{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T02:12:51Z","timestamp":1779329571454,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T00:00:00Z","timestamp":1568419200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T00:00:00Z","timestamp":1568419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s11325-019-01939-8","type":"journal-article","created":{"date-parts":[[2019,10,26]],"date-time":"2019-10-26T00:07:31Z","timestamp":1572048451000},"page":"995-999","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Autonomic dysfunction in restless legs syndrome"],"prefix":"10.1007","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5338-3901","authenticated-orcid":false,"given":"Yuksel","family":"Erdal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozlem","family":"Akdogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mecbure","family":"Nalbantoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokce","family":"Kavasoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ufuk","family":"Emre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,9,14]]},"reference":[{"key":"1939_CR1","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","volume":"15","author":"RP Allen","year":"2014","unstructured":"Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB, International Restless Legs Syndrome Study Group (2014) Restless legs syndrome\/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med 15:860\u2013873","journal-title":"Sleep Med"},{"key":"1939_CR2","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1136\/practneurol-2017-001762","volume":"17","author":"S Wijemanne","year":"2017","unstructured":"Wijemanne S, Ondo W (2017) Restless legs syndrome: clinical features, diagnosis and a practical approach to management. Pract Neurol 17:444\u2013452","journal-title":"Pract Neurol"},{"key":"1939_CR3","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.smrv.2011.05.002","volume":"16","author":"MM Ohayon","year":"2012","unstructured":"Ohayon MM, O'Hara R, Vitiello MV (2012) Epidemiology of restless legs syndrome: a synthesis of the literature. Sleep Med Rev 16:283\u2013295","journal-title":"Sleep Med Rev"},{"key":"1939_CR4","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s00415-009-0134-9","volume":"256","author":"C Trenkwalder","year":"2009","unstructured":"Trenkwalder C, Hogl B, Winkelmann J (2009) Recent advances in the diagnosis, genetics and treatment of restless legs syndrome. J Neurol 256:539\u2013553","journal-title":"J Neurol"},{"key":"1939_CR5","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/B978-0-12-804074-4.00018-2","volume-title":"Sleep and neurologic disease","author":"MG Miglis","year":"2017","unstructured":"Miglis MG (2017) Sleep and the autonomic nervous system. In: Sleep and neurologic disease, pp 227\u2013241"},{"key":"1939_CR6","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/s10286-018-0560-9","volume":"28","author":"AM Fink","year":"2018","unstructured":"Fink AM, Bronas UG, Calik MW (2018) Autonomic regulation during sleep and wakefulness: a review with; implications for defning the pathophysiology of neurological disorders. Clin Auton Res 28:509\u2013518","journal-title":"Clin Auton Res"},{"key":"1939_CR7","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.parkreldis.2010.08.022","volume":"17","author":"S Jain","year":"2011","unstructured":"Jain S (2011) Multi-organ autonomic dysfunction in Parkinson disease. Parkinsonism Relat Disord 17:77\u201383","journal-title":"Parkinsonism Relat Disord"},{"key":"1939_CR8","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1016\/j.sleep.2013.08.781","volume":"14","author":"N Shneyder","year":"2013","unstructured":"Shneyder N, Adler CH, Hentz JG, Shill H, Caviness JN, Sabbagh MN, Beach TG, Driver-Dunckley E (2013) Autonomic complaints in patients with restless legs syndrome. Sleep Med 14:1413\u20131416","journal-title":"Sleep Med"},{"key":"1939_CR9","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.clinph.2010.07.005","volume":"122","author":"B Isak","year":"2011","unstructured":"Isak B, Uluc K, Salcini C, Agan K, Tanridag T, Us O (2011) A neurophysiological approach to the complex organisation of the spine: f-wave duration and the cutaneous silent period in restless legs syndrome. Clin Neurophysiol 122:383\u2013390","journal-title":"Clin Neurophysiol"},{"key":"1939_CR10","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1016\/j.sleep.2014.06.022","volume":"15","author":"F Izzi","year":"2014","unstructured":"Izzi F, Placidi F, Romigi A, Lauretti B, Marfia GA, Mercuri NB, Marciani MG, Rocchi C (2014) Is autonomic nervous system involved in restless legs syndrome during wakefulness? Sleep Med 15:1392\u20131397","journal-title":"Sleep Med"},{"key":"1939_CR11","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.neucli.2009.06.003","volume":"39","author":"L Tyvaert","year":"2009","unstructured":"Tyvaert L, Laureau E, Hurtevent JP, Hurtevent JF, Derambure