{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T23:07:23Z","timestamp":1773702443332,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"14","license":[{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:00:00Z","timestamp":1672963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Science and Technology Project of Hebei Education Department","award":["ZD2020113"],"award-info":[{"award-number":["ZD2020113"]}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["H2020209250"],"award-info":[{"award-number":["H2020209250"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073589"],"award-info":[{"award-number":["82073589"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"DOI":"10.1007\/s11356-022-25109-8","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T09:06:35Z","timestamp":1672995995000},"page":"40162-40173","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus"],"prefix":"10.1007","volume":"30","author":[{"given":"Weixuan","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1207-7251","authenticated-orcid":false,"given":"Yanshu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"key":"25109_CR1","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/fcp.12193","volume":"30","author":"WH Bian","year":"2016","unstructured":"Bian WH, An YK, Qu HQ, Yang Y, Yang JH, Xu YY (2016) Allyl-isatin suppresses cell viability, induces cell cycle arrest, and promotes cell apoptosis in hepatocellular carcinoma HepG2 cells. Fundam Clin Pharmacol 30:253\u2013262","journal-title":"Fundam Clin Pharmacol"},{"key":"25109_CR2","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/JLB.2MR0220-549R","volume":"108","author":"TM Bui","year":"2020","unstructured":"Bui TM, Wiesolek HL, Sumagin R (2020) ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis. J Leukoc Biol 108:787\u2013799","journal-title":"J Leukoc Biol"},{"key":"25109_CR3","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1039\/c9mt00151d","volume":"12","author":"YH Cao","year":"2020","unstructured":"Cao YH, Wang D, Li QZ, Liu HJ, Jin CH, Yang JH, Wu SW, Lu XB, Cai Y (2020) Activation of Nrf2 by lead sulfide nanoparticles induces impairment of learning and memory. Metallomics 12:34\u201341","journal-title":"Metallomics"},{"key":"25109_CR4","first-page":"10","volume":"23","author":"YH Chen","year":"2022","unstructured":"Chen YH, Lightman S, Eskandarpour M, Calder VL (2022) Adhesion molecule targeted therapy for non-infectious uveitis. Int J Mol Sci 23:10","journal-title":"Int J Mol Sci"},{"issue":"6","key":"25109_CR5","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1089\/ars.2010.3522","volume":"15","author":"JM Cook-Mills","year":"2011","unstructured":"Cook-Mills JM, Marchese ME, Abdala-Valencia H (2011) Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants. Antioxidants & Redox Signaling 15(6):1607\u20131638. https:\/\/doi.org\/10.1089\/ars.2010.3522","journal-title":"Antioxidants & Redox Signaling"},{"key":"25109_CR6","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1093\/neuonc\/noz169","volume":"22","author":"A Corroyer-Dulmont","year":"2020","unstructured":"Corroyer-Dulmont A, Valable S, Falzone N, Frelin-Labalme AM, Tietz O, Toutain J, Soto MS, Chazalviel DDL, Peres EA, Sibson NR, Vallis KA, Bernaudin M (2020) VCAM-1 targeted alpha-particle therapy for early brain metastases. Neuro-Oncol 22:357\u2013368","journal-title":"Neuro-Oncol"},{"key":"25109_CR7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.tox.2020.152545","volume":"442","author":"A Deciga-Alcaraz","year":"2020","unstructured":"Deciga-Alcaraz A, Medina-Reyes EI, Delgado-Buenrostro NL, Rodriguez-Ibarra C, Ganem-Rondero A, Vazquez-Zapien GJ, Mata-Miranda MM, Limon-Pacheco JH, Garcia-Cuellar CM, Sanchez-Perez Y, Chirino YI (2020) Toxicity of engineered nanomaterials with different physicochemical properties and the role of protein corona on cellular uptake and intrinsic ROS production. Toxicology 