{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:55:22Z","timestamp":1790740522363,"version":"4.1.0"},"reference-count":79,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T00:00:00Z","timestamp":1483660800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Ministry of Research and education. Tunisia","award":["UR11ES70"],"award-info":[{"award-number":["UR11ES70"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s11356-016-8323-4","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T23:07:38Z","timestamp":1483657658000},"page":"5841-5856","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Pyrethroid insecticide lambda-cyhalothrin and its metabolites induce liver injury through the activation of oxidative stress and proinflammatory gene expression in rats following acute and subchronic exposure"],"prefix":"10.1007","volume":"24","author":[{"given":"Bakhta","family":"Aouey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Derbali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassine","family":"Chtourou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mich\u00e8le","family":"Bouchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelmajid","family":"Khabir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamadi","family":"Fetoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"8323_CR1","first-page":"141","volume":"10","author":"M Abdollahi","year":"2004","unstructured":"Abdollahi M, Ranjbar A, Shadnia S, Nikfar S, Rezaie A (2004) Pesticides and oxidative stress: a review. Med Sci Monit 10:141\u2013147","journal-title":"Med Sci Monit"},{"key":"8323_CR2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","volume":"105","author":"H Aebi","year":"1984","unstructured":"Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121\u2013126","journal-title":"Methods Enzymol"},{"key":"8323_CR3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.toxlet.2006.01.014","volume":"165","author":"A Anad\u00f3n","year":"2006","unstructured":"Anad\u00f3n A, Mart\u00ednez M, Mart\u00ednez MA, Diaz MJ, Mart\u00ednez-Larra\u00f1aga MR (2006) Toxicokinetics of lambda-cyhalothrin in rats. Toxicol Lett 165:47\u201356","journal-title":"Toxicol Lett"},{"key":"8323_CR4","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.toxlet.2013.04.015","volume":"220","author":"A Anadon","year":"2013","unstructured":"Anadon A, Martinez MA, Martinez M, Castellano V, Ares I, Romero A, Fernadez R, Martinez-Larranaga MR (2013) Differential induction of cytochrome P450 isoforms and peroxisomal proliferation by cyfluthrin in rats. Toxicol Lett 220:135\u2013142","journal-title":"Toxicol Lett"},{"key":"8323_CR5","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/humrep\/15.2.366","volume":"15","author":"AG Andersen","year":"2000","unstructured":"Andersen AG, Jensen TK, Carlsen E, Jorgensen N, Andersson AM, Krarup T, Keiding N, Skkaek NE (2000) Fr\u00e9quence \u00e9lev\u00e9e de qualit\u00e9 de sperme inf\u00e9rieure \u00e0 la moyenne chez une population non s\u00e9lectionn\u00e9e d\u2019hommes jeunes. Reproduction Humaine 15:366\u2013372","journal-title":"Reproduction Humaine"},{"key":"8323_CR6","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1600-065X.2008.00624.x","volume":"223","author":"WP Arend","year":"2008","unstructured":"Arend WP, Palmer G, Gabay C (2008) IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223:20\u201338","journal-title":"Immunol Rev"},{"key":"8323_CR7","volume-title":"Toxicological profile for pyrethrins and pyrethroids","author":"ATSDR (Agency for Toxic Substances and Disease Registry)","year":"2003","unstructured":"ATSDR (Agency for Toxic Substances and Disease Registry) (2003) Toxicological profile for pyrethrins and pyrethroids. Department of Health and Human Services, Atlanta"},{"key":"8323_CR8","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1002\/etc.5620190917","volume":"19","author":"JB Belden","year":"2000","unstructured":"Belden JB, Lydy MJ (2000) Impact of atrazine on organophosphate insecticide toxicity. Environ Toxicol Chem 19:2266\u20132274","journal-title":"Environ Toxicol Chem"},{"key":"8323_CR9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0378-4274(00)00277-0","volume":"118","author":"G Belma","year":"2001","unstructured":"Belma G, Aylin