{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:38:32Z","timestamp":1771335512161,"version":"3.50.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31873031"],"award-info":[{"award-number":["31873031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s11356-020-07732-5","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T05:28:00Z","timestamp":1579584480000},"page":"11337-11348","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Ameliorative effect of naringin against thiram-induced tibial dyschondroplasia in broiler chicken"],"prefix":"10.1007","volume":"27","author":[{"given":"Xiong","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aoyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mudassar","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Waqas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Mehmood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hammad","family":"Qamar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6065-6648","authenticated-orcid":false,"given":"Jiakui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"7732_CR1","doi-asserted-by":"crossref","unstructured":"Adil M, Kandhare AD, Visnagri A, Bodhankar SL (2015) Naringin ameliorates sodium arsenite-induced renal and hepatic toxicity in rats: decisive role of KIM-1, Caspase-3, TGF- , and TNF- . Ren Fail 37 (8):1396\u20131407","DOI":"10.3109\/0886022X.2015.1074462"},{"key":"7732_CR2","doi-asserted-by":"publisher","first-page":"2745352","DOI":"10.1155\/2019\/2745352","volume":"2019","author":"O Ahmed","year":"2019","unstructured":"Ahmed O, Fahim H, Ahmed H, Al-Muzafar H, Ahmed R, Amin K, El-Nahass E, Abdelazeem W (2019a) The preventive effects and the mechanisms of action of navel orange peel hydroethanolic extract, naringin, and naringenin in N-acetyl-p-aminophenol-induced liver injury in Wistar rats. Oxidative Med Cell Longev 2019:2745352","journal-title":"Oxidative Med Cell Longev"},{"key":"7732_CR3","first-page":"153","volume":"14","author":"S Ahmed","year":"2019","unstructured":"Ahmed S, Khan H, Aschner M, Hasan M, Hassan S (2019b) Therapeutic potential of naringin in neurological disorders. Food Chem Toxicol 14:153\u2013164","journal-title":"Food Chem Toxicol"},{"issue":"6","key":"7732_CR4","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.pharep.2019.06.007","volume":"71","author":"N Amini","year":"2019","unstructured":"Amini N, Sarkaki A, Dianat M, Mard S, Ahangarpour A, Badavi M (2019) Protective effects of naringin and trimetazidine on remote effect of acute renal injury on oxidative stress and myocardial injury through Nrf-2 regulation. Pharmacol Rep 71(6):1059\u20131066","journal-title":"Pharmacol Rep"},{"key":"7732_CR5","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/S1532-0456(01)00197-1","volume":"129","author":"J Avanzo","year":"2001","unstructured":"Avanzo J, de Mendon\u00e7a C, Pugine S, de Cerqueira C (2001) Effect of vitamin E and selenium on resistance to oxidative stress in chicken superficial pectoralis muscle. Comp Biochem Physiol C Toxicol Pharmacol 129:163\u2013173","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"7732_CR6","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1134\/S0026261710020074","volume":"79","author":"E Bogatyrenko","year":"2010","unstructured":"Bogatyrenko E, Buzoleva CZ (2010) Potential probiotics of the far eastern trepang Apostychopus japonicus producing digestive enzymes. Microbiology 79:173\u2013177","journal-title":"Microbiology"},{"key":"7732_CR7","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/0891-5849(94)90167-8","volume":"17","author":"J Chen","year":"1994","unstructured":"Chen J, Yu B (1994) Alterations in mitochondrial membrane fluidity by lipid peroxidation products. Free Radic Biol Med 17:411\u2013418","journal-title":"Free Radic Biol