{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T16:26:07Z","timestamp":1781108767453,"version":"3.54.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"32","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s11356-021-13806-9","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T03:43:46Z","timestamp":1618285426000},"page":"44420-44431","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Long-term exposure to p-Nitrophenol induces hepatotoxicity via accelerating apoptosis and glycogen accumulation in male Japanese quails"],"prefix":"10.1007","volume":"28","author":[{"given":"Eman A.","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howayda E.","family":"Khaled","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3384-626X","authenticated-orcid":false,"given":"Ahmed K.","family":"Elsayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"13806_CR1","doi-asserted-by":"publisher","first-page":"e72991","DOI":"10.1371\/journal.pone.0072991","volume":"8","author":"MM Abdel-Daim","year":"2013","unstructured":"Abdel-Daim MM, Abuzead SM, Halawa SM (2013) Protective role of Spirulina platensis against acute deltamethrin-induced toxicity in rats. PLoS One 8:e72991","journal-title":"PLoS One"},{"key":"13806_CR2","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/0272-0590(86)90233-2","volume":"6","author":"MB Abou-Donia","year":"1986","unstructured":"Abou-Donia MB, Nomeir AA (1986) The role of pharmacokinetics and metabolism in species sensitivity to neurotoxic agents. Fundam Appl Toxicol 6:190\u2013207","journal-title":"Fundam Appl Toxicol"},{"key":"13806_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1093\/toxsci\/53.1.5","volume":"53","author":"AW Abu-Qare","year":"2000","unstructured":"Abu-Qare AW, Abdel-Rahman AA, Kishk AM, Abou-Donia MB (2000) Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats. Toxicol Sci 53:5\u201312","journal-title":"Toxicol Sci"},{"key":"13806_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0378-4274(01)00409-X","volume":"125","author":"AW Abu-Qare","year":"2001","unstructured":"Abu-Qare AW, Abdel-Rahman AA, Ahmad H, Kishk AM, Abou-Donia MB (2001) Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens. Toxicol Lett 125:1\u201310","journal-title":"Toxicol Lett"},{"key":"13806_CR5","doi-asserted-by":"publisher","first-page":"10930","DOI":"10.1007\/s11356-015-4245-9","volume":"22","author":"E Ahmed","year":"2015","unstructured":"Ahmed E, Nagaoka K, Fayez M, Abdel-Daim MM, Samir H, Watanabe G (2015a) Suppressive effects of long-term exposure to P-nitrophenol on gonadal development, hormonal profile with disruption of tissue integrity, and activation of caspase-3 in male Japanese quail (Coturnix japonica). Environ Sci Pollut Res Int 22:10930\u201310942","journal-title":"Environ Sci Pollut Res Int"},{"key":"13806_CR6","first-page":"115","volume":"63","author":"E Ahmed","year":"2015","unstructured":"Ahmed E, Nagaoka K, Fayez M, Samir H, Watanabe G (2015b) Long-term p-nitrophenol exposure can disturb liver metabolic cytochrome P450 genes together with aryl hydrocarbon receptor in Japanese quail. Jpn J Vet Res 63:115\u2013127","journal-title":"Jpn J Vet Res"},{"key":"13806_CR7","doi-asserted-by":"publisher","first-page":"1294074","DOI":"10.1155\/2020\/1294074","volume":"2020","author":"LA Alenazy","year":"2020","unstructured":"Alenazy LA, Javed M, Elsiesy H, Raddaoui E, Al-Hamoudi WK (2020) Glycogenic hepatopathy: a rare hepatic complication of poorly controlled type 1 DM. Case Rep Med 2020:1294074","journal-title":"Case Rep Med"},{"key":"13806_CR8","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1093\/ilar.51.4.310","volume":"51","author":"GF Ball","year":"2010","unstructured":"Ball