{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:07:18Z","timestamp":1792807638193,"version":"4.5.0"},"reference-count":76,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s11356-020-12171-3","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T10:03:53Z","timestamp":1609754633000},"page":"12178-12189","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Enrichment of antibiotic resistance genes (ARGs) in polyaromatic hydrocarbon\u2013contaminated soils: a major challenge for environmental health"],"prefix":"10.1007","volume":"28","author":[{"given":"Anand Prakash","family":"Maurya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jina","family":"Rajkumari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piyush","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,4]]},"reference":[{"key":"12171_CR1","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1186\/1471-2180-11-252","volume":"11","author":"AA Adebusuyi","year":"2011","unstructured":"Adebusuyi AA, Foght JM (2011) An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a. BMC Microbiol 11:252. https:\/\/doi.org\/10.1186\/1471-2180-11-252","journal-title":"BMC Microbiol"},{"key":"12171_CR2","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1007\/s00267-017-0896-2","volume":"60","author":"OO Alegbeleye","year":"2017","unstructured":"Alegbeleye OO, Opeolu BO, Jackson VA (2017) Polycyclic aromatic hydrocarbons: a critical review of environmental occurrence and bioremediation. Environ Manag 60:758\u2013783. https:\/\/doi.org\/10.1007\/s00267-017-0896-2","journal-title":"Environ Manag"},{"key":"12171_CR3","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.tim.2006.02.006","volume":"14","author":"C Baker-austin","year":"2006","unstructured":"Baker-austin C, Wright MS, Stepanauskas R, Mcarthur JV (2006) Co-selection of antibiotic and metal resistance. Trends Microbiol 14:176\u2013182. https:\/\/doi.org\/10.1016\/j.tim.2006.02.006","journal-title":"Trends Microbiol"},{"key":"12171_CR4","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1111\/j.1365-2672.2007.03621.x","volume":"104","author":"O Ben Said","year":"2008","unstructured":"Ben Said O, Go\u00f1i-Urriza MS, El Bour M et al (2008) Characterization of aerobic polycyclic aromatic hydrocarbon-degrading bacteria from Bizerte lagoon sediments, Tunisia. J Appl Microbiol 104:987\u2013997. https:\/\/doi.org\/10.1111\/j.1365-2672.2007.03621.x","journal-title":"J Appl Microbiol"},{"key":"12171_CR5","doi-asserted-by":"publisher","unstructured":"Bengtsson-palme J, Kristiansson E, Larsson DGJ (2018) Environmental factors influencing the development and spread of antibiotic resistance. 68\u201380. https:\/\/doi.org\/10.1093\/femsre\/fux053","DOI":"10.1093\/femsre\/fux053"},{"key":"12171_CR6","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1038\/nrmicro3439","volume":"13","author":"TU Berendonk","year":"2015","unstructured":"Berendonk TU, Manaia CM, Merlin C, Fatta-Kassinos D, Cytryn E, Walsh F, B\u00fcrgmann H, S\u00f8rum H, Norstr\u00f6m M, Pons MN, Kreuzinger N, Huovinen P, Stefani S, Schwartz T, Kisand V, Baquero F, Martinez JL (2015) Tackling antibiotic resistance: the environmental framework. Nat Rev Microbiol 13:310\u2013317","journal-title":"Nat Rev Microbiol"},{"key":"12171_CR7","doi-asserted-by":"publisher","first-page":"3789","DOI":"10.26452\/ijrps.v10i4.1770","volume":"10","author":"N Bhagat","year":"2019","unstructured":"Bhagat N, Roy P, Singh S, Allen T (2019) Isolation and characterization of bacteria with multiple traits: hydrocarbon degradation, antibiotic-resistant and metal tolerant. Int J Res Pharm Sci 10:3789\u20133795","journal-title":"Int J Res Pharm Sci"},{"key":"12171_CR8","doi-asserted-by":"publisher","first-page":"5620","DOI":"10.1021\/es501098g","volume":"48","author":"TR Burch","year":"2014","unstructured":"Burch TR, Sadowsky MJ, LaPara TM (2014) Fate of antibiotic resistance genes and class 1 integrons in soil microcosms following the application of treated residual municipal wastewater solids. Environ Sci Technol 48:5620\u20135627. https:\/\/doi.org\/10.1021\/es501098g","journal-title":"Environ Sci Technol"},{"key":"12171_CR9","doi-asserted-by":"publisher","unstructured":"Busch A, Mesa-Torres N, Krell T (2018) The family of two-component systems that regulate hydrocarbon degradation pathways. In: Krell T. (eds) Cellular ecophysiology of microbe. handbook of hydrocarbon and lipid microbiology. Springer, Cham. https:\/\/doi.org\/10.1007\/978-3-319-20796-4_6-1","DOI":"10.1007\/978-3-319-20796-4_6-1"},{"key":"12171_CR10","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0168-6496(95)00040-H","volume":"18","author":"JIA Campbell","year":"1995","unstructured":"Campbell JIA, Jacobsen CS, S\u00f8rensen J (1995) Species variation and plasmid incidence among fluorescent Pseudomonas strains isolated from agricultural and industrial soils. FEMS Microbiol Ecol 18:51\u201362. https:\/\/doi.org\/10.1016\/0168-6496(95)00040-H","journal-title":"FEMS Microbiol Ecol"},{"key":"12171_CR11","doi-asserted-by":"publisher","first-page":"15280","DOI":"10.1073\/pnas.0606924103","volume":"103","author":"PSG Chain","year":"2006","unstructured":"Chain PSG, Denef VJ, Konstantinidis KT, Vergez LM, Agullo L, Reyes VL, Hauser L, Cordova M, Gomez L, Gonzalez M, Land M, Lao V, Larimer F, LiPuma JJ, Mahenthiralingam E, Malfatti SA, Marx CJ, Parnell JJ, Ramette A, Richardson P, Seeger M, Smith D, Spilker T, Sul WJ, Tsoi TV, Ulrich LE, Zhulin IB, Tiedje JM (2006) Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility. Proc Natl Acad Sci U S A 103:15280\u201315287. https:\/\/doi.org\/10.1073\/pnas.0606924103","journal-title":"Proc Natl Acad Sci U S A"},{"key":"12171_CR12","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.envpol.2016.11.047","volume":"220","author":"B Chen","year":"2017","unstructured":"Chen B, He R, Yuan K, Chen E, Lin L, Chen X, Sha S, Zhong J, Lin L, Yang L, Yang Y, Wang X, Zou S, Luan T (2017) Polycyclic aromatic hydrocarbons (PAHs) enriching antibiotic resistance genes (ARGs) in the soils. Environ Pollut 220:1005\u20131013. https:\/\/doi.org\/10.1016\/j.envpol.2016.11.047","journal-title":"Environ Pollut"},{"key":"12171_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmicb.2019.01916","volume":"10","author":"J Chen","year":"2019","unstructured":"Chen J, Li J, Zhang H et al (2019) Bacterial heavy-metal and antibiotic resistance genes in a copper Tailing Dam Area in Northern China. Front Microbiol 10:1\u201312. https:\/\/doi.org\/10.3389\/fmicb.2019.01916","journal-title":"Front Microbiol"},{"key":"12171_CR14","doi-asserted-by":"publisher","first-page":"29191","DOI":"10.1007\/s11356-020-09287-x","volume":"27","author":"J Cheng","year":"2020","unstructured":"Cheng J, Tang X, Liu C (2020) Occurrence and distribution of antibiotic resistance genes in various rural environmental media. Environ Sci Pollut Res 27:29191\u201329203. https:\/\/doi.org\/10.1007\/s11356-020-09287-x","journal-title":"Environ Sci Pollut Res"},{"key":"12171_CR15","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1039\/c9em00606k","volume":"22","author":"CJ Cunningham","year":"2020","unstructured":"Cunningham CJ, Kuyukina MS, Ivshina IB, Konev AI, Peshkur TA, Knapp CW (2020a) Potential risks of antibiotic resistant bacteria and genes in bioremediation of petroleum hydrocarbon contaminated soils. Environ Sci Process Impacts 22:1110\u20131124. https:\/\/doi.org\/10.1039\/c9em00606k","journal-title":"Environ Sci Process Impacts"},{"key":"12171_CR16","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1039\/c9em00606k","volume":"22","author":"CJ Cunningham","year":"2020","unstructured":"Cunningham CJ, Kuyukina MS, Ivshina IB, Konev AI, Peshkur TA, Knapp CW (2020b) Potential risks of antibiotic resistant bacteria and genes in bioremediation of petroleum hydrocarbon contaminated soils. Environ Sci Process Impacts 22:1110\u20131124. https:\/\/doi.org\/10.1039\/c9em00606k","journal-title":"Environ Sci Process Impacts"},{"key":"12171_CR17","doi-asserted-by":"publisher","unstructured":"Das N, Kotoky R, Maurya AP, Bhuyan B, Pandey P (2020) Paradigm shift in antibiotic-resistome of petroleum hydrocarbon contaminated soil. Sci Total Environ 143777. