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Hypobaric hypoxia can exacerbate Sleep-Disordered Breathing (SDB), raising cardiovascular risk. Evaluating miners before altitude exposure may help identify SDB risk factors. We described nocturnal respiratory alterations during CIHH and the anthropometric and biological characteristics measured at sea level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      In this Cross-sectional study, nocturnal oximetry was performed in miners during high-altitude shifts. Blood samples, blood pressure, and anthropometric data were collected at sea level before ascent. Oxygen Desaturation Index (ODI)\u2009\u2265\u200915\/h and time spent with SpO\n                      <jats:sub>2<\/jats:sub>\n                      \u2009&lt;\u200985% were used as markers of SDB.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Over 36 months, 762 workers underwent nocturnal oximetry; 30 were female, mean age 45\u2009\u00b1\u200911 years, mean BMI 27\u2009\u00b1\u20093\u00a0kg\/m\u00b2. 203 workers had ODI\u2009\u2265\u200915\/h, and 559 showed nocturnal saturation\u2009&lt;\u200985% at altitude. Those with higher ODI had higher BMI, total cholesterol, triglycerides, uric acid, and blood pressure at sea level. Lowest SpO\u2082 values were described in miners with highest BMI, uric acid, and blood pressure. BMI remained the principal independent correlate of SDB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Obesity may represent a marker of vulnerability to nocturnal hypoxemia in workers exposed to CIHH Preventive strategies\u2014such as nutritional improvement, sleep apnea screening, and appropriate treatment\u2014are essential to improve health and working conditions under CIHH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11325-026-03751-7","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:03:27Z","timestamp":1783163007000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intermittent exposure to high-altitude work: nocturnal hypoxemia sea-level anthropometric and biochemical markers"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0007-9084","authenticated-orcid":false,"given":"Elisa","family":"Perger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Cantuarias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Ottolenghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morin","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Faini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Bilo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Pellizzari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Bertoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Lombardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Araya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perez","family":"Oscar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Parati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,4]]},"reference":[{"key":"3751_CR1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.965021","volume":"13","author":"M Furian","year":"2022","unstructured":"Furian M, Bitos K, Hartmann SE, Muralt L, Lichtblau M, Bader PR, Rawling JM, Ulrich S, Poulin MJ, Bloch KE (2022) Acute high altitude exposure, acclimatization and re-exposure on nocturnal breathing. 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