GF, Balthazart J (2010) Japanese quail as a model system for studying the neuroendocrine control of reproductive and social behaviors. ILAR J 51:310\u2013325","journal-title":"ILAR J"},{"key":"13806_CR9","unstructured":"Bancroft JD, Gamble M (2008) Theory and practice of histological techniques. Elsevier health sciences"},{"key":"13806_CR10","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.snb.2007.11.022","volume":"131","author":"RM Banik","year":"2008","unstructured":"Banik RM, Mayank, Prakash R, Upadhyay SN (2008) Microbial biosensor based on whole cell of Pseudomonas sp. for online measurement of p-Nitrophenol. Sensors Actuators B Chem 131:295\u2013300","journal-title":"Sensors Actuators B Chem"},{"key":"13806_CR11","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/BF01055545","volume":"9","author":"DJ Call","year":"1980","unstructured":"Call DJ, Brooke LT, Lu PY (1980) Uptake, elimination, and metabolism of three phenols by fathead minnows. Arch Environ Contam Toxicol 9:699\u2013714","journal-title":"Arch Environ Contam Toxicol"},{"key":"13806_CR12","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.etap.2015.12.011","volume":"41","author":"J Chen","year":"2016","unstructured":"Chen J, Song M, Li Y, Zhang Y, Taya K, Li C (2016) The effect of phytosterol protects rats against 4-nitrophenol-induced liver damage. Environ Toxicol Pharmacol 41:266\u2013271","journal-title":"Environ Toxicol Pharmacol"},{"key":"13806_CR13","unstructured":"Crosby K, Simendinger J, Grange C, Ferrante M, Bernier T, Standen C (2014) Immunohistochemistry protocol for paraffin\u2010embedded tissue sections advertisement. Cell Signal Technol 86:e50641\u2013e50646. Retrieved from https:\/\/www.jove.com\/t\/5064\/immunohistochemistry-protocol-for-paraffin-embedded-tissue-sections"},{"key":"13806_CR14","unstructured":"David HV, Zafar I (1990): Aminotransferases. In: rd, Walker HK, Hall WD, Hurst JW (eds) Clinical methods: the history, physical, and laboratory examinations. Boston"},{"key":"13806_CR15","doi-asserted-by":"publisher","first-page":"e16","DOI":"10.1309\/LMBR83WM3GNJEDLS","volume":"45","author":"M Esani","year":"2014","unstructured":"Esani M (2014) The physiological sources of, clinical significance of, and laboratory-testing methods for determining enzyme levels. Lab Med 45:e16\u2013e18","journal-title":"Lab Med"},{"key":"13806_CR16","doi-asserted-by":"publisher","first-page":"151463","DOI":"10.1016\/j.acthis.2019.151463","volume":"122","author":"AK Grzegorzewska","year":"2020","unstructured":"Grzegorzewska AK, Hrabia A, Kowalik K, Katarzynska-Banasik D, Kozubek A, Sechman A (2020) In vitro effects of PNP and PNMC on apoptosis and proliferation in the hen ovarian stroma and prehierarchal follicles. Acta Histochem 122:151463","journal-title":"Acta Histochem"},{"key":"13806_CR17","doi-asserted-by":"crossref","unstructured":"Hansen WM, D GJ, Sandra MC (2011) Enzymatic activity in turkey, duck, quail and chicken liver microsomes against four human cytochrome P450 prototypesubstrates and aflatoxin B. Xenobiotics 1.IPCS, I.P.o.C.S.Organophosphate Pesticides","DOI":"10.4081\/xeno.2011.e4"},{"key":"13806_CR18","doi-asserted-by":"publisher","first-page":"756","DOI":"10.3390\/s6070756","volume":"6","author":"X-J Huang","year":"2006","unstructured":"Huang X-J, Choi Y-K, Im H-S, Yarimaga O, Yoon E, Kim H-S (2006) Aspartate aminotransferase (AST\/GOT) and alanine aminotransferase (ALT\/GPT) detection techniques. Sensors 6:756\u2013782","journal-title":"Sensors"},{"key":"13806_CR19","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/carcin\/18.1.185","volume":"18","author":"T Ichinose","year":"1997","unstructured":"Ichinose T, Yajima Y, Nagashima