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.143777","DOI":"10.1016\/j.scitotenv.2020.143777"},{"key":"12171_CR18","doi-asserted-by":"publisher","first-page":"e1002184","DOI":"10.1371\/journal.pmed.1002184","volume":"13","author":"MEA de Kraker","year":"2016","unstructured":"de Kraker MEA, Stewardson AJ, Harbarth S (2016) Will 10 million people die a year due to antimicrobial resistance by 2050? PLoS Med 13:e1002184. https:\/\/doi.org\/10.1371\/journal.pmed.1002184","journal-title":"PLoS Med"},{"key":"12171_CR19","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1038\/ismej.2010.208","volume":"5","author":"H Elsaied","year":"2011","unstructured":"Elsaied H, Stokes HW, Kitamura K, Kurusu Y, Kamagata Y, Maruyama A (2011) Marine integrons containing novel integrase genes, attachment sites, attI, and associated gene cassettes in polluted sediments from Suez and Tokyo Bays. ISME J 5:1162\u20131177. https:\/\/doi.org\/10.1038\/ismej.2010.208","journal-title":"ISME J"},{"key":"12171_CR20","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fmicb.2019.01448","volume":"10","author":"P Fang","year":"2019","unstructured":"Fang P, Peng F, Gao X, Xiao P, Yang J (2019) Decoupling the dynamics of bacterial taxonomy and antibiotic resistance function in a subtropical urban reservoir as revealed by high-frequency sampling. Front Microbiol 10:10. https:\/\/doi.org\/10.3389\/fmicb.2019.01448","journal-title":"Front Microbiol"},{"key":"12171_CR21","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/j.1574-6968.2009.01646.x","volume":"296","author":"MR Gillings","year":"2009","unstructured":"Gillings MR, Holley MP, Stokes HW (2009) Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilms. FEMS Microbiol Lett 296:282\u2013288. https:\/\/doi.org\/10.1111\/j.1574-6968.2009.01646.x","journal-title":"FEMS Microbiol Lett"},{"key":"12171_CR22","doi-asserted-by":"publisher","first-page":"3243","DOI":"10.1021\/es0264448","volume":"37","author":"EM Golet","year":"2003","unstructured":"Golet EM, Xifra I, Siegrist H, Alder AC, Giger W (2003) Environmental exposure assessment of fluoroquinolone antibacterial agents from sewage to soil. Environ Sci Technol 37:3243\u20133249. https:\/\/doi.org\/10.1021\/es0264448","journal-title":"Environ Sci Technol"},{"key":"12171_CR23","doi-asserted-by":"publisher","first-page":"9283","DOI":"10.1007\/s11356-018-1465-9","volume":"25","author":"AV Gorovtsov","year":"2018","unstructured":"Gorovtsov AV, Sazykin IS, Sazykina MA (2018) The influence of heavy metals, polyaromatic hydrocarbons, and polychlorinated biphenyls pollution on the development of antibiotic resistance in soils. Environ Sci Pollut Res 25:9283\u20139292. https:\/\/doi.org\/10.1007\/s11356-018-1465-9","journal-title":"Environ Sci Pollut Res"},{"key":"12171_CR24","doi-asserted-by":"publisher","first-page":"2164","DOI":"10.1016\/S0140-6736(16)31533-1","volume":"388","author":"W Graham","year":"2016","unstructured":"Graham W, Woodd S, Byass P, Filippi V, Gon G, Virgo S, Chou D, Hounton S, Lozano R, Pattinson R, Singh S (2016) Diversity and divergence: the dynamic burden of poor maternal health. Lancet 388:2164\u20132175","journal-title":"Lancet"},{"key":"12171_CR25","doi-asserted-by":"publisher","first-page":"6233","DOI":"10.1128\/JB.185.21.6233-6240.2003","volume":"185","author":"EM Hearn","year":"2003","unstructured":"Hearn EM, Dennis JJ, Gray MR, Foght JM (2003) Identification and characterization of the emhABC efflux system for polycyclic aromatic hydrocarbons in Pseudomonas fluorescens cLP6a. J Bacteriol 185:6233\u20136240. https:\/\/doi.org\/10.1128\/JB.185.21.6233-6240.2003","journal-title":"J Bacteriol"},{"key":"12171_CR26","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.resmic.2014.05.035","volume":"165","author":"L Hemala","year":"2014","unstructured":"Hemala L, Zhang D, Margesin R (2014) Cold-active antibacterial and antifungal activities and antibiotic resistance of bacteria isolated from an alpine hydrocarbon-contaminated industrial site. Res Microbiol 165:447\u2013456. https:\/\/doi.org\/10.1016\/j.resmic.2014.05.035","journal-title":"Res Microbiol"},{"key":"12171_CR27","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.ecoleng.2017.02.051","volume":"108","author":"TTD Hsu","year":"2017","unstructured":"Hsu TTD, Mitsch WJ, Martin JF, Lee J (2017) Towards sustainable protection of public health: the role of an urban wetland as a frontline safeguard of pathogen and antibiotic resistance spread. Ecol Eng 