{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T14:30:09Z","timestamp":1794580209010,"version":"4.9.1"},"reference-count":122,"publisher":"Springer Science and Business Media LLC","issue":"35","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Sci Pollut Res"],"DOI":"10.1007\/s11356-025-36795-5","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:44:00Z","timestamp":1756295040000},"page":"20799-20824","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pharmaceuticals, personal care products, and illicit drugs in the aquatic environment and occurrence of the antimicrobial resistance in Brazil: a systematic review"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0759-111X","authenticated-orcid":false,"given":"Juliana Lemos Dal","family":"Pizzol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tain\u00e1 Larissa","family":"Lubschinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduarda Talita Bramorski","family":"Mohr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izadora Borgmann","family":"Frizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabel Galhardo","family":"Demarchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussara Kasuko","family":"Palmeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8177-4195","authenticated-orcid":false,"given":"Tha\u00eds Cristine Marques","family":"Sincero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"key":"36795_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2020.105776","volume":"31","author":"R \u00c1lvarez-Ruiz","year":"2020","unstructured":"\u00c1lvarez-Ruiz R, Pic\u00f3 Y, Alfarhan AH, El-Sheikh MA, Alshahrani HO, Barcel\u00f3 D (2020) Dataset of pesticides, pharmaceuticals and personal care products occurrence in wetlands of Saudi Arabia. Data Brief 31. https:\/\/doi.org\/10.1016\/j.dib.2020.105776","journal-title":"Data Brief"},{"key":"36795_CR2","unstructured":"Am\u00e9rico J H P, Isique W D, Ortega D J P, S\u00e1nchez Ortiz I A, Torres N H, Ferreira L F R, Manoel L O & Carvalho S L. (2015). Monitoreo del anti-inflamatorio piroxicam y del anti-hipertensivo atenolol en un arroyo urbano en Tr\u00eas Lagoas, Brasil. Interciencia, 40(10), 670\u2013673. Available at: https:\/\/www.redalyc.org\/articulo.oa?id=33941643004"},{"key":"36795_CR3","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.emcon.2020.02.004","volume":"6","author":"JE Anekwe","year":"2020","unstructured":"Anekwe JE, Oluseyi T, Drage DS, Harrad S, Abdallah MAE (2020) Occurrence, seasonal variation and human exposure to pharmaceuticals and personal care products in surface water, groundwater and drinking water in Lagos State, Nigeria. Emerg Contam 6:124\u2013132. https:\/\/doi.org\/10.1016\/j.emcon.2020.02.004","journal-title":"Emerg Contam"},{"key":"36795_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.marpolbul.2020.111014","volume":"153","author":"AK Anim","year":"2020","unstructured":"Anim AK, Thompson K, Duodu GO, Tscharke B, Birch G, Goonetilleke A, Ayoko GA, Mueller JF (2020) Pharmaceuticals, personal care products, food additive and pesticides in surface waters from three Australian east coast estuaries (Sydney, Yarra and Brisbane). Mar Pollut Bull 153. https:\/\/doi.org\/10.1016\/j.marpolbul.2020.111014","journal-title":"Mar Pollut Bull"},{"key":"36795_CR5","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.chemosphere.2017.01.101","volume":"174","author":"E Archer","year":"2017","unstructured":"Archer E, Petrie B, Kasprzyk-Hordern B, Wolfaardt GM (2017) The fate of pharmaceuticals and personal care products (PPCPs), endocrine disrupting contaminants (EDCs), metabolites and illicit drugs in a WWTW and environmental waters. Chemosphere 174:437\u2013446. https:\/\/doi.org\/10.1016\/j.chemosphere.2017.01.101","journal-title":"Chemosphere"},{"key":"36795_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.139781","volume":"738","author":"JB Arsand","year":"2020","unstructured":"Arsand JB, Hoff RB, Jank L, Bussamara R, Dallegrave A, Bento FM, Kmetzsch L, Fal\u00e7\u00e3o DA, Peralba MCR, Gomes AA, Pizzolato TM (2020) Presence of antibiotic resistance genes and its association with antibiotic occurrence in Dil\u00favio River in southern Brazil. Sci Total Environ 738. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.139781","journal-title":"Sci Total Environ"},{"key":"36795_CR7","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.3389\/fmicb.2019.02892","volume":"10","author":"F Baquero","year":"2019","unstructured":"Baquero F, Coque TM, Mart\u00ednez JL, Aracil-Gisbert S, Lanza VF (2019) Gene transmission in the One Health microbiosphere and the channels of antimicrobial resistance. Front Microbiol 10:2892. https:\/\/doi.org\/10.3389\/fmicb.2019.02892","journal-title":"Front Microbiol"},{"key":"36795_CR8","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1002\/clen.201700019","volume":"615","author":"MC Bastos","year":"2017","unstructured":"Bastos MC, Santos DR, Lima JAMC, Le Guet T, Santanna dos Santos MA, Zanella R, Aubertheau E, Mondamert L, Caner L, Labanowski J (2017) Presence of anthropogenic markers in water: A case study of the Guapor\u00e9 River watershed, Brazil. Sci Total Environ 615:1156\u20131165. https:\/\/doi.org\/10.1002\/clen.201700019","journal-title":"Sci Total Environ"},{"issue":"2","key":"36795_CR9","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/s10661-022-10899-8","volume":"195","author":"MC Bastos","year":"2023","unstructured":"Bastos MC, Rheinheimer DDS, Le Guet T, Brunet JV, Aubertheau E, Mondamert L, Labanowski J (2023) Presence of pharmaceuticals and bacterial resistance genes in river epilithic biofilms exposed to intense agricultural and urban pressure. Environ Monit Assess 195(2):328. https:\/\/doi.org\/10.1007\/s10661-022-10899-8","journal-title":"Environ Monit Assess"},{"issue":"1","key":"36795_CR10","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1186\/s13643-018-0915-2","volume":"7","author":"L Bero","year":"2018","unstructured":"Bero L, Chartres N, Diong J, Fabbri A, Ghersi D, Lam J, Lau A, McDonald S, Mintzes B, Sutton P, Turton JL, Woodruff TJ (2018) The risk of bias in observational studies of exposures (ROBINS-E) tool: concerns arising from application to observational studies of exposures. Syst Rev 7(1):242. https:\/\/doi.org\/10.1186\/s13643-018-0915-2","journal-title":"Syst Rev"},{"key":"36795_CR11","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.jhazmat.2016.11.009","volume":"324","author":"S Biswas","year":"2017","unstructured":"Biswas S, Kranz WL, Shapiro CA, Snow DD, Bartelt-Hunt SL, Mamo M, Tarkalson DD, Zhang TC, Shelton DP, van Donk SJ, Mader TL (2017) Effect of rainfall timing and tillage on the transport of steroid hormones in runoff from manure amended row crop fields. J Hazard Mater 324:436\u2013447. https:\/\/doi.org\/10.1016\/j.jhazmat.2016.11.009","journal-title":"J Hazard Mater"},{"key":"36795_CR12","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1016\/j.scitotenv.2018.12.256","volume":"660","author":"P Branchet","year":"2019","unstructured":"Branchet P, Ariza Castro N, Fenet H, Gomez E, Courant F, Sebag D, Gardon J, Jourdan C, Ngounou Ngatcha B, Kengne I, Cadot E, Gonzalez C (2019) Anthropic impacts on Sub-Saharan urban water resources through their pharmaceutical contamination (Yaound\u00e9, Center Region, Cameroon). Sci Total Environ 660:886\u2013898. https:\/\/doi.org\/10.1016\/j.scitotenv.2018.12.256","journal-title":"Sci Total Environ"},{"key":"36795_CR13","unstructured":"BRASIL (2005) Resolu\u00e7\u00e3o Conama n\u00ba 357, de 17 de mar\u00e7o de 2005. Disp\u00f5e sobre a classifica\u00e7\u00e3o dos corpos de \u00e1gua e diretrizes ambientais para o seu enquadramento, bem como estabelece as condi\u00e7\u00f5es e padr\u00f5es de lan\u00e7amento de efluentes. Di\u00e1rio Oficial da Uni\u00e3o: Bras\u00edlia, DF. https:\/\/www.icmbio.gov.br\/cepsul\/images\/stories\/legislacao\/Resolucao\/2005\/res_conama_357_2005_classificacao_corpos_agua_rtfcda_altrd_res_393_2007_397_2008_410_2009_430_2011.pdf. Accessed 10 November 2024."