442:16","journal-title":"Toxicology"},{"key":"25109_CR8","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.drudis.2015.05.003","volume":"20","author":"D Demeestere","year":"2015","unstructured":"Demeestere D, Libert C, Vandenbroucke RE (2015) Clinical implications of leukocyte infiltration at the choroid plexus in (neuro)inflammatory disorders. Drug Discov Today 20:928\u2013941","journal-title":"Drug Discov Today"},{"key":"25109_CR9","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s12989-017-0236-y","volume":"14","author":"J Dumkova","year":"2017","unstructured":"Dumkova J, Smutna T, Vrlikova L, Le Coustumer P, Vecera Z, Docekal B, Mikuska P, Capka L, Fictum P, Hampl A, Buchtova M (2017) Sub-chronic inhalation of lead oxide nanoparticles revealed their broad distribution and tissue-specific subcellular localization in target organs. Part Fibre Toxicol 14:19","journal-title":"Part Fibre Toxicol"},{"key":"25109_CR10","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.nrl.2018.10.004","volume":"37","author":"S Garfias","year":"2022","unstructured":"Garfias S, Dominguez BT, Rojas AT, Arroyo M, Rodriguez U, Boll C, Sosa AL, Sciutto E, Adalid-Peralta L, Lopez YM, Fragoso G, Fleury A (2022) Peripheral blood lymphocyte phenotypes in Alzheimer and Parkinson\u2019s diseases. Neurologia 37:110\u2013121","journal-title":"Neurologia"},{"key":"25109_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4077\/CJP.2017.BAF435","volume":"60","author":"Z Goc","year":"2017","unstructured":"Goc Z, Szaroma W, Kapusta E, Dziubek K (2017) Protective effects of melatonin on the activity of SOD, CAT, GSH-Px and GSH content in organs of mice after administration of SNP. Chin J Physiol 60:1\u201310","journal-title":"Chin J Physiol"},{"key":"25109_CR12","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1016\/j.ijpara.2020.07.007","volume":"50","author":"NT Ha","year":"2020","unstructured":"Ha NT, Sasaki T, Suzue K, Yokoo H, Isoda K, Kamitani W, Shimokawa C, Hisaeda H, Imai T (2020) Blood-cerebrospinal fluid barrier: another site disrupted during experimental cerebral malaria caused by Plasmodium berghei ANKA. Int J Parasitol 50:1167\u20131175","journal-title":"Int J Parasitol"},{"key":"25109_CR13","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.bbi.2019.01.024","volume":"79","author":"WW Huo","year":"2019","unstructured":"Huo WW, Liu Y, Lei YS, Zhang Y, Huang YL, Mao YT, Wang CC, Sun Y, Zhang W, Ma ZL, Gu XP (2019) Imbalanced spinal infiltration of Th17\/Treg cells contributes to bone cancer pain via promoting microglial activation. Brain Behav Immun 79:139\u2013151","journal-title":"Brain Behav Immun"},{"key":"25109_CR14","doi-asserted-by":"publisher","first-page":"E867","DOI":"10.1212\/WNL.0000000000006082","volume":"91","author":"S Janelidze","year":"2018","unstructured":"Janelidze S, Mattsson N, Stomrud E, Lindberg O, Palmqvist S, Zetterberg H, Blennow K, Hansson O (2018) CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease. Neurology 91:E867\u2013E877","journal-title":"Neurology"},{"key":"25109_CR15","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1080\/17435390.2018.1438679","volume":"12","author":"J Lebedova","year":"2018","unstructured":"Lebedova J, Novakova Z, Vecera Z, Buchtova M, Dumkova J, Docekal B, Blahova L, Mikuska P, Misek I, Hampl A, Hilscherova K (2018) Impact of acute and subchronic inhalation exposure to PbO nanoparticles on mice. Nanotoxicology 12:290\u2013304","journal-title":"Nanotoxicology"},{"key":"25109_CR16","doi-asserted-by":"crossref","unstructured":"Lee S, Chung J, Ha IS, Yi K, Lee JE, Kang HG, Choi I, Oh KH, Kim JY, Surh CD, Ahn C (2007) Hydrogen peroxide increases human leukocyte adhesion to porcine aortic endothelial cells via NF&nbsp;B-dependent up-regulation of VCAM-1. International Immunology 19(12):1349\u20131359","DOI":"10.1093\/intimm\/dxm104"},{"key":"25109_CR17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.etap.2019.03.010","volume":"68","author":"JW Lee","year":"2019","unstructured":"Lee JW, Choi H, Hwang UK, Kang JC, Kang YJ, Kim KI, Kim