G, Filiz H (2001) Cypermethrin-induced oxidative stress in rat brain and liver is prevented by vitamin E or allopurinol. Toxicol Lett 118:139\u2013146","journal-title":"Toxicol Lett"},{"key":"8323_CR10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1191\/096032701682692946","volume":"20","author":"K Ben Rhouma","year":"2001","unstructured":"Ben Rhouma K, Tebourbi O, Krichah RN, Sakly M (2001) Reproductive toxicity of DDT in adult male rats. Hum Exp Toxicol 20:393\u2013397","journal-title":"Hum Exp Toxicol"},{"key":"8323_CR11","first-page":"19","volume":"118","author":"LR Borza","year":"2014","unstructured":"Borza LR (2014) A review on the cause-effect relationship between oxidative stress and toxic proteins in the pathogenesis of neurodegenerative diseases. Rev Med Chir Soc Med Nat Iasi 118:19\u201327","journal-title":"Rev Med Chir Soc Med Nat Iasi"},{"key":"8323_CR12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochemist 72:248","journal-title":"Anal Biochemist"},{"key":"8323_CR13","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0048-9697(96)05276-X","volume":"188","author":"F Bro-Rasmussen","year":"1996","unstructured":"Bro-Rasmussen F (1996) Contamination by persistent chemicals in food chain and human health. Sci Total Environ 188:45\u201360","journal-title":"Sci Total Environ"},{"key":"8323_CR14","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0048-3575(02)00154-2","volume":"73","author":"J Choi","year":"2002","unstructured":"Choi J, Rose RL, Hodgson E (2002) In vitro metabolism of permethrin: the role of human alcohol and aldehyde dehydrogenases. Pestic Biochem Physiol 73:117\u2013128","journal-title":"Pestic Biochem Physiol"},{"key":"8323_CR15","unstructured":"Colborn T, Myers PJ, Dumanoski D (1996) Our stolen future. Penguin Boocks, USA Inc., New York. Consensus d\u2019actualisation SFAR - M\u00e9decine d\u2019Urgence. 18"},{"key":"8323_CR16","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.taap.2005.01.025","volume":"207","author":"C Colosio","year":"2005","unstructured":"Colosio C, Birindelli S, Corsini E, Galli CL, Maroni M (2005) Low level exposure to chemicals and immune system. Toxicol Appl Pharmacol 207:320\u2013328","journal-title":"Toxicol Appl Pharmacol"},{"key":"8323_CR17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1080\/15459620902850907","volume":"6","author":"C Couture","year":"2014","unstructured":"Couture C, Fortin MC, Carrier G, Dumas P, Tremblay C, Bouchard M (2014) Assessment of exposure to pyrethroids and pyrethrins in a rural population of the Mont\u00e9r\u00e9gie area, Quebec, Canada. J Occup Environ Hyg 6:341\u2013352","journal-title":"J Occup Environ Hyg"},{"key":"8323_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.taap.2007.03.002","volume":"221","author":"JA Crow","year":"2007","unstructured":"Crow JA, Borazjani A, Potter PM, Ross MK (2007) Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases. Toxicol Appl Pharmacol 221:1\u201312","journal-title":"Toxicol Appl Pharmacol"},{"key":"8323_CR19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.clim.2008.08.018","volume":"130","author":"O Dienz","year":"2009","unstructured":"Dienz O, Rincon M (2009) The effects of IL-6 on CD4 T cell responses. Clin Immunol 130:27\u201333","journal-title":"Clin Immunol"},{"key":"8323_CR20","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0076-6879(90)86135-I","volume":"86","author":"HH Draper","year":"1990","unstructured":"Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Methods Ezymol 86:421\u2013431","journal-title":"Methods Ezymol"},{"key":"8323_CR21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0892-0362(99)00069-0","volume":"22","author":"AS Driver","year":"2002","unstructured":"Driver AS, Kodavanti PS, Mundy WR (2002) Age related changes in reactive oxygen species production in rat brain homogenates. Neurotoxicol Teratol 22:175\u2013181","journal-title":"Neurotoxicol Teratol"},{"key":"8323_CR22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.pestbp.2009.11.008","volume":"97","author":"V Duzguner","year":"2010","unstructured":"Duzguner V, Erdogan S (2010) Acute oxidant and inflammatory effects of imidacloprid on the mammalian central nervous system and liver in rats. Pest Biochem Physiol 