{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:37:36Z","timestamp":1770741456927,"version":"3.49.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T00:00:00Z","timestamp":1532390400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s11325-018-1699-2","type":"journal-article","created":{"date-parts":[[2018,7,25]],"date-time":"2018-07-25T00:47:54Z","timestamp":1532479674000},"page":"433-438","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reliability of autonomic activations as surrogates of cortical arousals in ventilated patients affected by amyotrophic lateral sclerosis"],"prefix":"10.1007","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-9544","authenticated-orcid":false,"given":"Grazia","family":"Crescimanno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Greco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Arrisicato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oreste","family":"Marrone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,7,24]]},"reference":[{"key":"1699_CR1","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s40675-017-0094-z","volume":"3","author":"LS Aboussouan","year":"2017","unstructured":"Aboussouan LS, Mireles-Cabodevila E (2017) Sleep in amyotrophic lateral sclerosis. Curr Sleep Medicine Rep 3:279\u2013289","journal-title":"Curr Sleep Medicine Rep"},{"key":"1699_CR2","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1016\/j.sleep.2014.06.010","volume":"15","author":"G Crescimanno","year":"2014","unstructured":"Crescimanno G, Misuraca A, Purrazzella G, Greco F, Marrone O (2014) Subjective sleep quality in stable neuromuscular patients under non-invasive ventilation. Sleep Med 15:1259\u20131263","journal-title":"Sleep Med"},{"key":"1699_CR3","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1080\/17843286.2016.1173941","volume":"71","author":"E Vandoorne","year":"2016","unstructured":"Vandoorne E, Vrijsen B, Belge C, Testelmans D, Buyse B (2016) Noninvasive ventilation in amyotrophic lateral sclerosis: effects on sleep quality and quality of life. Acta Clin Belg 71:389\u2013394","journal-title":"Acta Clin Belg"},{"key":"1699_CR4","doi-asserted-by":"publisher","unstructured":"Schellhas V, Glatz C, Beecken I, Okegwo A, Heidbreder A, Young P, Boentert M (2018) Upper airway obstruction induced by non-invasive ventilation using an oronasal interface. Sleep Breath. https:\/\/doi.org\/10.1007\/s11325-018-1640-8","DOI":"10.1007\/s11325-018-1640-8"},{"key":"1699_CR5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.5664\/jcsm.27941","volume":"6","author":"RB Berry","year":"2010","unstructured":"Berry RB, Chediak A, Brown LK, Finder J, Gozal D, Iber C, Kushida CA, Morgenthaler T, Rowley JA, Davidson-Ward SL (2010) NPPV titration task force of the American Academy of sleep medicine. Best clinical practices for the sleep center adjustment of noninvasive positive pressure ventilation (NPPV) in stable chronic alveolar hypoventilation syndromes. J Clin Sleep Med 6:491\u2013509","journal-title":"J Clin Sleep Med"},{"key":"1699_CR6","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1136\/jnnp-2015-312185","volume":"87","author":"T Prell","year":"2016","unstructured":"Prell T, Ringer TM, Wullenkord K, Garrison P, Gunkel A, Stubendorff B, Witte OW, Grosskreutz J (2016) Assessment of pulmonary function in amyotrophic lateral sclerosis: when can polygraphy help evaluate the need for non-invasive ventilation? J Neurol Neurosurg Psychiatry 87:1022\u201310267","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1699_CR7","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1042\/cs0870269","volume":"87","author":"D Pitson","year":"1994","unstructured":"Pitson D, Chhina N, Knijn S, van Herwaaden M, Stradling J (1994) Changes in pulse transit time and pulse rate as markers of arousal from sleep in normal subjects. Clin Sci 87:269\u2013273","journal-title":"Clin Sci"},{"key":"1699_CR8","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1093\/sleep\/33.12.1687","volume":"33","author":"A Delessert","year":"2010","unstructured":"Delessert A, Espa F, Rossetti A, Lavigne G, Tafti M, Heinzer R (2010) Pulse wave amplitude drops during sleep are reliable surrogate markers of changes in cortical activity. Sleep 33:1687\u20131928","journal-title":"Sleep"},{"key":"1699_CR9","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1046\/j.1365-2869.1998.00092.x","volume":"7","author":"DJ Pitson","year":"1998","unstructured":"Pitson DJ, Stradling JR (1998) Autonomic markers of