{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T23:17:21Z","timestamp":1714519041999},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Adaptive servo-ventilation (ASV) is a therapy designed for patients with central sleep apnea (CSA) and Cheyne Stokes respiration. The aim of this study was to find predictors of ASV usage in patients with CSA in a routine sleep clinic cohort.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this retrospective study, consecutive patients in whom ASV therapy was initiated at the University Hospital Regensburg between 2011 and 2015, were analyzed. Analysis included polysomnographies of diagnostic and ASV initiation nights, a phone questionnaire on ASV usage, readout of the ASV device 1 month after initiation (\u201cearly ASV usage,\u201d 1 month after ASV initiation), and the readout of the last month before a reappointment date set in 2015 (\u201clate ASV usage,\u201d median 17 months after ASV initiation).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In 69 consecutive patients, the mean early and late ASV usage per night was 4.8 \u00b1 2.5 h and 4.1 \u00b1 3.0 h, respectively. Seventeen months after initiation, 57% of patients used the device \u2265 4 h per night, and\u00a0of those 91% reported a subjective benefit from ASV therapy. Early ASV usage was significantly associated with late ASV usage (univariable regression: Beta 0.8, 95%CI [0.6; 1.0] <jats:italic>p<\/jats:italic> &lt; 0.001). In multivariable regression analysis, short duration of slow wave sleep (N3) during diagnostic polysomnography (Beta \u2212 6.2, 95%CI [\u2212 11.0; \u2212 1.5]; <jats:italic>p<\/jats:italic> = 0.011) and subjective benefit from ASV (Beta 174.0, 95%CI [68.6; 279.5]; <jats:italic>p<\/jats:italic> = 0.002) were significantly associated with longer late ASV usage.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Early ASV usage predicts late ASV usage. In addition, low slow wave sleep before ASV initiation and subjective benefit from ASV may contribute to higher late ASV usage.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11325-020-02182-2","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T09:03:55Z","timestamp":1599123835000},"page":"1135-1145","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adaptive servo-ventilation in patients with chronic heart failure and sleep disordered breathing: predictors of usage"],"prefix":"10.1007","volume":"25","author":[{"given":"Leonie","family":"Kolb","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Arzt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Stadler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Heider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars S.","family":"Maier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"issue":"4","key":"2182_CR1","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1164\/ajrccm.164.4.9908114","volume":"164","author":"H Teschler","year":"2001","unstructured":"Teschler H, Dohring J, Wang YM et al (2001) Adaptive pressure support servo-ventilation: a novel treatment for Cheyne-Stokes respiration in heart failure. 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Arzt reports grants and personal fees from Philips Respironics and ResMed; grants from the ResMed Foundation; and personal fees from Novartis, BresoTec, Boehringer-Ingelheim, Inspire, JAZZ Pharmaceuticals, and NRI outside the submitted work. All other authors report no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This retrospective analysis was approved by the Ethics Committee of the University of Regensburg (approval no. 15-101-0255) and was conducted in accordance with the principles of Good Clinical Practice and the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The requirement for informed consent was waived because of the retrospective study design.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}