},{"issue":"4","key":"36795_CR14","doi-asserted-by":"publisher","first-page":"724","DOI":"10.3390\/antibiotics12040724","volume":"12","author":"G Caioni","year":"2023","unstructured":"Caioni G, Benedetti E, Perugini M, Amorena M, Merola C (2023) Personal care products as a contributing factor to antimicrobial resistance: Current state and novel approach to investigation. Antibiotics 12(4):724. https:\/\/doi.org\/10.3390\/antibiotics12040724","journal-title":"Antibiotics"},{"key":"36795_CR15","doi-asserted-by":"publisher","first-page":"2628","DOI":"10.3390\/w11122628","volume":"11","author":"GM Calder\u00f3n-Moreno","year":"2019","unstructured":"Calder\u00f3n-Moreno GM, Vergara-S\u00e1nchez J, Saldarriaga-Nore\u00f1a H, Garc\u00eda-Betancourt ML, Dom\u00ednguez-Pati\u00f1o ML, Moeller-Ch\u00e1vez GE, Ronderos-Lara JG, Arias-Montoya MI, Montoya-Balbas IJ, Murillo-Tovar MA (2019) Occurrence and risk assessment of steroidal hormones and phenolic endocrine disrupting compounds in surface water in Cuautla River. Mexico Water 11:2628. https:\/\/doi.org\/10.3390\/w11122628","journal-title":"Mexico Water"},{"issue":"10","key":"36795_CR16","doi-asserted-by":"publisher","first-page":"7936","DOI":"10.1007\/s11356-014-3929-x","volume":"22","author":"MB Campanha","year":"2015","unstructured":"Campanha MB, Awan AT, de Sousa DN, Grosseli GM, Mozeto AA, Fadini PS (2015) A 3-year study on occurrence of emerging contaminants in an urban stream of S\u00e3o Paulo State of Southeast Brazil. Environ Sci Pollut Res Int 22(10):7936\u20137947. https:\/\/doi.org\/10.1007\/s11356-014-3929-x","journal-title":"Environ Sci Pollut Res Int"},{"key":"36795_CR17","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.scitotenv.2016.10.089","volume":"576","author":"I Campestrini","year":"2017","unstructured":"Campestrini I, Jardim WF (2017) Occurrence of cocaine and benzoylecgonine in drinking and source water in the S\u00e3o Paulo State region, Brazil. Sci Total Environ 576:374\u2013380. https:\/\/doi.org\/10.1016\/j.scitotenv.2016.10.089","journal-title":"Sci Total Environ"},{"issue":"6","key":"36795_CR18","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1590\/S1413-415220200352","volume":"26","author":"JR Chaves","year":"2021","unstructured":"Chaves JR, Teixeira LCGM, Mendon\u00e7a NM, Aquino SF (2021) Investiga\u00e7\u00e3o de cafe\u00edna, genfibrozila, bezafibrato, metformina, prometazina e loratadina em \u00e1guas de sistema de abastecimento p\u00fablico. Eng Sanit Ambient 26(6):1143\u20131154. https:\/\/doi.org\/10.1590\/S1413-415220200352","journal-title":"Eng Sanit Ambient"},{"key":"36795_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.122628","volume":"338","author":"AT de Rezende","year":"2023","unstructured":"de Rezende AT, Mounteer AH (2023) Ecological risk assessment of pharmaceuticals and endocrine disrupting compounds in Brazilian surface waters. Environ Pollut 338. https:\/\/doi.org\/10.1016\/j.envpol.2023.122628","journal-title":"Environ Pollut"},{"issue":"22","key":"36795_CR20","doi-asserted-by":"publisher","first-page":"11765","DOI":"10.3390\/ijerph182211765","volume":"18","author":"SF de Aquino","year":"2021","unstructured":"de Aquino SF, Brandt EMF, Bottrel SEC, Gomes FBR, Silva SQ (2021) Occurrence of pharmaceuticals and endocrine disrupting compounds in Brazilian water and the risks they may represent to human health. Int J Environ Res Public Health 18(22):11765. https:\/\/doi.org\/10.3390\/ijerph182211765","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"36795_CR21","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s10661-019-7990-2","volume":"192","author":"JF de Fran\u00e7a","year":"2019","unstructured":"de Fran\u00e7a JF, Pickler TB, Jozala AF, dos Santos CA, Batista BL, Pedron T, Vieira RAL, Grotto D (2019) Determination of 17\u03b1-ethinylestradiol and toxic metals in surface waters, and estimation of daily intake. Environ Monit Assess 192(1):21. https:\/\/doi.org\/10.1007\/s10661-019-7990-2","journal-title":"Environ Monit Assess"},{"key":"36795_CR22","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1007\/s11270-020-04835-0","volume":"231","author":"CR Derisso","year":"2020","unstructured":"Derisso CR, Pompei CME, Spadoto M, Pinto TS, Vieira EM (2020) Occurrence of parabens in surface water, wastewater treatment plant in southeast of Brazil and assessment of their environmental risk. Water Air Soil Pollut 231:468. https:\/\/doi.org\/10.1007\/s11270-020-04835-0","journal-title":"Water Air Soil Pollut"},{"key":"36795_CR23","doi-asserted-by":"publisher","unstructured":"do Nascimento R F, de Carvalho F J A A, Napole\u00e3o D C, Ribeiro B G, Cabral J J S P & de Paiva A L R. (2023). Presence of non-steroidal anti-inflammatories in Brazilian semiarid waters. Water, Air, & Soil Pollution, 234(4), 225. https:\/\/doi.org\/10.1007\/s11270-023-06239-2","DOI":"10.1007\/s11270-023-06239-2"},{"issue":"31","key":"36795_CR24","doi-asserted-by":"publisher","first-page":"44080","DOI":"10.1007\/s11356-024-33967-7","volume":"31","author":"P Dom\u00ednguez-Garc\u00eda","year":"2024","unstructured":"Dom\u00ednguez-Garc\u00eda P, Fern\u00e1ndez-Ruano L, B\u00e1guena J, Cuadros J, G\u00f3mez-Canela C (2024) Assessing the pharmaceutical residues as hotspots of the main rivers of Catalonia, Spain. Environ Sci Pollut Res Int 31(31):44080\u201344095. https:\/\/doi.org\/10.1007\/s11356-024-33967-7","journal-title":"Environ Sci Pollut Res Int"},{"issue":"3","key":"36795_CR25","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1590\/2318-0331.011616018","volume":"21","author":"MM dos Santos","year":"2016","unstructured":"dos Santos MM, Brehm FdeA, Filippe TC, Knapik HG, de Azevedo JCR (2016) Occurrence and risk assessment of parabens and triclosan in surface waters of southern Brazil: a problem of emerging compounds in an emerging country. Rev Bras Recursos H\u00eddricos 21(3):603\u2013617. https:\/\/doi.org\/10.1590\/2318-0331.011616018","journal-title":"Rev Bras Recursos H\u00eddricos"},{"key":"36795_CR26","doi-asserted-by":"publisher","unstructured":"dos Santos I R, da Silva I N M, de Oliveira J R, de Oliveira N R, de Sousa A R V, de Melo A M, de Paula J A M, do Amaral C L, Silveira-Lacerda E P, da Cunha L C & Bail\u00e3o E F L C. (2023). The presence of antibiotics and multidrug-resistant Staphylococcus aureus reservoir in a low-order stream spring in central Brazil. Brazilian Journal of Microbiology, 54(2), 997\u20131007. https:\/\/doi.org\/10.1007\/s42770-023-00973-9","DOI":"10.1007\/s42770-023-00973-9"},{"issue":"22","key":"36795_CR27","doi-asserted-by":"publisher","first-page":"11275","DOI":"10.1021\/acs.est.5c05363","volume":"59","author":"J Du","year":"2025","unstructured":"Du J, Xu J, Luo Y, Li X, Zhao L, Liu S, Jia X, Wang Z, Ge L, Cui K, Ga Y, Zhu M, Ji T, Huang Z, Xia X (2025) High-throughput monitoring of 323 pharmaceuticals and personal care products (PPCPs) and pesticides in surface water for environmental risk assessment. Environ Sci Technol 59(22):11275\u201311285. https:\/\/doi.org\/10.1021\/acs.est.5c05363","journal-title":"Environ Sci Technol"},{"key":"36795_CR28","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s00244-020-00760-9","volume":"79","author":"P Emnet","year":"2020","unstructured":"Emnet P, Mahaliyana AS, Northcott G, Gaw S (2020) Organic micropollutants in wastewater effluents and the receiving coastal waters, sediments, and biota of Lyttelton Harbour (Te Whakaraup\u014d), New Zealand. Arch Environ Contam Toxicol 79:461\u2013477. https:\/\/doi.org\/10.1007\/s00244-020-00760-9","journal-title":"Arch Environ Contam Toxicol"},{"key":"36795_CR29","unstructured":"European Parliament & Council of the European Union (2006). Regulation (EC) No 1907\/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH). Official Journal of the European Union, L396\/1. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/HTML\/?uri=LEGISSUM:chemicals_regulatory_framework. Accessed 10 November 2024."},{"key":"36795_CR30","unstructured":"European Parliament & Council of the European Union (2000). Directive 2000\/60\/EC of the European Parliament and of the Council establishing a framework for Community action in the field of water policy. EUR-Lex. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=CELEX:02000L0060-20141120. Accessed 10 November 2024."},{"key":"36795_CR31","doi-asserted-by":"publisher","unstructured":"Fahimipour A K, Ben M S, McFarland A G, Blaustein R A, Chen J, Glawe A J, Kline J, Green J L, Halden R U, Van Den Wymelenberg K, Huttenhower C & [\u00faltimo autor n\u00e3o informado]. (2018). Antimicrobial chemicals associate with microbial function and antibiotic resistance indoors. mSystems, 3, e00200\u201318. https:\/\/doi.org\/10.1128\/mSystems.00200-18","DOI":"10.1128\/mSystems.00200-18"},{"key":"36795_CR32","unstructured":"FAO, UNEP, WHO, and WOAH (2022). Global Plan of Action on One Health. Towards a more comprehensive One Health approach to global health threats at the human-animal-environment interface. Rome. https:\/\/www.who.int\/publications\/i\/item\/9789240059139. Accessed 10 November 2024."},{"key":"36795_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.139827","volume":"739","author":"ML Feo","year":"2020","unstructured":"Feo ML, Bagnati R, Passoni A, Riva F, Salvagio Manta D, Sprovieri M, Traina A, Zuccato E, Castiglioni S (2020) Pharmaceuticals and other contaminants in waters and sediments from Augusta Bay (southern Italy). Sci Total Environ 739. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.139827","journal-title":"Sci Total Environ"},{"key":"36795_CR34","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.chemosphere.2019.02.041","volume":"224","author":"J Fern\u00e1ndez-Rubio","year":"2019","unstructured":"Fern\u00e1ndez-Rubio J, Rodr\u00edguez-Gil JL, Postigo C, Mastroianni N, L\u00f3pez de Alda M, Barcel\u00f3 D, Valc\u00e1rcel Y (2019) Psychoactive pharmaceuticals and illicit drugs in coastal waters of North-western Spain: environmental exposure and risk assessment. Chemosphere 224:379\u2013389. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.02.041","journal-title":"Chemosphere"},{"key":"36795_CR35","doi-asserted-by":"publisher","unstructured":"Ferreira A P (2018). Environmental Investigation of Psychiatric Pharmaceuticals: Guandu River, Rio De Janeiro State, Southeast Brazil. Journal of Chemical Health Risks, 3(4), 0\u20130. https:\/\/doi.org\/10.22034\/jchr.2018.544072","DOI":"10.22034\/jchr.2018.544072"},{"issue":"4","key":"36795_CR36","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1080\/09603120500155898","volume":"15","author":"AP Ferreira","year":"2005","unstructured":"Ferreira AP, da Cunha CL (2005) Anthropic pollution in aquatic environment: development of a caffeine indicator. Int J Environ Health Res 15(4):303\u2013311. https:\/\/doi.org\/10.1080\/09603120500155898","journal-title":"Int J Environ Health Res"},{"key":"36795_CR37","doi-asserted-by":"publisher","unstructured":"Filippe T C, Goulart F A B, Mizukawa A & de Azevedo J C R. (2018). Validation of analytical methodology for determination of personal care products in environmental matrix by GC-MSMS. Ecl\u00e9tica Qu\u00edmica, 43(3), 30\u201336. https:\/\/doi.org\/10.26850\/1678-4618eqj.v43.3.2018.p30-36","DOI":"10.26850\/1678-4618eqj.v43.3.2018.p30-36"},{"key":"36795_CR38","doi-asserted-by":"publisher","first-page":"30998","DOI":"10.1007\/s11356-020-08375-2","volume":"27","author":"MK Fontes","year":"2020","unstructured":"Fontes MK, Maranho LA, Pereira CDS (2020) Review on the occurrence and biological effects of illicit drugs in aquatic ecosystems. Environ Sci Pollut Res 27:30998\u201331034. https:\/\/doi.org\/10.1007\/s11356-020-08375-2","journal-title":"Environ Sci Pollut Res"},{"key":"36795_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.143808","volume":"757","author":"MK Fontes","year":"2021","unstructured":"Fontes MK, de Campos BG, Cortez FS, Pusceddu FH, Nobre CR, Moreno BB, Lebre DT, Maranho LA, Pereira CDS (2021) Mussels get higher: a study on the occurrence of cocaine and benzoylecgonine in seawater, sediment and mussels from a subtropical ecosystem (Santos Bay, Brazil). Sci Total Environ 757. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.143808","journal-title":"Sci Total Environ"},{"key":"36795_CR40","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.seppur.2018.11.018","volume":"212","author":"AFS Foureaux","year":"2019","unstructured":"Foureaux AFS, Reis EO, Lebron Y, Moreira V, Santos LV, Amaral MS, Lange LC (2019) Rejection of pharmaceutical compounds from surface water by nanofiltration and reverse osmosis. Sep Purif Technol 212:171\u2013179. https:\/\/doi.org\/10.1016\/j.seppur.2018.11.018","journal-title":"Sep Purif Technol"},{"key":"36795_CR41","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1016\/j.envpol.2018.06.048","volume":"241","author":"M Fujimoto","year":"2018","unstructured":"Fujimoto M, Carey DE, McNamara PJ (2018) Metagenomics reveal triclosan-induced changes in the antibiotic resistome of anaerobic digesters. Environ Pollut 241:1182\u20131190. https:\/\/doi.org\/10.1016\/j.envpol.2018.06.048","journal-title":"Environ Pollut"},{"issue":"11","key":"36795_CR42","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.5935\/0103-5053.20150206","volume":"26","author":"CA Galinaro","year":"2015","unstructured":"Galinaro CA, Pereira FM, Vieira EM (2015) Determination of parabens in surface water from Mogi Gua\u00e7u River (S\u00e3o Paulo, Brazil) using dispersive liquid-liquid microextraction based on low density solvent and LC-DAD. J Braz Chem Soc 26(11):2205\u20132213. https:\/\/doi.org\/10.5935\/0103-5053.20150206","journal-title":"J Braz Chem Soc"},{"key":"36795_CR43","doi-asserted-by":"publisher","first-page":"8816","DOI":"10.1007\/s11356-021-16315-x","volume":"29","author":"CA Galinaro","year":"2022","unstructured":"Galinaro CA, Spadoto M, de Aquino FWB, Pelinson NS, Vieira EM (2022) Environmental risk assessment of parabens in surface water from a Brazilian river: the case of Mogi Gua\u00e7u Basin, S\u00e3o Paulo State, under precipitation anomalies. Environ Sci Pollut Res 29:8816\u20138830. https:\/\/doi.org\/10.1007\/s11356-021-16315-x","journal-title":"Environ Sci Pollut Res"},{"key":"36795_CR44","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1016\/j.scitotenv.2018.06.263","volume":"643","author":"IB Gomes","year":"2018","unstructured":"Gomes IB, Sim\u00f5es LC, Sim\u00f5es M (2018) The effects of emerging environmental contaminants on Stenotrophomonas maltophilia isolated from drinking water in planktonic and sessile states. Sci Total Environ 643:1348\u20131356. https:\/\/doi.org\/10.1016\/j.scitotenv.2018.06.263","journal-title":"Sci Total Environ"},{"key":"36795_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fenvs.2021.801599","volume":"9","author":"MP Gomes","year":"2021","unstructured":"Gomes MP, Brito JCM, Vieira F, Kitamura RSA, Juneau P (2021) Emerging contaminants in streams of Doce River watershed, Minas Gerais. Brazil Frontiers in Environmental Science 9. https:\/\/doi.org\/10.3389\/fenvs.2021.801599","journal-title":"Brazil Frontiers in Environmental Science"},{"key":"36795_CR46","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.160638","volume":"861","author":"MDC G\u00f3mez-Regalado","year":"2023","unstructured":"G\u00f3mez-Regalado MDC, Mart\u00edn J, Santos JL, Aparicio I, Alonso E, Zafra-G\u00f3mez A (2023) Bioaccumulation\/bioconcentration of pharmaceutical active compounds in aquatic organisms: assessment and factors database. Sci Total Environ 861. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.160638","journal-title":"Sci Total Environ"},{"issue":"26","key":"36795_CR47","doi-asserted-by":"publisher","first-page":"37907","DOI":"10.1007\/s11356-024-33713-z","volume":"31","author":"M Grzegorzek","year":"2024","unstructured":"Grzegorzek M, Wartalska K, Kowalik R (2024) Occurrence and sources of hormones in water resources\u2014environmental and health impact. Environ Sci Pollut Res 31(26):37907\u201337922. https:\/\/doi.org\/10.1007\/s11356-024-33713-z","journal-title":"Environ Sci Pollut Res"},{"key":"36795_CR48","doi-asserted-by":"publisher","first-page":"9807","DOI":"10.1021\/acs.est.6b00262","volume":"50","author":"EM Hartmann","year":"2016","unstructured":"Hartmann EM, Hickey R, Hsu T, Betancourt Rom\u00e1n CM, Chen J, Schwager R, Kline J, Brown GZ, Halden RU, Huttenhower C, Green JL (2016) Antimicrobial chemicals are associated with elevated antibiotic resistance genes in the indoor dust microbiome. Environ Sci Technol 50:9807\u20139815. https:\/\/doi.org\/10.1021\/acs.est.6b00262","journal-title":"Environ Sci Technol"},{"issue":"9","key":"36795_CR49","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1038\/s41564-019-0503-9","volume":"4","author":"S Hernando-Amado","year":"2019","unstructured":"Hernando-Amado S, Coque TM, Baquero F, Mart\u00ednez JL (2019) Defining and combating antibiotic resistance from one health and global health perspectives. Nat Microbiol 4(9):1432\u20131442. https:\/\/doi.org\/10.1038\/s41564-019-0503-9","journal-title":"Nat Microbiol"},{"key":"36795_CR50","doi-asserted-by":"publisher","unstructured":"Higgins J P T, Thomas J, Chandler J, Cumpston M, Li T, Page M J & Welch V A (Eds.). (2019). Cochrane Handbook for Systematic Reviews of Interventions (2nd ed.). John Wiley & Sons, Chichester, UK. https:\/\/doi.org\/10.1002\/9781119536604","DOI":"10.1002\/9781119536604"},{"key":"36795_CR51","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2024.108602","volume":"186","author":"JPT Higgins","year":"2024","unstructured":"Higgins JPT, Morgan RL, Rooney AA, Taylor KW, Thayer KA, Silva RA, Lemeris C, Akl EA, Bateson TF, Berkman ND, Glenn BS, Hr\u00f3bjartsson A, LaKind JS, McAleenan A, Meerpohl JJ, Nachman RM, Obbagy JE, O\u2019Connor A, Radke EG, Savovi\u0107 J, Sterne JAC (2024) A tool to assess risk of bias in non-randomized follow-up studies of exposure effects (ROBINS-E). Environ Int 186. https:\/\/doi.org\/10.1016\/j.envint.2024.108602","journal-title":"Environ Int"},{"key":"36795_CR52","doi-asserted-by":"publisher","DOI":"10.1007\/s11783-019-1140-5","volume":"13","author":"P Hu","year":"2019","unstructured":"Hu P, Guo C, Zhang Y, Lv J, Zhang Y, Xu J (2019) Occurrence, distribution and risk assessment of abused drugs and their metabolites in a typical urban river in north China. Front Environ Sci Eng 13. https:\/\/doi.org\/10.1007\/s11783-019-1140-5","journal-title":"Front Environ Sci Eng"},{"key":"36795_CR53","doi-asserted-by":"publisher","unstructured":"Ide A H, Osawa R A, Marcante L O, Pereira J C & de Azevedo J C R. (2017). Occurrence of pharmaceutical products, female sex hormones and caffeine in a subtropical region in Brazil. CLEAN: Soil, Air, Water, 45(9), 1700334. https:\/\/doi.org\/10.1002\/clen.201700334","DOI":"10.1002\/clen.201700334"},{"issue":"10","key":"36795_CR54","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1080\/03067319.2014.914184","volume":"94","author":"L Jank","year":"2014","unstructured":"Jank L, Hoff RB, da Costa FJ, Pizzolato TM (2014) Simultaneous determination of eight antibiotics from distinct classes in surface and wastewater samples by solid-phase extraction and high-performance liquid chromatography\u2013electrospray ionisation mass spectrometry. Int J Environ Anal Chem 94(10):1013\u20131037. https:\/\/doi.org\/10.1080\/03067319.2014.914184","journal-title":"Int J Environ Anal Chem"},{"key":"36795_CR55","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.seppur.2011.06.020","volume":"84","author":"WF Jardim","year":"2012","unstructured":"Jardim WF, Montagner CC, Pescara IC, Umbuzeiro GA, Bergamasco AMDD, Eldridge ML, Sodr\u00e9 FF (2012) An integrated approach to evaluate emerging contaminants in drinking water. Sep Purif Technol 84:3\u20138. https:\/\/doi.org\/10.1016\/j.seppur.2011.06.020","journal-title":"Sep Purif Technol"},{"key":"36795_CR56","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.envint.2018.07.046","volume":"120","author":"M Jin","year":"2018","unstructured":"Jin M, Lu J, Chen Z, Nguyen SH, Mao L, Li J, Yuan Z, Guo J (2018) Antidepressant fluoxetine induces multiple antibiotics resistance in Escherichia coli via ROS-mediated mutagenesis. Environ Int 120:421\u2013430. https:\/\/doi.org\/10.1016\/j.envint.2018.07.046","journal-title":"Environ Int"},{"issue":"8","key":"36795_CR57","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.001384","volume":"169","author":"M Kelbrick","year":"2023","unstructured":"Kelbrick M, Hesse E, O\u2019Brien S (2023) Cultivating antimicrobial resistance: how intensive agriculture ploughs the way for antibiotic resistance. Microbiology 169(8). https:\/\/doi.org\/10.1099\/mic.0.001384","journal-title":"Microbiology"},{"issue":"15","key":"36795_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e34825","volume":"10","author":"D K\u00f6tke","year":"2024","unstructured":"K\u00f6tke D, Gandrass J, Bento CPM, Ferreira CSS, Ferreira AJD (2024) Occurrence and environmental risk assessment of pharmaceuticals in the Mondego River (Portugal). Heliyon 10(15). https:\/\/doi.org\/10.1016\/j.heliyon.2024.e34825","journal-title":"Heliyon"},{"issue":"Pt 2","key":"36795_CR59","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2022.137091","volume":"311","author":"RY Krishnan","year":"2023","unstructured":"Krishnan RY, Manikandan S, Subbaiya R, Biruntha M, Balachandar R, Karmegam N (2023) Origin, transport and ecological risk assessment of illicit drugs in the environment - a review. Chemosphere 311(Pt 2). https:\/\/doi.org\/10.1016\/j.chemosphere.2022.137091","journal-title":"Chemosphere"},{"key":"36795_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2024.123764","volume":"347","author":"L Lahens","year":"2024","unstructured":"Lahens L, Cabana H, Huot Y, Segura PA (2024) Trace organic contaminants in lake waters: occurrence and environmental risk assessment at the national scale in Canada. Environ Pollut 347. https:\/\/doi.org\/10.1016\/j.envpol.2024.123764","journal-title":"Environ Pollut"},{"key":"36795_CR61","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.116420","volume":"278","author":"X Li","year":"2024","unstructured":"Li X, Shen X, Jiang W, Xi Y, Li S (2024) Comprehensive review of emerging contaminants: detection technologies, environmental impact, and management strategies. Ecotoxicol Environ Saf 278. https:\/\/doi.org\/10.1016\/j.ecoenv.2024.116420","journal-title":"Ecotoxicol Environ Saf"},{"key":"36795_CR62","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2024.122473","volume":"267","author":"Y Liu","year":"2024","unstructured":"Liu Y, Chen H, Zhang Y, Liu C, Song L (2024) Metagenomics-resolved genomics provide novel ecological insights into resistome community coalescence of wastewater in river environment. Water Res 267. https:\/\/doi.org\/10.1016\/j.watres.2024.122473","journal-title":"Water Res"},{"issue":"1","key":"36795_CR63","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.marpolbul.2016.05.059","volume":"110","author":"VSA Lopes","year":"2016","unstructured":"Lopes VSA, Riente RR, da Silva AA, Torquilho DF, Carreira RS, Marques MRC (2016) Development of a solid-phase extraction system modified for preconcentration of emerging contaminants in large sample volumes from rivers of the lagoon system in the city of Rio de Janeiro. Brazil Marine Pollution Bulletin 110(1):572\u2013577. https:\/\/doi.org\/10.1016\/j.marpolbul.2016.05.059","journal-title":"Brazil Marine Pollution Bulletin"},{"issue":"3","key":"36795_CR64","doi-asserted-by":"publisher","first-page":"421","DOI":"10.4025\/actascitechnol.v36i3.18477","volume":"36","author":"KS Machado","year":"2014","unstructured":"Machado KS, Cardoso FD, Azevedo JCR, Borba Braga C (2014) Occurrence of female sexual hormones in the Iguazu River basin, Curitiba, Paran\u00e1 State, Brazil. Acta Sci Technol 36(3):421\u2013427","journal-title":"Acta Sci Technol"},{"key":"36795_CR65","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.scitotenv.2016.07.210","volume":"572","author":"KC Machado","year":"2016","unstructured":"Machado KC, Grassi MT, Vidal C, Pescara IC, Jardim WF, Fernandes AN, Sodr\u00e9 FF, Almeida FV, Santana JS, Canela MC, Nunes CRO, Bichinho KM, Severo FJR (2016) A preliminary nationwide survey of the presence of emerging contaminants in drinking and source waters in Brazil. Sci Total Environ 572:138\u2013146. https:\/\/doi.org\/10.1016\/j.scitotenv.2016.07.210","journal-title":"Sci Total Environ"},{"issue":"Pt 1","key":"36795_CR66","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.159376","volume":"857","author":"EC Machado","year":"2023","unstructured":"Machado EC, Freitas DL, Leal CD, Oliveira AT, Zerbini A, Chernicharo CA, Ara\u00fajo JC (2023) Antibiotic resistance profile of wastewater treatment plants in Brazil reveals different patterns of resistance and multi resistant bacteria in final effluents. Sci Total Environ 857(Pt 1). https:\/\/doi.org\/10.1016\/j.scitotenv.2022.159376","journal-title":"Sci Total Environ"},{"issue":"3","key":"36795_CR67","doi-asserted-by":"publisher","first-page":"475","DOI":"10.20937\/RICA.2018.34.03.10","volume":"34","author":"CA Madera-Parra","year":"2018","unstructured":"Madera-Parra CA, Jim\u00e9nez-Bambague EM, Toro-V\u00e9lez AF, Lara-Borrero JA, Bedoya-R\u00edos DF, Duque-Pardo V (2018) Estudio exploratorio de la presencia de microcontaminantes en el ciclo urbano del agua en Colombia: caso de estudio Santiago de Cali. Rev Int Contam Ambient 34(3):475\u2013487. https:\/\/doi.org\/10.20937\/RICA.2018.34.03.10","journal-title":"Rev Int Contam Ambient"},{"key":"36795_CR68","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1007\/s12665-016-5629-y","volume":"75","author":"NY Mar da Costa","year":"2016","unstructured":"Mar da Costa NY, Boaventura GR, Mulholland DS, Ara\u00fajo DF, Moreira RCA, Faial KCF, Bomfim EO (2016) Biogeochemical mechanisms controlling trophic state and micropollutant concentrations in a tropical artificial lake. Environmental Earth Sciences 75:854. https:\/\/doi.org\/10.1007\/s12665-016-5629-y","journal-title":"Environmental Earth Sciences"},{"key":"36795_CR69","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2019.112944","volume":"178","author":"DP Masemola","year":"2020","unstructured":"Masemola DP, Nxumalo EN, Nyoni H, Nkambule TTI, Mamba BB, Msagati TAM (2020) The occurrence and exposure risk assessment of psychoactive drug residues and metabolites in aquatic environment. J Pharm Biomed Anal 178. https:\/\/doi.org\/10.1016\/j.jpba.2019.112944","journal-title":"J Pharm Biomed Anal"},{"key":"36795_CR70","doi-asserted-by":"publisher","unstructured":"McGuinness LA, Higgins JPT (2020) Risk-of-bias visualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods. https:\/\/doi.org\/10.1002\/jrsm.1411","DOI":"10.1002\/jrsm.1411"},{"key":"36795_CR71","doi-asserted-by":"publisher","unstructured":"Melo J, Santana J & Silva G (2017). A contribui\u00e7\u00e3o da infraestrutura de pesquisa na gera\u00e7\u00e3o de ci\u00eancia e tecnologia em regi\u00f5es brasileiras. Revista Desafios \u2013 Revista Interdisciplinar da Universidade Federal do Tocantins, 4(4), 167\u2013179. https:\/\/doi.org\/10.20873\/uft.2359-3652.2017v4n4p167","DOI":"10.20873\/uft.2359-3652.2017v4n4p167"},{"key":"36795_CR72","doi-asserted-by":"publisher","DOI":"10.1590\/S2179-975X7022","volume":"35","author":"A Minillo","year":"2023","unstructured":"Minillo A, Isique WD, Cardoso CAL, S\u00faarez YR (2023) Occurrence and ecological risk assessment of pharmaceutically active compounds in neotropical small basins. Brazil. Acta Limnol Bras 35. https:\/\/doi.org\/10.1590\/S2179-975X7022","journal-title":"Acta Limnol Bras"},{"issue":"11","key":"36795_CR73","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1089\/ees.2018.006","volume":"35","author":"A Mizukawa","year":"2018","unstructured":"Mizukawa A, Reichert G, Filippe TC, Rodrigues de Azevedo JC, Umbuzeiro GA (2018) Occurrence and Risk Assessment of Personal Care Products in Subtropical Urban Rivers. Environ Eng Sci 35(11):1263\u20131272. https:\/\/doi.org\/10.1089\/ees.2018.006","journal-title":"Environ Eng Sci"},{"key":"36795_CR74","doi-asserted-by":"publisher","first-page":"230","DOI":"10.4236\/jep.2016.72020","volume":"7","author":"MA Monteiro","year":"2016","unstructured":"Monteiro MA, Spisso BF, Santos JRMP, Costa RP, Ferreira RG, Pereira MU, Miranda TS, Andrade BRG, d\u2019Avila LA, Malm O (2016) Occurrence of antimicrobials in river water samples from rural region of the State of Rio de Janeiro, Brazil. J Environ Prot 7:230\u2013241. https:\/\/doi.org\/10.4236\/jep.2016.72020","journal-title":"J Environ Prot"},{"key":"36795_CR75","doi-asserted-by":"publisher","unstructured":"Monteiro M A, Spisso B F, Ferreira R G, Cabral L A G, Pereira N R A, Almeida D C, Nascimento E S, Silva D C, Torres J P M & Malm O. (2018). Development and validation of liquid chromatography-tandem mass spectrometry methods for determination of beta-lactams, macrolides, fluoroquinolones, sulfonamides and tetracyclines in surface and drinking water from Rio de Janeiro, Brazil. Journal of the Brazilian Chemical Society, 29(4), 801\u2013813. https:\/\/doi.org\/10.21577\/0103-5053.20170203","DOI":"10.21577\/0103-5053.20170203"},{"key":"36795_CR76","unstructured":"Sistema Nacional de Informa\u00e7\u00f5es sobre Saneamento \u2013 SNIS (2022). Painel de Informa\u00e7\u00f5es sobre Saneamento. Minist\u00e9rio das Cidades. Available at: https:\/\/www.gov.br\/cidades\/pt-br\/acesso-a-informacao\/acoes-e-programas\/saneamento\/snis\/painel\/es. Accessed on: 10 November 2024."