97:13\u201318","journal-title":"Pest Biochem Physiol"},{"key":"8323_CR23","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.tiv.2006.09.019","volume":"21","author":"FM El-Demerdash","year":"2007","unstructured":"El-Demerdash FM (2007) Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicol in Vitro 21:392\u2013397","journal-title":"Toxicol in Vitro"},{"key":"8323_CR24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pestbp.2008.01.006","volume":"91","author":"MEA Elhalwagy","year":"2008","unstructured":"Elhalwagy MEA, Darwish EM, Zaher NS (2008) Prophylactic effect of green tea polyphenols against liver and kidney injury induced by fenitrothion insecticide. Pest Biochem Physiol 91:81\u201389","journal-title":"Pest Biochem Physiol"},{"key":"8323_CR25","doi-asserted-by":"crossref","first-page":"5552","DOI":"10.1039\/c3cs60064e","volume":"42","author":"M Elsabahy","year":"2013","unstructured":"Elsabahy M, Wooley KL (2013) Cytokines as biomarkers of nanoparticle immunotoxicity. Chem Soc Rev 42:5552\u20135576","journal-title":"Chem Soc Rev"},{"key":"8323_CR26","first-page":"92","volume":"6","author":"TA Fedotchevaa","year":"2012","unstructured":"Fedotchevaa TA, Shimanovskiia NL, Kruglovb AG, Teplovab VV, Fedotchevab NI (2012) Role of mitochondrial thiols of different localization in the generation of reactive oxygen species. Memb Cell Biol 6:92\u201399","journal-title":"Memb Cell Biol"},{"key":"8323_CR27","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.nutres.2006.06.016","volume":"26","author":"H Fetoui","year":"2006","unstructured":"Fetoui H, Mahjoubi-Samet A, Jammousi K, Ellouze F, Guermazi F, Zeghal N (2006) Energy restriction in pregnant and lactating rats lowers bone mass of their progeny. Nutr Res 26:421\u2013426","journal-title":"Nutr Res"},{"key":"8323_CR28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.etap.2008.04.002","volume":"26","author":"H Fetoui","year":"2008","unstructured":"Fetoui H, Garoui el M, Makni-Ayadi F, Zeghal N (2008) Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: attenuation by vitamin C. Environ Toxicol Pharmacol 26:225\u2013231","journal-title":"Environ Toxicol Pharmacol"},{"key":"8323_CR29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.etp.2008.08.002","volume":"61","author":"H Fetoui","year":"2009","unstructured":"Fetoui H, Garoui el M, Zeghal N (2009) Lambda-cyhalothrin-induced biochemical and histopathological changes in the liver of rats: ameliorative effect of ascorbic acid. Exp Toxicol Pathol 61:189\u2013196","journal-title":"Exp Toxicol Pathol"},{"key":"8323_CR30","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.etp.2009.08.004","volume":"62","author":"H Fetoui","year":"2010","unstructured":"Fetoui H, Makni M, Garoui el M, Zeghal N (2010) Toxic effects of lambda-cyhalothrin, a synthetic pyrethroid pesticide, on the rat kidney: involvement of oxidative stress and protective role of ascorbic acid. Exp Toxicol Pathol 62:593\u2013599","journal-title":"Exp Toxicol Pathol"},{"key":"8323_CR31","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0076-6879(84)05015-1","volume":"105","author":"L Flohe","year":"1984","unstructured":"Flohe L, Gunzler WA (1984) Assays of glutathione peroxidase. Method Enzymol 105:114\u2013121","journal-title":"Method Enzymol"},{"key":"8323_CR32","first-page":"237","volume-title":"Anticholinesterase pesticides: metabolism, neurotoxicity, and epidemiology","author":"KD Gill","year":"2010","unstructured":"Gill KD, Flora G, Pachauri V, Flora SJS (2010) Neurotoxicity of organophosphates and carbamates. In: Satoh T, Gupta RC (eds) Anticholinesterase pesticides: metabolism, neurotoxicity, and epidemiology. Wiley, Hoboken, pp 237\u2013265"},{"key":"8323_CR33","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","volume":"126","author":"LC Green","year":"1982","unstructured":"Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR (1982) Analysis of nitrate, nitrite, and [15\u00a0N] nitrate in biological fluids. Anal Biochem 126:131\u2013138","journal-title":"Anal Biochem"},{"key":"8323_CR34","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1074\/jbc.272.6.3346","volume":"272","author":"AP Halestrap","year":"1997","unstructured":"Halestrap AP, Woodfield KY, Connern CP (1997) Oxidative stress, thiol reagents