{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:43:55Z","timestamp":1791315835198,"version":"4.3.1"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"43","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"DOI":"10.1007\/s11356-024-34868-5","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T03:31:21Z","timestamp":1725593481000},"page":"55610-55623","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Toxic effects of dibutyl phthalate on testes of adult zebrafish: evaluation of oxidative stress parameters and histopathology"],"prefix":"10.1007","volume":"31","author":[{"given":"Swati S.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8488-0161","authenticated-orcid":false,"given":"Bhavesh J.","family":"Trangadia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urvesh D.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajkumar S.","family":"Delvadiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulkadir A.","family":"Makwana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir H.","family":"Raval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval T.","family":"Fefar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"34868_CR1","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.jenvman.2012.05.014","volume":"109","author":"MM Abdel daiem","year":"2012","unstructured":"Abdel daiem MM, Rivera-Utrilla J, Ocampo-Perez R, Mendez-Diaz JD, Sanchez-Polo M (2012) Environmental impact of phthalic acid esters and their removal from water and sediments by different technologies - a review. J Environ Manag 109:164\u2013178. https:\/\/doi.org\/10.1016\/j.jenvman.2012.05.014","journal-title":"J Environ Manag"},{"issue":"4","key":"34868_CR2","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/s0015-0282(02)04948-8","volume":"79","author":"A Agarwal","year":"2003","unstructured":"Agarwal A, Saleh RA, Bedaiwy MA (2003) Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 79(4):829\u2013843. https:\/\/doi.org\/10.1016\/s0015-0282(02)04948-8","journal-title":"Fertil Steril"},{"issue":"3","key":"34868_CR3","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/s0378-4274(02)00418-6","volume":"138","author":"RK Al-Thani","year":"2003","unstructured":"Al-Thani RK, Al-Thani AS, Elbetieha A, Darmani H (2003) Assessment of reproductive and fertility effects of amitraz pesticide in male mice. Toxicol Lett 138(3):253\u2013260. https:\/\/doi.org\/10.1016\/s0378-4274(02)00418-6","journal-title":"Toxicol Lett"},{"issue":"8","key":"34868_CR4","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1177\/0748233714566877","volume":"32","author":"HA Aly","year":"2016","unstructured":"Aly HA, Hassan MH, El-Beshbishy HA, Alahdal AM, Osman AM (2016) Dibutyl phthalate induces oxidative stress and impairs spermatogenesis in adult rats. Toxicol Ind Health 32(8):1467\u20131477. https:\/\/doi.org\/10.1177\/0748233714566877","journal-title":"Toxicol Ind Health"},{"issue":"2","key":"34868_CR5","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1093\/toxsci\/kfg087","volume":"73","author":"NJ Barlow","year":"2003","unstructured":"Barlow NJ, Phillips SL, Wallace DG, Sar M, Gaido KW, Foster PM (2003) Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate. Toxicol Sci: An Off J Soc Toxicol 73(2):431\u2013441. https:\/\/doi.org\/10.1093\/toxsci\/kfg087","journal-title":"Toxicol Sci: An Off J Soc Toxicol"},{"key":"34868_CR6","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.biochi.2020.05.002","volume":"175","author":"H Batista-Silva","year":"2020","unstructured":"Batista-Silva H, Dambr\u00f3s BF, Rodrigues K, Cesconetto PA, Zamoner A, de Sousa Moura KR, Gomes Castro AJ, Van Der Kraak G, Mena Barreto Silva FR (2020) Acute exposure to bis(2-ethylhexyl)phthalate disrupts calcium homeostasis, energy metabolism and induces oxidative stress in the testis of Danio rerio. Biochimie 