},{"key":"36795_CR77","doi-asserted-by":"publisher","first-page":"787","DOI":"10.3390\/w13060787","volume":"13","author":"DA Narzetti","year":"2021","unstructured":"Narzetti DA, Marques RC (2021) Access to water and sanitation services in Brazilian vulnerable areas: the role of regulation and recent institutional reform. Water 13:787. https:\/\/doi.org\/10.3390\/w13060787","journal-title":"Water"},{"key":"36795_CR78","doi-asserted-by":"publisher","unstructured":"Nascimento S and Cass Q. (2021) An Online Solid Phase Extraction-Liquid Chromatography Tandem Mass Spectrometry Method for the Analysis of Parabens in Urban Waters. Journal of the Brazilian Chemical Society, 32(5), 978\u201388. https:\/\/doi.org\/10.21577\/0103-5053.20200246","DOI":"10.21577\/0103-5053.20200246"},{"key":"36795_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.143720","volume":"757","author":"B Ng","year":"2021","unstructured":"Ng B, Quinete N, Maldonado S, Lugo K, Purrinos J, Brice\u00f1o H, Gardinali P (2021) Understanding the occurrence and distribution of emerging pollutants and endocrine disruptors in sensitive coastal South Florida ecosystems. Sci Total Environ 757. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.143720","journal-title":"Sci Total Environ"},{"key":"36795_CR80","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.3390\/w11051071","volume":"11","author":"K Paciuszkiewicz","year":"2019","unstructured":"Paciuszkiewicz K, Ryan M, Wright IA, Reynolds JK (2019) Variations in illicit compound discharged from treated wastewater. Water 11:1071. https:\/\/doi.org\/10.3390\/w11051071","journal-title":"Water"},{"key":"36795_CR81","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hr\u00f3bjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"BMJ"},{"issue":"16","key":"36795_CR82","doi-asserted-by":"publisher","first-page":"15774","DOI":"10.1007\/s11356-018-1649-3","volume":"25","author":"GP Peteffi","year":"2018","unstructured":"Peteffi GP, Fleck JD, Kael IM, Girardi V, B\u00fcndchen R, Krajeski DM, Demoliner M, Silva FP, da Rosa DC, Antunes MV, Linden R (2018) Caffeine levels as a predictor of Human mastadenovirus presence in surface waters\u2014a case study in the Sinos River basin-Brazil. Environ Sci Pollut Res Int 25(16):15774\u201315784. https:\/\/doi.org\/10.1007\/s11356-018-1649-3","journal-title":"Environ Sci Pollut Res Int"},{"issue":"12","key":"36795_CR83","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.3390\/antibiotics11121700","volume":"11","author":"I Pinto","year":"2022","unstructured":"Pinto I, Sim\u00f5es M, Gomes IB (2022) An overview of the impact of pharmaceuticals on aquatic microbial communities. Antibiotics 11(12):1700. https:\/\/doi.org\/10.3390\/antibiotics11121700","journal-title":"Antibiotics"},{"issue":"42","key":"36795_CR84","doi-asserted-by":"publisher","first-page":"63099","DOI":"10.1007\/s11356-022-20312-z","volume":"29","author":"AM Pisetta","year":"2022","unstructured":"Pisetta AM, Roveri V, Guimar\u00e3es LL, Novais de Oliveira TM, Correia AT (2022) First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment. Environ Sci Pollut Res Int 29(42):63099\u201363111. https:\/\/doi.org\/10.1007\/s11356-022-20312-z","journal-title":"Environ Sci Pollut Res Int"},{"key":"36795_CR85","doi-asserted-by":"publisher","unstructured":"Pivetta G G & do Carmo C G M (2019). Presence of emerging contaminants in urban water bodies in southern Brazil. Journal of Water and Health, 17(2), 329\u2013337. https:\/\/doi.org\/10.2166\/wh.2019.092","DOI":"10.2166\/wh.2019.092"},{"key":"36795_CR86","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138661","volume":"727","author":"RC Pivetta","year":"2020","unstructured":"Pivetta RC, Rodrigues-Silva C, Ribeiro AR, Rath S (2020) Tracking the occurrence of psychotropic pharmaceuticals in Brazilian wastewater treatment plants and surface water, with assessment of environmental risks. Sci Total Environ 727. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.138661","journal-title":"Sci Total Environ"},{"key":"36795_CR87","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.chemosphere.2019.03.122","volume":"226","author":"CME Pompei","year":"2019","unstructured":"Pompei CME, Campos LC, da Silva BF, Fogo JC, Vieira EM (2019) Occurrence of PPCPs in a Brazilian water reservoir and their removal efficiency by ecological filtration. Chemosphere 226:210\u2013219. https:\/\/doi.org\/10.1016\/j.chemosphere.2019.03.122","journal-title":"Chemosphere"},{"issue":"6","key":"36795_CR88","doi-asserted-by":"publisher","first-page":"3736","DOI":"10.1021\/acs.est.0c07609","volume":"55","author":"A Previ\u0161i\u0107","year":"2021","unstructured":"Previ\u0161i\u0107 A, Vilenica M, Vu\u010dkovi\u0107 N, Petrovi\u0107 M, Ro\u017eman M (2021) Aquatic insects transfer pharmaceuticals and endocrine disruptors from aquatic to terrestrial ecosystems. Environ Sci Technol 55(6):3736\u20133746. https:\/\/doi.org\/10.1021\/acs.est.0c07609","journal-title":"Environ Sci Technol"},{"key":"36795_CR89","unstructured":"European Commission (2022). Proposal for amending the water directives. European Commission. https:\/\/environment.ec.europa.eu\/publications\/proposal-amending-water-directives_en. Accessed 10 November 2024."},{"issue":"1","key":"36795_CR90","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1007\/s00244-021-00853-z","volume":"81","author":"GR Quadra","year":"2021","unstructured":"Quadra GR, Li Z, Silva PSA, Barros N, Roland F, Sobek A (2021) Temporal and spatial variability of micropollutants in a Brazilian urban river. Arch Environ Contam Toxicol 81(1):142\u2013154. https:\/\/doi.org\/10.1007\/s00244-021-00853-z","journal-title":"Arch Environ Contam Toxicol"},{"key":"36795_CR91","doi-asserted-by":"publisher","unstructured":"Quadra G R, Zhe L i & Barros N (2021). Micropollutants in four Brazilian water reservoirs. Limnologica, 90, 125902. https:\/\/doi.org\/10.1016\/j.limno.2021.125902","DOI":"10.1016\/j.limno.2021.125902"},{"key":"36795_CR92","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s11270-020-04508-y","volume":"231","author":"G Reichert","year":"2020","unstructured":"Reichert G, Mizukawa A, Antonelli J, Goulart FAB, Filippe TC, Rodrigues de Azevedo JC (2020) Determination of parabens, triclosan, and lipid regulators in a subtropical urban river: effects of urban occupation. Water Air Soil Pollut 231:133. https:\/\/doi.org\/10.1007\/s11270-020-04508-y","journal-title":"Water Air Soil Pollut"},{"key":"36795_CR93","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.137556","volume":"489","author":"C Ren","year":"2025","unstructured":"Ren C, Fang Q, Long H, Liu F, Lan W, Gao G (2025) Pollution characteristics, sources and ecological risks of steroid hormones in Fangchenggang Bay, South China Sea: significant impacts of rivers and domestic sewage entering the sea. J Hazard Mater 489. https:\/\/doi.org\/10.1016\/j.jhazmat.2025.137556","journal-title":"J Hazard Mater"},{"key":"36795_CR94","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106702","volume":"155","author":"A Rico","year":"2021","unstructured":"Rico A, de Oliveira R, de Souza NGS, Rizzi C, Villa S, L\u00f3pez-Heras I, Vighi M, Waichman AV (2021) Pharmaceuticals and other urban contaminants threaten Amazonian freshwater ecosystems. Environmental International 155. https:\/\/doi.org\/10.1016\/j.envint.2021.106702","journal-title":"Environmental