{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:45:44Z","timestamp":1791499544773,"version":"4.3.4"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,11,26]],"date-time":"2013-11-26T00:00:00Z","timestamp":1385424000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1007\/s11325-013-0915-3","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T01:40:20Z","timestamp":1385343620000},"page":"533-539","source":"Crossref","is-referenced-by-count":54,"title":["Adenotonsillectomy and orthodontic therapy in pediatric obstructive sleep apnea"],"prefix":"10.1007","volume":"18","author":[{"given":"Maria Pia","family":"Villa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Castaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Miano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Chiara","family":"Paolino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavio","family":"Vitelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Tabarrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Rita","family":"Mazzotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Cecili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Barreto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,11,26]]},"reference":[{"key":"915_CR1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1542\/peds.102.3.616","volume":"102","author":"D Gozal","year":"1998","unstructured":"Gozal D (1998) Sleep-disordered breathing and school performance in children. Pediatrics 102:616\u2013620","journal-title":"Pediatrics"},{"key":"915_CR2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/sleep\/25.1.59","volume":"25","author":"D Gozal","year":"2002","unstructured":"Gozal D, Lipton AJ, Jones KL (2002) Circulating vascular endothelial growth factor levels in patients with obstructive sleep apnea. Sleep 25:59\u201365","journal-title":"Sleep"},{"key":"915_CR3","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1161\/CIRCULATIONAHA.107.696823","volume":"116","author":"D Gozal","year":"2007","unstructured":"Gozal D, Kheirandish-Gozal L, Serpero LD, Sans Capdevila O, Dayyat E (2007) Obstructive sleep apnea and endothelial function in school-aged non obese children: effect of adenotonsillectomy. Circulation 116:2307\u20132314","journal-title":"Circulation"},{"key":"915_CR4","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/HYPERTENSIONAHA.107.099762","volume":"51","author":"R Amin","year":"2008","unstructured":"Amin R, Somers VK, McConnell K, Willging P, Myer C, Sherman M, McPhail G, Morgenthal A, Fenchel M, Bean J, Kimball T, Daniels S (2008) Activity-adjusted 24-hour ambulatory blood pressure and cardiac remodeling in children with sleep disordered breathing. Hypertension 51:84\u201391","journal-title":"Hypertension"},{"key":"915_CR5","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1152\/jappl.1994.77.2.918","volume":"77","author":"CL Marcus","year":"1994","unstructured":"Marcus CL, McColley SA, Carroll JL, Loughlin GM, Smith PL, Schwartz AR (1994) Upper airway collapsibility in children with obstructive sleep apnea syndrome. J Appl Physiol 77:918\u2013924","journal-title":"J Appl Physiol"},{"key":"915_CR6","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1093\/sleep\/27.5.997","volume":"27","author":"R Arens","year":"2004","unstructured":"Arens R, Marcus CL (2004) Pathophysiology of upper airway obstruction: a developmental perspective. Sleep 27:997\u20131019","journal-title":"Sleep"},{"key":"915_CR7","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.5665\/sleep.1388","volume":"34","author":"S Redline","year":"2011","unstructured":"Redline S, Amin R, Beebe D, Chervin RD, Garetz SL, Giordani B, Marcus CL, Moore RH, Rosen CL, Arens R, Gozal D, Katz ES, Mitchell RB, Muzumdar H, Taylor HG, Thomas N, Ellenberg S (2011) The Childhood Adenotonsillectomy Trial (CHAT): rationale, design, and challenges of a randomized controlled trial evaluating a standard surgical procedure in a pediatric population. Sleep 34:1509\u20131517","journal-title":"Sleep"},{"key":"915_CR8","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1001\/2013.jamaoto.197","volume":"138","author":"DK Chan","year":"2012","unstructured":"Chan DK, Jan TA, Koltai PJ (2012) Effect of obesity and medical comorbidities on outcomes after adjunct surgery for obstructive sleep apnea in cases of adenotonsillectomy failure. Arch Otolaryngol Head Neck Surg 138:891\u2013896","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"915_CR9","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.otohns.2006.02.033","volume":"134","author":"SE Brietzke","year":"2006","unstructured":"Brietzke SE, Gallagher D (2006) The effectiveness of tonsillectomy and adenoidectomy in the treatment of pediatric obstructive sleep apnea\/hypopnea syndrome: a meta-analysis. Otolaryngol Head Neck Surg 134:979\u2013984","journal-title":"Otolaryngol Head Neck Surg"},{"key":"915_CR10","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1183\/09031936.05.00082904","volume":"25","author":"HE Montgomery-Downs","year":"2005","unstructured":"Montgomery-Downs HE, Crabtree VM, Gozal D (2005) Cognition, sleep and respiration in at risk children treated for obstructive sleep apnoea. Eur Respir J 25:336\u2013342","journal-title":"Eur Respir J"},{"key":"915_CR11","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1001\/archotol.131.4.308","volume":"131","author":"MG