{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:46:14Z","timestamp":1788263174811,"version":"build-2803163510"},"reference-count":95,"publisher":"Springer Science and Business Media LLC","issue":"23","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s11356-021-12693-4","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:01:46Z","timestamp":1612915306000},"page":"29535-29550","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["The effects of dietary clinoptilolite and chitosan nanoparticles on growth, body composition, haemato-biochemical parameters, immune responses, and antioxidative status of Nile tilapia exposed to imidacloprid"],"prefix":"10.1007","volume":"28","author":[{"given":"Nahla E. M.","family":"Ismael","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samah A. A.","family":"Abd El-hameed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amany M.","family":"Salama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed A. E.","family":"Naiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8761-1493","authenticated-orcid":false,"given":"Hany M. R.","family":"Abdel-Latif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"key":"12693_CR1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.aquaculture.2018.11.014","volume":"501","author":"FS Abd El-Naby","year":"2019","unstructured":"Abd El-Naby FS, Naiel MAE, Al-Sagheer AA, Negm SS (2019) Dietary chitosan nanoparticles enhance the growth, production performance, and immunity in Oreochromis niloticus. Aquaculture 501:82\u201389","journal-title":"Aquaculture"},{"key":"12693_CR2","doi-asserted-by":"crossref","first-page":"734577","DOI":"10.1016\/j.aquaculture.2019.734577","volume":"515","author":"AS Abd El-Naby","year":"2020","unstructured":"Abd El-Naby AS, Al-Sagheer AA, Negm SS, Naiel MAE (2020) Dietary combination of chitosan nanoparticle and thymol affects feed utilization, digestive enzymes, antioxidant status, and intestinal morphology of Oreochromis niloticus. Aquaculture 515:734577","journal-title":"Aquaculture"},{"key":"12693_CR3","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.etap.2019.03.016","volume":"69","author":"MM Abdel-Daim","year":"2019","unstructured":"Abdel-Daim MM, Eissa IAM, Abdeen A, Abdel-Latif HMR, Ismail M, Dawood MAO, Hassan AM (2019) Lycopene and resveratrol ameliorate zinc oxide nanoparticles-induced oxidative stress in Nile tilapia, Oreochromis niloticus. Environ Toxicol Pharmacol 69:44\u201350","journal-title":"Environ Toxicol Pharmacol"},{"key":"12693_CR4","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/raq.12326","volume":"12","author":"HM Abdel-Ghany","year":"2020","unstructured":"Abdel-Ghany HM, Salem ME-S (2020) Effects of dietary chitosan supplementation on farmed fish; a review. Rev Aquac 12:438\u2013452","journal-title":"Rev Aquac"},{"key":"12693_CR5","doi-asserted-by":"crossref","unstructured":"Abdel-Latif HMR, Abdel-Tawwab M, Dawood MAO, Menanteau-Ledouble S, El-Matbouli M (2020a) Benefits of dietary butyric acid, sodium butyrate, and their protected forms in aquafeeds: a review. Reviews in Fisheries Science & Aquaculture:1\u201328","DOI":"10.1080\/23308249.2020.1758899"},{"key":"12693_CR6","volume":"526","author":"HMR Abdel-Latif","year":"2020","unstructured":"Abdel-Latif HMR, Abdel-Tawwab M, Khafaga AF, Dawood MAO (2020b) Dietary oregano essential oil improved the growth performance via enhancing the intestinal morphometry and hepato-renal functions of common carp (Cyprinus carpio L.) fingerlings. Aquaculture 526:735432","journal-title":"Aquaculture"},{"key":"12693_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsi.2020.05.056","volume":"104","author":"HMR Abdel-Latif","year":"2020","unstructured":"Abdel-Latif HMR, Abdel-Tawwab M, Khafaga AF, Dawood MAO (2020c) Dietary origanum essential oil improved antioxidative status, immune-related genes, and resistance of common carp (Cyprinus carpio L.) to Aeromonas hydrophila infection. Fish Shellfish Immunol 104:1\u20137","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR8","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.fsi.2019.02.063","volume":"88","author":"M Abdel-Tawwab","year":"2019","unstructured":"Abdel-Tawwab M, Razek NA, Abdel-Rahman AM (2019) Immunostimulatory effect of dietary chitosan nanoparticles on the performance of Nile tilapia, Oreochromis niloticus (L.). Fish Shellfish Immunol 88:254\u2013258","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0959-8030(92)90066-7","volume":"2","author":"JB Alexander","year":"1992","unstructured":"Alexander JB, Ingram GA (1992) Noncellular nonspecific defence mechanisms of fish. Annu Rev Fish Dis 