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The nearby way is the Wet op de dierproeven (article 9) of Dutch law (international) and an associated rule planned via the Bureau of Animal Research Licensing, Local University, as detailed in our earlier papers (Ali et al. (Ali et al.\n                      \n                      ), (Ali\n                      \n                      ), (Ali et al.\n                      \n                      ); Hussain et al. (Hussain et al.\n                      \n                      ); Ali et al. (Ali et al.\n                      \n                      ), (Ali\n                      \n                      ), (Ali et al.\n                      \n                      ); Ara et al. (Ara et al.\n                      \n                      ); Ali et al. (Ali et al.\n                      \n                      ), (Ali\n                      \n                      ), (Ali et al.\n                      \n                      ); Khan et al. (Khan et al.\n                      \n                      ); Ali et al. (Ali et al.\n                      \n                      ); Mumtaz et al. (Mumtaz et al.\n                      \n                      ); Mughal et al. (Mughal et al.\n                      \n                      ); Dar et al. (Dar et al.\n                      \n                      )). The rearing and use of mice were carried out using NIH Publication \u201cGuide for the Care and Use of Laboratory Animals\u201d (NRC 2004) and with the approval vide No. D\/681\/UZ dated 04-04-2019 by the local bioethical committee of the University on animal experimentation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The rearing and use of mice was following NIH Publication \u201cGuide for the Care and Use of Laboratory Animals\u201d (NRC 2004) and with the approval by the local ethical committee of University of the Punjab, Lahore, Pakistan, on animal experimentation <b>(<\/b>can provide a certificate on demand).*Statement about this also added in manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}