arousal during sleep in patients undergoing investigation for obstructive sleep apnoea, their relationship to EEG arousals, respiratory events and subjective sleepiness. J Sleep Res 7:53\u201359","journal-title":"J Sleep Res"},{"key":"1699_CR10","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1097\/MCP.0b013e3283318585","volume":"15","author":"JL P\u00e9pin","year":"2009","unstructured":"P\u00e9pin JL, Tamisier R, Borel JC, Baguet JP, L\u00e9vy P (2009) A critical review of peripheral arterial tone and pulse transit time as indirect diagnostic methods for detecting sleep disordered breathing and characterizing sleep structure. Curr Opin Pulm Med 15:550\u2013558","journal-title":"Curr Opin Pulm Med"},{"issue":"136","key":"1699_CR11","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S1569-9048(03)00090-9","volume":"2003","author":"L Grote","year":"2003","unstructured":"Grote L, Zou D, Kraiczi H, Hedner J (2003) Finger plethysmography--a method for monitoring finger blood flow during sleep disordered breathing. Respir Physiol Neurobiol 2003(136):141\u2013152","journal-title":"Respir Physiol Neurobiol"},{"key":"1699_CR12","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s11325-005-0017-y","volume":"9","author":"J Haba-Rubio","year":"2005","unstructured":"Haba-Rubio J, Darbellay G, Herrmann FR, Frey JG, Fernandes A, Vesin JM, Thiran JP, Tschopp JM (2005) Obstructive sleep apnea syndrome: effect of respiratory events and arousal on pulse wave amplitude measured by photoplethysmography in NREM sleep. Sleep Breath 9:73\u201381","journal-title":"Sleep Breath"},{"key":"1699_CR13","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.sleep.2003.06.003","volume":"4","author":"H Adachi","year":"2003","unstructured":"Adachi H, Mikami A, Kumano-go T, Suganuma N, Matsumoto H, Shigedo Y, Sugita Y, Takeda M (2003) Clinical significance of pulse rate rise during sleep as a screening marker for the assessment of sleep fragmentation in sleep-disordered breathing. Sleep Med 4:537\u2013542","journal-title":"Sleep Med"},{"key":"1699_CR14","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s11325-007-0126-x","volume":"12","author":"A Zacharia","year":"2008","unstructured":"Zacharia A, Haba-Rubio J, Simon R, John G, Jordan P, Fernandes A, Gaspoz JM, JG F, Tschopp JM (2008) Sleep apnea syndrome: improved detection of respiratory events and cortical arousals using oxymetry pulse wave amplitude during polysomnography. Sleep Breath 12:33\u201338","journal-title":"Sleep Breath"},{"key":"1699_CR15","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1002\/mus.24457","volume":"51","author":"EA Piccione","year":"2015","unstructured":"Piccione EA, Sletten DM, Staff NP, Low PA (2015) Autonomic system and amyotrophic lateral sclerosis. Muscle Nerve 51:676\u2013679","journal-title":"Muscle Nerve"},{"key":"1699_CR16","unstructured":"Iber C, Ancoli-Israel S, Chesson A, Quan S. F. (2007) American Academy of sleep medicine. The AASM manual for the scoring of sleep and associated events: rules, Terminology and technical specifications, 1st ed. American Academy of Sleep Medicine, Westchester, IL"},{"key":"1699_CR17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.5664\/jcsm.2148","volume":"8","author":"D Sommermeyer","year":"2012","unstructured":"Sommermeyer D, Zou D, Grote L, Hedner J (2012) Detection of sleep disordered breathing and its central\/obstructive character using nasal cannula and finger pulse oximeter. J Clin Sleep Med 8:527\u2013533","journal-title":"J Clin Sleep Med"},{"key":"1699_CR18","doi-asserted-by":"crossref","unstructured":"Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996) Circulation 93:1043\u20131065","DOI":"10.1161\/01.CIR.93.5.1043"},{"key":"1699_CR19","doi-asserted-by":"publisher","first-page":"3224","DOI":"10.1161\/01.CIR.96.9.3224","volume":"96","author":"DL Eckberg","year":"1997","unstructured":"Eckberg DL (1997) Sympathovagal balance: a critical appraisal. Circulation 96:3224\u20133232","journal-title":"Circulation"},{"key":"1699_CR20","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1016\/S1388-2457(00)00363-1","volume":"111","author":"E Sforza","year":"2000","unstructured":"Sforza E, Jouny C, Ibanez V (2000) Cardiac activation during arousal in humans: further evidence for hierarchy in the arousal response. Clin Neurophysiol 111:1611\u20131619","journal-title":"Clin Neurophysiol"},{"key":"1699_CR21","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1016\/j.rmed.2013.10.010","volume":"107","author":"D