108:547\u2013555. https:\/\/doi.org\/10.1016\/j.ecoleng.2017.02.051","journal-title":"Ecol Eng"},{"key":"12171_CR28","doi-asserted-by":"publisher","first-page":"104880","DOI":"10.1016\/j.envint.2019.05.074","volume":"130","author":"PMC Huijbers","year":"2019","unstructured":"Huijbers PMC, Flach CF, Larsson DGJ (2019) A conceptual framework for the environmental surveillance of antibiotics and antibiotic resistance. Environ Int 130:104880. https:\/\/doi.org\/10.1016\/j.envint.2019.05.074","journal-title":"Environ Int"},{"key":"12171_CR29","doi-asserted-by":"publisher","first-page":"5111","DOI":"10.1128\/AEM.70.9.5111-5118.2004","volume":"70","author":"ML Hutchison","year":"2004","unstructured":"Hutchison ML, Walters LD, Moore A, Crookes KM, Avery SM (2004) Effect of length of time before incorporation on survival of pathogenic bacteria present in livestock wastes applied to agricultural soil. Appl Environ Microbiol 70:5111\u20135118. https:\/\/doi.org\/10.1128\/AEM.70.9.5111-5118.2004","journal-title":"Appl Environ Microbiol"},{"key":"12171_CR30","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1016\/j.envpol.2017.10.006","volume":"233","author":"HM Jang","year":"2018","unstructured":"Jang HM, Kim YB, Choi S, Lee Y, Shin SG, Unno T, Kim YM (2018) Prevalence of antibiotic resistance genes from effluent of coastal aquaculture, South Korea. Environ Pollut 233:1049\u20131057. https:\/\/doi.org\/10.1016\/j.envpol.2017.10.006","journal-title":"Environ Pollut"},{"key":"12171_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10934529.2020.1744998","volume":"55","author":"S Jiang","year":"2020","unstructured":"Jiang S, Yang J, Fang D (2020) Histological, oxidative and immune changes in response to 9,10-phenanthrenequione, retene and phenanthrene in Takifugu obscurus liver. J Environ Sci Heal Part A 55:1\u201310. https:\/\/doi.org\/10.1080\/10934529.2020.1744998","journal-title":"J Environ Sci Heal Part A"},{"key":"12171_CR32","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.envpol.2006.07.012","volume":"146","author":"MM Jussila","year":"2007","unstructured":"Jussila MM, Zhao J, Suominen L, Lindstr\u00f6m K (2007) TOL plasmid transfer during bacterial conjugation in vitro and rhizoremediation of oil compounds in vivo. Environ Pollut 146:510\u2013524. https:\/\/doi.org\/10.1016\/j.envpol.2006.07.012","journal-title":"Environ Pollut"},{"key":"12171_CR33","doi-asserted-by":"publisher","first-page":"8891","DOI":"10.1021\/es103215b","volume":"44","author":"F Kang","year":"2010","unstructured":"Kang F, Gao Y, Wang Q (2010) Inhibition of free DNA degradation by the deformation of DNA exposed to trace polycyclic aromatic hydrocarbon contaminants. Environ Sci Technol 44:8891\u20138896. https:\/\/doi.org\/10.1021\/es103215b","journal-title":"Environ Sci Technol"},{"key":"12171_CR34","doi-asserted-by":"publisher","first-page":"10340","DOI":"10.1021\/acs.est.5b02293","volume":"49","author":"F Kang","year":"2015","unstructured":"Kang F, Hu X, Liu J, Gao Y (2015) Noncovalent binding of polycyclic aromatic hydrocarbons with genetic bases reducing the in vitro lateral transfer of antibiotic resistant genes. Environ Sci Technol 49:10340\u201310348. https:\/\/doi.org\/10.1021\/acs.est.5b02293","journal-title":"Environ Sci Technol"},{"key":"12171_CR35","first-page":"576","volume":"67","author":"Y Kang","year":"2017","unstructured":"Kang Y, Shen M, Xia D et al (2017) Caution of intensified spread of antibiotic resistance genes by inadvertent introduction of beneficial bacteria into soil. Acta Agric Scand Sect B 67:576\u2013582","journal-title":"Acta Agric Scand Sect B"},{"key":"12171_CR36","doi-asserted-by":"publisher","first-page":"e27300","DOI":"10.1371\/journal.pone.0027300","volume":"6","author":"CW Knapp","year":"2011","unstructured":"Knapp CW, McCluskey SM, Singh BK et al (2011) Antibiotic resistance gene abundances correlate with metal and geochemical conditions in archived Scottish soils. PLoS One 6:e27300. https:\/\/doi.org\/10.1371\/journal.pone.0027300","journal-title":"PLoS One"},{"key":"12171_CR37","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1371\/journal.pone.0231128","volume":"15","author":"Q Li","year":"2020","unstructured":"Li Q, Zhang Q (2020) Prevalence and pollution