{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T23:29:52Z","timestamp":1774999792600,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"23","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s11356-020-12057-4","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T02:17:08Z","timestamp":1612923428000},"page":"29455-29466","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Epidemiological assessment of antibiotic residues in dairy farm milk and farm waste and water in northern India"],"prefix":"10.1007","volume":"28","author":[{"given":"Prateek","family":"Jindal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasbir","family":"Bedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randhir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabinder","family":"Aulakh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jatinder Paul","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"key":"12057_CR1","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1016\/j.talanta.2006.07.003","volume":"70","author":"S Babic","year":"2006","unstructured":"Babic S, Asperger D, Mutavdzic D, Horvat AJM, Macan MK (2006) Solid phase extraction and HPLC determination of veterinary pharmaceuticals in wastewater. Talanta 70:732\u2013738","journal-title":"Talanta"},{"key":"12057_CR2","first-page":"260","volume":"61","author":"N Bilandzic","year":"2011","unstructured":"Bilandzic N, Kolanovic BS, Varenina I, Jurkovic Z (2011) Concentrations of veterinary drug residues in milk from individual farms in Croatia. Mljekarstvo 61:260\u2013267","journal-title":"Mljekarstvo"},{"issue":"18","key":"12057_CR3","doi-asserted-by":"publisher","first-page":"5649","DOI":"10.1073\/pnas.1503141112","volume":"112","author":"VTP Boeckel","year":"2015","unstructured":"Boeckel VTP, Brower C, Gilbert M, Grenfell B, Levin SA, Robinson TP, Laxminarayan R (2015) Global trends in antimicrobial use in food animals. Proc Natl Acad Sci 112(18):5649\u20135654","journal-title":"Proc Natl Acad Sci"},{"key":"12057_CR4","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0048-9697(02)00233-4","volume":"299","author":"ER Campagnolo","year":"2002","unstructured":"Campagnolo ER, Johnson KR, Karpati A, Rubin CS, Kolpin DW, Meyer MT, Esteban JE, Currier RW, Smith K, Thu KM, McGeehin M (2002) Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations. Sci Total Environ 299:89\u201395","journal-title":"Sci Total Environ"},{"key":"12057_CR5","unstructured":"Central pollution control board (CPCB). Annual report 2012-2013. Ministry of environment, forest and climate change, Government of India. Available at: https:\/\/cpcb.nic.in\/annual-report.php"},{"key":"12057_CR6","unstructured":"Centre for disease control and prevention (2013) Untreatable: Report by CDC details today\u2019s drug resistant health threats. Available at https:\/\/www.cdc.gov\/media\/releases\/2013\/p0916-untreatable.html"},{"key":"12057_CR7","first-page":"36","volume":"31","author":"T Christian","year":"2003","unstructured":"Christian T, Rudolf JS, Harald AF, Dirk S, Michael TM, Heiner EG (2003) Determination of antibiotic residues in manure, soil, and surface waters. Clean 31:36\u201344","journal-title":"Clean"},{"key":"12057_CR8","unstructured":"DADH & F (2012) Basic animal husbandry statistics. Department of Animal Husbandry, Dairying & Fisheries, Ministry of Agriculture, Government of India. Available at: https:\/\/dahd.gov.in\/"},{"key":"12057_CR9","unstructured":"DADH & F (2015) Basic Animal Husbandry Statistics. Department of Animal Husbandry, Dairying & Fisheries, Ministry of Agriculture, Government of India. Available at: https:\/\/dahd.nic.in\/sites\/default\/filess\/BAH_&_FS_Book.pdf"},{"key":"12057_CR10","unstructured":"EC (European Commission) (2002) Comission regulation of 2002\/657\/EC, 12 August. Implementing council directive 96\/23\/EC concerning the performance of analytical methods and the interpretation of results. Official Journal of European Communities, L 221\/8-L221\/36."