{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:43:33Z","timestamp":1792035813272,"version":"4.4.0"},"reference-count":176,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002332","name":"Semmelweis University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002332","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["GeroScience"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Age-related cognitive impairment and dementia pose a significant global health, social, and economic challenge. While Alzheimer\u2019s disease (AD) has historically been viewed as the leading cause of dementia, recent evidence reveals the considerable impact of vascular cognitive impairment and dementia (VCID), which now accounts for nearly half of all dementia cases. The Mediterranean diet\u2014characterized by high consumption of fruits, vegetables, whole grains, fish, and olive oil\u2014has been widely recognized for its cardiovascular benefits and may also reduce the risk of cognitive decline and dementia. To investigate the protective effects of the Mediterranean diet on cognitive health, we conducted a systematic literature review using PubMed, Web of Science, and Google Scholar, focusing on studies published between 2000 and 2024. The studies included in the meta-nalysis examined the adherence to the Mediterranean diet and the incidence of dementia and AD. We applied a random-effects model to calculate pooled hazard ratios (HRs) with 95% confidence intervals (CIs) and assessed heterogeneity through\n                    <jats:italic>I<\/jats:italic>\n                    -square statistics. Forest plots, funnel plots, and\n                    <jats:italic>Z<\/jats:italic>\n                    -score plots were used to visualize study outcomes. Of the 324 full-text records reviewed, 23 studies met the inclusion criteria. The combined HR for cognitive impairment among those adhering to the Mediterranean diet was 0.82 (95% CI 0.75\u20130.89); for dementia, the HR was 0.89 (95% CI 0.83\u20130.95); and for AD, the HR was 0.70 (95% CI 0.60\u20130.82), indicating substantial protective effects. Significant heterogeneity was observed across studies, though\n                    <jats:italic>Z<\/jats:italic>\n                    -score plots suggested sufficient sample sizes to support reliable conclusions for each condition. In conclusion, this meta-analysis confirms that adherence to the Mediterranean diet is associated with an 11\u201330% reduction in the risk of age-related cognitive disorders, including cognitive impairment, dementia, and AD. These findings underscore the Mediterranean diet\u2019s potential as a central element in neuroprotective public health strategies to mitigate the global impact of cognitive decline and dementia and to promote healthier cognitive aging.\n                  <\/jats:p>","DOI":"10.1007\/s11357-024-01488-3","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T03:10:20Z","timestamp":1736565020000},"page":"3111-3130","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":149,"title":["The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer\u2019s disease: a meta-analysis"],"prefix":"10.1007","volume":"47","author":[{"given":"M\u00f3nika","family":"Fekete","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Varga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan","family":"Ungvari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1nos