2:249\u2013279","journal-title":"Annu Rev Fish Dis"},{"key":"12693_CR10","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.fsi.2017.08.021","volume":"70","author":"S Alinezhad","year":"2017","unstructured":"Alinezhad S, Faridi M, Falahatkar B, Nabizadeh R, Davoodi D (2017) Effects of nanostructured zeolite and aflatoxin B1 in growth performance, immune parameters and pathological conditions of rainbow trout Oncorhynchus mykiss. Fish Shellfish Immunol 70:648\u2013655","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s11270-019-4256-0","volume":"230","author":"JHP Am\u00e9rico-Pinheiro","year":"2019","unstructured":"Am\u00e9rico-Pinheiro JHP, da Cruz C, Aguiar MM, Torres NH, Ferreira LFR, Machado-Neto JG (2019) Sublethal effects of imidacloprid in hematological parameters of tilapia (Oreochromis niloticus). Water Air Soil Pollut 230:193","journal-title":"Water Air Soil Pollut"},{"key":"12693_CR12","unstructured":"Anderson D, Siwicki A (1995) Basic haematology and serology for fish health programs"},{"key":"12693_CR13","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.4236\/jep.2015.612118","volume":"6","author":"Y Ansoar-Rodr\u00edguez","year":"2015","unstructured":"Ansoar-Rodr\u00edguez Y, Christofoletti CA, Marcato AC, Correia JE, Bueno OC, Malaspina O, Fontanetti CS (2015) Genotoxic potential of the insecticide imidacloprid in a non-target organism (Oreochromis niloticus-Pisces). J Environ Prot 6:1360","journal-title":"J Environ Prot"},{"key":"12693_CR14","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1080\/03601234.2016.1240559","volume":"51","author":"Y Ansoar-Rodr\u00edguez","year":"2016","unstructured":"Ansoar-Rodr\u00edguez Y, Christofoletti CA, Correia JE, de Souza RB, Moreira-de-Sousa C, Marcato ACC, Bueno OC, Malaspina O, Silva-Zacarin ECM, Fontanetti CS (2016) Liver alterations in Oreochromis niloticus (Pisces) induced by insecticide imidacloprid: Histopathology and heat shock protein in situ localization. Journal of Environmental Science and Health, Part B 51:881\u2013887","journal-title":"Journal of Environmental Science and Health, Part B"},{"key":"12693_CR15","first-page":"1028","volume-title":"Association of Official Analytical Chemists International - official methods of analysis, 15th edn (edited by. K. Helrich)","author":"AOAC","year":"1990","unstructured":"AOAC (1990) Association of Official Analytical Chemists International - official methods of analysis, 15th edn (edited by. K. Helrich). Association of Official Analytical Chemists Inc, Arlington, VA, pp 1028\u20131039"},{"key":"12693_CR16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2754\/avb201685040349","volume":"85","author":"J Barto\u0148kov\u00e1","year":"2017","unstructured":"Barto\u0148kov\u00e1 J, Hyr\u0161l P, Vojtek L (2017) Glucose determination in fish plasma by two different moderate methods. Acta Vet Brno 85:349\u2013353","journal-title":"Acta Vet Brno"},{"key":"12693_CR17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1577\/1548-8659(1982)44[19:ARBCIT]2.0.CO;2","volume":"44","author":"CE Bower","year":"1982","unstructured":"Bower CE, Turner DT (1982) Ammonia removal by clinoptilolite in the transport of ornamental freshwater fishes. The Progressive Fish-Culturist 44:19\u201323","journal-title":"The Progressive Fish-Culturist"},{"key":"12693_CR18","unstructured":"Boyd CE, Tucker CS (2012) Pond aquaculture water quality management. Springer Science & Business Media"},{"key":"12693_CR19","first-page":"7","volume-title":"Hematology. Principles and Procedures","author":"BA Brown","year":"1988","unstructured":"Brown BA (1988) Routine hematology procedures. In: Brown BA (ed) Hematology. Principles and Procedures. Leo and Fabiger, Philadelphia, Pennsylvania, USA, pp 7\u2013122"},{"key":"12693_CR20","volume-title":"Carleton's histological technique","author":"H Carleton","year":"1980","unstructured":"Carleton H, Drury R, Wallington E (1980) Carleton's histological technique. Oxford University Press, USA"},{"key":"12693_CR21","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1208\/s12249-010-9561-2","volume":"12","author":"A Chaudhury","year":"2011","unstructured":"Chaudhury A, Das S (2011) Recent Advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents. AAPS PharmSciTech 12:10\u201320. https:\/\/doi.org\/10.1208\/s12249-010-9561-2","journal-title":"AAPS PharmSciTech"},{"key":"12693_CR22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13104-018-3162-7","volume":"11","author":"B Chen","year":"2018","unstructured":"Chen B, Li J, Borgens RB (2018) Neuroprotection by chitosan nanoparticles in oxidative stress-mediated injury. BMC research