{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:34:36Z","timestamp":1792784076534,"version":"4.5.0"},"reference-count":143,"publisher":"Springer Science and Business Media LLC","issue":"34","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Universidad Cooperativa de Colombia","award":["INV2194"],"award-info":[{"award-number":["INV2194"]}],"id":[{"id":"https:\/\/ror.org\/04td15k45","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Corporaci\u00f3n Universitaria Remington","id":[{"id":"https:\/\/ror.org\/04zwxg371","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007637","name":"Colciencias","doi-asserted-by":"crossref","award":["141580763047"],"award-info":[{"award-number":["141580763047"]}],"id":[{"id":"10.13039\/100007637","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s11356-020-10574-w","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T07:02:57Z","timestamp":1598943777000},"page":"42390-42404","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":387,"title":["Inflammatory effects of particulate matter air pollution"],"prefix":"10.1007","volume":"27","author":[{"given":"Rub\u00e9n D.","family":"Arias-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6085-855X","authenticated-orcid":false,"given":"Natalia A.","family":"Taborda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3433-7288","authenticated-orcid":false,"given":"Diana M.","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhon Fredy","family":"Narvaez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3586-5701","authenticated-orcid":false,"given":"Jazm\u00edn","family":"Porras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9200-5698","authenticated-orcid":false,"given":"Juan C.","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"key":"10574_CR1","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s40572-017-0134-3","volume":"4","author":"JL Allen","year":"2017","unstructured":"Allen JL, Klocke C, Morris-Schaffer K, Conrad K, Sobolewski M, Cory-Slechta DA (2017) Cognitive effects of air pollution exposures and potential mechanistic underpinnings. Curr Environ Health Rep 4:180\u2013191. https:\/\/doi.org\/10.1007\/s40572-017-0134-3","journal-title":"Curr Environ Health Rep"},{"key":"10574_CR2","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jocn.2017.04.028","volume":"43","author":"RM Babadjouni","year":"2017","unstructured":"Babadjouni RM, Hodis DM, Radwanski R, Durazo R, Patel A, Liu Q, Mack WJ (2017) Clinical effects of air pollution on the central nervous system; a review. J Clin Neurosci 43:16\u201324. https:\/\/doi.org\/10.1016\/j.jocn.2017.04.028","journal-title":"J Clin Neurosci"},{"key":"10574_CR3","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1164\/rccm.200807-1097OC","volume":"179","author":"A Baccarelli","year":"2009","unstructured":"Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J (2009) Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 179:572\u2013578. https:\/\/doi.org\/10.1164\/rccm.200807-1097OC","journal-title":"Am J Respir Crit Care Med"},{"key":"10574_CR4","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000212","volume":"2","author":"A Bellavia","year":"2013","unstructured":"Bellavia A, Urch B, Speck M, Brook RD, Scott JA, Albetti B, Behbod B, North M, Valeri L, Bertazzi PA, Silverman F, Gold D, A. Baccarelli A (2013) DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments. J Am Heart Assoc 2:e000212. https:\/\/doi.org\/10.1161\/JAHA.113.000212","journal-title":"J Am Heart Assoc"},{"key":"10574_CR5","doi-asserted-by":"publisher","first-page":"158093","DOI":"10.1155\/2013\/158093","volume":"2013","author":"R Bengalli","year":"2013","unstructured":"Bengalli R, Molteni E, Longhin E, Refsnes M, Camatini M, Gualtieri M (2013) Release of IL-1 \u03b2 triggered by Milan summer PM10: molecular pathways involved in the cytokine release. Biomed Res Int 2013:158093\u2013158099. https:\/\/doi.org\/10.1155\/2013\/158093","journal-title":"Biomed Res Int"},{"key":"10574_CR6","doi-asserted-by":"publisher","unstructured":"Blount RJ, Djawe K, Daly KR, Jarlsberg LG, Fong S, Balmes J, Miller RF, Walzer PD, Huang L, on behalf of the International HIV-associated Opportunistic Pneumonias (IHOP) Study (2013) Ambient air pollution associated with suppressed serologic responses to Pneumocystis jirovecii in a prospective cohort of HIV-infected patients with Pneumocystis pneumonia. PLoS ONE:8. https:\/\/doi.org\/10.1371\/journal.pone.0080795","DOI":"10.1371\/journal.pone.0080795"},{"key":"10574_CR7","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1515\/tnsci-2016-0005","volume":"7","author":"S Brockmeyer","year":"2016","unstructured":"Brockmeyer S, D\u2019Angiulli A (2016) How air pollution alters brain development: the role of neuroinflammation. Transl Neurosci 7:24\u201330. https:\/\/doi.org\/10.1515\/tnsci-2016-0005","journal-title":"Transl Neurosci"},{"key":"10574_CR8","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1161\/CIR.0b013e3181dbece1","volume":"121","author":"RD Brook","year":"2010","unstructured":"Brook RD, Rajagopalan S, Pope CA et al (2010) Particulate matter air pollution and cardiovascular disease. Circulation 121:2331\u20132378. https:\/\/doi.org\/10.1161\/CIR.0b013e3181dbece1","journal-title":"Circulation"},{"key":"10574_CR9","doi-asserted-by":"publisher","first-page":"e18525","DOI":"10.1371\/journal.pone.0018525","volume":"6","author":"GRS Budinger","year":"2011","unstructured":"Budinger GRS, McKell JL, Urich D et al (2011) Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms. PLoS One 6:e18525. https:\/\/doi.org\/10.1371\/journal.pone.0018525","journal-title":"PLoS One"},{"key":"10574_CR10","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1161\/HYPERTENSIONAHA.116.07218","volume":"68","author":"Y Cai","year":"2016","unstructured":"Cai Y, Zhang B, Ke W, Feng B, Lin H, Xiao J, Zeng W, Li X, Tao J, Yang Z, Ma W, Liu T (2016) Associations of short-term and long-term exposure to ambient air pollutants with hypertension: a systematic review and meta-analysis. Hypertension 68:62\u201370. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.116.07218","journal-title":"Hypertension"},{"key":"10574_CR11","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.3390\/ijerph15091918","volume":"15","author":"J Cai","year":"2018","unstructured":"Cai J, Yu S, Pei Y, Peng C, Liao Y, Liu N, Ji J, Cheng J (2018) Association between airborne fine particulate matter and residents\u2019 cardiovascular diseases, ischemic heart disease and cerebral vascular disease mortality in areas with lighter air pollution in China. Int J Environ Res Public Health 15:1918. https:\/\/doi.org\/10.3390\/ijerph15091918","journal-title":"Int J Environ Res Public Health"},{"key":"10574_CR12","doi-asserted-by":"publisher","first-page":"108541","DOI":"10.1016\/j.envres.2019.108541","volume":"176","author":"L Cai","year":"2019","unstructured":"Cai L, Wang S, Gao P, Shen X, Jalaludin B, Bloom MS, Wang Q, Bao J, Zeng X, Gui Z, Chen Y, Huang C (2019) Effects of ambient particulate matter on fasting blood glucose among primary school children in Guangzhou, China. Environ Res 176:108541. https:\/\/doi.org\/10.1016\/j.envres.2019.108541","journal-title":"Environ Res"},{"key":"10574_CR13","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1080\/01926230490520232","volume":"32","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2004","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Reed W, Maronpot RR, Henriquez-Rold\u00e1n C, Delgado-Chavez R, Calder\u00f3n-Garcidue\u00f1as A, Dragustinovis I, Franco-Lira M, Arag\u00f3n-Flores M, Solt AC, Altenburg M, Torres-Jard\u00f3n R, Swenberg JA (2004) Brain inflammation and Alzheimer\u2019s-like pathology in individuals exposed to severe air pollution. Toxicol Pathol 32:650\u2013658. https:\/\/doi.org\/10.1080\/01926230490520232","journal-title":"Toxicol Pathol"},{"key":"10574_CR14","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1080\/01926230601059985","volume":"35","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2007","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Franco-Lira M, Torres-Jard\u00f3n R, Henriquez-Rold\u00e1n C, Barrag\u00e1n-Mej\u00eda G, Valencia-Salazar G, Gonzal\u00e9z-Maciel A, Reynoso-Robles R, Villarreal-Calder\u00f3n R, Reed W (2007a) Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology. Toxicol Pathol 35:154\u2013162. https:\/\/doi.org\/10.1080\/01926230601059985","journal-title":"Toxicol