{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:30:51Z","timestamp":1791293451784,"version":"4.1.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["GeroScience"],"DOI":"10.1007\/s11357-024-01435-2","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T09:32:07Z","timestamp":1732786327000},"page":"1303-1318","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Associations between MASLD, atrial fibrillation, cardiovascular events, mortality and aspirin use in older adults"],"prefix":"10.1007","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7479-9669","authenticated-orcid":false,"given":"Daniel","family":"Clayton-Chubb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart K.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar","family":"Majeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn L.","family":"Woods","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Tonkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew T.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cammie","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hodge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Lubel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans G.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Brodtmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharyn M.","family":"Fitzgerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne G.","family":"Orchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"McNeil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Kemp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"issue":"3","key":"1435_CR1","doi-asserted-by":"publisher","first-page":"687","DOI":"10.3390\/nu15030687","volume":"15","author":"D Clayton-Chubb","year":"2023","unstructured":"Clayton-Chubb D, Kemp W, Majeed A, et al. Understanding NAFLD: from case identification to interventions, outcomes, and future perspectives. Nutrients. 2023;15(3):687.","journal-title":"Nutrients"},{"key":"1435_CR2","doi-asserted-by":"publisher","first-page":"E93","DOI":"10.1016\/j.jhep.2023.06.003","volume":"79","author":"ME Rinella","year":"2023","unstructured":"Rinella ME, Lazarus JV, Ratziu V, et al. A multi-society Delphi consensus statement on new fatty liver disease nomenclature. J Hepatol. 2023;79:E93\u20134.","journal-title":"J Hepatol"},{"issue":"11","key":"1435_CR3","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/S2468-1253(21)00308-3","volume":"6","author":"A Mantovani","year":"2021","unstructured":"Mantovani A, Csermely A, Petracca G, et al. Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2021;6(11):903\u201313.","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"1435_CR4","doi-asserted-by":"publisher","unstructured":"Driessen S, Francque SM, Anker SD, et al. Metabolic dysfunction-associated steatotic liver disease and the heart. Hepatology. 2023. https:\/\/doi.org\/10.1097\/HEP.0000000000000735.","DOI":"10.1097\/HEP.0000000000000735"},{"issue":"4","key":"1435_CR5","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1111\/liv.14044","volume":"39","author":"A Mantovani","year":"2019","unstructured":"Mantovani A, Dauriz M, Sandri D, et al. Association between non-alcoholic fatty liver disease and risk of atrial fibrillation in adult individuals: an updated meta-analysis. Liver Int. 2019;39(4):758\u201369.","journal-title":"Liver Int"},{"issue":"1","key":"1435_CR6","doi-asserted-by":"publisher","first-page":"11124","DOI":"10.1038\/s41598-019-47687-3","volume":"9","author":"Y Liu","year":"2019","unstructured":"Liu Y, Zhong GC, Tan HY, et al. Nonalcoholic fatty liver disease and mortality from all causes, cardiovascular disease, and cancer: a meta-analysis. Sci Rep. 2019;9(1):11124.","journal-title":"Sci Rep"},{"issue":"3","key":"1435_CR7","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1136\/gutjnl-2019-318813","volume":"69","author":"ZM Younossi","year":"2020","unstructured":"Younossi ZM, Stepanova M, Younossi Y, et al. Epidemiology of chronic liver diseases in the USA in the past three decades. Gut. 2020;69(3):564\u20138.","journal-title":"Gut"},{"issue":"1","key":"1435_CR8","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1002\/hep.29466","volume":"67","author":"C Estes","year":"2018","unstructured":"Estes C, Razavi H, Loomba R, et al. Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease. Hepatology. 2018;67(1):123\u201333.","journal-title":"Hepatology"},{"key":"1435_CR9","unstructured":"United Nations, Department of Economic and Social Affairs, Population Division. World Population Ageing 2019 (ST\/ESA\/SER. A\/444). 