and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide carrier. J Biol Chem 272:3346\u20133354","journal-title":"J Biol Chem"},{"key":"8323_CR35","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1383-5742(99)00009-5","volume":"443","author":"B Halliwell","year":"1999","unstructured":"Halliwell B (1999) Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and effects of nutrition. Mutat Res 443:37\u201352","journal-title":"Mutat Res"},{"key":"8323_CR36","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/324073a0","volume":"324","author":"T Hirano","year":"1986","unstructured":"Hirano T, Yasukawa K, Harada H, Taga T, Watanabe Y, Matsuda T, Kashiwamura S, Nakajima K, Koyama K, Iwamatsu A (1986) Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324:73\u201380","journal-title":"Nature"},{"key":"8323_CR37","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/jbt.10080","volume":"17","author":"E Hodgson","year":"2003","unstructured":"Hodgson E (2003) In vitro human phase I metabolism of xenobiotics I: pesticides and related compounds used in agriculture and public health. J Biochem Mol Toxicol 17:201\u2013206","journal-title":"J Biochem Mol Toxicol"},{"key":"8323_CR38","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nature05485","volume":"444","author":"GS Hotamisligil","year":"2006","unstructured":"Hotamisligil GS (2006) Inflammation andmetabolicdisorders. Nature 444:860\u2013867","journal-title":"Nature"},{"key":"8323_CR39","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.etap.2015.11.008","volume":"41","author":"MMA Hussein","year":"2016","unstructured":"Hussein MMA, Ahmed MM (2016) The Th1\/Th2 paradigm in lambda cyhalothrin-induced spleentoxicity: the role of thymoquinone. Environ Toxicol Pharmacol 41:14\u201321","journal-title":"Environ Toxicol Pharmacol"},{"key":"8323_CR40","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1080\/00039896.1991.9937452","volume":"46","author":"SO Igbedioh","year":"1991","unstructured":"Igbedioh SO (1991) Effects of agricultural pesticides on humans, animals and higher plants in developing countries. Arch Environ Health 46:218","journal-title":"Arch Environ Health"},{"key":"8323_CR41","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1034\/j.1600-0773.2001.d01-92.x","volume":"88","author":"MC Jacques-Silva","year":"2001","unstructured":"Jacques-Silva MC, Nogueira CW, Broch LC, Flores EMM, Rocha JBT (2001) Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice. Pharmacol Toxicol 88:119\u2013125","journal-title":"Pharmacol Toxicol"},{"key":"8323_CR42","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0378-4274(98)00399-3","volume":"105","author":"M Kale","year":"1999","unstructured":"Kale M, Rathore N, John S, Bhatnagar D (1999) Lipid peroxidative damage of pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxcicol Lett 105:197\u2013205","journal-title":"Toxcicol Lett"},{"key":"8323_CR43","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.ejcb.2011.10.001","volume":"91","author":"C Liedtke","year":"2012","unstructured":"Liedtke C, Trautwein C (2012) The role of TNF and Fas dependent signaling in animal models of inflammatory liver injury and liver cancer. Eur J Cell Biol 91:582\u2013589","journal-title":"Eur J Cell Biol"},{"key":"8323_CR44","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s00128-013-0961-3","volume":"90","author":"A Loteste","year":"2013","unstructured":"Loteste A, Scagnetti J, Simoniello MF, Campana M, Parma MJ (2013) Hepatic enzymes activity in the fish Prochilodus lineatus (Valenciennes, 1836) after sublethal cypermethrin exposure. Bull Environ Contam Toxicol 90:601\u2013604","journal-title":"Bull Environ Contam Toxicol"},{"key":"8323_CR45","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1600-065X.2007.00579.x","volume":"220","author":"MT Lotze","year":"2007","unstructured":"Lotze MT, Zeh HJ, Rubartelli A, Sparvero LJ, Amoscato AA, Washburn NR, Devera ME, Liang X, Tor M, Billiar T (2007) The grateful dead:damage-associated molecular pattern molecules and reduction\/oxidation reg-ulate immunity. Immunol Rev 220:60\u201381","journal-title":"Immunol Rev"},{"key":"8323_CR46","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.2174\/0929867321666131212144016","volume":"21","author":"L