Pathol"},{"key":"10574_CR15","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1289\/ehp.9641","volume":"115","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2007","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Vincent R, Mora-Tiscare\u00f1o A, Franco-Lira M, Henr\u00edquez-Rold\u00e1n C, Barrag\u00e1n-Mej\u00eda G, Garrido-Garc\u00eda L, Camacho-Reyes L, Valencia-Salazar G, Paredes R, Romero L, Osnaya H, Villarreal-Calder\u00f3n R, Torres-Jard\u00f3n R, Hazucha MJ, Reed W (2007b) Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollution. Environ Health Perspect 115:1248\u20131253. https:\/\/doi.org\/10.1289\/ehp.9641","journal-title":"Environ Health Perspect"},{"key":"10574_CR16","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.bandc.2008.04.008","volume":"68","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2008","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Mora-Tiscare\u00f1o A, Ontiveros E, G\u00f3mez-Garza G, Barrag\u00e1n-Mej\u00eda G, Broadway J, Chapman S, Valencia-Salazar G, Jewells V, Maronpot RR, Henr\u00edquez-Rold\u00e1n C, P\u00e9rez-Guill\u00e9 B, Torres-Jard\u00f3n R, Herrit L, Brooks D, Osnaya-Brizuela N, Monroy ME, Gonz\u00e1lez-Maciel A, Reynoso-Robles R, Villarreal-Calderon R, Solt AC, Engle RW (2008) Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs. Brain Cogn 68:117\u2013127. https:\/\/doi.org\/10.1016\/j.bandc.2008.04.008","journal-title":"Brain Cogn"},{"key":"10574_CR17","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3233\/JAD-2011-110722","volume":"28","author":"L Calder\u00f3n-Garcidue\u00f1as","year":"2012","unstructured":"Calder\u00f3n-Garcidue\u00f1as L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Ch\u00e1vez R, Torres-Jard\u00f3n R, Gonz\u00e1lez-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P (2012) Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis 28:93\u2013107. https:\/\/doi.org\/10.3233\/JAD-2011-110722","journal-title":"J Alzheimers Dis"},{"key":"10574_CR18","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.3390\/ijms17091403","volume":"17","author":"S Capistrano","year":"2016","unstructured":"Capistrano S, Zakarya R, Chen H, Oliver B (2016) Biomass smoke exposure enhances rhinovirus-induced inflammation in primary lung fibroblasts. Int J Mol Sci 17:1403. https:\/\/doi.org\/10.3390\/ijms17091403","journal-title":"Int J Mol Sci"},{"key":"10574_CR19","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.envres.2018.06.016","volume":"166","author":"M Carugno","year":"2018","unstructured":"Carugno M, Dentali F, Mathieu G, Fontanella A, Mariani J, Bordini L, Milani GP, Consonni D, Bonzini M, Bollati V, Pesatori AC (2018) PM10 exposure is associated with increased hospitalizations for respiratory syncytial virus bronchiolitis among infants in Lombardy, Italy. Environ Res 166:452\u2013457. https:\/\/doi.org\/10.1016\/j.envres.2018.06.016","journal-title":"Environ Res"},{"key":"10574_CR20","unstructured":"C\u00e9sar AA (2012) Diagnosis and control of particulate matter: total suspended particles PM10 breathable fraction. Luna Azul 195\u2013213"},{"key":"10574_CR21","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1002\/ana.24460","volume":"78","author":"JC Chen","year":"2015","unstructured":"Chen JC, Wang X, Wellenius GA, Serre ML, Driscoll I, Casanova R, McArdle JJ, Manson JAE, Chui HC, Espeland MA (2015) Ambient air pollution and neurotoxicity on brain structure: evidence from women\u2019s health initiative memory study. Ann Neurol 78:466\u2013476. https:\/\/doi.org\/10.1002\/ana.24460","journal-title":"Ann Neurol"},{"key":"10574_CR22","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.envpol.2017.01.037","volume":"223","author":"S-Y Chen","year":"2017","unstructured":"Chen S-Y, Chan C-C, Su T-C (2017) Particulate and gaseous pollutants on inflammation, thrombosis, and autonomic imbalance in subjects at risk for cardiovascular disease. Environ Pollut 223:403\u2013408. https:\/\/doi.org\/10.1016\/j.envpol.2017.01.037","journal-title":"Environ Pollut"},{"key":"10574_CR23","doi-asserted-by":"publisher","unstructured":"Chen X, Liu J, Zhou J, Wang J, Chen C, Song Y, Pan J (2018) Urban particulate matter (PM) suppresses airway antibacterial defence 19:5. https:\/\/doi.org\/10.1186\/s12931-017-0700-0","DOI":"10.1186\/s12931-017-0700-0"},{"key":"10574_CR24","doi-asserted-by":"publisher","first-page":"13053","DOI":"10.3390\/ijerph121013053","volume":"12","author":"M-H Cheng","year":"2015","unstructured":"Cheng M-H, Chiu H-F, Yang C-Y (2015) Coarse particulate air pollution associated with increased risk of hospital admissions for respiratory diseases in a Tropical City, Kaohsiung, Taiwan. Int J Environ Res Public Health 12:13053\u201313068. https:\/\/doi.org\/10.3390\/ijerph121013053","journal-title":"Int J Environ Res Public Health"},{"key":"10574_CR25","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1289\/EHP134","volume":"124","author":"H Cheng","year":"2016","unstructured":"Cheng H, Saffari A, Sioutas C, Forman HJ, Morgan TE, Finch CE (2016) Nanoscale particulate matter from urban traffic rapidly induces oxidative stress and inflammation in olfactory epithelium with concomitant effects on brain. Environ Health Perspect 124:1537\u20131546. https:\/\/doi.org\/10.1289\/EHP134","journal-title":"Environ Health Perspect"},{"key":"10574_CR26","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1289\/ehp.1002286","volume":"119","author":"TW Cherng","year":"2011","unstructured":"Cherng TW, Paffett ML, Jackson-Weaver O, Campen MJ, Walker BR, Kanagy NL (2011) Mechanisms of diesel-induced endothelial nitric oxide synthase dysfunction in coronary arterioles. Environ Health Perspect 119:98\u2013103. https:\/\/doi.org\/10.1289\/ehp.1002286","journal-title":"Environ Health Perspect"},{"key":"10574_CR27","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.envres.2019.04.030","volume":"175","author":"SA Choe","year":"2019","unstructured":"Choe SA, Eliot MN, Savitz DA, Wellenius GA (2019) Ambient air pollution during pregnancy and risk of gestational diabetes in New York City. Environ Res 175:414\u2013420. https:\/\/doi.org\/10.1016\/j.envres.2019.04.030","journal-title":"Environ Res"},{"key":"10574_CR28","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1097\/JOM.0b013e3181ceff7a","volume":"52","author":"KJ Chuang","year":"2010","unstructured":"Chuang KJ, Yan YH, Cheng TJ (2010) Effect of air pollution on blood pressure, blood lipids, and blood sugar: a population-based approach. J Occup Environ Med 52:258\u2013262. https:\/\/doi.org\/10.1097\/JOM.0b013e3181ceff7a","journal-title":"J Occup Environ Med"},{"key":"10574_CR29","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1177\/1533317518777859","volume":"33","author":"G Cipriani","year":"2018","unstructured":"Cipriani G, Danti S, Carlesi C, Borin G (2018) Danger in the air: air pollution and cognitive dysfunction. Am J Alzheimers Dis Dementias 33:333\u2013341. https:\/\/doi.org\/10.1177\/1533317518777859","journal-title":"Am J Alzheimers Dis Dementias"},{"key":"10574_CR30","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/EDE.0B013E3182770237","volume":"24","author":"AW Correia","year":"2013","unstructured":"Correia AW, Pope CA III, Dockery DW, Wang Y, Ezzati M, Dominici F (2013) The effect of air pollution control on life expectancy in the United States: an analysis of 545 US counties for the period 2000 to 2007. Epidemiology Camb Mass 24:23\u201331. https:\/\/doi.org\/10.1097\/EDE.0B013E3182770237","journal-title":"Epidemiology Camb Mass"},{"key":"10574_CR31","doi-asserted-by":"publisher","first-page":"AnnalsATS.20181","DOI":"10.1513\/AnnalsATS.201810-691OC","volume":"16","author":"DP Croft","year":"2018","unstructured":"Croft DP, Zhang W, Lin S et al (2018) The association between respiratory infection and air pollution in the setting of air quality policy and economic change. Ann Am Thorac Soc 16:AnnalsATS.201810-691OC. https:\/\/doi.org\/10.1513\/AnnalsATS.201810-691OC","journal-title":"Ann Am Thorac Soc"},{"key":"10574_CR32","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1093\/aje\/kwu234","volume":"180","author":"LA Darrow","year":"2014","unstructured":"Darrow LA, Klein M, Flanders WD, Mulholland JA, Tolbert PE, Strickland MJ (2014) Air pollution and acute respiratory infections among children 0-4 years of age: an 18-year time-series study. Am J Epidemiol 180:968\u2013977. https:\/\/doi.org\/10.1093\/aje\/kwu234","journal-title":"Am J