{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T08:34:52Z","timestamp":1774600492826,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T00:00:00Z","timestamp":1459296000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Imaging Biol"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1007\/s11307-016-0948-7","type":"journal-article","created":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T20:15:03Z","timestamp":1459368903000},"page":"741-747","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Longitudinal Changes in Glucose Metabolism of Denervated Muscle after Complete Peripheral Nerve Injury"],"prefix":"10.1007","volume":"18","author":[{"given":"Kyoungjune","family":"Pak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Jun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Jun","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hong","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwa Kyoung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Jang","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,3,30]]},"reference":[{"key":"948_CR1","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/00005768-199612000-00004","volume":"28","author":"A Eberstein","year":"1996","unstructured":"Eberstein A, Eberstein S (1996) Electrical stimulation of denervated muscle: is it worthwhile? Med Sci Sports Exerc 28:1463\u20131469","journal-title":"Med Sci Sports Exerc"},{"key":"948_CR2","volume-title":"Surgery of the peripheral nerve. Thieme Medical Publishers","author":"SE Mackinnon","year":"1988","unstructured":"Mackinnon SE, Dellon AL (1988) Surgery of the peripheral nerve. Thieme Medical Publishers, 1st edn","edition":"1"},{"key":"948_CR3","first-page":"414","volume":"23","author":"A Ropo","year":"1992","unstructured":"Ropo A (1992) Orbicular muscle akinesia: a comparison, using electromyography, of three techniques. Ophthalmic Surg 23:414\u2013417","journal-title":"Ophthalmic Surg"},{"key":"948_CR4","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1097\/00006123-199904000-00077","volume":"44","author":"GA Grant","year":"1999","unstructured":"Grant GA, Goodkin R, Kliot M (1999) Evaluation and surgical management of peripheral nerve problems. Neurosurgery 44:825\u2013839, discussion 839-840","journal-title":"Neurosurgery"},{"key":"948_CR5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s11420-005-0124-0","volume":"2","author":"J Feinberg","year":"2006","unstructured":"Feinberg J (2006) EMG: myths and facts. HSS J 2:19\u201321","journal-title":"HSS J"},{"key":"948_CR6","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00256-007-0409-0","volume":"37","author":"S Kamath","year":"2008","unstructured":"Kamath S, Venkatanarasimha N, Walsh MA, Hughes PM (2008) MRI appearance of muscle denervation. Skeletal Radiol 37:397\u2013404","journal-title":"Skeletal Radiol"},{"key":"948_CR7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.expneurol.2004.03.025","volume":"188","author":"M Bendszus","year":"2004","unstructured":"Bendszus M, Wessig C, Solymosi L, Reiners K, Koltzenburg M (2004) MRI of peripheral nerve degeneration and regeneration: correlation with electrophysiology and histology. Exp Neurol 188:171\u2013177","journal-title":"Exp Neurol"},{"key":"948_CR8","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/ncpneuro0017","volume":"1","author":"M Bendszus","year":"2005","unstructured":"Bendszus M, Stoll G (2005) Technology insight: visualizing peripheral nerve injury using MRI. Nat Clin Pract Neurol 1:45\u201353","journal-title":"Nat Clin Pract Neurol"},{"key":"948_CR9","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1517\/17530059.2012.692904","volume":"6","author":"LD Hobson-Webb","year":"2012","unstructured":"Hobson-Webb LD, Padua L, Martinoli C (2012) Ultrasonography in the diagnosis of peripheral nerve disease. Expert Opin Med Diagn 6:457\u2013471","journal-title":"Expert Opin Med Diagn"},{"key":"948_CR10","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.2967\/jnumed.110.084731","volume":"52","author":"D