notes 11:1\u20137","journal-title":"BMC research notes"},{"key":"12693_CR23","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1111\/anu.13094","volume":"26","author":"X Chen","year":"2020","unstructured":"Chen X, Zhang Z, Fernandes JMO, Gao Y, Yin P, Liu Y, Tian L, Xie S, Niu J (2020) Beneficial effects on growth, haematic indicators, immune status, antioxidant function and gut health in Juvenile Nile tilapia (Oreochromis niloticus) by dietary administration of a multi-strain probiotic. Aquac Nutr 26:1369\u20131382","journal-title":"Aquac Nutr"},{"key":"12693_CR24","first-page":"550","volume":"50","author":"HB Collier","year":"1944","unstructured":"Collier HB (1944) Standardization of blood haemoglobin determinations. Can Med Assoc J 50:550\u2013552","journal-title":"Can Med Assoc J"},{"key":"12693_CR25","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ntt.2015.04.006","volume":"49","author":"EB Crosby","year":"2015","unstructured":"Crosby EB, Bailey JM, Oliveri AN, Levin ED (2015) Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish. Neurotoxicol Teratol 49:81\u201390","journal-title":"Neurotoxicol Teratol"},{"key":"12693_CR26","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/BF01030998","volume":"13","author":"RG Cuero","year":"1991","unstructured":"Cuero RG, Osuji G, Washington A (1991) N-carboxymethylchitosan inhibition of aflatoxin production: role of zinc. Biotechnol Lett 13:441\u2013444","journal-title":"Biotechnol Lett"},{"key":"12693_CR27","volume-title":"Practical Haematology","author":"JV Dacie","year":"1984","unstructured":"Dacie JV, Lewis SM (1984) Practical Haematology, 6th edn. Churchill Livingstone, London, UK","edition":"6"},{"key":"12693_CR28","doi-asserted-by":"crossref","unstructured":"Dawood MA, Gewaily MS, Soliman AA, Shukry M, Amer AA, Younis EM, Abdel-Warith A-WA, Van Doan H, Saad AH, Aboubakr M (2020a): Marine-derived chitosan nanoparticles improved the intestinal histo-morphometrical features in association with the health and immune response of grey mullet (Liza ramada). Marine Drugs 18, 611","DOI":"10.3390\/md18120611"},{"key":"12693_CR29","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.fsi.2020.04.059","volume":"102","author":"MAO Dawood","year":"2020","unstructured":"Dawood MAO, El-Salam Metwally A, Elkomy AH, Gewaily MS, Abdo SE, Abdel-Razek MAS, Soliman AA, Amer AA, Abdel-Razik NI, Abdel-Latif HMR, Paray BA (2020) The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia. Fish Shellfish Immunol 102:316\u2013325","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR30","doi-asserted-by":"crossref","unstructured":"Dawood MAO, Metwally AE-S, El-Sharawy ME, Ghozlan AM, Abdel-Latif HMR, Van Doan H, Ali MAM (2020c): The influences of ferulic acid on the growth performance, haemato-immunological responses, and immune-related genes of Nile tilapia (Oreochromis niloticus) exposed to heat stress. Aquaculture 525, 735320","DOI":"10.1016\/j.aquaculture.2020.735320"},{"key":"12693_CR31","doi-asserted-by":"publisher","first-page":"2511","DOI":"10.1111\/raq.12455","volume":"12","author":"MAO Dawood","year":"2020","unstructured":"Dawood MAO, Abdel-Tawwab M, Abdel-Latif HMR (2020d) Lycopene reduces the impacts of aquatic environmental pollutants and physical stressors in fish. Rev Aquacult 12:2511\u20132526. https:\/\/doi.org\/10.1111\/raq.12455","journal-title":"Rev Aquacult"},{"key":"12693_CR33","unstructured":"Dewangan G, Mishra A, Mandal TK (2016) A simple RP-HPLC method for determining imidacloprid residues in goat tissues. Biomed Res 27 (1)"},{"key":"12693_CR34","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0990-7440(98)89004-9","volume":"11","author":"J Dias","year":"1998","unstructured":"Dias J, Huelvan C, Dinis MT, M\u00e9tailler R (1998) Influence of dietary bulk agents (silica, cellulose and a natural zeolite) on protein digestibility, growth, feed intake and feed transit time in European seabass (Dicentrarchus labrax) juveniles. Aquat Living Resour 11:219\u2013226","journal-title":"Aquat Living Resour"},{"key":"12693_CR35","unstructured":"Dytham C (2011) Choosing and using statistics: a biologist\u2019s guide. John Wiley & Sons"},{"issue":"1","key":"12693_CR36","first-page":"30","volume":"11","author":"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)","year":"2013","unstructured":"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) (2013) Scientific Opinion on the safety and efficacy of clinoptilolite of sedimentary origin for all animal species. EFSA J 11(1):30\u201339","journal-title":"EFSA J"},{"key":"12693_CR37","first-page":"101","volume":"1","author":"AE Ellis","year":"1990","unstructured":"Ellis