{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:52:50Z","timestamp":1793130770881,"version":"4.5.0"},"reference-count":145,"publisher":"Springer Science and Business Media LLC","issue":"22","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1007\/s11356-021-17090-5","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T03:02:31Z","timestamp":1644548551000},"page":"32383-32396","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies"],"prefix":"10.1007","volume":"29","author":[{"given":"Ali","family":"Asghari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Nourmohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamidreza","family":"Majidiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyyed Ali","family":"Shariatzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davood","family":"Anvari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadegh","family":"Shamsinia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezatollah","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7124-4908","authenticated-orcid":false,"given":"Morteza","family":"Shams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholam","family":"Basati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"17090_CR1","doi-asserted-by":"publisher","first-page":"3996","DOI":"10.1073\/pnas.0609028104","volume":"104","author":"I Airoldi","year":"2007","unstructured":"Airoldi I et al (2007) Endogenous IL-12 triggers an antiangiogenic program in melanoma cells. Proc Natl Acad Sci 104:3996\u20134001","journal-title":"Proc Natl Acad Sci"},{"key":"17090_CR2","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.1002\/cncr.11752","volume":"98","author":"H Akg\u00fcl","year":"2003","unstructured":"Akg\u00fcl H, Tez M, \u00dcnal AE, Ke\u015fkek M, Sayek \u0130, \u00d6z\u00e7elik T (2003) Echinococcus against cancer: why not? Cancer 98:1998\u20131999","journal-title":"Cancer"},{"key":"17090_CR3","doi-asserted-by":"crossref","unstructured":"Almeria S, Dubey J (2020) Foodborne transmission of Toxoplasma gondii infection in the last decade. An overview Research in Veterinary Science","DOI":"10.1016\/j.rvsc.2020.10.019"},{"key":"17090_CR4","doi-asserted-by":"publisher","first-page":"151863","DOI":"10.1016\/j.imbio.2019.10.012","volume":"225","author":"JP \u00c1lvarez","year":"2020","unstructured":"\u00c1lvarez JP et al (2020) Structural bases that underline Trypanosoma cruzi calreticulin proinfective, antiangiogenic and antitumor properties. Immunobiology 225:151863","journal-title":"Immunobiology"},{"key":"17090_CR5","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1158\/2159-8290.CD-17-0343","volume":"7","author":"N Amirouchene-Angelozzi","year":"2017","unstructured":"Amirouchene-Angelozzi N, Swanton C, Bardelli A (2017) Tumor evolution as a therapeutic target. Cancer Discov 7:805\u2013817","journal-title":"Cancer Discov"},{"key":"17090_CR6","doi-asserted-by":"publisher","first-page":"6258","DOI":"10.1158\/1078-0432.CCR-14-1457","volume":"20","author":"SJ Antonia","year":"2014","unstructured":"Antonia SJ, Larkin J, Ascierto PA (2014) Immuno-oncology combinations: a review of clinical experience and future prospects. Clin Cancer Res 20:6258\u20136268","journal-title":"Clin Cancer Res"},{"key":"17090_CR7","doi-asserted-by":"publisher","first-page":"469","DOI":"10.4049\/jimmunol.1201209","volume":"190","author":"JR Baird","year":"2013","unstructured":"Baird JR et al (2013a) Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge. J Immunol 190:469\u2013478","journal-title":"J Immunol"},{"key":"17090_CR8","doi-asserted-by":"publisher","first-page":"3842","DOI":"10.1158\/0008-5472.CAN-12-1974","volume":"73","author":"JR Baird","year":"2013","unstructured":"Baird JR et al (2013b) Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Res 73:3842\u20133851","journal-title":"Cancer Res"},{"key":"17090_CR9","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1007\/s10517-006-0395-6","volume":"142","author":"Z Batmonkh","year":"2006","unstructured":"Batmonkh Z, Kallinikova V, Pakhorukova L, Kravtsov E, Karpenko L, Dalin M (2006) In vivo anticancer activity of lysates from Trypanosoma cruzi of different genetic groups. Bull Exp Biol Med 142:470\u2013473","journal-title":"Bull Exp Biol Med"},{"key":"17090_CR10","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1093\/carcin\/bgp022","volume":"30","author":"F Bazile","year":"2009","unstructured":"Bazile F, Pascal A, Arnal I, Le Clainche C, Chesnel F, Kubiak JZ (2009) Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells. Carcinogenesis 30:555\u2013565","journal-title":"Carcinogenesis"},{"key":"17090_CR11","doi-asserted-by":"crossref","unstructured":"Berriel E et al. (2013) Antitumor activity of human hydatid cyst fluid in a murine model of colon cancer. Scientific World J 2013","DOI":"10.1155\/2013\/230176"},{"key":"17090_CR12","doi-asserted-by":"publisher","first-page":"2402","DOI":"10.1038\/sj.emboj.7600247","volume":"23","author":"KP Bhat","year":"2004","unstructured":"Bhat KP, Itahana K, Jin A, Zhang Y (2004) Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. EMBO J 23:2402\u20132412","journal-title":"EMBO J"},{"key":"17090_CR13","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1038\/ni.1937","volume":"11","author":"SK Biswas","year":"2010","unstructured":"Biswas SK, Mantovani A (2010) Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nature Immunol 11:889\u2013896","journal-title":"Nature Immunol"},{"key":"17090_CR14","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1017\/S0031182005008036","volume":"131","author":"T Boonmars","year":"2005","unstructured":"Boonmars T, Wu Z, Nagano I, Takahashi Y (2005) What is the role of p53 during the cyst formation of Trichinella spiralis? A comparable study between knockout mice and wild type mice. Parasitology 131:705","journal-title":"Parasitology"},{"key":"17090_CR15","first-page":"394","volume":"68","author":"F Bray","year":"2018","unstructured":"Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries J. CA: A Cancer J Clin 68:394\u2013424","journal-title":"CA: A Cancer J Clin"},{"key":"17090_CR16","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0166-6851(00)00302-9","volume":"111","author":"S Brisse","year":"2000","unstructured":"Brisse S, Dujardin J-C, Tibayrenc M (2000) Identification of six Trypanosoma cruzi lineages by sequence-characterised amplified region markers. Mol Biochem Parasitol 111:95\u2013105","journal-title":"Mol Biochem Parasitol"},{"key":"17090_CR17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1645\/0022-3395(2003)089[0057:COCOAE]2.0.CO;2","volume":"89","author":"C