Stewart","year":"2005","unstructured":"Stewart MG, Glaze DG, Friedman EM, Smith EO, Bautista M (2005) Quality of life and sleep study findings after adenotonsillectomy in children with obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 131:308\u2013314","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"915_CR12","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1001\/archotol.130.2.190","volume":"130","author":"RB Mitchell","year":"2004","unstructured":"Mitchell RB, Kelly J, Call E et al (2004) Quality of life after adenotonsillectomy for obstructive sleep apnea in children. Arch Otolaryngol Head Neck Surg 130:190\u2013194","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"915_CR13","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1001\/archotol.130.4.409","volume":"130","author":"RB Mitchell","year":"2004","unstructured":"Mitchell RB, Kelly J, Call E, Yao N (2004) Long-term changes in quality of life after surgery for pediatric obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 130:409\u2013412","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"915_CR14","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1001\/archotol.131.1.52","volume":"131","author":"KD Tran","year":"2005","unstructured":"Tran KD, Nguyen CD, Weedon J, Goldestein NA (2005) Child behavior and quality of life in pediatric obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 131:52\u201357","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"915_CR15","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1097\/00005537-200310000-00003","volume":"113","author":"VA Flanary","year":"2003","unstructured":"Flanary VA (2003) Long-term effect of adenotonsillectomy on quality of life in pediatric patients. Laryngoscope 113:1639\u20131644","journal-title":"Laryngoscope"},{"key":"915_CR16","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.jpeds.2006.08.067","volume":"149","author":"R Tauman","year":"2006","unstructured":"Tauman R, Gulliver TE, Krishna J et al (2006) Persistence of obstructive sleep apnea syndrome in children after adenotonsillectomy. J Pediatr 149:803\u2013808","journal-title":"J Pediatr"},{"key":"915_CR17","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1164\/rccm.200912-1930OC","volume":"182","author":"R Bhattacharjee","year":"2010","unstructured":"Bhattacharjee R, Kheirandish-Gozal L, Spruyt K, Mitchell RB, Promchiarak J, Simakajornboon N, Kaditis AG, Splaingard D, Splaingard M, Brooks LJ, Marcus CL, Sin S, Arens R, Verhulst SL, Gozal D (2010) Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study. Am J Respir Crit Care Med 182:676\u2013683","journal-title":"Am J Respir Crit Care Med"},{"key":"915_CR18","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1056\/NEJMoa1215881","volume":"368","author":"CL Marcus","year":"2013","unstructured":"Marcus CL, Moore RH, Rosen CL, Giordani B, Garetz SL, Taylor HG, Mitchell RB, Amin R, Katz ES, Arens R, Paruthi S, Muzumdar H, Gozal D, Thomas NH, Ware J, Beebe D, Snyder K, Elden L, Sprecher RC, Willging P, Jones D, Bent JP, Hoban T, Chervin RD, Ellenberg SS, Redline S, for the Childhood Adenotonsillectomy Trial (CHAT) (2013) A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med 368:2366\u20132376","journal-title":"N Engl J Med."},{"key":"915_CR19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.mcna.2010.02.004","volume":"94","author":"P Pirelli","year":"2010","unstructured":"Pirelli P, Saponara M, De Rosa C, Fanucci E (2010) Orthodontics and obstructive sleep apnea in children. Med Clin North Am 94:517\u2013529","journal-title":"Med Clin North Am"},{"key":"915_CR20","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.otohns.2006.09.021","volume":"136","author":"C Guilleminault","year":"2007","unstructured":"Guilleminault C, Huang YS, Glamann C, Li K, Chan A (2007) Adenotonsillectomy and obstructive sleep apnea in children: a prospective survey. Otolaryngol Head Neck Surg 136:169\u2013175","journal-title":"Otolaryngol Head Neck Surg"},{"key":"915_CR21","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s11325-011-0505-1","volume":"5","author":"MP Villa","year":"2011","unstructured":"Villa MP, Miano S, Rizzoli A (2011) Mandibular advancement devices are an alternative and valid treatment for pediatric obstructive sleep apnea syndrome. Sleep Breath 5:179\u2013184","journal-title":"Sleep Breath"},{"key":"915_CR22","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s11325-010-0419-3","volume":"15","author":"C Guilleminault","year":"2011","unstructured":"Guilleminault C, Monteyrol PJ, Huynh NT, Pirelli P, Quo S, Li K (2011) Adeno-tonsillectomy and rapid maxillary distraction in pre-pubertal children, a pilot study. Sleep Breath 15:173\u2013177","journal-title":"Sleep Breath"},{"key":"915_CR23","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.sleep.2006.06.009","volume":"8","author":"MP Villa","year":"2007","unstructured":"Villa MP, Malagola C, Pagani J, Montesano M, Rizzoli A, Guilleminault C, Ronchetti R (2007) Rapid maxillary expansion in children with obstructive sleep apnea syndrome: 12-month follow-up. Sleep Med 8:128\u2013134","journal-title":"Sleep Med"},{"key":"915_CR24","volume-title":"The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications","author":"Iber C, Ancoli-Israel S, Chesson A, Quan SF, for the