{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:40:31Z","timestamp":1792456831108,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sleep Breath"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s11325-026-03826-5","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:21:42Z","timestamp":1791271302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials"],"prefix":"10.1007","volume":"30","author":[{"given":"Giulia","family":"Carvalhal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Meritxell Roca","family":"Mora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo Alberto","family":"Peralta-Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laith","family":"Ayasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian","family":"Barrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavita","family":"Advani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0260-0344","authenticated-orcid":false,"given":"Jafar","family":"Aljazeeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"issue":"1","key":"3826_CR1","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1152\/physrev.00043.2008","volume":"90","author":"JA Dempsey","year":"2010","unstructured":"Dempsey JA, Veasey SC, Morgan BJ, O\u2019Donnell CP (2010) Pathophysiology of Sleep Apnea. Physiol Rev 90(1):47\u2013112","journal-title":"Physiol Rev"},{"issue":"03","key":"3826_CR2","doi-asserted-by":"publisher","first-page":"479","DOI":"10.5664\/jcsm.6506","volume":"13","author":"VK Kapur","year":"2017","unstructured":"Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, Harrod CG (2017) Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med 13(03):479\u2013504","journal-title":"J Clin Sleep Med"},{"issue":"8","key":"3826_CR3","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","volume":"7","author":"AV Benjafield","year":"2019","unstructured":"Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR, Penzel T, P\u00e9pin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A (2019) Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med 7(8):687\u2013698","journal-title":"Lancet Respir Med"},{"issue":"23","key":"3826_CR4","doi-asserted-by":"publisher","first-page":"3015","DOI":"10.1001\/jama.284.23.3015","volume":"284","author":"PE Peppard","year":"2000","unstructured":"Peppard PE (2000) Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA 284(23):3015","journal-title":"JAMA"},{"issue":"8","key":"3826_CR5","doi-asserted-by":"publisher","first-page":"e1000132","DOI":"10.1371\/journal.pmed.1000132","volume":"6","author":"NM Punjabi","year":"2009","unstructured":"Punjabi NM, Caffo BS, Goodwin JL, Gottlieb DJ, Newman AB, O\u2019Connor GT, Rapoport DM, Redline S, Resnick HE, Robbins JA, Shahar E, Unruh ML, Samet JM (2009) Sleep-disordered breathing and mortality: a prospective cohort study. Patel A, editor. PLoS Med 6(8):e1000132","journal-title":"PLoS Med"},{"issue":"4","key":"3826_CR6","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1161\/CIRCULATIONAHA.109.901801","volume":"122","author":"DJ Gottlieb","year":"2010","unstructured":"Gottlieb DJ, Yenokyan G, Newman AB, O\u2019Connor GT, Punjabi NM, Quan SF, Redline S, Resnick HE, Tong EK, Diener-West M, Shahar E (2010) Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation 122(4):352\u2013360","journal-title":"Circulation"},{"issue":"4","key":"3826_CR7","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1378\/chest.15-0229","volume":"148","author":"G Cadby","year":"2015","unstructured":"Cadby G, McArdle N, Briffa T, Hillman DR, Simpson L, Knuiman M, Hung J (2015) Severity of OSA is an independent predictor of incident atrial fibrillation hospitalization in a large sleep-clinic cohort. Chest 148(4):945\u2013952","journal-title":"Chest"},{"issue":"2","key":"3826_CR8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1164\/rccm.200911-1746OC","volume":"182","author":"S Redline","year":"2010","unstructured":"Redline S, Yenokyan G, Gottlieb DJ, Shahar E, O\u2019Connor GT, Resnick HE, Diener-West M, Sanders MH, Wolf PA, Geraghty EM, Ali T, Lebowitz M, Punjabi NM (2010) Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. Am