{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:13:37Z","timestamp":1773418417406,"version":"3.50.1"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2014,7,14]],"date-time":"2014-07-14T00:00:00Z","timestamp":1405296000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Metabolomics"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1007\/s11306-014-0695-1","type":"journal-article","created":{"date-parts":[[2014,7,13]],"date-time":"2014-07-13T13:05:28Z","timestamp":1405256728000},"page":"312-322","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes"],"prefix":"10.1007","volume":"11","author":[{"given":"Ranjan","family":"Banerjee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn","family":"Spaniel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan T.","family":"Quintana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongjing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James R.","family":"Bain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher B.","family":"Newgard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Muehlbauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monte S.","family":"Willis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,7,14]]},"reference":[{"key":"695_CR1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/01.RES.76.2.261","volume":"76","author":"KE Anderson","year":"1995","unstructured":"Anderson, K. E., Dart, A. M., & Woodcock, E. A. (1995). Inositol phosphate release and metabolism during myocardial ischemia and reperfusion in rat heart. Circulation Research, 76, 261\u2013268.","journal-title":"Circulation Research"},{"key":"695_CR2","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0167-5273(82)90052-3","volume":"2","author":"J Azuma","year":"1982","unstructured":"Azuma, J., et al. (1982). Taurine for treatment of congestive heart failure. International Journal of Cardiology, 2, 303\u2013304.","journal-title":"International Journal of Cardiology"},{"key":"695_CR3","first-page":"398","volume":"5","author":"J Azuma","year":"1983","unstructured":"Azuma, J., et al. (1983). Therapy of congestive heart failure with orally administered taurine. Clinical Therapeutics, 5, 398\u2013408.","journal-title":"Clinical Therapeutics"},{"key":"695_CR4","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/clc.4960080507","volume":"8","author":"J Azuma","year":"1985","unstructured":"Azuma, J., et al. (1985). Therapeutic effect of taurine in congestive heart failure: a double-blind crossover trial. Clinical Cardiology, 8, 276\u2013282.","journal-title":"Clinical Cardiology"},{"key":"695_CR5","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.2337\/db09-0580","volume":"58","author":"JR Bain","year":"2009","unstructured":"Bain, J. R., Stevens, R. D., Wenner, B. R., Ilkayeva, O., Muoio, D. M., & Newgard, C. B. (2009). Metabolomics applied to diabetes research: Moving from information to knowledge. Diabetes, 58, 2429\u20132443. doi: 10.2337\/db09-0580 .","journal-title":"Diabetes"},{"key":"695_CR6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/361315a0","volume":"361","author":"MJ Berridge","year":"1993","unstructured":"Berridge, M. J. (1993). Inositol trisphosphate and calcium signalling. Nature, 361, 315\u2013325. doi: 10.1038\/361315a0 .","journal-title":"Nature"},{"key":"695_CR7","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1126\/science.1065874","volume":"294","author":"SC Bodine","year":"2001","unstructured":"Bodine, S. C., et al. (2001). Identification of ubiquitin ligases required for skeletal muscle atrophy. Science, 294, 1704\u20131708. doi: 10.1126\/science.1065874 .","journal-title":"Science"},{"key":"695_CR8","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1006\/jmbi.2001.4448","volume":"306","author":"T Centner","year":"2001","unstructured":"Centner, T., et al. (2001). Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. Journal of Molecular Biology, 306, 717\u2013726. doi: 10.1006\/jmbi.2001.4448 .","journal-title":"Journal of Molecular Biology"},{"key":"695_CR9","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0024-3205(77)90261-2","volume":"21","author":"MF Crass 3rd","year":"1977","unstructured":"Crass, M. F, 3rd, & Lombardini, J. B. (1977). Loss of cardiac muscle taurine after acute left ventricular ischemia. Life Sciences, 21, 951\u2013958.","journal-title":"Life Sciences"},{"key":"695_CR10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/978-1-4614-6130-2_31","volume":"775","author":"A Idrissi El","year":"2013","unstructured":"El Idrissi, A., Okeke, E., Yan, X., Sidime, F., & Neuwirth, L. S. (2013). Taurine regulation of blood pressure and vasoactivity. Advances in Experimental Medicine and Biology, 775, 407\u2013425. doi: 10.1007\/978-1-4614-6130-2_31 .","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"695_CR11","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1365-313X.2007.03387.x","volume":"53","author":"O Fiehn","year":"2008","unstructured":"Fiehn, O., et al. (2008). Quality control for plant metabolomics: Reporting MSI-compliant studies. Plant journal, 53, 691\u2013704. doi: 10.1111\/j.1365-313X.2007.03387.x .","journal-title":"Plant journal"},{"key":"695_CR12","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1172\/JCI32827","volume":"117","author":"J Fielitz","year":"2007","unstructured":"Fielitz, J., et al. (2007a). Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. The Journal of Clinical Investigation, 117, 2486\u20132495. doi: 10.1172\/JCI32827 .","journal-title":"The Journal of Clinical Investigation"},{"key":"695_CR13","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1073\/pnas.0611726104","volume":"104","author":"J Fielitz","year":"2007","unstructured":"Fielitz, J., et al. (2007b). Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction. Proceedings of the National Academy of Sciences United States of America, 104, 4377\u20134382. doi: 10.1073\/pnas.0611726104 .","journal-title":"Proceedings of the National Academy of Sciences United States of America"},{"key":"695_CR14","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s10545-006-0228-9","volume":"29","author":"DM Frazier","year":"2006","unstructured":"Frazier, D. M., et al. (2006). The tandem mass spectrometry newborn screening experience in North Carolina: 1997\u20132005. Journal of Inherited Metabolic Disease, 29, 76\u201385. doi: 10.1007\/s10545-006-0228-9 .","journal-title":"Journal of Inherited Metabolic Disease"},{"key":"695_CR15","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/cvr\/cvq258","volume":"88","author":"A Gonzalez-Loyola","year":"2010","unstructured":"Gonzalez-Loyola, A., & Barba, I. (2010). Mitochondrial metabolism revisited: A route to cardioprotection. Cardiovascular Research, 88, 209\u2013210. doi: 10.1093\/cvr\/cvq258 .","journal-title":"Cardiovascular Research"},{"key":"695_CR16","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.freeradbiomed.2004.06.041","volume":"37","author":"VH Guaiquil","year":"2004","unstructured":"Guaiquil, V. H., Golde, D. W., Beckles, D. L., Mascareno, E. J., & Siddiqui, M. A. (2004). Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts. Free Radical Biology and Medicine, 37, 1419\u20131429. doi: 10.1016\/j.freeradbiomed.2004.06.041 .","journal-title":"Free Radical Biology and Medicine"},{"key":"695_CR17","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/(SICI)1097-0231(19990228)13:4<279::AID-RCM478>3.0.CO;2-I","volume":"13","author":"JM Halket","year":"1999","unstructured":"Halket, J. M., Przyborowska, A., Stein, S. E., Mallard, W. G., Down, S., & Chalmers, R. A. (1999). Deconvolution gas chromatography\/mass spectrometry of urinary organic acids\u2013potential for pattern recognition and automated identification of metabolic disorders. Rapid Communications in Mass Spectrometry, 13, 279\u2013284. doi: 10.1002\/(SICI)1097-0231(19990228)13:4<279:AID-RCM478>3.0.CO;2-I .","journal-title":"Rapid Communications in Mass Spectrometry"},{"key":"695_CR18","doi-asserted-by":"crossref","first-page":"11720","DOI":"10.1073\/pnas.171325998","volume":"98","author":"J Huang","year":"2001","unstructured":"Huang, J., et al. (2001). Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. Proceedings of the National Academy of Sciences United States of America, 98, 11720\u201311724. doi: 10.1073\/pnas.171325998 .","journal-title":"Proceedings of the National Academy of Sciences United States of America"},{"key":"695_CR19","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1126\/science.184.4142.1187","volume":"184","author":"R Huxtable","year":"1974","unstructured":"Huxtable, R., & Bressler, R. (1974). Taurine concentrations in congestive heart failure. Science, 184, 1187\u20131188.","journal-title":"Science"},{"key":"695_CR20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00726-013-1507-z","volume":"46","author":"T Ito","year":"2014","unstructured":"Ito, T., Schaffer, S., & Azuma, J. (2014). The effect of taurine on chronic heart failure: Actions of taurine against catecholamine and angiotensin II. Amino Acids, 46, 111\u2013119. doi: 10.1007\/s00726-013-1507-z .","journal-title":"Amino Acids"},{"key":"695_CR21","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.clinbiochem.2013.04.008","volume":"46","author":"OY Kim","year":"2013","unstructured":"Kim, O. Y., Jung, Y. S., Cho, Y., Chung, J. H., Hwang, G. S., & Shin, M. J. (2013). Altered heart and kidney phospholipid fatty acid composition are associated with cardiac hypertrophy in hypertensive rats. Clinical Biochemistry, 46, 1111\u20131117. doi: 10.1016\/j.clinbiochem.2013.04.008 .","journal-title":"Clinical Biochemistry"},{"key":"695_CR22","doi-asserted-by":"crossref","first-page":"10038","DOI":"10.1021\/ac9019522","volume":"81","author":"T Kind","year":"2009","unstructured":"Kind, T., et al. (2009). FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography\/mass spectrometry. Analytical Chemistry, 81, 10038\u201310048. doi: 10.1021\/ac9019522 .","journal-title":"Analytical Chemistry"},{"issue":"8","key":"695_CR23","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1093\/bioinformatics\/bti236","volume":"21","author":"J Kopka","year":"2005","unstructured":"Kopka, J., Schauer, N., Krueger, S., Birkemeyer, C., Usadel, B., Bergmueller, E., et al. (2005). GMD@CSB.DB: The golm metabolome database. Bioinformatics, 21(8), 1635\u20131638.","journal-title":"Bioinformatics"},{"key":"695_CR24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10557-005-0443-x","volume":"19","author":"C Li","year":"2005","unstructured":"Li, C., et al. (2005). Taurine may prevent diabetic rats from developing cardiomyopathy also by downregulating angiotensin II type2 receptor expression. Cardiovascular Drugs and Therapy, 19, 105\u2013112. doi: 10.1007\/s10557-005-0443-x .","journal-title":"Cardiovascular Drugs and Therapy"},{"key":"695_CR25","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.ajpath.2010.11.049","volume":"178","author":"HH Li","year":"2011","unstructured":"Li, H. H., et al. (2011). The ubiquitin ligase MuRF1 protects against cardiac ischemia\/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun. American Journal of Pathology, 178, 1043\u20131058. doi: 10.1016\/j.ajpath.2010.11.049 .","journal-title":"American Journal of Pathology"},{"key":"695_CR26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1152\/physrev.00015.2009","volume":"90","author":"GD Lopaschuk","year":"2010","unstructured":"Lopaschuk, G. D., Ussher, J. R., Folmes, C. D., Jaswal, J. S., & Stanley, W. C. (2010). Myocardial fatty acid metabolism in health and disease. Physiological Reviews, 90, 207\u2013258. doi: 10.1152\/physrev.00015.2009 .","journal-title":"Physiological Reviews"},{"key":"695_CR27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0022-3565(25)10243-7","volume":"264","author":"GD Lopaschuk","year":"1993","unstructured":"Lopaschuk, G. D., Wambolt, R. B., & Barr, R. L. (1993). An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts. Journal of Pharmacology and Experimental Therapeutics, 264, 135\u2013144.