175:23\u201333. https:\/\/doi.org\/10.1016\/j.biochi.2020.05.002","journal-title":"Biochimie"},{"key":"34868_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.cbpc.2018.02.003","volume":"206\u2013207","author":"FEA Bautista","year":"2018","unstructured":"Bautista FEA, Varela Junior AS, Corcini CD, Acosta IB, Caldas SS, Primel EG, Zanette J (2018) The herbicide atrazine affects sperm quality and the expression of antioxidant and spermatogenesis genes in zebrafish testes. Comp Biochem Physiol C Toxicol Pharmacol 206\u2013207:17\u201322. https:\/\/doi.org\/10.1016\/j.cbpc.2018.02.003","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"issue":"1","key":"34868_CR8","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","volume":"195","author":"RF Beers Jr","year":"1952","unstructured":"Beers RF Jr, Sizer IW (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 195(1):133\u2013140","journal-title":"J Biol Chem"},{"issue":"1","key":"34868_CR9","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.reprotox.2003.10.011","volume":"18","author":"J Borch","year":"2004","unstructured":"Borch J, Ladefoged O, Hass U, Vinggaard AM (2004) Steroidogenesis in fetal male rats is reduced by DEHP and DINP, but endocrine effects of DEHP are not modulated by DEHA in fetal, prepubertal, and adult male rats. Reprod Toxicol 18(1):53\u201361. https:\/\/doi.org\/10.1016\/j.reprotox.2003.10.011","journal-title":"Reprod Toxicol"},{"issue":"3","key":"34868_CR10","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/etc.2803","volume":"34","author":"P Chen","year":"2015","unstructured":"Chen P, Li S, Liu L, Xu N (2015) Long-term effects of binary mixtures of 17\u03b1-ethinylestradiol and dibutyl phthalate in a partial life-cycle test with zebrafish (Danio rerio). Environ Toxicol Chem 34(3):518\u2013526. https:\/\/doi.org\/10.1002\/etc.2803","journal-title":"Environ Toxicol Chem"},{"key":"34868_CR11","doi-asserted-by":"publisher","first-page":"127238","DOI":"10.1016\/j.chemosphere.2020.127238","volume":"258","author":"H Chen","year":"2020","unstructured":"Chen H, Chen K, Qiu X, Xu H, Mao G, Zhao T, Feng W, Okeke ES, Wu X, Yang L (2020) The reproductive toxicity and potential mechanisms of combined exposure to dibutyl phthalate and diisobutyl phthalate in male zebrafish (Danio rerio). Chemosphere 258:127238. https:\/\/doi.org\/10.1016\/j.chemosphere.2020.127238","journal-title":"Chemosphere"},{"issue":"1","key":"34868_CR12","doi-asserted-by":"publisher","first-page":"15","DOI":"10.13075\/ijomeh.1896.01658","volume":"34","author":"E Czubacka","year":"2021","unstructured":"Czubacka E, Czerczak S, Kupczewska-Dobecka MM (2021) Overview of current evidence on the reproductive toxicity of dibutyl phthalate. Int J Occup Med Environ Health 34(1):15\u201337. https:\/\/doi.org\/10.13075\/ijomeh.1896.01658","journal-title":"Int J Occup Med Environ Health"},{"key":"34868_CR13","doi-asserted-by":"publisher","first-page":"006","DOI":"10.4172\/2155-9929.S2-006","volume":"S2","author":"M De Moraes","year":"2012","unstructured":"De Moraes M, Monteiro Maia CAD, de Almeida Freitas R, Galvao HC (2012) Cell proliferation markers in oral squamous cell carcinoma. J Mol Biomark Diagn S2:006. https:\/\/doi.org\/10.4172\/2155-9929.S2-006","journal-title":"J Mol Biomark Diagn"},{"issue":"6","key":"34868_CR14","doi-asserted-by":"publisher","first-page":"508","DOI":"10.5937\/arhfarm71-34438","volume":"71","author":"P Erkekoglu","year":"2021","unstructured":"Erkekoglu P, Ozyurt AB, Yirun A, Cakir DA (2021) Testicular dysgenesis syndrome and phthalate exposure: a review of the literature. Arch Pharm 71(6):508\u2013543. https:\/\/doi.org\/10.5937\/arhfarm71-34438","journal-title":"Arch Pharm"},{"issue":"6","key":"34868_CR15","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1016\/s0043-1354(01)00367-0","volume":"36","author":"H Fromme","year":"2002","unstructured":"Fromme