J Respir Crit Care Med 182(2):269\u2013277","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"3826_CR9","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1111\/obr.12020","volume":"14","author":"G Musso","year":"2013","unstructured":"Musso G, Cassader M, Olivetti C, Rosina F, Carbone G, Gambino R (2013) Association of obstructive sleep apnoea with the presence and severity of non\u2010alcoholic fatty liver disease. A systematic review and meta\u2010analysis. Obes Rev 14(5):417\u2013431","journal-title":"Obes Rev"},{"issue":"12","key":"3826_CR10","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/j.amjmed.2009.04.026","volume":"122","author":"N Botros","year":"2009","unstructured":"Botros N, Concato J, Mohsenin V, Selim B, Doctor K, Yaggi HK (2009) Obstructive sleep apnea as a risk factor for type 2 diabetes. Am J Med 122(12):1122\u20131127","journal-title":"Am J Med"},{"issue":"7","key":"3826_CR11","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.jacc.2013.05.045","volume":"62","author":"LF Drager","year":"2013","unstructured":"Drager LF, Togeiro SM, Polotsky VY, Lorenzi-Filho G (2013) Obstructive sleep apnea. J Am Coll Cardiol 62(7):569\u2013576","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"3826_CR12","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.sleep.2009.10.005","volume":"11","author":"S Tufik","year":"2010","unstructured":"Tufik S, Santos-Silva R, Taddei JA, Bittencourt LRA (2010) Obstructive sleep apnea syndrome in the Sao Paulo epidemiologic sleep study. Sleep Med 11(5):441\u2013446","journal-title":"Sleep Med"},{"issue":"19","key":"3826_CR13","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1056\/NEJM200005113421901","volume":"342","author":"PE Peppard","year":"2000","unstructured":"Peppard PE, Young T, Palta M, Skatrud J (2000) Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342(19):1378\u20131384","journal-title":"N Engl J Med"},{"issue":"3","key":"3826_CR14","doi-asserted-by":"publisher","first-page":"263","DOI":"10.5664\/jcsm.27497","volume":"5","author":"LJ Epstein","year":"2009","unstructured":"Epstein LJ, Kristo D, Strollo PJ, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD, Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5(3):263\u201376","journal-title":"J Clin Sleep Med"},{"issue":"02","key":"3826_CR15","doi-asserted-by":"publisher","first-page":"301","DOI":"10.5664\/jcsm.7638","volume":"15","author":"SP Patil","year":"2019","unstructured":"Patil SP, Ayappa IA, Caples SM, Kimoff RJ, Patel SR, Harrod CG (2019) Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med 15(02):301\u2013334","journal-title":"J Clin Sleep Med"},{"issue":"2","key":"3826_CR16","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1513\/pats.200708-119MG","volume":"5","author":"TE Weaver","year":"2008","unstructured":"Weaver TE, Grunstein RR (2008) Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 5(2):173\u2013178","journal-title":"Proc Am Thorac Soc"},{"issue":"1","key":"3826_CR17","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s40463-016-0156-0","volume":"45","author":"BW Rotenberg","year":"2016","unstructured":"Rotenberg BW, Murariu D, Pang KP (2016) Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol Head Neck Surg 45(1):43","journal-title":"J Otolaryngol Head Neck Surg"},{"issue":"3","key":"3826_CR18","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1136\/thoraxjnl-2014-205361","volume":"70","author":"LF Drager","year":"2015","unstructured":"Drager LF, Brunoni AR, Jenner R, Lorenzi-Filho G, Bensenor IM, Lotufo PA (2015) Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials. Thorax 70(3):258\u2013264","journal-title":"Thorax"},{"issue":"1","key":"3826_CR19","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1411892","volume":"373","author":"X Pi-Sunyer","year":"2015","unstructured":"Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, Lau DCW, Le Roux CW, Violante Ortiz R, Jensen CB, Wilding JPH (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med 373(1):11\u201322","journal-title":"N Engl J