P, Monaca C (2009) A-delta and C-fibres function in primary restless legs syndrome. Neurophysiol Clin 39:267\u2013274","journal-title":"Neurophysiol Clin"},{"key":"1939_CR12","doi-asserted-by":"publisher","first-page":"260","DOI":"10.4103\/0972-2327.104332","volume":"15","author":"G Shukla","year":"2012","unstructured":"Shukla G, Goyal V, Srivastava A, Behari M (2012) Quantitative thermal sensory testing and sympathetic skin response in primary restless legs syndrome - a prospective study on 57 Indian patients. Ann Indian Acad Neurol 15:260\u2013262","journal-title":"Ann Indian Acad Neurol"},{"key":"1939_CR13","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1002\/mds.20153","volume":"19","author":"M Visser","year":"2004","unstructured":"Visser M, Marinus J, Stiggelbout A, Van Hilten JJ (2004) Assessment of autonomic dysfunction in Parkinson\u2019s disease: the SCOPA-AUT. Mov Disord 19:1306\u20131312","journal-title":"Mov Disord"},{"key":"1939_CR14","unstructured":"Yasar H, Senol MG, Tasdemir S et al (2016) Validity and reliability of the Turkish version of the scales for outcomes in Parkinson\u2019s disease-autonomic questionnaire (SCOPA-AUT). Mov Disord 31(suppl 2):516-517"},{"key":"1939_CR15","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S1389-9457(02)00258-7","volume":"4","author":"AS Walters","year":"2003","unstructured":"Walters AS et al (2003) Validation of the international restless legs syndrome study group rating scale for restless legs syndrome. Sleep Med 4:121\u2013132","journal-title":"Sleep Med"},{"key":"1939_CR16","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1212\/WNL.55.8.1115","volume":"55","author":"M Polydefkis","year":"2000","unstructured":"Polydefkis M, Allen RP, Hauer P, Earley CJ, Griffin JW, McArthur JC (2000) Subclinical sensory neuropathy in late-onset restless legs syndrome. Neurology 55:1115\u20131121","journal-title":"Neurology"},{"key":"1939_CR17","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1002\/mds.870100103","volume":"10","author":"S Iannaccone","year":"1995","unstructured":"Iannaccone S, Zucconi M, Marchettini P, Ferini-Strambi L, Nemni R, Quattrini A, Palazzi S, Lacerenza M, Formaglio F, Smirne S (1995) Evidence of peripheral axonal neuropathy in primary restless legs syndrome. Mov Disord 10:2\u20139","journal-title":"Mov Disord"},{"key":"1939_CR18","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1002\/mds.23742","volume":"26","author":"A Pavy-Le Traon","year":"2011","unstructured":"Pavy-Le Traon A, Amarenco G, Duerr S et al (2011) The movement disorders task force review of dysautonomia rating scales in Parkinson\u2019s disease with regard to symptoms of orthostatic hypotension. Mov Disord 26:1985\u20131992","journal-title":"Mov Disord"},{"key":"1939_CR19","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.parkreldis.2011.12.009","volume":"18","author":"N Damon-Perri\u00e8re","year":"2012","unstructured":"Damon-Perri\u00e8re N, Foubert-Samier A, De Cock VC et al (2012) Assessment of the Scopa-Aut questionnaire in multiple system atrophy: relation to UMSARS scores and progression over time. Parkinsonism Relat Disord 18:612\u2013615","journal-title":"Parkinsonism Relat Disord"},{"key":"1939_CR20","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1002\/mds.20782","volume":"21","author":"S Papapetropoulos","year":"2006","unstructured":"Papapetropoulos S, Argyriou AA, Chroni E (2006) No correlation between the clinical severity of autonomic symptoms (SCOPA-AUT) and electrophysiological test abnormalities in advanced Parkinson\u2019s disease. Mov Disord 21:430\u2013431","journal-title":"Mov Disord"},{"key":"1939_CR21","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1007\/s00415-014-7317-8","volume":"261","author":"L Ferini-Strambi","year":"2014","unstructured":"Ferini-Strambi L, Oertel W, Dauvilliers Y, Postuma RB, Marelli S, Iranzo A, Arnulf I, Birgit H, Manni R, Miyamoto T, Fantini ML, Puligheddu M, Jennum P, Sonka K, Santamaria J, Zucconi M, Rancoita PMV, Leu-Semenescu S, Frauscher B, Terzaghi M, Miyamoto M, Unger M, Stiasny-Kolster K, Desautels A, Wolfson C, Pelletier A, Montplaisir J (2014) Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case-control study. J Neurol 261:1112\u20131118","journal-title":"J Neurol"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-019-01939-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11325-019-01939-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-019-01939-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T23:34:24Z","timestamp":1599953664000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11325-019-01939-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,14]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["1939"],"URL":"https:\/\/doi.org\/10.1007\/s11325-019-01939-8","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,14]]},"assertion":[{"value":"10 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}