H, Kuchler T, Otto T, Pilz K, Muller J, Wenzel A (2002) Occurrence of phthalates and bisphenol A and F in the environment. Water Res 36(6):1429\u20131438. https:\/\/doi.org\/10.1016\/s0043-1354(01)00367-0","journal-title":"Water Res"},{"issue":"16","key":"34868_CR16","doi-asserted-by":"publisher","first-page":"5655","DOI":"10.3390\/ijerph17165655","volume":"17","author":"A Giuliani","year":"2020","unstructured":"Giuliani A, Zuccarini M, Cichelli A, Khan H, Reale M (2020) Critical review on the presence of phthalates in food and evidence of their biological impact. Int J Environ Res Public Health 17(16):5655. https:\/\/doi.org\/10.3390\/ijerph17165655","journal-title":"Int J Environ Res Public Health"},{"key":"34868_CR17","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1289\/ehp.8665229","volume":"65","author":"TJ Gray","year":"1986","unstructured":"Gray TJ, Gangolli SD (1986) Aspects of the testicular toxicity of phthalate esters. Environ Health Perspect 65:229\u2013235. https:\/\/doi.org\/10.1289\/ehp.8665229","journal-title":"Environ Health Perspect"},{"issue":"17","key":"34868_CR18","doi-asserted-by":"publisher","first-page":"3693","DOI":"10.1016\/j.watres.2004.06.012","volume":"38","author":"O Horn","year":"2004","unstructured":"Horn O, Nalli S, Cooper D, Nicell J (2004) Plasticizer metabolites in the environment. Water Res 38(17):3693\u20133698. https:\/\/doi.org\/10.1016\/j.watres.2004.06.012","journal-title":"Water Res"},{"key":"34868_CR19","doi-asserted-by":"publisher","first-page":"115836","DOI":"10.1016\/j.envpol.2020.115836","volume":"274","author":"MM Hossain","year":"2021","unstructured":"Hossain MM, Huang H, Yuan Y, Wan T, Jiang C, Dai Z, Xiong S, Cao M, Tu S (2021) Silicone stressed response of crayfish (Procambarus clarkii) in antioxidant enzyme activity and related gene expression. Environ Pollut 274:115836. https:\/\/doi.org\/10.1016\/j.envpol.2020.115836","journal-title":"Environ Pollut"},{"issue":"12","key":"34868_CR20","doi-asserted-by":"publisher","first-page":"1694","DOI":"10.1002\/jat.4030","volume":"40","author":"J Hu","year":"2020","unstructured":"Hu J, Jiang K, Tang X, Liu H, Zhang H, Yang X, Nie X, Luo H (2020) Chronic exposure to di-n-butyl phthalate causes reproductive toxicity in zebrafish. J Appl Toxicol: JAT 40(12):1694\u20131703. https:\/\/doi.org\/10.1002\/jat.4030","journal-title":"J Appl Toxicol: JAT"},{"issue":"7","key":"34868_CR21","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1017\/S1751731117003111","volume":"12","author":"ML Jaramillo","year":"2018","unstructured":"Jaramillo ML, Pereira AG, Davico CE, Nezzi L, Ammar D, Muller YMR, Nazari EM (2018) Evaluation of reference genes for reverse transcription-quantitative PCR assays in organs of zebrafish exposed to glyphosate-based herbicide, Roundup. Animal: An Int J Anim Biosci 12(7):1424\u20131434. https:\/\/doi.org\/10.1017\/S1751731117003111","journal-title":"Animal: An Int J Anim Biosci"},{"key":"34868_CR22","doi-asserted-by":"publisher","first-page":"127749","DOI":"10.1016\/j.jhazmat.2021.127749","volume":"424","author":"N Jiang","year":"2022","unstructured":"Jiang N, Song P, Li X, Zhu L, Wang J, Yin X, Wang J (2022) Dibutyl phthalate induced oxidative stress and genotoxicity on adult zebrafish (Danio rerio) brain. J Hazard Mater 424:127749. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.127749","journal-title":"J Hazard Mater"},{"key":"34868_CR23","doi-asserted-by":"publisher","first-page":"113517","DOI":"10.1016\/j.envpol.2019.113517","volume":"257","author":"Y Jiao","year":"2020","unstructured":"Jiao Y, Tao Y, Yang Y, Diogene T, Yu H, He Z, Han W, Chen Z, Wu P, Zhang Y (2020) Monobutyl phthalate (MBP) can dysregulate the antioxidant system and induce apoptosis of zebrafish liver. Environ Pollut 257:113517. https:\/\/doi.org\/10.1016\/j.envpol.2019.113517","journal-title":"Environ Pollut"},{"issue":"5","key":"34868_CR24","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.fertnstert.2007.05.029","volume":"89","author":"SH Kao","year":"2008","unstructured":"Kao SH, Chao HT, Chen HW, Hwang TIS, Liao TL, Wei YH (2008) Increase of oxidative stress in human sperm with lower motility. Fertil Steril 89(5):1183\u20131190. https:\/\/doi.org\/10.1016\/j.fertnstert.2007.05.029","journal-title":"Fertil Steril"},{"issue":"5","key":"34868_CR25","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/s0890-6238(02)00032-1","volume":"16","author":"R Kavlock","year":"2002","unstructured":"Kavlock R, Boekelheide K, Chapin R, Cunningham M, Faustman E, Foster P, Golub M, Henderson R, Hinberg I, Little R, Seed J, Shea K, Tabacova S, Tyl R, Williams P, Zacharewski T (2002) NTP center for the evaluation of risks to human reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di(2-ethylhexyl) phthalate. Reprod Toxicol 16(5):529\u2013653. https:\/\/doi.org\/10.1016\/s0890-6238(02)00032-1","journal-title":"Reprod Toxicol"},{"key":"34868_CR26","doi-asserted-by":"publisher","first-page":"105503","DOI":"10.1016\/j.aquatox.2020.105503","volume":"224","author":"XR Lan","year":"2020","unstructured":"Lan XR, Li YW, Chen QL, Shen YJ, Liu ZH (2020) Tributyltin impaired spermatogenesis and reproductive behavior in male zebrafish. Aquat Toxicol 224:105503. https:\/\/doi.org\/10.1016\/j.aquatox.2020.105503","journal-title":"Aquat Toxicol"},{"issue":"3","key":"34868_CR27","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1093\/molehr\/6.3.226","volume":"6","author":"A Lenzi","year":"2000","unstructured":"Lenzi A, Gandini L, Maresca V, Rago R, Sgro P, Dondero F, Picardo M (2000) Fatty acid composition of spermatozoa and immature germ cells. Mol Hum Reprod 6(3):226\u2013231. https:\/\/doi.org\/10.1093\/molehr\/6.3.226","journal-title":"Mol Hum Reprod"},{"issue":"12","key":"34868_CR28","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.1016\/j.jpedsurg.2015.08.046","volume":"50","author":"N Li","year":"2015","unstructured":"Li N, Chen X, Zhou X, Zhang W, Yuan J, Feng J (2015) The mechanism underlying dibutyl phthalate induced shortened anogenital distance and hypospadias in rats. J Pediatr Surg 50(12):2078\u20132083. https:\/\/doi.org\/10.1016\/j.jpedsurg.2015.08.046","journal-title":"J Pediatr Surg"},{"issue":"4","key":"34868_CR29","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method. Methods 25(4):402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods"},{"key":"34868_CR30","unstructured":"Luna LG (1968) Routine staining procedures: hematoxylin and eosin stains. In: Manual of histologic staining methods of the Armed Forces Institute of Pathology (3rd ed.). McGraw-Hill, New York"},{"issue":"9","key":"34868_CR31","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1093\/clinchem\/47.9.1725","volume":"47","author":"J Lykkesfeldt","year":"2001","unstructured":"Lykkesfeldt J (2001) Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry. Clin Chem 47(9):1725\u20131727. https:\/\/doi.org\/10.1093\/clinchem\/47.9.1725","journal-title":"Clin Chem"},{"issue":"3","key":"34868_CR32","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","volume":"47","author":"S Marklund","year":"1974","unstructured":"Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47(3):469\u2013474. https:\/\/doi.org\/10.1111\/j.1432-1033.1974.tb03714.x","journal-title":"Eur J Biochem"},{"key":"34868_CR33","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s11160-005-7846-4","volume":"15","author":"RM Martinez-Alvarez","year":"2005","unstructured":"Martinez-Alvarez RM, Morales AE, Sanz A (2005) Antioxidant defenses in fish: biotic and abiotic factors. Rev Fish Biol Fish 15:75\u201388. https:\/\/doi.org\/10.1007\/s11160-005-7846-4","journal-title":"Rev Fish Biol