Epidemiol"},{"key":"10574_CR33","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.etap.2018.04.001","volume":"60","author":"MA de los Andrade-Oliva","year":"2018","unstructured":"de los Andrade-Oliva MA, Aztatzi-Aguilar OG, Garc\u00eda-Sierra F et al (2018) Effect of in vivo exposure to ambient fine particles (PM2.5) on the density of dopamine D2-like receptors and dopamine-induced [35S]-GTP\u03b3S binding in rat prefrontal cortex and striatum membranes. Environ Toxicol Pharmacol 60:58\u201365. https:\/\/doi.org\/10.1016\/j.etap.2018.04.001","journal-title":"Environ Toxicol Pharmacol"},{"key":"10574_CR34","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.envpol.2018.05.044","volume":"241","author":"M Dolci","year":"2018","unstructured":"Dolci M, Favero C, Bollati V, Campo L, Cattaneo A, Bonzini M, Villani S, Ticozzi R, Ferrante P, Delbue S (2018) Particulate matter exposure increases JC polyomavirus replication in the human host. Environ Pollut 241:234\u2013239. https:\/\/doi.org\/10.1016\/j.envpol.2018.05.044","journal-title":"Environ Pollut"},{"key":"10574_CR35","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1161\/HYPERTENSIONAHA.111.00003","volume":"61","author":"G-H Dong","year":"2013","unstructured":"Dong G-H, Min QZ, Xaverius PK et al (2013) Association between long-term air pollution and increased blood pressure and hypertension in China. Hypertension 61:578\u2013584. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.111.00003","journal-title":"Hypertension"},{"key":"10574_CR36","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1161\/HYPERTENSIONAHA.108.123877","volume":"53","author":"JT Dvonch","year":"2009","unstructured":"Dvonch JT, Kannan S, Schulz AJ, Keeler GJ, Mentz G, House J, Benjamin A, Max P, Bard RL, Brook RD (2009) Acute effects of ambient particulate matter on blood pressure: differential effects across urban communities. Hypertens Dallas Tex 1979 53:853\u2013859. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.108.123877","journal-title":"Hypertens Dallas Tex 1979"},{"key":"10574_CR37","doi-asserted-by":"publisher","first-page":"e56636","DOI":"10.1371\/journal.pone.0056636","volume":"8","author":"F Farina","year":"2013","unstructured":"Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P (2013) Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice. PLoS One 8:e56636. https:\/\/doi.org\/10.1371\/journal.pone.0056636","journal-title":"PLoS One"},{"key":"10574_CR38","doi-asserted-by":"publisher","first-page":"766","DOI":"10.3109\/08958378.2013.847993","volume":"25","author":"MD Ferguson","year":"2013","unstructured":"Ferguson MD, Migliaccio C, Ward T (2013) Comparison of how ambient PMc and PM2.5 influence the inflammatory potential. Inhal Toxicol 25:766\u2013773. https:\/\/doi.org\/10.3109\/08958378.2013.847993","journal-title":"Inhal Toxicol"},{"key":"10574_CR39","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1007\/s12012-015-9334-y","volume":"16","author":"J Finch","year":"2016","unstructured":"Finch J, Conklin DJ (2016) Air pollution-induced vascular dysfunction: potential role of endothelin-1 (ET-1) system. Cardiovasc Toxicol 16:260\u2013275. https:\/\/doi.org\/10.1007\/s12012-015-9334-y","journal-title":"Cardiovasc Toxicol"},{"key":"10574_CR40","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/EDE.0000000000000203","volume":"26","author":"AF Fleisch","year":"2015","unstructured":"Fleisch AF, Rifas-Shiman SL, Koutrakis P, Schwartz JD, Kloog I, Melly S, Coull BA, Zanobetti A, Gillman MW, Gold DR, Oken E (2015) Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain. Epidemiology 26:43\u201350. https:\/\/doi.org\/10.1097\/EDE.0000000000000203","journal-title":"Epidemiology"},{"key":"10574_CR41","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1016\/S2542-5196(17)30020-7","volume":"1","author":"F Folino","year":"2017","unstructured":"Folino F, Buja G, Zanotto G, Marras E, Allocca G, Vaccari D, Gasparini G, Bertaglia E, Zoppo F, Calzolari V, Suh RN, Ignatiuk B, Lanera C, Benassi A, Gregori D, Iliceto S (2017) Association between air pollution and ventricular arrhythmias in high-risk patients (ARIA study): a multicentre longitudinal study. Lancet Planet Health 1:e58\u2013e64. https:\/\/doi.org\/10.1016\/S2542-5196(17)30020-7","journal-title":"Lancet Planet Health"},{"key":"10574_CR42","doi-asserted-by":"publisher","unstructured":"Fujii T, Hogg JC, Keicho N et al (2003) Adenoviral E1A modulates inflammatory mediator expression by lung epithelial cells exposed to PM10. Am J Physiol Lung Cell Mol Physiol 284. https:\/\/doi.org\/10.1152\/ajplung.00197.2002","DOI":"10.1152\/ajplung.00197.2002"},{"key":"10574_CR43","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1289\/ehp.1307725","volume":"122","author":"KB Fuks","year":"2014","unstructured":"Fuks KB, Weinmayr G, Foraster M, Dratva J, Hampel R, Houthuijs D, Oftedal B, Oudin A, Panasevich S, Penell J, Sommar JN, S\u00f8rensen M, Tiittanen P, Wolf K, Xun WW, Aguilera I, Basaga\u00f1a X, Beelen R, Bots ML, Brunekreef B, Bueno-de-Mesquita HB, Caracciolo B, Cirach M, de Faire U, de Nazelle A, Eeftens M, Elosua R, Erbel R, Forsberg B, Fratiglioni L, Gaspoz JM, Hilding A, Jula A, Korek M, Kr\u00e4mer U, K\u00fcnzli N, Lanki T, Leander K, Magnusson PKE, Marrugat J, Nieuwenhuijsen MJ, \u00d6stenson CG, Pedersen NL, Pershagen G, Phuleria HC, Probst-Hensch NM, Raaschou-Nielsen O, Schaffner E, Schikowski T, Schindler C, Schwarze PE, S\u00f8gaard AJ, Sugiri D, Swart WJR, Tsai MY, Turunen AW, Vineis P, Peters A, Hoffmann B (2014) Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Environ Health Perspect 122:896\u2013905. https:\/\/doi.org\/10.1289\/ehp.1307725","journal-title":"Environ Health Perspect"},{"key":"10574_CR44","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/1743-8977-7-34","volume":"7","author":"KM Gowdy","year":"2010","unstructured":"Gowdy KM, Krantz QT, King C, Boykin E, Jaspers I, Linak WP, Gilmour MI (2010) Role of oxidative stress on diesel-enhanced influenza infection in mice. Part Fibre Toxicol 7:34. https:\/\/doi.org\/10.1186\/1743-8977-7-34","journal-title":"Part Fibre Toxicol"},{"key":"10574_CR45","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.ntt.2016.06.008","volume":"57","author":"MH Harris","year":"2016","unstructured":"Harris MH, Gold DR, Rifas-Shiman SL, Melly SJ, Zanobetti A, Coull BA, Schwartz JD, Gryparis A, Kloog I, Koutrakis P, Bellinger DC, Belfort MB, Webster TF, White RF, Sagiv SK, Oken E (2016) Prenatal and childhood traffic-related air pollution exposure and childhood executive function and behavior. Neurotoxicol Teratol 57:60\u201370. https:\/\/doi.org\/10.1016\/j.ntt.2016.06.008","journal-title":"Neurotoxicol Teratol"},{"key":"10574_CR46","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1165\/rcmb.2002-0100OC","volume":"28","author":"KS Harrod","year":"2003","unstructured":"Harrod KS, Jaramillo RJ, Rosenberger CL, Wang SZ, Berger JA, McDonald JD, Reed MD (2003) Increased susceptibility to RSV infection by exposure to inhaled diesel engine emissions. Am J Respir Cell Mol Biol 28:451\u2013463. https:\/\/doi.org\/10.1165\/rcmb.2002-0100OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10574_CR47","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1034\/j.1399-5448.2002.30403.x","volume":"3","author":"EH Hathout","year":"2002","unstructured":"Hathout EH, Beeson WL, Nahab F, Rabadi A, Thomas W, Mace JW (2002) Role of exposure to air pollutants in the development of type 1 diabetes before and after 5 yr of age. Pediatr Diabetes 3:184\u2013188. https:\/\/doi.org\/10.1034\/j.1399-5448.2002.30403.x","journal-title":"Pediatr Diabetes"},{"key":"10574_CR48","doi-asserted-by":"publisher","first-page":"45666","DOI":"10.1038\/srep45666","volume":"7","author":"F He","year":"2017","unstructured":"He F, Liao B, Pu J, Li C, Zheng M, Huang L, Zhou Y, Zhao D, Li B, Ran P (2017) Exposure to ambient particulate matter induced COPD in a rat model and a description of the underlying mechanism. Sci Rep 7:45666. https:\/\/doi.org\/10.1038\/srep45666","journal-title":"Sci Rep"},{"key":"10574_CR49","doi-asserted-by":"crossref","first-page":"380","DOI":"10.17533\/udea.iatreia.13134","volume":"25","author":"J Hern\u00e1ndez","year":"2012","unstructured":"Hern\u00e1ndez J, Urcuqui S (2012) Activaci\u00f3n y regulaci\u00f3n del inflamasoma NLRP3 en las enfermedades infecciosas. Iatreia 25:380\u2013390","journal-title":"Iatreia"},{"key":"10574_CR50","doi-asserted-by":"publisher","first-page":"619523","DOI":"10.1155\/2013\/619523","volume":"2013","author":"K