Jibiinkoka Gakkai Kaiho. 2012;115:546\u201351. https:\/\/doi.org\/10.3950\/jibiinkoka.115.546. ((in Japanese)).","journal-title":"Nihon Jibiinkoka Gakkai Kaiho"},{"key":"701_CR24","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/1471-2482-14-110","volume":"14","author":"J Chen","year":"2014","unstructured":"Chen J, Wu S, Zheng X, Pan J, Zhu K, Chen Y, et al. Cervical lymph node metastasis classified as regional nodal staging in thoracic esophageal squamous cell carcinoma after radical esophagectomy and three-field lymph node dissection. BMC Surg. 2014;14:110. https:\/\/doi.org\/10.1186\/1471-2482-14-110.","journal-title":"BMC Surg"},{"key":"701_CR25","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1111\/j.1447-073x.2005.00114.x","volume":"80","author":"M Mizutani","year":"2005","unstructured":"Mizutani M, Nawata SI, Hirai I, Murakami G, Kimura W. Anatomy and histology of Virchow\u2019s node. Anat Sci Int. 2005;80:193\u20138. https:\/\/doi.org\/10.1111\/j.1447-073x.2005.00114.x.","journal-title":"Anat Sci Int"},{"key":"701_CR26","doi-asserted-by":"publisher","first-page":"e2018053","DOI":"10.4322\/acr.2018.053","volume":"9","author":"MJ Zdilla","year":"2019","unstructured":"Zdilla MJ, Aldawood AM, Plata A, Vos JA, Lambert HW. Troisier sign and Virchow node: the anatomy and pathology of pulmonary adenocarcinoma metastasis to a supraclavicular lymph node. Autops Case Rep. 2019;9:e2018053. https:\/\/doi.org\/10.4322\/acr.2018.053.","journal-title":"Autops Case Rep"},{"key":"701_CR27","doi-asserted-by":"publisher","first-page":"913","DOI":"10.3390\/cancers14040913","volume":"14","author":"M Wedin","year":"2022","unstructured":"Wedin M, Tsoli M, Wallin G, Janson ET, Koumarianou A, Kaltsas G, et al. Heterogeneity of small intestinal neuroendocrine tumors metastasis: biologic patterns of a series with Virchow\u2019s node involvement. Cancers. 2022;14:913. https:\/\/doi.org\/10.3390\/cancers14040913.","journal-title":"Cancers"},{"key":"701_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.105720","volume":"81","author":"Y Oukessou","year":"2021","unstructured":"Oukessou Y, Hammouda Y, Bouhmadi EIK, Abada RL, Roubal M, Mahtar M. Supraclavicular lymph node metastases from distant primary tumors: case reports and review of the literature. Int J Surg Case Rep. 2021;81: 105720.","journal-title":"Int J Surg Case Rep"},{"key":"701_CR29","doi-asserted-by":"publisher","first-page":"20150362","DOI":"10.1259\/dmfr.20150362","volume":"45","author":"C Sugawara","year":"2016","unstructured":"Sugawara C, Takahashi A, Kawano F, Kudo Y, Ishimaru N, Miyamoto Y. Intraoral ultrasonography of tongue mass lesions. Dentomaxillofac Radiol. 2016;45:20150362. https:\/\/doi.org\/10.1259\/dmfr.20150362.","journal-title":"Dentomaxillofac Radiol"},{"key":"701_CR30","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1177\/000348940511400110","volume":"114","author":"KJ Cho","year":"2005","unstructured":"Cho KJ, Cho SG, Lee DH. Natural killer T-cell lymphoma of the tongue. Ann Otol Rhinol Laryngol. 2005;114:55\u20137. https:\/\/doi.org\/10.1177\/000348940511400110.","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"701_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1758-3284-3-1","volume":"3","author":"F Inchingolo","year":"2011","unstructured":"Inchingolo F, Tatullo M, Abenavoli FM, Marrelli M, Inchingolo AD, Inchingolo AM, et al. Non-Hodgkin lymphoma affecting the tongue: unusual intra-oral location. Head Neck Oncol. 2011;3:1. https:\/\/doi.org\/10.1186\/1758-3284-3-1.","journal-title":"Head Neck Oncol"},{"key":"701_CR32","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1111\/j.1600-0714.1984.tb01465.x","volume":"13","author":"N Van der Wal","year":"1984","unstructured":"Van der Wal N, Henzen-Logmans S, Van Der Kwast WAM, Van Der Waal I. Amyloidosis of the tongue: a clinical and postmortem study. J Oral Pathol. 1984;13:632\u20139. https:\/\/doi.org\/10.1111\/j.1600-0714.1984.tb01465.x.","journal-title":"J Oral Pathol"},{"key":"701_CR33","doi-asserted-by":"publisher","first-page":"258","DOI":"10.3892\/mco.2020.1972","volume":"12","author":"G Musat","year":"2020","unstructured":"Musat G, Evsei A, Calina D, Docea AO, Doukas SG, Vageli DP, et al. Rare amyloidoma of the tongue base: a case report and review of the literature. Mol Clin Oncol. 2020;12:258\u201362. https:\/\/doi.org\/10.3892\/mco.2020.1972.","journal-title":"Mol Clin Oncol"},{"key":"701_CR34","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.bjorl.2020.11.011","volume":"88","author":"DWVN Dissanayaka","year":"2022","unstructured":"Dissanayaka DWVN, Bandara HMMR, Sabesan T, Mohomed YS, Siriwardena BSMS. Oral manifestations of systemic amyloidosis, an aid to diagnosis of multiple myeloma-report of two cases. Braz J Otorhinolaryngo. 2022;88:146\u20139. https:\/\/doi.org\/10.1016\/j.bjorl.2020.11.011.","journal-title":"Braz J Otorhinolaryngo"},{"key":"701_CR35","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/0030-4220(94)90272-0","volume":"77","author":"EI Reinish","year":"1994","unstructured":"Reinish EI, Raviv M, Srolovitz H, Gornitsky M. Tongue, primary amyloidosis, and multiple myeloma. Oral Surg Oral Med Oral Pathol. 1994;77:121\u20135. https:\/\/doi.org\/10.1016\/0030-4220(94)90272-0.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"701_CR36","doi-asserted-by":"publisher","first-page":"464","DOI":"10.3816\/CLML.2010.n.080","volume":"10","author":"G Talamo","year":"2010","unstructured":"Talamo G, Farooq U, Zangari M, Liao J, Dolloff NG, Loughran TP, et al. Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma. Clin Lymphoma Myeloma Leuk. 2010;10:464\u20138. https:\/\/doi.org\/10.3816\/CLML.2010.n.080.","journal-title":"Clin Lymphoma Myeloma Leuk"}],"container-title":["Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11282-023-00701-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11282-023-00701-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11282-023-00701-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T19:10:22Z","timestamp":1694805022000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11282-023-00701-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,25]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["701"],"URL":"https:\/\/doi.org\/10.1007\/s11282-023-00701-x","relation":{},"ISSN":["0911-6028","1613-9674"],"issn-type":[{"value":"0911-6028","type":"print"},{"value":"1613-9674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,25]]},"assertion":[{"value":"21 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest associated with this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study is not related to human use, but uses real patient data. This study was approved by the author\u2019s institution's policy.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The photographs\/radiographic images in the article were provided consent for the patients used to be published.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}