Adler","year":"2013","unstructured":"Adler D, Bridevaux PO, Contal O, Georges M, Dupuis-Lozeron E, Claudel E, P\u00e9pin JL, Janssens JP (2013) Pulse wave amplitude reduction: a surrogate marker of micro-arousals associated with respiratory events occurring under non-invasive ventilation? Respir Med 107:2053\u20132060","journal-title":"Respir Med"},{"key":"1699_CR22","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/sleep\/30.1.43","volume":"30","author":"E Sforza","year":"2007","unstructured":"Sforza E, Pichot V, Cervena K, Barth\u00e9l\u00e9my JC, Roche F (2007) Cardiac variability and heart-rate increment as a marker of sleep fragmentation in patients with a sleep disorder: a preliminary study. Sleep 30:43\u201351","journal-title":"Sleep"},{"key":"1699_CR23","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1088\/0967-3334\/36\/4\/659","volume":"36","author":"L Dalla Vecchia","year":"2015","unstructured":"Dalla Vecchia L, De Maria B, Marinou K, Sideri R, Lucini A, Porta A, Mora G (2015) Cardiovascular neural regulation is impaired in amyotrophic lateral sclerosis patients. A study by spectral and complexity analysis of cardiovascular oscillations. Physiol Meas 36:659\u2013670","journal-title":"Physiol Meas"},{"issue":"5","key":"1699_CR24","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0924-980X(98)00035-6","volume":"109","author":"D Linden","year":"1998","unstructured":"Linden D, Diehl RR, Berlit P (1998) Reduced baroreflex sensitivity and cardio respiratory transfer in amyotrophic lateral sclerosis. Electroencephalogr Clin Neurophysiol 109(5):387\u2013390","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"1699_CR25","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.jns.2004.08.006","volume":"227","author":"K Shindo","year":"2004","unstructured":"Shindo K, Shimokawa C, Watanabe H, Iida H, Ohashi K, Nitta K, Nagasaka T, Tsunoda S, Shiozawa Z (2004) Chronological changes of sympathetic outflow to muscles in amyotrophic lateral sclerosis. J Neurol Sci 227:79\u201384","journal-title":"J Neurol Sci"},{"key":"1699_CR26","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/BF01826200","volume":"5","author":"T Shimizu","year":"1995","unstructured":"Shimizu T, Hayashi H, Hayashi M, Kato S, Tanabe H (1995) Hyposensitivity of peripheral alpha-adrenoceptors in respirator-dependent amyotrophic lateral sclerosis assessed by intravenous norepinephrine infusion. Clin Auton Res 5:165\u2013169","journal-title":"Clin Auton Res"},{"key":"1699_CR27","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1002\/mus.880160907","volume":"16","author":"C Dettmers","year":"1993","unstructured":"Dettmers C, Fatepour D, Faust H, Jerusalem F (1993) Sympathetic skin response abnormalities in amyotrophic lateral sclerosis. Muscle Nerve 16:930\u2013934","journal-title":"Muscle Nerve"},{"key":"1699_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1080\/146608299300079484","volume":"1","author":"M Toepfer","year":"1999","unstructured":"Toepfer M, Folwaczny C, Klauser A, Riepl RL, M\u00fcller-Felber W, Pongratz D (1999) Gastrointestinal dysfunction in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:15\u201319","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"1699_CR29","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1111\/resp.12836","volume":"21","author":"G Crescimanno","year":"2016","unstructured":"Crescimanno G, Greco F, Arrisicato S, Morana N, Marrone O (2016) Effects of positive end expiratory pressure administration during non-invasive ventilation in patients affected by amyotrophic lateral sclerosis: a randomized crossover study. Respirology 21:1307\u20131313","journal-title":"Respirology"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-018-1699-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11325-018-1699-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-018-1699-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T16:35:23Z","timestamp":1604680523000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11325-018-1699-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,24]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["1699"],"URL":"https:\/\/doi.org\/10.1007\/s11325-018-1699-2","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,24]]},"assertion":[{"value":"12 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the ethics committee \"Palermo 2 Azienda Ospedaliera Villa Sofia-Cervello\". All procedures performed in this study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}