{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:24:18Z","timestamp":1776813858676,"version":"3.51.2"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"16","license":[{"start":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T00:00:00Z","timestamp":1609891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T00:00:00Z","timestamp":1609891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s11356-020-11279-w","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T07:03:09Z","timestamp":1609916589000},"page":"19768-19782","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Adiantum capillus-veneris Linn protects female reproductive system against carbendazim toxicity in rats: immunohistochemical, histopathological, and pathophysiological studies"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8020-6863","authenticated-orcid":false,"given":"Abd El-Nasser A.","family":"Madboli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed M.","family":"Seif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,1,6]]},"reference":[{"key":"11279_CR1","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.etap.2013.01.010","volume":"35","author":"IA Adedara","year":"2013","unstructured":"Adedara IA, Vaithinathan S, Jubendradass R, Mathur PP, Farombi EO (2013) Kolaviron prevents carbendazim-induced steroidogenic dysfunction and apoptosis in testes of rats. Environ Toxicol Pharmacol 35:444\u2013453. https:\/\/doi.org\/10.1016\/j.etap.2013.01.010","journal-title":"Environ Toxicol Pharmacol"},{"key":"11279_CR2","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1016\/j.biocel.2010.06.001","volume":"42","author":"KH Al-Gubory","year":"2010","unstructured":"Al-Gubory KH, Fowler PA, Garrel C (2010) The roles of cellular reactive oxygen species, oxidative stress, and antioxidants in pregnancy outcomes. Int J Biochem Cell Biol 42:1634\u20131650","journal-title":"Int J Biochem Cell Biol"},{"key":"11279_CR3","first-page":"55","volume":"8","author":"AE Al-Snafi","year":"2018","unstructured":"Al-Snafi AE (2018) Arabian medicinal plants with anti-inflammatory effects- plant-based review (part 1). IOSR J Pharmacy 8:55\u2013100","journal-title":"IOSR J Pharmacy"},{"key":"11279_CR4","unstructured":"Brain KR, Turner TD (1975) The practical evaluation of phytopharmaceuticals. Wright science technical, ISBN 0856080128:Dewey Number. 615\/.32\/028. Libraries Australia ID 754106, 1st edn, p 144"},{"key":"11279_CR5","first-page":"212","volume":"13","author":"A Buket","year":"2009","unstructured":"Buket A, Betul C, Sadik C (2009) Effects of benzimidazole fungicides, benomyl and carbendazim, on lipid peroxidation and antioxidant system in rat. Toxicol Lett 13:212","journal-title":"Toxicol Lett"},{"key":"11279_CR6","first-page":"46","volume":"7","author":"DM Cocchetto","year":"1983","unstructured":"Cocchetto DM, Bjornsson TD (1983) Methods for vascular access and collection of body fl. J Pharm Sci 7:46\u201392","journal-title":"J Pharm Sci"},{"key":"11279_CR7","doi-asserted-by":"crossref","unstructured":"De A, Bose R, Kumar A, Mozumdar S (2014) Worldwide pesticide use. In: targeted delivery of pesticides using biodegradable polymeric nanoparticles; springer: New Delhi, India 5\u20136","DOI":"10.1007\/978-81-322-1689-6_2"},{"key":"11279_CR8","first-page":"188","volume":"47","author":"S Dehdari","year":"2018","unstructured":"Dehdari S, Hajmehdipoor H (2018) Medicinal properties of Adiantum capillus-veneris Linn. in traditional medicine and modern phytotherapy. Iran J Public Health 47:188\u2013197","journal-title":"Iran J Public Health"},{"key":"11279_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10661-014-4142-6","volume":"187","author":"PA Devi","year":"2015","unstructured":"Devi PA, Paramasivam M, Prakasam V (2015) Degradation pattern and risk assessment of carbendazim and mancozeb in mango fruits. Environ Monit Assess 187:1\u20136. https:\/\/doi.org\/10.1007\/s10661-014-4142-6","journal-title":"Environ Monit Assess"},{"key":"11279_CR10","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.3109\/13880209.2014.957783","volume":"53","author":"A