Fish"},{"issue":"2","key":"34868_CR34","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1080\/01652176.2005.9695186","volume":"27","author":"S Mukaratirwa","year":"2005","unstructured":"Mukaratirwa S (2005) Prognostic and predictive markers in canine tumours: rationale and relevance- a review. Vet Q 27(2):52\u201364. https:\/\/doi.org\/10.1080\/01652176.2005.9695186","journal-title":"Vet Q"},{"issue":"1\u20132","key":"34868_CR35","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/s1383-5718(01)00308-4","volume":"513","author":"K Narayana","year":"2002","unstructured":"Narayana K, D\u2019Souza UJ, Seetharama Rao KP (2002) Ribavirin-induced sperm shape abnormalities in Wistar rat. Mutat Res 513(1\u20132):193\u2013196. https:\/\/doi.org\/10.1016\/s1383-5718(01)00308-4","journal-title":"Mutat Res"},{"key":"34868_CR36","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.ecoenv.2018.10.040","volume":"168","author":"H Ni","year":"2019","unstructured":"Ni H, Peng L, Gao X, Ji H, Ma J, Li Y, Jiang S (2019) Effects of maduramicin on adult zebrafish (Danio rerio): acute toxicity, tissue damage and oxidative stress. Ecotoxicol Environ Saf 168:249\u2013259. https:\/\/doi.org\/10.1016\/j.ecoenv.2018.10.040","journal-title":"Ecotoxicol Environ Saf"},{"key":"34868_CR37","doi-asserted-by":"publisher","first-page":"e00816","DOI":"10.1016\/j.sciaf.2021.e00816","volume":"12","author":"GA Ogunwole","year":"2021","unstructured":"Ogunwole GA, Abiya SE, Amaeze NH, Eze CT (2021) Antioxidant markers in gills, liver and muscle tissue of the African Sharptooth Catfish (Clarias gariepinus) exposed to subchronic levels of ibuprofen and dibutyl phthalate. Sci Afr 12:e00816. https:\/\/doi.org\/10.1016\/j.sciaf.2021.e00816","journal-title":"Sci Afr"},{"issue":"6","key":"34868_CR38","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1007\/s11356-012-0960-7","volume":"19","author":"H Paskerova","year":"2012","unstructured":"Paskerova H, Hilscherova K, Blaha L (2012) Oxidative stress and detoxification biomarker responses in aquatic freshwater vertebrates exposed to microcystins and cyanobacterial biomass. Environ Sci Pollut Res Int 19(6):2024\u20132037. https:\/\/doi.org\/10.1007\/s11356-012-0960-7","journal-title":"Environ Sci Pollut Res Int"},{"issue":"6","key":"34868_CR39","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1210\/edrv.22.6.0446","volume":"22","author":"TM Plant","year":"2001","unstructured":"Plant TM, Marshall GR (2001) The functional significance of FSH in spermatogenesis and the control of its secretion in male primates. Endocr Rev 22(6):764\u2013786. https:\/\/doi.org\/10.1210\/edrv.22.6.0446","journal-title":"Endocr Rev"},{"key":"34868_CR40","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1016\/j.toxrep.2020.06.008","volume":"7","author":"MJ Radha","year":"2020","unstructured":"Radha MJ, Mahaboob BP (2020) Hepatotoxic evaluation of Di-n-butyl phthalate in Wistar rats upon sub-chronic exposure: a multigenerational assessment. Toxicol Rep 7:772\u2013778. https:\/\/doi.org\/10.1016\/j.toxrep.2020.06.008","journal-title":"Toxicol Rep"},{"issue":"1","key":"34868_CR41","doi-asserted-by":"publisher","first-page":"19","DOI":"10.5958\/0973-970X.2018.00004.4","volume":"42","author":"SH Raval","year":"2018","unstructured":"Raval SH, Joshi DV, Parmar RS, Patel BJ, Patel JG, Patel VB, Ghodasara DJ, Chaudhary PS, Kalaria VA, Charavala AH (2018) Histopathological classification and immunohistochemical characterization of canine mammary tumours. Indian J Vet Pathol 42(1):19\u201327. https:\/\/doi.org\/10.5958\/0973-970X.2018.00004.4","journal-title":"Indian J Vet Pathol"},{"key":"34868_CR42","volume-title":"Molecular cloning: a laboratory","author":"L Sambrook","year":"2001","unstructured":"Sambrook L, Russell RW (2001) Molecular cloning: a laboratory, 3rd edn. Cold Spring Laboratory Press, Cold Spring