Tibor","family":"Fekete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Buda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1gnes","family":"Szappanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Lehoczki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mi","family":"M\u00f3zes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Grosso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justyna","family":"Godos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otilia","family":"Menyhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u00f6ngyi","family":"Munk\u00e1csy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Tarantini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andriy","family":"Yabluchanskiy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5053-2828","authenticated-orcid":false,"given":"Anna","family":"Ungvari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bal\u00e1zs","family":"Gy\u0151rffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"issue":"7","key":"1488_CR1","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1016\/S2468-2667(21)00249-8","volume":"2022","author":"GBD","year":"2019","unstructured":"GBD. Dementia Forecasting Collaborators: Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2019;2022(7):e105\u201325. https:\/\/doi.org\/10.1016\/S2468-2667(21)00249-8.","journal-title":"Lancet Public Health"},{"key":"1488_CR2","doi-asserted-by":"publisher","unstructured":"2024 Alzheimer\u2019s disease facts and figures. Alzheimers Dement. 2024;20:3708-3821. https:\/\/doi.org\/10.1002\/alz.13809","DOI":"10.1002\/alz.13809"},{"key":"1488_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-024-01180-6","author":"X Cao","year":"2024","unstructured":"Cao X, Wang M, Zhou M, Mi Y, Fazekas-Pongor V, Major D, Lehoczki A, Guo Y. Trends in prevalence, mortality, and risk factors of dementia among the oldest-old adults in the United States: the role of the obesity epidemic. Geroscience. 2024. https:\/\/doi.org\/10.1007\/s11357-024-01180-6.","journal-title":"Geroscience"},{"key":"1488_CR4","doi-asserted-by":"publisher","first-page":"709156","DOI":"10.3389\/fnagi.2021.709156","volume":"13","author":"Y Gao","year":"2021","unstructured":"Gao Y, Liu X. Secular trends in the incidence of and mortality due to Alzheimer\u2019s disease and other forms of dementia in China From 1990 to 2019: an age-period-cohort study and joinpoint analysis. Front Aging Neurosci. 2021;13:709156. https:\/\/doi.org\/10.3389\/fnagi.2021.709156.","journal-title":"Front Aging Neurosci"},{"key":"1488_CR5","first-page":"1589","volume":"322","author":"Z Arvanitakis","year":"2019","unstructured":"Arvanitakis Z, Shah RC, Bennett DA. Diagnosis and management of dementia Jama. 2019;322:1589\u201399.","journal-title":"Diagnosis and management of dementia Jama"},{"key":"1488_CR6","doi-asserted-by":"publisher","first-page":"3326","DOI":"10.1016\/j.jacc.2019.04.034","volume":"73","author":"C Iadecola","year":"2019","unstructured":"Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia: JACC Scientific Expert Panel. J Am Coll Cardiol. 2019;73:3326\u201344. https:\/\/doi.org\/10.1016\/j.jacc.2019.04.034.","journal-title":"J Am Coll Cardiol"},{"key":"1488_CR7","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.bbadis.2015.12.015","volume":"1862","author":"PB Gorelick","year":"2016","unstructured":"Gorelick PB, Counts SE, Nyenhuis D. Vascular cognitive impairment and dementia. Biochim Biophys Acta. 2016;1862:860\u20138. https:\/\/doi.org\/10.1016\/j.bbadis.2015.12.015.","journal-title":"Biochim Biophys Acta"},{"key":"1488_CR8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1161\/CIRCRESAHA.116.308426","volume":"120","author":"M Dichgans","year":"2017","unstructured":"Dichgans M, Leys D. Vascular cognitive impairment. Circ Res. 2017;120:573\u201391. https:\/\/doi.org\/10.1161\/CIRCRESAHA.116.308426.","journal-title":"Circ Res"},{"key":"1488_CR9","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.trsl.2022.12.003","volume":"254","author":"LB Eisenmenger","year":"2023","unstructured":"Eisenmenger LB, Peret A, Famakin BM, Spahic A, Roberts GS, Bockholt JH, Johnson KM, Paulsen JS. Vascular contributions to Alzheimer\u2019s disease. Transl Res. 2023;254:41\u201353. https:\/\/doi.org\/10.1016\/j.trsl.2022.12.003.","journal-title":"Transl Res"},{"key":"1488_CR10","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1016\/j.jacc.2019.10.062","volume":"75","author":"M Cortes-Canteli","year":"2020","unstructured":"Cortes-Canteli M, Iadecola C. Alzheimer\u2019s disease and vascular aging: JACC focus seminar. J Am Coll Cardiol. 