Casaravilla","year":"2003","unstructured":"Casaravilla C, Malgor R, Carmona C (2003) Characterization of carbohydrates of adult Echinococcus granulosus by lectin-binding analysis. J Parasitol 89:57\u201361","journal-title":"J Parasitol"},{"key":"17090_CR18","first-page":"129","volume":"37","author":"JD Choo","year":"2005","unstructured":"Choo JD, Lee JS, Kang JS, Lee HS, Yeom JY, Lee YH (2005) Inhibitory effects of Toxoplasma antigen on proliferation and invasion of human glioma cells. J Korean Neurosurg Soc 37:129\u2013136","journal-title":"J Korean Neurosurg Soc"},{"key":"17090_CR19","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1038\/nm1097","volume":"10","author":"JR Conejo-Garcia","year":"2004","unstructured":"Conejo-Garcia JR et al (2004) Tumor-infiltrating dendritic cell precursors recruited by a \u03b2-defensin contribute to vasculogenesis under the influence of Vegf-A. Nature Med 10:950\u2013958","journal-title":"Nature Med"},{"key":"17090_CR20","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1182\/blood-2004-05-1906","volume":"105","author":"JR Conejo-Garcia","year":"2005","unstructured":"Conejo-Garcia JR, Buckanovich RJ, Benencia F, Courreges MC, Rubin SC, Carroll RG, Coukos G (2005) Vascular leukocytes contribute to tumor vascularization. Blood 105:679\u2013681","journal-title":"Blood"},{"key":"17090_CR21","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1365-2567.2008.03009.x","volume":"126","author":"AJI Cooke","year":"2009","unstructured":"Cooke AJI (2009) Review series on helminths, immune modulation and the hygiene hypothesis: how might infection modulate the onset of type 1 diabetes? J Immunology 126:12\u201317","journal-title":"J Immunology"},{"key":"17090_CR22","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1038\/sj.bjc.6602476","volume":"92","author":"G Coukos","year":"2005","unstructured":"Coukos G, Benencia F, Buckanovich R, Conejo-Garcia J (2005) The role of dendritic cell precursors in tumour vasculogenesis. British J Cancer 92:1182\u20131187","journal-title":"British J Cancer"},{"key":"17090_CR23","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1128\/CMR.15.4.595-612.2002","volume":"15","author":"F Cox","year":"2002","unstructured":"Cox F (2002) History of human parasitology. Clin Microbiol Rev 15:595\u2013612","journal-title":"Clin Microbiol Rev"},{"key":"17090_CR24","doi-asserted-by":"publisher","unstructured":"Crompton DWT (2001) Ascaris and ascariasis. In: Advances in Parasitology, vol 48. Academic Press, pp 285-375. https:\/\/doi.org\/10.1016\/S0065-308X(01)48008-0","DOI":"10.1016\/S0065-308X(01)48008-0"},{"key":"17090_CR25","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1084\/jem.20021910","volume":"197","author":"JM Curtsinger","year":"2003","unstructured":"Curtsinger JM, Lins DC, Mescher MF (2003) Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function. J Exp Med 197:1141\u20131151","journal-title":"J Exp Med"},{"key":"17090_CR26","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1007\/s00436-009-1526-6","volume":"105","author":"RC da Silva","year":"2009","unstructured":"da Silva RC, Langoni HP (2009) Toxoplasma gondii: host\u2013parasite interaction and behavior manipulation. Parasitol Res 105:893\u2013898","journal-title":"Parasitol Res"},{"key":"17090_CR27","doi-asserted-by":"crossref","unstructured":"Daneshpour S, Bahadoran M, Hejazi SH, Eskandarian AA, Mahmoudzadeh M, Darani HY (2016) Common antigens between hydatid cyst and cancers. Advanced Biomed Res 5","DOI":"10.4103\/2277-9175.175242"},{"key":"17090_CR28","doi-asserted-by":"publisher","first-page":"27","DOI":"10.4103\/abr.abr_220_18","volume":"8","author":"S Daneshpour","year":"2019","unstructured":"Daneshpour S, Kefayat AH, Mofid MR, Rad SR, Darani HY (2019a) Effect of hydatid cyst fluid antigens on induction of apoptosis on breast cancer cells. Advanced Biomed Res 8:27","journal-title":"Advanced Biomed Res"},{"key":"17090_CR29","doi-asserted-by":"publisher","unstructured":"Daneshpour S, Rostamirad S, Kefayat A, Mofid M, Safavi A, Darani H (2019b) Identifying the most effective hydatid cyst fluid fraction for anticancer vaccination of 4T1 breast tumor-bearing mice. Int J Prevent Med 10 https:\/\/doi.org\/10.4103\/ijpvm.IJPVM_508_18","DOI":"10.4103\/ijpvm.IJPVM_508_18"},{"key":"17090_CR30","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.2217\/fon.12.155","volume":"8","author":"HY Darani","year":"2012","unstructured":"Darani HY, Yousefi M (2012) Parasites and cancers: parasite antigens as possible targets for cancer immunotherapy. Future Oncol 8:1529\u20131535","journal-title":"Future Oncol"},{"key":"17090_CR31","doi-asserted-by":"publisher","first-page":"653","DOI":"10.4269\/ajtmh.17-0657","volume":"98","author":"ABB De Oliveira","year":"2018","unstructured":"De Oliveira ABB, Alevi KCC, Imperador CHL, Madeira FF, de Azeredo-Oliveira MTV (2018) Parasite\u2013vector interaction of Chagas disease: a mini-review. Am J Tropical Med Hygiene 98:653\u2013655","journal-title":"Am J Tropical Med Hygiene"},{"key":"17090_CR32","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.vetpar.2013.01.050","volume":"194","author":"B Deng","year":"2013","unstructured":"Deng B et al (2013) Identification of the differentially expressed genes in SP2\/0 myeloma cells from Balb\/c mice infected with Trichinella spiralis. Veterinary Parasitol 194:179\u2013182","journal-title":"Veterinary Parasitol"},{"key":"17090_CR33","first-page":"978","volume":"9","author":"XF Deng","year":"2016","unstructured":"Deng XF et al (2016) Antitumor effect of intravenous immunization with malaria genetically attenuated sporozoites through induction of innate and adaptive immunity. Int J Clin Exp Pathol 9:978\u2013986","journal-title":"Int J Clin Exp Pathol"},{"key":"17090_CR34","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1001\/jamaoncol.2019.5367","volume":"6","author":"J Duan","year":"2020","unstructured":"Duan J et al (2020) Use of immunotherapy with programmed cell death 1 vs programmed cell death ligand 1 inhibitors in patients with cancer: a systematic review and meta-analysis. JAMA Oncol 6:375\u2013384","journal-title":"JAMA Oncol"},{"key":"17090_CR35","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1586\/eci.09.39","volume":"5","author":"LJ Edwards","year":"2009","unstructured":"Edwards LJ, Constantinescu CSJEroci (2009) Parasite immunomodulation in autoimmune disease: focus on multiple sclerosis. Expert Rev Clin Immunol 