Harbor","edition":"3"},{"key":"34868_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ecoenv.2014.05.012","volume":"107","author":"S Sarkar","year":"2014","unstructured":"Sarkar S, Mukherjee S, Chattopadhyay A, Bhattacharya S (2014) Low dose of arsenic trioxide triggers oxidative stress in zebrafish brain: expression of antioxidant genes. Ecotoxicol Environ Saf 107:1\u20138. https:\/\/doi.org\/10.1016\/j.ecoenv.2014.05.012","journal-title":"Ecotoxicol Environ Saf"},{"issue":"1","key":"34868_CR44","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1111\/j.1365-2605.2005.00567.x","volume":"29","author":"T Schettler","year":"2006","unstructured":"Schettler T (2006) Human exposure to phthalates via consumer products. Int J Androl 29(1):134\u2013185. https:\/\/doi.org\/10.1111\/j.1365-2605.2005.00567.x","journal-title":"Int J Androl"},{"issue":"10","key":"34868_CR45","doi-asserted-by":"publisher","first-page":"5280","DOI":"10.1210\/en.2008-0413","volume":"149","author":"HM Scott","year":"2008","unstructured":"Scott HM, Hutchison GR, Jobling MS, McKinnell C, Drake AJ, Sharpe RM (2008) Relationship between androgen action in the \u201cmale programming window\u201d, fetal sertoli cell number, and adult testis size in the rat. Endocrinology 149(10):5280\u20135287. https:\/\/doi.org\/10.1210\/en.2008-0413","journal-title":"Endocrinology"},{"key":"34868_CR46","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.chemosphere.2018.09.104","volume":"214","author":"P Shaw","year":"2019","unstructured":"Shaw P, Mondal P, Bandyopadhyay A, Chattopadhyay A (2019) Environmentally relevant concentration of chromium activates nrf2 and alters transcription of related xme genes in liver of zebrafish. Chemosphere 214:35\u201346. https:\/\/doi.org\/10.1016\/j.chemosphere.2018.09.104","journal-title":"Chemosphere"},{"issue":"6","key":"34868_CR47","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.3969\/j.issn.1001-0505.2010.06.040","volume":"40","author":"Y Shen","year":"2010","unstructured":"Shen Y, Xu Q, Yin X, Wang M, Zhang N, Wu S, Zang Z, Gu Z, Wang H (2010) Determination and distribution features of phthalate esters in Xuanwu lake. J Southeast Univ (Natural Science Edition) 40(6):1337\u20131341. https:\/\/doi.org\/10.3969\/j.issn.1001-0505.2010.06.040","journal-title":"J Southeast Univ (Natural Science Edition)"},{"key":"34868_CR48","doi-asserted-by":"publisher","first-page":"e6584","DOI":"10.7717\/peerj.6584","volume":"7","author":"C Shen","year":"2019","unstructured":"Shen C, Wei J, Wang T, Wang Y (2019) Acute toxicity and responses of antioxidant systems to dibutyl phthalate in neonate and adult Daphnia magna. Peer J 7:e6584. https:\/\/doi.org\/10.7717\/peerj.6584","journal-title":"Peer J"},{"key":"34868_CR49","doi-asserted-by":"publisher","first-page":"128027","DOI":"10.1016\/j.jhazmat.2021.128027","volume":"425","author":"P Song","year":"2022","unstructured":"Song P, Jiang N, Zhang K, Li X, Li N, Zhang Y, Wang Q, Wang J (2022) Ecotoxicological evaluation of zebrafish liver (Danio rerio) induced by dibutyl phthalate. J Hazard Mater 425:128027. https:\/\/doi.org\/10.1016\/j.jhazmat.2021.128027","journal-title":"J Hazard Mater"},{"issue":"1\u20134","key":"34868_CR50","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s10661-009-1182-4","volume":"169","author":"A Srivastava","year":"2010","unstructured":"Srivastava A, Sharma VP, Tripathi R, Kumar R, Patel DK, Mathur PK (2010) Occurrence of phthalic acid esters in Gomti River Sediment, India. Environ Monit Assess 169(1\u20134):397\u2013406. https:\/\/doi.org\/10.1007\/s10661-009-1182-4","journal-title":"Environ Monit Assess"},{"issue":"3","key":"34868_CR51","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/10454438.2020.1742268","volume":"33","author":"M Sruthi","year":"2021","unstructured":"Sruthi M, Raibeemol KP, Chitra KC (2021) Involvement of dibutyl phthalate on male reproductive toxicity in