JH (2019) Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: a review. Environ Toxicol Pharmacol 68:101\u2013108","journal-title":"Environ Toxicol Pharmacol"},{"key":"25109_CR18","doi-asserted-by":"publisher","first-page":"15686","DOI":"10.1016\/j.ceramint.2020.03.119","volume":"46","author":"ME Mahmoud","year":"2020","unstructured":"Mahmoud ME, El-Khatib AM, Halbas AM, El-Sharkawy RM (2020) Investigation of physical, mechanical and gamma-ray shielding properties using ceramic tiles incorporated with powdered lead oxide. Ceram Int 46:15686\u201315694","journal-title":"Ceram Int"},{"issue":"8","key":"25109_CR19","doi-asserted-by":"publisher","first-page":"301","DOI":"10.3390\/biom9080301","volume":"9","author":"K Malekmohammad","year":"2019","unstructured":"Malekmohammad K, Sewell RDE, Rafieian-Kopaei M (2019) Antioxidants and atherosclerosis: mechanistic aspects. Biomolecules 9(8):301. https:\/\/doi.org\/10.3390\/biom9080301","journal-title":"Biomolecules"},{"key":"25109_CR20","doi-asserted-by":"publisher","first-page":"109740","DOI":"10.1016\/j.msec.2019.109740","volume":"103","author":"W Muhammad","year":"2019","unstructured":"Muhammad W, Khan MA, Nazir M, Siddiquah A, Mushtaq S, Hashmi SS, Abbasi BH (2019) Papaver somniferum L. mediated novel bioinspired lead oxide (PbO) and iron oxide (Fe2O3) nanoparticles: in-vitro biological applications, biocompatibility and their potential towards HepG2 cell line. Mater Sci Eng C-Mater Biol Appl 103:109740","journal-title":"Mater Sci Eng C-Mater Biol Appl"},{"key":"25109_CR21","series-title":"Annual review of pathology-mechanisms of disease","first-page":"323","volume-title":"Annual Review of pathology: mechanisms of disease","author":"WA Muller","year":"2011","unstructured":"Muller WA (2011) Mechanisms of leukocyte transendothelial migration. In: Abbas AK, Galli SJ, Howley PM (eds) Annual Review of pathology: mechanisms of disease, vol 6. Annual review of pathology-mechanisms of disease. Annual Reviews, Palo Alto, pp 323\u2013344"},{"key":"25109_CR22","first-page":"12","volume":"61","author":"M Nikzamir","year":"2021","unstructured":"Nikzamir M, Akbarzadeh A, Panahi Y (2021) An overview on nanoparticles used in biomedicine and their cytotoxicity. J Drug Deliv Sci Technol 61:12","journal-title":"J Drug Deliv Sci Technol"},{"key":"25109_CR23","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1289\/ehp.7339","volume":"113","author":"G Oberdorster","year":"2005","unstructured":"Oberdorster G, Oberdorster E, Oberdorster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823\u2013839","journal-title":"Environ Health Perspect"},{"key":"25109_CR24","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3109\/08958378.2011.553248","volume":"23","author":"G Oszlanczi","year":"2011","unstructured":"Oszlanczi G, Papp A, Szabo A, Nagymajtenyi L, Sapi A, Konya Z, Paulik E, Vezer T (2011) Nervous system effects in rats on subacute exposure by lead-containing nanoparticles via the airways. Inhal Toxicol 23:173\u2013181","journal-title":"Inhal Toxicol"},{"key":"25109_CR25","first-page":"168","volume":"85","author":"M Peycheva","year":"2022","unstructured":"Peycheva M, Deneva T, Harizanova Z, Zlatareva D (2022) The role of cell adhesion molecules (ICAM-1 and VCAM-1) in acute ischemic stroke. Cesk Slov Neurol Neurochir 85:168\u2013174","journal-title":"Cesk Slov Neurol Neurochir"},{"key":"25109_CR26","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s12872-021-02203-2","volume":"21","author":"A Poursaleh","year":"2021","unstructured":"Poursaleh A, Beigee FS, Esfandiari G, Najafi M (2021) Adhesion of monocytes and endothelial cells isolated from the human aorta suppresses by miRNA-PEI particles. BMC Cardiovasc Disord 21:8","journal-title":"BMC Cardiovasc Disord"},{"key":"25109_CR27","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1080\/14728222.2019.1590336","volume":"23","author":"I Prots","year":"2019","unstructured":"Prots I, Winner B (2019) Th17 cells: a promising therapeutic