M, Takenoshita S, Nagamachi Y, Sagai M (1997) Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles. Carcinogenesis 18:185\u2013192","journal-title":"Carcinogenesis"},{"key":"13806_CR20","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/j.cgh.2007.02.036","volume":"5","author":"MI Kafrouni","year":"2007","unstructured":"Kafrouni MI, Anders RA, Verma S (2007) Hepatotoxicity associated with dietary supplements containing anabolic steroids. Clin Gastroenterol Hepatol 5:809\u2013812","journal-title":"Clin Gastroenterol Hepatol"},{"key":"13806_CR21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.envpol.2016.01.055","volume":"212","author":"A Karami","year":"2016","unstructured":"Karami A, Romano N, Hamzah H, Simpson SL, Yap CK (2016) Acute phenanthrene toxicity to juvenile diploid and triploid African catfish (Clarias gariepinus): molecular, biochemical, and histopathological alterations. Environ Pollut 212:155\u2013165","journal-title":"Environ Pollut"},{"key":"13806_CR22","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1111\/j.1600-0676.1992.tb00571.x","volume":"12","author":"K Kayano","year":"1992","unstructured":"Kayano K, Yasunaga M, Kubota M, Takenaka K, Mori K, Yamashita A, Kubo Y, Sakaida I, Okita K, Sanuki K (1992) Detection of proliferating hepatocytes by immunohistochemical staining for proliferating cell nuclear antigen (PCNA) in patients with acute hepatic failure. Liver 12:132\u2013136","journal-title":"Liver"},{"key":"13806_CR23","doi-asserted-by":"publisher","first-page":"108638","DOI":"10.1016\/j.cbpc.2019.108638","volume":"228","author":"S Kuang","year":"2020","unstructured":"Kuang S, Le Q, Hu J, Wang Y, Yu N, Cao X, Zhang M, Sun Y, Gu W, Yang Y (2020a) Effects of p-nitrophenol on enzyme activity, histology, and gene expression in Larimichthys crocea. Comp Biochem Physiol C Toxicol Pharmacol 228:108638","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"13806_CR24","doi-asserted-by":"publisher","first-page":"108638","DOI":"10.1016\/j.cbpc.2019.108638","volume":"228","author":"S Kuang","year":"2020","unstructured":"Kuang S, Le Q, Hu J, Wang Y, Yu N, Cao X, Zhang M, Sun Y, Gu W, Yang Y, Zhang Y, Li Y, Liu H, Yan X (2020b) Effects of p-nitrophenol on enzyme activity, histology, and gene expression in Larimichthys crocea. Comp Biochem Physiol C Toxicol Pharmacol 228:108638","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"13806_CR25","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1093\/aje\/kws469","volume":"178","author":"S Kunutsor","year":"2013","unstructured":"Kunutsor S, Apekey T, Walley J (2013) Liver aminotransferases and risk of incident type 2 diabetes: a systematic review and meta-analysis. Am J Epidemiol 178:159\u2013171","journal-title":"Am J Epidemiol"},{"key":"13806_CR26","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1097\/00007691-200202000-00022","volume":"24","author":"TC Kwong","year":"2002","unstructured":"Kwong TC (2002) Organophosphate pesticides: biochemistry and clinical toxicology. Ther Drug Monit 24:144\u2013149","journal-title":"Ther Drug Monit"},{"key":"13806_CR27","doi-asserted-by":"publisher","first-page":"4778","DOI":"10.1016\/j.bbagen.2013.06.008","volume":"1830","author":"SH Lam","year":"2013","unstructured":"Lam SH, Ung CY, Hlaing MM, Hu J, Li ZH, Mathavan S, Gong Z (2013) Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses. Biochim Biophys Acta 1830:4778\u20134789","journal-title":"Biochim Biophys Acta"},{"key":"13806_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.taap.2006.06.010","volume":"217","author":"C Li","year":"2006","unstructured":"Li C, Taneda S, Suzuki AK, Furuta C, Watanabe G, Taya K (2006) Estrogenic and anti-androgenic