{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T22:37:21Z","timestamp":1769207841161,"version":"3.49.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T00:00:00Z","timestamp":1486425600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education","award":["2014-R1A2A1A11052103 to HWL"],"award-info":[{"award-number":["2014-R1A2A1A11052103 to HWL"]}]},{"name":"Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education","award":["2015R1D1A1A01057934"],"award-info":[{"award-number":["2015R1D1A1A01057934"]}]},{"name":"Ministry of Health and Family Welfare (Korea)","award":["HI14C1989"],"award-info":[{"award-number":["HI14C1989"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1007\/s11325-016-1450-9","type":"journal-article","created":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T23:38:48Z","timestamp":1486424328000},"page":"639-646","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Is obstructive sleep apnea associated with the presence of intracranial cerebral atherosclerosis?"],"prefix":"10.1007","volume":"21","author":[{"given":"Tae-Jin","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Hyun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju-Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunseo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoonkyung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeon Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jangsup","family":"Moon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Jae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyang Woon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,2,7]]},"reference":[{"issue":"1","key":"1450_CR1","doi-asserted-by":"publisher","first-page":"27","DOI":"10.5853\/jos.2014.16.1.27","volume":"16","author":"OY Bang","year":"2014","unstructured":"Bang OY (2014) Intracranial atherosclerosis: current understanding and perspectives. J Stroke 16(1):27\u201335. doi: 10.5853\/jos.2014.16.1.27","journal-title":"J Stroke"},{"issue":"1","key":"1450_CR2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1212\/01.WNL.0000132637.30287.B4","volume":"63","author":"JF Arenillas","year":"2004","unstructured":"Arenillas JF, Molina CA, Chacon P, Rovira A, Montaner J, Coscojuela P, Sanchez E, Quintana M, Alvarez-Sabin J (2004) High lipoprotein (a), diabetes, and the extent of symptomatic intracranial atherosclerosis. Neurology 63(1):27\u201332","journal-title":"Neurology"},{"issue":"1","key":"1450_CR3","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3988\/jcn.2006.2.1.29","volume":"2","author":"KY Park","year":"2006","unstructured":"Park KY, Chung CS, Lee KH, Kim GM, Kim YB, Oh K (2006) Prevalence and risk factors of intracranial atherosclerosis in an asymptomatic Korean population. J Clin Neurol 2(1):29\u201333. doi: 10.3988\/jcn.2006.2.1.29","journal-title":"J Clin Neurol"},{"issue":"19","key":"1450_CR4","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1056\/NEJMoa043104","volume":"353","author":"HK Yaggi","year":"2005","unstructured":"Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V (2005) Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 353(19):2034\u20132041. doi: 10.1056\/NEJMoa043104","journal-title":"N Engl J Med"},{"key":"1450_CR5","doi-asserted-by":"publisher","unstructured":"Song TJ, Park JH, Chang Y, Moon J, Kim JH, Heo JH, Kim YJ, Lee HW (2017) Moderate-to-severe obstructive sleep apnea is associated with cerebral small vessel disease. Sleep Med 30(2):36\u201342. http:\/\/dx.doi.org\/10.1016\/j.sleep.2016.03.006","DOI":"10.1016\/j.sleep.2016.03.006"},{"issue":"12","key":"1450_CR6","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/jhh.2015.15","volume":"29","author":"C Gonzaga","year":"2015","unstructured":"Gonzaga C, Bertolami A, Bertolami M, Amodeo C, Calhoun D (2015) Obstructive sleep apnea, hypertension and cardiovascular diseases. J Hum Hypertens 29(12):705\u2013712. doi: 10.1038\/jhh.2015.15","journal-title":"J Hum Hypertens"},{"issue":"5","key":"1450_CR7","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.smrv.2014.01.004","volume":"18","author":"SS Ali","year":"2014","unstructured":"Ali SS, Oni ET, Warraich HJ, Blaha MJ, Blumenthal RS, Karim A, Shaharyar S, Jamal O, Fialkow J, Cury R, Budoff MJ, Agatston AS, Nasir K (2014) Systematic review on noninvasive assessment of subclinical cardiovascular disease in obstructive sleep apnea: new kid on the block! Sleep Med Rev 18(5):379\u2013391. doi: 10.1016\/j.smrv.2014.01.004","journal-title":"Sleep Med Rev"},{"issue":"1","key":"1450_CR8","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1159\/000103611","volume":"24","author":"R Dziewas","year":"2007","unstructured":"Dziewas R, Ritter M, Usta N, Boentert M, Hor H, Dittrich R, Schabitz WR, Ringelstein EB, Young P (2007) Atherosclerosis and obstructive sleep apnea in patients with ischemic stroke. Cerebrovasc