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Both EDS and OSA affect, and are affected by, physical activity (PA). This study explores physical activity patterns in OSA patients and the association between activity and EDS.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This is a retrospective analysis of cross-sectional data from the Sydney Sleep Biobank, which recruited sleep clinic patients between August 2018 and June 2022. Participants aged\u2009&gt;\u200918 years with untreated OSA were included, while those with other sleep disorders or whose medication\/work affected sleepiness were excluded. PA was assessed with the International Physical Activity Questionnaire (IPAQ), with intensity quantified by metabolic equivalent of task (MET). Subjective daytime sleepiness with quantified by the Epworth Sleepiness Scale (ESS).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Of 487 patients with OSA, 21% reported low (&lt;\u2009600 MET-min\/week), 32% medium (600\u20132999 MET min\/week), and 47% high PA (\u2009&gt;\u2009=\u20093000 MET-min\/week). Participants with mild OSA were the most likely to be in the high PA group. ESS was not significantly associated with physical activity nor OSA severity, after adjustment for sex, age, body mass index, and sleep duration. Consideration of a potential interaction between physical activity and OSA severity did not change these results. However, in subgroup analysis of women only, severe OSA and medium and high levels of PA were linked to higher ESS scores.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Greater physical activity was associated with higher daytime sleepiness in women, but not men. However, further research is needed to reproduce these findings using objective measures of physical activity and to examine if physical activity has direct benefits for daytime symptoms of OSA beyond sleepiness.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s11325-025-03314-2","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T13:54:30Z","timestamp":1743861270000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patterns of physical activity in Obstructive Sleep Apnoea and their association with sleepiness"],"prefix":"10.1007","volume":"29","author":[{"given":"By Jack","family":"Callum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Sun","family":"Bin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Piper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Kairaitis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Wheatley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"de Chazal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendon J.","family":"Yee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Stamatakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-4924","authenticated-orcid":false,"given":"Peter A.","family":"Cistulli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Sydney Sleep Biobank Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"issue":"2","key":"3314_CR1","doi-asserted-by":"publisher","first-page":"335","DOI":"10.5664\/jcsm.7640","volume":"15","author":"SP Patil","year":"2019","unstructured":"Patil SP, Ayappa IA, Caples SM, Kimoff RJ, Patel SR, Harrod CG (2019) Treatment of adult obstructive sleep apnea with positive airway pressure: an American academy of sleep medicine clinical practice guideline. 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Sleep Med Rev 60:101535","journal-title":"Sleep Med Rev"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-025-03314-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11325-025-03314-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-025-03314-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T13:21:42Z","timestamp":1748006502000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11325-025-03314-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,4]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["3314"],"URL":"https:\/\/doi.org\/10.1007\/s11325-025-03314-2","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"type":"print","value":"1520-9512"},{"type":"electronic","value":"1522-1709"}],"subject":[],"published":{"date-parts":[[2025,4,4]]},"assertion":[{"value":"21 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 February 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed were in accordance with the ethical standards of the institutional and\/or national research committee (Northern Sydney Local Health District) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Patients provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Data for this study were collected as part of the Sydney Sleep Biobank (SSB). The SSB includes polysomnography and a comprehensive questionnaire collected from patients of three tertiary hospitals across Sydney (Royal North Shore Hospital, Royal Prince Alfred Hospital and Westmead Hospital) and the Westmead Institute for Medical Research in Australia.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institution where work was performed"}},{"value":"PAC has an appointment to an endowed academic Chair at the University of Sydney that was established from ResMed funding, has received research support from ResMed and SomnoMed, and is a consultant to ResMed, SomnoMed, Signifier Medical Technologies, Bayer, and Sunrise Medical. All other authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers\u2019 bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"147"}}