2020;75:942\u201351. https:\/\/doi.org\/10.1016\/j.jacc.2019.10.062.","journal-title":"J Am Coll Cardiol"},{"key":"1488_CR11","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12868-018-0465-5","volume":"19","author":"O Shabir","year":"2018","unstructured":"Shabir O, Berwick J, Francis SE. Neurovascular dysfunction in vascular dementia. Alzheimer\u2019s Atheroscler BMC Neurosci. 2018;19:62. https:\/\/doi.org\/10.1186\/s12868-018-0465-5.","journal-title":"Alzheimer\u2019s Atheroscler BMC Neurosci"},{"key":"1488_CR12","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1038\/s41593-018-0234-x","volume":"21","author":"MD Sweeney","year":"2018","unstructured":"Sweeney MD, Kisler K, Montagne A, Toga AW, Zlokovic BV. The role of brain vasculature in neurodegenerative disorders. Nat Neurosci. 2018;21:1318\u201331. https:\/\/doi.org\/10.1038\/s41593-018-0234-x.","journal-title":"Nat Neurosci"},{"key":"1488_CR13","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nrneurol.2017.188","volume":"14","author":"MD Sweeney","year":"2018","unstructured":"Sweeney MD, Sagare AP, Zlokovic BV. Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders. Nat Rev Neurol. 2018;14:133\u201350. https:\/\/doi.org\/10.1038\/nrneurol.2017.188.","journal-title":"Nat Rev Neurol"},{"key":"1488_CR14","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1152\/physrev.00050.2017","volume":"99","author":"MD Sweeney","year":"2019","unstructured":"Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. Blood-brain barrier: from physiology to disease and back. Physiol Rev. 2019;99:21\u201378. https:\/\/doi.org\/10.1152\/physrev.00050.2017.","journal-title":"Physiol Rev"},{"key":"1488_CR15","doi-asserted-by":"publisher","first-page":"H1","DOI":"10.1152\/ajpheart.00581.2016","volume":"312","author":"P Toth","year":"2017","unstructured":"Toth P, Tarantini S, Csiszar A, Ungvari Z. Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging. Am J Physiol Heart Circ Physiol. 2017;312:H1\u201320. https:\/\/doi.org\/10.1152\/ajpheart.00581.2016.","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"1488_CR16","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1161\/STROKEAHA.121.036140","volume":"53","author":"DA Levine","year":"2022","unstructured":"Levine DA, Springer MV, Brodtmann A. Blood pressure and vascular cognitive impairment. Stroke. 2022;53:1104\u201313. https:\/\/doi.org\/10.1161\/STROKEAHA.121.036140.","journal-title":"Stroke"},{"key":"1488_CR17","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1161\/CIRCRESAHA.118.313260","volume":"124","author":"C Iadecola","year":"2019","unstructured":"Iadecola C, Gottesman RF. Neurovascular and cognitive dysfunction in hypertension. Circ Res. 2019;124:1025\u201344. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.313260.","journal-title":"Circ Res"},{"key":"1488_CR18","doi-asserted-by":"publisher","first-page":"H740","DOI":"10.1152\/ajpheart.00736.2020","volume":"320","author":"P Balasubramanian","year":"2021","unstructured":"Balasubramanian P, Kiss T, Tarantini S, Nyul-Toth A, Ahire C, Yabluchanskiy A, Csipo T, Lipecz A, Tabak A, Institoris A, Csiszar A, Ungvari Z. Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021;320:H740\u201361. https:\/\/doi.org\/10.1152\/ajpheart.00736.2020.","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"1488_CR19","doi-asserted-by":"publisher","unstructured":"Robison LS, Albert NM, Camargo LA, Anderson BM, Salinero AE, Riccio DA, Abi-Ghanem C, Gannon OJ, Zuloaga KL. High-fat diet-induced obesity causes sex-specific deficits in adult hippocampal neurogenesis in mice. eNeuro. 