{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T05:12:57Z","timestamp":1779167577025,"version":"3.51.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:00:00Z","timestamp":1709942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071671"],"award-info":[{"award-number":["82071671"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Metabolomics"],"DOI":"10.1007\/s11306-024-02105-2","type":"journal-article","created":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T13:01:22Z","timestamp":1709989282000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparisons of different extraction methods and solvents for saliva samples"],"prefix":"10.1007","volume":"20","author":[{"given":"Lingli","family":"Fang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiming","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,9]]},"reference":[{"key":"2105_CR1","doi-asserted-by":"publisher","unstructured":"Al-Salhi, R., Monfort, C., Bonvallot, N., & David, A. (2022). Analytical strategies to profile the internal chemical exposome and the metabolome of human placenta. Anal Chim Acta, 1219, 339983. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35715127. https:\/\/doi.org\/10.1016\/j.aca.2022.339983.","DOI":"10.1016\/j.aca.2022.339983"},{"key":"2105_CR2","doi-asserted-by":"publisher","unstructured":"Alvarez-Sanchez, B., Priego-Capote, F., & de Luque, M. D. (2012). Study of sample preparation for metabolomic profiling of human saliva by liquid chromatography-time of flight\/mass spectrometry. J Chromatogr A, 1248, 178\u2013181. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22727327. https:\/\/doi.org\/10.1016\/j.chroma.2012.05.029.","DOI":"10.1016\/j.chroma.2012.05.029"},{"key":"2105_CR3","doi-asserted-by":"publisher","unstructured":"Bao, J., Li, L., Zhang, Y., Wang, M., Chen, F., Ge, S., & Yan, F. (2022). Periodontitis may induce gut microbiota dysbiosis via salivary microbiota. Int J Oral Sci, 14(1), 32. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35732628. https:\/\/doi.org\/10.1038\/s41368-022-00183-3.","DOI":"10.1038\/s41368-022-00183-3"},{"key":"2105_CR4","doi-asserted-by":"publisher","unstructured":"Castillo-Peinado, L. S., Lopez-Bascon, M. A., Mena-Bravo, A., Luque de Castro, M. D., & Priego-Capote, F. (2019). Determination of primary fatty acid amides in different biological fluids by LC-MS\/MS in MRM mode with synthetic deuterated standards: Influence of biofluid matrix on sample preparation. Talanta, 193, 29\u201336. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30368294. https:\/\/doi.org\/10.1016\/j.talanta.2018.09.088.","DOI":"10.1016\/j.talanta.2018.09.088"},{"key":"2105_CR5","doi-asserted-by":"publisher","unstructured":"Chen, C. J., Lee, D. Y., Yu, J., Lin, Y. N., & Lin, T. M. (2022). Recent advances in LC-MS-based metabolomics for clinical biomarker discovery. Mass Spectrom Rev, e21785. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35645144. https:\/\/doi.org\/10.1002\/mas.21785.","DOI":"10.1002\/mas.21785"},{"key":"2105_CR6","doi-asserted-by":"publisher","unstructured":"Contini, C., Serrao, S., Manconi, B., Olianas, A., Iavarone, F., Bizzarro, A., & Cabras, T. (2022). Salivary Proteomics Reveals Significant Changes in Relation to Alzheimer\u2019s Disease and Aging. J Alzheimers Dis. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35912740. https:\/\/doi.org\/10.3233\/JAD-220246.","DOI":"10.3233\/JAD-220246"},{"key":"2105_CR7","doi-asserted-by":"publisher","unstructured":"Cuevas-Cordoba, B., & Santiago-Garcia, J. (2014). Saliva: a fluid of study for OMICS. OMICS, 18(2), 87\u201397. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24404837. https:\/\/doi.org\/10.1089\/omi.2013.0064.","DOI":"10.1089\/omi.2013.0064"},{"key":"2105_CR8","doi-asserted-by":"publisher","unstructured":"Duarte, D., Castro, B., Pereira, J. L., Marques, J. F., Costa, A. L., & Gil, A. M. (2020). Evaluation of Saliva Stability for NMR Metabolomics: Collection and Handling Protocols. Metabolites, 10(12). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33352779. https:\/\/doi.org\/10.3390\/metabo10120515.","DOI":"10.3390\/metabo10120515"},{"key":"2105_CR9","doi-asserted-by":"publisher","unstructured":"Figueira, J., Gouveia-Figueira, S., Ohman, C., Lif Holgerson, P., Nording, M. L., & Ohman, A. (2017). Metabolite quantification by NMR and LC-MS\/MS reveals differences between unstimulated, stimulated, and pure parotid saliva. J Pharm Biomed Anal, 140, 295\u2013300. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28380387. https:\/\/doi.org\/10.1016\/j.jpba.2017.03.037.","DOI":"10.1016\/j.jpba.2017.03.037"},{"key":"2105_CR11","doi-asserted-by":"publisher","unstructured":"Gardner, A., Parkes, H. G., Carpenter, G. H., & So, P. W. (2018). Developing and Standardizing a Protocol for Quantitative Proton Nuclear Magnetic Resonance ((1)H NMR) Spectroscopy of Saliva. J Proteome Res, 17(4), 1521\u20131531. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29498859. https:\/\/doi.org\/10.1021\/acs.jproteome.7b00847.","DOI":"10.1021\/acs.jproteome.7b00847"},{"key":"2105_CR10","doi-asserted-by":"publisher","unstructured":"Gardner, A., Carpenter, G., & So, P. W. (2020). Salivary Metabolomics: From Diagnostic Biomarker Discovery to Investigating Biological Function. Metabolites, 10(2). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31991929. https:\/\/doi.org\/10.3390\/metabo10020047.","DOI":"10.3390\/metabo10020047"},{"key":"2105_CR12","doi-asserted-by":"publisher","unstructured":"Gevi, F., Meloni, A., Mereu, R., Lelli, V., Chiodo, A., Ragusa, A., & Timperio, A. M. (2020). Urine Metabolome during Parturition. Metabolites, 10(7). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32708819. https:\/\/doi.org\/10.3390\/metabo10070290.","DOI":"10.3390\/metabo10070290"},{"key":"2105_CR13","doi-asserted-by":"publisher","unstructured":"Hosseinkhani, F., Dubbelman, A. C., Karu, N., Harms, A. C., & Hankemeier, T. (2021). Towards Standards for Human Fecal Sample Preparation in Targeted and Untargeted LC-HRMS Studies. Metabolites, 11(6). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34200487. https:\/\/doi.org\/10.3390\/metabo11060364.","DOI":"10.3390\/metabo11060364"},{"key":"2105_CR35","doi-asserted-by":"publisher","unstructured":"https:\/\/mdpi-res.com\/d_attachment\/ijms\/ijms-22-13643\/article_deploy\/ijms-22-13643.pdf?version=1639993512. https:\/\/doi.org\/10.3390\/ijms222413643.","DOI":"10.3390\/ijms222413643"},{"key":"2105_CR14","doi-asserted-by":"publisher","unstructured":"Hyvarinen, E., Savolainen, M., Mikkonen, J. J. W., & Kullaa, A. M. (2021). Salivary Metabolomics for Diagnosis and Monitoring Diseases: Challenges and Possibilities. Metabolites, 11(9). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34564402. https:\/\/doi.org\/10.3390\/metabo11090587.","DOI":"10.3390\/metabo11090587"},{"key":"2105_CR15","doi-asserted-by":"publisher","unstructured":"Janeckova, H., Kalivodova, A., Najdekr, L., Friedecky, D., Hron, K., Bruheim, P., & Adam, T. (2015). Untargeted metabolomic analysis of urine samples in the diagnosis of some inherited metabolic disorders. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 159(4), 582\u2013585. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25482736. https:\/\/doi.org\/10.5507\/bp.2014.048.","DOI":"10.5507\/bp.2014.048"},{"key":"2105_CR16","doi-asserted-by":"publisher","unstructured":"Kawanishi, N., Hoshi, N., Masahiro, S., Enomoto, A., Ota, S., Kaneko, M., & Kimoto, K. (2019). Effects of inter-day and intra-day variation on salivary metabolomic profiles. Clin Chim Acta, 489, 41\u201348. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30481500. https:\/\/doi.org\/10.1016\/j.cca.2018.11.030.","DOI":"10.1016\/j.cca.2018.11.030"},{"key":"2105_CR17","unstructured":"Klupczynska, A., Derezinski, P., & Kokot, Z. J. (2015). Metabolomics in Medical Sciences\u2013Trends, Challenges and Perspectives. Acta Pol Pharm, 72(4), 629\u2013641. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26647618."},{"key":"2105_CR18","doi-asserted-by":"publisher","unstructured":"Kuboniwa, M., Sakanaka, A., Hashino, E., Bamba, T., Fukusaki, E., & Amano, A. (2016). Prediction of Periodontal Inflammation via Metabolic Profiling of Saliva. J Dent Res, 95(12), 1381\u20131386. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27470067. https:\/\/doi.org\/10.1177\/0022034516661142.","DOI":"10.1177\/0022034516661142"},{"key":"2105_CR19","doi-asserted-by":"publisher","unstructured":"Lajin, B., Schweighofer, N., Goessler, W., & Obermayer-Pietsch, B. (2021). The determination of the Paraxanthine\/Caffeine ratio as a metabolic biomarker for CYP1A2 activity in various human matrices by UHPLC-ESIMS\/MS. Talanta, 234, 122658. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34364467. https:\/\/doi.org\/10.1016\/j.talanta.2021.122658.","DOI":"10.1016\/j.talanta.2021.122658"},{"key":"2105_CR20","doi-asserted-by":"publisher","unstructured":"Lercher, A., Baazim, H., & Bergthaler, A. (2020). Systemic Immunometabolism: Challenges and Opportunities. Immunity, 53(3), 496\u2013509. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32937151. https:\/\/doi.org\/10.1016\/j.immuni.2020.08.012.","DOI":"10.1016\/j.immuni.2020.08.012"},{"key":"2105_CR21","doi-asserted-by":"publisher","unstructured":"Li, Z., Sarnat, J. A., Liu, K. H., Hood, R. B., Chang, C. J., Hu, X., & Liang, D. (2022). Evaluation of the Use of Saliva Metabolome as a Surrogate of Blood Metabolome in Assessing Internal Exposures to Traffic-Related Air Pollution. Environ Sci Technol, 56(10), 6525\u20136536. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35476389. https:\/\/doi.org\/10.1021\/acs.est.2c00064.","DOI":"10.1021\/acs.est.2c00064"},{"key":"2105_CR22","doi-asserted-by":"publisher","unstructured":"Liebsch, C., Pitchika, V., Pink, C., Samietz, S., Kastenmuller, G., Artati, A., & Pietzner, M. (2019). The Saliva Metabolome in Association to Oral Health Status. J Dent Res, 98(6), 642\u2013651. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31026179. https:\/\/doi.org\/10.1177\/0022034519842853.","DOI":"10.1177\/0022034519842853"},{"key":"2105_CR23","doi-asserted-by":"publisher","unstructured":"Loo, J. A., Yan, W., Ramachandran, P., & Wong, D. T. (2010). Comparative human salivary and plasma proteomes. J Dent Res, 89(10), 1016\u20131023. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20739693. https:\/\/doi.org\/10.1177\/0022034510380414.","DOI":"10.1177\/0022034510380414"},{"key":"2105_CR24","doi-asserted-by":"publisher","unstructured":"Martias, C., Baroukh, N., Mavel, S., Blasco, H., Lefevre, A., Roch, L., & Emond, P. (2021). Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms. Molecules, 26(14). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34299389. https:\/\/doi.org\/10.3390\/molecules26144111.","DOI":"10.3390\/molecules26144111"},{"key":"2105_CR25","doi-asserted-by":"publisher","unstructured":"Montsko, G., Tarjanyi, Z., Mezosi, E., & Kovacs, G. L. (2014). A validated method for measurement of serum total, serum free, and salivary cortisol, using high-performance liquid chromatography coupled with high-resolution ESI-TOF mass spectrometry. Anal Bioanal Chem, 406(9\u201310), 2333\u20132341. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24604321. https:\/\/doi.org\/10.1007\/s00216-014-7642-x.","DOI":"10.1007\/s00216-014-7642-x"},{"key":"2105_CR26","unstructured":"National Institute for Occupational Safety and Health (2019). NIOSH Pocket Guide to Chemical Hazards. Centers for Diseases Control and Prevention Retrieved from https:\/\/www.cdc.gov\/."},{"key":"2105_CR27","doi-asserted-by":"publisher","unstructured":"Okhina, A. A., Rogachev, A. D., Yarovaya, O. I., Khvostov, M. V., Tolstikova, T. G., Pokrovsky, A. G., & Salakhutdinov, N. F. (2020). Development and validation of an LC-MS\/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent. J Pharm Biomed Anal, 180, 113039. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31865208. https:\/\/doi.org\/10.1016\/j.jpba.2019.113039.","DOI":"10.1016\/j.jpba.2019.113039"},{"key":"2105_CR28","doi-asserted-by":"publisher","unstructured":"Petruczynik, A., Wroblewski, K., Wojtanowski, K., Mroczek, T., Juchnowicz, D., Karakula-Juchnowicz, H., & Tuzimski, T. (2020). Comparison of Various Chromatographic Systems for Identification of Vortioxetine in Bulk Drug Substance, Human Serum, Saliva, and Urine Samples by HPLC-DAD and LC-QTOF-MS. Molecules, 25(11). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32471141. https:\/\/doi.org\/10.3390\/molecules25112483.","DOI":"10.3390\/molecules25112483"},{"key":"2105_CR29","doi-asserted-by":"publisher","unstructured":"Pozzi, C., Levi, R., Braga, D., Carli, F., Darwich, A., Spadoni, I., & Rescigno, M. (2022). A \u2018Multiomic\u2019 Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019. Gastro Hep Adv, 1(2), 194\u2013209. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35174369. https:\/\/doi.org\/10.1016\/j.gastha.2021.12.006.","DOI":"10.1016\/j.gastha.2021.12.006"},{"key":"2105_CR30","doi-asserted-by":"publisher","unstructured":"Pundir, M., Papagerakis, S., De Rosa, M. C., Chronis, N., Kurabayashi, K., Abdulmawjood, S., & Papagerakis, P. (2022). Emerging biotechnologies for evaluating disruption of stress, sleep, and circadian rhythm mechanism using aptamer-based detection of salivary biomarkers. Biotechnol Adv, 59, 107961. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35427723. https:\/\/doi.org\/10.1016\/j.biotechadv.2022.107961.","DOI":"10.1016\/j.biotechadv.2022.107961"},{"key":"2105_CR31","doi-asserted-by":"publisher","unstructured":"Rehm, K., Hankele, A. K., Ulbrich, S. E., & Bigler, L. (2024). Quantification of glucocorticoid and progestogen metabolites in bovine plasma, skimmed milk and saliva by UHPLC-HR-MS with polarity switching. Anal Chim Acta, 1287, 342118. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38182350. https:\/\/doi.org\/10.1016\/j.aca.2023.342118.","DOI":"10.1016\/j.aca.2023.342118"},{"key":"2105_CR32","doi-asserted-by":"publisher","unstructured":"Reyes-Garces, N., Boyaci, E., Gomez-Rios, G. A., Olkowicz, M., Monnin, C., Bojko, B., & Pawliszyn, J. (2021). Assessment of solid phase microextraction as a sample preparation tool for untargeted analysis of brain tissue using liquid chromatography-mass spectrometry. J Chromatogr A, 1638, 461862. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33433374. https:\/\/doi.org\/10.1016\/j.chroma.2020.461862.","DOI":"10.1016\/j.chroma.2020.461862"},{"key":"2105_CR33","doi-asserted-by":"publisher","unstructured":"Roca, M., Alcoriza, M. I., Garcia-Canaveras, J. C., & Lahoz, A. (2021). Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial. Anal Chim Acta, 1147, 38\u201355. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33485584. https:\/\/doi.org\/10.1016\/j.aca.2020.12.025.","DOI":"10.1016\/j.aca.2020.12.025"},{"key":"2105_CR34","doi-asserted-by":"crossref","unstructured":"Saini, R. K., Prasad, P., Shang, X., & Keum, Y. S. (2021). Advances in Lipid Extraction Methods-A Review. Int J Mol Sci, 22(24). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34948437.","DOI":"10.3390\/ijms222413643"},{"key":"2105_CR36","doi-asserted-by":"publisher","unstructured":"Song, X., Yang, X., Narayanan, R., Shankar, V., Ethiraj, S., Wang, X., & Zare, R. N. (2020). Oral squamous cell carcinoma diagnosed from saliva metabolic profiling. Proc Natl Acad Sci U S A, 117(28), 16167\u201316173. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32601197. https:\/\/doi.org\/10.1073\/pnas.2001395117.","DOI":"10.1073\/pnas.2001395117"},{"key":"2105_CR37","doi-asserted-by":"publisher","unstructured":"Tsuchida, S., & Nakayama, T. (2022). Metabolomics Research in Periodontal Disease by Mass Spectrometry. Molecules, 27(9). Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35566216. https:\/\/doi.org\/10.3390\/molecules27092864.","DOI":"10.3390\/molecules27092864"},{"key":"2105_CR38","doi-asserted-by":"publisher","unstructured":"Wiesen, M. H., Farowski, F., Feldkotter, M., Hoppe, B., & Muller, C. (2012). Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device. J Chromatogr A, 1241, 52\u201359. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22552204. https:\/\/doi.org\/10.1016\/j.chroma.2012.04.008.","DOI":"10.1016\/j.chroma.2012.04.008"},{"key":"2105_CR39","doi-asserted-by":"publisher","unstructured":"Yamada, E., Takagi, R., Sudo, K., & Kato, S. (2015). Determination of abacavir, tenofovir, darunavir, and raltegravir in human plasma and saliva using liquid chromatography coupled with tandem mass spectrometry. J Pharm Biomed Anal, 114, 390\u2013397. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26112927. https:\/\/doi.org\/10.1016\/j.jpba.2015.06.005.","DOI":"10.1016\/j.jpba.2015.06.005"},{"key":"2105_CR40","doi-asserted-by":"publisher","unstructured":"Yan, P., Qin, C., Yan, Z., Chen, C., & Zhang, F. (2023). Can salivary lactate be used as an anaerobic biomarker? PeerJ, 11, e15274. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37151289. https:\/\/doi.org\/10.7717\/peerj.15274.","DOI":"10.7717\/peerj.15274"},{"key":"2105_CR41","doi-asserted-by":"publisher","unstructured":"Zheng, J., Dixon, R. A., & Li, L. (2012). Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment. Anal Chem, 84(24), 10802\u201310811. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23150892. https:\/\/doi.org\/10.1021\/ac3028307.","DOI":"10.1021\/ac3028307"}],"container-title":["Metabolomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11306-024-02105-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11306-024-02105-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11306-024-02105-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T14:07:49Z","timestamp":1713535669000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11306-024-02105-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,9]]},"references-count":41,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,4]]}},"alternative-id":["2105"],"URL":"https:\/\/doi.org\/10.1007\/s11306-024-02105-2","relation":{},"ISSN":["1573-3890"],"issn-type":[{"value":"1573-3890","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,9]]},"assertion":[{"value":"27 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"<b>Statement<\/b>: Informed consent was obtained from all subjects involved in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"38"}}