Med"},{"key":"7732_CR8","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1242\/dev.01649","volume":"132","author":"C Colnot","year":"2005","unstructured":"Colnot C, Fuente L, Huang S, Hu D, Lu C, St-Jacques B, Helms J (2005) Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development 132:1057\u20131067","journal-title":"Development"},{"key":"7732_CR9","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1002\/ijc.23564","volume":"123","author":"G Cutler","year":"2008","unstructured":"Cutler G, Nettleton J, Ross J, Harnack L, Jacobs D, Scrafford C, Barraj L, Mink P, Robien K (2008) Dietary flavonoid intake and risk of cancer in postmenopausal women: the Iowa Women\u2019s Health study. Int J Cancer 123:664\u2013671","journal-title":"Int J Cancer"},{"key":"7732_CR10","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.phymed.2018.03.051","volume":"42","author":"A El-Desoky","year":"2018","unstructured":"El-Desoky A, Abdel-Rahman R, Ahmed O, El-Beltagi H, Hattori M (2018) Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: in vitro and in vivo evidence. Phytomedicine 42:126\u2013134","journal-title":"Phytomedicine"},{"key":"7732_CR11","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S1050-1738(00)00074-8","volume":"10","author":"H Gerber","year":"2000","unstructured":"Gerber H, Ferrara N (2000) Angiogenesis and bone growth. Trends Cardiovasc Med 10:223\u2013228","journal-title":"Trends Cardiovasc Med"},{"key":"7732_CR12","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1017\/S1751731116001105","volume":"11","author":"P Groves","year":"2017","unstructured":"Groves P, Muir W (2017) Earlier hatching time predisposes Cobb broiler chickens to tibial dyschondroplasia. Animal 11:112\u2013120","journal-title":"Animal"},{"key":"7732_CR13","doi-asserted-by":"crossref","unstructured":"Hu N, Gong X, Yin S, Li Q, Chen H, Li Y, Li F, Qing L, Yang J, Zhu S, Wang J, Li J (2019) Saxagliptin suppresses degradation of type II collagen and aggrecan in primary human chondrocytes: a therapeutic implication in osteoarthritis. Artif. Cells. Nanomed Biotechnol 47: 3239\u20133245","DOI":"10.1080\/21691401.2019.1647223"},{"key":"7732_CR14","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.7150\/ijbs.22670","volume":"13","author":"S Huang","year":"2017","unstructured":"Huang S, Tong X, Rehman M, Wang M, Zhang L, Wang L, Li J, Yang S (2017) Oxygen supplementation ameliorates tibial development via stimulating vascularization in Tibetan chickens at high altitudes. Int J Biol Sci 13:1547\u20131559","journal-title":"Int J Biol Sci"},{"key":"7732_CR15","doi-asserted-by":"publisher","first-page":"3680","DOI":"10.1038\/s41598-018-22109-y","volume":"8","author":"S Huang","year":"2018","unstructured":"Huang S, Zhang L, Zhang J, Rehman M, Tong X, Qiu G, Jiang X, Iqbal M, Shahzad M, Shen Y, Li J (2018) Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens. Sci Rep 8:3680","journal-title":"Sci Rep"},{"key":"7732_CR16","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/0891-5849(90)90131-2","volume":"9","author":"D Janero","year":"1990","unstructured":"Janero D (1990) Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic Biol Med 9:515\u2013540","journal-title":"Free Radic Biol Med"},{"issue":"3","key":"7732_CR17","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1101\/gad.8.3.277","volume":"8","author":"A Karaplis","year":"1994","unstructured":"Karaplis A, Luz A, Glowacki J, Bronson R, Tybulewicz V, Kronenberg H, Mulligan R (1994) Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev 8(3):277\u2013289","journal-title":"Genes Dev"},{"issue":"3","key":"7732_CR18","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1242\/dev.127.3.543","volume":"127","author":"S Karp","year":"2000","unstructured":"Karp S, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon A (2000) Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and independent pathways. Development 127(3):543\u2013548","journal-title":"Development"},{"key":"7732_CR19","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1017\/S1751731116002160","volume":"11","author":"E Kaukonen","year":"2017","unstructured":"Kaukonen E, Norring M, Valros A (2017) Perches and elevated platforms in commercial broiler farms: use and effect on walking ability, incidence of tibial dyschondroplasia and bone mineral content. Animal 11:864\u2013871","journal-title":"Animal"},{"issue":"12","key":"7732_CR20","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.3390\/ijms17122045","volume":"17","author":"T Komori","year":"2016","unstructured":"Komori T (2016) Cell death in chondrocytes, osteoblasts, and osteocytes. Int J Mol Sci 17(12):2045","journal-title":"Int J Mol Sci"},{"key":"7732_CR21","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1177\/0885328218809239","volume":"33","author":"M Lai","year":"2018","unstructured":"Lai M, Jin Z, Yan M, Zhu J, Yan X, Xu K (2018) The controlled naringin release from TiO2 nanotubes to regulate osteoblast differentiation. J Biomater Appl 33:673\u2013680","journal-title":"J Biomater Appl"},{"key":"7732_CR22","doi-asserted-by":"publisher","first-page":"502","DOI":"10.3390\/nu9050502","volume":"9","author":"T Lara","year":"2017","unstructured":"Lara T, Vincenzo C (2017) Nutraceutical value of Citrus flavanones and their implications in cardiovascular disease. Nutrients 9:502","journal-title":"Nutrients"},{"issue":"11","key":"7732_CR23","doi-asserted-by":"publisher","first-page":"5109","DOI":"10.1210\/endo.137.11.8895385","volume":"137","author":"K Lee","year":"1996","unstructured":"Lee K, Lanske B, Karaplis DJ, Kohno H, Nissenson R, Kronenberg H, Segre G (1996) Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology 137(11):5109\u20135118","journal-title":"Endocrinology"},{"key":"7732_CR24","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.rvsc.2007.11.008","volume":"84","author":"J Li","year":"2008","unstructured":"Li J, Bi D, Pan S, Zhang Y, Zhou D (2008) Effects of high dietary vitamin A supplementation on tibial dyschondroplasia, skin pigmentation and growth performance in avian broilers. Res Vet Sci 84:409\u2013412","journal-title":"Res Vet Sci"},{"key":"7732_CR25","doi-asserted-by":"crossref","unstructured":"Liu L, Tao W, Pan W, Li L, Yu Q, Zhang D, Jiang J (2018) Hydroxysafflor yellow a promoted bone mineralization and inhibited bone resorption which reversed glucocorticoids-induced osteoporosis. Biomed Res Int:1\u20138","DOI":"10.1155\/2018\/6762146"},{"key":"7732_CR26","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1002\/etc.2925","volume":"34","author":"A Lopez-Antia","year":"2015","unstructured":"Lopez-Antia A, Ortiz-Santaliestra M, Garc\u00eda-de B, Camarero P, Mougeot F, Mateo R (2015) Adverse effects of thiram-treated seed ingestion on the reproductive performance and the offspring immune function of the red-legged partridge. Environ Toxicol Chem 34:1320\u20131329","journal-title":"Environ Toxicol Chem"},{"issue":"2","key":"7732_CR27","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1039\/C2FO30213F","volume":"4","author":"Y Lv","year":"2013","unstructured":"Lv Y, Zhang B, Xing G, Wang F, Hu Z (2013) Protective effect of naringenin against acetaminophen-induced acute liver injury in metallothionein (MT)-null mice. Food Funct 4(2):297\u2013302","journal-title":"Food Funct"},{"key":"7732_CR28","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.intimp.2018.09.019","volume":"65","author":"Z Lv","year":"2018","unstructured":"Lv Z, Wu W, Ge S, Jia R, Lin T, Yuan Y, Kuang H, Yang B, Wu L, Wei J, Zhang D (2018) Naringin protects against perfluorooctane sulfonate-induced liver injury by modulating NRF2 and NF-\u03baB in mice. Int Immunopharmacol 