Med"},{"issue":"10402","key":"3826_CR20","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/S0140-6736(23)01200-X","volume":"402","author":"WT Garvey","year":"2023","unstructured":"Garvey WT, Frias JP, Jastreboff AM, Le Roux CW, Sattar N, Aizenberg D, Mao H, Zhang S, Ahmad NN, Bunck MC, Benabbad I, Zhang XM, Abalos FH, Manghi FCP, Zaidman CJ, Vico ML, Aizenberg D, Costanzo PR, Serra LP, MacKinnon IJ, Hissa MN, Vidotti MH, Kerr Saraiva JF, Alves BB, Franco DR, Moratto O, Murthy S, Goyal G, Yamasaki Y, Sato N, Inoue S, Asakura T, Shestakova M, Khaykina E, Troshina E, Vorokhobina N, Ametov A, Tu ST, Yang CY, Lee IT, Huang CN, Ou HY, Freeman G, Machineni S, Klein K, Sultan S, Parsa A, Otero-Martinez J, Gonzalez A, Bhargava A, Brian S, Ince C, Plantholt S, Cole J, Lacour A, Vega D, De Souza J, Rohlf JL, St. John RC, Horowitz B, Audish H, Galindo R, Umpiperrez G, Ard J, Curtis B, Garvey WT, Fraser NJ, Mandry J, Mohseni R, Mayfield R, Powell T, Vance C, Ong S, Lewy-Alterbaum AL, Murray A, Al-Karadsheh A, Yacoub T, Roberts K, Fried DL, Rosenstock J, Pulla B, Bode B, Frias J, Klaff L, Brazg R, Van J, Tan A, Briskin T, Rhee M, Chaicha-Brom T, Hartley PA, Nunez L, Cortes-Maisonet G, Soucie G, Hsia S, Jones T (2023) Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet 402(10402):613\u2013626","journal-title":"Lancet"},{"key":"3826_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1431292","volume":"15","author":"QK Liu","year":"2024","unstructured":"Liu QK (2024) Mechanisms of action and therapeutic applications of GLP-1 and dual GIP\/GLP-1 receptor agonists. Front Endocrinol (Lausanne) 15:1431292","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"3826_CR22","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1515\/jbcpp-2024-0193","volume":"36","author":"AA Alluri","year":"2025","unstructured":"Alluri AA, Mohan Kurien M, Pokar NP, Madarapu A, Sadam S, Puvvala N, Seetharaman R (2025) Exploring the therapeutic potential of GLP-1 receptor agonists in the management of obstructive sleep apnea: a comprehensive review. J Basic Clin Physiol Pharmacol 36(1):13\u201325","journal-title":"J Basic Clin Physiol Pharmacol"},{"key":"3826_CR23","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2404881","author":"A Malhotra","year":"2024","unstructured":"Malhotra A, Grunstein RR, Fietze I, Weaver TE, Redline S, Azarbarzin A, Sands SA, Schwab RJ, Dunn JP, Chakladar S, Bunck MC (2024) Tirzepatide for the treatment of obstructive sleep apnea and obesity. N Engl J Med 391(13):1193\u2013205. https:\/\/doi.org\/10.1056\/NEJMoa2404881","journal-title":"N Engl J Med"},{"key":"3826_CR24","first-page":"n71","volume":"372","author":"MJ Page","year":"2020","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hr\u00f3bjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2020) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"3826_CR25","volume-title":"Cochrane handbook for systematic reviews of interventions, Version 6.4","author":"JPT Higgins","year":"2023","unstructured":"Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (2023) Cochrane handbook for systematic reviews of interventions, Version 6.4. Cochrane"},{"key":"3826_CR26","unstructured":"De Almeida GC, Ayasa L, Peralta-Jim\u00e9nez GA, Mora MMR, Barrera V, Advani K, Alizeeri J. GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials [Internet]. [cited 2024 Oct 19]. Report No.: PROSPERO 2024 CRD42024564018. Available from: https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?ID=CRD42024564018"},{"issue":"6","key":"3826_CR27","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1177\/0962280216669183","volume":"27","author":"D Luo","year":"2018","unstructured":"Luo D, Wan X, Liu J, Tong T (2018) Optimally estimating the sample mean from the sample size, median, mid-range, and\/or mid-quartile range. Stat Methods Med Res 27(6):1785\u20131805","journal-title":"Stat Methods Med Res"},{"issue":"1","key":"3826_CR28","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1186\/1471-2288-14-135","volume":"14","author":"X Wan","year":"2014","unstructured":"Wan X, Wang W, Liu J, Tong T (2014) Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range. BMC