{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:03:14Z","timestamp":1791302594567,"version":"4.1.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"15","license":[{"start":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T00:00:00Z","timestamp":1461110400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"the National Science Foundation of China","award":["No. 21267019"],"award-info":[{"award-number":["No. 21267019"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s11356-016-6688-z","type":"journal-article","created":{"date-parts":[[2016,4,19]],"date-time":"2016-04-19T20:59:38Z","timestamp":1461099578000},"page":"15111-15121","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Exploring the correlations between antibiotics and antibiotic resistance genes in the wastewater treatment plants of hospitals in Xinjiang, China"],"prefix":"10.1007","volume":"23","author":[{"given":"Chao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genlin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanbing","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,20]]},"reference":[{"key":"6688_CR1","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/j.1472-765X.2008.02523.x","volume":"48","author":"OO Adelowo","year":"2009","unstructured":"Adelowo OO, Fagade OE (2009) The tetracycline resistance gene tet39 is present in both Gram-negative and Gram-positive bacteria from a polluted river, Southwestern Nigeria. Lett Appl Microbiol 48:167\u2013172. doi: 10.1111\/j.1472-765X.2008.02523.x","journal-title":"Lett Appl Microbiol"},{"key":"6688_CR2","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1111\/j.1365-2672.2007.03445.x","volume":"103","author":"OL Akinbowale","year":"2007","unstructured":"Akinbowale OL, Peng H, Barton MD (2007) Diversity of tetracycline resistance genes in bacteria from aquaculture sources in Australia. J Appl Microbiol 103:2016\u20132025. doi: 10.1111\/j.1365-2672.2007.03445.x","journal-title":"J Appl Microbiol"},{"issue":"6","key":"6688_CR3","doi-asserted-by":"publisher","first-page":"5285","DOI":"10.1007\/s10661-012-2945-x","volume":"185","author":"Y Aktan","year":"2013","unstructured":"Aktan Y, Tan S, Icgen B (2013) Characterization of lead-resistant river isolate Enterococcus faecalis and assessment of its multiple metal and antibiotic resistance. Environ Monit Assess 185(6):5285\u20135293. doi: 10.1007\/s10661-012-2945-x","journal-title":"Environ Monit Assess"},{"key":"6688_CR4","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1128\/AEM.67.1.22-32.2001","volume":"67","author":"RI Aminov","year":"2001","unstructured":"Aminov RI, Garrigues JN, Mackie RI (2001) Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins. Appl Environ Microbiol 67:22\u201332. doi: 10.1128\/AEM.67.1.22-32.2001","journal-title":"Appl Environ Microbiol"},{"key":"6688_CR5","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.scitotenv.2013.03.071","volume":"456\u2013457","author":"H Belinda","year":"2013","unstructured":"Belinda H, Elisabet M, Meritxell G, Pilar L, Marcelo P, Joan A, Dami\u00e0 B, Jose LB, Sara RM, Rafael M (2013) Exploring the links between antibiotic occurrence, antibiotic resistance, and bacterial communities in water supply reservoirs. Sci Total Environ 456\u2013457:161\u2013170. doi: 10.1016\/j.scitotenv.2013.03.071","journal-title":"Sci Total Environ"},{"key":"6688_CR6","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/etc.2784","volume":"32","author":"B Berglund","year":"2015","unstructured":"Berglund B, Fick J, Lindgren PE (2015) Urban wastewater effluent increases antibiotic resistance gene concentrations in a receiving northern European river. Environ Toxicol Chem 32:192\u2013196. doi: 10.1002\/etc.2784","journal-title":"Environ Toxicol Chem"},{"issue":"3","key":"6688_CR7","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1007\/s00248-008-9431-6","volume":"57","author":"MG Brown","year":"2009","unstructured":"Brown