activities of 4-nitrophenol in diesel exhaust particles. Toxicol Appl Pharmacol 217:1\u20136","journal-title":"Toxicol Appl Pharmacol"},{"key":"13806_CR29","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1007\/s12020-009-9192-0","volume":"36","author":"X Li","year":"2009","unstructured":"Li X, Li C, Suzuki AK, Taneda S, Watanabe G, Taya K (2009) 4-Nitrophenol isolated from diesel exhaust particles disrupts regulation of reproductive hormones in immature male rats. Endocrine 36:98\u2013102","journal-title":"Endocrine"},{"key":"13806_CR30","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s12576-011-0183-6","volume":"62","author":"SQ Li","year":"2012","unstructured":"Li SQ, Li RF, Xi SM, Hu S, Jia ZQ, Li SP, Wen XL, Song YK, Li S, Li SP, Wei FB, Chen XL (2012) Systematical analysis of impacts of heat stress on the proliferation, apoptosis and metabolism of mouse hepatocyte. J Physiol Sci 62:29\u201343","journal-title":"J Physiol Sci"},{"key":"13806_CR31","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1093\/toxsci\/68.2.508","volume":"68","author":"MK Lingohr","year":"2002","unstructured":"Lingohr MK, Bull RJ, Kato-Weinstein J, Thrall BD (2002) Dichloroacetate stimulates glycogen accumulation in primary hepatocytes through an insulin-independent mechanism. Toxicol Sci 68:508\u2013515","journal-title":"Toxicol Sci"},{"key":"13806_CR32","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.acthis.2013.02.012","volume":"115","author":"JW Lu","year":"2013","unstructured":"Lu JW, Yang WY, Lin YM, Jin SL, Yuh CH (2013) Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta Histochem 115:728\u2013739","journal-title":"Acta Histochem"},{"key":"13806_CR33","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/0006-2952(82)90464-6","volume":"31","author":"M Machida","year":"1982","unstructured":"Machida M, Morita Y, Hayashi M, Awazu S (1982) Pharmacokinetic evidence for the occurrence of extrahepatic conjugative metabolism of p-nitrophenol in rats. Biochem Pharmacol 31:787\u2013791","journal-title":"Biochem Pharmacol"},{"key":"13806_CR34","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3844\/ajavsp.2010.20.26","volume":"5","author":"E Maroufyan","year":"2010","unstructured":"Maroufyan E, Kasim A, Hashemi SR, Loh TC, Bejo MH (2010) Change in growth performance and liver function enzymes of broiler chickens challenged with infectious bursal disease virus to dietary supplementation of methionine and threonine. Am J Anim Vet Sci 5:20\u201326","journal-title":"Am J Anim Vet Sci"},{"key":"13806_CR35","first-page":"851","volume":"6","author":"T Mizuma","year":"1983","unstructured":"Mizuma T, Hayashi M, Awazu S (1983) p-Nitrophenol sulfation in rat liver cytosol: multiple forms and substrate inhibition of aryl sulfotransferase. Aust J Pharm 6:851\u2013858","journal-title":"Aust J Pharm"},{"key":"13806_CR36","unstructured":"Moregaonkar S, Somkuwar A, Pathan M (2011): quail laboratory model for toxicological studies, National seminar on Toxicopathology, IAVP, West Zone, BVC, Mumbai"},{"key":"13806_CR37","unstructured":"OECD (1993): (Organization for Economic Cooperation and Development): OECD guidelines for the testing of chemicals. Section2 \u2013 Effect on Biotic Systems: Test Guideline 206: Avian Reproduction Test. Paris, France: OCD"},{"key":"13806_CR38","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.ygcen.2009.05.007","volume":"163","author":"MA Ottinger","year":"2009","unstructured":"Ottinger MA, Lavoie ET, Thompson N, Bohannon M, Dean K, Quinn MJ Jr (2009) Is the gonadotropin releasing hormone system vulnerable to endocrine disruption in birds? Gen Comp Endocrinol 163:104\u2013108","journal-title":"Gen Comp