2020."},{"issue":"7","key":"1435_CR10","first-page":"e9349","volume":"12","author":"MA Khan","year":"2020","unstructured":"Khan MA, Hashim MJ, Mustafa H, et al. Global epidemiology of ischemic heart disease: results from the global burden of disease study. Cureus. 2020;12(7):e9349.","journal-title":"Cureus"},{"issue":"2","key":"1435_CR11","doi-asserted-by":"publisher","first-page":"169","DOI":"10.2991\/jegh.k.201217.001","volume":"11","author":"U Ralapanawa","year":"2021","unstructured":"Ralapanawa U, Sivakanesan R. Epidemiology and the magnitude of coronary artery disease and acute coronary syndrome: a narrative review. J Epidemiol Glob Health. 2021;11(2):169\u201377.","journal-title":"J Epidemiol Glob Health"},{"issue":"16","key":"1435_CR12","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/j.jacc.2013.01.054","volume":"61","author":"N Savji","year":"2013","unstructured":"Savji N, Rockman CB, Skolnick AH, et al. Association between advanced age and vascular disease in different arterial territories: a population database of over 3.6 million subjects. J Am Coll Cardiol. 2013;61(16):1736\u201343.","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"1435_CR13","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1161\/CIRCRESAHA.117.309732","volume":"120","author":"L Staerk","year":"2017","unstructured":"Staerk L, Sherer JA, Ko D, et al. Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes. Circ Res. 2017;120(9):1501\u201317.","journal-title":"Circ Res"},{"issue":"9","key":"1435_CR14","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1136\/gutjnl-2020-320622","volume":"69","author":"G Targher","year":"2020","unstructured":"Targher G, Byrne CD, Tilg H. NAFLD and increased risk of cardiovascular disease: clinical associations, pathophysiological mechanisms and pharmacological implications. Gut. 2020;69(9):1691\u2013705.","journal-title":"Gut"},{"issue":"5","key":"1435_CR15","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1002\/hep.32519","volume":"76","author":"Y Shang","year":"2022","unstructured":"Shang Y, Nasr P, Widman L, et al. Risk of cardiovascular disease and loss in life expectancy in NAFLD. Hepatology. 2022;76(5):1495\u2013505.","journal-title":"Hepatology"},{"issue":"2","key":"1435_CR16","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1002\/hep.32635","volume":"77","author":"LA van Kleef","year":"2023","unstructured":"van Kleef LA, Sonneveld MJ, Kavousi M, et al. Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study. Hepatology. 2023;77(2):585\u201393.","journal-title":"Hepatology"},{"issue":"1","key":"1435_CR17","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12876-019-0972-6","volume":"19","author":"P Golabi","year":"2019","unstructured":"Golabi P, Paik J, Reddy R, et al. Prevalence and long-term outcomes of non-alcoholic fatty liver disease among elderly individuals from the United States. BMC Gastroenterol. 2019;19(1):56.","journal-title":"BMC Gastroenterol"},{"issue":"1","key":"1435_CR18","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1136\/gutjnl-2020-323082","volume":"71","author":"A Mantovani","year":"2022","unstructured":"Mantovani A, Petracca G, Beatrice G, et al. Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis. Gut. 2022;71(1):156\u201362.","journal-title":"Gut"},{"issue":"5","key":"1435_CR19","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1136\/gutjnl-2020-322572","volume":"70","author":"A Mantovani","year":"2021","unstructured":"Mantovani A, Petracca G, Beatrice G, et al. Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals. Gut. 2021;70(5):962\u20139.","journal-title":"Gut"},{"issue":"2","key":"1435_CR20","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1161\/HYPERTENSIONAHA.119.13419","volume":"75","author":"YC Zhao","year":"2020","unstructured":"Zhao YC, Zhao GJ, Chen Z, et al. Nonalcoholic fatty liver disease: an emerging driver of hypertension. Hypertension. 2020;75(2):275\u201384.","journal-title":"Hypertension"},{"key":"1435_CR21","doi-asserted-by":"publisher","first-page":"173124","DOI":"10.1155\/2012\/173124","volume":"2012","author":"EV Paez Espinosa","year":"2012","unstructured":"Paez Espinosa EV, Murad JP, Khasawneh FT. Aspirin: pharmacology and clinical applications. Thrombosis. 