Lu","year":"2014","unstructured":"Lu L, Shi J, Li Q, Peng X, Dong L, Li Y et al (2014) Effects of liver diseases on drug metabolizing enzymes: implications for drug fate alterations and nano-therapeutic openings. Curr Med Chem 21:2522\u20132541","journal-title":"Curr Med Chem"},{"key":"8323_CR47","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pestbp.2008.09.004","volume":"93","author":"SA Mansour","year":"2009","unstructured":"Mansour SA, Mossa AH (2009) Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc. Pest Biochem Physiol 93:34\u201339","journal-title":"Pest Biochem Physiol"},{"key":"8323_CR48","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","volume":"47","author":"S Marklund","year":"1974","unstructured":"Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469\u2013474","journal-title":"Eur J Biochem"},{"key":"8323_CR49","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1002\/etc.689","volume":"30","author":"WT Mehler","year":"2011","unstructured":"Mehler WT, Du J, Lydy MJ, You J (2011) Joint toxicity of a pyrethroid insecticide, cypermethrin, and a heavy metal, lead, to the benthic invertebrate Chironomus dilutus. Environ Toxicol Chem 30:2838\u20132845","journal-title":"Environ Toxicol Chem"},{"key":"8323_CR50","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.mrgentox.2008.09.017","volume":"674","author":"S Mena","year":"2009","unstructured":"Mena S, Ortega A, Jos\u00e9 M, Estrela JM (2009) Oxidative stress in environmental induced carcinogenesis. Mutat Res 674:36\u201344","journal-title":"Mutat Res"},{"key":"8323_CR51","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0005-2736(90)90264-O","volume":"1028","author":"F Michelangeli","year":"1990","unstructured":"Michelangeli F, Robson MJ, East JM, Lee AG (1990) The conformation of pyrethroids bound to lipid bilayers. Biochem Biophys Acta 1028:49\u201357","journal-title":"Biochem Biophys Acta"},{"key":"8323_CR52","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1006\/abbi.2001.2692","volume":"397","author":"J Moskovitz","year":"2002","unstructured":"Moskovitz J, Yim MB, Chock BP (2002) Free radicals and diseases. Arch Biochem Biophys 397:354\u2013359","journal-title":"Arch Biochem Biophys"},{"key":"8323_CR53","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1177\/0748233711425073","volume":"28","author":"S Mostafalou","year":"2012","unstructured":"Mostafalou S, Eghbal MA, Nili-Ahmadabadi A, Baeeri M, Abdollahi M (2012) Biochemical evidence on the potential role of organophosphates in hepatic glucose metabolism toward insulin resistance through inflammatory signaling and free radical pathways. Toxicol Ind Health 28:840\u2013851","journal-title":"Toxicol Ind Health"},{"key":"8323_CR54","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tox.2007.03.016","volume":"235","author":"Y Nakamura","year":"2007","unstructured":"Nakamura Y, Sugihara K, Sone T, Isobe M, Ohta S, Kitamura S (2007) The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolysis products in rats. Toxicology 235:176\u2013184","journal-title":"Toxicology"},{"key":"8323_CR55","doi-asserted-by":"crossref","first-page":"75343","DOI":"10.1371\/journal.pone.0075343","volume":"8","author":"HA Pereira","year":"2013","unstructured":"Pereira HA, Leite Ade L, Charone S, Lobo JG, Cestari TM, Peres-Buzalaf C, Buzalaf MA (2013) Proteomic analysis of liver in rats chronically exposed to fluoride. PLoS One 8:75343","journal-title":"PLoS One"},{"key":"8323_CR56","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1194\/jlr.R600021-JLR200","volume":"48","author":"C Popa","year":"2007","unstructured":"Popa C, Netea MG, van Riel PLCM, van Der Meer JWM, Stalenhoef FH (2007) The role of TNF-\u03b1 in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 48:751\u2013762","journal-title":"J Lipid Res"},{"key":"8323_CR57","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0076-6879(94)33041-7","volume":"233","author":"AZ Reznick","year":"1994","unstructured":"Reznick AZ, Packer L (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Med Enzymol 233:357\u2013363","journal-title":"Med Enzymol"},{"key":"8323_CR58","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.envres.2016.01.023","volume":"146","author":"JL Rodr\u00edguez","year":"2016","unstructured":"Rodr\u00edguez