},{"issue":"1","key":"12057_CR11","first-page":"5","volume":"34","author":"D Elizabeta","year":"2011","unstructured":"Elizabeta D, Zehra H, Biljana S, Pavle S, Risto U (2011) Screening of veterinary drug residues in milk from individual farms in Macedonia. Maced Vet Rev 34(1):5\u201313","journal-title":"Maced Vet Rev"},{"key":"12057_CR12","doi-asserted-by":"publisher","first-page":"26","DOI":"10.14202\/vetworld.2014.26-29","volume":"7","author":"A Gaurav","year":"2014","unstructured":"Gaurav A, Gill JPS, Aulakh RS, Bedi JS (2014) ELISA based monitoring and analysis of tetracycline residues in cattle milk in Punjab. Vet World 7:26\u201329","journal-title":"Vet World"},{"key":"12057_CR13","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0038-0717(98)00117-5","volume":"31","author":"BS Griffiths","year":"1999","unstructured":"Griffiths BS, Ritz K, Ebblewhite N, Dobson G (1999) Soil microbial community structure: effects of substrate loading rates. Soil Biol Biochem 31:145\u2013153","journal-title":"Soil Biol Biochem"},{"key":"12057_CR14","unstructured":"Grover CR, Bhavadesan M (2016) Antibiotic residues in milk: a public health concern. In: National Conference on Food Safety and Environmental Toxins. New Delhi: Centre for Science and Environment. p.47. (http:\/\/www.cseindia.org\/userfiles\/antibiotic_milk_chandram.pdf)"},{"issue":"15","key":"12057_CR15","first-page":"51","volume":"31","author":"YY He","year":"2010","unstructured":"He YY, Luo JL, Wu ZY, Lu W, Xie GQ (2010) The influence of feedstuffs on fecal production and fecal pollutants. J Feed Sci 31(15):51\u201354","journal-title":"J Feed Sci"},{"key":"12057_CR16","unstructured":"ICAR (Indian Council of Agricultural Research) (2013) Handbook of Animal Husbandary, 10th Edn"},{"issue":"3","key":"12057_CR17","first-page":"956","volume":"5","author":"MM Islam","year":"2016","unstructured":"Islam MM, Anjum S, Modi RJ, Wadhwani KN (2016) Scenario of livestock and poultry in India and their contribution to national economy. Int J Environ Sci Technol 5(3):956\u2013965","journal-title":"Int J Environ Sci Technol"},{"key":"12057_CR18","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on food additives) (2004) WHO technical report series no. 925 sixty two meeting of JECFA. ftp:\/\/ftp. fao.org\/es\/esn\/jecfa\/call_63.pdf"},{"key":"12057_CR19","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1016\/j.foodcont.2010.05.004","volume":"21","author":"C Juan","year":"2010","unstructured":"Juan C, Molto JC, Manes J, Font G (2010) Determination of macrolide and lincosamide antibiotics by pressurized liquid extraction and liquid chromatography tandem mass spectrometry in meat and milk. Food Control 21:1703\u20131709","journal-title":"Food Control"},{"key":"12057_CR20","doi-asserted-by":"publisher","first-page":"4652","DOI":"10.1016\/j.scitotenv.2009.04.047","volume":"407","author":"A Karci","year":"2009","unstructured":"Karci A, Balcioglu IA (2009) Investigation of the tetracycline, sulfonamide, and fluoroquinolone antimicrobial compounds in animal manure and agricultural soils in Turkey. Sci Total Environ 407:4652\u20134664","journal-title":"Sci Total Environ"},{"issue":"3","key":"12057_CR21","doi-asserted-by":"publisher","first-page":"e1001974","DOI":"10.1371\/journal.pmed.1001974","volume":"13","author":"R Laxminarayan","year":"2013","unstructured":"Laxminarayan R, Chaudhury RR (2013) Antibiotic resistance in India: drivers and opportunities for action. PLoS Med 13(3):e1001974","journal-title":"PLoS Med"},{"key":"12057_CR22","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3390\/ani4020146","volume":"4","author":"DI Masse","year":"2014","unstructured":"Masse DI, CataSaady NM, Gilbert Y (2014) Potential of biological processes to eliminate antibiotics in livestock manure: an overview. Animals 4:146\u2013163","journal-title":"Animals"},{"key":"12057_CR23","unstructured":"Moudgil P (2017) \u2018Multi-residue detection of antibiotics in milk and role of dairy farm managerial practices in occurrence of residues.\u2019Ph.D. Dissertation.Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India"},{"issue":"6","key":"12057_CR24","doi-asserted-by":"publisher","first-page":"641","DOI":"10.17221\/22\/2011-CJFS","volume":"29","author":"P Navratilova","year":"2011","unstructured":"Navratilova P, Ivana B, Vyhnalkova J, Vorlova L (2011) Fluoroquinolone residues in raw cow\u2019s milk. Czech J Food Sci 29(6):641\u2013646","journal-title":"Czech J Food Sci"},{"key":"12057_CR25","doi-asserted-by":"crossref","unstructured":"Pinheiro A, Albano R M R, Alves T C, Kaufmann V and D Silva M R (2013) Veterinary antibiotics and hormones in water from application of pig slurry to soil. Agricultural Water Management 129:1\u20138","DOI":"10.1016\/j.agwat.2013.06.019"},{"key":"12057_CR26","unstructured":"Sergeant, ESG (2019) Epitools epidemiological calculators. Ausvet Pty Ltd. Available at: http:\/\/epitools.ausvet.com.au"},{"key":"12057_CR27","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.scitotenv.2016.04.140","volume":"563\u2013564","author":"RP Tasho","year":"2016","unstructured":"Tasho RP, Cho JY (2016) Veterinary