2012;2012:173124.","journal-title":"Thrombosis"},{"issue":"34","key":"1435_CR22","doi-asserted-by":"publisher","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","volume":"42","author":"FLJ Visseren","year":"2021","unstructured":"Visseren FLJ, Mach F, Smulders YM, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42(34):3227\u2013337.","journal-title":"Eur Heart J"},{"issue":"11","key":"1435_CR23","first-page":"e596","volume":"140","author":"DK Arnett","year":"2019","unstructured":"Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC\/AHA Guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology\/American Heart Association Task Force on clinical practice guidelines. Circulation. 2019;140(11):e596\u2013646.","journal-title":"Circulation"},{"issue":"16","key":"1435_CR24","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1056\/NEJMoa1805819","volume":"379","author":"JJ McNeil","year":"2018","unstructured":"McNeil JJ, Wolfe R, Woods RL, et al. Effect of aspirin on cardiovascular events and bleeding in the healthy elderly. N Engl J Med. 2018;379(16):1509\u201318.","journal-title":"N Engl J Med"},{"issue":"16","key":"1435_CR25","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1056\/NEJMoa1803955","volume":"379","author":"JJ McNeil","year":"2018","unstructured":"McNeil JJ, Nelson MR, Woods RL, et al. Effect of aspirin on all-cause mortality in the healthy elderly. N Engl J Med. 2018;379(16):1519\u201328.","journal-title":"N Engl J Med"},{"issue":"6","key":"1435_CR26","doi-asserted-by":"publisher","first-page":"e168","DOI":"10.1161\/ATV.0000000000000153","volume":"42","author":"PB Duell","year":"2022","unstructured":"Duell PB, Welty FK, Miller M, et al. Nonalcoholic fatty liver disease and cardiovascular risk: a scientific statement from the American heart association. Arterioscler Thromb Vasc Biol. 2022;42(6):e168\u201385.","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"1435_CR27","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1111\/apt.15192","volume":"49","author":"RD Abeles","year":"2019","unstructured":"Abeles RD, Mullish BH, Forlano R, et al. Derivation and validation of a cardiovascular risk score for prediction of major acute cardiovascular events in non-alcoholic fatty liver disease; the importance of an elevated mean platelet volume. Aliment Pharmacol Ther. 2019;49(8):1077\u201385.","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"1435_CR28","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/apt.12998","volume":"41","author":"MJ Armstrong","year":"2015","unstructured":"Armstrong MJ, Rowe IA. Editorial: would an aspirin a day keep NAFLD and its complications away? Aliment Pharmacol Ther. 2015;41(1):145.","journal-title":"Aliment Pharmacol Ther"},{"issue":"2","key":"1435_CR29","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.cct.2013.09.014","volume":"36","author":"Aspree Investigator Group","year":"2013","unstructured":"Aspree Investigator Group. Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial. Contemp Clin Trials. 2013;36(2):555\u201364.","journal-title":"Contemp Clin Trials"},{"issue":"11","key":"1435_CR30","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1093\/gerona\/glw342","volume":"72","author":"JJ McNeil","year":"2017","unstructured":"McNeil JJ, Woods RL, Nelson MR, et al. Baseline characteristics of participants in the ASPREE (ASPirin in Reducing Events in the Elderly) study. J Gerontol A Biol Sci Med Sci. 2017;72(11):1586\u201393.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"1435_CR31","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-230X-6-33","volume":"6","author":"G Bedogni","year":"2006","unstructured":"Bedogni G, Bellentani S, Miglioli L, et al. The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterol. 2006;6:33.","journal-title":"BMC Gastroenterol"},{"issue":"1","key":"1435_CR32","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1111\/liv.15725","volume":"44","author":"D Clayton-Chubb","year":"2024","unstructured":"Clayton-Chubb D, Kemp WW, Majeed A, et al. Metabolic dysfunction-associated steatotic liver disease in older adults is associated with frailty and social disadvantage. Liver Int. 2024;44(1):39\u201351. https:\/\/doi.org\/10.1111\/liv.15725.","journal-title":"Liver Int."},{"issue":"2","key":"1435_CR33","doi-asserted-by":"publisher","first-page":"e76","DOI":"10.1016\/j.jhep.2023.08.026","volume":"80","author":"H Hagstrom","year":"2024","unstructured":"Hagstrom H, Vessby J, Ekstedt M, et al. 99% of patients with NAFLD meet MASLD criteria and natural history is therefore identical. J Hepatol. 