International"},{"key":"36795_CR95","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1016\/j.scitotenv.2017.09.134","volume":"613\u2013614","author":"JA Rivera-Jaimes","year":"2018","unstructured":"Rivera-Jaimes JA, Postigo C, Melgoza-Alem\u00e1n RM, Ace\u00f1a J, Barcel\u00f3 D, L\u00f3pez de Alda M (2018) Study of pharmaceuticals in surface and wastewater from Cuernavaca, Morelos, Mexico: Occurrence and environmental risk assessment. Sci Total Environ 613\u2013614:1263\u20131274. https:\/\/doi.org\/10.1016\/j.scitotenv.2017.09.134","journal-title":"Sci Total Environ"},{"issue":"23","key":"36795_CR96","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph192315798","volume":"19","author":"J Rogowska","year":"2022","unstructured":"Rogowska J, Zimmermann A (2022) Household pharmaceutical waste disposal as a global problem-a review. Int J Environ Res Public Health 19(23). https:\/\/doi.org\/10.3390\/ijerph192315798","journal-title":"Int J Environ Res Public Health"},{"issue":"9","key":"36795_CR97","doi-asserted-by":"publisher","first-page":"11384","DOI":"10.1007\/s11356-020-11320-y","volume":"28","author":"V Roveri","year":"2021","unstructured":"Roveri V, Guimar\u00e3es LL, Toma W, Correia AT (2021) Occurrence and risk assessment of pharmaceuticals and cocaine around the coastal submarine sewage outfall in Guaruj\u00e1, S\u00e3o Paulo State, Brazil. Environ Sci Pollut Res Int 28(9):11384\u201311400. https:\/\/doi.org\/10.1007\/s11356-020-11320-y","journal-title":"Environ Sci Pollut Res Int"},{"issue":"1","key":"36795_CR98","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1007\/s10646-020-02304-2","volume":"30","author":"JA Sabino","year":"2021","unstructured":"Sabino JA, de S\u00e1 SAL, de Oliveira MCPM, Coutinho R, Marques M (2021) Occurrence of organic micropollutants in an urbanized sub-basin and ecological risk assessment. Ecotoxicology 30(1):130\u2013141. https:\/\/doi.org\/10.1007\/s10646-020-02304-2","journal-title":"Ecotoxicology"},{"key":"36795_CR99","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.jgar.2023.05.010","volume":"34","author":"SS Sambaza","year":"2023","unstructured":"Sambaza SS, Naicker N (2023) Contribution of wastewater to antimicrobial resistance: a review article. J Glob Antimicrob Resist 34:23\u201329. https:\/\/doi.org\/10.1016\/j.jgar.2023.05.010","journal-title":"J Glob Antimicrob Resist"},{"key":"36795_CR100","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2024.123397","volume":"345","author":"MA Sandoval","year":"2024","unstructured":"Sandoval MA, Calzadilla W, Vidal J, Brillas E, Salazar-Gonz\u00e1lez R (2024) Contaminants of emerging concern: occurrence, analytical techniques, and removal with electrochemical advanced oxidation processes with special emphasis in Latin America. Environ Pollut 345. https:\/\/doi.org\/10.1016\/j.envpol.2024.123397","journal-title":"Environ Pollut"},{"key":"36795_CR101","doi-asserted-by":"publisher","unstructured":"Santos A V, Couto C F, Lebron Y A R, Moreira V R, Foureaux A F, Reis E O, Santos L V de S, Andrade L H, Amaral M C S & Lange L C. (2020). Occurrence and risk assessment of pharmaceutically active compounds in water supply systems in Brazil. Science of The Total Environment, 746, 141011. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141011","DOI":"10.1016\/j.scitotenv.2020.141011"},{"key":"36795_CR102","doi-asserted-by":"publisher","unstructured":"Sengar A and Vijayanandan A (2022). Human health and ecological risk assessment of 98 pharmaceuticals and personal care products (PPCPs) detected in Indian surface and wastewaters. Science of The Total Environment, 807(Part 1), 150677. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.150677","DOI":"10.1016\/j.scitotenv.2021.150677"},{"key":"36795_CR103","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2024.125383","volume":"365","author":"N Shahid","year":"2025","unstructured":"Shahid N, Iqbal HH, Ahmad SR, Qadir A, Krauss M, Finckh S, Tanui IC, Carmona E, Brack W (2025) Mixtures of toxic organic micropollutants compromise the safety of water resources in urban agglomerations in low- and medium-income countries: The example of Lahore. Pakistan Environmental Pollution 365. https:\/\/doi.org\/10.1016\/j.envpol.2024.125383","journal-title":"Pakistan Environmental Pollution"},{"issue":"12","key":"36795_CR104","doi-asserted-by":"publisher","first-page":"966","DOI":"10.3390\/toxics11120966","volume":"11","author":"M Shen","year":"2023","unstructured":"Shen M, Hu Y, Zhao K, Li C, Liu B, Li M, Lyu C, Sun L, Zhong S (2023) Occurrence, bioaccumulation, metabolism and ecotoxicity of fluoroquinolones in the aquatic environment: a review. Toxics 11(12):966. https:\/\/doi.org\/10.3390\/toxics11120966","journal-title":"Toxics"},{"key":"36795_CR105","unstructured":"Shihomatsu H M, Martins E A J, Cotrim M E B, Lebre D T & Pires M A F (2016). Avalia\u00e7\u00e3o da ocorr\u00eancia de f\u00e1rmacos nas \u00e1guas de represas do estado de S\u00e3o Paulo, SP, Brasil. In: XV Safety, Health and Environment World Congress. http:\/\/repositorio.ipen.br\/handle\/123456789\/25841. Accessed 10 October 2024."},{"issue":"1","key":"36795_CR106","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1590\/2318-08892016002800002","volume":"28","author":"OJG Sidone","year":"2016","unstructured":"Sidone OJG, Haddad EA, Mena-Chalco JP (2016) A ci\u00eancia nas regi\u00f5es brasileiras: evolu\u00e7\u00e3o da produ\u00e7\u00e3o e das redes de colabora\u00e7\u00e3o cient\u00edfica. Transinformacao 28(1):15\u201332. https:\/\/doi.org\/10.1590\/2318-08892016002800002","journal-title":"Transinformacao"},{"key":"36795_CR107","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1016\/j.scitotenv.2018.03.060","volume":"631\u2013632","author":"AJ Skees","year":"2018","unstructured":"Skees AJ, Foppe KS, Loganathan B, Subedi B (2018) Contamination profiles, mass loadings, and sewage epidemiology of neuropsychiatric and illicit drugs in wastewater and river waters from a community in the midwestern United States. Sci Total Environ 631\u2013632:1457\u20131464. https:\/\/doi.org\/10.1016\/j.scitotenv.2018.03.060","journal-title":"Sci Total Environ"},{"key":"36795_CR108","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.176314","volume":"954","author":"Y Soriano","year":"2024","unstructured":"Soriano Y, Carmona E, Renovell J, Pic\u00f3 Y, Brack W, Krauss M, Backhaus T, Inostroza PA (2024) Co-occurrence and spatial distribution of organic micropollutants in surface waters of the River Aconcagua and Maipo basins in Central Chile. Sci Total Environ 954. https:\/\/doi.org\/10.1016\/j.scitotenv.2024.176314","journal-title":"Sci Total Environ"},{"key":"36795_CR109","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/j.chemosphere.2018.06.046","volume":"209","author":"JCV Sposito","year":"2018","unstructured":"Sposito JCV, Montagner CC, Casado M, Navarro-Mart\u00edn L, Jut Sol\u00f3rzano JC, Pi\u00f1a B, Grisolia AB (2018) Emerging contaminants in Brazilian rivers: occurrence and effects on gene expression in zebrafish (Danio rerio) embryos. Chemosphere 209:696\u2013704. https:\/\/doi.org\/10.1016\/j.chemosphere.2018.06.046","journal-title":"Chemosphere"},{"key":"36795_CR110","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jhazmat.2018.04.043","volume":"372","author":"MCVM Starling","year":"2019","unstructured":"Starling MCVM, Amorim CC, Le\u00e3o MMD (2019) Occurrence, control and fate of contaminants of emerging concern in environmental compartments in Brazil. J Hazard Mater 372:17\u201336. https:\/\/doi.org\/10.1016\/j.jhazmat.2018.04.043","journal-title":"J