Med Res Methodol 14(1):135","journal-title":"BMC Med Res Methodol"},{"key":"3826_CR29","unstructured":"Allaire J (2012) RStudio: integrated development environment for R. Boston, ma 770(394):165\u201371"},{"key":"3826_CR30","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, Emberson JR, Hern\u00e1n MA, Hopewell S, Hr\u00f3bjartsson A, Junqueira DR, J\u00fcni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JPT (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898","journal-title":"BMJ"},{"key":"3826_CR31","doi-asserted-by":"crossref","unstructured":"GRADE Working Group (2004) Grading quality of evidence and strength of recommendations. Bmj 328(7454):1490","DOI":"10.1136\/bmj.328.7454.1490"},{"issue":"2","key":"3826_CR32","first-page":"e1230","volume":"18","author":"NR Haddaway","year":"2020","unstructured":"Haddaway NR, Page MJ, Pritchard CC, McGuinness LA (2020) PRISMA2020: an R package and shiny app for producing PRISMA 2020\u2010compliant flow diagrams, with interactivity for optimised digital transparency and open synthesis. Campbell Syst Rev 18(2):e1230","journal-title":"Campbell Syst Rev"},{"issue":"3","key":"3826_CR33","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1513\/AnnalsATS.202309-821OC","volume":"21","author":"C O\u2019Donnell","year":"2024","unstructured":"O\u2019Donnell C, Crilly S, O\u2019Mahony A, O\u2019Riordan B, Traynor M, Gitau R, McDonald K, Ledwidge M, O\u2019Shea D, Murphy DJ, Dodd JD, Ryan S (2024) Continuous positive airway pressure but not GLP1-mediated weight loss improves early cardiovascular disease in obstructive sleep apnea: a randomized proof-of-concept study. Ann Am Thorac Soc 21(3):464\u2013473","journal-title":"Ann Am Thorac Soc"},{"issue":"5","key":"3826_CR34","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1007\/s11325-022-02768-y","volume":"27","author":"W Jiang","year":"2023","unstructured":"Jiang W, Li W, Cheng J, Li W, Cheng F (2023) Efficacy and safety of liraglutide in patients with type 2 diabetes mellitus and severe obstructive sleep apnea. Sleep Breath 27(5):1687\u20131694","journal-title":"Sleep Breath"},{"issue":"7","key":"3826_CR35","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-038856","volume":"10","author":"VS Sprung","year":"2020","unstructured":"Sprung VS, Kemp GJ, Wilding JP, Adams V, Murphy K, Burgess M, Emegbo S, Thomas M, Needham AJ, Weimken A, Schwab RJ, Manuel A, Craig SE, Cuthbertson DJ (2020) Randomised, controlled multicentre trial of 26 weeks subcutaneous liraglutide (a glucagon-like peptide-1 receptor agonist), with or without continuous positive airway pressure (CPAP), in patients with type 2 diabetes mellitus (T2DM) and obstructive sleep apnoea (OSA) (ROMANCE): study protocol assessing the effects of weight loss on the apnea-hypnoea index (AHI). BMJ Open 10(7):e038856","journal-title":"BMJ Open"},{"issue":"8","key":"3826_CR36","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1038\/ijo.2016.52","volume":"40","author":"A Blackman","year":"2016","unstructured":"on behalf of the SCALE study group, Blackman A, Foster GD, Zammit G, Rosenberg R, Aronne L, Wadden T, Claudius B, Jensen CB, Mignot E (2016) Effect of liraglutide 3.0 mg in individuals with obesity and moderate or severe obstructive sleep apnea: the SCALE Sleep Apnea randomized clinical trial. Int J Obes 40(8):1310\u20139","journal-title":"Int J Obes"},{"key":"3826_CR37","unstructured":"University of Liverpool. A randomized, controlled multi-centre trial of 26 weeks of subcutaneous Liraglutide (a GLP1 receptor agonist), with or without continuous positive airway pressure (CPAP), in patients with Type 2 Diabetes Mellitus (T2DM) and Obstructive Sleep Apnoea (OSA). In [cited 2020 Oct 25]. (EUDRACT identifier: 2014\u2013000988\u201341). Available from: https:\/\/www.clinicaltrialsregister.eu\/ctr-search\/trial\/2014-000988-41\/results"},{"issue":"1","key":"3826_CR38","first-page":"11","volume":"12","author":"KDR Le","year":"2024","unstructured":"Le KDR, Le K, Foo F (2024) The impact of glucagon-like peptide 1 receptor agonists on obstructive sleep apnoea: a scoping review. Pharmacy (Basel) 12(1):11","journal-title":"Pharmacy (Basel)"},{"key":"3826_CR39","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.5114\/amsad\/161170","volume":"8","author":"GS Papaetis","year":"2023","unstructured":"Papaetis GS (2023) GLP-1 receptor agonists, SGLT-2 inhibitors, and obstructive sleep apnoea: can new allies face an old enemy? Arch Med Sci Atheroscler Dis 8:e19-34","journal-title":"Arch Med Sci Atheroscler Dis"},{"issue":"6","key":"3826_CR40","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.133429","volume":"5","author":"S Gabery","year":"2020","unstructured":"Gabery S, Salinas CG, Paulsen SJ, Ahnfelt-R\u00f8nne J, Alanentalo T, Baquero AF, Buckley ST, Farkas E, Fekete C, Frederiksen KS, Helms HCC, Jeppesen JF, John LM, Pyke C, N\u00f8hr J, Lu TT, Polex-Wolf J, Prevot V, Raun K, Simonsen L, Sun G, Szilv\u00e1sy-Szab\u00f3 A, Willenbrock H, Secher A, Knudsen LB, Hogendorf WFJ (2020) Semaglutide lowers body weight in rodents via distributed neural pathways. JCI Insight 5(6):e133429","journal-title":"JCI Insight"},{"issue":"8","key":"3826_CR41","volume":"12","author":"R Sultana","year":"2022","unstructured":"Sultana R, Sissoho F, Kaushik VP, Raji MA (2022) The case for early use of glucagon-like peptide-1 receptor agonists in obstructive sleep apnea patients with comorbid diabetes and metabolic syndrome. Life (Basel) 12(8):1222","journal-title":"Life (Basel)"},{"issue":"10","key":"3826_CR42","first-page":"821","volume":"331","author":"E Harris","year":"2024","unstructured":"Harris E (2024) Tirzepatide lowered blood pressure in people with obesity. JAMA 331(10):821","journal-title":"JAMA"},{"issue":"5","key":"3826_CR43","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1161\/01.HYP.0000094221.86888.AE","volume":"42","author":"JE Neter","year":"2003","unstructured":"Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM (2003) Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension 42(5):878\u2013884","journal-title":"Hypertension"},{"issue":"2021","key":"3826_CR44","first-page":"6518221","volume":"30","author":"H Yaribeygi","year":"2021","unstructured":"Yaribeygi H, Farrokhi FR, Abdalla MA, Sathyapalan T, Banach M, Jamialahmadi T, Sahebkar A (2021) The effects of glucagon-like peptide-1 receptor agonists and dipeptydilpeptidase-4 inhibitors on blood pressure and cardiovascular complications in diabetes. J Diabetes Res 30(2021):6518221","journal-title":"J Diabetes Res"}],"container-title":["Sleep and Breathing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-026-03826-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11325-026-03826-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11325-026-03826-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:02:57Z","timestamp":1792454577000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11325-026-03826-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["3826"],"URL":"https:\/\/doi.org\/10.1007\/s11325-026-03826-5","relation":{},"ISSN":["1520-9512","1522-1709"],"issn-type":[{"value":"1520-9512","type":"print"},{"value":"1522-1709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"12 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This systematic review and meta-analysis did not require ethical approval as it utilized publicly available data from previously published studies.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Nothing to declare.","order":2,"name":"Ethics","label":"Disclosure of potential conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers\u2019 bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The abstract of preliminary results of this study was presented as a poster presentation at the 2025 International Conference and Annual Meeting of The American Thoracic Society (ATS 2025) in San Francisco, May 2025.","order":4,"name":"Ethics","label":"Conference presentation","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was registered in the PROSPERO database (registration number: CRD42024564018).","order":5,"name":"Ethics","label":"Prospective registration","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"279"}}