Hiraiwa","year":"2013","unstructured":"Hiraiwa K, van Eeden SF (2013) Contribution of lung macrophages to the inflammatory responses induced by exposure to air pollutants. Mediat Inflamm 2013:619523\u2013619510. https:\/\/doi.org\/10.1155\/2013\/619523","journal-title":"Mediat Inflamm"},{"key":"10574_CR51","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1165\/rcmb.2014-0158OC","volume":"52","author":"JA Hirota","year":"2015","unstructured":"Hirota JA, Gold MJ, Hiebert PR, Parkinson LG, Wee T, Smith D, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA (2015a) The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome\/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 \u03bcm. Am J Respir Cell Mol Biol 52:96\u2013105. https:\/\/doi.org\/10.1165\/rcmb.2014-0158OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10574_CR52","doi-asserted-by":"publisher","first-page":"353","DOI":"10.3109\/01902148.2015.1040528","volume":"41","author":"JA Hirota","year":"2015","unstructured":"Hirota JA, Marchant DJ, Singhera GK, Moheimani F, Dorscheid DR, Carlsten C, Sin D, Knight D (2015b) Urban particulate matter increases human airway epithelial cell IL-1\u03b2 secretion following scratch wounding and H1N1 influenza a exposure in vitro. Exp Lung Res 41:353\u2013362. https:\/\/doi.org\/10.3109\/01902148.2015.1040528","journal-title":"Exp Lung Res"},{"key":"10574_CR53","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1164\/rccm.201709-1883OC","volume":"198","author":"BD Horne","year":"2018","unstructured":"Horne BD, Joy EA, Hofmann MG, Gesteland PH, Cannon JB, Lefler JS, Blagev DP, Korgenski EK, Torosyan N, Hansen GI, Kartchner D, Pope CA III (2018) Short-term elevation of fine particulate matter air pollution and acute lower respiratory infection. Am J Respir Crit Care Med 198:759\u2013766. https:\/\/doi.org\/10.1164\/rccm.201709-1883OC","journal-title":"Am J Respir Crit Care Med"},{"key":"10574_CR54","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s12989-017-0213-5","volume":"14","author":"M Hullmann","year":"2017","unstructured":"Hullmann M, Albrecht C, van Berlo D, Gerlofs-Nijland ME, Wahle T, Boots AW, Krutmann J, Cassee FR, Bayer TA, Schins RPF (2017) Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer\u2019s disease. Part Fibre Toxicol 14:35. https:\/\/doi.org\/10.1186\/s12989-017-0213-5","journal-title":"Part Fibre Toxicol"},{"key":"10574_CR55","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1080\/09603123.2017.1278748","volume":"27","author":"S-L Hwang","year":"2017","unstructured":"Hwang S-L, Lin Y-C, Guo S-E, Chou CT, Lin CM, Chi MC (2017) Fine particulate matter on hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in southwestern Taiwan during 2006\u20132012. Int J Environ Health Res 27:95\u2013105. https:\/\/doi.org\/10.1080\/09603123.2017.1278748","journal-title":"Int J Environ Health Res"},{"key":"10574_CR56","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1093\/toxsci\/kfi141","volume":"85","author":"I Jaspers","year":"2005","unstructured":"Jaspers I, Ciencewicki JM, Zhang W, Brighton LE, Carson JL, Beck MA, Madden MC (2005) Diesel exhaust enhances influenza virus infections in respiratory epithelial cells. Toxicol Sci 85:990\u20131002. https:\/\/doi.org\/10.1093\/toxsci\/kfi141","journal-title":"Toxicol Sci"},{"key":"10574_CR57","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1182\/blood-2006-08-040352","volume":"109","author":"BJ Jenkins","year":"2007","unstructured":"Jenkins BJ, Roberts AW, Greenhill CJ, Najdovska M, Lundgren-May T, Robb L, Grail D, Ernst M (2007) Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis. Blood 109:2380\u20132388. https:\/\/doi.org\/10.1182\/blood-2006-08-040352","journal-title":"Blood"},{"key":"10574_CR58","doi-asserted-by":"publisher","first-page":"573","DOI":"10.3233\/JAD-140855","volume":"44","author":"C-R Jung","year":"2015","unstructured":"Jung C-R, Lin Y-T, Hwang B-F (2015) Ozone, particulate matter, and newly diagnosed Alzheimer\u2019s disease: a population-based cohort study in Taiwan. J Alzheimers Dis 44:573\u2013584. https:\/\/doi.org\/10.3233\/JAD-140855","journal-title":"J Alzheimers Dis"},{"key":"10574_CR59","doi-asserted-by":"crossref","unstructured":"Kelley N, Jeltema D, Duan Y, He Y (2019) The NLRP3 inflammasome: an overview of mechanisms of activation and regulation. Int J Mol Sci 20","DOI":"10.3390\/ijms20133328"},{"key":"10574_CR60","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.scitotenv.2014.01.107","volume":"481","author":"E Kim","year":"2014","unstructured":"Kim E, Park H, Hong Y-C, Ha M, Kim Y, Kim BN, Kim Y, Roh YM, Lee BE, Ryu JM, Kim BM, Ha EH (2014) Prenatal exposure to PM10 and NO2 and children\u2019s neurodevelopment from birth to 24months of age: mothers and Children\u2019s Environmental Health (MOCEH) study. Sci Total Environ 481:439\u2013445. https:\/\/doi.org\/10.1016\/j.scitotenv.2014.01.107","journal-title":"Sci Total Environ"},{"key":"10574_CR61","doi-asserted-by":"publisher","first-page":"S132","DOI":"10.1513\/AnnalsATS.201707-614MG","volume":"15","author":"C Kim","year":"2018","unstructured":"Kim C, Jary H, Mortimer K, Schweitzer KS, Curran-Everett D, Gordon S, Petrache I (2018) Effects of household air pollution in Malawi and human immunodeficiency virus status on respiratory symptoms and inflammation, injury, and repair markers. Ann Am Thorac Soc 15:S132\u2013S133. https:\/\/doi.org\/10.1513\/AnnalsATS.201707-614MG","journal-title":"Ann Am Thorac Soc"},{"key":"10574_CR62","doi-asserted-by":"publisher","first-page":"105180","DOI":"10.1016\/j.envint.2019.105180","volume":"133","author":"JS Kim","year":"2019","unstructured":"Kim JS, Chen Z, Alderete TL, Toledo-Corral C, Lurmann F, Berhane K, Gilliland FD (2019) Associations of air pollution, obesity and cardiometabolic health in young adults: the meta-AIR study. Environ Int 133:105180. https:\/\/doi.org\/10.1016\/j.envint.2019.105180","journal-title":"Environ Int"},{"key":"10574_CR63","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014944","volume":"9","author":"JB Kim","year":"2020","unstructured":"Kim JB, Prunicki M, Haddad F, Dant C, Sampath V, Patel R, Smith E, Akdis C, Balmes J, Snyder MP, Wu JC, Nadeau KC (2020) Cumulative lifetime burden of cardiovascular disease from early exposure to air pollution. J Am Heart Assoc 9:e014944. https:\/\/doi.org\/10.1161\/JAHA.119.014944","journal-title":"J Am Heart Assoc"},{"key":"10574_CR64","doi-asserted-by":"publisher","unstructured":"Ku T, Li B, Gao R et al (2017) NF-\u039aB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration. Part Fibre Toxicol 14. https:\/\/doi.org\/10.1186\/s12989-017-0215-3","DOI":"10.1186\/s12989-017-0215-3"},{"key":"10574_CR65","doi-asserted-by":"publisher","first-page":"32916","DOI":"10.1038\/srep32916","volume":"6","author":"PSJ Lakey","year":"2016","unstructured":"Lakey PSJ, Berkemeier T, Tong H, Arangio AM, Lucas K, P\u00f6schl U, Shiraiwa M (2016) Chemical exposure-response relationship between air pollutants and reactive oxygen species in the human respiratory tract. Sci Rep 6:32916. https:\/\/doi.org\/10.1038\/srep32916","journal-title":"Sci Rep"},{"key":"10574_CR66","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1161\/HYPERTENSIONAHA.109.135947","volume":"54","author":"JP Langrish","year":"2009","unstructured":"Langrish JP, Lundback M, Mills NL et al (2009) Contribution of Endothelin 1 to the vascular effects of diesel exhaust inhalation in humans. Hypertension 54:910\u2013915. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.109.135947","journal-title":"Hypertension"},{"key":"10574_CR67","doi-asserted-by":"publisher","first-page":"71","DOI":"10.5487\/TR.2014.30.2.071","volume":"30","author":"B-J Lee","year":"2014","unstructured":"Lee B-J, Kim B, Lee K (2014) Air pollution exposure and cardiovascular disease. Toxicol Res 30:71\u201375. https:\/\/doi.org\/10.5487\/TR.2014.30.2.071","journal-title":"Toxicol Res"},{"key":"10574_CR68","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.aogh.2015.08.006","volume":"81","author":"A Lee","year":"2015","unstructured":"Lee A, Kinney P, Chillrud S, Jack D (2015) A systematic review of innate Immunomodulatory effects of household air pollution secondary to the burning of biomass fuels. Ann Glob Health 81:368. https:\/\/doi.org\/10.1016\/j.aogh.2015.08.006","journal-title":"Ann Glob Health"},{"key":"10574_CR69","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/1742-2094-8-105","volume":"8","author":"S Levesque","year":"2011","unstructured":"Levesque S, Surace MJ, McDonald J, Block ML (2011) Air pollution & the brain: subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease. J Neuroinflammation 8:105. https:\/\/doi.org\/10.1186\/1742-2094-8-105","journal-title":"J Neuroinflammation"},{"key":"10574_CR70","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1111\/jnc.12231","volume":"125","author":"S Levesque","year":"2013","unstructured":"Levesque S, Taetzsch T, Lull ME, Johnson JA, McGraw C, Block ML (2013) The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function. J Neurochem 125:756\u2013765. https:\/\/doi.org\/10.1111\/jnc.12231","journal-title":"J Neurochem"},{"key":"10574_CR71","doi-asserted-by":"publisher","first-page":"L374","DOI":"10.1152\/ajplung.00115.2010","volume":"299","author":"N Li","year":"2010","unstructured":"Li N, Harkema JR, Lewandowski RP, Wang M, Bramble LA, Gookin GR, Ning Z, Kleinman MT, Sioutas C, Nel AE (2010) Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares. Am J Physiol Lung Cell Mol Physiol 299:L374\u2013L383. https:\/\/doi.org\/10.1152\/ajplung.00115.2010","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10574_CR72","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1378\/chest.15-0513","volume":"149","author":"M-H Li","year":"2016","unstructured":"Li M-H, Fan L-C, Mao B, Yang JW, Choi AMK, Cao WJ, Xu JF (2016) Short-term exposure to ambient fine particulate matter increases hospitalizations and mortality in COPD. Chest 149:447\u2013458. https:\/\/doi.org\/10.1378\/chest.15-0513","journal-title":"Chest"},{"key":"10574_CR73","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1161\/CIRCULATIONAHA.116.026796","volume":"136","author":"H Li","year":"2017","unstructured":"Li H, Cai J, Chen R, Zhao Z, Ying Z, Wang L, Chen J, Hao K, Kinney PL, Chen H, Kan H (2017) Particulate matter exposure and stress hormone levels: a randomized, double-blind, crossover trial of air purification. Circulation 136:618\u2013627. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.116.026796","journal-title":"Circulation"},{"key":"10574_CR74","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1039\/c8tx00093j","volume":"7","author":"Q Li","year":"2018","unstructured":"Li Q, Zheng J, Xu S, Zhang J, Cao Y, Qin Z, Liu X, Jiang C (2018) The neurotoxicity induced by PM2.5 might be strongly related to changes of the hippocampal tissue structure and neurotransmitter levels. Toxicol Res 7:1144\u20131152. https:\/\/doi.org\/10.1039\/c8tx00093j","journal-title":"Toxicol Res"},{"key":"10574_CR75","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1016\/S0140-6736(12)61766-8","volume":"380","author":"SS Lim","year":"2012","unstructured":"Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, AlMazroa MA, Amann M, Anderson HR, Andrews KG, Aryee M, Atkinson C, Bacchus LJ, Bahalim AN, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell ML, Blore JD, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce NG, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett RT, Byers TE, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen JS, Cheng ATA, Child JC, Cohen A, Colson KE, Cowie BC, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Des Jarlais DC, Devries K, Dherani M, Ding EL, Dorsey ER, Driscoll T, Edmond K, Ali SE, Engell RE, Erwin PJ, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane MM, Flaxman S, Fowkes FGR, Freedman G, Freeman MK, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez HR, Hall W, Hoek HW, Hogan A, Hosgood HD III, Hoy D, Hu H, Hubbell BJ, Hutchings SJ, Ibeanusi SE, Jacklyn GL, Jasrasaria R, Jonas JB, Kan H, Kanis JA, Kassebaum N, Kawakami N, Khang YH, Khatibzadeh S, Khoo JP, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher JL, Leigh J, Li Y, Lin JK, Lipshultz SE, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Memish ZA, Mensah GA, Merriman TR, Micha R, Michaud C, Mishra V, Hanafiah KM, Mokdad AA, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson PK, Nolla JM, Norman R, Olives C, Omer SB, Orchard J, Osborne R, Ostro B, Page A, Pandey KD, Parry CDH, Passmore E, Patra J, Pearce N, Pelizzari PM, Petzold M, Phillips MR, Pope D, Pope CA III, Powles J, Rao M, Razavi H, Rehfuess EA, Rehm JT, Ritz B, Rivara FP, Roberts T, Robinson C, Rodriguez-Portales JA, Romieu I, Room R, Rosenfeld LC, Roy A, Rushton L, Salomon JA, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh GM, Sleet DA, Smith E, Smith KR, Stapelberg NJC, Steenland K, St\u00f6ckl H, Stovner LJ, Straif K, Straney L, Thurston GD, Tran JH, van Dingenen R, van Donkelaar A, Veerman JL, Vijayakumar L, Weintraub R, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams W, Wilson N, Woolf AD, Yip P, Zielinski JM, Lopez AD, Murray CJL, Ezzati M (2012) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2224\u20132260. https:\/\/doi.org\/10.1016\/S0140-6736(12)61766-8","journal-title":"Lancet"},{"key":"10574_CR76","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/jnc.13135","volume":"134","author":"F Liu","year":"2015","unstructured":"Liu F, Huang Y, Zhang F, Chen Q, Wu B, Rui W, Zheng JC, Ding W (2015) Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. J Neurochem 134:315\u2013326. https:\/\/doi.org\/10.1111\/jnc.13135","journal-title":"J Neurochem"},{"key":"10574_CR77","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1111\/pace.13500","volume":"41","author":"X Liu","year":"2018","unstructured":"Liu X, Kong D, Liu Y, Fu J, Gao P, Chen T, Fang Q, Cheng K', Fan Z (2018) Effects of the short-term exposure to ambient air pollution on atrial fibrillation. Pacing Clin Electrophysiol 41:1441\u20131446. https:\/\/doi.org\/10.1111\/pace.13500","journal-title":"Pacing Clin Electrophysiol"},{"key":"10574_CR78","doi-asserted-by":"publisher","first-page":"5708","DOI":"10.1038\/s41598-018-23885-3","volume":"8","author":"JY Ljubimova","year":"2018","unstructured":"Ljubimova JY, Braubach O, Patil R et al (2018) Coarse particulate matter (PM2.5\u201310) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains. Sci Rep 8:5708. https:\/\/doi.org\/10.1038\/s41598-018-23885-3","journal-title":"Sci Rep"},{"key":"10574_CR79","doi-asserted-by":"publisher","first-page":"2348","DOI":"10.1056\/NEJMoa071535","volume":"357","author":"J McCreanor","year":"2007","unstructured":"McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han IK, Ohman-Strickland P, Chung KF, Zhang J (2007) Respiratory effects of exposure to diesel traffic in persons with asthma. N Engl J Med 357:2348\u20132358. https:\/\/doi.org\/10.1056\/NEJMoa071535","journal-title":"N Engl J Med"},{"key":"10574_CR80","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.envint.2018.11.001","volume":"122","author":"LA McGuinn","year":"2019","unstructured":"McGuinn LA, Schneider A, McGarrah RW et al (2019) Association of long-term PM 2.5 exposure with traditional and novel lipid measures related to cardiovascular disease risk. Environ Int 122:193\u2013200. https:\/\/doi.org\/10.1016\/j.envint.2018.11.001","journal-title":"Environ Int"},{"key":"10574_CR81","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1186\/s12931-016-0392-x","volume":"17","author":"YA Mebratu","year":"2016","unstructured":"Mebratu YA, Smith KR, Agga GE, Tesfaigzi Y (2016) Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza a or respiratory syncytial viruses. Respir Res 17:75. https:\/\/doi.org\/10.1186\/s12931-016-0392-x","journal-title":"Respir Res"},{"key":"10574_CR82","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3109\/08958378.2012.756086","volume":"25","author":"CT Migliaccio","year":"2013","unstructured":"Migliaccio CT, Kobos E, King QO, Porter V, Jessop F, Ward T (2013) Adverse effects of wood smoke PM2.5 exposure on macrophage functions. Inhal Toxicol 25:67\u201376. https:\/\/doi.org\/10.3109\/08958378.2012.756086","journal-title":"Inhal Toxicol"},{"key":"10574_CR83","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.taap.2011.09.007","volume":"257","author":"R Miyata","year":"2011","unstructured":"Miyata R, van Eeden SF (2011) The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter. Toxicol Appl Pharmacol 257:209\u2013226. https:\/\/doi.org\/10.1016\/j.taap.2011.09.007","journal-title":"Toxicol Appl Pharmacol"},{"key":"10574_CR84","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.envres.2013.01.006","volume":"123","author":"Z