2024;80(2):e76\u20137. https:\/\/doi.org\/10.1016\/j.jhep.2023.08.026.","journal-title":"J Hepatol."},{"issue":"1","key":"1435_CR34","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.29367","volume":"67","author":"N Chalasani","year":"2018","unstructured":"Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2018;67(1):328\u201357.","journal-title":"Hepatology"},{"issue":"1","key":"1435_CR35","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.jhep.2020.03.039","volume":"73","author":"M Eslam","year":"2020","unstructured":"Eslam M, Newsome PN, Sarin SK, et al. A new definition for metabolic dysfunction-associated fatty liver disease: an international expert consensus statement. J Hepatol. 2020;73(1):202\u20139.","journal-title":"J Hepatol"},{"issue":"5","key":"1435_CR36","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1111\/j.1464-5491.2006.01858.x","volume":"23","author":"KG Alberti","year":"2006","unstructured":"Alberti KG, Zimmet P, Shaw J. Metabolic syndrome\u2013a new world-wide definition. a consensus statement from the international diabetes federation. Diabet Med. 2006;23(5):469\u201380.","journal-title":"Diabet Med"},{"issue":"33","key":"1435_CR37","doi-asserted-by":"publisher","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","volume":"39","author":"B Williams","year":"2018","unstructured":"Williams B, Mancia G, Spiering W, et al. 2018 ESC\/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39(33):3021\u2013104.","journal-title":"Eur Heart J"},{"issue":"8","key":"1435_CR38","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1001\/jama.2021.12531","volume":"326","author":"KW Davidson","year":"2021","unstructured":"US Preventive Services Task Force, Davidson KW, Barry MJ, et al. Screening for prediabetes and type 2 diabetes: us preventive services task force recommendation statement. JAMA. 2021;326(8):736\u201343.","journal-title":"JAMA"},{"issue":"4","key":"1435_CR39","doi-asserted-by":"publisher","first-page":"224","DOI":"10.5694\/mja11.11468","volume":"197","author":"DW Johnson","year":"2012","unstructured":"Johnson DW, Jones GR, Mathew TH, et al. Chronic kidney disease and measurement of albuminuria or proteinuria: a position statement. Med J Aust. 2012;197(4):224\u20135.","journal-title":"Med J Aust"},{"key":"1435_CR40","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1093\/ehjcvp\/pvad082","volume":"10","author":"J Ball","year":"2023","unstructured":"Ball J, Neumann JT, Tonkin AM, et al. Low-dose aspirin and incident atrial fibrillation in healthy older individuals: a post-hoc analysis of the ASPREE trial. Eur Heart J Cardiovasc Pharmacother. 2023;10:81\u20132.","journal-title":"Eur Heart J Cardiovasc Pharmacother"},{"issue":"1","key":"1435_CR41","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/s11357-021-00486-z","volume":"44","author":"JT Neumann","year":"2022","unstructured":"Neumann JT, Thao LTP, Callander E, et al. Cardiovascular risk prediction in healthy older people. Geroscience. 2022;44(1):403\u201313.","journal-title":"Geroscience"},{"issue":"1","key":"1435_CR42","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/hep.28431","volume":"64","author":"ZM Younossi","year":"2016","unstructured":"Younossi ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73\u201384.","journal-title":"Hepatology"},{"issue":"5","key":"1435_CR43","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1053\/j.gastro.2021.07.049","volume":"161","author":"F Kanwal","year":"2021","unstructured":"Kanwal F, Shubrook JH, Adams LA, et al. Clinical care pathway for the risk stratification and management of patients with nonalcoholic fatty liver disease. Gastroenterology. 2021;161(5):1657\u201369.","journal-title":"Gastroenterology"},{"issue":"6","key":"1435_CR44","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/j.jhep.2015.11.004","volume":"64","author":"European Association for the Study of the Liver, European Association for the Study of Diabetes, European Association for the Study of Obesity","year":"2016","unstructured":"European Association for the Study of the Liver, European Association for the Study of Diabetes, European Association for the Study of Obesity. EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016;64(6):1388\u2013402.","journal-title":"J Hepatol"},{"issue":"5","key":"1435_CR45","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1002\/hep.27368","volume":"61","author":"M Ekstedt","year":"2015","unstructured":"Ekstedt M, Hagstrom H, Nasr P, et al. Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology. 2015;61(5):1547\u201354.","journal-title":"Hepatology"},{"issue":"25","key":"1435_CR46","doi-asserted-by":"publisher","first-page":"2439","DOI":"10.1093\/eurheartj\/ehab309","volume":"42","author":"SCORE2 Working Group and ESC Cardiovascular Risk Collaboration","year":"2021","unstructured":"SCORE2 Working Group and ESC Cardiovascular Risk Collaboration. SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. Eur Heart J. 2021;42(25):2439\u201354.","journal-title":"Eur Heart J"},{"key":"1435_CR47","doi-asserted-by":"publisher","first-page":"102065","DOI":"10.1016\/j.eclinm.2023.102065","volume":"61","author":"TY Lee","year":"2023","unstructured":"Lee TY, Hsu YC, Ho HJ, et al. Daily aspirin associated with a reduced risk of hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: a population-based cohort study. EClinicalMedicine. 2023;61:102065.","journal-title":"EClinicalMedicine"},{"issue":"13","key":"1435_CR48","doi-asserted-by":"publisher","first-page":"2776","DOI":"10.1016\/j.cgh.2019.04.061","volume":"17","author":"TG Simon","year":"2019","unstructured":"Simon TG, Henson J, Osganian S, et al. Daily aspirin use associated with reduced risk for fibrosis progression in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2019;17(13):2776-84 e4.","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"11","key":"1435_CR49","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1001\/jama.2024.1215","volume":"331","author":"TG Simon","year":"2024","unstructured":"Simon TG, Wilechansky RM, Stoyanova S, et al. Aspirin for metabolic dysfunction-associated steatotic liver disease without cirrhosis: a randomized clinical trial. JAMA. 2024;331(11):920\u20139.","journal-title":"JAMA"},{"key":"1435_CR50","doi-asserted-by":"publisher","first-page":"7806860","DOI":"10.1155\/2020\/7806860","volume":"2020","author":"YM Han","year":"2020","unstructured":"Han YM, Lee YJ, Jang YN, et al. Aspirin improves nonalcoholic fatty liver disease and atherosclerosis through regulation of the PPARdelta-AMPK-PGC-1alpha pathway in dyslipidemic conditions. Biomed Res Int. 2020;2020:7806860.","journal-title":"Biomed Res Int"},{"issue":"17","key":"1435_CR51","first-page":"1294","volume":"38","author":"CX Wong","year":"2017","unstructured":"Wong CX, Ganesan AN, Selvanayagam JB. Epicardial fat and atrial fibrillation: current evidence, potential mechanisms, clinical implications, and future directions. Eur Heart J. 2017;38(17):1294\u2013302.","journal-title":"Eur Heart J"},{"issue":"11","key":"1435_CR52","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1161\/CIRCRESAHA.121.319059","volume":"128","author":"Z Chen","year":"2021","unstructured":"Chen Z, Liu J, Zhou F, et al. Nonalcoholic fatty liver disease: an emerging driver of cardiac arrhythmia. Circ Res. 2021;128(11):1747\u201365.","journal-title":"Circ Res"},{"issue":"4","key":"1435_CR53","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/j.jhep.2022.05.030","volume":"77","author":"LA van Kleef","year":"2022","unstructured":"van Kleef LA, Lu Z, Ikram MA, et al. Liver stiffness not fatty liver disease is associated with atrial fibrillation: The Rotterdam study. J Hepatol. 2022;77(4):931\u20138.","journal-title":"J Hepatol"},{"issue":"9","key":"1435_CR54","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/j.cgh.2012.12.031","volume":"11","author":"EM Koehler","year":"2013","unstructured":"Koehler EM, Schouten JN, Hansen BE, et al. External validation of the fatty liver index for identifying nonalcoholic fatty liver disease in a population-based study. Clin Gastroenterol Hepatol. 2013;11(9):1201\u20134.","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["GeroScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-024-01435-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11357-024-01435-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-024-01435-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T14:21:52Z","timestamp":1741011712000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11357-024-01435-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,28]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["1435"],"URL":"https:\/\/doi.org\/10.1007\/s11357-024-01435-2","relation":{},"ISSN":["2509-2723"],"issn-type":[{"value":"2509-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,28]]},"assertion":[{"value":"15 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}