65:140\u2013147","journal-title":"Int Immunopharmacol"},{"key":"7732_CR29","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1038\/sj.bjc.6600078","volume":"86","author":"M Marikovsky","year":"2002","unstructured":"Marikovsky M (2002) Thiram inhibits angiogenesis and slows the development of experimental tumours in mice. Br J Cancer 86:779\u2013787","journal-title":"Br J Cancer"},{"key":"7732_CR30","doi-asserted-by":"crossref","unstructured":"McMahon AP, Ingham PW, Tabin CJ (2003) Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol 53:1\u2013114","DOI":"10.1016\/S0070-2153(03)53002-2"},{"key":"7732_CR31","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1038\/s41598-018-20562-3","volume":"8","author":"K Mehmood","year":"2018","unstructured":"Mehmood K, Zhang H, Li K, Wang L, Rehman M, Nabi F, Iqbal M, Luo H, Shahzad M, Li J (2018) Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1\u03b1\/VEGF signaling pathway in chickens. Sci Rep 8:2495","journal-title":"Sci Rep"},{"key":"7732_CR32","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.ecoenv.2018.10.080","volume":"168","author":"K Mehmood","year":"2019","unstructured":"Mehmood K, Zhang H, Jiang X, Yao W, Tong X, Iqbal M, Rehman M, Iqbal M, Waqas M, Qamar H, Zhang J, Li J (2019) Ligustrazine recovers thiram-induced tibial dyschondroplasia in chickens: involvement of new molecules modulating integrin beta 3. Ecotoxicol Environ Saf 168:205\u2013211","journal-title":"Ecotoxicol Environ Saf"},{"key":"7732_CR33","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1093\/ajcn\/85.3.895","volume":"85","author":"P Mink","year":"2007","unstructured":"Mink P, Scrafford C, Barraj L, Harnack L, Hong C, Nettleton J, Jacobs D (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 85:895\u2013909","journal-title":"Am J Clin Nutr"},{"key":"7732_CR34","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1002\/jemt.23153","volume":"82","author":"U Pazzaglia","year":"2019","unstructured":"Pazzaglia U, Reguzzoni M, Casati L, Minini A, Salvi A, Sibilia V (2019) Long bone human anlage longitudinal and circumferential growth in the fetal period and comparison with the growth plate cartilage of the postnatal age. Microsc Res Tech 82:190\u2013198","journal-title":"Microsc Res Tech"},{"key":"7732_CR35","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s002239900568","volume":"63","author":"M Pines","year":"1998","unstructured":"Pines M, Knopov V, Genina O, Hurwitz S, Faerman A, Gerstenfeld L, Leach R (1998) Development of avian Tibial dyschondroplasia: gene expression and protein synthesis. Calcif Tissue Int 63:521\u2013527","journal-title":"Calcif Tissue Int"},{"key":"7732_CR36","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/S2221-1691(12)60249-4","volume":"2","author":"B Ramesh","year":"2012","unstructured":"Ramesh B, Karuna R, Sreenivasa R, Haritha K, Sai M, Sasi B, Saralakumari D (2012) Effect of Commiphora mukul gum resin on hepatic marker enzymes, lipid peroxidation and antioxidants status in pancreas and heart of streptozotocin induced diabetic rats. Asian Pac J Trop Biomed 2:895\u2013900","journal-title":"Asian Pac J Trop Biomed"},{"key":"7732_CR37","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1080\/20014091091805","volume":"41","author":"A Schaafsma","year":"2001","unstructured":"Schaafsma A, Vries P, Saris W (2001) Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr 41:225\u2013249","journal-title":"Crit Rev Food Sci Nutr"},{"key":"7732_CR38","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1637\/10781-012614-ResNote.1","volume":"58","author":"M Shahzad","year":"2014","unstructured":"Shahzad M, Gao J, Qin P, Liu J, Wang Z, Zhang D, Li J (2014) Expression of genes encoding matrilin-3 and cyclin-I during the impairment and recovery of chicken growth plate in tibial dyschondroplasia. Avian