{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:08:38Z","timestamp":1773220118831,"version":"3.50.1"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Fondi Ateneo University of Florence to EC","award":["RICATEN-2024"],"award-info":[{"award-number":["RICATEN-2024"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Purinergic Signalling"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1007\/s11302-025-10079-6","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T08:39:32Z","timestamp":1744101572000},"page":"1025-1027","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A new approach to psoriasis therapy: photoswitchable A3 adenosine receptor activation"],"prefix":"10.1007","volume":"21","author":[{"given":"Federica","family":"Cherchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Coppi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"10079_CR1","doi-asserted-by":"publisher","first-page":"105731","DOI":"10.1016\/J.PHRS.2021.105731","volume":"170","author":"M L\u00f3pez-Cano","year":"2021","unstructured":"L\u00f3pez-Cano M, Filgaira I, Nolen EG et al (2021) Optical control of adenosine A3 receptor function in psoriasis. Pharmacol Res 170:105731. https:\/\/doi.org\/10.1016\/J.PHRS.2021.105731","journal-title":"Pharmacol Res"},{"key":"10079_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1124\/pr.110.003285","volume":"63","author":"BB Fredholm","year":"2011","unstructured":"Fredholm BB, Ijzerman AP, Jacobson KA et al (2011) International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors\u2013An Update. Pharmacol Rev 63:1\u201334. https:\/\/doi.org\/10.1124\/pr.110.003285","journal-title":"Pharmacol Rev"},{"key":"10079_CR3","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1111\/JDV.19811","volume":"38","author":"KA Papp","year":"2024","unstructured":"Papp KA, Beyska-Rizova S, Gantcheva ML et al (2024) Efficacy and safety of piclidenoson in plaque psoriasis: results from a randomized phase 3 clinical trial (COMFORT-1). J Eur Acad Dermatol Venereol 38:1112\u20131120. https:\/\/doi.org\/10.1111\/JDV.19811","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10079_CR4","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1016\/J.BBAMEM.2010.12.017","volume":"1808","author":"CE M\u00fcller","year":"2011","unstructured":"M\u00fcller CE, Jacobson KA (2011) Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim Biophys Acta 1808:1290\u20131308. https:\/\/doi.org\/10.1016\/J.BBAMEM.2010.12.017","journal-title":"Biochim Biophys Acta"},{"key":"10079_CR5","doi-asserted-by":"publisher","first-page":"2178","DOI":"10.1021\/JA413063E\/ASSET\/IMAGES\/LARGE\/JA-2013-13063E_0015.JPEG","volume":"136","author":"WA Velema","year":"2014","unstructured":"Velema WA, Szymanski W, Feringa BL (2014) Photopharmacology: beyond proof of principle. J Am Chem Soc 136:2178\u20132191. https:\/\/doi.org\/10.1021\/JA413063E\/ASSET\/IMAGES\/LARGE\/JA-2013-13063E_0015.JPEG","journal-title":"J Am Chem Soc"},{"key":"10079_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/ncomms12221","volume":"7","author":"M Izquierdo-Serra","year":"2016","unstructured":"Izquierdo-Serra M, Bautista-Barrufet A, Trapero A et al (2016) (2016) Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches. Nature Commun 7:1\u201312. https:\/\/doi.org\/10.1038\/ncomms12221","journal-title":"Nature Commun"},{"key":"10079_CR7","doi-asserted-by":"publisher","first-page":"102196","DOI":"10.1016\/J.COPH.2022.102196","volume":"63","author":"J Broichhagen","year":"2022","unstructured":"Broichhagen J, Levitz J (2022) Advances in tethered photopharmacology for precise optical control of signaling proteins. Curr Opin Pharmacol 63:102196. https:\/\/doi.org\/10.1016\/J.COPH.2022.102196","journal-title":"Curr Opin Pharmacol"},{"key":"10079_CR8","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/J.CONB.2011.02.010","volume":"21","author":"AV Kravitz","year":"2011","unstructured":"Kravitz AV, Kreitzer AC (2011) Optogenetic manipulation of neural circuitry in vivo. Curr Opin Neurobiol 21:433\u2013439. https:\/\/doi.org\/10.1016\/J.CONB.2011.02.010","journal-title":"Curr Opin Neurobiol"},{"key":"10079_CR9","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.3390\/MOLECULES27061890","volume":"27","author":"E Coppi","year":"2022","unstructured":"Coppi E, Cherchi F, Venturini M et al (2022) Therapeutic potential of highly selective A 3 adenosine receptor ligands in the central and peripheral nervous system. Molecules 27:1890. https:\/\/doi.org\/10.3390\/MOLECULES27061890","journal-title":"Molecules"}],"container-title":["Purinergic Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11302-025-10079-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11302-025-10079-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11302-025-10079-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T02:45:57Z","timestamp":1762569957000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11302-025-10079-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,7]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10079"],"URL":"https:\/\/doi.org\/10.1007\/s11302-025-10079-6","relation":{},"ISSN":["1573-9538","1573-9546"],"issn-type":[{"value":"1573-9538","type":"print"},{"value":"1573-9546","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,7]]},"assertion":[{"value":"5 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}]}}