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However, it is unknown whether the type and severity of respiratory events are linked to stroke or transient ischemic attack (TIA). Thus, we investigate whether the characteristics of individual respiratory events differ between patients experiencing\u00a0TIA or acute ischemic stroke and matched patients with clinically suspected sleep-disordered breathing.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Polygraphic data of 77 in-patients with acute ischemic stroke (<jats:italic>n<\/jats:italic>\u2009=\u200949) or\u00a0TIA (<jats:italic>n<\/jats:italic>\u2009=\u200928) were compared to age, gender, and BMI-matched patients with suspected sleep-disordered breathing and no cerebrovascular disease. Along with conventional diagnostic parameters (e.g., apnea-hypopnea index), durations and severities of individual apneas, hypopneas and desaturations were compared between the groups separately for ischemic stroke and TIA\u00a0patients.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Stroke and\u00a0TIA patients had significantly shorter apneas and hypopneas (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) compared to matched reference patients. Furthermore, stroke patients had more central apnea events (<jats:italic>p<\/jats:italic>\u2009=\u20090.007) and\u00a0a trend for higher apnea\/hypopnea number ratios (<jats:italic>p<\/jats:italic>\u2009=\u20090.091). The prevalence of\u00a0OSA (apnea-hypopnea index \u2265\u20095) was 90% in acute stroke patients and 79% in transient ischemic attack patients.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Stroke patients had different characteristics of respiratory events, i.e., their polygraphic phenotype of\u00a0OSA\u00a0differs compared to matched reference patients. The observed differences in polygraphic features might indicate that stroke and TIA patients suffer from OSA phenotype recently associated with increased cardiovascular mortality. Therefore, optimal diagnostics and treatment require routine OSA screening in patients with acute cerebrovascular disease, even without previous suspicion of OSA.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s11325-019-02010-2","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T11:02:49Z","timestamp":1578999769000},"page":"1495-1505","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea"],"prefix":"10.1007","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7918-9373","authenticated-orcid":false,"given":"Akseli","family":"Leino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna","family":"Westeren-Punnonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juha","family":"T\u00f6yr\u00e4s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami","family":"Myllymaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Lepp\u00e4nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salla","family":"Yl\u00e4-Herttuala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anu","family":"Muraja-Murro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Mari","family":"Kantanen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaana","family":"Autere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pekka","family":"J\u00e4k\u00e4l\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esa","family":"Mervaala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Myllymaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,14]]},"reference":[{"key":"2010_CR1","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1164\/rccm.200911-1746OC","volume":"182","author":"S Redline","year":"2010","unstructured":"Redline S, Yenokyan G, Gottlieb D, Shahar E, O'Connor G, Resnick H, Diener-West M, Sanders M, Wolf P, Geraghty E, Ali T, Lebowitz M, Punjabi N (2010) Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. 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The Research Ethics Committee of Hospital District of Northern Savo, Kuopio, Finland, gave a favorable opinion for the collection and use of the datasets (50\/2014).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants recruited for this the study\u00a0or their next of kin. In this type of study, formal consent for retrospective data is not required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}