JL, Ares I, Castellano V, Mart\u00ednez M, Mart\u00ednez-Larra\u00f1aga MR, Anad\u00f3n A, Mart\u00ednez MA (2016b) Effects of exposure to pyrethroid cyfluthrin on serotonin and dopamine levels in brain regions of male rats. Environ Res 146:388\u2013394","journal-title":"Environ Res"},{"key":"8323_CR59","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.toxlet.2016.06.2004","volume":"258","author":"JL Rodr\u00edguez","year":"2016","unstructured":"Rodr\u00edguez JL, Ares I, Castellano V, Mart\u00ednez M, Mart\u00ednez Larranaga MR, Anad\u00f3n A, Mart\u00ednez MA (2016a) 5-HT loss in rat brain induced by cyfluthrin. Toxicol Lett 258:288\u2013289","journal-title":"Toxicol Lett"},{"key":"8323_CR60","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.tiv.2012.05.004","volume":"26","author":"A Romero","year":"2012","unstructured":"Romero A, Ramos E, Castellano V, Mart\u00ednez MA, Ares I, Mart\u00ednez M, Mart\u00ednez Larranaga MR, Anad\u00f3n A (2012) Cytotoxicity induced by deltamethrin and its metabolites in SH-SY5Y cells can be differentially prevented by selected antioxidants. Toxicol in Vitro 26:823\u2013830","journal-title":"Toxicol in Vitro"},{"key":"8323_CR61","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.envres.2015.02.008","volume":"138","author":"A Romero","year":"2015","unstructured":"Romero A, Ares I, Ramos E, Castellano V, Martinez M, Martinez-larranaga MR, Anadon A, Martinez MA (2015) Evidence for dose-additive effects of a type II pyrethroid mixture in vitro assessment. Environ Res 138:58\u201366","journal-title":"Environ Res"},{"key":"8323_CR62","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/ki.2012.439","volume":"83","author":"S Ruiz","year":"2013","unstructured":"Ruiz S, Pablo E, Pergola MD, Richard A, Zager MD, Nosratola D, Vaziri MD (2013) Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease. Kidney Int 83:1029\u20131041","journal-title":"Kidney Int"},{"key":"8323_CR63","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","volume":"25","author":"J Sedlak","year":"1968","unstructured":"Sedlak J, Lindsay RH (1968) Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tisue with Ellman\u2019s reagent. Anal Biochem 25:192\u2013205","journal-title":"Anal Biochem"},{"key":"8323_CR64","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.chemosphere.2011.07.024","volume":"85","author":"X Shi","year":"2011","unstructured":"Shi X, Aihua G, Guixiang J, Li Y, Jing D, Jin J, Hu F, Long Y, Xia Y, Lu C, Song L, Wang S, Wang X (2011) Developmental toxicity of cypermethrin in embryolarval stages of zebrafish. Chemosphere 85:1010\u20131016","journal-title":"Chemosphere"},{"key":"8323_CR65","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.ntt.2006.03.005","volume":"28","author":"C Sinha","year":"2006","unstructured":"Sinha C, Seth K, Islam F, Kumar R, Shukla CS, Mathur N, Srivastava Agrawal K (2006) Behavioral and neurochemical effects induced by pyrethroid-based mosquito repellent exposure in rat offsprings during prenatal and early postnatal period. Neurotoxicol Teratol 28:472\u2013481","journal-title":"Neurotoxicol Teratol"},{"key":"8323_CR66","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev.en.34.010189.000453","volume":"34","author":"DM Soderlund","year":"1989","unstructured":"Soderlund DM, Bloomquist JR (1989) Neurotoxic actions of pyrethroid insecticides. Annu Rev Entomol 34:77\u201396","journal-title":"Annu Rev Entomol"},{"key":"8323_CR67","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0300-483X(01)00569-8","volume":"171","author":"DM Soderlund","year":"2002","unstructured":"Soderlund DM, Clark JM, Sheets LP et al (2002) Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment. Toxicol 171:3\u201359","journal-title":"Toxicol"},{"key":"8323_CR68","doi-asserted-by":"crossref","first-page":"190","DOI":"10.4093\/dmj.2012.36.3.190","volume":"36","author":"SM Son","year":"2002","unstructured":"Son SM (2002) Reactive oxygen and nitrogen species in pathogenesis of vascular complications of diabetes. J Diabetes Metab 36:190\u2013198","journal-title":"J Diabetes Metab"},{"key":"8323_CR69","doi-asserted-by":"crossref","unstructured":"Tukov FF, Luyendyk JP, Ganey PE, Roth RA (2007) The role of tumor necrosis factor alpha in