the freshwater fish Pseudetroplus maculatus (Bloch, 1795). J Appl Aquac 33(3):221\u2013245. https:\/\/doi.org\/10.1080\/10454438.2020.1742268","journal-title":"J Appl Aquac"},{"key":"34868_CR52","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-4440-7_24","volume-title":"Hormonal regulation of spermatogenesis. Current topics in Molecular Endocrinology","author":"E Steinberger","year":"1975","unstructured":"Steinberger E (1975) Hormonal regulation of the seminiferous tubule function. In: French FS, Hansson V, Ritzen EM, Nayfeh SN (eds) Hormonal regulation of spermatogenesis. Current topics in Molecular Endocrinology, vol 2. Springer, Boston. https:\/\/doi.org\/10.1007\/978-1-4613-4440-7_24"},{"issue":"5","key":"34868_CR53","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1089\/zeb.2016.1259","volume":"13","author":"RR Velasques","year":"2016","unstructured":"Velasques RR, Sandrini JZ, da Rosa CE (2016) Roundup in zebrafish: effects on oxidative status and gene expression. Zebrafish 13(5):432\u2013441. https:\/\/doi.org\/10.1089\/zeb.2016.1259","journal-title":"Zebrafish"},{"issue":"4","key":"34868_CR54","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s00244-017-0451-4","volume":"74","author":"G Wang","year":"2018","unstructured":"Wang G, Wang J, Zhu L, Wang J, Li H, Zhang Y, Liu W, Gao J (2018) Oxidative damage and genetic toxicity induced by DBP in earthworms (Eisenia fetida). Arch Environ Contam Toxicol 74(4):527\u2013538. https:\/\/doi.org\/10.1007\/s00244-017-0451-4","journal-title":"Arch Environ Contam Toxicol"},{"issue":"5","key":"34868_CR55","doi-asserted-by":"publisher","first-page":"052052","DOI":"10.1088\/1755-1315\/227\/5\/052052","volume":"227","author":"T Wang","year":"2019","unstructured":"Wang T, Wei J, Wang L, Lu Y, Zhang Q, Wang Y (2019) Effect of dibutyl phthalate on antioxidant parameters and related gene expression in Daphnia magna. IOP Conf Ser: Earth Environ Sci 227(5):052052. https:\/\/doi.org\/10.1088\/1755-1315\/227\/5\/052052","journal-title":"IOP Conf Ser: Earth Environ Sci"},{"issue":"1","key":"34868_CR56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0165-1110(83)90014-3","volume":"115","author":"AJ Wyrobek","year":"1983","unstructured":"Wyrobek AJ, Gordon LA, Burkhart JG, Francis MW, Kapp RW Jr, Letz G, Malling HV, Topham JC, Whorton MD (1983) An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res 115(1):1\u201372. https:\/\/doi.org\/10.1016\/0165-1110(83)90014-3","journal-title":"Mutat Res"},{"key":"34868_CR57","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.ecoenv.2013.03.038","volume":"93","author":"H Xu","year":"2013","unstructured":"Xu H, Shao X, Zhang Z, Zou Y, Wu X, Yang L (2013) Oxidative stress and immune related gene expression following exposure to di-n-butyl phthalate and diethyl phthalate in zebrafish embryos. Ecotoxicol Environ Saf 93:39\u201344. https:\/\/doi.org\/10.1016\/j.ecoenv.2013.03.038","journal-title":"Ecotoxicol Environ Saf"},{"key":"34868_CR58","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.ecoenv.2014.05.001","volume":"107","author":"N Xu","year":"2014","unstructured":"Xu N, Chen P, Liu L, Zeng Y, Zhou H, Li S (2014) Effects of combined exposure to 17\u03b1-ethynylestradiol and dibutyl phthalate on the growth and reproduction of adult male zebrafish (Danio rerio). Ecotoxicol Environ Saf 107:61\u201370. https:\/\/doi.org\/10.1016\/j.ecoenv.2014.05.001","journal-title":"Ecotoxicol Environ Saf"},{"issue":"24","key":"34868_CR59","doi-asserted-by":"publisher","first-page":"10941","DOI":"10.1128\/MCB.24.24.10941-10953.2004","volume":"24","author":"DD Zhang","year":"2004","unstructured":"Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 24(24):10941\u201310953. https:\/\/doi.org\/10.1128\/MCB.24.24.10941-10953.2004","journal-title":"Mol Cell