Endocrinol"},{"key":"13806_CR39","volume-title":"Toxicological profile for nitrophenols","author":"Registry AAfTSaD","year":"1992","unstructured":"Registry AAfTSaD (1992) Toxicological profile for nitrophenols. Public Health Service, U.S. Department of Health and Human Services, Atlanta"},{"key":"13806_CR40","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3109\/10408368409167137","volume":"21","author":"R Rej","year":"1984","unstructured":"Rej R, Shaw LM (1984) Measurement of aminotransferases: Part 1. Aspartate aminotransferase. CRC Crit Rev Clin Lab Sci 21:99\u2013186","journal-title":"CRC Crit Rev Clin Lab Sci"},{"key":"13806_CR41","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0891-5849(93)90507-Q","volume":"14","author":"M Sagai","year":"1993","unstructured":"Sagai M, Saito H, Ichinose T, Kodama M, Mori Y (1993) Biological effects of diesel exhaust particles. I. In vitro production of superoxide and in vivo toxicity in mouse. Free Radic Biol Med 14:37\u201347","journal-title":"Free Radic Biol Med"},{"key":"13806_CR42","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1262\/jrd.19112","volume":"54","author":"M Sedqyar","year":"2008","unstructured":"Sedqyar M, Weng Q, Watanabe G, Kandiel MM, Takahashi S, Suzuki AK, Taneda S, Taya K (2008) Secretion of inhibin in female Japanese quails (Coturnix japonica) from hatch to sexual maturity. J Reprod Dev 54:52\u201357","journal-title":"J Reprod Dev"},{"key":"13806_CR43","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1079\/WPS19840022","volume":"40","author":"K Shim","year":"1984","unstructured":"Shim K, Vohra P (1984) A review of the nutrition of Japanese quail. World\u2019s Poultry Sci J 40:261\u2013274","journal-title":"World\u2019s Poultry Sci J"},{"key":"13806_CR44","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s11259-006-2503-5","volume":"30","author":"S Sodhi","year":"2006","unstructured":"Sodhi S, Sharma A, Brar RS (2006) A protective effect of vitamin E and selenium in ameliorating the immunotoxicity of malathion in chicks. Vet Res Commun 30:935\u2013942","journal-title":"Vet Res Commun"},{"key":"13806_CR45","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1248\/bpb.27.835","volume":"27","author":"S Taneda","year":"2004","unstructured":"Taneda S, Mori Y, Kamata K, Hayashi H, Furuta C, Li C, Seki K, Sakushima A, Yoshino S, Yamaki K, Watanabe G, Taya K, Suzuki AK (2004) Estrogenic and anti-androgenic activity of nitrophenols in diesel exhaust particles (DEP). Biol Pharm Bull 27:835\u2013837","journal-title":"Biol Pharm Bull"},{"key":"13806_CR46","doi-asserted-by":"crossref","unstructured":"Timbrell JA (2020) The liver as a target organ for toxicity. Target Organ Toxicity, Volume I, 1","DOI":"10.4324\/9780429290299-1"},{"key":"13806_CR47","volume-title":"Health effects assessment for nitrophenols","author":"US EPA","year":"1987","unstructured":"US EPA (1987) Health effects assessment for nitrophenols. United States Environmental Protection Agency, Washington"},{"key":"13806_CR48","unstructured":"US-EPA (1996): US Environmental Protection Agency, Avian Reproduction Test: OPPTS 850\u00b72300 \u2018Public Draft\u2019 Ecological Effects Test Guidelines. EPA 712-C-96\u2013141. United States Environmental Protection Agency, Washington"},{"key":"13806_CR49","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.pestbp.2006.06.010","volume":"87","author":"M Uzunhisarcikli","year":"2007","unstructured":"Uzunhisarcikli M, Kalender Y, Dirican K, Kalender S, Ogutcu A, Buyukkomurcu F (2007) Acute, subacute and subchronic administration of methyl parathion-induced testicular damage in male rats and protective role of vitamins C and E. Pestic Biochem Physiol 