MG, Balkwill DL (2009) Antibiotic resistance in bacteria isolated from the deep terrestrial subsurface. Microb Ecol 57(3):484\u201393. doi: 10.1007\/s00248-008-9431-6","journal-title":"Microb Ecol"},{"key":"6688_CR8","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1093\/jac\/dkm204","volume":"60","author":"V Cattoir","year":"2007","unstructured":"Cattoir V, Poirel L, Rotimi V, Soussy CJ, Nordmann P (2007) Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother 60:394\u2013397. doi: 10.1093\/jac\/dkm204","journal-title":"J Antimicrob Chemother"},{"key":"6688_CR9","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.jhazmat.2014.06.010","volume":"282","author":"B Chen","year":"2015","unstructured":"Chen B, Liang X, Nie X, Huang X, Zou S, Li X (2015) The role of class I integrons in the dissemination of sulfonamide resistance genes in the Pearl River and Pearl River Estuary, South China. J Hazard Mater 282:61\u201367. doi: 10.1016\/j.jhazmat.2014.06.010","journal-title":"J Hazard Mater"},{"key":"6688_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.envint.2013.08.023","volume":"61C","author":"W Cheng","year":"2013","unstructured":"Cheng W, Chen H, Su C, Yan S (2013) Abundance and persistence of antibiotic resistance genes in livestock farms: a comprehensive investigation in eastern China. Environ Int 61C:1\u20137. doi: 10.1016\/j.envint.2013.08.023","journal-title":"Environ Int"},{"key":"6688_CR11","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1111\/j.1469-0691.2009.03010.x","volume":"16","author":"S Dahmen","year":"2010","unstructured":"Dahmen S, Poirel L, Mansour W, Bouall\u00e8gue O, Nordmann P (2010) Prevalence of plasmid-mediated quinolone resistance determinants in Enterobacteriaceae from Tunisia. Clin Microbiol Infect 16:1019\u20131023. doi: 10.1111\/j.1469-0691.2009.03010.x","journal-title":"Clin Microbiol Infect"},{"issue":"4","key":"6688_CR12","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s10646-006-0068-2","volume":"15","author":"MJ Souza De","year":"2006","unstructured":"De Souza MJ, Nair S, Loka Bharathi PA, Chan DD (2006) Metal and antibiotic-resistance in psychrotrophic bacteria from Antarctic Marine waters. Ecotoxicology 15(4):379\u2013384","journal-title":"Ecotoxicology"},{"key":"6688_CR13","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.scitotenv.2012.10.026","volume":"442","author":"N Dorival-Garc\u00eda","year":"2013","unstructured":"Dorival-Garc\u00eda N, Zafra-G\u00f3mez A, Naval\u00f3n A, Gonz\u00e1lez J, V\u00edlchez JL (2013) Removal of quinolone antibiotics from wastewaters by sorption and biological degradation in laboratory-scale membrane bioreactors. Sci Total Environ 442:317\u2013328. doi: 10.1016\/j.scitotenv.2012.10.026","journal-title":"Sci Total Environ"},{"key":"6688_CR14","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.1016\/j.watres.2012.02.004","volume":"46","author":"P Gao","year":"2012","unstructured":"Gao P, Mao D, Luo Y, Wang L, Xu B, Xu L (2012) Occurrence of sulfonamide and tetracycline resistant bacteria and resistance genes in aquaculture environment. Water Res 46:2355\u20132364. doi: 10.1016\/j.watres.2012.02.004","journal-title":"Water Res"},{"key":"6688_CR15","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1128\/AAC.45.3.723-726.2001","volume":"45","author":"C Goldstein","year":"2001","unstructured":"Goldstein C, Lee MD, Sanchez S, Hudson C, Phillips B, Register B, Grady M, Liebert C, Summers AO, White DG, Maurer JJ (2001) Incidence of class 1 and 2 integrases in clinical and commensal bacteria from livestock, companion animals, and exotics. Antimicrob Agents Chemother 45:723\u2013726. doi: 10.1128\/AAC.45.3.723-726.2001","journal-title":"Antimicrob Agents Chemother"},{"key":"6688_CR16","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.diagmicrobio.2011.01.004","volume":"70","author":"T Guillard","year":"2011","unstructured":"Guillard T, Moret H, Brasme