Biol"},{"issue":"1","key":"34868_CR60","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3967\/0895-3988.2013.01.008","volume":"26","author":"WZ Zhang","year":"2013","unstructured":"Zhang WZ, Yong L, Jia XD, Li N, Fan YX (2013) Combined subchronic toxicity of bisphenol A and dibutyl phthalate on male rats. Biomed Environ Sci 26(1):63\u201369. https:\/\/doi.org\/10.3967\/0895-3988.2013.01.008","journal-title":"Biomed Environ Sci"},{"key":"34868_CR61","doi-asserted-by":"publisher","first-page":"241","DOI":"10.4028\/www.scientific.net\/AMM.448-453.241","volume":"448","author":"J Zhang","year":"2014","unstructured":"Zhang J, Li H, Yu JH (2014) Oxidative stress effect on testicular germ cells and liver cells in mice induced by dibutyl phthalate. Appl Mech Mater 448:241\u2013244. https:\/\/doi.org\/10.4028\/www.scientific.net\/AMM.448-453.241","journal-title":"Appl Mech Mater"},{"key":"34868_CR62","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.envpol.2018.04.056","volume":"240","author":"ZM Zhang","year":"2018","unstructured":"Zhang ZM, Zhang HH, Zou YW, Yang GP (2018) Distribution and ecotoxicological state of phthalate esters in the sea-surface microlayer, seawater and sediment of the Bohai Sea and the Yellow Sea. Environ Pollut 240:235\u2013247. https:\/\/doi.org\/10.1016\/j.envpol.2018.04.056","journal-title":"Environ Pollut"},{"key":"34868_CR63","doi-asserted-by":"publisher","first-page":"113666","DOI":"10.1016\/j.envpol.2019.113666","volume":"258","author":"C Zhang","year":"2020","unstructured":"Zhang C, Zhou T, Du Z, Juhasz A, Zhu L, Wang J, Wang J, Li B (2020) Applying fungicide on earthworms: biochemical effects of Eisenia fetida exposed to fluoxastrobin in three natural soils. Environ Pollut 258:113666. https:\/\/doi.org\/10.1016\/j.envpol.2019.113666","journal-title":"Environ Pollut"},{"issue":"6","key":"34868_CR64","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3109\/19396368.2010.509902","volume":"56","author":"D Zhou","year":"2010","unstructured":"Zhou D, Wang H, Zhang J, Gao X, Zhao W, Zheng Y (2010) Di-n-butyl phthalate (DBP) exposure induces oxidative damage in testes of adult rats. Syst Biol Reprod Med 56(6):413\u2013419. https:\/\/doi.org\/10.3109\/19396368.2010.509902","journal-title":"Syst Biol Reprod Med"},{"key":"34868_CR65","doi-asserted-by":"publisher","first-page":"133793","DOI":"10.1016\/j.scitotenv.2019.133793","volume":"695","author":"F Zhu","year":"2019","unstructured":"Zhu F, Zhang H, Qiu M, Wu N, Zeng K, Du D (2019) Dual-label time-resolved fluoroimmunoassay as an advantageous approach for investigation of diethyl phthalate & dibutyl phthalate in surface water. Sci Total Environ 695:133793. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.133793","journal-title":"Sci Total Environ"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-024-34868-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-024-34868-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-024-34868-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T07:38:56Z","timestamp":1726817936000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-024-34868-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,6]]},"references-count":65,"journal-issue":{"issue":"43","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["34868"],"URL":"https:\/\/doi.org\/10.1007\/s11356-024-34868-5","relation":{},"ISSN":["1614-7499"],"issn-type":[{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,6]]},"assertion":[{"value":"3 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This manuscript is a part of M.V.Sc. thesis submitted by the first author to Kamdhenu University, Gandhinagar, Gujarat, India. This experimental protocol and procedures were approved by the Institutional Animal Ethics Committee, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat, India, vide protocol no: KU-JVC-IAEC-SA-93\u201322.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}