characteristics of antibiotic resistant genes in one high anthropogenically-impacted river. PLoS One 15:15. https:\/\/doi.org\/10.1371\/journal.pone.0231128","journal-title":"PLoS One"},{"key":"12171_CR38","doi-asserted-by":"publisher","first-page":"4587","DOI":"10.1007\/s11356-014-3665-2","volume":"22","author":"J Li","year":"2015","unstructured":"Li J, Cheng W, Xu L, Strong PJ, Chen H (2015) Antibiotic-resistant genes and antibiotic-resistant bacteria in the effluent of urban residential areas, hospitals, and a municipal wastewater treatment plant system. Environ Sci Pollut Res 22:4587\u20134596. https:\/\/doi.org\/10.1007\/s11356-014-3665-2","journal-title":"Environ Sci Pollut Res"},{"key":"12171_CR39","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1038\/ismej.2016.155","volume":"11","author":"L-G Li","year":"2017","unstructured":"Li L-G, Xia Y, Zhang T (2017) Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection. ISME J 11:651\u2013662. https:\/\/doi.org\/10.1038\/ismej.2016.155","journal-title":"ISME J"},{"key":"12171_CR40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108249","volume":"9","author":"J Liu","year":"2014","unstructured":"Liu J, Liu S, Sun K, Sheng Y, Gu Y, Gao Y (2014) Colonization on root surface by a phenanthrene-degrading endophytic bacterium and its application for reducing plant phenanthrene contamination. PLoS One 9:e108249","journal-title":"PLoS One"},{"key":"12171_CR41","doi-asserted-by":"publisher","first-page":"17005","DOI":"10.3390\/ijms160817005","volume":"16","author":"P Liu","year":"2015","unstructured":"Liu P, Chen X, Huang Q, Chen W (2015) The role of CzcRS two-component systems in the heavy metal resistance of Pseudomonas putida X4. Int J Mol Sci 16:17005\u201317017. https:\/\/doi.org\/10.3390\/ijms160817005","journal-title":"Int J Mol Sci"},{"key":"12171_CR42","doi-asserted-by":"publisher","first-page":"e02296","DOI":"10.1128\/mBio.02296-16","volume":"8","author":"C Loot","year":"2017","unstructured":"Loot C, Nivina A, Cury J, Escudero JA, Ducos-Galand M, Bikard D, Rocha EPC, Mazel D (2017) Differences in integron cassette excision dynamics shape a trade-off between evolvability and genetic capacitance. MBio 8:e02296\u2013e02216. https:\/\/doi.org\/10.1128\/mBio.02296-16","journal-title":"MBio"},{"key":"12171_CR43","doi-asserted-by":"publisher","first-page":"246","DOI":"10.3390\/w10030246","volume":"10","author":"J Lu","year":"2018","unstructured":"Lu J, Tian Z, Yu J, Yang M, Zhang Y (2018) Distribution and abundance of antibiotic resistance genes in sand settling reservoirs and drinking water treatment plants across the Yellow River, China. Water 10:246. https:\/\/doi.org\/10.3390\/w10030246","journal-title":"Water"},{"key":"12171_CR44","doi-asserted-by":"publisher","unstructured":"Ma L, Li B, Jiang XT et al (2017) Catalogue of antibiotic resistome and host-tracking in drinking water deciphered by a large scale survey.\u00a0Microbiome 5:154. https:\/\/doi.org\/10.1186\/s40168-017-0369-0","DOI":"10.1186\/s40168-017-0369-0"},{"key":"12171_CR45","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1126\/science.1159483","volume":"321","author":"JL Mart\u00ednez","year":"2008","unstructured":"Mart\u00ednez JL (2008) Antibiotics and antibiotic resistance genes in natural environments. Science (80- ) 321:365\u2013367","journal-title":"Science (80- )"},{"key":"12171_CR46","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1111\/j.1574-6976.2008.00157.x","volume":"33","author":"JL Martinez","year":"2009","unstructured":"Martinez JL, S\u00e1nchez MB, Mart\u00ednez-Solano L, Hernandez A, Garmendia L, Fajardo A, Alvarez-Ortega C (2009) Functional role of bacterial multidrug efflux pumps in microbial natural ecosystems. FEMS Microbiol Rev 33:430\u2013449","journal-title":"FEMS Microbiol Rev"},{"key":"12171_CR47","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jece.2017.11.069","volume":"6","author":"R Maruzani","year":"2018","unstructured":"Maruzani R, Canali A, Serafim V, Munoz LP, Shah AJ, Perito B, Marvasi M (2018a) Effect of anthropogenic pollution on the fitness of tetracycline sensitive Shigella flexneri in Thames river water. J Environ Chem Eng 6:19\u201327. https:\/\/doi.org\/10.1016\/j.jece.2017.11.069","journal-title":"J