Eidi","year":"2015","unstructured":"Eidi A, Mortazavi P, Moghadam JZ, Mardani PM (2015) Hepatoprotective effects of Portulaca oleracea extract against CCl4-induced damage in rats. Pharm Biol 53:1042\u20131051","journal-title":"Pharm Biol"},{"key":"11279_CR11","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.fct.2011.03.018","volume":"49","author":"FM El-Demerdash","year":"2011","unstructured":"El-Demerdash FM (2011) Lipid peroxidation, oxidative stress, and acetylcholinesterase in rat brain exposed to organophosphate and pyrethroid insecticides. Food Chem Toxicol 49:1346\u20131352. https:\/\/doi.org\/10.1016\/j.fct.2011.03.018","journal-title":"Food Chem Toxicol"},{"key":"11279_CR12","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1007\/s10532-010-9353-0","volume":"21","author":"H Fang","year":"2012","unstructured":"Fang H, Wang Y, Gao C, Yan H, Dong B, Yu Y (2012) Isolation and characterization of Pseudomonas sp. CBW capable of degrading carbendazim. Biodegradation 21:939\u2013946. https:\/\/doi.org\/10.1007\/s10532-010-9353-0","journal-title":"Biodegradation"},{"key":"11279_CR13","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.aquatox.2008.05.012","volume":"89","author":"AL Ferreira","year":"2008","unstructured":"Ferreira AL, Loureiro S, Soares AM (2008) Toxicity prediction of binary combinations of cadmium, carbendazim, and low dissolved oxygen on Daphnia magna. Aquat Toxicol 89:28\u201339. https:\/\/doi.org\/10.1016\/j.aquatox.2008.05.012","journal-title":"Aquat Toxicol"},{"key":"11279_CR14","unstructured":"Finar IL (2003) Organic chemistry. Stereochemistry and the Chemistry of Natural Products 2:769\u2013771"},{"key":"11279_CR15","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1093\/carcin\/bgv039","volume":"36","author":"WH Goodson","year":"2015","unstructured":"Goodson WH, Lowe L, Carpenter DO, Gilbertson M, Manaf AA, Lopez de Cerain SA, Lasfar A (2015) Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis 36:254\u2013296. https:\/\/doi.org\/10.1093\/carcin\/bgv039","journal-title":"Carcinogenesis"},{"key":"11279_CR16","doi-asserted-by":"publisher","first-page":"38","DOI":"10.2174\/1871520616666161221113623","volume":"18","author":"K Goyal","year":"2018","unstructured":"Goyal K, Sharma A, Arya R, Sharma R, Gupta GK, Sharma AK (2018) Double edge sword behavior of carbendazim: a potent fungicide with anticancer therapeutic properties. Anti Cancer Agents Med Chem 18:38\u201345","journal-title":"Anti Cancer Agents Med Chem"},{"issue":"5","key":"11279_CR17","first-page":"295","volume":"32","author":"DM Haines","year":"1991","unstructured":"Haines DM, Clark EG (1991) Enzyme immunohistochemical staining of formalin-fixed tissues for diagnosis in veterinary pathology. Can Vet J 32(5):295\u2013302","journal-title":"Can Vet J"},{"key":"11279_CR18","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.cell.2008.01.020","volume":"132","author":"MS Hayden","year":"2008","unstructured":"Hayden MS, Ghosh S (2008) Shared principles in NF-kappa B signaling. Cell 132:344\u2013362","journal-title":"Cell"},{"key":"11279_CR19","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1007\/BF02535519","volume":"23","author":"DR Janero","year":"1988","unstructured":"Janero DR, Burghardt B (1988) Analysis of cardiac membrane phospholipids peroxidation kinetics as malondialdehyde: unspecificity of thiobarbituric acid-reactivity. Lipids 23:452\u2013458. https:\/\/doi.org\/10.1007\/BF02535519","journal-title":"Lipids"},{"key":"11279_CR20","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/S0076-6879(69)15041-7","volume":"15","author":"J Jarabak","year":"1969","unstructured":"Jarabak J (1969) Soluble 17b-hydroxysteroid dehydrogenase of human placenta. In: Raymond BC, ed. Methods Enzymol 15:746\u2013752","journal-title":"Methods Enzymol"},{"key":"11279_CR21","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.5897\/AJPP11.204","volume":"5","author":"Mz Jiang","year":"2011","unstructured":"Jiang Mz, Yan H, Wen Y, Li X-m (2011) In vitro and in vivo studies of antioxidant activities of flavonoids from Adiantum