{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T09:36:29Z","timestamp":1784021789781,"version":"3.55.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s11325-025-03538-2","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T01:18:12Z","timestamp":1763169492000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of comorbid obstructive sleep apnea on sleep efficiency and architecture in patients with periodic limb movements: an exploratory study"],"prefix":"10.1007","volume":"29","author":[{"given":"Matilde","family":"Ferreira de Almeida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Amorim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Carlos","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Rocha e Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Drummond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"On behalf of CRISV (Centro de Responsabilidade Integrada do Sono e Ventila\u00e7\u00e3o)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,15]]},"reference":[{"issue":"11","key":"3538_CR1","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1007\/s11910-023-01309-8","volume":"23","author":"A Sen","year":"2023","unstructured":"Sen A, Tai XY, Springer (2023) Sleep duration and executive function in adults. Curr Neurol Neurosci Rep 23(11):801\u2013813. https:\/\/doi.org\/10.1007\/s11910-023-01309-8","journal-title":"Curr Neurol Neurosci Rep"},{"key":"3538_CR2","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-019-0543-8","author":"A Stefani","year":"2019","unstructured":"Stefani A, H\u00f6gl B, Current Science Inc. (2019) Diagnostic criteria, differential diagnosis, and treatment of minor motor activity and less well-known movement disorders of sleep. Curr Treat Options Neurol. https:\/\/doi.org\/10.1007\/s11940-019-0543-8","journal-title":"Curr Treat Options Neurol"},{"key":"3538_CR3","unstructured":"American Academy of Sleep Medicine (2014) International classification of sleep disorders (ICSD-3). 3rd ed. (Darien I, ed.). Darien, IL: American Academy of Sleep Medicine"},{"issue":"11","key":"3538_CR4","doi-asserted-by":"publisher","first-page":"6476","DOI":"10.21037\/jtd-21-1353","volume":"13","author":"P Drakatos","year":"2021","unstructured":"Drakatos P, Olaithe M, Verma D et al (2021) Periodic limb movements during sleep: a narrative review. J Thorac Dis 13(11):6476\u20136494. https:\/\/doi.org\/10.21037\/jtd-21-1353","journal-title":"J Thorac Dis"},{"issue":"3","key":"3538_CR5","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1002\/ana.24593","volume":"79","author":"J Haba-Rubio","year":"2016","unstructured":"Haba-Rubio J, Marti-Soler H, Marques-Vidal P et al (2016) Prevalence and determinants of periodic limb movements in the general population. Ann Neurol 79(3):464\u2013474. https:\/\/doi.org\/10.1002\/ana.24593","journal-title":"Ann Neurol"},{"issue":"3","key":"3538_CR6","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.amjmed.2018.09.021","volume":"132","author":"M K. Pavlova","year":"2019","unstructured":"K. Pavlova M, Latreille V (2019) Sleep disorders. Am J Med 132(3):292\u2013299. https:\/\/doi.org\/10.1016\/j.amjmed.2018.09.021. (Elsevier Inc)","journal-title":"Am J Med"},{"issue":"1","key":"3538_CR7","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/mds.870120111","volume":"12","author":"J Montplaisir","year":"1997","unstructured":"Montplaisir J, Boucher S, Poirier G, Lavigne G, Lapierre O, Lesp\u00e9rance P (1997) Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria. Mov Disord 12(1):61\u201365","journal-title":"Mov Disord"},{"key":"3538_CR8","volume-title":"The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Version 3","author":"M Troester","year":"2023","unstructured":"Troester M, Quan S, Berry R (2023) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Version 3. American Academy of Sleep Medicine, Darien, IL"},{"issue":"8","key":"3538_CR9","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.5665\/sleep.1988","volume":"35","author":"RN Aurora","year":"2012","unstructured":"Aurora RN, Kristo DA, Bista SR et al (2012) The treatment of restless legs syndrome and periodic limb movement disorder in adults - an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses. Sleep 35(8):1039\u20131062. https:\/\/doi.org\/10.5665\/sleep.1988","journal-title":"Sleep"},{"key":"3538_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-017-0446-5","author":"M