Hazard Mater"},{"key":"36795_CR111","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.116133","volume":"269","author":"ME Vald\u00e9s","year":"2021","unstructured":"Vald\u00e9s ME, Santos LHMLM, Rodr\u00edguez Castro MC, Giorgi A, Barcel\u00f3 D, Rodr\u00edguez-Mozaz S, Am\u00e9 MV (2021) Distribution of antibiotics in water, sediments and biofilm in an urban river (C\u00f3rdoba, Argentina, LA). Environ Pollut 269. https:\/\/doi.org\/10.1016\/j.envpol.2020.116133","journal-title":"Environ Pollut"},{"key":"36795_CR112","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.168680","volume":"912","author":"M-A Vaudreuil","year":"2024","unstructured":"Vaudreuil M-A, Munoz G, Vo Duy S, Sauv\u00e9 S (2024) Tracking down pharmaceutical pollution in surface waters of the St. Lawrence River and its major tributaries. Sci Total Environ 912. https:\/\/doi.org\/10.1016\/j.scitotenv.2023.168680","journal-title":"Sci Total Environ"},{"key":"36795_CR113","doi-asserted-by":"publisher","unstructured":"Verma T, Bhaskarla C, Sadhir I, Sreedharan S & Nandi D (2018). Non-steroidal anti-inflammatory drugs, acetaminophen and ibuprofen, induce phenotypic antibiotic resistance in Escherichia coli: roles of marA and acrB. FEMS Microbiology Letters, 365(22). https:\/\/doi.org\/10.1093\/femsle\/fny251.","DOI":"10.1093\/femsle\/fny251"},{"issue":"Pt 2","key":"36795_CR114","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.156208","volume":"838","author":"M Veseli","year":"2022","unstructured":"Veseli M, Ro\u017eman M, Vilenica M, Petrovi\u0107 M, Previ\u0161i\u0107 A (2022) Bioaccumulation and bioamplification of pharmaceuticals and endocrine disruptors in aquatic insects. Sci Total Environ 838(Pt 2). https:\/\/doi.org\/10.1016\/j.scitotenv.2022.156208","journal-title":"Sci Total Environ"},{"issue":"2","key":"36795_CR115","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1038\/s41396-018-0275-x","volume":"13","author":"Y Wang","year":"2019","unstructured":"Wang Y, Lu J, Mao L, Li J, Yuan Z, Bond PL, Guo J (2019) Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera. International Society for Microbial Ecology 13(2):509\u2013522. https:\/\/doi.org\/10.1038\/s41396-018-0275-x","journal-title":"International Society for Microbial Ecology"},{"issue":"4","key":"36795_CR116","doi-asserted-by":"publisher","DOI":"10.1016\/j.xinn.2024.100612","volume":"5","author":"F Wang","year":"2024","unstructured":"Wang F, Xiang L, Leung KS-Y, Elsner M, Zhang Y, Guo Y, Pan B, Sun H, An T, Ying G, Brooks BW, Hou D, Helbling DE, Sun J, Qiu H, Vogel TM, Zhang W, Gao Y, Simpson MJ, Luo Y, Chang SX, Su G, Wong BM, Fu T-M, Zhu D, Jobst KJ, Ge C, Coulon F, Harindintwali JD, Zeng X, Wang H, Fu Y, Wei Z, Lohmann R, Chen C, Song Y, Sanchez-Cid C, Wang Y, El-Naggar A, Yao Y, Huang Y, Law JC-F, Gu C, Shen H, Gao Y, Qin C, Li H, Zhang T, Corcoll N, Liu M, Alessi DS, Li H, Brandt KK, Pico Y, Gu C, Guo J, Su J, Corvini P, Ye M, Rocha-Santos T, He H, Yang Y, Tong M, Zhang W, Suanon F, Brahushi F, Wang Z, Hashsham SA, Virta M, Yuan Q, Jiang G, Tremblay LA, Bu Q, Wu J, Peijnenburg W, Topp E, Cao X, Jiang X, Zheng M, Zhang T, Luo Y, Zhu L, Li X, Barcel\u00f3 D, Chen J, Xing B, Amelung W, Cai Z, Naidu R, Shen Q, Pawliszyn J, Zhu Y-G, Schaeffer A, Rillig MC, Wu F, Yu G, Tiedje JM (2024) Emerging contaminants: A One Health perspective. Innovation (Camb) 5(4). https:\/\/doi.org\/10.1016\/j.xinn.2024.100612","journal-title":"Innovation (Camb)"},{"issue":"2","key":"36795_CR117","doi-asserted-by":"publisher","DOI":"10.1128\/aem.01835-23","volume":"90","author":"DL Weller","year":"2024","unstructured":"Weller DL, Murphy CM, Love TMT, Danyluk MD, Strawn LK (2024) Methodological differences between studies confound one-size-fits-all approaches to managing surface waterways for food and water safety. Appl Environ Microbiol 90(2). https:\/\/doi.org\/10.1128\/aem.01835-23","journal-title":"Appl Environ Microbiol"},{"key":"36795_CR118","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.envpol.2016.12.026","volume":"222","author":"Z Xie","year":"2017","unstructured":"Xie Z, Lu G, Yan Z, Liu J, Wang P, Wang Y (2017) Bioaccumulation and trophic transfer of pharmaceuticals in food webs from a large freshwater lake. Environ Pollut 222:356\u2013366. https:\/\/doi.org\/10.1016\/j.envpol.2016.12.026","journal-title":"Environ Pollut"},{"key":"36795_CR119","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.136557","volume":"712","author":"L Zhang","year":"2020","unstructured":"Zhang L, Qin S, Shen L, Li S, Cui J, Liu Y (2020) Bioaccumulation, trophic transfer, and human health risk of quinolones antibiotics in the benthic food web from a macrophyte-dominated shallow lake, North China. Sci Total Environ 712. https:\/\/doi.org\/10.1016\/j.scitotenv.2020.136557","journal-title":"Sci Total Environ"},{"key":"36795_CR120","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2024.122165","volume":"263","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Guo C, Wu R, Hou S, Liu Y, Zhao J, Jiang M, Xu J, Wu F (2024) Global occurrence, distribution, and ecological risk assessment of psychopharmaceuticals and illicit drugs in surface water environment: a meta-analysis. Water Res 263. https:\/\/doi.org\/10.1016\/j.watres.2024.122165","journal-title":"Water Res"},{"key":"36795_CR121","doi-asserted-by":"publisher","unstructured":"Zhang Y, Huang G, Zhang Q, Bi X, Chu H, Liu Z, Luo J, Bai S, Mo S, Wang H & Fu M. (2024). Occurrence, distribution, and ecological risk assessment of pharmaceuticals and personal care products in the surface water of Lipu River, China. Environmental Research, 252(Part 2), 118908. https:\/\/doi.org\/10.1016\/j.envres.2024.118908.","DOI":"10.1016\/j.envres.2024.118908"},{"issue":"3","key":"36795_CR122","doi-asserted-by":"publisher","first-page":"351","DOI":"10.2166\/wh.2021.264","volume":"19","author":"LB Zini","year":"2021","unstructured":"Zini LB, Gutterres M (2021) Chemical contaminants in Brazilian drinking water: a systematic review. J Water Health 19(3):351\u2013369. https:\/\/doi.org\/10.2166\/wh.2021.264","journal-title":"J Water Health"}],"container-title":["Environmental Science and Pollution Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-025-36795-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11356-025-36795-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11356-025-36795-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T08:46:36Z","timestamp":1758098796000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11356-025-36795-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,27]]},"references-count":122,"journal-issue":{"issue":"35","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["36795"],"URL":"https:\/\/doi.org\/10.1007\/s11356-025-36795-5","relation":{},"ISSN":["1614-7499"],"issn-type":[{"value":"1614-7499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,27]]},"assertion":[{"value":"18 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This is not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"This is not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Ethical approval"}},{"value":"This is not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"This is not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The amendments include the addition of two co-authors, Eduarda Talita Bramorski Mohr and Izadora Borgmann Frizzo, and the date of completion of the article.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Amendments to the information provided in the protocol"}}]}}