capillus-veneris L. Afr J Pharm Pharmacol 5:2079\u20132085","journal-title":"Afr J Pharm Pharmacol"},{"key":"11279_CR22","first-page":"3","volume":"10","author":"L Khodaie","year":"2015","unstructured":"Khodaie L, Esnaashari S, Bamdad-Moghaddam S (2015) Essential oil of arial parts of Adiantum capillus-veneris: chemical composition and antioxidant activity. J Nat Pharm Prod 10:3\u20137","journal-title":"J Nat Pharm Prod"},{"key":"11279_CR23","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s40557-017-0162-3","volume":"29","author":"KM Lee","year":"2017","unstructured":"Lee KM, Park SY, Lee K, Oh SS, Ko SB (2017) Pesticide metabolite and oxidative stress in male farmers exposed to pesticides. Ann Occup Environ Med 29:5","journal-title":"Ann Occup Environ Med"},{"key":"11279_CR24","doi-asserted-by":"publisher","first-page":"17023","DOI":"10.1038\/sigtrans.2017.23","volume":"2","author":"T Liu","year":"2017","unstructured":"Liu T, Zhang L, Joo D, Sun SC (2017) REVIEW NF-\u03baB signaling in inflammation. Signal Transduct Target Ther 2:17023. https:\/\/doi.org\/10.1038\/sigtrans.2017.23","journal-title":"Signal Transduct Target Ther"},{"key":"11279_CR25","doi-asserted-by":"publisher","first-page":"3903","DOI":"10.3892\/etm.2018.6715","volume":"16","author":"ZC Liu","year":"2018","unstructured":"Liu ZC, Meng LQ, Song JH, Gao J (2018) Dynamic protein expression of NF-\u03baB following rat intracerebral hemorrhage and its association with apoptosis. Exp Ther Med 16:3903\u20133908. https:\/\/doi.org\/10.3892\/etm.2018.6715","journal-title":"Exp Ther Med"},{"key":"11279_CR26","unstructured":"Lobin KK, Jaunky VC, Ramesh V (2017) A review of pesticide use in EU and African countries and associated policies in proceedings of 120th the IIER international conference (2017 Sep 15\u201316). Port Louis, Mauritius"},{"key":"11279_CR27","doi-asserted-by":"publisher","first-page":"3707","DOI":"10.7150\/jca.20239","volume":"8","author":"T Mehmood","year":"2017","unstructured":"Mehmood T, Maryam A, Tian X, Khan M, Ma T (2017) Santamarine inhibits NF-\u03baB and STAT3 activation and induces apoptosis in HepG2 liver cancer cells via oxidative stress. J Cancer 8:3707\u20133717","journal-title":"J Cancer"},{"key":"11279_CR28","first-page":"8440","volume":"5","author":"M Mehrdad","year":"2018","unstructured":"Mehrdad M, Masoomeh P, Habibolah N (2018) The effect of adiantum capilus veneris hydroalcoholic extract on plasma proteins and blood electrophoretic pattern in mice. IAJPS 5:8440\u20138445","journal-title":"IAJPS"},{"key":"11279_CR29","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1080\/01926230701481931","volume":"35","author":"JS Moffit","year":"2007","unstructured":"Moffit JS, Bryant BH, Hall SJ, Boekelheide K (2007) Dose-dependent effects of Sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis. Toxicol Pathol 35:719\u2013727","journal-title":"Toxicol Pathol"},{"key":"11279_CR30","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.fct.2011.03.018","volume":"49","author":"MS Moron","year":"2011","unstructured":"Moron MS, Depierre JW, Mannervik B (2011) Levels of glutathione, glutathione reductase and glutathione S organophosphate and pyrethroid insecticides. Food Chem Toxicol 49:1346\u20131352","journal-title":"Food Chem Toxicol"},{"key":"11279_CR31","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3389\/fimmu.2019.00085","volume":"10","author":"M Mussbacher","year":"2019","unstructured":"Mussbacher M, Salzmann M, Brostjan C, Hoesel B, Schoergenhofer C, Datler H, Hohensinner P, Bas\u00edlio J, Petzelbauer P, Assinger A, Schmid JA (2019) Cell type-specific roles of NF-\u03b2 linking inflammation and thrombosis. Front Immunol 10:85. https:\/\/doi.org\/10.3389\/fimmu.2019.00085","journal-title":"Front Immunol"},{"key":"11279_CR32","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/S0006-291X(72)80218-3","volume":"46","author":"M Nishikimi","year":"1972","unstructured":"Nishikimi M, Rao NA, Yagi K (1972) The occurrence of superoxide anion in the reaction of reduced phenazine methosulphate and molecular oxygen. Biochem Biophys