Environ Chem Eng"},{"key":"12171_CR48","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jece.2017.11.069","volume":"6","author":"R Maruzani","year":"2018","unstructured":"Maruzani R, Canali A, Serafim V, Munoz LP, Shah AJ, Perito B, Marvasi M (2018b) Effect of anthropogenic pollution on the fitness of tetracycline sensitive Shigella flexneri in Thames river water. J Environ Chem Eng 6:19\u201327. https:\/\/doi.org\/10.1016\/j.jece.2017.11.069","journal-title":"J Environ Chem Eng"},{"key":"12171_CR49","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.ibiod.2012.05.018","volume":"73","author":"I Mathe","year":"2012","unstructured":"Mathe I, Benedek T, T\u00e1ncsics A et al (2012) Diversity, activity, antibiotic and heavy metal resistance of bacteria from petroleum hydrocarbon contaminated soils located in Harghita County (Romania). Int Biodeterior Biodegrad 73:41\u201349. https:\/\/doi.org\/10.1016\/j.ibiod.2012.05.018","journal-title":"Int Biodeterior Biodegrad"},{"key":"12171_CR50","doi-asserted-by":"crossref","unstructured":"Maurya AP, Rajkumari J, Bhattacharjee A, Pandey P (2020) Development, spread and persistence of antibiotic resistance genes (ARGs) in the soil microbiomes through co-selection. Rev Environ Health 1","DOI":"10.1515\/reveh-2020-0035"},{"key":"12171_CR51","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1111\/1462-2920.12368","volume":"16","author":"C Molina-Santiago","year":"2014","unstructured":"Molina-Santiago C, Daddaoua A, Fillet S, Duque E, Ramos JL (2014) Interspecies signalling: Pseudomonas putida efflux pump TtgGHI is activated by indole to increase antibiotic resistance. Environ Microbiol 16:1267\u20131281. https:\/\/doi.org\/10.1111\/1462-2920.12368","journal-title":"Environ Microbiol"},{"key":"12171_CR52","unstructured":"Montano-Soto M T, Garza-Ocanas L (2014) Health effects due to exposure to polycyclic aromatic hydrocarbons from the petroleum refining industry. Med Univ 16:136\u2013140"},{"key":"12171_CR53","doi-asserted-by":"publisher","first-page":"193","DOI":"10.33073\/PJM-2019-019","volume":"68","author":"F Muccee","year":"2019","unstructured":"Muccee F, Ejaz S (2019) An investigation of petrol metabolizing bacteria isolated from contaminated soil samples collected from various fuel stations. Pol J Microbiol 68:193\u2013201. https:\/\/doi.org\/10.33073\/PJM-2019-019","journal-title":"Pol J Microbiol"},{"key":"12171_CR54","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1111\/1462-2920.12631","volume":"17","author":"J Nesme","year":"2015","unstructured":"Nesme J, Simonet P (2015) Minireview The soil resistome: a critical review on antibiotic resistance origins , ecology and dissemination potential in telluric bacteria. Environ Microbiol 17:913\u2013930. https:\/\/doi.org\/10.1111\/1462-2920.12631","journal-title":"Environ Microbiol"},{"key":"12171_CR55","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1093\/jac\/dki245","volume":"56","author":"P Nordmann","year":"2005","unstructured":"Nordmann P, Poirel L (2005) Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae. J Antimicrob Chemother 56:463\u2013469. https:\/\/doi.org\/10.1093\/jac\/dki245","journal-title":"J Antimicrob Chemother"},{"key":"12171_CR56","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1126\/science.aah4993","volume":"354","author":"NM Reid","year":"2016","unstructured":"Reid NM, Proestou DA, Clark BW et al (2016) The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. Science (80- ) 354:1305\u20131308. https:\/\/doi.org\/10.1126\/science.aah4993","journal-title":"Science (80- )"},{"key":"12171_CR57","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1007\/s10311-018-0791-y","volume":"17","author":"K Rodgers","year":"2019","unstructured":"Rodgers K, McLellan I, Peshkur T, Williams R, Tonner R, Hursthouse AS, Knapp CW, Henriquez FL (2019) Can the legacy of industrial pollution influence antimicrobial resistance in estuarine sediments? Environ Chem Lett 17:595\u2013607","journal-title":"Environ Chem Lett"},{"key":"12171_CR58","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1023\/A:1016362819746","volume":"18","author":"S Roy","year":"2002","unstructured":"Roy S, Hens D, Biswas D, Biswas D, Kumar R (2002) Survey