2020;7. https:\/\/doi.org\/10.1523\/ENEURO.0391-19.2019","DOI":"10.1523\/ENEURO.0391-19.2019"},{"key":"1488_CR20","doi-asserted-by":"publisher","first-page":"827","DOI":"10.3233\/JAD-200392","volume":"78","author":"EA Hu","year":"2020","unstructured":"Hu EA, Wu A, Dearborn JL, Gottesman RF, Sharrett AR, Steffen LM, Coresh J, Rebholz CM. Adherence to dietary patterns and risk of incident dementia: findings from the atherosclerosis risk in communities study. J Alzheimers Dis. 2020;78:827\u201335. https:\/\/doi.org\/10.3233\/JAD-200392.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR21","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1001\/jamaneurol.2017.1658","volume":"74","author":"RF Gottesman","year":"2017","unstructured":"Gottesman RF, Albert MS, Alonso A, Coker LH, Coresh J, Davis SM, Deal JA, McKhann GM, Mosley TH, Sharrett AR, Schneider ALC, Windham BG, Wruck LM, Knopman DS. Associations between midlife vascular risk factors and 25-year incident dementia in the Atherosclerosis Risk in Communities (ARIC) cohort. JAMA Neurol. 2017;74:1246\u201354. https:\/\/doi.org\/10.1001\/jamaneurol.2017.1658.","journal-title":"JAMA Neurol"},{"key":"1488_CR22","doi-asserted-by":"publisher","first-page":"E51","DOI":"10.1002\/oby.20037","volume":"21","author":"M Loef","year":"2013","unstructured":"Loef M, Walach H. Midlife obesity and dementia: meta-analysis and adjusted forecast of dementia prevalence in the United States and China. Obesity (Silver Spring). 2013;21:E51-55. https:\/\/doi.org\/10.1002\/oby.20037.","journal-title":"Obesity (Silver Spring)"},{"key":"1488_CR23","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1038\/ijo.2012.37","volume":"37","author":"AK Dahl","year":"2013","unstructured":"Dahl AK, Hassing LB, Fransson EI, Gatz M, Reynolds CA, Pedersen NL. Body mass index across midlife and cognitive change in late life. Int J Obes (Lond). 2013;37:296\u2013302. https:\/\/doi.org\/10.1038\/ijo.2012.37.","journal-title":"Int J Obes (Lond)"},{"key":"1488_CR24","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1093\/epirev\/mxs002","volume":"35","author":"AK Dahl","year":"2013","unstructured":"Dahl AK, Hassing LB. Obesity and cognitive aging. Epidemiol Rev. 2013;35:22\u201332. https:\/\/doi.org\/10.1093\/epirev\/mxs002.","journal-title":"Epidemiol Rev"},{"key":"1488_CR25","doi-asserted-by":"publisher","unstructured":"Ryan CM, van Duinkerken E, Rosano C. Neurocognitive consequences of diabetes. Am Psychol. 2016;71:563\u2013576. 2016\u201347119\u2013005 [pii]. https:\/\/doi.org\/10.1037\/a0040455.","DOI":"10.1037\/a0040455"},{"key":"1488_CR26","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/S2213-8587(13)70192-X","volume":"2","author":"RH Tuligenga","year":"2014","unstructured":"Tuligenga RH, Dugravot A, Tabak AG, Elbaz A, Brunner EJ, Kivimaki M, Singh-Manoux A. Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study. Lancet Diabetes Endocrinol. 2014;2:228\u201335. https:\/\/doi.org\/10.1016\/S2213-8587(13)70192-X.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"1488_CR27","doi-asserted-by":"publisher","first-page":"e396","DOI":"10.7417\/ct.2019.2166","volume":"170","author":"R Saulle","year":"2019","unstructured":"Saulle R, Lia L, De Giusti M, La Torre G. A systematic overview of the scientific literature on the association between Mediterranean diet and the stroke prevention. Clin Ter. 2019;170:e396\u2013408. https:\/\/doi.org\/10.7417\/ct.2019.2166.","journal-title":"Clin Ter"},{"key":"1488_CR28","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s10654-019-00504-7","volume":"34","author":"GC Chen","year":"2019","unstructured":"Chen GC, Neelakantan N, Martin-Calvo N, Koh WP, Yuan JM, Bonaccio M, Iacoviello L, Martinez-Gonzalez MA, Qin LQ, van Dam RM. Adherence to the Mediterranean diet and risk of stroke and stroke subtypes. Eur J Epidemiol. 