Figorilli","year":"2017","unstructured":"Figorilli M, Puligheddu M, Congiu P, Ferri R, Current Science Inc. (2017) The clinical importance of periodic leg movements in sleep. Curr Treat Options Neurol. https:\/\/doi.org\/10.1007\/s11940-017-0446-5","journal-title":"Curr Treat Options Neurol"},{"issue":"5","key":"3538_CR11","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/S0022-3999(04)00020-0","volume":"56","author":"M Hornyak","year":"2004","unstructured":"Hornyak M, Trenkwalder C (2004) Restless legs syndrome and periodic limb movement disorder in the elderly. J Psychosom Res 56(5):543\u2013548. https:\/\/doi.org\/10.1016\/S0022-3999(04)00020-0","journal-title":"J Psychosom Res"},{"issue":"3","key":"3538_CR12","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx013","volume":"40","author":"T Kendzerska","year":"2017","unstructured":"Kendzerska T, Kamra M, Murray BJ, Boulos MI (2017) Incident cardiovascular events and death in individuals with restless legs syndrome or periodic limb movements in sleep: a systematic review. Sleep 40(3):zsc013. https:\/\/doi.org\/10.1093\/sleep\/zsx013","journal-title":"Sleep"},{"issue":"17","key":"3538_CR13","doi-asserted-by":"publisher","first-page":"E1820","DOI":"10.1212\/WNL.0000000000008844","volume":"94","author":"R Budhiraja","year":"2020","unstructured":"Budhiraja R, Javaheri S, Pavlova MK, Epstein LJ, Omobomi O, Quan SF (2020) Prevalence and correlates of periodic limb movements in OSA and the effect of CPAP therapy. Neurology 94(17):E1820\u2013E1827. https:\/\/doi.org\/10.1212\/WNL.0000000000008844","journal-title":"Neurology"},{"key":"3538_CR14","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.sleep.2017.09.014","volume":"41","author":"J Haba-Rubio","year":"2018","unstructured":"Haba-Rubio J, Marti-Soler H, Tobback N et al (2018) Clinical significance of periodic limb movements during sleep: the hypnolaus study. Sleep Med 41:45\u201350. https:\/\/doi.org\/10.1016\/j.sleep.2017.09.014","journal-title":"Sleep Med"},{"key":"3538_CR15","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.031630","author":"A Zinchuk","year":"2024","unstructured":"Zinchuk A, Srivali N, Qin L et al (2024) Association of periodic limb movements and obstructive sleep apnea with risk of cardiovascular disease and mortality. J Am Heart Assoc. https:\/\/doi.org\/10.1161\/JAHA.123.031630","journal-title":"J Am Heart Assoc"},{"issue":"8","key":"3538_CR16","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1164\/ajrccm.164.8.2011062","volume":"164","author":"RD Chervin","year":"2001","unstructured":"Chervin RD (2001) Periodic leg movements and sleepiness in patients evaluated for sleep-disordered breathing. Am J Respir Crit Care Med 164(8):1454\u20131458. https:\/\/doi.org\/10.1164\/ajrccm.164.8.2011062","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"3538_CR17","doi-asserted-by":"publisher","first-page":"217","DOI":"10.21053\/ceo.2024.00034","volume":"17","author":"JH Soh","year":"2024","unstructured":"Soh JH, Kang YJ, Yoon WH, Park CS, Shin HW (2024) Positional obstructive sleep apnea and periodic limb movements during sleep: a large multicenter study. Clin Exp Otorhinolaryngol 17(3):217\u2013225. https:\/\/doi.org\/10.21053\/ceo.2024.00034","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"3538_CR18","unstructured":"R Core Team (2024) R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. Preprint posted online 2024. https:\/\/www.R-project.org\/. Accessed 16 Feb 2025"},{"issue":"3","key":"3538_CR19","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.smrv.2005.12.003","volume":"10","author":"M Hornyak","year":"2006","unstructured":"Hornyak M, Feige B, Riemann D, Voderholzer U (2006) Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. Sleep Med Rev 10(3):169\u2013177. https:\/\/doi.org\/10.1016\/j.smrv.2005.12.003","journal-title":"Sleep Med Rev"},{"issue":"9","key":"3538_CR20","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.5665\/sleep\/31.9.1221","volume":"31","author":"H Scofield","year":"2008","unstructured":"Scofield H, Roth T, Drake C (2008) Periodic limb movements during sleep: population prevalence, clinical correlates, and racial differences. Sleep 31(9):1221\u20131227. https:\/\/doi.org\/10.5665\/sleep\/31.9.1221","journal-title":"Sleep"},{"key":"3538_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1378410","author":"C