AE (1990) Lysozyme assays. Techniques Fish Immunol 1:101\u2013103","journal-title":"Techniques Fish Immunol"},{"key":"12693_CR38","first-page":"348","volume-title":"Tilapia Culture","author":"A-F El-Sayed","year":"2020","unstructured":"El-Sayed A-F (2020) Tilapia Culture, 2nd edn. Elsevier\/Academic Press, Londonand Oxford, UK and San Diego, CA, p 348","edition":"2"},{"key":"12693_CR39","first-page":"961","volume":"2","author":"JC Eya","year":"2008","unstructured":"Eya JC, Parsons A, Haile I, Jagidi P (2008) Effects of dietary zeolites (bentonite and mordenite) on the performance juvenile rainbow trout Onchorhynchus myskis. Aust J Basic Appl Sci 2:961\u2013967","journal-title":"Aust J Basic Appl Sci"},{"key":"12693_CR40","doi-asserted-by":"crossref","DOI":"10.1016\/j.reactfunctpolym.2019.104459","volume":"147","author":"LA Frank","year":"2020","unstructured":"Frank LA, Onzi GR, Morawski AS, Pohlmann AR, Guterres SS, Contri RV (2020) Chitosan as a coating material for nanoparticles intended for biomedical applications. React Funct Polym 147:104459","journal-title":"React Funct Polym"},{"key":"12693_CR41","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.foodchem.2016.02.098","volume":"207","author":"J Gan","year":"2016","unstructured":"Gan J, Lv L, Peng J, Li J, Xiong Z, Chen D, He L (2016) Multi-residue method for the determination of organofluorine pesticides in fish tissue by liquid chromatography triple quadrupole tandem mass spectrometry. Food Chem 207:195\u2013204","journal-title":"Food Chem"},{"key":"12693_CR42","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/raq.12148","volume":"10","author":"Z Ghasemi","year":"2018","unstructured":"Ghasemi Z, Sourinejad I, Kazemian H, Rohani S (2018) Application of zeolites in aquaculture industry: a review. Rev Aquac 10:75\u201395","journal-title":"Rev Aquac"},{"key":"12693_CR43","doi-asserted-by":"crossref","first-page":"636","DOI":"10.3923\/ajava.2011.636.641","volume":"6","author":"F Ghiasi","year":"2011","unstructured":"Ghiasi F, Mirzargar S, Badakhshan H, Amoli JS (2011) Influence of Iranian natural zeolite on accumulation of cadmium in Cyprinus carpio tissues following exposure to low concentration of cadmium. Asian journal of Animal and Veterinary Advances 6:636\u2013641","journal-title":"Asian journal of Animal and Veterinary Advances"},{"key":"12693_CR44","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11270-019-4366-8","volume":"231","author":"A\u00c7 G\u00fcnal","year":"2020","unstructured":"G\u00fcnal A\u00c7, Erkmen B, Pa\u00e7al E, Arslan P, Yildirim Z, Erko\u00e7 F (2020) Sub-lethal effects of imidacloprid on Nile tilapia (Oreochromis niloticus). Water Air Soil Pollut 231:4","journal-title":"Water Air Soil Pollut"},{"key":"12693_CR45","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s12011-011-9191-x","volume":"145","author":"X-Y Han","year":"2012","unstructured":"Han X-Y, Du W-L, Huang Q-C, Xu Z-R, Wang Y-Z (2012) Changes in small intestinal morphology and digestive enzyme activity with oral administration of copper-loaded chitosan nanoparticles in rats. Biol Trace Elem Res 145:355\u2013360","journal-title":"Biol Trace Elem Res"},{"key":"12693_CR46","doi-asserted-by":"crossref","first-page":"735123","DOI":"10.1016\/j.aquaculture.2020.735123","volume":"523","author":"MS Hassaan","year":"2020","unstructured":"Hassaan MS, Nssar KM, Mohammady EY, Amin A, Tayel SI, El-Haroun ER (2020) Nano-zeolite efficiency to mitigate the aflatoxin B1 (AFB1) toxicity: Effects on growth, digestive enzymes, antioxidant, DNA damage and bioaccumulation of AFB1 residues in Nile tilapia (Oreochromis niloticus). Aquaculture 523:735123","journal-title":"Aquaculture"},{"key":"12693_CR47","volume-title":"Colorimetric determination of total protein. clinical chemistry","author":"R Henry","year":"1964","unstructured":"Henry R (1964) Colorimetric determination of total protein. clinical chemistry. Harper and Row Publ, New York, USA"},{"key":"12693_CR48","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.envpol.2017.12.036","volume":"233","author":"X Hong","year":"2018","unstructured":"Hong X, Zhao X, Tian X, Li J, Zha J (2018) Changes of hematological and biochemical parameters revealed genotoxicity and immunotoxicity of neonicotinoids on Chinese rare minnows (Gobiocypris rarus). Environ Pollut 233:862\u2013871","journal-title":"Environ Pollut"},{"key":"12693_CR49","doi-asserted-by":"crossref","unstructured":"Hoseinifar SH, Yousefi S, Van Doan H, Ashouri G, Gioacchini G, Maradonna F, Carnevali O (2020) Oxidative stress and antioxidant defense in fish: the implications of