2019;34:337\u201349. https:\/\/doi.org\/10.1007\/s10654-019-00504-7.","journal-title":"Eur J Epidemiol"},{"key":"1488_CR29","doi-asserted-by":"publisher","first-page":"e0159252","DOI":"10.1371\/journal.pone.0159252","volume":"11","author":"T Liyanage","year":"2016","unstructured":"Liyanage T, Ninomiya T, Wang A, Neal B, Jun M, Wong MG, Jardine M, Hillis GS, Perkovic V. Effects of the Mediterranean diet on cardiovascular outcomes\u2014a systematic review and meta-analysis. PLoS ONE. 2016;11:e0159252.","journal-title":"PLoS ONE"},{"key":"1488_CR30","doi-asserted-by":"publisher","first-page":"102509","DOI":"10.1016\/j.cpcardiol.2024.102509","volume":"49","author":"SA Sebastian","year":"2024","unstructured":"Sebastian SA, Padda I, Johal G. Long-term impact of Mediterranean diet on cardiovascular disease prevention: a systematic review and meta-analysis of randomized controlled trials. Curr Probl Cardiol. 2024;49:102509.","journal-title":"Curr Probl Cardiol"},{"key":"1488_CR31","doi-asserted-by":"publisher","first-page":"3218","DOI":"10.1080\/10408398.2015.1107021","volume":"57","author":"G Grosso","year":"2017","unstructured":"Grosso G, Marventano S, Yang J, Micek A, Pajak A, Scalfi L, Galvano F, Kales SN. A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: are individual components equal? Crit Rev Food Sci Nutr. 2017;57:3218\u201332.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"1488_CR32","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.maturitas.2014.06.014","volume":"79","author":"MD Kontogianni","year":"2014","unstructured":"Kontogianni MD, Panagiotakos DB. Dietary patterns and stroke: a systematic review and re-meta-analysis. Maturitas. 2014;79:41\u20137.","journal-title":"Maturitas"},{"key":"1488_CR33","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1002\/ana.23944","volume":"74","author":"T Psaltopoulou","year":"2013","unstructured":"Psaltopoulou T, Sergentanis TN, Panagiotakos DB, Sergentanis IN, Kosti R, Scarmeas N. Mediterranean diet, stroke, cognitive impairment, and depression: a meta-analysis. Ann Neurol. 2013;74:580\u201391.","journal-title":"Ann Neurol"},{"key":"1488_CR34","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s00394-017-1582-0","volume":"58","author":"V Rosato","year":"2019","unstructured":"Rosato V, Temple NJ, La Vecchia C, Castellan G, Tavani A, Guercio V. Mediterranean diet and cardiovascular disease: a systematic review and meta-analysis of observational studies. Eur J Nutr. 2019;58:173\u201391. https:\/\/doi.org\/10.1007\/s00394-017-1582-0.","journal-title":"Eur J Nutr"},{"key":"1488_CR35","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1161\/CIRCULATIONAHA.108.816736","volume":"119","author":"TT Fung","year":"2009","unstructured":"Fung TT, Rexrode KM, Mantzoros CS, Manson JE, Willett WC, Hu FB. Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation. 2009;119:1093\u2013100.","journal-title":"Circulation"},{"key":"1488_CR36","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.3945\/ajcn.111.012799","volume":"94","author":"H Gardener","year":"2011","unstructured":"Gardener H, Wright CB, Gu Y, Demmer RT, Boden-Albala B, Elkind MS, Sacco RL, Scarmeas N. Mediterranean-style diet and risk of ischemic stroke, myocardial infarction, and vascular death: the Northern Manhattan Study. Am J Clin Nutr. 2011;94:1458\u201364.","journal-title":"Am J Clin Nutr"},{"key":"1488_CR37","doi-asserted-by":"publisher","first-page":"e45458","DOI":"10.1371\/journal.pone.0045458","volume":"7","author":"MP Hoevenaar-Blom","year":"2012","unstructured":"Hoevenaar-Blom MP, Nooyens AC, Kromhout D, Spijkerman AM, Beulens JW, Van Der Schouw YT, Bueno-de-Mesquita B, Verschuren WM. Mediterranean style diet and 12-year incidence of cardiovascular diseases: the EPIC-NL cohort study. PLoS ONE. 2012;7:e45458.","journal-title":"PLoS ONE"},{"key":"1488_CR38","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1007\/s12603-013-0334-y","volume":"17","author":"R Chan","year":"2013","unstructured":"Chan R, Chan D, Woo J. The association of a priori and a posterior dietary patterns with the risk of incident stroke in Chinese older people in Hong Kong. J Nutr Health Aging. 