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As part of the study, written informed consent has been collected from all participants, detailing the purpose of the research, the process involved, and the rights and protections for participants. Moreover, the design and execution of this study strictly adhere to the principles outlined in the 1964 Helsinki Declaration and its subsequent amendments, as well as comply with Good Clinical Practice guidelines and current legal requirements. Additionally, the retrospective data analysis involved in this study has been reviewed and approved by the internal committee of the Neurobiological Function Laboratory of Hebei Province, China. This review process ensures the scientific validity and rationality of the research plan, with a focus on privacy protection and data security during data handling. Through these rigorous review and approval procedures, we have ensured the ethical, legal, and scientific integrity of the research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All authors hereby declare that there are no conflicts of economic interest related to external organizations or entities in this study. This means that the authors have not received any form of remuneration, educational grants, or other financial support, nor have they been part of any speaking panels or advisory committees that might affect the objectivity of the research findings. Additionally, the authors do not hold any form of membership, employment, shares, or other interests that could constitute a conflict of interest. They have also not engaged in providing expert testimony or arranging patent licensing, ensuring the independence and objectivity of the research. The authors guarantee that their contributions are based on scientific principles and objective data, unaffected by any external economic interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}