5:487\u2013489","journal-title":"Expert Rev Clin Immunol"},{"key":"17090_CR36","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1006\/expr.2001.4620","volume":"98","author":"DA Errico","year":"2001","unstructured":"Errico DA et al (2001) O-glycosylation in Echinococcus granulosus: identification and characterization of the carcinoma-associated Tn antigen. Experimental Parasitol 98:100\u2013109","journal-title":"Experimental Parasitol"},{"key":"17090_CR37","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/j.molimm.2003.11.018","volume":"40","author":"V Ferreira","year":"2004","unstructured":"Ferreira V et al (2004a) Role of calreticulin from parasites in its interaction with vertebrate hosts. Mol Immunol 40:1279\u20131291","journal-title":"Mol Immunol"},{"key":"17090_CR38","doi-asserted-by":"publisher","first-page":"3042","DOI":"10.4049\/jimmunol.172.5.3042","volume":"172","author":"V Ferreira","year":"2004","unstructured":"Ferreira V et al (2004b) The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi. J Immunol 172:3042\u20133050","journal-title":"J Immunol"},{"key":"17090_CR39","doi-asserted-by":"publisher","first-page":"e90203","DOI":"10.1371\/journal.pone.0090203","volume":"9","author":"J Flegr","year":"2014","unstructured":"Flegr J, Prandota J, Sovi\u010dkov\u00e1 M, Israili ZH (2014) Toxoplasmosis\u2013a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries. PloS one 9:e90203","journal-title":"PloS one"},{"key":"17090_CR40","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1186\/1471-2334-11-274","volume":"11","author":"J Flegr","year":"2011","unstructured":"Flegr J, St\u0159\u00ed\u017e I (2011) Potential immunomodulatory effects of latent toxoplasmosis in humans. BMC Infect Diseases 11:274","journal-title":"BMC Infect Diseases"},{"key":"17090_CR41","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1038\/415926a","volume":"415","author":"BA Fox","year":"2002","unstructured":"Fox BA, Bzik DJ (2002) De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii. Nature 415:926\u2013929","journal-title":"Nature"},{"key":"17090_CR42","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.pt.2013.07.001","volume":"29","author":"BA Fox","year":"2013","unstructured":"Fox BA, Sanders KL, Chen S, Bzik DJ (2013) Targeting tumors with nonreplicating Toxoplasma gondii uracil auxotroph vaccines. Trends Parasitol 29:431\u2013437","journal-title":"Trends Parasitol"},{"key":"17090_CR43","doi-asserted-by":"publisher","first-page":"e1006189","DOI":"10.1371\/journal.pgen.1006189","volume":"12","author":"BA Fox","year":"2016","unstructured":"Fox BA, Sanders KL, Rommereim LM, Guevara RB, Bzik DJ (2016) Secretion of rhoptry and dense granule effector proteins by nonreplicating Toxoplasma gondii uracil auxotrophs controls the development of antitumor immunity. PLoS Genet 12:e1006189","journal-title":"PLoS Genet"},{"key":"17090_CR44","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.4049\/jimmunol.182.2.1069","volume":"182","author":"JP Gigley","year":"2009","unstructured":"Gigley JP, Fox BA, Bzik DJ (2009) Cell-mediated immunity to Toxoplasma gondii develops primarily by local Th1 host immune responses in the absence of parasite replication. J Immunol 182:1069\u20131078","journal-title":"J Immunol"},{"key":"17090_CR45","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s10555-008-9160-9","volume":"27","author":"JG Goetz","year":"2008","unstructured":"Goetz JG, Lajoie P, Wiseman SM, Nabi IR (2008) Caveolin-1 in tumor progression: the good, the bad and the ugly. Cancer Metastasis Rev 27:715\u2013735","journal-title":"Cancer Metastasis Rev"},{"key":"17090_CR46","first-page":"313","volume":"7","author":"I Gomez-Monterrey","year":"2012","unstructured":"Gomez-Monterrey I, Sala M, Musella S, Campiglia P (2012) Heat shock protein 90 inhibitors as therapeutic agents Recent patents on anti-cancer. Drug Discov 7:313\u2013336","journal-title":"Drug Discov"},{"key":"17090_CR47","first-page":"200","volume":"3","author":"P Gong","year":"2008","unstructured":"Gong P, Zhang X, Li J-h, Zhang G-c, Yang J, Cao L-l, Zhang J-z (2008) Observation of anti-tumor effect of Trichinella spiralis in mice on A549 lung cancer cell. J Pathogen Biol 3:200\u2013202","journal-title":"J Pathogen Biol"},{"key":"17090_CR48","doi-asserted-by":"crossref","unstructured":"Gottstein B, Soboslay P, Ortona E, Wang J, Siracusano A, Vuitton D (2017) Immunology of alveolar and cystic echinococcosis (AE and CE). In: Advances in parasitology, vol 96. Elsevier, pp 1-54","DOI":"10.1016\/bs.apar.2016.09.005"},{"key":"17090_CR49","doi-asserted-by":"crossref","unstructured":"Hafez EN, Moawed FS, Abdel-Hamid GR, Eldin ES (2020) Immunomodulatory activity of gamma radiation-attenuated Toxoplasma gondii in adjuvant arthritic mice J Photochem Photobiol B: Biol:111920","DOI":"10.1016\/j.jphotobiol.2020.111920"},{"key":"17090_CR50","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1084\/jem.20080108","volume":"205","author":"T Hagemann","year":"2008","unstructured":"Hagemann T et al (2008) Re-educating tumor-associated macrophages by targeting NF-\u03baB. J Exp Med 205:1261\u20131268","journal-title":"J Exp Med"},{"key":"17090_CR51","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","volume":"144","author":"D Hanahan","year":"2011","unstructured":"Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646\u2013674","journal-title":"Cell"},{"key":"17090_CR52","doi-asserted-by":"crossref","first-page":"765","DOI":"10.4049\/jimmunol.123.2.765","volume":"123","author":"M Hansson","year":"1979","unstructured":"Hansson M, K\u00e4rre K, Kiessling R, Roder J, Andersson B, H\u00e4yry P (1979) Natural NK-cell targets in the mouse thymus: characteristics of the sensitive cell population. J Immunol 123:765\u2013771","journal-title":"J Immunol"},{"key":"17090_CR53","doi-asserted-by":"publisher","first-page":"3406","DOI":"10.1098\/rstb.2011.0092","volume":"366","author":"BLJPTRSBBS Hart","year":"2011","unstructured":"Hart BLJPTRSBBS (2011) Behavioural defences in animals against pathogens and parasites: parallels with the pillars of medicine in humans. Philos Trans R Soc Lond B Biol Sci 366:3406\u20133417","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"17090_CR54","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.ijpara.2007.07.009","volume":"38","author":"R Hern\u00e1ndez-Bello","year":"2008","unstructured":"Hern\u00e1ndez-Bello R, Berm\u00fadez-Cruz RM, Fonseca-Li\u00f1\u00e1n R, Garc\u00eda-Reyna P, Le Guerhier F, Boireau P, Ortega-Pierres G (2008) Identification, molecular