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Ten patients\u00a0were recruited and had polysomnography. A program written in Python was used to investigate the efficacy of the program\u2019s algorithms and the relationship between variables in polysomnography (sleep stage, apnea-hypopnea index or\u00a0AHI, oxygen-related variables) and mouth puffing signals (MPSs). The video recording was used to validate the program. Bland\u2013Altman plot, correlations, independent sample <jats:italic>t<\/jats:italic>-test, and ANOVA were analyzed by SPSS 24.0. <\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Patients were found to mouth puff when they sleep with their mouths taped. An MPD was able to detect the signals of mouth puffing. Mouth puffing signals were noted and categorized into four types of MPSs by our algorithms. MPSs were found to be significantly related to relative OSA indices. When all participants\u2019 data were divided into minutes, intermittent mouth puffing (IMP) was found to be significantly different from non-mouth puffing in AHI, oxygen desaturation index (ODI), and time of oxygen saturation under 90% (T90) (AHI: 0.75 vs. 0.31; ODI: 0.75 vs. 0.30; T90: 5.52 vs. 1.25; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Participants with severe OSA showed a higher IMP percentage compared to participants with mild to moderate OSA and the\u00a0control group (severe: 38%, mild-to-moderate: 65%, control: 95%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This study established a simple way to detect mouth puffing phenomena when\u00a0patients were mouth-taped during sleep, and the signals were classified into four types of MPSs. We propose that MPSs obtained from patients wearing the MPD can be used as a complement for clinicians to evaluate OSA.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11325-022-02588-0","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T22:02:31Z","timestamp":1647036151000},"page":"153-164","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Mouth puffing phenomena of patients\u00a0with obstructive sleep apnea when mouth-taped: device\u2019s efficacy confirmed with physical video observation"],"prefix":"10.1007","volume":"27","author":[{"given":"Je-Yang","family":"Jau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry B. J.","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lieber P. 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The study was approved by the Human Research Committee of the National Yang-Ming University, Taipei, Taiwan (project number YM107083E).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"M610717: Sleep-Disordered-Breathing Screening Equipment.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patents"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}