L, Carlier A, Vernet-Garnier V, Cambau E, de Champs C (2011) Rapid detection of qnr and qepA plasmid-mediated quinolone resistance genes using real-time PCR. Diagn Microbiol Infect Dis 70:253\u2013259. doi: 10.1016\/j.diagmicrobio.2011.01.004","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"9","key":"6688_CR17","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1089\/fpd.2010.0805","volume":"8","author":"SA Hassan","year":"2011","unstructured":"Hassan SA, Altalhi AD, Gherbawy YA, EI-Deeb BA (2011) Bacterial load of fresh vegetables and their resistance to the currently used antibiotics in Saudi Arabia. Foodborne Pathog Dis 8(9):1011\u20131018. doi: 10.1089\/fpd.2010.0805","journal-title":"Foodborne Pathog Dis"},{"key":"6688_CR18","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.psep.2014.04.004","volume":"93","author":"MH Huang","year":"2015","unstructured":"Huang MH, Zhang W, Liu C, Hu HY (2015) Fate of trace tetracycline with resistant bacteria and resistance genes in an improved AAO wastewater treatment plant. Process Saf Environ Prot 93:68\u201374. doi: 10.1016\/j.psep.2014.04.004","journal-title":"Process Saf Environ Prot"},{"key":"6688_CR19","doi-asserted-by":"publisher","first-page":"9075","DOI":"10.1007\/s11356-013-1924-2","volume":"20","author":"H Jiang","year":"2013","unstructured":"Jiang H, Zhang D, Xiao S, Geng C, Zhang X (2013a) Occurrence and sources of antibiotics and their metabolites in river water, WWTPs, and swine wastewater in Jiulongjiang River basin, south China. Environ Sci Pollut Res 20:9075\u20139083. doi: 10.1007\/s11356-013-1924-2","journal-title":"Environ Sci Pollut Res"},{"key":"6688_CR20","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.scitotenv.2013.04.038","volume":"458\u2013460","author":"L Jiang","year":"2013","unstructured":"Jiang L, Hu X, Xu T, Zhang H, Sheng D, Yin D (2013b) Prevalence of antibiotic resistance genes and their relationship with antibiotics in the Huangpu River and the drinking water sources, Shanghai, China. Sci Total Environ 458\u2013460:267\u2013272. doi: 10.1016\/j.scitotenv.2013.04.038","journal-title":"Sci Total Environ"},{"key":"6688_CR21","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.scitotenv.2005.06.030","volume":"361","author":"KG Karthikeyan","year":"2006","unstructured":"Karthikeyan KG, Meyer MT (2006) Occurrence of antibiotics in wastewater treatment facilities in Wisconsin, USA. Sci Total Environ 361:196\u2013207. doi: 10.1016\/j.scitotenv.2005.06.030","journal-title":"Sci Total Environ"},{"issue":"1","key":"6688_CR22","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.femsle.2004.06.026","volume":"237","author":"SR Kim","year":"2004","unstructured":"Kim SR, Nonaka L, Suzuki S (2004) Occurrence of tetracycline resistance genes tet(M) and tet(S) in bacteria from marine aquaculture sites. FEMS Microbiol Lett 237(1):147\u2013156. doi: 10.1016\/j.femsle.2004.06.026","journal-title":"FEMS Microbiol Lett"},{"key":"6688_CR23","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1289\/ehp.1104776","volume":"120","author":"J Li","year":"2012","unstructured":"Li J, Wang T, Shao B, Shen J, Wang S, Wu Y (2012) Plasmid-mediated quinolone resistance genes and antibiotic residues in wastewater and soil adjacent to swine feedlots: potential transfer to agricultural lands. Environ Health Perspect 120:1144\u20131149. doi: 10.1289\/ehp.1104776","journal-title":"Environ Health Perspect"},{"key":"6688_CR24","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.chemosphere.2013.01.040","volume":"92","author":"W Li","year":"2013","unstructured":"Li W, Shi Y, Gao L, Liu J, Cai Y (2013) Occurrence and removal of antibiotics in a municipal wastewater reclamation plant in Beijing, China. Chemosphere 92:435\u2013444. doi: 10.1016\/j.chemosphere.2013.01.040","journal-title":"Chemosphere"},{"issue":"14","key":"6688_CR25","doi-asserted-by":"publisher","first-page":"7551","DOI":"10.1021\/es301145m","volume":"46","author":"M