2013;17:866\u201374.","journal-title":"J Nutr Health Aging"},{"key":"1488_CR39","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1017\/S0007114513001931","volume":"111","author":"G Tognon","year":"2014","unstructured":"Tognon G, Lissner L, S\u00e6bye D, Walker KZ, Heitmann BL. The Mediterranean diet in relation to mortality and CVD: a Danish cohort study. Br J Nutr. 2014;111:151\u20139.","journal-title":"Br J Nutr"},{"key":"1488_CR40","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.atherosclerosis.2015.08.039","volume":"243","author":"TG Tektonidis","year":"2015","unstructured":"Tektonidis TG, \u00c5kesson A, Gigante B, Wolk A, Larsson SC. A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: a population-based cohort study. Atherosclerosis. 2015;243:93\u20138.","journal-title":"Atherosclerosis"},{"key":"1488_CR41","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1161\/STROKEAHA.114.007894","volume":"46","author":"G Tsivgoulis","year":"2015","unstructured":"Tsivgoulis G, Psaltopoulou T, Wadley VG, Alexandrov AV, Howard G, Unverzagt FW, Moy C, Howard VJ, Kissela B, Judd SE. Adherence to a Mediterranean diet and prediction of incident stroke. Stroke. 2015;46:780\u20135.","journal-title":"Stroke"},{"key":"1488_CR42","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s00394-015-1092-x","volume":"56","author":"D Stefler","year":"2017","unstructured":"Stefler D, Malyutina S, Kubinova R, Pajak A, Peasey A, Pikhart H, Brunner EJ, Bobak M. Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study. Eur J Nutr. 2017;56:421\u20139.","journal-title":"Eur J Nutr"},{"key":"1488_CR43","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1038\/s41430-018-0103-4","volume":"72","author":"A Aigner","year":"2018","unstructured":"Aigner A, Becher H, Jacobs S, Wilkens LR, Boushey CJ, Le Marchand L, Haiman CA, Maskarinec G. Low diet quality and the risk of stroke mortality: the multiethnic cohort study. Eur J Clin Nutr. 2018;72:1035\u201345.","journal-title":"Eur J Clin Nutr"},{"key":"1488_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12916-018-1082-y","volume":"16","author":"C Galbete","year":"2018","unstructured":"Galbete C, Kr\u00f6ger J, Jannasch F, Iqbal K, Schwingshackl L, Schwedhelm C, Weikert C, Boeing H, Schulze MB. Nordic diet, Mediterranean diet, and the risk of chronic diseases: the EPIC-Potsdam study. BMC Med. 2018;16:1\u201313.","journal-title":"BMC Med"},{"key":"1488_CR45","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1161\/STROKEAHA.117.020258","volume":"49","author":"KE Paterson","year":"2018","unstructured":"Paterson KE, Myint PK, Jennings A, Bain LK, Lentjes MA, Khaw K-T, Welch AA. Mediterranean diet reduces risk of incident stroke in a population with varying cardiovascular disease risk profiles. Stroke. 2018;49:2415\u201320.","journal-title":"Stroke"},{"key":"1488_CR46","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.3945\/jn.111.140061","volume":"141","author":"C Agnoli","year":"2011","unstructured":"Agnoli C, Krogh V, Grioni S, Sieri S, Palli D, Masala G, Sacerdote C, Vineis P, Tumino R, Frasca G. A priori\u2013defined dietary patterns are associated with reduced risk of stroke in a large Italian cohort. J Nutr. 2011;141:1552\u20138.","journal-title":"J Nutr"},{"key":"1488_CR47","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1093\/aje\/kws205","volume":"176","author":"G Misirli","year":"2012","unstructured":"Misirli G, Benetou V, Lagiou P, Bamia C, Trichopoulos D, Trichopoulou A. Relation of the traditional Mediterranean diet to cerebrovascular disease in a Mediterranean population. Am J Epidemiol. 