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"695_CR28","unstructured":"Mallard, W. G., Reed J. (1997). Automated Mass Spectral Deconvolution and Identification System: AMDIS User Guide. National Institute of Standards and Technology, US Department of Commerce iv, 58. http:\/\/chemdata.nist.gov\/mass-spc\/amdis\/docs\/amdis.pdf ."},{"key":"695_CR29","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0022-2828(77)80061-8","volume":"9","author":"MJ McBroom","year":"1977","unstructured":"McBroom, M. J., & Welty, J. D. (1977). Effects of taurine on heart calcium in the cardiomyopathic hamster. Journal of Molecular and Cellular Cardiology, 9, 853\u2013858.","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"695_CR30","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/cvr\/cvr051","volume":"91","author":"TT Nielsen","year":"2011","unstructured":"Nielsen, T. T., Stottrup, N. B., Lofgren, B., & Botker, H. E. (2011). Metabolic fingerprint of ischaemic cardioprotection: Importance of the malate-aspartate shuttle. Cardiovascular Research, 91, 382\u2013391. doi: 10.1093\/cvr\/cvr051 .","journal-title":"Cardiovascular Research"},{"key":"695_CR31","first-page":"2673","volume":"18","author":"H Ripps","year":"2012","unstructured":"Ripps, H., & Shen, W. (2012). Review: Taurine: A \u201cvery essential\u201d amino acid. Molecular Vision, 18, 2673\u20132686.","journal-title":"Molecular Vision"},{"key":"695_CR32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/CS20110663","volume":"124","author":"R Rodrigo","year":"2013","unstructured":"Rodrigo, R., Prieto, J. C., & Castillo, R. (2013). Cardioprotection against ischaemia\/reperfusion by vitamins C and E plus n-3 fatty acids: Molecular mechanisms and potential clinical applications. Clinical Science (Lond), 124, 1\u201315. doi: 10.1042\/CS20110663 .","journal-title":"Clinical Science (Lond)"},{"key":"695_CR33","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1365-313x.2000.00774.x","volume":"23","author":"U Roessner","year":"2000","unstructured":"Roessner, U., Wagner, C., Kopka, J., Trethewey, R. N., & Willmitzer, L. (2000). Technical advance: Simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry. Plant Journal, 23, 131\u2013142.","journal-title":"Plant Journal"},{"key":"695_CR34","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1006\/jmcc.2000.1257","volume":"32","author":"BE Rupert","year":"2000","unstructured":"Rupert, B. E., Segar, J. L., Schutte, B. C., & Scholz, T. D. (2000). Metabolic adaptation of the hypertrophied heart: Role of the malate\/aspartate and alpha-glycerophosphate shuttles. Journal of Molecular and Cellular Cardiology, 32, 2287\u20132297. doi: 10.1006\/jmcc.2000.1257 .","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"695_CR35","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.1016\/S0021-9258(19)50600-7","volume":"267","author":"M Saddik","year":"1992","unstructured":"Saddik, M., & Lopaschuk, G. D. (1992). Myocardial triglyceride turnover during reperfusion of isolated rat hearts subjected to a transient period of global ischemia. Journal of Biological Chemistry, 267, 3825\u20133831.","journal-title":"Journal of Biological Chemistry"},{"issue":"Suppl 1","key":"695_CR36","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1423-0127-17-S1-S2","volume":"17","author":"SW Schaffer","year":"2010","unstructured":"Schaffer, S. W., Jong, C. J., Ramila, K. C., & Azuma, J. (2010). Physiological roles of taurine in heart and muscle. Journal of Biomedical Science, 17(Suppl 1), S2. doi: 10.1186\/1423-0127-17-S1-S2 .","journal-title":"Journal of Biomedical Science"},{"key":"695_CR37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/jmcc.1999.1047","volume":"32","author":"TD Scholz","year":"2000","unstructured":"Scholz, T. D., TenEyck, C. J., & Schutte, B. C. (2000). Thyroid hormone regulation of the NADH