Liu","year":"2012","unstructured":"Liu M, Zhang Y, Yang M, Tian Z, Ren L, Zhang S (2012) Abundance and distribution of tetracycline resistance genes and mobile elements in an oxytetracycline production wastewater treatment system. Environ Sci Technol 46(14):7551\u20137557. doi: 10.1021\/es301145m","journal-title":"Environ Sci Technol"},{"key":"6688_CR26","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.jhazmat.2014.06.015","volume":"278","author":"L Liu","year":"2014","unstructured":"Liu L, Liu YH, Wang Z, Liu CX, Huang X, Zhu GF (2014) Behavior of tetracycline and sulfamethazine with corresponding resistance genes from swine wastewater in pilot-scale constructed wetlands. J Hazard Mater 278:304\u2013310. doi: 10.1016\/j.jhazmat.2014.06.015","journal-title":"J Hazard Mater"},{"key":"6688_CR27","doi-asserted-by":"publisher","first-page":"7720","DOI":"10.1021\/es100233w","volume":"44","author":"Y Luo","year":"2010","unstructured":"Luo Y, Mao D, Rysz M, Zhou Q, Zhang H, Xu L, J J Alvarez P (2010) Trends in antibiotic resistance genes occurrence in the Haihe River, China. Environ Sci Technol 44:7720\u20137225. doi: 10.1021\/es100233w","journal-title":"Environ Sci Technol"},{"key":"6688_CR28","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1021\/es104009s","volume":"45","author":"Y Luo","year":"2011","unstructured":"Luo Y, Xu L, Rysz M, Wang Y, Zhang H, Alvarez PJ (2011) Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environ Sci Technol 45:1827\u20131833. doi: 10.1021\/es104009s","journal-title":"Environ Sci Technol"},{"key":"6688_CR29","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1086\/432056","volume":"41","author":"C MacDougall","year":"2005","unstructured":"MacDougall C, Powell JP, Johnson CK, Edmond MB, Polk RE (2005) Hospital and community fluoroquinolone use and resistance in Staphylococcus aureus and Escherichia coli in 17 US hospitals. Clin Infect Dis 41:435\u2013440. doi: 10.1086\/432056","journal-title":"Clin Infect Dis"},{"key":"6688_CR30","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1038\/nrmicro1462","volume":"4","author":"D Mazel","year":"2006","unstructured":"Mazel D (2006) Integrons: agents of bacterial evolution. Nat Rev Microbiol 4:608\u2013620. doi: 10.1038\/nrmicro1462","journal-title":"Nat Rev Microbiol"},{"key":"6688_CR31","doi-asserted-by":"publisher","first-page":"6102","DOI":"10.1021\/es9038165","volume":"44","author":"CW McKinney","year":"2010","unstructured":"McKinney CW, Loftin KA, Meyer MT, Davis JG, Pruden A (2010) tet and sul antibiotic resistance genes in livestock lagoons of various operation type, configuration, and antibiotic occurrence. Environ Sci Technol 44:6102\u20136109. doi: 10.1021\/es9038165","journal-title":"Environ Sci Technol"},{"issue":"1","key":"6688_CR32","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/AEM.70.1.202-213.2004","volume":"70","author":"VI Miteva","year":"2004","unstructured":"Miteva VI, Sheridan PP, Brenchley JE (2004) Phylogenetic and physiological diversity of microorganisms isolated from a deep Greenland glacier ice core. Appl Environ Microbiol 70(1):202\u2013213","journal-title":"Appl Environ Microbiol"},{"key":"6688_CR33","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.scitotenv.2013.05.052","volume":"461-462C","author":"H N\u00f5lvak","year":"2013","unstructured":"N\u00f5lvak H, Truu M, Tiirik K, Oopkaup K, Sildvee T, Kaasik A, Mander \u00dc, Truu J (2013) Dynamics of antibiotic resistance genes and their relationships with system treatment efficiency in a horizontal subsurface flow constructed wetland. Sci Total Environ 461-462C:636\u2013644. doi: 10.1016\/j.scitotenv.2013.05.052","journal-title":"Sci Total Environ"},{"key":"6688_CR34","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1016\/j.watres.2006.04.017","volume":"40","author":"R Pei","year":"2006","unstructured":"Pei R, Kim SC, Carlson KH, Pruden A (2006) Effect