probiotic, prebiotic, and synbiotics. Reviews in Fisheries Science & Aquaculture:1\u201320","DOI":"10.1080\/23308249.2020.1795616"},{"key":"12693_CR50","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1111\/anu.12101","volume":"20","author":"CH Hu","year":"2014","unstructured":"Hu CH, Xiao K, Jiao LF, Song J (2014) Effects of zinc oxide supported on zeolite on growth performance, intestinal barrier function and digestive enzyme activities of Nile tilapia. Aquac Nutr 20:486\u2013493","journal-title":"Aquac Nutr"},{"key":"12693_CR51","first-page":"257","volume":"2","author":"S Ibrahim","year":"2008","unstructured":"Ibrahim S, Shalloof K, Salama H (2008) Effect of environmental conditions of Abu-Zabal Lake on some biological, histological and quality aspects of fish. Global Veterinaria 2:257\u2013270","journal-title":"Global Veterinaria"},{"key":"12693_CR52","first-page":"253","volume":"9","author":"IH Ibrahim","year":"2016","unstructured":"Ibrahim IH, Fath El-Bab AF, Shehab El-Din MT (2016) Evaluation of natural zeolite (clinoptilolite) as a feed additive in Nile tilapia fish diets and its influences on growth performance, genetic traits and fish health. Abbassa International Journal of Aquaculture 9:253\u2013287","journal-title":"Abbassa International Journal of Aquaculture"},{"key":"12693_CR53","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.fsi.2016.02.019","volume":"51","author":"S Jawahar","year":"2016","unstructured":"Jawahar S, Nafar A, Vasanth K, Musthafa MS, Arockiaraj J, Balasundaram C, Harikrishnan R (2016) Dietary supplementation of zeolite on growth performance, immunological role, and disease resistance in Channa striatus against Aphanomyces invadans. Fish Shellfish Immunol 51:161\u2013169","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR54","volume-title":"The use of natural zeolite (Clinoptilolite) in gilthead sea brem (Sparus aurata) culture","author":"M Kanyilmaz","year":"2012","unstructured":"Kanyilmaz M (2012) The use of natural zeolite (Clinoptilolite) in gilthead sea brem (Sparus aurata) culture. Cukurova University (with english abstract, PhD Thesis)."},{"key":"12693_CR55","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.anifeedsci.2014.09.023","volume":"200","author":"M Kany\u0131lmaz","year":"2015","unstructured":"Kany\u0131lmaz M, Tekelio\u011flu N, Sevgili H, Uysal R, Aksoy A (2015) Effects of dietary zeolite (clinoptilolite) levels on growth performance, feed utilization and waste excretions by gilthead sea bream juveniles (Sparus aurata). Anim Feed Sci Technol 200:66\u201375","journal-title":"Anim Feed Sci Technol"},{"key":"12693_CR56","first-page":"495","volume":"13","author":"A Khodanazary","year":"2013","unstructured":"Khodanazary A, Boldaji F, Tatar A, Dastar B (2013) Effects of dietary zeolite and perlite supplementations on growth and nutrient utilization performance, and some serum variables in Common carp (Cyprinus carpio). Turk J Fish Aquat Sci 13:495\u2013501","journal-title":"Turk J Fish Aquat Sci"},{"key":"12693_CR57","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.foodchem.2006.01.038","volume":"101","author":"KW Kim","year":"2007","unstructured":"Kim KW, Thomas RL (2007) Antioxidative activity of chitosans with varying molecular weights. Food Chem 101:308\u2013313","journal-title":"Food Chem"},{"key":"12693_CR58","unstructured":"Klontz G (1994) Fish hematology. In: Stolen JS, Fletcher TC, Rowley AF, Kelikoff TC, Kaatari SL, Smith SA (eds) Techniques in Fish Immunology. SOS Publications, Fair Haven, New Jersey, USA, p 3"},{"key":"12693_CR59","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.3390\/molecules24081517","volume":"24","author":"A Mastinu","year":"2019","unstructured":"Mastinu A, Kumar A, Maccarinelli G, Bonini SA, Premoli M, Aria F, Gianoncelli A, Memo M (2019) Zeolite clinoptilolite: therapeutic virtues of an ancient mineral. Molecules 24:1517","journal-title":"Molecules"},{"key":"12693_CR60","unstructured":"Mintova S (2019) Control of properties of nanosized zeolites, 20th Brazilian Catalysis Society (CBCAT)"},{"key":"12693_CR61","first-page":"39","volume":"23","author":"M Mishra","year":"2009","unstructured":"Mishra M, Jain SK (2009) Effect of natural ion exchanger Chabazite for remediation of lead toxicity: an experimental study in teleost fish Heteropneustes fossilis. Asian J Exp Sci 23:39\u201344","journal-title":"Asian J Exp Sci"},{"key":"12693_CR62","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1292\/jvms.67.51","volume":"67","author":"T Mori","year":"2005","unstructured":"Mori T, Murakami M, Okumura M, Kadosawa T, Uede T, Fujinaga T (2005) Mechanism of macrophage