target for Parkinson\u2019s disease? Expert Opin Ther Targets 23:309\u2013314","journal-title":"Expert Opin Ther Targets"},{"key":"25109_CR28","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.tox.2021.152810","volume":"457","author":"JW Qu","year":"2021","unstructured":"Qu JW, Niu HY, Wang J, Wang Q, Li YJ (2021) Potential mechanism of lead poisoning to the growth and development of ovarian follicle. Toxicology 457:8","journal-title":"Toxicology"},{"key":"25109_CR29","doi-asserted-by":"publisher","first-page":"2504","DOI":"10.1002\/ijc.28927","volume":"136","author":"M Schlesinger","year":"2015","unstructured":"Schlesinger M, Bendas G (2015) Vascular cell adhesion molecule-1 (VCAM-1)-An increasing insight into its role in tumorigenicity and metastasis. Int J Cancer 136:2504\u20132514","journal-title":"Int J Cancer"},{"key":"25109_CR30","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.cis.2022.102640","volume":"303","author":"A Selmani","year":"2022","unstructured":"Selmani A, Kovacevic D, Bohinc K (2022) Nanoparticles: from synthesis to applications and beyond. Adv Colloid Interface Sci 303:12","journal-title":"Adv Colloid Interface Sci"},{"key":"25109_CR31","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ejphar.2021.174216","volume":"905","author":"CK Shen","year":"2021","unstructured":"Shen CK, Huang BR, Yeh WL, Chen CW, Liu YS, Lai SW, Tseng WP, Lu DY, Tsai CF (2021) Regulatory effects of IL-1 beta in the interaction of GBM and tumor-associated monocyte through VCAM-1 and ICAM-1. Eur J Pharmacol 905:12","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"25109_CR32","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1038\/emm.2007.4","volume":"39","author":"HY Song","year":"2007","unstructured":"Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J (2007) Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-\u03baB activation in astrocytes. Experimental & Molecular Medicine 39(1):27\u201337. https:\/\/doi.org\/10.1038\/emm.2007.4","journal-title":"Experimental & Molecular Medicine"},{"key":"25109_CR33","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.bbadis.2021.166170","volume":"1867","author":"MF Troncoso","year":"2021","unstructured":"Troncoso MF, Ortiz-Quintero J, Garrido-Moreno V, Sanhueza-Olivares F, Guerrero-Moncayo A, Chiong M, Castro PF, Garcia L, Gabrielli L, Corbalan R, Garrido-Olivares L, Lavandero S (2021) VCAM-1 as a predictor biomarker in cardiovascular disease. BBA-Mol Basis Dis 1867:13","journal-title":"BBA-Mol Basis Dis"},{"key":"25109_CR34","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1039\/D1EN00957E","volume":"9","author":"J Tulinska","year":"2022","unstructured":"Tulinska J et al (2022) Six-week inhalation of lead oxide nanoparticles in mice affects antioxidant defense, immune response, kidneys, intestine and bones. Environ Sci-Nano 9:751\u2013766","journal-title":"Environ Sci-Nano"},{"key":"25109_CR35","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s10571-004-1380-0","volume":"25","author":"P Turowski","year":"2005","unstructured":"Turowski P, Adamson P, Greenwood J (2005) Pharmacological targeting of ICAM-1 signaling in brain endothelial cells: potential for treating neuroinflammation. Cell Mol Neurobiol 25:153\u2013170","journal-title":"Cell Mol Neurobiol"},{"key":"25109_CR36","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.neubiorev.2021.04.025","volume":"127","author":"ICM Verheggen","year":"2021","unstructured":"Verheggen ICM, Freeze WM, de Jong JJ, Jansen JFA, Postma AA, van Boxtel MP, Verhey FRJ, Backes WH (2021) Application of contrast-enhanced magnetic resonance imaging in the assessment of blood-cerebrospinal fluid barrier integrity. Neurosci Biobehav Rev 127:171\u2013183","journal-title":"Neurosci Biobehav Rev"},{"key":"25109_CR37","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12987-022-00308-0","volume":"19","author":"FR Walter","year":"2022","unstructured":"Walter FR, Harazin A, Toth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczo G, Balla Z, Kui B, Maleth J, Cervenak L, Tubak V, Kittel A, Rakonczay Z, Deli MA (2022) Blood-brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells. Fluids Barriers Cns 19:20","journal-title":"Fluids Barriers Cns"},{"key":"25109_CR38","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.ecoenv.2022.113639","volume":"239","author":"WX Wang","year":"2022","unstructured":"Wang WX, Shi F, Cui JM, Pang SL, Zheng G, Zhang YS (2022) MiR-378a-3p\/ SLC7A11 regulate ferroptosis in nerve injury induced by lead exposure. Ecotoxicol Environ Saf 239:10","journal-title":"Ecotoxicol Environ Saf"},{"key":"25109_CR39","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1155\/2017\/5645324","volume":"2017","author":"WZ Xue","year":"2017","unstructured":"Xue WZ, Yang QQ, Chen YW, Zou RX, Xing D, Xu Y, Liu YS, Wang HL (2017) Kiwifruit alleviates learning and memory deficits induced by Pb through antioxidation and inhibition of microglia activation in vitro and in vivo. Oxid Med Cell Longev 2017:14","journal-title":"Oxid Med Cell Longev"},{"key":"25109_CR40","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s12974-019-1497-1","volume":"16","author":"RC Yang","year":"2019","unstructured":"Yang RC, Qu XY, Xiao SY, Li L, Xu BJ, Fu JY, Lv YJ, Amjad N, Tan C, Kim KS, Chen HC, Wang XR (2019) Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response. J Neuroinflammation 16:15","journal-title":"J Neuroinflammation"},{"key":"25109_CR41","doi-asserted-by":"crossref","unstructured":"Yousef H et al. (2019): Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. Nat Med 25:988-+","DOI":"10.1038\/s41591-019-0440-4"},{"key":"25109_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/4350965","volume":"2016","author":"J Zhang","year":"2016","unstructured":"Zhang J, Wang X, Vikash V, Ye Q, Wu D, Liu Y, Dong W (2016) ROS and ROS-Mediated Cellular Signaling. Oxidative Medicine and Cellular Longevity 2016:1\u201318. https:\/\/doi.org\/10.1155\/2016\/4350965","journal-title":"Oxidative Medicine and Cellular Longevity"},{"key":"25109_CR43","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.1007\/s12011-020-02346-x","volume":"199","author":"LJ Zhang","year":"2021","unstructured":"Zhang LJ, Bo JZ, Chen WW, Li S, Wang Y, Yan LC, Wu L, Zhang YS (2021) The role of Nrf2 on the cognitive dysfunction of high-fat diet mice following lead exposure. Biol Trace Elem Res 199:2247\u20132258","journal-title":"Biol Trace Elem Res"},{"key":"25109_CR44","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.intimp.2017.04.026","volume":"48","author":"Y Zhou","year":"2017","unstructured":"Zhou Y, Wang J, Yang W, Qi X, Lan L, Luo L, Yin Z (2017) Bergapten prevents lipopolysaccharide-induced inflammation in RAW264.7 cells through suppressing JAK\/STAT activation and ROS production and increases the survival rate of mice after LPS challenge. Int Immunopharmacol 48:159\u2013168","journal-title":"Int Immunopharmacol"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-022-25109-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-022-25109-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-022-25109-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T02:16:51Z","timestamp":1680488211000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-022-25109-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":44,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["25109"],"URL":"https:\/\/doi.org\/10.1007\/s11356-022-25109-8","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-1956358\/v1","asserted-by":"object"}]},"ISSN":["1614-7499"],"issn-type":[{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,6]]},"assertion":[{"value":"25 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No involved.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"No involved.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All authors have read and approved the manuscript and have accorded consent for publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}