characterisation and differential expression of caveolin-1 in Trichinella spiralis maturing oocytes and embryos. Int J Parasitol 38:191\u2013202","journal-title":"Int J Parasitol"},{"key":"17090_CR55","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1093\/infdis\/124.6.587","volume":"124","author":"JB Hibbs Jr","year":"1971","unstructured":"Hibbs JB Jr, Lambert LH Jr, Remington JS (1971) Resistance to murine tumors conferred by chronic infection with intracellular protozoa, Toxoplasma gondii and Besnoitia jellisoni. J Infect Diseases 124:587\u2013592","journal-title":"J Infect Diseases"},{"key":"17090_CR56","doi-asserted-by":"publisher","first-page":"5878","DOI":"10.4049\/jimmunol.166.10.5878","volume":"166","author":"CA Hunter","year":"2001","unstructured":"Hunter CA et al (2001) Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis. J Immunol 166:5878\u20135881","journal-title":"J Immunol"},{"key":"17090_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.actatropica.2015.07.018","volume":"151","author":"AM Jansen","year":"2015","unstructured":"Jansen AM, Xavier SC, Roque ALR (2015) The multiple and complex and changeable scenarios of the Trypanosoma cruzi transmission cycle in the sylvatic environment. Acta Tropica 151:1\u201315","journal-title":"Acta Tropica"},{"key":"17090_CR58","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fcimb.2020.00010","volume":"10","author":"AM Jansen","year":"2020","unstructured":"Jansen AM, Xavier SCC, ALR R (2020) Landmarks of the knowledge and Trypanosoma cruzi biology in the wild environment. Front Cell Infection Microbiol 10:10","journal-title":"Front Cell Infection Microbiol"},{"key":"17090_CR59","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1083\/jcb.121.4.785","volume":"121","author":"DP Jasmer","year":"1993","unstructured":"Jasmer DP (1993) Trichinella spiralis infected skeletal muscle cells arrest in G2\/M and cease muscle gene expression. J Cell Biol 121:785\u2013793","journal-title":"J Cell Biol"},{"key":"17090_CR60","doi-asserted-by":"publisher","first-page":"e36245","DOI":"10.1371\/journal.pone.0036245","volume":"7","author":"C Junqueira","year":"2012","unstructured":"Junqueira C et al (2012) Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine. Plos One 7:e36245. https:\/\/doi.org\/10.1371\/journal.pone.0036245","journal-title":"Plos One"},{"key":"17090_CR61","doi-asserted-by":"publisher","first-page":"19695","DOI":"10.1073\/pnas.1110030108","volume":"108","author":"C Junqueira","year":"2011","unstructured":"Junqueira C et al (2011) Trypanosoma cruzi as an effective cancer antigen delivery vector. Proc Natl Acad Sci 108:19695\u201319700","journal-title":"Proc Natl Acad Sci"},{"key":"17090_CR62","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/S0167-5699(99)01547-9","volume":"20","author":"P Kali\u0144ski","year":"1999","unstructured":"Kali\u0144ski P, Hilkens CM, Wierenga EA, Kapsenberg ML (1999) T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol Today 20:561\u2013567","journal-title":"Immunol Today"},{"key":"17090_CR63","first-page":"72","volume":"63","author":"V Kallinikova","year":"2008","unstructured":"Kallinikova V, Batmonch Z, Kravtsov E, Karpenko L, Pachorukova L, Ogloblina T (2008) Antibodies against Trypanosoma cruzi accompanying the antitumoral action of lysed epimastigotes in vivo Moscow University. Biol Sci Bull 63:72\u201376","journal-title":"Biol Sci Bull"},{"key":"17090_CR64","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1023\/A:1016636419597","volume":"28","author":"VD Kallinikova","year":"2001","unstructured":"Kallinikova VD, Matekin PV, Ogloblina TA, Leikina MI, Kononenko AF, Sokolova NM, Pogodina LS (2001) Anticancer properties of flagellate protozoan Trypanosoma cruzi Chagas, 1909. Biol Bull 28:244\u2013255. https:\/\/doi.org\/10.1023\/A:1016636419597","journal-title":"Biol Bull"},{"key":"17090_CR65","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.vetpar.2013.02.021","volume":"196","author":"Y-J Kang","year":"2013","unstructured":"Kang Y-J et al (2013) Trichinella spiralis infection reduces tumor growth and metastasis of B16-F10 melanoma cells. Veterinary Parasitol 196:106\u2013113","journal-title":"Veterinary Parasitol"},{"key":"17090_CR66","doi-asserted-by":"publisher","first-page":"4701","DOI":"10.1007\/s11033-013-2565-8","volume":"40","author":"S Karadayi","year":"2013","unstructured":"Karadayi S, Arslan S, Sumer Z, Turan M, Sumer H, Karadayi K (2013) Does hydatid disease have protective effects against lung cancer? Mol Biol Reports 40:4701\u20134704","journal-title":"Mol Biol Reports"},{"key":"17090_CR67","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1038\/nrd4663","volume":"14","author":"HL Kaufman","year":"2015","unstructured":"Kaufman HL, Kohlhapp FJ, Zloza A (2015) Oncolytic viruses: a new class of immunotherapy drugs. Nature Rev Drug Discov 14:642\u2013662","journal-title":"Nature Rev Drug Discov"},{"key":"17090_CR68","doi-asserted-by":"publisher","first-page":"S38","DOI":"10.3346\/jkms.2007.22.S.S38","volume":"22","author":"J-O Kim","year":"2007","unstructured":"Kim J-O, Jung S-S, Kim S-Y, Kim TY, Shin D-W, Lee J-H, Lee Y-H (2007) Inhibition of Lewis lung carcinoma growth by Toxoplasma gondii through induction of Th1 immune responses and inhibition of angiogenesis. J Korean Med Sci 22:S38\u2013S46","journal-title":"J Korean Med Sci"},{"key":"17090_CR69","doi-asserted-by":"publisher","first-page":"3234","DOI":"10.1111\/jcmm.14207","volume":"23","author":"SG Kim","year":"2019","unstructured":"Kim SG, Seo SH, Shin JH, Yang JP, Lee SH, Shin EH (2019) Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53-dependent apoptosis and anticancer effect. J Cell Mol Med 23:3234\u20133245","journal-title":"J Cell Mol Med"},{"key":"17090_CR70","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1038\/sj.onc.1206196","volume":"22","author":"J-W Liu","year":"2003","unstructured":"Liu J-W et al (2003) Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene 22:1475\u20131485","journal-title":"Oncogene"},{"key":"17090_CR71","doi-asserted-by":"publisher","first-page":"583","DOI":"10.3892\/ol.2011.300","volume":"2","author":"M Liu","year":"2011","unstructured":"Liu M, Guo S, Stiles JK (2011) The emerging role of CXCL10 in cancer. Oncol Lett 2:583\u2013589","journal-title":"Oncol Lett"},{"key":"17090_CR72","doi-asserted-by":"publisher","first-page":"e730","DOI":"10.1371\/journal.pntd.0000730","volume":"4","author":"NC L\u00f3pez","year":"2010","unstructured":"L\u00f3pez NC et al (2010) Antiangiogenic and antitumor