activation by chitin derivatives. J Vet Med Sci 67:51\u201356","journal-title":"J Vet Med Sci"},{"key":"12693_CR63","doi-asserted-by":"publisher","first-page":"2250","DOI":"10.1111\/raq.12432","volume":"12","author":"MAE Naiel","year":"2020","unstructured":"Naiel MAE, Shehata AM, Negm SS, Abd El-Hack ME, Amer MS, Khafaga AF, Bin-Jumah M, Allam AA (2020a) The new aspects of using some safe feed additives on alleviated imidacloprid toxicity in farmed fish: a review. Rev Aquacult 12:2250\u20132267. https:\/\/doi.org\/10.1111\/raq.12432","journal-title":"Rev Aquacult"},{"key":"12693_CR64","doi-asserted-by":"crossref","first-page":"735219","DOI":"10.1016\/j.aquaculture.2020.735219","volume":"523","author":"MAE Naiel","year":"2020","unstructured":"Naiel MAE, Ismael NEM, Abd El-hameed SAA, Amer MS (2020b) The antioxidative and immunity roles of chitosan nanoparticle and vitamin C-supplemented diets against imidacloprid toxicity on Oreochromis niloticus. Aquaculture 523:735219","journal-title":"Aquaculture"},{"key":"12693_CR65","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/raq.12014","volume":"5","author":"W-K Ng","year":"2013","unstructured":"Ng W-K, Romano N (2013) A review of the nutrition and feeding management of farmed tilapia throughout the culture cycle. Rev Aquac 5:220\u2013254","journal-title":"Rev Aquac"},{"key":"12693_CR66","doi-asserted-by":"crossref","unstructured":"Ngo D-H, Kim S-K (2014) Chapter Two - Antioxidant effects of chitin, chitosan, and their derivatives. In: Kim S-K (ed) Advances in Food and Nutrition Research. Academic Press, pp 15\u201331","DOI":"10.1016\/B978-0-12-800268-1.00002-0"},{"key":"12693_CR67","first-page":"171","volume":"3","author":"M Nicula","year":"2010","unstructured":"Nicula M, B\u0103n\u0103\u0163ean-Dunea I, Gergen I, H\u0103rm\u0103nescu M, Simiz E, P\u0103truic\u0103 S, Polen T, Marcu A, Lunca M, Szucs S (2010) Effect of natural zeolite on reducing tissue bioaccumulation and cadmium antagonism related to some mineral micro-and macronutrients in Prussian carp (Carassius gibelio). Aquaculture, Aquarium, Conservation & Legislation 3:171\u2013179","journal-title":"Aquaculture, Aquarium, Conservation & Legislation"},{"key":"12693_CR68","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.fsi.2018.03.010","volume":"76","author":"C Nikapitiya","year":"2018","unstructured":"Nikapitiya C, Dananjaya SHS, De Silva BCJ, Heo G-J, Oh C, De Zoysa M, Lee J (2018) Chitosan nanoparticles: a positive immune response modulator as display in zebrafish larvae against Aeromonas hydrophila infection. Fish Shellfish Immunol 76:240\u2013246","journal-title":"Fish Shellfish Immunol"},{"key":"12693_CR69","volume-title":"National Academy Press","author":"NRC","year":"2011","unstructured":"NRC (2011) National Research Council, Nutrient Requirements of Fish. Committee on Animal Nutrition. Board on Agriculture. National Research Council. In: National Academy Press. USA, Washington DC."},{"key":"12693_CR70","first-page":"3005","volume":"11","author":"S Obradovi\u0107","year":"2006","unstructured":"Obradovi\u0107 S, Adamovi\u0107 M, Vuka\u0161inovi\u0107 M, Jovanovi\u0107 R, Levic J (2006) The application effects of natural zeolite in feed and water on production results of Oncorhynchus mykiss (Walbaum). Roumanian Biotechnological Letters 11:3005\u20133013","journal-title":"Roumanian Biotechnological Letters"},{"key":"12693_CR71","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/978-1-4614-9590-1_18","volume-title":"Seafood processing by-products","author":"UMSP Perera","year":"2014","unstructured":"Perera UMSP, Rajapakse N (2014) Chitosan nanoparticles: preparation, characterization, and applications. In: Seafood processing by-products. Springer, New York, NY, pp 371\u2013387"},{"key":"12693_CR72","doi-asserted-by":"crossref","first-page":"159","DOI":"10.17221\/2317-CJAS","volume":"52","author":"D Prvulovi\u0107","year":"2007","unstructured":"Prvulovi\u0107 D, Jovanovi\u0107-Galovi\u0107 A, Stani\u0107 B, Popovi\u0107 M, Grubor-Laj\u0161i\u0107 G (2007) Effects of a clinoptilolite supplement in pig diets on performance and serum parameters. Czech J Anim Sci 52:159\u2013166","journal-title":"Czech J Anim Sci"},{"key":"12693_CR73","unstructured":"Ramani M (2001) Lethal and sublethal toxicity of monocrotophos an organophosphate on the juveniles of rohu Labeo rohita (ham.) under tropical conditions, Department of Fishery Biology, College of Fisheries, Panangad"},{"key":"12693_CR74","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","volume":"28","author":"S Reitman","year":"1957","unstructured":"Reitman S, Frankel S (1957) A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 28:56\u201363","journal-title":"Am J Clin Pathol"},{"key":"12693_CR75","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.aquatox.2005.06.003","volume":"74","author":"F S\u00e1nchez-Bayo","year":"2005","unstructured":"S\u00e1nchez-Bayo F, Goka K (2005) Unexpected effects of zinc pyrithione and imidacloprid on Japanese medaka fish (Oryzias latipes). Aquat Toxicol 74:285\u2013293","journal-title":"Aquat Toxicol"},{"key":"12693_CR76","unstructured":"Secombes CJ (1990) Isolation of salmonid macrophages and analysis of their killing activity. Techniques Fish Immunol:137\u2013154"},{"key":"12693_CR77","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0304-3835(00)00551-6","volume":"159","author":"W-G Seo","year":"2000","unstructured":"Seo W-G, Pae H-O, Kim N-Y, Oh G-S, Park I-S, Kim Y-H, Kim Y-M, Lee Y-h, Jun C-D, Chung H-T (2000) Synergistic cooperation between water-soluble chitosan oligomers and interferon-\u03b3 for induction of nitric oxide synthesis and tumoricidal activity in murine peritoneal macrophages. Cancer Lett 159:189\u2013195","journal-title":"Cancer Lett"},{"key":"12693_CR78","doi-asserted-by":"crossref","first-page":"5955","DOI":"10.1111\/are.13418","volume":"48","author":"N Sheikhzadeh","year":"2017","unstructured":"Sheikhzadeh N, Kouchaki M, Mehregan M, Tayefi-Nasrabadi H, Divband B, Khataminan M, Khani Oushani A, Shabanzadeh S (2017) Influence of nanochitosan\/zeolite composite on growth performance, digestive enzymes and serum biochemical parameters in rainbow trout (Oncorhynchus mykiss). Aquac Res 48:5955\u20135964","journal-title":"Aquac Res"},{"key":"12693_CR79","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1577\/1548-8667(1999)011<0183:EOPETT>2.0.CO;2","volume":"11","author":"DA Smith","year":"1999","unstructured":"Smith DA, Smith SA, Holladay SD (1999) Effect of previous exposure to tricaine methanesulfonate on time to anesthesia in hybrid tilapias. J Aquat Anim Health 11:183\u2013186","journal-title":"J Aquat Anim Health"},{"key":"12693_CR80","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.scitotenv.2016.09.167","volume":"575","author":"V Storck","year":"2017","unstructured":"Storck V, Karpouzas DG, Martin-Laurent F (2017) Towards a better pesticide policy for the European Union. Sci Total Environ 575:1027\u20131033","journal-title":"Sci Total Environ"},{"key":"12693_CR81","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1093\/clinchem\/29.5.751","volume":"29","author":"N Tietz","year":"1983","unstructured":"Tietz N, Burtis C, Duncan P, Ervin K, Petitclerc C, Rinker A, Shuey D, Zygowicz E (1983) A reference method for measurement of alkaline phosphatase activity in human serum. Clin Chem 29:751\u2013761","journal-title":"Clin Chem"},{"key":"12693_CR82","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.chemosphere.2009.05.002","volume":"76","author":"T Ti\u0161ler","year":"2009","unstructured":"Ti\u0161ler T, Jemec A, Mozeti\u010d B, Treb\u0161e P (2009) Hazard identification of imidacloprid to aquatic environment. Chemosphere 76:907\u2013914","journal-title":"Chemosphere"},{"key":"12693_CR83","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.pharmtox.45.120403.095930","volume":"45","author":"M Tomizawa","year":"2005","unstructured":"Tomizawa M, Casida JE (2005) Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol 45:247\u2013268","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"12693_CR84","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.chemosphere.2017.02.047","volume":"175","author":"A Topal","year":"2017","unstructured":"Topal A, Alak G, Ozkaraca M, Yeltekin AC, Comakl\u0131 S, Ac\u0131l G, Kokturk M, Atamanalp M (2017) Neurotoxic responses in brain tissues of rainbow trout exposed to imidacloprid pesticide: assessment of 8-hydroxy-2-deoxyguanosine activity, oxidative stress and acetylcholinesterase activity. Chemosphere 175:186\u2013191","journal-title":"Chemosphere"},{"key":"12693_CR85","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0003-2697(78)90342-1","volume":"86","author":"M Uchiyama","year":"1978","unstructured":"Uchiyama M, Mihara M (1978) Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86:271\u2013278","journal-title":"Anal Biochem"},{"key":"12693_CR86","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1016\/S0142-9612(00)00401-4","volume":"22","author":"H Ueno","year":"2001","unstructured":"Ueno H, Nakamura F, Murakami M, Okumura M, Kadosawa T, Fujinaga T (2001) Evaluation effects of chitosan for the extracellular matrix production by fibroblasts and the growth factors production by macrophages. Biomaterials 