of river landscape on the sediment concentrations of antibiotics and corresponding antibiotic resistance genes (ARG). Water Res 40:2427\u20132435. doi: 10.1016\/j.watres.2006.04.017","journal-title":"Water Res"},{"key":"6688_CR35","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.biortech.2013.12.007","volume":"153","author":"JA Resende","year":"2014","unstructured":"Resende JA, Silva VL, de Oliveira TL, de Oliveira FS, da Costa CJ, Otenio MH, Diniz CG (2014) Prevalence and persistence of potentially pathogenic and antibiotic resistant bacteria during anaerobic digestion treatment of cattle manure. Bioresour Technol 153:284\u201391. doi: 10.1016\/j.biortech.2013.12.007","journal-title":"Bioresour Technol"},{"key":"6688_CR36","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S1473-3099(06)70599-0","volume":"6","author":"A Robicsek","year":"2006","unstructured":"Robicsek A, Jacoby GA, Hooper DC (2006) The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis 6:629\u2013640. doi: 10.1016\/S1473-3099(06)70599-0","journal-title":"Lancet Infect Dis"},{"key":"6688_CR37","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.watres.2014.11.021","volume":"69","author":"S Rodriguez-Mozaz","year":"2015","unstructured":"Rodriguez-Mozaz S, Chamorro S, Marti E, Huerta B, Gros M, S\u00e0nchez-Melsi\u00f3 A, Borrego CM, Barcel\u00f3 D, Balc\u00e1zar JL (2015) Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river. Water Res 69:234\u2013242. doi: 10.1016\/j.watres.2014.11.021","journal-title":"Water Res"},{"issue":"3","key":"6688_CR38","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1111\/j.1462-2920.2009.02100.x","volume":"12","author":"R Ruimy","year":"2010","unstructured":"Ruimy R, Brisabois A, Bernede C, Skurnk D, Barnat S, Arlet G, Momcilovic S, Elbaz S, Moury F, Vibet MA, Courvalin P, Guillemot D, Andremont A (2010) Organic and conventional fruits and vegetables contain equivalent counts of Gram-negative bacteria expressing resistance to antibacterial agents. Environ Microbiol 12(3):608\u2013615. doi: 10.1111\/j.1462-2920.2009.02100.x","journal-title":"Environ Microbiol"},{"key":"6688_CR39","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.chemosphere.2006.03.026","volume":"65","author":"AK Sarmah","year":"2006","unstructured":"Sarmah AK, Meyer MT, Boxall AB (2006) A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 65:725\u2013759. doi: 10.1016\/j.chemosphere.2006.03.026","journal-title":"Chemosphere"},{"key":"6688_CR40","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1128\/AEM.71.3.1394-1404.2005","volume":"71","author":"RS Sayah","year":"2005","unstructured":"Sayah RS, Kaneene JB, Johnson Y, Miller R (2005) Patterns of antimicrobial resistance observed in Escherichia coli isolates obtained from domestic-and wild-animal fecal samples, human septage, and surface water. Appl Environ Microbiol 71:1394\u20131404. doi: 10.1128\/AEM.71.3.1394-1404.2005","journal-title":"Appl Environ Microbiol"},{"key":"6688_CR41","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.envpol.2012.05.007","volume":"169","author":"HC Su","year":"2012","unstructured":"Su HC, Ying GG, Tao R, Zhang RQ, Zhao JL, Liu YS (2012) Class 1 and 2 integrons, sul resistance genes and antibiotic resistance in Escherichia coli isolated from Dongjiang River, South China. Environ Pollut 169:42\u201349. doi: 10.1016\/j.envpol.2012.05.007","journal-title":"Environ Pollut"},{"key":"6688_CR42","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.micpath.2015.09.001","volume":"89","author":"L Tahrani","year":"2015","unstructured":"Tahrani L, Soufi L, Mehri I, Najjari A, Hassan A, Van Loco J, Reyns T, Cherif A, Mansour HB (2015) Isolation and characterization of antibiotic-resistant bacteria from pharmaceutical industrial wastewaters. Microb Pathog 89:54\u201361. doi: 10.1016\/j.micpath.2015.09.001","journal-title":"Microb