Seifen","year":"2024","unstructured":"Seifen C, Herrmann M, Pordzik J, Matthias C, Gouveris H (2024) Periodic limb movements in patients with suspected obstructive sleep apnea without comorbid conditions. Front Med. https:\/\/doi.org\/10.3389\/fmed.2024.1378410","journal-title":"Front Med"},{"issue":"1","key":"3538_CR22","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/s13311-021-01019-4","volume":"18","author":"TR Gossard","year":"2021","unstructured":"Gossard TR, Trotti LM, Videnovic A, St Louis EK, Springer Science and Business Media Deutschland GmbH (2021) Restless legs syndrome: contemporary diagnosis and treatment. Neurotherapeutics 18(1):140\u2013155. https:\/\/doi.org\/10.1007\/s13311-021-01019-4","journal-title":"Neurotherapeutics"},{"issue":"1","key":"3538_CR23","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.sleep.2010.03.019","volume":"12","author":"M Manconi","year":"2011","unstructured":"Manconi M, Ferri R, Zucconi M et al (2011) Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleep. Sleep Med 12(1):47\u201355. https:\/\/doi.org\/10.1016\/j.sleep.2010.03.019","journal-title":"Sleep Med"},{"issue":"11","key":"3538_CR24","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1161\/CIRCULATIONAHA.111.038968","volume":"124","author":"BB Koo","year":"2011","unstructured":"Koo BB, Blackwell T, Ancoli-Israel S, Stone KL, Stefanick ML, Redline S (2011) Association of incident cardiovascular disease with periodic limb movements during sleep in older men: outcomes of sleep disorders in older men (MrOS) study. Circulation 124(11):1223\u20131231. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.111.038968","journal-title":"Circulation"},{"issue":"6","key":"3538_CR25","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.sleep.2013.02.005","volume":"14","author":"MH Pennestri","year":"2013","unstructured":"Pennestri MH, Montplaisir J, Fradette L, Lavigne G, Colombo R, Lanfranchi PA (2013) Blood pressure changes associated with periodic leg movements during sleep in healthy subjects. Sleep Med 14(6):555\u2013561. https:\/\/doi.org\/10.1016\/j.sleep.2013.02.005","journal-title":"Sleep Med"},{"issue":"10","key":"3538_CR26","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1093\/qjmed\/hcx097","volume":"110","author":"CH Chou","year":"2017","unstructured":"Chou CH, Yin JH, Chen SY et al (2017) The potential impact of sleep-related movement disorders on stroke risk: a population-based longitudinal study. QJM Int J Med 110(10):649\u2013655. https:\/\/doi.org\/10.1093\/qjmed\/hcx097","journal-title":"QJM Int J Med"},{"issue":"3","key":"3538_CR27","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.sleep.2004.11.006","volume":"6","author":"E Sforza","year":"2005","unstructured":"Sforza E, Haba-Rubio J (2005) Night-to-night variability in periodic leg movements in patients with restless legs syndrome. Sleep Med 6(3):259\u2013267. https:\/\/doi.org\/10.1016\/j.sleep.2004.11.006","journal-title":"Sleep Med"},{"issue":"3","key":"3538_CR28","doi-asserted-by":"publisher","first-page":"497","DOI":"10.5665\/sleep.3484","volume":"37","author":"M Manconi","year":"2014","unstructured":"Manconi M, Zavalko I, Bassetti CL, Colamartino E, Pons M, Ferri R (2014) Respiratory-related leg movements and their relationship with periodic leg movements during sleep. Sleep 37(3):497\u2013504. https:\/\/doi.org\/10.5665\/sleep.3484","journal-title":"Sleep"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-025-03538-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11325-025-03538-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-025-03538-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:57:11Z","timestamp":1765810631000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11325-025-03538-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,15]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["3538"],"URL":"https:\/\/doi.org\/10.1007\/s11325-025-03538-2","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,15]]},"assertion":[{"value":"31 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted in compliance with ethical standards, and approval was obtained from the ethics committee of Hospital Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors further declare that no commercial or financial relationships exist that could be interpreted as a potential conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"357"}}