effects of Trypanosoma cruzi calreticulin. PLoS Negl Trop Dis 4:e730","journal-title":"PLoS Negl Trop Dis"},{"key":"17090_CR73","doi-asserted-by":"publisher","first-page":"104386","DOI":"10.1016\/j.micpath.2020.104386","volume":"147","author":"H Majidiani","year":"2020","unstructured":"Majidiani H, Dalimi A, Ghaffarifar F, Pirestani M, Ghaffari AD (2020) Computational probing of Toxoplasma gondii major surface antigen 1 (SAG1) for enhanced vaccine design against toxoplasmosis. Microbial Pathogenesis 147:104386","journal-title":"Microbial Pathogenesis"},{"key":"17090_CR74","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.bjid.2016.09.002","volume":"20","author":"H Majidiani","year":"2016","unstructured":"Majidiani H, Dalvand S, Daryani A, Galvan-Ramirez ML, Foroutan-Rad M (2016) Is chronic toxoplasmosis a risk factor for diabetes mellitus? A systematic review and meta-analysis of case-control studies. Brazilian J Infectious Dis 20:605\u2013609","journal-title":"Brazilian J Infectious Dis"},{"key":"17090_CR75","doi-asserted-by":"crossref","unstructured":"Mantovani A, Allavena P, Sica A, Balkwill F (2008) Cancer-related inflammation nature 454:436-444","DOI":"10.1038\/nature07205"},{"key":"17090_CR76","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1017\/S0031182009005861","volume":"136","author":"A Marcili","year":"2009","unstructured":"Marcili A et al (2009) A new genotype of Trypanosoma cruzi associated with bats evidenced by phylogenetic analyses using SSU rDNA, cytochrome b and Histone H2B genes and genotyping based on ITS1 rDNA. Parasitology 136:641\u2013655","journal-title":"Parasitology"},{"key":"17090_CR77","doi-asserted-by":"crossref","unstructured":"Maurice AP, Jenkin A, Norton RE, Hamilton A, Ho Y-H (2020) Epidemiology of parasitic diseases. In: The Surgical Management of Parasitic Diseases. Springer, pp 3-21","DOI":"10.1007\/978-3-030-47948-0_1"},{"key":"17090_CR78","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1023\/B:BEBM.0000038157.69208.27","volume":"137","author":"V Mel'nikov","year":"2004","unstructured":"Mel'nikov V, Velasko FF, Dobrovinskaya O (2004) Suppression of growth and metastasizing of T-cell lymphoma in mice infected with American trypanosomiasis at different stages of experimental infection. Bull Exp Biol Med 137:475\u2013478","journal-title":"Bull Exp Biol Med"},{"key":"17090_CR79","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.chom.2014.02.011","volume":"15","author":"EA Mesri","year":"2014","unstructured":"Mesri EA, Feitelson MA, Munger K (2014) Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe 15:266\u2013282","journal-title":"Cell Host Microbe"},{"key":"17090_CR80","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1042\/bj3440281","volume":"344","author":"M Michalak","year":"1999","unstructured":"Michalak M, Corbett EF, Mesaeli N, Nakamura K, Opas M (1999) Calreticulin: one protein, one gene, many functions. Biochem J 344:281\u2013292","journal-title":"Biochem J"},{"key":"17090_CR81","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1292\/jvms.54.221","volume":"54","author":"K Miyahara","year":"1992","unstructured":"Miyahara K et al (1992a) Antitumor activity of Toxoplasma lysate antigen against methylcholanthrene-induced tumor-bearing rats. J Veterinary Med Sci 54:221\u2013228. https:\/\/doi.org\/10.1292\/jvms.54.221","journal-title":"J Veterinary Med Sci"},{"key":"17090_CR82","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1292\/jvms.54.7","volume":"54","author":"K Miyahara","year":"1992","unstructured":"Miyahara K et al (1992b) Therapeutic effects of Toxoplasma lysate antigen on 20-methylcholanthrene-induced BALB\/c mouse tumors. J Vet Med Sci 54:7\u201312","journal-title":"J Vet Med Sci"},{"key":"17090_CR83","doi-asserted-by":"publisher","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J PLoS Med 6:e1000097","journal-title":"J PLoS Med"},{"key":"17090_CR84","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.molbiopara.2004.12.014","volume":"140","author":"MC Molina","year":"2005","unstructured":"Molina MC et al (2005) An in vivo role for Trypanosoma cruzi calreticulin in antiangiogenesis. Mol Biochem Parasitol 140:133\u2013140","journal-title":"Mol Biochem Parasitol"},{"key":"17090_CR85","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1159\/000231956","volume":"55","author":"J Molinari","year":"1977","unstructured":"Molinari J, Ebersole J (1977) Antineoplastic effects of long-term Trichinella spiralis infection on B-16 melanoma. Int Archives Allergy Immunol 55:444\u2013448","journal-title":"Int Archives Allergy Immunol"},{"key":"17090_CR86","doi-asserted-by":"publisher","first-page":"103752","DOI":"10.1016\/j.micpath.2019.103752","volume":"137","author":"A Najafi","year":"2019","unstructured":"Najafi A et al (2019) Is there association between Trichomonas vaginalis infection and prostate cancer risk?: A systematic review and meta-analysis J. Microbial Pathogenesis 137:103752","journal-title":"Microbial Pathogenesis"},{"key":"17090_CR87","doi-asserted-by":"crossref","unstructured":"Newman JH, Zloza A (2017) Infection: a cause of and cure for cancer Current Pharmacol Reports 3:315-320","DOI":"10.1007\/s40495-017-0109-y"},{"key":"17090_CR88","doi-asserted-by":"publisher","first-page":"3131","DOI":"10.1093\/nar\/29.15.3131","volume":"29","author":"E Nicolas","year":"2001","unstructured":"Nicolas E, Ait-Si-Ali S, Trouche D (2001) The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein. Nucleic Acids Res 29:3131\u20133136","journal-title":"Nucleic Acids Res"},{"key":"17090_CR89","doi-asserted-by":"crossref","unstructured":"Nourmohammadi H et al. (2020) Multi-epitope vaccine against cystic echinococcosis using immunodominant epitopes from EgA31 and EgG1Y162 antigens Informatics in Medicine Unlocked:100464","DOI":"10.1016\/j.imu.2020.100464"},{"key":"17090_CR90","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3892\/ijo.2013.2000","volume":"43","author":"V Noya","year":"2013","unstructured":"Noya V et al (2013) Mucin-like peptides from Echinococcus granulosus induce antitumor activity. Int J Oncol 43:775\u2013784","journal-title":"Int J Oncol"},{"key":"17090_CR91","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1292\/jvms1939.47.225","volume":"47","author":"R Ogawa","year":"1985","unstructured":"Ogawa R, Sato M, Hirose T, Suzuki N (1985) Preventive effect of inoculation with Toxoplasma lysate antigen (TLA) on fatal infection with mouse piroplasma. Japanese J Vet Sci 47:225\u2013236","journal-title":"Japanese J Vet