lipopolysaccharide\/ranitidine-induced inflammatory liver H.M. Hafezetal. European J Pharmacol 768\u20131211","DOI":"10.1093\/toxsci\/kfm209"},{"key":"8323_CR70","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ecoenv.2005.03.013","volume":"64","author":"A Valavanidis","year":"2006","unstructured":"Valavanidis A, Vlahogianni T, Dassenakis M, Scoullos M (2006) Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants. Ecotoxicol Environ Saf 64:178\u2013189","journal-title":"Ecotoxicol Environ Saf"},{"key":"8323_CR71","doi-asserted-by":"crossref","unstructured":"Viegas CM, Zanatta A, Knebel LA, Schuck PF, Tonin AM, Ferreira Gda C, Amaral AU, Dutra Filho CS, Wannmacher CM, Wajner M (2009) Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. Brain Res 1291:102\u2013112","DOI":"10.1016\/j.brainres.2009.07.021"},{"key":"8323_CR72","first-page":"151","volume-title":"Stereoselectivity of Pesticides: Biological and Chemical Problems","author":"HPM Vijverberg","year":"1988","unstructured":"Vijverberg HPM, Oortgiessn M (1988) Steric structure and action of pyrethroids. In: Ari\u00ebns EJ, van Rensen JJS, Welling W (eds) Stereoselectivity of Pesticides: Biological and Chemical Problems, vol 1. Elsevier, Amsterdam, pp 151\u2013182"},{"key":"8323_CR73","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.envres.2016.05.003","volume":"149","author":"X Wang","year":"2016","unstructured":"Wang X, Martinez MA, Dai M, Chen D, Ares I, Romero A, Castellano V, Martinez M, Rodriguez JL, Martinez-Larranga MR, Anadon A, Yuan Z (2016) Permethrin-induced oxidative stress and toxicity and metabolism. A review. Environ Res 149:86\u2013104","journal-title":"Environ Res"},{"key":"8323_CR74","first-page":"88","volume-title":"Public Health Impact of Pesticides Used in Agriculture","author":"WHO","year":"1990","unstructured":"WHO (1990) Public Health Impact of Pesticides Used in Agriculture. World Health Organization, Geneva, p 88"},{"key":"8323_CR75","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/jcla.1860060110","volume":"6","author":"V Witko","year":"1992","unstructured":"Witko V, Nguyen AT, Descamps-Latscha B (1992) Microtiter plate assay for phagocyte derived taurine-chloramines. J Clin Lab Anal 6:47\u201353","journal-title":"J Clin Lab Anal"},{"key":"8323_CR76","first-page":"84","volume":"39","author":"M Yamashita","year":"1997","unstructured":"Yamashita M, Tanaka J, Ando Y (1997) Human mortality in organophosphate poisoning, vet. Hum Toxicol 39:84\u201385","journal-title":"Hum Toxicol"},{"key":"8323_CR77","first-page":"118","volume":"62","author":"A Zab\u0142ocka","year":"2008","unstructured":"Zab\u0142ocka A, Janusz M (2008) The two faces of reactive oxygen species. Post Hig Med Dosw 62:118\u2013124","journal-title":"Post Hig Med Dosw"},{"key":"8323_CR78","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00417-012-2109-2","volume":"250","author":"Y Zhoo","year":"2012","unstructured":"Zhoo Y, Yang K, Wang F, Liang Y, Peng Y, Shen R, Wong T, Wang N (2012) Associations between metabolic syndrome and syndrome components and retinal microvascular signs in a rural Chinese population: the Handan eye study, Graefes. Arch Clin Exp Ophthalmol 250:1755\u20131763","journal-title":"Arch Clin Exp Ophthalmol"},{"key":"8323_CR79","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.cbi.2010.07.010","volume":"188","author":"JD Ziech","year":"2010","unstructured":"Ziech JD, Franco R, Georgakilas AG, Georgakila S, Malamou-Mitsi V, Schoneveld O, Pappa A, Panayiotidis MI (2010) The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development. Chem Biol Interact 188:334\u2013339","journal-title":"Chem Biol Interact"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-016-8323-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11356-016-8323-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-016-8323-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T06:10:07Z","timestamp":1568700607000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11356-016-8323-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,6]]},"references-count":79,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["8323"],"URL":"https:\/\/doi.org\/10.1007\/s11356-016-8323-4","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,6]]}}}