Dis 58:468\u2013473","journal-title":"Avian Dis"},{"issue":"6","key":"7732_CR39","first-page":"1741","volume":"40","author":"W Shangguan","year":"2017","unstructured":"Shangguan W, Zhang Y, Li Z, Tang L, Shao J, Li H (2017) Naringin inhibits vascular endothelial cell apoptosis via endoplasmic reticulum stress- and mitochondrial-mediated pathways and promotes intraosseous angiogenesis in ovariectomized rats. Int J Mol Med 40(6):1741\u20131749","journal-title":"Int J Mol Med"},{"key":"7732_CR40","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.1091\/mbc.e06-08-0743","volume":"18","author":"A Shimoyama","year":"2007","unstructured":"Shimoyama A, Wada M, Ikeda F, Hata K, Matsubara T, Nifuji A, Noda M, Amano K, Yamaguchi A, Nishimura R, Yoneda T (2007) Ihh\/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol Biol Cell 18:2411\u20132418","journal-title":"Mol Biol Cell"},{"key":"7732_CR41","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.cbi.2016.10.020","volume":"261","author":"N Song","year":"2017","unstructured":"Song N, Zhao Z, Ma X, Sun X, Ma J, Li F, Sun L, Lv J (2017) Naringin promotes fracture healing through stimulation of angiogenesis by regulating the VEGF\/VEGFR-2 signaling pathway in osteoporotic rats. Chem Biol Interact 261:11\u201317","journal-title":"Chem Biol Interact"},{"issue":"16","key":"7732_CR42","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.1101\/gad.13.16.2072","volume":"13","author":"B St-Jacques","year":"1999","unstructured":"St-Jacques B, Hammerschmidt M, McMahon A (1999) Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev 13(16):2072\u20132086","journal-title":"Genes Dev"},{"key":"7732_CR43","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1016\/j.fct.2012.02.008","volume":"50","author":"Y Tang","year":"2012","unstructured":"Tang Y, Gao C, Xing M, Li Y, Zhu L, Wang D, Yang X, Liu L, Yao P (2012) Quercetin prevents ethanol-induced dyslipidemia and mitochondrial oxidative damage. Food Chem Toxicol 50:1194\u20132000","journal-title":"Food Chem Toxicol"},{"issue":"6","key":"7732_CR44","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1359\/jbmr.2000.15.6.1045","volume":"15","author":"B Van der Eerden","year":"2000","unstructured":"Van der Eerden B, Karperien M, Gevers E, L\u00f6wik C, Wit J (2000) Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth. J Bone Miner Res 15(6):1045\u20131055","journal-title":"J Bone Miner Res"},{"key":"7732_CR45","doi-asserted-by":"publisher","first-page":"2858","DOI":"10.3382\/ps.2012-02385","volume":"91","author":"W Van","year":"2012","unstructured":"Van W, Applegate T, Lilburn M, Karcher D (2012) A comparison of long bone development in historical and contemporary ducks. Poult Sci 91:2858\u20132865","journal-title":"Poult Sci"},{"issue":"5275","key":"7732_CR46","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1126\/science.273.5275.613","volume":"273","author":"A Vortkamp","year":"1996","unstructured":"Vortkamp A, Lee K, Lanske B, Segre G, Kronenberg H, Tabin C (1996) Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273(5275):613\u2013622","journal-title":"Science"},{"key":"7732_CR47","unstructured":"Wang D, Ma W, Wang Fu, Dong J, Wang D, Sun B, Wang B (2015) Stimulation of Wnt\/\u03b2-catenin signaling to improve bone development by naringin via interacting with AMPK and Akt. Cell. Physiol Biochem 36: 1563\u20131576"},{"key":"7732_CR48","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1095\/biolreprod23.1.40","volume":"23","author":"R Weppelman","year":"1980","unstructured":"Weppelman R, Long R, Van I, Taylor J, Tolman R, Peterson L, Olson G (1980) Antifertility effects of dithiocarbamates in laying hens. Biol Reprod 23:40\u201346","journal-title":"Biol Reprod"},{"key":"7732_CR49","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jep.2013.10.030","volume":"151","author":"G