Sci"},{"key":"17090_CR92","doi-asserted-by":"publisher","first-page":"2834","DOI":"10.1158\/1078-0432.CCR-12-3661","volume":"19","author":"K Oikonomopoulou","year":"2013","unstructured":"Oikonomopoulou K, Brinc D, Kyriacou K, Diamandis EP (2013) Infection and cancer: revaluation of the hygiene hypothesis. J Clin Cancer Res 19:2834\u20132841","journal-title":"J Clin Cancer Res"},{"key":"17090_CR93","first-page":"362","volume":"244","author":"Y Omata","year":"1979","unstructured":"Omata Y, Nakabayashi T, Suzuki N (1979) Different appearance of parasitized erythrocytes in blood between normal and toxoplasma-infected rats after infection of Plasmodium berghei Zentralblatt fur Bakteriologie. Parasitenkunde, Infektionskrankheiten und Hygiene 244:362\u2013373","journal-title":"Parasitenkunde, Infektionskrankheiten und Hygiene"},{"key":"17090_CR94","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3389\/fphar.2013.00057","volume":"4","author":"MO Palumbo","year":"2013","unstructured":"Palumbo MO et al (2013) Systemic cancer therapy: achievements and challenges that lie ahead. Front Pharmacol 4:57","journal-title":"Front Pharmacol"},{"key":"17090_CR95","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/nrm2122","volume":"8","author":"RG Parton","year":"2007","unstructured":"Parton RG, Simons K (2007) The multiple faces of caveolae. Nature Rev Mol Cell Biol 8:185\u2013194","journal-title":"Nature Rev Mol Cell Biol"},{"key":"17090_CR96","doi-asserted-by":"publisher","first-page":"171","DOI":"10.3347\/kjp.2010.48.2.171","volume":"48","author":"K-H Pyo","year":"2010","unstructured":"Pyo K-H, Jung B-K, Chai J-Y, Shin E-H (2010) Suppressed CD31 expression in sarcoma-180 tumors after injection with Toxoplasma gondii lysate antigen in BALB\/c mice. Korean J Parasitol 48:171","journal-title":"Korean J Parasitol"},{"key":"17090_CR97","doi-asserted-by":"publisher","first-page":"605","DOI":"10.3347\/kjp.2014.52.6.605","volume":"52","author":"K-H Pyo","year":"2014","unstructured":"Pyo K-H, Jung B-K, Xin C-F, Lee Y-W, Chai J-Y, Shin E-H (2014) Prominent IL-12 production and tumor reduction in athymic nude mice after Toxoplasma gondii lysate antigen treatment. Korean J Parasitol 52:605","journal-title":"Korean J Parasitol"},{"key":"17090_CR98","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1038\/nm.3394","volume":"19","author":"DF Quail","year":"2013","unstructured":"Quail DF, Joyce JA (2013) Microenvironmental regulation of tumor progression and metastasis. Nature Med 19:1423\u20131437","journal-title":"Nature Med"},{"key":"17090_CR99","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1111\/apm.13018","volume":"128","author":"MP Quintana","year":"2020","unstructured":"Quintana MP, Smith-Togobo C, Moormann A, Hviid L (2020) Endemic Burkitt lymphoma\u2013an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites. J Apmis 128:129\u2013135","journal-title":"J Apmis"},{"key":"17090_CR100","doi-asserted-by":"publisher","first-page":"268","DOI":"10.3389\/fimmu.2016.00268","volume":"7","author":"G Ram\u00edrez-Toloza","year":"2016","unstructured":"Ram\u00edrez-Toloza G, Abello P, Ferreira A (2016) Is the antitumor property of Trypanosoma cruzi infection mediated by its calreticulin? Front Immunol 7:268","journal-title":"Front Immunol"},{"key":"17090_CR101","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/zph.12094","volume":"61","author":"J Ram\u00edrez","year":"2014","unstructured":"Ram\u00edrez J, Hern\u00e1ndez C, Montilla M, Zambrano P, Fl\u00f3rez A, Parra E, Cucunub\u00e1 Z (2014) First report of human Trypanosoma cruzi infection attributed to TcBat genotype. Zoonoses Public health 61:477\u2013479","journal-title":"Zoonoses Public health"},{"key":"17090_CR102","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1097\/01.mcp.0000145791.13714.ae","volume":"11","author":"CD Ramsey","year":"2005","unstructured":"Ramsey CD, Celed\u00f3n JC (2005) The hygiene hypothesis and asthma. J Current Opinion Pulmon Med 11:14\u201320","journal-title":"J Current Opinion Pulmon Med"},{"key":"17090_CR103","doi-asserted-by":"publisher","first-page":"e0200433","DOI":"10.1371\/journal.pone.0200433","volume":"13","author":"SL Ranasinghe","year":"2018","unstructured":"Ranasinghe SL, Boyle GM, Fischer K, Potriquet J, Mulvenna JP, McManus DP (2018) Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer. PloS one 13:e0200433","journal-title":"PloS one"},{"key":"17090_CR104","doi-asserted-by":"publisher","first-page":"e0004268","DOI":"10.1371\/journal.pntd.0004268","volume":"9","author":"SL Ranasinghe","year":"2015","unstructured":"Ranasinghe SL, Fischer K, Zhang W, Gobert GN, McManus DP (2015) Cloning and characterization of two potent Kunitz type protease inhibitors from Echinococcus granulosus. PLoS Neglect Trop Diseases 9:e0004268","journal-title":"PLoS Neglect Trop Diseases"},{"key":"17090_CR105","doi-asserted-by":"publisher","first-page":"2631","DOI":"10.1242\/jcs.01245","volume":"117","author":"U Rescher","year":"2004","unstructured":"Rescher U, Gerke V (2004) Annexins\u2013unique membrane binding proteins with diverse functions. J Cell Sci 117:2631\u20132639","journal-title":"J Cell Sci"},{"key":"17090_CR106","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2567.2008.03007.x","volume":"126","author":"GAJI Rook","year":"2009","unstructured":"Rook GAJI (2009) Review series on helminths, immune modulation and the hygiene hypothesis: the broader implications of the hygiene hypothesis. J Immunology 126:3\u201311","journal-title":"J Immunology"},{"key":"17090_CR107","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1007\/BF01625403","volume":"34","author":"G Roskin","year":"1931","unstructured":"Roskin G, Exempliarskaia E (1931) Protozoeninfektion und experimenteller. Krebs Zeitschrift f\u00fcr Krebsforschung 34:628\u2013645","journal-title":"Krebs Zeitschrift f\u00fcr Krebsforschung"},{"key":"17090_CR108","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.fm.2016.12.012","volume":"64","author":"A Rostami","year":"2017","unstructured":"Rostami A, Gamble HR, Dupouy-Camet J, Khazan H, Bruschi F (2017) Meat sources of infection for outbreaks of human trichinellosis. Food Microbiol 64:65\u201371","journal-title":"Food Microbiol"},{"key":"17090_CR109","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.foodcont.2018.04.028","volume":"91","author":"A Rostami","year":"2018","unstructured":"Rostami A, Riahi SM, Ghadimi R, Hanifehpour H, Hamidi F, Khazan H, Gamble HR (2018) A systematic review and meta-analysis on the global seroprevalence of Trichinella