Res Commun 46:849\u2013864","journal-title":"Biochem Biophys Res Commun"},{"key":"11279_CR33","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.fct.2017.02.010","volume":"102","author":"VU Nna","year":"2017","unstructured":"Nna VU, Usman UZ, Ofutet EO, Owu DU (2017) Quercetin exerts preventive ameliorative and prophylactic effects on cadmium chloride-induced oxidative stress in the uterus and ovaries of female Wistar rats. Food Chem Toxicol 102:143\u2013155","journal-title":"Food Chem Toxicol"},{"key":"11279_CR34","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1101\/cshperspect.a000034","volume":"1","author":"A Oeckinghaus","year":"2009","unstructured":"Oeckinghaus A, Ghosh S (2009) The NF-kappa B family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 1:34","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"11279_CR35","first-page":"351","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction, anal. Biochem 95:351\u2013358","journal-title":"Biochem"},{"key":"11279_CR36","first-page":"70","volume":"4","author":"SO Oyedemi","year":"2010","unstructured":"Oyedemi SO, Bradley G, Afolayan AJ (2010) In-vitro and -vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg. Afr J Pharm Pharmacol 4:70\u201378","journal-title":"Afr J Pharm Pharmacol"},{"key":"11279_CR37","first-page":"53","volume":"9","author":"J Parekh","year":"2006","unstructured":"Parekh J, Karathia N, Chanda S (2006) Antibacterial activity of Bauhinia variegata. J Biomed Res 9:53\u201356","journal-title":"J Biomed Res"},{"key":"11279_CR38","first-page":"411","volume":"7","author":"L Parker","year":"2016","unstructured":"Parker L, Stepto NK, Shaw CS, Serpiello FR, Anderson M, Hare DL, Levinger I (2016) Acute high-intensity interval exercise-induced redox signaling is associated with enhanced insulin sensitivity in obese middle-aged men. J Front Physiol 7:411\u2013422","journal-title":"J Front Physiol"},{"key":"11279_CR39","first-page":"1142","volume":"5","author":"F Pourmorad","year":"2009","unstructured":"Pourmorad F, Hosseinimehr SJ, Shahabima N (2009) Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr J Biotechnol 5:1142\u20131145","journal-title":"Afr J Biotechnol"},{"key":"11279_CR40","doi-asserted-by":"publisher","unstructured":"Rahman I, Aruna K, Biswas SK (2006) Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. 1:3159\u20133165. https:\/\/doi.org\/10.1038\/nprot.2006.378","DOI":"10.1038\/nprot.2006.378"},{"key":"11279_CR41","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.yrtph.2014.05.016","volume":"69","author":"EM Rama","year":"2014","unstructured":"Rama EM, Bortolan S, Vieira ML, Gerardin DC, Moreira EG (2014) Reproductive and possible hormonal effects of carbendazim. Regul Toxicol Pharmacol 69:476\u2013486. https:\/\/doi.org\/10.1016\/j.yrtph.2014.05.016","journal-title":"Regul Toxicol Pharmacol"},{"key":"11279_CR42","doi-asserted-by":"crossref","unstructured":"Ranjan B, Daundkar PS, Rampal S (2014) The ameliorative effect of selenium on carbendazim induced oral sub-chronic testicular toxicity in the bucks, small ruminant research 119107\u2013113","DOI":"10.1016\/j.smallrumres.2014.03.006"},{"key":"11279_CR43","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1530\/JOE-17-0023","volume":"233","author":"S Rattan","year":"2017","unstructured":"Rattan S, Zhou C, Chiang C, Mahalingam S, Brehm E, Flaws JA (2017) Exposure to endocrine disruptors during adulthood: consequences for female fertility. J Endocrinol 233:109\u2013129. https:\/\/doi.org\/10.1530\/JOE-17-0023","journal-title":"J Endocrinol"},{"key":"11279_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.13140\/RG.2.2.34232.03847","volume":"2","author":"SA Sakr","year":"2014","unstructured":"Sakr SA, Okdah YA, Ibrahim SA (2014) Effect of selenium on carbendazim - induced ovarian toxicity in albino rats: histomorphometric and histochemical study. Br Biomed Bull 2:1\u201315. https:\/\/doi.org\/10.13140\/RG.2.2.34232.03847","journal-title":"Br Biomed Bull"},{"key":"11279_CR45","first-page":"886","volume":"8","author":"MM Seif","year":"2014","unstructured":"Seif