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MMA was performed with previously published nasal modifications to help mitigate negative sinonasal outcomes. Sino-nasal Outcome Test (SNOT-22) and Nasal Obstruction Symptom Evaluation Survey (NOSE) were collected preoperatively, and one and three months postoperatively. Repeated measures ANOVAs with a Bonferroni adjustment were performed for total score, total sinonasal score (sum of questions 1\u201312), and each symptom. Both <jats:italic>p<\/jats:italic>-values and partial eta squared (n<jats:sub>p<\/jats:sub>\n              <jats:sup>2<\/jats:sup>) were reported.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Twenty patients were included. Median age was 50.7 years (range 31\u201365), with 20.0% being female. Preoperative AHI (65.1\u2009\u00b1\u200928.9) and SpO2 Nadir (78.0% [69.0\u201382.0]) improved to 12.1\u2009\u00b1\u200912.1 and 86.0\u2009\u00b1\u20093.2%. NOSE significantly decreased at one month (55.9\u2009\u00b1\u200928.4 vs. 8.11\u2009\u00b1\u200912.0, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Total score and total sinonasal scores significantly decreased postoperatively (49.0\u2009\u00b1\u200921.6 vs. 18.1\u2009\u00b1\u200917.4 vs. 12.5\u2009\u00b1\u200914.1, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; 17.3\u2009\u00b1\u200912.5 vs. 9.2\u2009\u00b1\u20099.3 vs. 6.3\u2009\u00b1\u20097.3, <jats:italic>p<\/jats:italic>\u2009=\u20090.003) with MMA having large effects on both variables (n<jats:sub>p<\/jats:sub>\n              <jats:sup>2<\/jats:sup>=0.72 and 0.35, respectively). MMA had large significant effects on improvement in need to blow nose, nasal blockage, sneezing, runny nose, cough, post-nasal discharge, dizziness, and ear pain at one and three months postoperatively. Facial pain\/pressure significantly worsened at one-month but then improved to baseline at three months postoperatively ((1.2\u2009\u00b1\u20091.4 vs. 1.9\u2009\u00b1\u20091.5 vs. 1.2\u2009\u00b1\u20091.4, <jats:italic>p<\/jats:italic>\u2009=\u20090.026).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Patients who underwent preservation MMA did not show evidence of worsening sinonasal function, with some evidence that sinonasal function may improve after MMA at three months postoperatively. Long-term follow-up with more patients is needed to support these findings.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s11325-025-03262-x","type":"journal-article","created":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T11:36:46Z","timestamp":1739014606000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of nasal modifications on sinonasal function after maxillomandibular advancement for obstructive sleep apnea"],"prefix":"10.1007","volume":"29","author":[{"given":"Nicolas S.","family":"Poupore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2588-8355","authenticated-orcid":false,"given":"Mohamed","family":"Abdelwahab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,8]]},"reference":[{"key":"3262_CR1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1001\/jamaoto.2015.2678","volume":"142","author":"S Zaghi","year":"2016","unstructured":"Zaghi S, Holty JE, Certal V, Abdullatif J, Guilleminault C, Powell NB, Riley RW et al (2016) Maxillomandibular Advancement for treatment of obstructive sleep apnea: a Meta-analysis. 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