of petroleum-degrading bacteria in coastal waters of Sunderban Biosphere Reserve. World J Microbiol Biotechnol 18:575\u2013581. https:\/\/doi.org\/10.1023\/A:1016362819746","journal-title":"World J Microbiol Biotechnol"},{"key":"12171_CR59","doi-asserted-by":"publisher","first-page":"399","DOI":"10.3389\/fmicb.2012.00399","volume":"3","author":"C Seiler","year":"2012","unstructured":"Seiler C, Berendonk TU (2012) Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture. Front Microbiol 3:399. https:\/\/doi.org\/10.3389\/fmicb.2012.00399","journal-title":"Front Microbiol"},{"key":"12171_CR60","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.ibiod.2007.12.003","volume":"62","author":"X Sheng","year":"2008","unstructured":"Sheng X, Chen X, He L (2008) Characteristics of an endophytic pyrene-degrading bacterium of Enterobacter sp. 12J1 from Allium macrostemon Bunge. Int Biodeterior Biodegrad 62:88\u201395","journal-title":"Int Biodeterior Biodegrad"},{"key":"12171_CR61","doi-asserted-by":"publisher","first-page":"1794","DOI":"10.1111\/j.1365-294X.2012.05538.x","volume":"21","author":"S Shokralla","year":"2012","unstructured":"Shokralla S, Spall J, Gibson J, Hajibabaei M (2012) Next-generation sequencing technologies for environmental DNA research. Mol Ecol 21:1794\u20131805. https:\/\/doi.org\/10.1111\/j.1365-294X.2012.05538.x","journal-title":"Mol Ecol"},{"key":"12171_CR62","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1021\/acs.est.8b05750","volume":"53","author":"W Shou","year":"2019","unstructured":"Shou W, Kang F, Huang S, Yan C, Zhou J, Wang Y (2019) Substituted aromatic-facilitated dissemination of mobile antibiotic resistance genes via an antihydrolysis mechanism across an extracellular polymeric substance permeable barrier. Environ Sci Technol 53:604\u2013613. https:\/\/doi.org\/10.1021\/acs.est.8b05750","journal-title":"Environ Sci Technol"},{"key":"12171_CR63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2323\/jgam.57.1","volume":"57","author":"MM Stancu","year":"2011","unstructured":"Stancu MM, Grifoll M (2011) Multidrug resistance in hydrocarbon-tolerant Gram-positive and Gram-negative bacteria. J Gen Appl Microbiol 57:1\u201318. https:\/\/doi.org\/10.2323\/jgam.57.1","journal-title":"J Gen Appl Microbiol"},{"key":"12171_CR64","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1099\/jmm.0.009142-0","volume":"58","author":"T Strateva","year":"2009","unstructured":"Strateva T, Yordanov D (2009) Pseudomonas aeruginosa-a phenomenon of bacterial resistance. J Med Microbiol 58:1133\u20131148","journal-title":"J Med Microbiol"},{"key":"12171_CR65","doi-asserted-by":"publisher","unstructured":"Su S, Li C, Yang J, Xu Q, Qiu Z, Xue B, Wang S, Zhao C, Xiao Z, Wang J, Shen Z (2020) Distribution of antibiotic resistance genes in three different natural water bodies-a lake, river and sea. Int J Environ Res Public Health 17. https:\/\/doi.org\/10.3390\/ijerph17020552","DOI":"10.3390\/ijerph17020552"},{"key":"12171_CR66","doi-asserted-by":"publisher","first-page":"853","DOI":"10.5846\/stxb201210091393","volume":"34","author":"K Sun","year":"2014","unstructured":"Sun K, Liu J, Li X, Ling W (2014) Isolation, identification, and performance of two pyrene-degrading endophytic bacteria. Shengtai Xuebao\/ Acta Ecol Sin 34:853\u2013861. https:\/\/doi.org\/10.5846\/stxb201210091393","journal-title":"Shengtai Xuebao\/ Acta Ecol Sin"},{"key":"12171_CR67","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.jhazmat.2015.06.065","volume":"300","author":"MM Sun","year":"2015","unstructured":"Sun MM, Ye M, Wu J, Feng Y, Shen F, Tian D, Liu K, Hu F, Li H, Jiang X, Yang L, Kengara FO (2015) Impact of bioaccessible pyrene on the abundance of antibiotic resistance genes during Sphingobium sp.