MM, Khalil FA, Abou-Arab AAK, Abdel-Aziz AS, Abou-Donia MA, Mohamed R (2014) Protective effect of Melissa officinalis L. against malathion toxicity and reproductive impairment in male rats. Int J Biol Biomol Agric Food Biotechnol Eng 8:886\u2013892","journal-title":"Int J Biol Biomol Agric Food Biotechnol Eng"},{"key":"11279_CR46","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1073\/pnas.1017213108","volume":"108","author":"K Shkolnik","year":"2011","unstructured":"Shkolnik K, Tadmor A, Ben-Dor S, Nevo N, Galiani D, Dekel N (2011) Reactive oxygen species are indispensable in ovulation. Proc Natl Acad Sci 108:1462\u20131467","journal-title":"Proc Natl Acad Sci"},{"key":"11279_CR47","first-page":"00013","volume":"1","author":"MM Sief","year":"2015","unstructured":"Sief MM, Khalil FA, Abou-Arab AAK, Abou Donia MA, El-Sherbiny AM, Mohamed SR (2015) Ameliorative role of Melissa Officinalis against hepatorenal toxicities of organophosphorus malathion in male rats. MOJ Toxicol 1:00013","journal-title":"MOJ Toxicol"},{"key":"11279_CR48","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/s10311-016-0566-572","volume":"14","author":"S Singh","year":"2016","unstructured":"Singh S, Singh N, Kumar V, Datta S, Wani AB, Singh D, Singh K, Singh J (2016) Toxicity, monitoring and biodegradation of the fungicide carbendazim. Environ Chem Lett 14:317\u2013329. https:\/\/doi.org\/10.1007\/s10311-016-0566-572","journal-title":"Environ Chem Lett"},{"key":"11279_CR49","doi-asserted-by":"publisher","first-page":"3985","DOI":"10.1007\/s11356-016-7901-9","volume":"25","author":"LF Spitta","year":"2018","unstructured":"Spitta LF, Diegeler S, Baumstark-Khan C, Hellweg CE (2018) An in-vitro approach for water quality determination: activation of NF-\u03baB as marker for cancer-related stress responses induced by anthropogenic pollutants of drinking water environ. Sci Pollut Res 25:3985\u20133995. https:\/\/doi.org\/10.1007\/s11356-016-7901-9","journal-title":"Sci Pollut Res"},{"key":"11279_CR50","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1038\/cr.2010.177","volume":"21","author":"SC Sun","year":"2011","unstructured":"Sun SC (2011) Non-canonical NF-kappa B signaling pathway. Cell Res 21:71\u201385","journal-title":"Cell Res"},{"key":"11279_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/cr.2011.1","volume":"21","author":"SC Sun","year":"2011","unstructured":"Sun SC, Liu ZG (2011) A special issue on NF-kappa B signaling and function. Cell Res 21:1\u20132","journal-title":"Cell Res"},{"key":"11279_CR52","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.it.2013.01.004","volume":"34","author":"SC Sun","year":"2013","unstructured":"Sun SC, Chang JH, Jin J (2013) Regulation of nuclear factor-kappa B in autoimmunity. Trends Immunol 34:282\u2013289","journal-title":"Trends Immunol"},{"key":"11279_CR53","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1111\/nyas.12458","volume":"1319","author":"FS Sutterwala","year":"2014","unstructured":"Sutterwala FS, Haasken S, Cassel SL (2014) Mechanism of NLRP3 inflammasome activation. Ann N Y Acad Sci 1319:82\u201395","journal-title":"Ann N Y Acad Sci"},{"key":"11279_CR54","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1377\/hlthaff.2010.1255","volume":"30","author":"P Sutton","year":"2011","unstructured":"Sutton P, Wallinga D, Perron J, Gottlieb M, Sayre L, Woodruff T (2011) Reproductive health and the industrialized food system: a point of intervention for health policy. Health Aff 30:888\u2013897","journal-title":"Health Aff"},{"key":"11279_CR55","first-page":"P1","volume-title":"Theory and practice of histological techniques","author":"K Suvarna","year":"2012","unstructured":"Suvarna K, Layton C, Bancroft J (2012) Theory and practice of histological techniques, 7th edn. Churchill Livingstone, New York, pp P1\u2013P645","edition":"7"},{"key":"11279_CR56","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1007\/s00204-003-0499-y","volume":"77","author":"KN Tzirogiannis","year":"2003","unstructured":"Tzirogiannis KN, Panoutsopoulos GI, Demonakou MD, Hereti RI, Alexandropoulou