Xu","year":"2014","unstructured":"Xu G, Zhao M, Sun N, Ju C, Jia T (2014) Effect of the RW-Cb and its active ingredient like P-acid and P-aldehyde on primary rat osteoblasts. J Ethnopharmacol 151:237\u2013241","journal-title":"J Ethnopharmacol"},{"key":"7732_CR50","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.fsi.2015.05.032","volume":"45","author":"G Yang","year":"2015","unstructured":"Yang G, Tian X, Dong S, Peng M, Wang D (2015) Effects of dietary Bacillus cereus G19, B. cereus BC-01, and Paracoccus marcusii DB11 supplementation on the growth, immune response, and expression of immune-related genes in coelomocytes and intestine of the sea cucumber (Apostichopus japonicus Selenka). Fish Shellfsh Immun 45:800\u2013807","journal-title":"Fish Shellfsh Immun"},{"key":"7732_CR51","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1080\/10717544.2019.1568620","volume":"26","author":"X Yang","year":"2019","unstructured":"Yang X, Almassri H, Zhang Q, Ma Y, Zhang D, Chen M, Wu X (2019) Electrosprayed naringin-loaded microsphere\/SAIB hybrid depots enhance bone formation in a mouse calvarial defect model. Drug Deliv 26:137\u2013146","journal-title":"Drug Deliv"},{"key":"7732_CR52","doi-asserted-by":"crossref","unstructured":"Ye F, Xu H, Yin H, Zhao X, Li D, Zhu Q, Wang Y (2019) The role of BMP6 in the proliferation and differentiation of chicken cartilage cells. PLoS One 14","DOI":"10.1371\/journal.pone.0204384"},{"key":"7732_CR53","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s11101-017-9497-1","volume":"16","author":"L Yi","year":"2017","unstructured":"Yi L, Ma S, Ren D (2017) Phytochemistry and bioactivity of Citrus flavonoids: a focus on antioxidant, anti-inflammatory, anticancer and cardiovascular protection activities. Phytochem Rev 16:479\u2013511","journal-title":"Phytochem Rev"},{"key":"7732_CR54","doi-asserted-by":"publisher","first-page":"28264","DOI":"10.1007\/s11356-018-2824-2","volume":"25","author":"H Zhang","year":"2018","unstructured":"Zhang H, Mehmood K, Jiang X, Yao W, Iqbal M, Waqas M, Rehman M, Li A, Shen Y, Li J (2018a) Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens. Environ Sci Pollut Res Int 25:28264\u201328274","journal-title":"Environ Sci Pollut Res Int"},{"key":"7732_CR55","doi-asserted-by":"publisher","first-page":"123","DOI":"10.3389\/fphar.2018.00123","volume":"9","author":"H Zhang","year":"2018","unstructured":"Zhang H, Mehmood K, Li K, Rehman M, Jiang X, Huang S, Wang L, Zhang L, Tong X, Nabi F, Yao W, Iqbal M, Shahzad M, Li J (2018b) Icariin ameliorate thiram-induced tibial dyschondroplasia via regulation of WNT4 and VEGF expression in broiler chickens. Front Pharmacol 9:123","journal-title":"Front Pharmacol"},{"issue":"1","key":"7732_CR56","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s10753-015-0260-8","volume":"39","author":"Y Zhao","year":"2016","unstructured":"Zhao Y, Li Z, Wang W, Zhang H, Chen J, Su P, Liu L, Li W (2016) Naringin protects against cartilage destruction in osteoarthritis through repression of NF-\u03baB signaling pathway. Inflammation 39(1):385\u2013392","journal-title":"Inflammation"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-07732-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11356-020-07732-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-07732-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T02:30:36Z","timestamp":1665541836000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11356-020-07732-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,21]]},"references-count":56,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["7732"],"URL":"https:\/\/doi.org\/10.1007\/s11356-020-07732-5","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,21]]},"assertion":[{"value":"11 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}