infection among wild boars. Food Control 91:404\u2013411","journal-title":"Food Control"},{"key":"17090_CR110","first-page":"S120","volume":"50","author":"S Rostamirad","year":"2017","unstructured":"Rostamirad S, Darani HY (2017) Anti tumor activity of a fraction of hydatid cyst fluid on colon cancer growth tumor in animal model. Int J Antimicrobial Agents 50:S120\u2013S120","journal-title":"Int J Antimicrobial Agents"},{"key":"17090_CR111","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/S0934-8840(89)80060-X","volume":"271","author":"A Saito","year":"1989","unstructured":"Saito A et al (1989) Inhibitory effect of Toxoplasma lysate antigen on the multiplication of transplanted tumor in mice. Zentralblatt f\u00fcr Bakteriologie 271:114\u2013126","journal-title":"Zentralblatt f\u00fcr Bakteriologie"},{"key":"17090_CR112","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1292\/jvms1939.47.921","volume":"47","author":"M Sato","year":"1985","unstructured":"Sato M, Hori Z, Hirose T, Suzuki N (1985) Immune effect of Toxoplasma lysate antigen (TLA) on cattle against Theileria sergenti infection. Japanese J Vet Sci 47:921\u2013929","journal-title":"Japanese J Vet Sci"},{"key":"17090_CR113","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.tree.2008.02.011","volume":"23","author":"PJTE Schmid-Hempel","year":"2008","unstructured":"Schmid-Hempel PJTE (2008) Parasite immune evasion: a momentous molecular war. J Trends Ecol Evol 23:318\u2013326","journal-title":"J Trends Ecol Evol"},{"key":"17090_CR114","doi-asserted-by":"publisher","first-page":"90","DOI":"10.4236\/abcr.2016.52010","volume":"5","author":"SM Sharafi","year":"2016","unstructured":"Sharafi SM, Rafiei R, Rafiei R, Hadipour M, Shirzad H, Khanahmad H, Darani HY (2016) A nonglycosylated 27 kDa molecule as common antigen between human breast cancer and Echinococcus granulosus hydatid cyst wall. Advances Breast Cancer Res 5:90","journal-title":"Advances Breast Cancer Res"},{"key":"17090_CR115","first-page":"57","volume":"12","author":"SM Sharafi","year":"2018","unstructured":"Sharafi SM, Shirzad H, Khanahmad H, Ataei B, Darani HY (2018) Monoclonal antibodies production against a 40KDa band of hydatid cyst fluid. Recent Patents Biotechnol 12:57\u201364","journal-title":"Recent Patents Biotechnol"},{"key":"17090_CR116","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1023\/A:1023466517225","volume":"135","author":"L Sheklakova","year":"2003","unstructured":"Sheklakova L, Kallinikova V, Karpenko L (2003) Genetic heterogeneity of Trypanosoma cruzi and its direct anticancer effect in cultured human tumor cells. Bull Exp Biol Med 135:89","journal-title":"Bull Exp Biol Med"},{"key":"17090_CR117","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1007\/s10096-016-2734-5","volume":"35","author":"MN Shiadeh","year":"2016","unstructured":"Shiadeh MN et al (2016) The correlation between Toxoplasma gondii infection and prenatal depression in pregnant women. Eur J Clin Microbiol Infect Diseases 35:1829\u20131835","journal-title":"Eur J Clin Microbiol Infect Diseases"},{"key":"17090_CR118","first-page":"5","volume":"65","author":"RL Siegel","year":"2015","unstructured":"Siegel RL, Miller KD, Jemal AJC (2015) Cancer Stat 65:5","journal-title":"Cancer Stat"},{"key":"17090_CR119","doi-asserted-by":"crossref","unstructured":"Sofronic-Milosavljevic L, Ilic N, Pinelli E, Gruden-Movsesijan A (2015) Secretory products of Trichinella spiralis muscle larvae and immunomodulation: implication for autoimmune diseases, allergies, and malignancies. J Immunol Res","DOI":"10.1155\/2015\/523875"},{"key":"17090_CR120","doi-asserted-by":"crossref","unstructured":"Strachan DPJBBMJ (1989) Hay fever, hygiene, and household size 299:1259","DOI":"10.1136\/bmj.299.6710.1259"},{"key":"17090_CR121","doi-asserted-by":"publisher","first-page":"d208","DOI":"10.2741\/A275","volume":"3","author":"JE Trosko","year":"1998","unstructured":"Trosko JE, Ruch RJ (1998) Cell-cell communication in carcinogenesis. J Front Biosci 3:d208\u2013d236","journal-title":"J Front Biosci"},{"key":"17090_CR122","doi-asserted-by":"publisher","unstructured":"Upadhyay A (2020) Cancer: an unknown territory; rethinking before going ahead. Genes Diseases. https:\/\/doi.org\/10.1016\/j.gendis.2020.09.002","DOI":"10.1016\/j.gendis.2020.09.002"},{"key":"17090_CR123","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1158\/2326-6066.CIR-13-0179","volume":"2","author":"N Vandeven","year":"2014","unstructured":"Vandeven N, Nghiem P (2014) Pathogen-driven cancers and emerging immune therapeutic strategies. J Cancer Immunol Res 2:9\u201314","journal-title":"J Cancer Immunol Res"},{"key":"17090_CR124","doi-asserted-by":"publisher","first-page":"42","DOI":"10.5114\/ceji.2015.50832","volume":"40","author":"S Vasilev","year":"2015","unstructured":"Vasilev S, Ilic N, Gruden-Movsesijan A, Vasilijic S, Bosic M, Sofronic-Milosavljevic L (2015) Necrosis and apoptosis in Trichinella spiralis-mediated tumour reduction. Central-European J Immunol 40:42","journal-title":"Central-European J Immunol"},{"key":"17090_CR125","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.3390\/cancers12082237","volume":"12","author":"S Vivarelli","year":"2020","unstructured":"Vivarelli S, Falzone L, Grillo CM, Scandurra G, Torino F, Libra M (2020) Cancer management during COVID-19 pandemic: is immune checkpoint inhibitors-based immunotherapy harmful or beneficial? Cancers 12:2237","journal-title":"Cancers"},{"key":"17090_CR126","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.actatropica.2009.01.003","volume":"110","author":"S Wang","year":"2009","unstructured":"Wang S et al (2009a) Molecular cloning and characterization of heat shock protein 70 from Trichinella spiralis. Acta Tropica 110:46\u201351","journal-title":"Acta Tropica"},{"key":"17090_CR127","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1089\/cbr.2011.1135","volume":"27","author":"X-P Wang","year":"2012","unstructured":"Wang X-P, Lin H-P, Wang Q-X, Gu Y (2012) Specific antitumor immunity induced by cross-linking complex heat shock protein 72 and alpha-fetoprotein. Cancer Biotherapy Radiopharmaceuticals 27:189\u2013197","journal-title":"Cancer Biotherapy Radiopharmaceuticals"},{"key":"17090_CR128","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.vetpar.2008.10.052","volume":"159","author":"X Wang","year":"2009","unstructured":"Wang X et al (2009b) Trichinella spiralis\u2014a potential anti-tumor agent. Vet Parasitol 159:249\u2013252","journal-title":"Vet