-and sophorolipid-enhanced bioremediation in soil. J Hazard Mater 300:121\u2013128","journal-title":"J Hazard Mater"},{"key":"12171_CR68","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/srep11981","volume":"5","author":"D Versluis","year":"2015","unstructured":"Versluis D, D\u2019Andrea MM, Ramiro Garcia J, Leimena MM, Hugenholtz F, Zhang J, \u00d6zt\u00fcrk B, Nylund L, Sipkema D, Schaik W, de Vos WM, Kleerebezem M, Smidt H, Passel MWJ (2015) Mining microbial metatranscriptomes for expression of antibiotic resistance genes under natural conditions. Sci Rep 5:1\u201310. https:\/\/doi.org\/10.1038\/srep11981","journal-title":"Sci Rep"},{"key":"12171_CR69","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1016\/j.envpol.2017.07.067","volume":"231","author":"J Wang","year":"2017","unstructured":"Wang J, Wang J, Zhao Z, Chen J, Lu H, Liu G, Zhou J, Guan X (2017) PAHs accelerate the propagation of antibiotic resistance genes in coastal water microbial community. Environ Pollut 231:1145\u20131152. https:\/\/doi.org\/10.1016\/j.envpol.2017.07.067","journal-title":"Environ Pollut"},{"key":"12171_CR70","doi-asserted-by":"crossref","unstructured":"Wellington EMH, Boxall ABA, Cross P, et al (2013) The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria. Lancet Infect Dis 13:155\u2013165","DOI":"10.1016\/S1473-3099(12)70317-1"},{"key":"12171_CR71","doi-asserted-by":"publisher","first-page":"12602","DOI":"10.1021\/acs.est.6b02138","volume":"50","author":"WY Xie","year":"2016","unstructured":"Xie WY, McGrath SP, Su JQ et al (2016) Long-term impact of field applications of sewage sludge on soil antibiotic resistome. Environ Sci Technol 50:12602\u201312611. https:\/\/doi.org\/10.1021\/acs.est.6b02138","journal-title":"Environ Sci Technol"},{"key":"12171_CR72","doi-asserted-by":"publisher","unstructured":"Yao X, Tao F, Zhang K, Tang H, Xu P (2017) Multiple roles for two efflux pumps in the polycyclic aromatic hydrocarbon-degrading Pseudomonas putida strain B6-2 (DSM 28064). Appl Environ Microbiol 83. https:\/\/doi.org\/10.1128\/AEM.01882-17","DOI":"10.1128\/AEM.01882-17"},{"key":"12171_CR73","doi-asserted-by":"publisher","first-page":"1548248","DOI":"10.1080\/16512235.2018.1548248","volume":"29","author":"S Yazdankhah","year":"2018","unstructured":"Yazdankhah S, Skjerve E, Wasteson Y (2018) Microbial ecology in health and disease antimicrobial resistance due to the content of potentially toxic metals in soil and fertilizing products. Microb Ecol Health Dis 29:1548248. https:\/\/doi.org\/10.1080\/16512235.2018.1548248","journal-title":"Microb Ecol Health Dis"},{"key":"12171_CR74","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1038\/ismej.2013.163","volume":"8","author":"E Yergeau","year":"2014","unstructured":"Yergeau E, Sanschagrin S, Maynard C, St-Arnaud M, Greer CW (2014) Microbial expression profiles in the rhizosphere of willows depend on soil contamination. ISME J 8:344\u2013358. https:\/\/doi.org\/10.1038\/ismej.2013.163","journal-title":"ISME J"},{"key":"12171_CR75","doi-asserted-by":"publisher","first-page":"23753","DOI":"10.1007\/s11356-017-0032-0","volume":"24","author":"ZC Zhou","year":"2017","unstructured":"Zhou ZC, Zheng J, Wei YY, Chen T, Dahlgren RA, Shang X, Chen H (2017) Antibiotic resistance genes in an urban river as impacted by bacterial community and physicochemical parameters. Environ Sci Pollut Res 24:23753\u201323762. https:\/\/doi.org\/10.1007\/s11356-017-0032-0","journal-title":"Environ Sci Pollut Res"},{"key":"12171_CR76","doi-asserted-by":"publisher","first-page":"16270","DOI":"10.1038\/nmicrobiol.2016.270","volume":"2","author":"Y-G Zhu","year":"2017","unstructured":"Zhu Y-G, Zhao Y, Li B, Huang CL, Zhang SY, Yu S, Chen YS, Zhang T, Gillings MR, Su JQ (2017) Continental-scale pollution of estuaries with antibiotic resistance genes. Nat Microbiol 2:16270. https:\/\/doi.org\/10.1038\/nmicrobiol.2016.270","journal-title":"Nat Microbiol"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-12171-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11356-020-12171-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-020-12171-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T15:25:22Z","timestamp":1614612322000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11356-020-12171-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,4]]},"references-count":76,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["12171"],"URL":"https:\/\/doi.org\/10.1007\/s11356-020-12171-3","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,4]]},"assertion":[{"value":"6 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors gave their consent to publish the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}