87:115\u2013122","journal-title":"Pestic Biochem Physiol"},{"key":"13806_CR50","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/S1734-1140(13)71073-9","volume":"65","author":"E Wisniewska","year":"2013","unstructured":"Wisniewska E, Dylik A, Kulza M, Florek E, Piekoszewski W, Senczuk-Przybylowska M, Marszalek A (2013) Exposure to ethanol and tobacco smoke in relation to level of PCNA antigen expression in pancreatic and hepatic rat cells. Pharmacol Rep 65:914\u2013926","journal-title":"Pharmacol Rep"},{"key":"13806_CR51","unstructured":"WWAP (2019) UNESCO World Water Assessment Programme: The United Nations World Water Development Report 2019: Leaving No One Behind; UNESCO: Paris, France."},{"key":"13806_CR52","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.rvsc.2010.12.009","volume":"91","author":"Z Yue","year":"2011","unstructured":"Yue Z, She R, Bao H, Li W, Wang D, Zhu J, Chang L, Yu P (2011) Exposure to 3-methyl-4-nitrophenol affects testicular morphology and induces spermatogenic cell apoptosis in immature male rats. Res Vet Sci 91:261\u2013268","journal-title":"Res Vet Sci"},{"key":"13806_CR53","doi-asserted-by":"publisher","first-page":"111809","DOI":"10.1016\/j.yexcr.2019.111809","volume":"388","author":"F Zhan","year":"2020","unstructured":"Zhan F, Zhong Y, Qin Y, Li L, Wu W, Yao M (2020) SND1 facilitates the invasion and migration of cervical cancer cells by Smurf1-mediated degradation of FOXA2. Exp Cell Res 388:111809","journal-title":"Exp Cell Res"},{"key":"13806_CR54","doi-asserted-by":"publisher","first-page":"6384","DOI":"10.1021\/es1011093","volume":"44","author":"G Zhang","year":"2010","unstructured":"Zhang G, Gao Y, Zhang Y, Guo Y (2010) Fe2O3-pillared rectorite as an efficient and stable Fenton-like heterogeneous catalyst for photodegradation of organic contaminants. Environ Sci Technol 44:6384\u20136389","journal-title":"Environ Sci Technol"},{"key":"13806_CR55","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.toxlet.2013.09.011","volume":"223","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Piao Y, Li Y, Song M, Tang P, Li C (2013) 4-Nitrophenol induces Leydig cells hyperplasia, which may contribute to the differential modulation of the androgen receptor and estrogen receptor-alpha and -beta expression in male rat testes. Toxicol Lett 223:228\u2013235","journal-title":"Toxicol Lett"},{"key":"13806_CR56","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.toxrep.2015.04.007","volume":"2","author":"Y Zhang","year":"2015","unstructured":"Zhang Y, Song M, Rui X, Pu S, Li Y, Li C (2015) Supplemental dietary phytosterin protects against 4-nitrophenol-induced oxidative stress and apoptosis in rat testes. Toxicol Rep 2:664\u2013676","journal-title":"Toxicol Rep"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-13806-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-021-13806-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-13806-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T04:03:37Z","timestamp":1671854617000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-021-13806-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,13]]},"references-count":56,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["13806"],"URL":"https:\/\/doi.org\/10.1007\/s11356-021-13806-9","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,13]]},"assertion":[{"value":"4 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"These birds were treated humanely following the established guidelines and principles of Faculty of Veterinary medicine, Suez Canal University, Egypt, which are approved by the ethics committee for using laboratory animals\u2019 experiments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}