Behera","year":"2011","unstructured":"Behera D, Jacobs KE, Behera S, Rosenberg J, Biswal S (2011) (18)F-FDG PET\/MRI can be used to identify injured peripheral nerves in a model of neuropathic pain. J Nucl Med 52:1308\u20131312","journal-title":"J Nucl Med"},{"key":"948_CR11","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.2967\/jnumed.114.140731","volume":"55","author":"SH Lee","year":"2014","unstructured":"Lee SH, Oh BM, Lee G, Choi H, Cheon GJ, Lee SU (2014) Feasibility of 18F-FDG PET as a noninvasive diagnostic tool of muscle denervation: a preliminary study. J Nucl Med 55:1737\u20131740","journal-title":"J Nucl Med"},{"key":"948_CR12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00006231-199802000-00002","volume":"19","author":"TA Smith","year":"1998","unstructured":"Smith TA (1998) FDG uptake, tumour characteristics and response to therapy: a review. Nucl Med Commun 19:97\u2013105","journal-title":"Nucl Med Commun"},{"key":"948_CR13","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1172\/JCI115465","volume":"88","author":"NE Block","year":"1991","unstructured":"Block NE, Menick DR, Robinson KA, Buse MG (1991) Effect of denervation on the expression of two glucose transporter isoforms in rat hindlimb muscle. J Clin Invest 88:1546\u20131552","journal-title":"J Clin Invest"},{"key":"948_CR14","first-page":"E50","volume":"271","author":"A Handberg","year":"1996","unstructured":"Handberg A, Megeney LA, McCullagh KJ, Kayser L, Han XX, Bonen A (1996) Reciprocal GLUT-1 and GLUT-4 expression and glucose transport in denervated muscles. Am J Physiol 271:E50\u2013E57","journal-title":"Am J Physiol"},{"key":"948_CR15","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1210\/endo.131.4.1396328","volume":"131","author":"L Coderre","year":"1992","unstructured":"Coderre L, Monfar MM, Chen KS et al (1992) Alteration in the expression of GLUT-1 and GLUT-4 protein and messenger RNA levels in denervated rat muscles. Endocrinol 131:1821\u20131825","journal-title":"Endocrinol"},{"key":"948_CR16","first-page":"45","volume":"12","author":"D Quan","year":"1999","unstructured":"Quan D, Bird SJ (1999) Nerve conduction studies and electromyography in the evaluation of peripheral nerve injuries. Univ Pa Orthop J 12:45\u201351","journal-title":"Univ Pa Orthop J"},{"key":"948_CR17","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0733-8619(18)30188-9","volume":"10","author":"GJ Parry","year":"1992","unstructured":"Parry GJ (1992) Electrodiagnostic studies in the evaluation of peripheral nerve and brachial plexus injuries. Neurol Clin 10:921\u2013934","journal-title":"Neurol Clin"},{"key":"948_CR18","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/bbrc.1997.7241","volume":"238","author":"JP Jones","year":"1997","unstructured":"Jones JP, Roberts BR, Tapscott EB, Dohm GL (1997) Transcriptional regulation of hexokinase II in denervated rat skeletal muscle. Biochem Biophys Res Commun 238:53\u201355","journal-title":"Biochem Biophys Res Commun"},{"key":"948_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.62.1.1-34.1998","volume":"62","author":"SS Pao","year":"1998","unstructured":"Pao SS, Paulsen IT, Saier MH Jr (1998) Major facilitator superfamily. Microbiol Mol Biol Rev 62:1\u201334","journal-title":"Microbiol Mol Biol Rev"},{"key":"948_CR20","doi-asserted-by":"crossref","first-page":"E141","DOI":"10.1152\/ajpendo.00712.2009","volume":"298","author":"B Thorens","year":"2010","unstructured":"Thorens B, Mueckler M (2010) Glucose transporters in the 21st century. Am J Physiol Endocrinol Metab 298:E141\u2013E145","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"948_CR21","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1385\/ENDO:19:1:13","volume":"19","author":"MU Baumann","year":"2002","unstructured":"Baumann MU, Deborde S, Illsley NP (2002) Placental glucose transfer and fetal growth. Endocrine 19:13\u201322","journal-title":"Endocrine"},{"key":"948_CR22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1079\/BJN2002763","volume":"89","author":"IS Wood","year":"2003","unstructured":"Wood