Mobasher","year":"2013","unstructured":"Mobasher Z, Salam MT, Goodwin TM, Lurmann F, Ingles SA, Wilson ML (2013) Associations between ambient air pollution and hypertensive disorders of pregnancy. Environ Res 123:9\u201316. https:\/\/doi.org\/10.1016\/j.envres.2013.01.006","journal-title":"Environ Res"},{"key":"10574_CR85","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.2147\/COPD.S192047","volume":"14","author":"JA Morantes-Caballero","year":"2019","unstructured":"Morantes-Caballero JA, Alberto H, Rodriguez F (2019) Effects of air pollution on acute exacerbation of chronic obstructive pulmonary disease: a descriptive retrospective study (pol-AECOPD). Int J COPD 14:1549\u20131557. https:\/\/doi.org\/10.2147\/COPD.S192047","journal-title":"Int J COPD"},{"key":"10574_CR86","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.ijcard.2016.03.062","volume":"212","author":"T Muka","year":"2016","unstructured":"Muka T, Koromani F, Portilla E, O'Connor A, Bramer WM, Troup J, Chowdhury R, Dehghan A, Franco OH (2016) The role of epigenetic modifications in cardiovascular disease: a systematic review. Int J Cardiol 212:174\u2013183. https:\/\/doi.org\/10.1016\/j.ijcard.2016.03.062","journal-title":"Int J Cardiol"},{"key":"10574_CR87","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/J.IMMUNI.2013.05.016","volume":"38","author":"R Mu\u00f1oz-Planillo","year":"2013","unstructured":"Mu\u00f1oz-Planillo R, Kuffa P, Mart\u00ednez-Col\u00f3n G, Smith BL, Rajendiran TM, N\u00fa\u00f1ez G (2013) K+ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38:1142\u20131153. https:\/\/doi.org\/10.1016\/J.IMMUNI.2013.05.016","journal-title":"Immunity"},{"key":"10574_CR88","doi-asserted-by":"publisher","first-page":"3543","DOI":"10.1093\/eurheartj\/ehy481","volume":"39","author":"T M\u00fcnzel","year":"2018","unstructured":"M\u00fcnzel T, Gori T, Al-Kindi S et al (2018) Effects of gaseous and solid constituents of air pollution on endothelial function. Eur Heart J 39:3543\u20133550. https:\/\/doi.org\/10.1093\/eurheartj\/ehy481","journal-title":"Eur Heart J"},{"key":"10574_CR89","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1001\/jama.2012.126","volume":"307","author":"H Mustafic","year":"2012","unstructured":"Mustafic H, Jabre P, Caussin C et al (2012) Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA 307:713\u2013721. https:\/\/doi.org\/10.1001\/jama.2012.126","journal-title":"JAMA"},{"key":"10574_CR90","doi-asserted-by":"publisher","first-page":"2952","DOI":"10.1172\/JCI30639","volume":"117","author":"GM Mutlu","year":"2007","unstructured":"Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GRS (2007) Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest 117:2952\u20132961. https:\/\/doi.org\/10.1172\/JCI30639","journal-title":"J Clin Invest"},{"key":"10574_CR91","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/J.TOX.2011.03.018","volume":"285","author":"A Nemmar","year":"2011","unstructured":"Nemmar A, Zia S, Subramaniyan D, Fahim MA, Ali BH (2011) Exacerbation of thrombotic events by diesel exhaust particle in mouse model of hypertension. Toxicology 285:39\u201345. https:\/\/doi.org\/10.1016\/J.TOX.2011.03.018","journal-title":"Toxicology"},{"key":"10574_CR92","doi-asserted-by":"publisher","first-page":"e368","DOI":"10.1016\/S2542-5196(17)30166-3","volume":"1","author":"K Newell","year":"2017","unstructured":"Newell K, Kartsonaki C, Lam KBH, Kurmi OP (2017) Cardiorespiratory health effects of particulate ambient air pollution exposure in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Planet Health 1:e368\u2013e380. https:\/\/doi.org\/10.1016\/S2542-5196(17)30166-3","journal-title":"Lancet Planet Health"},{"key":"10574_CR93","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1743-8977-5-1","volume":"5","author":"TR Nurkiewicz","year":"2008","unstructured":"Nurkiewicz TR, Porter DW, Hubbs AF, Cumpston JL, Chen BT, Frazer DG, Castranova V (2008) Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction. Part Fibre Toxicol 5:1. https:\/\/doi.org\/10.1186\/1743-8977-5-1","journal-title":"Part Fibre Toxicol"},{"key":"10574_CR94","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.tox.2009.01.028","volume":"259","author":"J \u00d8vrevik","year":"2009","unstructured":"\u00d8vrevik J, L\u00e5g M, Holme JA, Schwarze PE, Refsnes M (2009) Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution. Toxicology 259:46\u201353. https:\/\/doi.org\/10.1016\/j.tox.2009.01.028","journal-title":"Toxicology"},{"key":"10574_CR95","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.envres.2010.11.001","volume":"111","author":"EJ Park","year":"2011","unstructured":"Park EJ, Roh J, Kim Y, Park K, Kim DS, Yu SD (2011) PM 2.5 collected in a residential area induced Th1-type inflammatory responses with oxidative stress in mice. Environ Res 111:348\u2013355. https:\/\/doi.org\/10.1016\/j.envres.2010.11.001","journal-title":"Environ Res"},{"key":"10574_CR96","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1161\/HYPERTENSIONAHA.114.03545","volume":"64","author":"M Pedersen","year":"2014","unstructured":"Pedersen M, Stayner L, Slama R, S\u00f8rensen M, Figueras F, Nieuwenhuijsen MJ, Raaschou-Nielsen O, Dadvand P (2014) Ambient air pollution and pregnancy-induced hypertensive disorders: a systematic review and meta-analysis. Hypertension 64:494\u2013500. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.114.03545","journal-title":"Hypertension"},{"key":"10574_CR97","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.chemosphere.2017.08.076","volume":"188","author":"MS Peixoto","year":"2017","unstructured":"Peixoto MS, de Oliveira Galv\u00e3o MF, Batistuzzo de Medeiros SR (2017) Cell death pathways of particulate matter toxicity. Chemosphere 188:32\u201348. https:\/\/doi.org\/10.1016\/j.chemosphere.2017.08.076","journal-title":"Chemosphere"},{"key":"10574_CR98","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1289\/EHP183","volume":"124","author":"C Peng","year":"2016","unstructured":"Peng C, Bind M-AC, Colicino E, Kloog I, Byun HM, Cantone L, Trevisi L, Zhong J, Brennan K, Dereix AE, Vokonas PS, Coull BA, Schwartz JD, Baccarelli AA (2016) Particulate air pollution and fasting blood glucose in nondiabetic individuals: associations and epigenetic mediation in the normative aging study, 2000\u20132011. Environ Health Perspect 124:1715\u20131721. https:\/\/doi.org\/10.1289\/EHP183","journal-title":"Environ Health Perspect"},{"key":"10574_CR99","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1161\/01.CIR.103.23.2810","volume":"103","author":"A Peters","year":"2001","unstructured":"Peters A, Dockery DW, Muller JE, Mittleman MA (2001) Increased particulate air pollution and the triggering of myocardial infarction. Circulation 103:2810\u20132815. https:\/\/doi.org\/10.1161\/01.CIR.103.23.2810","journal-title":"Circulation"},{"key":"10574_CR100","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1161\/CIRCRESAHA.116.309279","volume":"119","author":"CA Pope","year":"2016","unstructured":"Pope CA, Bhatnagar A, McCracken JP et al (2016) Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation. Circ Res 119:1204\u20131214. https:\/\/doi.org\/10.1161\/CIRCRESAHA.116.309279","journal-title":"Circ Res"},{"key":"10574_CR101","doi-asserted-by":"publisher","first-page":"h1111","DOI":"10.1136\/bmj.h1111","volume":"350","author":"MC Power","year":"2015","unstructured":"Power MC, Kioumourtzoglou M-A, Hart JE, Okereke OI, Laden F, Weisskopf MG (2015) The relation between past exposure to fine particulate air pollution and prevalent anxiety: observational cohort study. BMJ 350:h1111. https:\/\/doi.org\/10.1136\/bmj.h1111","journal-title":"BMJ"},{"key":"10574_CR102","doi-asserted-by":"publisher","first-page":"3331","DOI":"10.4049\/jimmunol.1004062","volume":"187","author":"S Provoost","year":"2011","unstructured":"Provoost S, Maes T, Pauwels NS, vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Tournoy KG (2011) NLRP3\/caspase-1-independent IL-1 production mediates diesel exhaust particle-induced pulmonary inflammation. J Immunol 187:3331\u20133337. https:\/\/doi.org\/10.4049\/jimmunol.1004062","journal-title":"J Immunol"},{"key":"10574_CR103","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1289\/EHP494","volume":"125","author":"VC Pun","year":"2017","unstructured":"Pun VC, Manjourides J, Suh H (2017) Association of ambient air pollution with depressive and anxiety symptoms in older adults: results from the NSHAP study. Environ Health Perspect 125:342\u2013348. https:\/\/doi.org\/10.1289\/EHP494","journal-title":"Environ Health Perspect"},{"key":"10574_CR104","doi-asserted-by":"publisher","unstructured":"Rebuli ME, Speen AM, Martin EM et al (2019) Wood smoke exposure alters human inflammatory responses to viral infection in a sex-specific manner: a randomized, placebo-controlled study. Am J Respir Crit Care Med:rccm.201807-1287OC. https:\/\/doi.org\/10.1164\/rccm.201807-1287OC","DOI":"10.1164\/rccm.201807-1287OC"},{"key":"10574_CR105","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.mrfmmm.2005.06.012","volume":"592","author":"L Risom","year":"2005","unstructured":"Risom L, M\u00f8ller P, Loft S (2005) Oxidative stress-induced DNA damage by particulate air pollution. Mutat Res Mol Mech Mutagen 592:119\u2013137. https:\/\/doi.org\/10.1016\/j.mrfmmm.2005.06.012","journal-title":"Mutat Res Mol Mech Mutagen"},{"key":"10574_CR106","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.1128\/IAI.03018-14","volume":"83","author":"CE Rivas-Santiago","year":"2015","unstructured":"Rivas-Santiago CE, Sarkar S, Cantarella P et al (2015) Air pollution particulate matter alters antimycobacterial respiratory epithelium innate immunity. Infect Immun 83:2507\u20132517. https:\/\/doi.org\/10.1128\/IAI.03018-14","journal-title":"Infect Immun"},{"key":"10574_CR107","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.neuro.2016.08.006","volume":"56","author":"PJ Roqu\u00e9","year":"2016","unstructured":"Roqu\u00e9 PJ, Dao K, Costa LG (2016) Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms. NeuroToxicology 56:204\u2013214. https:\/\/doi.org\/10.1016\/j.neuro.2016.08.006","journal-title":"NeuroToxicology"},{"key":"10574_CR108","doi-asserted-by":"crossref","unstructured":"Sachdeva K, Do DC, Zhang Y, Hu X, Chen J, Gao P (2019) Environmental exposures and asthma development: autophagy, mitophagy, and cellular senescence. Front Immunol 10","DOI":"10.3389\/fimmu.2019.02787"},{"key":"10574_CR109","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/s12989-016-0162-4","volume":"13","author":"M Sayan","year":"2015","unstructured":"Sayan M, Mossman BT (2015) The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases. Part Fibre Toxicol 13:51. https:\/\/doi.org\/10.1186\/s12989-016-0162-4","journal-title":"Part Fibre Toxicol"},{"key":"10574_CR110","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/J.ENVRES.2007.05.003","volume":"106","author":"C S\u00e9gala","year":"2008","unstructured":"S\u00e9gala C, Poizeau D, Mesbah M, Willems S, Maidenberg M (2008) Winter air pollution and infant bronchiolitis in Paris. Environ Res 106:96\u2013100. https:\/\/doi.org\/10.1016\/J.ENVRES.2007.05.003","journal-title":"Environ Res"},{"key":"10574_CR111","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1007\/s00431-010-1379-0","volume":"170","author":"S Siddique","year":"2011","unstructured":"Siddique S, Banerjee M, Ray MR, Lahiri T (2011) Attention-deficit hyperactivity disorder in children chronically exposed to high level of vehicular pollution. Eur J Pediatr 170:923\u2013929. https:\/\/doi.org\/10.1007\/s00431-010-1379-0","journal-title":"Eur J Pediatr"},{"key":"10574_CR112","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.taap.2007.04.014","volume":"223","author":"S Sigaud","year":"2007","unstructured":"Sigaud S, Goldsmith CAW, Zhou H, Yang Z, Fedulov A, Imrich A, Kobzik L (2007) Air pollution particles diminish bacterial clearance in the primed lungs of mice. Toxicol Appl Pharmacol 223:1\u20139. https:\/\/doi.org\/10.1016\/j.taap.2007.04.014","journal-title":"Toxicol Appl Pharmacol"},{"key":"10574_CR113","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ecoenv.2018.05.083","volume":"161","author":"B Sun","year":"2018","unstructured":"Sun B, Shi Y, Yang X, Zhao T, Duan J, Sun Z (2018a) DNA methylation: a critical epigenetic mechanism underlying the detrimental effects of airborne particulate matter. Ecotoxicol Environ Saf 161:173\u2013183. https:\/\/doi.org\/10.1016\/j.ecoenv.2018.05.083","journal-title":"Ecotoxicol Environ Saf"},{"key":"10574_CR114","doi-asserted-by":"publisher","unstructured":"Sun Y, Wang Y, Yuan S et al (2018b) Exposure to PM2.5 via vascular endothelial growth factor relationship: meta-analysis. PLoS ONE 13. https:\/\/doi.org\/10.1371\/journal.pone.0198813","DOI":"10.1371\/journal.pone.0198813"},{"key":"10574_CR115","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/S0735-1097(02)01715-1","volume":"39","author":"T Suwa","year":"2002","unstructured":"Suwa T, Hogg JC, Quinlan KB, Ohgami A, Vincent R, van Eeden SF (2002) Particulate air pollution induces progression of atherosclerosis. J Am Coll Cardiol 39:935\u2013942. https:\/\/doi.org\/10.1016\/S0735-1097(02)01715-1","journal-title":"J Am Coll Cardiol"},{"key":"10574_CR116","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1289\/ehp.11898","volume":"117","author":"L Tarantini","year":"2009","unstructured":"Tarantini L, Bonzini M, Apostoli P, Pegoraro V, Bollati V, Marinelli B, Cantone L, Rizzo G, Hou L, Schwartz J, Bertazzi PA, Baccarelli A (2009) Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation. Environ Health Perspect 117:217\u2013222. https:\/\/doi.org\/10.1289\/ehp.11898","journal-title":"Environ Health Perspect"},{"key":"10574_CR117","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1097\/JOM.0000000000001277","volume":"60","author":"JE Thompson","year":"2018","unstructured":"Thompson JE (2018) Airborne particulate matter: human exposure and health effects. J Occup Environ Med 60:392\u2013423. https:\/\/doi.org\/10.1097\/JOM.0000000000001277","journal-title":"J Occup Environ Med"},{"key":"10574_CR118","doi-asserted-by":"publisher","first-page":"6015","DOI":"10.3390\/ijerph10116015","volume":"10","author":"S-S Tsai","year":"2013","unstructured":"Tsai S-S, Chang C-C, Yang C-Y (2013) Fine particulate air pollution and hospital admissions for chronic obstructive pulmonary disease: a case-crossover study in Taipei. Int J Environ Res Public Health 10:6015\u20136026. https:\/\/doi.org\/10.3390\/ijerph10116015","journal-title":"Int J Environ Res Public Health"},{"key":"10574_CR119","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1164\/rccm.201106-1011OC","volume":"184","author":"MC Turner","year":"2011","unstructured":"Turner MC, Krewski D, Pope CA et al (2011) Long-term ambient fine particulate matter air pollution and lung cancer in a large cohort of never-smokers. Am J Respir Crit Care Med 184:1374\u20131381. https:\/\/doi.org\/10.1164\/rccm.201106-1011OC","journal-title":"Am J Respir Crit Care Med"},{"key":"10574_CR120","doi-asserted-by":"publisher","first-page":"865","DOI":"10.3904\/kjim.2016.033","volume":"32","author":"S-T Uh","year":"2017","unstructured":"Uh S-T, Koo SM, Kim Y, Kim K, Park S, Jang AS, Kim D, Kim YH, Park CS (2017) The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line. Korean J Intern Med 32:865\u2013874. https:\/\/doi.org\/10.3904\/kjim.2016.033","journal-title":"Korean J Intern Med"},{"key":"10574_CR121","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/875723","volume":"2015","author":"S Vandini","year":"2015","unstructured":"Vandini S, Bottau P, Faldella G, Lanari M (2015) Immunological, viral, environmental, and individual factors modulating lung immune response to respiratory syncytial virus. Biomed Res Int 2015:1\u20137. https:\/\/doi.org\/10.1155\/2015\/875723","journal-title":"Biomed Res Int"},{"key":"10574_CR122","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/j.ijheh.2017.06.009","volume":"220","author":"C Vert","year":"2017","unstructured":"Vert C, S\u00e1nchez-Benavides G, Mart\u00ednez D, Gotsens X, Gramunt N, Cirach M, Molinuevo JL, Sunyer J, Nieuwenhuijsen MJ, Crous-Bou M, Gascon M (2017) Effect of long-term exposure to air pollution on anxiety and depression in adults: a cross-sectional study. Int J Hyg Environ Health 220:1074\u20131080. https:\/\/doi.org\/10.1016\/j.ijheh.2017.06.009","journal-title":"Int J Hyg Environ Health"},{"key":"10574_CR123","doi-asserted-by":"publisher","first-page":"44256","DOI":"10.1038\/srep44256","volume":"7","author":"H Wang","year":"2017","unstructured":"Wang H, Song L, Ju W et al (2017) The acute airway inflammation induced by PM2.5 exposure and the treatment of essential oils in Balb\/c mice. Sci Rep 7:44256. https:\/\/doi.org\/10.1038\/srep44256","journal-title":"Sci Rep"},{"key":"10574_CR124","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/6287932","volume":"2018","author":"SH