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The present study aimed to investigate the association between sleep patterns, inflammatory markers, and muscle function in older adults with and without sarcopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective controlled study included 63 older adults (&gt;\u200965 years), classified into sarcopenic (ES,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200931) and non-sarcopenic (ENS,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200932) groups. Assessments included body composition, muscle function, inflammatory biomarkers, mood, and sleep (polysomnography, actigraphy, questionnaires).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The ES showed lower handgrip strength (21.7\u2009\u00b1\u20097.6 vs. 27.6\u2009\u00b1\u200910.4 kg;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) and poorer physical performance (SPPB: 8.8\u2009\u00b1\u20092.3 vs. 11.2\u2009\u00b1\u20091.0;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). They presented reduced thigh extension torque (82.7\u2009\u00b1\u200935.1 vs. 113.0\u2009\u00b1\u200926.8 N\u00b7m;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) and flexion torque (44.4\u2009\u00b1\u200923.7 vs. 53.3\u2009\u00b1\u200916.0 N\u00b7m;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Sleep alterations included shorter total sleep time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), lower sleep efficiency (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), higher WASO (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and increased apnea-hypopnea index (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). TNF-\u03b1 levels were higher in ES (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Mood disturbances were also greater, with lower vigor (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) and higher TMD (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Sarcopenic older adults exhibit muscle impairments, sleep disturbances, and increased inflammation, which may accelerate sarcopenia progression, making sleep and inflammation important targets for intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11325-026-03795-9","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:22:36Z","timestamp":1788510156000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sleep disturbances, inflammation, and muscle function in older adults with sarcopenia"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-5371","authenticated-orcid":false,"given":"Helton","family":"de S\u00e1 Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3012-1327","authenticated-orcid":false,"given":"Luciano Bernardes","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Forte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Henrique Viana","family":"Mendes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4822-4279","authenticated-orcid":false,"given":"Guilherme Pereira","family":"Saborosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Eduardo Eust\u00f3rgio Pinheiro C","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leoncio Lopes","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronaldo Vagner","family":"Thomatieli-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Moreira","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Tufik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0947-5312","authenticated-orcid":false,"given":"V\u00e2nia","family":"D\u2019Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"3795_CR1","doi-asserted-by":"publisher","unstructured":"Sayer AA, Cruz-Jentoft A (2022) Sarcopenia definition, diagnosis and treatment: consensus is growing. 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