Parasitol"},{"key":"17090_CR129","first-page":"1137","volume":"10","author":"X Wang","year":"2019","unstructured":"Wang X, Guan W, Zhang X, Zhang J (2019) Employing parasite against cancer: a lesson from the canine tapeworm. Echinococcus Granulocus Front Pharmacol 10:1137","journal-title":"Echinococcus Granulocus Front Pharmacol"},{"key":"17090_CR130","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.vetpar.2013.01.052","volume":"194","author":"X Wang","year":"2013","unstructured":"Wang X et al (2013) An anti-tumor protein produced by Trichinella spiralis induces apoptosis in human hepatoma H7402 cells. Vet Parasitol 194:186\u2013188","journal-title":"Vet Parasitol"},{"key":"17090_CR131","doi-asserted-by":"crossref","unstructured":"Weatherly NF (1970) Increased survival of Swiss mice given sublethal infections of Trichinella spiralis J Parasitol:748-752","DOI":"10.2307\/3277722"},{"key":"17090_CR132","doi-asserted-by":"crossref","unstructured":"Wen H, Vuitton L, Tuxun T, Li J, Vuitton DA, Zhang W, McManus DP (2019) Echinococcosis: advances in the 21st century. Clin Microbiol Rev 32","DOI":"10.1128\/CMR.00075-18"},{"key":"17090_CR133","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1097\/01.cji.0000211316.15278.6e","volume":"30","author":"A Wesa","year":"2007","unstructured":"Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ (2007) Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother 30:75\u201382","journal-title":"J Immunother"},{"key":"17090_CR134","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1017\/S0031182004006912","volume":"130","author":"Z Wu","year":"2005","unstructured":"Wu Z, Nagano I, Boonmars T, Takahashi Y (2005) A spectrum of functional genes mobilized after Trichinella spiralis infection in skeletal muscle. Parasitology 130:561","journal-title":"Parasitology"},{"key":"17090_CR135","doi-asserted-by":"publisher","first-page":"2164","DOI":"10.3389\/fmicb.2017.02164","volume":"8","author":"Z Wu","year":"2017","unstructured":"Wu Z, Wang L, Tang Y, Sun XJF (2017) Parasite-derived proteins for the treatment of allergies and autoimmune diseases. Front Microbiol 8:2164","journal-title":"Front Microbiol"},{"key":"17090_CR136","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1136\/bmj.1.6176.1463-a","volume":"1","author":"W Yong","year":"1979","unstructured":"Yong W, Heath D, Savage T (1979) Possible antigenic similarity between pulmonary carcinoma and cysts of Echinococcus granulosus. British Med J 1:1463","journal-title":"British Med J"},{"key":"17090_CR137","first-page":"107","volume":"1","author":"H Yousofi Darani","year":"2019","unstructured":"Yousofi Darani H, Jafaei Nodeh F, Ramazaninia ST, Sharafi SM (2019) Effect of immune responses against hydatid cyst antigens on growth of melanoma tumor. Immunoregulation 1:107\u2013112","journal-title":"Immunoregulation"},{"key":"17090_CR138","doi-asserted-by":"crossref","unstructured":"Yousofi Darani H, Soozangar N, Khorami S, Taji F, Yousofi M, Shirzad H (2012) Hydatid cyst protoscolices induce cell death in WEHI-164 fibrosarcoma cells and inhibit the proliferation of baby hamster kidney fibroblasts in vitro. J Parasitol Res","DOI":"10.1155\/2012\/304183"},{"key":"17090_CR139","first-page":"5","volume":"38","author":"MM Zaiss","year":"2016","unstructured":"Zaiss MM, Harris NLJP (2016) Interactions between the intestinal microbiome and helminth. Parasites 38:5\u201311","journal-title":"Parasites"},{"key":"17090_CR140","doi-asserted-by":"publisher","first-page":"651","DOI":"10.7150\/ijbs.7.651","volume":"7","author":"BF Zamarron","year":"2011","unstructured":"Zamarron BF, Chen W (2011) Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci 7:651","journal-title":"Int J Biol Sci"},{"key":"17090_CR141","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s10517-008-0089-3","volume":"145","author":"A Zenina","year":"2008","unstructured":"Zenina A et al (2008) The study of immunological component in antitumor effect of Trypanosoma cruzi. Bull Exp Biol Med 145:352\u2013354","journal-title":"Bull Exp Biol Med"},{"key":"17090_CR142","doi-asserted-by":"publisher","first-page":"6679","DOI":"10.4049\/jimmunol.181.10.6679","volume":"181","author":"W Zhang","year":"2008","unstructured":"Zhang W, Ross AG, DP MM (2008) Mechanisms of immunity in hydatid disease: implications for vaccine development. J Immunol 181:6679\u20136685","journal-title":"J Immunol"},{"key":"17090_CR143","doi-asserted-by":"publisher","first-page":"857","DOI":"10.3892\/ijo.2016.3616","volume":"49","author":"X Zhang","year":"2016","unstructured":"Zhang X, Zhang W, Yuan X, Fu M, Qian H, Xu W (2016) Neutrophils in cancer development and progression: roles, mechanisms, and implications. Int J Oncol 49:857\u2013867","journal-title":"Int J Oncol"},{"key":"17090_CR144","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1242\/jcs.02821","volume":"119","author":"XH Zhang","year":"2006","unstructured":"Zhang XH, Zhao C, Seleznev K, Song K, Manfredi JJ, Ma ZA (2006) Disruption of G1-phase phospholipid turnover by inhibition of Ca2+-independent phospholipase A2 induces a p53-dependent cell-cycle arrest in G1 phase. J Cell Sci 119:1005\u20131015","journal-title":"J Cell Sci"},{"key":"17090_CR145","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1590\/S0074-02762009000700021","volume":"104","author":"B Zingales","year":"2009","unstructured":"Zingales B et al (2009) A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI. Memorias do Instituto Oswaldo Cruz 104:1051\u20131054","journal-title":"Memorias do Instituto Oswaldo Cruz"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-17090-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-021-17090-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-021-17090-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T09:13:13Z","timestamp":1700212393000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-021-17090-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,11]]},"references-count":145,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["17090"],"URL":"https:\/\/doi.org\/10.1007\/s11356-021-17090-5","relation":{},"ISSN":["0944-1344","1614-7499"],"issn-type":[{"value":"0944-1344","type":"print"},{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,11]]},"assertion":[{"value":"5 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 October 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This work was approved by the Ethics Committee of Ilam University of Medical Sciences (IR.MEDILAM.REC.1399.333).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}