Woo","year":"2018","unstructured":"Woo SH, Lee SM, Park KC, Park GN, Cho B, Kim I, Kim J, Hong S (2018) Effects of fine particulate matter on Pseudomonas aeruginosa adhesion and biofilm formation in vitro. Biomed Res Int 2018:1\u201310. https:\/\/doi.org\/10.1155\/2018\/6287932","journal-title":"Biomed Res Int"},{"key":"10574_CR125","volume-title":"Air quality guidelines global update 2005","author":"World Health Organization","year":"2006","unstructured":"World Health Organization (2006) Air quality guidelines global update 2005. World Health Organization, Copenhagen"},{"key":"10574_CR126","volume-title":"HealtH effects of particulate matter, WHO","author":"World Health Organization","year":"2013","unstructured":"World Health Organization (2013) HealtH effects of particulate matter, WHO. World Health Organization, Copenhagen"},{"key":"10574_CR127","unstructured":"World Health Organization (2014) 7 million premature deaths annually linked to air pollution. In: World Health Organ. http:\/\/www.who.int\/mediacentre\/news\/releases\/2014\/air-pollution\/en\/"},{"key":"10574_CR128","unstructured":"World Health Organization (2016) Ambient (outdoor) air quality and health. In: World Health Organ. http:\/\/www.who.int\/en\/news-room\/fact-sheets\/detail\/ambient-(outdoor)-air-quality-and-health"},{"key":"10574_CR129","doi-asserted-by":"publisher","first-page":"E69","DOI":"10.3978\/j.issn.2072-1439.2016.01.19","volume":"8","author":"Y-F Xing","year":"2016","unstructured":"Xing Y-F, Xu Y-H, Shi M-H, Lian Y-X (2016) The impact of PM2.5 on the human respiratory system. J Thorac Dis 8:E69\u2013E74. https:\/\/doi.org\/10.3978\/j.issn.2072-1439.2016.01.19","journal-title":"J Thorac Dis"},{"key":"10574_CR130","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.envpol.2016.09.065","volume":"220","author":"Q Xu","year":"2017","unstructured":"Xu Q, Wang S, Guo Y, Wang C, Huang F, Li X, Gao Q, Wu L, Tao L, Guo J, Wang W, Guo X (2017) Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing, China. Environ Pollut 220:317\u2013327. https:\/\/doi.org\/10.1016\/j.envpol.2016.09.065","journal-title":"Environ Pollut"},{"key":"10574_CR131","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1186\/s40064-016-3734-8","volume":"5","author":"B Yang","year":"2016","unstructured":"Yang B, Chen D, Zhao H, Xiao C (2016) The effects for PM2.5 exposure on non-small-cell lung cancer induced motility and proliferation. SpringerPlus 5:2059. https:\/\/doi.org\/10.1186\/s40064-016-3734-8","journal-title":"SpringerPlus"},{"key":"10574_CR132","first-page":"1355","volume":"20","author":"S Yang","year":"2019","unstructured":"Yang S, Lee S-P, Park J-B, Lee H, Kang S-H, Lee S-E, Kim JB, Choi S-Y, Kim Y-J, Chang H-J (2019) PM2.5 concentration in the ambient air is a risk factor for the development of high-risk coronary plaques. Eur Heart J 20:1355\u20131364","journal-title":"Eur Heart J"},{"key":"10574_CR133","doi-asserted-by":"crossref","unstructured":"Yang L, Li C, Tang X (2020) The impact of PM2.5 on the host defense of respiratory system. Front Cell Dev Biol 8","DOI":"10.3389\/fcell.2020.00091"},{"key":"10574_CR134","doi-asserted-by":"publisher","first-page":"H1540","DOI":"10.1152\/ajpheart.01270.2008","volume":"296","author":"Z Ying","year":"2009","unstructured":"Ying Z, Yue P, Xu X, Zhong M, Sun Q, Mikolaj M, Wang A, Brook RD, Chen LC, Rajagopalan S (2009) Air pollution and cardiac remodeling: a role for RhoA\/Rho-kinase. Am J Physiol-Heart Circ Physiol 296:H1540\u2013H1550. https:\/\/doi.org\/10.1152\/ajpheart.01270.2008","journal-title":"Am J Physiol-Heart Circ Physiol"},{"key":"10574_CR135","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/1476-069X-13-38","volume":"13","author":"A Zanobetti","year":"2014","unstructured":"Zanobetti A, Dominici F, Wang Y, Schwartz JD (2014) A national case-crossover analysis of the short-term effect of PM2.5 on hospitalizations and mortality in subjects with diabetes and neurological disorders. Environ Health 13:38. https:\/\/doi.org\/10.1186\/1476-069X-13-38","journal-title":"Environ Health"},{"key":"10574_CR136","doi-asserted-by":"publisher","first-page":"8679","DOI":"10.1038\/s41598-017-08984-x","volume":"7","author":"Z Zhang","year":"2017","unstructured":"Zhang Z, Hong Y, Liu N (2017) Association of ambient particulate matter 2.5 with intensive care unit admission due to pneumonia: a distributed lag non-linear model. Sci Rep 7:8679. https:\/\/doi.org\/10.1038\/s41598-017-08984-x","journal-title":"Sci Rep"},{"key":"10574_CR137","doi-asserted-by":"publisher","first-page":"827","DOI":"10.3389\/fneur.2018.00827","volume":"9","author":"R Zhang","year":"2018","unstructured":"Zhang R, Liu G, Jiang Y, Li G, Pan Y, Wang Y, Wei Z, Wang J, Wang Y (2018) Acute effects of particulate air pollution on ischemic stroke and hemorrhagic stroke mortality. Front Neurol 9:827. https:\/\/doi.org\/10.3389\/fneur.2018.00827","journal-title":"Front Neurol"},{"key":"10574_CR138","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.envint.2019.04.036","volume":"128","author":"Z Zhang","year":"2019","unstructured":"Zhang Z, Dong B, Li S, Chen G, Yang Z, Dong Y, Wang Z, Ma J, Guo Y (2019) Exposure to ambient particulate matter air pollution, blood pressure and hypertension in children and adolescents: a national cross-sectional study in China. Environ Int 128:103\u2013108. https:\/\/doi.org\/10.1016\/j.envint.2019.04.036","journal-title":"Environ Int"},{"key":"10574_CR139","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.tox.2014.09.006","volume":"325","author":"H Zhao","year":"2014","unstructured":"Zhao H, Li W, Gao Y, Li J, Wang H (2014) Exposure to particular matter increases susceptibility to respiratory Staphylococcus aureus infection in rats via reducing pulmonary natural killer cells. Toxicology 325:180\u2013188. https:\/\/doi.org\/10.1016\/j.tox.2014.09.006","journal-title":"Toxicology"},{"key":"10574_CR140","first-page":"836","volume":"36","author":"D Zheng","year":"2013","unstructured":"Zheng D, Fei-yan D, Ya-dong Y et al (2013) Effects of PM2.5 exposure on Klebsiella Pneumoniae clearance in the lungs of rats. Chin J Tuberc Respir Dis 36:836\u2013840","journal-title":"Chin J Tuberc Respir Dis"},{"key":"10574_CR141","doi-asserted-by":"publisher","unstructured":"Zhong J, Colicino E, Lin X et al (2015a) Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of toll-like receptor 2 and dietary flavonoid intake. J Am Heart Assoc 4. https:\/\/doi.org\/10.1161\/JAHA.114.001423","DOI":"10.1161\/JAHA.114.001423"},{"key":"10574_CR142","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1161\/HYPERTENSIONAHA.115.05342","volume":"66","author":"J Zhong","year":"2015","unstructured":"Zhong J, Urch B, Speck M, Coull BA, Koutrakis P, Thorne PS, Scott J, Liu L, Brook RD, Behbod B, Gibson H, Silverman F, Mittleman MA, Baccarelli AA, Gold DR (2015b) Endotoxin and \u03b2-1,3-d-glucan in concentrated ambient particles induce rapid increase in blood pressure in controlled human exposures. Hypertension 66:509\u2013516. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.115.05342","journal-title":"Hypertension"},{"key":"10574_CR143","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1165\/rcmb.2006-0293OC","volume":"36","author":"H Zhou","year":"2007","unstructured":"Zhou H, Kobzik L (2007) Effect of concentrated ambient particles on macrophage phagocytosis and killing of Streptococcus pneumoniae. Am J Respir Cell Mol Biol 36:460\u2013465. https:\/\/doi.org\/10.1165\/rcmb.2006-0293OC","journal-title":"Am J Respir Cell Mol Biol"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-10574-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-020-10574-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-10574-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T13:26:06Z","timestamp":1696598766000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-020-10574-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":143,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10574"],"URL":"https:\/\/doi.org\/10.1007\/s11356-020-10574-w","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]},"assertion":[{"value":"24 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they do not have a conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The funders had no role in the study design, data collection, and analysis, decision to publish, or preparation of the manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}