KN, Basayannis AC, Mykoniatis MG (2003) Time-course of cadmium-induced acute hepatotoxicity in the rat liver: the role of apoptosis. Arch Toxicol 77:694\u2013701","journal-title":"Arch Toxicol"},{"key":"11279_CR57","doi-asserted-by":"publisher","first-page":"18194","DOI":"10.1590\/s2175-97902019000118194","volume":"55","author":"J Upadhyay","year":"2019","unstructured":"Upadhyay J, Rana M, Bisht SS, Rana A, Durgapal S, Juyal V (2019) Biomarker responses (serum biochemistry) in pregnant female Wistar rats and histopathology of their neonates exposed prenatally to pesticides Braz. J Pharm Sci 55:18194. https:\/\/doi.org\/10.1590\/s2175-97902019000118194","journal-title":"J Pharm Sci"},{"key":"11279_CR58","first-page":"381","volume":"4","author":"M Veerappan","year":"2011","unstructured":"Veerappan M, Pandurangan M, Suriyamurthy M, Srikumar K (2011) Acute toxicological evaluation of low dose methyl 2-benzimidazole carbamate fungicide on male albino rats. Iran J Toxicol 4:381\u2013389","journal-title":"Iran J Toxicol"},{"key":"11279_CR59","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1016\/j.placenta.2008.09.003","volume":"29","author":"RP Webster","year":"2008","unstructured":"Webster RP, Roberts VH, Myatt L (2008) Protein nitration in placenta\u2013functional significance. Placenta 29:985\u2013994","journal-title":"Placenta"},{"key":"11279_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/786242","volume":"2012","author":"WC You","year":"2012","unstructured":"You WC, Li W, Zhuang Z, Tang Y, Lu HC, Ji XJ, Shen W, Shi JX, Zhou ML (2012) Biphasic activation of nuclear factor-kappa B in experimental models of subarachnoid hemorrhage in vivo and in vitro. Mediat Inflamm 2012:1\u201310. https:\/\/doi.org\/10.1155\/2012\/786242","journal-title":"Mediat Inflamm"},{"key":"11279_CR61","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/j.jep.2013.03.046","volume":"147","author":"Q Yuan","year":"2013","unstructured":"Yuan Q, Zhang X, Liu Z, Song S, Xue P, Wang J, Ruan J (2013) Ethanol extract of Adiantum capillus-veneris L. suppresses the production of inflammatory mediators by inhibiting NF-\u03baB activation. J Ethnopharmacol 147:603\u2013611","journal-title":"J Ethnopharmacol"},{"key":"11279_CR62","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s13578-015-0056-4","volume":"5","author":"H Zhang","year":"2015","unstructured":"Zhang H, Sun SC (2015) NF-kappa B in inflammation and renal diseases. Cell Biosci 5:63","journal-title":"Cell Biosci"},{"key":"11279_CR63","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s12868-017-0358-z","volume":"18","author":"M Zhang","year":"2017","unstructured":"Zhang M, Cui Z, Cui H, Wang Y, Zhong C (2017) Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-\u03baB signaling pathway. BMC Neurosci 18:42","journal-title":"BMC Neurosci"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-11279-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-020-11279-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-11279-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,8]],"date-time":"2021-05-08T17:38:28Z","timestamp":1620495508000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-020-11279-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,6]]},"references-count":63,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["11279"],"URL":"https:\/\/doi.org\/10.1007\/s11356-020-11279-w","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,6]]},"assertion":[{"value":"18 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The experimental approach and handling of animals are performed under the experiments managed approved by the Committee of Animal Ethics in the National Research Centre, Dokki, Cairo, Egypt (No: 19062). It was also performed after the guidelines as set out in the \u201cGuide for the Care and Use of Laboratory Animals\u201d and with the authorization of the committee for the Control and Supervision of Animal Experiments. All attempts had been taken to minimize the number and to reduce the animals\u2019 suffering.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}