Dis 24(1):122\u2013126. doi: 10.1159\/000103611","journal-title":"Cerebrovasc Dis"},{"issue":"8","key":"1450_CR9","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1136\/jnnp.2004.054403","volume":"76","author":"OY Bang","year":"2005","unstructured":"Bang OY, Lee PH, Yoon SR, Lee MA, Joo IS, Huh K (2005) Inflammatory markers, rather than conventional risk factors, are different between carotid and MCA atherosclerosis. J Neurol Neurosurg Psychiatry 76(8):1128\u20131134. doi: 10.1136\/jnnp.2004.054403","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"1450_CR10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.5664\/jcsm.27497","volume":"5","author":"LJ Epstein","year":"2009","unstructured":"Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD, Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep M (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5(3):263\u2013276","journal-title":"J Clin Sleep Med"},{"issue":"7","key":"1450_CR11","doi-asserted-by":"crossref","first-page":"485","DOI":"10.7326\/0003-4819-131-7-199910050-00002","volume":"131","author":"NC Netzer","year":"1999","unstructured":"Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP (1999) Using the Berlin questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med 131(7):485\u2013491","journal-title":"Ann Intern Med"},{"issue":"4","key":"1450_CR12","first-page":"643","volume":"21","author":"OB Samuels","year":"2000","unstructured":"Samuels OB, Joseph GJ, Lynn MJ, Smith HA, Chimowitz MI (2000) A standardized method for measuring intracranial arterial stenosis. AJNR Am J Neuroradiol 21(4):643\u2013646","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"1450_CR13","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.atherosclerosis.2011.09.013","volume":"219","author":"J Kim","year":"2011","unstructured":"Kim J, Cha MJ, Lee DH, Lee HS, Nam CM, Nam HS, Kim YD, Heo JH (2011) The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke. Atherosclerosis 219(2):887\u2013891. doi: 10.1016\/j.atherosclerosis.2011.09.013","journal-title":"Atherosclerosis"},{"issue":"7","key":"1450_CR14","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1056\/NEJM199108153250701","volume":"325","author":"North American Symptomatic Carotid Endarterectomy Trial C","year":"1991","unstructured":"North American Symptomatic Carotid Endarterectomy Trial C (1991) Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325(7):445\u2013453. doi: 10.1056\/NEJM199108153250701","journal-title":"N Engl J Med"},{"issue":"5","key":"1450_CR15","doi-asserted-by":"publisher","first-page":"597","DOI":"10.5664\/jcsm.2172","volume":"8","author":"RB Berry","year":"2012","unstructured":"Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM, American Academy of Sleep M (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American Academy of Sleep Medicine. J Clin Sleep Med 8(5):597\u2013619. doi: 10.5664\/jcsm.2172","journal-title":"J Clin Sleep Med"},{"issue":"5","key":"1450_CR16","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1378\/chest.14-0970","volume":"146","author":"MJ Sateia","year":"2014","unstructured":"Sateia MJ (2014) International classification of sleep disorders-third edition: highlights and modifications. Chest 146(5):1387\u20131394. doi: 10.1378\/chest.14-0970","journal-title":"Chest"},{"issue":"3","key":"1450_CR17","doi-asserted-by":"publisher","first-page":"222","DOI":"10.3988\/jcn.2014.10.3.222","volume":"10","author":"TJ Song","year":"2014","unstructured":"Song TJ, Kim J, Lee HS, Nam CM, Nam HS, Kim YD, Heo JH (2014) Distribution of cerebral microbleeds determines their association with impaired kidney function. J Clin Neurol 10(3):222\u2013228. doi: 10.3988\/jcn.2014.10.3.222","journal-title":"J Clin Neurol"},{"issue":"9","key":"1450_CR18","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/s00392-015-0834-3","volume":"104","author":"CA Schaefer","year":"2015","unstructured":"Schaefer CA, Adam L, Weisser-Thomas J, Pingel S, Vogel G, Klarmann-Schulz U, Nickenig G, Pizarro C, Skowasch D (2015) High prevalence of peripheral arterial disease in patients with obstructive sleep apnoea. Clin Res Cardiol 104(9):719\u2013726. doi: 10.1007\/s00392-015-0834-3","journal-title":"Clin Res Cardiol"},{"issue":"10","key":"1450_CR19","doi-asserted-by":"publisher","first-page":"2338","DOI":"10.1161\/ATVBAHA.114.303965","volume":"34","author":"SI Gunnarsson","year":"2014","unstructured":"Gunnarsson SI, Peppard PE, Korcarz CE, Barnet JH, Aeschlimann SE, Hagen EW, Young T, Hla KM, Stein JH (2014) Obstructive sleep apnea is associated with future subclinical carotid artery disease: thirteen-year follow-up from the Wisconsin sleep cohort. Arterioscler Thromb Vasc Biol 34(10):2338\u20132342. doi: 10.1161\/ATVBAHA.114.303965","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"1450_CR20","doi-asserted-by":"publisher","first-page":"e001241","DOI":"10.1161\/JAHA.114.001241","volume":"3","author":"Y