antibiotics in animal waste, its distribution in soil and uptake by plants: a review. Sci Total Environ 563\u2013564:366\u2013376","journal-title":"Sci Total Environ"},{"issue":"1","key":"12057_CR28","first-page":"81","volume":"4","author":"N Vragovic","year":"2012","unstructured":"Vragovic N, Bazulic D, Zdolec N (2012) Dietary exposure assessment of \u00df-lactam antibiotic residues in milk on Croatian market. Croat J Food Sci Technol 4(1):81\u201384","journal-title":"Croat J Food Sci Technol"},{"key":"12057_CR29","doi-asserted-by":"crossref","unstructured":"Wang H, Wang N, Wang B, Zhao Q, Fang H, Fu C, Tang C, Jiang F, Zhou Y, Chen Y, Jiang Q (2016) Antibiotics in drinking water in Shanghai and its contribution to antibiotic exposure of school children. Environ Sci Technol:1\u201334","DOI":"10.1021\/acs.est.5b05749"},{"issue":"10","key":"12057_CR30","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1016\/j.chemosphere.2010.11.067","volume":"82","author":"R Wei","year":"2011","unstructured":"Wei R, Ge F, Huang S, Chen M, Wang R (2011) Occurrence of veterinary antibiotics in animal wastewater and surface water around farms in Jiangsu Province, China. Chemosphere 82(10):1408\u20131414","journal-title":"Chemosphere"},{"key":"12057_CR31","unstructured":"WHO (World Health Organization) (2016) WHO global stratergy for containment of Antimicrobial resistance. Available at: https:\/\/www.who.int\/drugresistance\/WHO_Global_Strategy_English.pdf"},{"issue":"9","key":"12057_CR32","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1016\/S1872-2040(08)60063-8","volume":"36","author":"H Xian-Gang","year":"2008","unstructured":"Xian-Gang H, Yi L, Qi-Xing Z, Lin X (2008) Determination of thirteen antibiotics residues in manure by solid phase extraction and high performance liquid chromatography. Chin J Anal Chem 36(9):1162\u20131166","journal-title":"Chin J Anal Chem"},{"key":"12057_CR33","unstructured":"Ye Z, Weinberg HS (2004) Occurrence of Antibiotics in Drinking Water. U. S. Geological Survey, Kansas. Available at: file:\/\/\/C:\/Users\/HP%20PC\/Downloads\/Occurrence_of_Antibiotics_in_Drinking_Water.pdf"},{"key":"12057_CR34","doi-asserted-by":"crossref","unstructured":"Zhang X, Li Y, Liu B, Wang J, Feng C, Gao M and Wang L (2014) Prevalence of veterinary antibiotics and antibiotic-resistant Escherichia coli in the surface water of a livestock production region in Northern China. PLoS ONE 9(11):1\u201311","DOI":"10.1371\/journal.pone.0111026"},{"key":"12057_CR35","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.foodchem.2016.02.142","volume":"204","author":"Z Zhang","year":"2016","unstructured":"Zhang Z, Xiaowei L, Shuangyang D, Haiyang J, Jianzhong S, Xi X (2016) Multi residue analysis of sulfonamides, quinolones, and tetracyclines in animal tissues by ultra-high performance liquid chromatography-tandem mass spectrometry. Food Chem 204:252\u2013262","journal-title":"Food Chem"},{"key":"12057_CR36","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.scitotenv.2012.11.087","volume":"444","author":"LJ Zhou","year":"2013","unstructured":"Zhou LJ, Ying GG, Liu S, Zhang RQ, Lai HJ, Chen ZF, Pan CG (2013) Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China. Sci Total Environ 444:183\u2013195","journal-title":"Sci Total Environ"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-12057-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-020-12057-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-12057-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T13:37:11Z","timestamp":1624455431000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-020-12057-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,9]]},"references-count":36,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["12057"],"URL":"https:\/\/doi.org\/10.1007\/s11356-020-12057-4","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,9]]},"assertion":[{"value":"8 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Ethical approval was obtained by the institutional animal ethics committee (IAEC), Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana (Registration no. 497\/GO\/Re\/SL\/01\/CPCSEA). The ethical approval number allotted to the current study on consent was GADVASU\/2017\/IAEC\/41\/13.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"As part of the informed consent process, the consent document was designed to provide information to potential subjects about a research study so they can make an informed decision about their participation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}