American Academy of Sleep Medicine","year":"2007","unstructured":"Iber C, Ancoli-Israel S, Chesson A, Quan SF, for the American Academy of Sleep Medicine (2007) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications, 1st edn. American Academy of Sleep Medicine, Westchester, IL","edition":"1"},{"key":"915_CR25","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1136\/bmj.320.7244.1240","volume":"6","author":"TJ Cole","year":"2000","unstructured":"Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 6:1240\u20131243","journal-title":"BMJ"},{"key":"915_CR26","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/00005537-200403000-00013","volume":"114","author":"M Friedman","year":"2004","unstructured":"Friedman M, Ibrahim H, Joseph NJ (2004) Staging of obstructive sleep apnea\/hypopnea syndrome: a guide to appropriate treatment. Laringoscope 114:454\u2013459","journal-title":"Laringoscope"},{"key":"915_CR27","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S0022-3476(94)70007-9","volume":"125","author":"CL Marcus","year":"1994","unstructured":"Marcus CL, Carroll JL, Koerner CB, Hamer A, Lutz J, Loughlin GM (1994) Determinants of growth in children with the obstructive sleep apnea syndrome. J Pediatr 125:556\u2013562","journal-title":"J Pediatr"},{"key":"915_CR28","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1002\/lary.23590","volume":"122","author":"PW Cheng","year":"2012","unstructured":"Cheng PW, Fang KM, Su HW, Huang TW (2012) Improved objective outcomes and quality of life after adenotonsillectomy with inferior turbinate reduction in pediatric obstructive sleep apnea with inferior turbinate hypertrophy. Laryngoscope 122:2850\u20132854","journal-title":"Laryngoscope"},{"key":"915_CR29","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/0194599810392328","volume":"144","author":"A Jeyakumar","year":"2011","unstructured":"Jeyakumar A, Fettman N, Armbrecht ES, Mitchell R (2011) A systematic review of adenotonsillectomy as a risk factor for childhood obesity. Otolaryngol Head Neck Surg 144:154\u2013158","journal-title":"Otolaryngol Head Neck Surg"},{"key":"915_CR30","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1542\/peds.2005-1007","volume":"17","author":"JN Roemmich","year":"2006","unstructured":"Roemmich JN, Barkley JE, D\u2019Andrea L, Nikova M, Rogol AD, Carskadon MA, Suratt PM (2006) Increases in overweight after adenotonsillectomy in overweight children with obstructive sleep-disordered breathing are associated with decreases in motor activity and hyperactivity. Pediatrics 17:200\u2013208","journal-title":"Pediatrics"},{"key":"915_CR31","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1542\/peds.109.4.e55","volume":"109","author":"P Nieminen","year":"2002","unstructured":"Nieminen P, L\u00f6pp\u00f6nen T, Tolonen U, Lanning P, Knip M, L\u00f6pp\u00f6nen H (2002) Growth and biochemical markers of growth in children with snoring and obstructive sleep apnea. Pediatrics 109:e55","journal-title":"Pediatrics"},{"key":"915_CR32","first-page":"542","volume-title":"Sleep disordered breathing in children: a comprehensive clinical guide to evaluation and treatment","author":"MP Villa","year":"2012","unstructured":"Villa MP, Miano S (2012) Mandibular advancement devices. In: Kheirandish-Gozal L, Gozal D (eds) Sleep disordered breathing in children: a comprehensive clinical guide to evaluation and treatment. Heidelberg: Humana Press, New York, pp 542\u2013551"},{"key":"915_CR33","first-page":"229","volume":"27","author":"MP Villa","year":"2001","unstructured":"Villa MP, Bertarini A, Pagani J, Paggi B, Montesano M, Alterio A, Cerone E, Masieri S, Ronchetti R (2001) Terapia miofunzionale in bambini con ostruzione delle alte vie respiratorie. RIP 27:229\u2013236","journal-title":"RIP"},{"key":"915_CR34","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1164\/rccm.200806-981OC","volume":"179","author":"KC Guimar\u00e3es","year":"2009","unstructured":"Guimar\u00e3es KC, Drager LF, Genta PR, Marcondes BF, Lorenzi-Filho G (2009) Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome. Am J Respir Crit Care Med 179:962\u2013966","journal-title":"Am J Respir Crit Care Med"},{"key":"915_CR35","doi-asserted-by":"crossref","unstructured":"Guilleminault C, Huang YS, Monteyrol PJ, Sato R, Quo S, Lin CH. Critical role of myofascial reeducation in pediatric sleep-disordered breathing. Sleep Med 14:518\u2013525","DOI":"10.1016\/j.sleep.2013.01.013"},{"key":"915_CR36","first-page":"184","volume":"3","author":"YS Huang","year":"2012","unstructured":"Huang YS, Guilleminault C (2012) Pediatric obstructive sleep apnea and the critical role of oral\u2013facial growth: evidences. Front Neurol 3:184","journal-title":"Front Neurol"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-013-0915-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11325-013-0915-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-013-0915-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,3]],"date-time":"2019-08-03T21:25:49Z","timestamp":1564867549000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11325-013-0915-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,26]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["915"],"URL":"https:\/\/doi.org\/10.1007\/s11325-013-0915-3","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,26]]}}}