IS, Trayhurn P (2003) Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Brit J Nutr 89:3\u20139","journal-title":"Brit J Nutr"},{"key":"948_CR23","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.12359","author":"ZJ Callahan","year":"2015","unstructured":"Callahan ZJ, Oxendine M, Wheatley JL et al (2015) Compensatory responses of the insulin signaling pathway restore muscle glucose uptake following long-term denervation. Physiol Rep. doi: 10.14814\/phy2.12359","journal-title":"Physiol Rep"},{"key":"948_CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0012-1606(88)90183-2","volume":"127","author":"S Schiaffino","year":"1988","unstructured":"Schiaffino S, Gorza L, Pitton G et al (1988) Embryonic and neonatal myosin heavy chain in denervated and paralyzed rat skeletal muscle. Dev Biol 127:1\u201311","journal-title":"Dev Biol"},{"key":"948_CR25","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1073\/pnas.81.4.1122","volume":"81","author":"R Matsuda","year":"1984","unstructured":"Matsuda R, Spector D, Strohman RC (1984) Denervated skeletal muscle displays discoordinate regulation for the synthesis of several myofibrillar proteins. Proc Natl Acad Sci U S A 81:1122\u20131125","journal-title":"Proc Natl Acad Sci U S A"},{"key":"948_CR26","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0896-6273(88)90195-X","volume":"1","author":"Y Gu","year":"1988","unstructured":"Gu Y, Hall ZW (1988) Immunological evidence for a change in subunits of the acetylcholine receptor in developing and denervated rat muscle. Neuron 1:117\u2013125","journal-title":"Neuron"},{"key":"948_CR27","doi-asserted-by":"crossref","first-page":"7090","DOI":"10.1016\/S0021-9258(19)68926-X","volume":"256","author":"LJ Wardzala","year":"1981","unstructured":"Wardzala LJ, Jeanrenaud B (1981) Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. Apparent translocation of intracellular transport units to the plasma membrane. J Biol Chem 256:7090\u20137093","journal-title":"J Biol Chem"},{"key":"948_CR28","first-page":"R1148","volume":"269","author":"LA Megeney","year":"1995","unstructured":"Megeney LA, Michel RN, Boudreau CS et al (1995) Regulation of muscle glucose transport and GLUT-4 by nerve-derived factors and activity-related processes. Am J Physiol 269:R1148\u2013R1153","journal-title":"Am J Physiol"},{"key":"948_CR29","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/1742-2094-8-110","volume":"8","author":"AD Gaudet","year":"2011","unstructured":"Gaudet AD, Popovich PG, Ramer MS (2011) Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury. J Neuroinflammation 8:110","journal-title":"J Neuroinflammation"},{"key":"948_CR30","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1042\/bj1280789","volume":"128","author":"LV Turner","year":"1972","unstructured":"Turner LV, Manchester KL (1972) Effects of denervation on the glycogen content and on the activities of enzymes of glucose and glycogen metabolism in rat diaphragm muscle. Biochem J 128:789\u2013801","journal-title":"Biochem J"},{"key":"948_CR31","first-page":"488","volume":"41","author":"T Doenst","year":"2000","unstructured":"Doenst T, Taegtmeyer H (2000) Kinetic differences and similarities among 3 tracers of myocardial glucose uptake. J Nucl Med 41:488\u2013492","journal-title":"J Nucl Med"}],"container-title":["Molecular Imaging and Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11307-016-0948-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11307-016-0948-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11307-016-0948-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T17:38:20Z","timestamp":1655401100000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11307-016-0948-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,30]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["948"],"URL":"https:\/\/doi.org\/10.1007\/s11307-016-0948-7","relation":{},"ISSN":["1536-1632","1860-2002"],"issn-type":[{"value":"1536-1632","type":"print"},{"value":"1860-2002","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,30]]}}}