22:2125\u20132130","journal-title":"Biomaterials"},{"key":"12693_CR87","doi-asserted-by":"crossref","unstructured":"Vieira CED, P\u00e9rez MR, Acayaba RDA, Raimundo CCM, dos Reis Martinez CB (2018): DNA damage and oxidative stress induced by imidacloprid exposure in different tissues of the Neotropical fish Prochilodus lineatus. Chemosphere 195, 125-134","DOI":"10.1016\/j.chemosphere.2017.12.077"},{"key":"12693_CR88","first-page":"1318","volume":"9","author":"TC Villamil La","year":"2002","unstructured":"Villamil La TC, Figueras A, Novoa B (2002) Evaluation of immunomodulatory effects of lactic acid bacteria in turbot (Scophthalmus maximus). Clin Diagn Lab Immunol 9:1318\u20131323","journal-title":"Clin Diagn Lab Immunol"},{"key":"12693_CR89","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3109\/17435390.2010.530354","volume":"5","author":"Y Wang","year":"2011","unstructured":"Wang Y, Li J (2011) Effects of chitosan nanoparticles on survival, growth and meat quality of tilapia, Oreochromis nilotica. Nanotoxicology 5:425\u2013431","journal-title":"Nanotoxicology"},{"key":"12693_CR90","first-page":"32","volume":"51","author":"MM Wintrobe","year":"1934","unstructured":"Wintrobe MM (1934) Variations in the size and hemoglobin content of erythrocytes in the blood of various vertebrates. Folia Haematologica 51:32\u201349","journal-title":"Folia Haematologica"},{"key":"12693_CR91","volume-title":"Microanalysis in medical biochemistry","author":"ID Wotton","year":"1982","unstructured":"Wotton ID, Freeman H (1982) Microanalysis in medical biochemistry. Churchill, New York, USA"},{"key":"12693_CR92","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.fct.2006.07.025","volume":"45","author":"GJ Wu","year":"2007","unstructured":"Wu GJ, Tsai GJ (2007) Chitooligosaccharides in combination with interferon-\u03b3 increase nitric oxide production via nuclear factor-\u03baB activation in murine RAW264.7 macrophages. Food Chem Toxicol 45:250\u2013258","journal-title":"Food Chem Toxicol"},{"key":"12693_CR93","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/S0960-894X(01)00285-2","volume":"11","author":"W Xie","year":"2001","unstructured":"Xie W, Xu P, Liu Q (2001) Antioxidant activity of water-soluble chitosan derivatives. Bioorg Med Chem Lett 11:1699\u20131701","journal-title":"Bioorg Med Chem Lett"},{"key":"12693_CR94","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.carbpol.2008.05.003","volume":"74","author":"M-T Yen","year":"2008","unstructured":"Yen M-T, Yang J-H, Mau J-L (2008) Antioxidant properties of chitosan from crab shells. Carbohydr Polym 74:840\u2013844","journal-title":"Carbohydr Polym"},{"key":"12693_CR95","first-page":"1567","volume":"8","author":"\u00d6 Yildirim","year":"2009","unstructured":"Yildirim \u00d6, T\u00fcrker A, Senel B (2009) Effects of natural zeolite (clinoptilolite) levels in fish diet on water quality, growth performance and nutrient utilization of Tilapia (Tilapia zillii) fry. Fresenius Environ Bull 8:1567\u20131571","journal-title":"Fresenius Environ Bull"},{"key":"12693_CR96","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.734562","volume":"515","author":"E Zahran","year":"2020","unstructured":"Zahran E, Risha E, Hamed M, Ibrahim T, Pali\u0107 D (2020) Dietary mycotoxicosis prevention with modified zeolite (Clinoptilolite) feed additive in Nile tilapia (Oreochromis niloticus). Aquaculture 515:734562","journal-title":"Aquaculture"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-12693-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-021-12693-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-12693-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T09:39:06Z","timestamp":1624441146000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-021-12693-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,9]]},"references-count":95,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["12693"],"URL":"https:\/\/doi.org\/10.1007\/s11356-021-12693-4","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,9]]},"assertion":[{"value":"3 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All techniques and methodologies used during the experimental work are closely followed by the Local Experimental Animal Care Committee ethical and approved by the Institutional Ethics Committee, Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, Egypt. All authors participated equally in this manuscript","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors agree with submission and publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests<b>.<\/b>","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}