Pathog"},{"key":"6688_CR43","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.scitotenv.2014.07.024","volume":"496","author":"CW Tao","year":"2014","unstructured":"Tao CW, Hsu BM, Ji WT, Hsu TK, Kao PM, Hsu CP, Shen SM, Shen TY, Wan TJ, Huang YL (2014) Evaluation of five antibiotic resistance genes in wastewater treatment systems of swine farms by real-time PCR. Sci Total Environ 496:116\u2013121. doi: 10.1016\/j.scitotenv.2014.07.024","journal-title":"Sci Total Environ"},{"issue":"42","key":"6688_CR44","doi-asserted-by":"publisher","first-page":"15202","DOI":"10.1073\/pnas.1409836111","volume":"111","author":"N Udikovic-KoLic","year":"2014","unstructured":"Udikovic-KoLic N, Wichmann F, Broderick NA, Handelsman J (2014) Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization. Proc Natl Acad Sci U S A 111(42):15202\u20137. doi: 10.1073\/pnas.1409836111","journal-title":"Proc Natl Acad Sci U S A"},{"key":"6688_CR45","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1080\/10934520902719779","volume":"44","author":"C Wu","year":"2009","unstructured":"Wu C, Spongberg AL, Witter JD (2009) Sorption and biodegradation of selected antibiotics in biosolids. J Environ Sci Health 44:454\u2013461. doi: 10.1080\/10934520902719779","journal-title":"J Environ Sci Health"},{"key":"6688_CR46","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1016\/j.chemosphere.2014.02.040","volume":"119","author":"J Xu","year":"2015","unstructured":"Xu J, Xu Y, Wang H, Guo C, Qiu H, He Y, Zhang Y, Li X, Meng W (2015) Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river. Chemosphere 119:1379\u20131385. doi: 10.1016\/j.chemosphere.2014.02.040","journal-title":"Chemosphere"},{"key":"6688_CR47","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/j.watres.2011.12.035","volume":"46","author":"SF Yang","year":"2012","unstructured":"Yang SF, Lin CF, Wu CJ, Ng KK, Lin AY, Hong PK (2012) Fate of sulfonamide antibiotics in contact with activated sludge\u2014sorption and biodegradation. Water Res 46:1301\u20131308. doi: 10.1016\/j.watres.2011.12.035","journal-title":"Water Res"},{"issue":"7","key":"6688_CR48","doi-asserted-by":"publisher","first-page":"2598","DOI":"10.1021\/es103672x","volume":"45","author":"XX Zhang","year":"2011","unstructured":"Zhang XX, Zhang T (2011) Occurrence, abundance, and diversity of tetracycline resistance genes in 15 sewage treatment plants across China and other global locations. Environ Sci Technol 45(7):2598\u20132604. doi: 10.1021\/es103672x","journal-title":"Environ Sci Technol"},{"key":"6688_CR49","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1007\/s00253-009-1886-y","volume":"182","author":"XX Zhang","year":"2009","unstructured":"Zhang XX, Zhang T, Zhang M, Fang HH, Cheng SP (2009) Characterization and quantification of class 1 integrons and associated gene cassettes in sewage treatment plants. Appl Microbiol Biotechnol 182:1169\u20131177. doi: 10.1007\/s00253-009-1886-y","journal-title":"Appl Microbiol Biotechnol"},{"issue":"5","key":"6688_CR50","doi-asserted-by":"publisher","first-page":"925","DOI":"10.2166\/wst.2014.321","volume":"70","author":"T Zhou","year":"2014","unstructured":"Zhou T, Lu J, Tong Y, Li S, Wang X (2014) Distribution of antibiotic resistance genes in Bosten Lake, Xinjiang, China. Water Sci Technol 70(5):925\u2013931. doi: 10.2166\/wst.2014.321","journal-title":"Water Sci Technol"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-016-6688-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11356-016-6688-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-016-6688-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T10:16:08Z","timestamp":1559384168000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11356-016-6688-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,20]]},"references-count":50,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["6688"],"URL":"https:\/\/doi.org\/10.1007\/s11356-016-6688-z","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,20]]}}}