shuttles in liver and cardiac mitochondria. Journal of Molecular and Cellular Cardiology, 32, 1\u201310. doi: 10.1006\/jmcc.1999.1047 .","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"695_CR38","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0735-1097(85)80166-2","volume":"6","author":"M Schwaiger","year":"1985","unstructured":"Schwaiger, M., et al. (1985). Retention and clearance of C-11 palmitic acid in ischemic and reperfused canine myocardium. Journal of the American College of Cardiology, 6, 311\u2013320.","journal-title":"Journal of the American College of Cardiology"},{"key":"695_CR39","first-page":"24","volume":"54","author":"LN Sernov","year":"1991","unstructured":"Sernov, L. N., Sokolova, O. A., & Gatsura, V. V. (1991). The antiacidotic and cardioprotective effects of fructose-1,6-diphosphate and dehydroascorbic acid. Farmakol Toksikol, 54, 24\u201326.","journal-title":"Farmakol Toksikol"},{"key":"695_CR40","doi-asserted-by":"crossref","first-page":"78R","DOI":"10.1203\/01.PDR.0000159631.63843.3E","volume":"57","author":"PS Shekhawat","year":"2005","unstructured":"Shekhawat, P. S., Matern, D., & Strauss, A. W. (2005). Fetal fatty acid oxidation disorders, their effect on maternal health and neonatal outcome: Impact of expanded newborn screening on their diagnosis and management. Pediatric Research, 57, 78R\u201386R. doi: 10.1203\/01.PDR.0000159631.63843.3E .","journal-title":"Pediatric Research"},{"key":"695_CR41","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.jacc.2009.08.012","volume":"54","author":"V Soukoulis","year":"2009","unstructured":"Soukoulis, V., et al. (2009). Micronutrient deficiencies an unmet need in heart failure. Journal of the American College of Cardiology, 54, 1660\u20131673. doi: 10.1016\/j.jacc.2009.08.012 .","journal-title":"Journal of the American College of Cardiology"},{"issue":"8","key":"695_CR42","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S1044-0305(99)00047-1","volume":"10","author":"SE Stein","year":"1999","unstructured":"Stein, S. E. (1999). An integrated method for spectrum extraction and compound identification from GC\/MS data. Journal of the American Society for Mass Spectrometry, 10(8), 770\u2013781.","journal-title":"Journal of the American Society for Mass Spectrometry"},{"key":"695_CR43","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/cvr\/cvq205","volume":"88","author":"NB Stottrup","year":"2010","unstructured":"Stottrup, N. B., et al. (2010). Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection. Cardiovascular Research, 88, 257\u2013266. doi: 10.1093\/cvr\/cvq205 .","journal-title":"Cardiovascular Research"},{"key":"695_CR44","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1021\/ac0614846","volume":"79","author":"MP Styczynski","year":"2007","unstructured":"Styczynski, M. P., Moxley, J. F., Tong, L. V., Walther, J. L., Jensen, K. L., & Stephanopoulos, G. N. (2007). Systematic identification of conserved metabolites in GC\/MS data for metabolomics and biomarker discovery. Analytical Chemistry, 79, 966\u2013973. doi: 10.1021\/ac0614846 .","journal-title":"Analytical Chemistry"},{"key":"695_CR45","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/0002-8703(86)90360-1","volume":"112","author":"K Takihara","year":"1986","unstructured":"Takihara, K., et al. (1986). Beneficial effect of taurine in rabbits with chronic congestive heart failure. American Heart Journal, 112, 1278\u20131284.","journal-title":"American Heart Journal"},{"key":"695_CR46","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1104\/pp.108.135129","volume":"150","author":"J Torabinejad","year":"2009","unstructured":"Torabinejad, J., Donahue, J. L., Gunesekera, B. N., Allen-Daniels, M. J., & Gillaspy, G. E. (2009). VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants. Plant Physiology, 150, 951\u2013961. doi: 10.1104\/pp.108.135129 .","journal-title":"Plant Physiology"},{"key":"695_CR47","doi-asserted-by":"crossref","first-page":"E668","DOI":"10.1152\/ajpendo.00151.2011","volume":"301","author":"I Ueki","year":"2011","unstructured":"Ueki, I., et al. (2011). Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide. American Journal of Physiology-Endocrinology and Metabolism, 301, E668\u2013E684. doi: 10.1152\/ajpendo.00151.2011 .","journal-title":"American Journal of Physiology-Endocrinology and Metabolism"},{"key":"695_CR48","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/01.RES.0000259559.48597.32","volume":"100","author":"MS Willis","year":"2007","unstructured":"Willis, M. S., Ike, C., Li, L., Wang, D. Z., Glass, D. J., & Patterson, C. (2007). Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circulation Research, 100, 456\u2013459. doi: 10.1161\/01.RES.0000259559.48597.32 .","journal-title":"Circulation Research"},{"key":"695_CR49","doi-asserted-by":"crossref","first-page":"H997","DOI":"10.1152\/ajpheart.00660.2008","volume":"296","author":"MS Willis","year":"2009","unstructured":"Willis, M. S., et al. (2009a). Muscle ring finger 1 mediates cardiac atrophy in vivo. American Journal of Physiology Heart and Circulatory Physiology, 296, H997\u2013H1006. doi: 10.1152\/ajpheart.00660.2008 .","journal-title":"American Journal of Physiology Heart and Circulatory Physiology"},{"key":"695_CR50","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1161\/CIRCRESAHA.109.194928","volume":"105","author":"MS Willis","year":"2009","unstructured":"Willis, M. S., et al. (2009b). Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo. Circulation Research, 105, 80\u201388. doi: 10.1161\/CIRCRESAHA.109.194928 .","journal-title":"Circulation Research"},{"key":"695_CR51","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/cbf.2969","volume":"32","author":"MS Willis","year":"2014","unstructured":"Willis, M. S., et al. (2014). Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo. Cell Biochemistry and Function, 32, 39\u201350. doi: 10.1002\/cbf.2969 .","journal-title":"Cell Biochemistry and Function"},{"key":"695_CR52","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/sj.emboj.7601952","volume":"27","author":"CC Witt","year":"2008","unstructured":"Witt, C. C., Witt, S. H., Lerche, S., Labeit, D., Back, W., & Labeit, S. (2008). Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2. EMBO Journal, 27, 350\u2013360. doi: 10.1038\/sj.emboj.7601952 .","journal-title":"EMBO Journal"},{"key":"695_CR53","doi-asserted-by":"crossref","first-page":"W127","DOI":"10.1093\/nar\/gks374","volume":"40","author":"J Xia","year":"2012","unstructured":"Xia, J., Mandal, R., Sinelnikov, I. V., Broadhurst, D., & Wishart, D. S. (2012). MetaboAnalyst 2.0\u2013a comprehensive server for metabolomic data analysis. Nucleic Acids Research, 40, W127\u2013W133. doi: 10.1093\/nar\/gks374 .","journal-title":"Nucleic Acids Research"},{"key":"695_CR54","doi-asserted-by":"crossref","first-page":"W652","DOI":"10.1093\/nar\/gkp356","volume":"37","author":"J Xia","year":"2009","unstructured":"Xia, J., Psychogios, N., Young, N., & Wishart, D. S. (2009). MetaboAnalyst: A web server for metabolomic data analysis and interpretation. Nucleic Acids Research, 37, W652\u2013W660. doi: 10.1093\/nar\/gkp356 .","journal-title":"Nucleic Acids Research"}],"container-title":["Metabolomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11306-014-0695-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11306-014-0695-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11306-014-0695-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T19:45:01Z","timestamp":1746301501000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11306-014-0695-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,14]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["695"],"URL":"https:\/\/doi.org\/10.1007\/s11306-014-0695-1","relation":{},"ISSN":["1573-3882","1573-3890"],"issn-type":[{"value":"1573-3882","type":"print"},{"value":"1573-3890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,14]]}}}