Kwon","year":"2014","unstructured":"Kwon Y, Duprez DA, Jacobs DR, Nagayoshi M, McClelland RL, Shahar E, Budoff M, Redline S, Shea S, Carr JJ, Lutsey PL (2014) Obstructive sleep apnea and progression of coronary artery calcium: the multi-ethnic study of atherosclerosis study. J Am Heart Assoc 3(5):e001241. doi: 10.1161\/JAHA.114.001241","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"1450_CR21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1046\/j.1365-2796.2001.00787.x","volume":"249","author":"A Elmasry","year":"2001","unstructured":"Elmasry A, Lindberg E, Berne C, Janson C, Gislason T, Awad Tageldin M, Boman G (2001) Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study. J Intern Med 249(2):153\u2013161","journal-title":"J Intern Med"},{"issue":"3","key":"1450_CR22","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1164\/rccm.200306-767OC","volume":"169","author":"MS Ip","year":"2004","unstructured":"Ip MS, Tse HF, Lam B, Tsang KW, Lam WK (2004) Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med 169(3):348\u2013353. doi: 10.1164\/rccm.200306-767OC","journal-title":"Am J Respir Crit Care Med"},{"key":"1450_CR23","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.atherosclerosis.2015.12.040","volume":"246","author":"OY Bang","year":"2016","unstructured":"Bang OY, Chung JW, Ryoo S, Moon GJ, Kim GM, Chung CS, Lee KH (2016) Brain microangiopathy and macroangiopathy share common risk factors and biomarkers. Atherosclerosis 246:71\u201377. doi: 10.1016\/j.atherosclerosis.2015.12.040","journal-title":"Atherosclerosis"},{"issue":"2","key":"1450_CR24","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0021-9290(80)90191-8","volume":"13","author":"K Hayashi","year":"1980","unstructured":"Hayashi K, Handa H, Nagasawa S, Okumura A, Moritake K (1980) Stiffness and elastic behavior of human intracranial and extracranial arteries. J Biomech 13(2):175\u2013184","journal-title":"J Biomech"},{"issue":"4","key":"1450_CR25","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1161\/01.STR.11.4.329","volume":"11","author":"FT Merei","year":"1980","unstructured":"Merei FT, Gallyas F, Horvath Z (1980) Elastic elements in the media and adventitia of human intracranial extracerebral arteries. Stroke 11(4):329\u2013336","journal-title":"Stroke"},{"issue":"5","key":"1450_CR26","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1164\/rccm.200412-1652OC","volume":"172","author":"K Minoguchi","year":"2005","unstructured":"Minoguchi K, Yokoe T, Tazaki T, Minoguchi H, Tanaka A, Oda N, Okada S, Ohta S, Naito H, Adachi M (2005) Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea. Am J Respir Crit Care Med 172(5):625\u2013630. doi: 10.1164\/rccm.200412-1652OC","journal-title":"Am J Respir Crit Care Med"},{"issue":"2\u20133","key":"1450_CR27","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1159\/000105681","volume":"24","author":"B Ovbiagele","year":"2007","unstructured":"Ovbiagele B, Lynn MJ, Saver JL, Chimowitz MI, Group WS (2007) Leukocyte count and vascular risk in symptomatic intracranial atherosclerosis. Cerebrovasc Dis 24(2\u20133):283\u2013288. doi: 10.1159\/000105681","journal-title":"Cerebrovasc Dis"},{"key":"1450_CR28","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.smrv.2014.07.003","volume":"20","author":"L Lavie","year":"2015","unstructured":"Lavie L (2015) Oxidative stress in obstructive sleep apnea and intermittent hypoxia\u2014revisited\u2014the bad ugly and good: implications to the heart and brain. Sleep Med Rev 20:27\u201345. doi: 10.1016\/j.smrv.2014.07.003","journal-title":"Sleep Med Rev"},{"issue":"1","key":"1450_CR29","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1152\/physrev.00018.2001","volume":"82","author":"W Droge","year":"2002","unstructured":"Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82(1):47\u201395. doi: 10.1152\/physrev.00018.2001","journal-title":"Physiol Rev"},{"issue":"5","key":"1450_CR30","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/sleep\/32.5.589","volume":"32","author":"AS Walters","year":"2009","unstructured":"Walters AS, Rye DB (2009) Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke. Sleep 32(5):589\u2013597","journal-title":"Sleep"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11325-016-1450-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-016-1450-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-016-1450-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T23:26:33Z","timestamp":1601594793000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11325-016-1450-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,7]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["1450"],"URL":"https:\/\/doi.org\/10.1007\/s11325-016-1450-9","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,7]]}}}