2012;176:1185\u201392.","journal-title":"Am J Epidemiol"},{"key":"1488_CR48","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1001\/jamainternmed.2014.3463","volume":"174","author":"H Schr\u00f6der","year":"2014","unstructured":"Schr\u00f6der H, Salas-Salvad\u00f3 J, Mart\u00ednez-Gonz\u00e1lez MA, F\u00edto M, Corella D, Estruch R, Ros E. Baseline adherence to the Mediterranean diet and major cardiovascular events: Prevenci\u00f3n con Dieta Mediterr\u00e1nea trial. JAMA Intern Med. 2014;174:1690\u20132.","journal-title":"JAMA Intern Med"},{"key":"1488_CR49","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1093\/ije\/dyx145","volume":"46","author":"M Bonaccio","year":"2017","unstructured":"Bonaccio M, Di Castelnuovo A, Pounis G, Costanzo S, Persichillo M, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Investigators M-sS. High adherence to the Mediterranean diet is associated with cardiovascular protection in higher but not in lower socioeconomic groups: prospective findings from the Moli-sani study. Inl J Epidemiol. 2017;46:1478\u201387.","journal-title":"Inl J Epidemiol."},{"key":"1488_CR50","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.ijcard.2018.11.124","volume":"282","author":"F Veglia","year":"2019","unstructured":"Veglia F, Baldassarre D, de Faire U, Kurl S, Smit AJ, Rauramaa R, Giral P, Amato M, Di Minno A, Ravani A. A priori-defined Mediterranean-like dietary pattern predicts cardiovascular events better in north Europe than in Mediterranean countries. Int J Cardiol. 2019;282:88\u201392.","journal-title":"Int J Cardiol"},{"key":"1488_CR51","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1161\/CIRCULATIONAHA.115.017158","volume":"132","author":"M Sotos-Prieto","year":"2015","unstructured":"Sotos-Prieto M, Bhupathiraju SN, Mattei J, Fung TT, Li Y, Pan A, Willett WC, Rimm EB, Hu FB. Changes in diet quality scores and risk of cardiovascular disease among US men and women. Circulation. 2015;132:2212\u20139.","journal-title":"Circulation"},{"key":"1488_CR52","doi-asserted-by":"publisher","unstructured":"Gonz\u00e1lez-Padilla E, Tao Z, S\u00e1nchez-Villegas A, \u00c1lvarez-P\u00e9rez J, Born\u00e9 Y, Sonestedt E. Association between adherence to Swedish dietary guidelines and Mediterranean diet and risk of stroke in a Swedish population. Nutrients. 2022;14. https:\/\/doi.org\/10.3390\/nu14061253.","DOI":"10.3390\/nu14061253"},{"key":"1488_CR53","doi-asserted-by":"publisher","first-page":"e045362","DOI":"10.1136\/bmjopen-2020-045362","volume":"11","author":"KM Livingstone","year":"2021","unstructured":"Livingstone KM, Abbott G, Bowe SJ, Ward J, Milte C, McNaughton SA. Diet quality indices, genetic risk and risk of cardiovascular disease and mortality: a longitudinal analysis of 77 004 UK Biobank participants. BMJ Open. 2021;11:e045362. https:\/\/doi.org\/10.1136\/bmjopen-2020-045362.","journal-title":"BMJ Open"},{"key":"1488_CR54","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1001\/jamainternmed.2020.2176","volume":"180","author":"Z Shan","year":"2020","unstructured":"Shan Z, Li Y, Baden MY, Bhupathiraju SN, Wang DD, Sun Q, Rexrode KM, Rimm EB, Qi L, Willett WC, Manson JE, Qi Q, Hu FB. Association between healthy eating patterns and risk of cardiovascular disease. JAMA Intern Med. 2020;180:1090\u2013100. https:\/\/doi.org\/10.1001\/jamainternmed.2020.2176.","journal-title":"JAMA Intern Med"},{"key":"1488_CR55","doi-asserted-by":"publisher","first-page":"2645","DOI":"10.1093\/eurheartj\/ehaa209","volume":"41","author":"J Li","year":"2020","unstructured":"Li J, Guasch-Ferr\u00e9 M, Chung W, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J. The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. Eur Heart J. 2020;41:2645\u201356.","journal-title":"Eur Heart J"},{"key":"1488_CR56","doi-asserted-by":"publisher","first-page":"101395","DOI":"10.1016\/j.arr.2021.101395","volume":"70","author":"HJ Coelho-Junior","year":"2021","unstructured":"Coelho-Junior HJ, Trichopoulou A, Panza F. Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: a systematic review and meta-analysis. Ageing Res Rev. 2021;70:101395. https:\/\/doi.org\/10.1016\/j.arr.2021.101395.","journal-title":"Ageing Res Rev"},{"key":"1488_CR57","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1186\/s12967-024-05095-w","volume":"22","author":"J Godos","year":"2024","unstructured":"Godos J, Scazzina F, Paterno Castello C, Giampieri F, Quiles JL, Briones Urbano M, Battino M, Galvano F, Iacoviello L, de Gaetano G, Bonaccio M, Grosso G. Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a \u201cPlaneterranean\u201d diet. J Transl Med. 2024;22:294. https:\/\/doi.org\/10.1186\/s12967-024-05095-w.","journal-title":"J Transl Med"},{"issue":"921\u2013930","key":"1488_CR58","doi-asserted-by":"publisher","first-page":"e921","DOI":"10.1016\/j.jand.2015.12.017","volume":"116","author":"B Haring","year":"2016","unstructured":"Haring B, Wu C, Mossavar-Rahmani Y, Snetselaar L, Brunner R, Wallace RB, Neuhouser ML, Wassertheil-Smoller S. No association between dietary patterns and risk for cognitive decline in older women with 9-year follow-up: data from the Women\u2019s Health Initiative Memory Study. J Acad Nutr Diet. 2016;116(921\u2013930):e921. https:\/\/doi.org\/10.1016\/j.jand.2015.12.017.","journal-title":"J Acad Nutr Diet"},{"key":"1488_CR59","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1212\/WNL.0b013e3182904f69","volume":"80","author":"G Tsivgoulis","year":"2013","unstructured":"Tsivgoulis G, Judd S, Letter AJ, Alexandrov AV, Howard G, Nahab F, Unverzagt FW, Moy C, Howard VJ, Kissela B, Wadley VG. Adherence to a Mediterranean diet and risk of incident cognitive impairment. Neurology. 2013;80:1684\u201392. https:\/\/doi.org\/10.1212\/WNL.0b013e3182904f69.","journal-title":"Neurology"},{"key":"1488_CR60","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1159\/000305099","volume":"29","author":"RO Roberts","year":"2010","unstructured":"Roberts RO, Geda YE, Cerhan JR, Knopman DS, Cha RH, Christianson TJ, Pankratz VS, Ivnik RJ, Boeve BF, O\u2019Connor HM, Petersen RC. Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment. Dement Geriatr Cogn Disord. 2010;29:413\u201323. https:\/\/doi.org\/10.1159\/000305099.","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1488_CR61","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1001\/archneurol.2008.536","volume":"66","author":"N Scarmeas","year":"2009","unstructured":"Scarmeas N, Stern Y, Mayeux R, Manly JJ, Schupf N, Luchsinger JA. Mediterranean diet and mild cognitive impairment. Arch Neurol. 2009;66:216\u201325. https:\/\/doi.org\/10.1001\/archneurol.2008.536.","journal-title":"Arch Neurol"},{"key":"1488_CR62","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3233\/JAD-140867","volume":"43","author":"E Olsson","year":"2015","unstructured":"Olsson E, Karlstrom B, Kilander L, Byberg L, Cederholm T, Sjogren P. Dietary patterns and cognitive dysfunction in a 12-year follow-up study of 70 year old men. J Alzheimers Dis. 2015;43:109\u201319. https:\/\/doi.org\/10.3233\/JAD-140867.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR63","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1007\/s00394-014-0811-z","volume":"54","author":"A Trichopoulou","year":"2015","unstructured":"Trichopoulou A, Kyrozis A, Rossi M, Katsoulis M, Trichopoulos D, La Vecchia C, Lagiou P. Mediterranean diet and cognitive decline over time in an elderly Mediterranean population. Eur J Nutr. 2015;54:1311\u201321. https:\/\/doi.org\/10.1007\/s00394-014-0811-z.","journal-title":"Eur J Nutr"},{"key":"1488_CR64","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s10654-017-0330-3","volume":"33","author":"A Bhushan","year":"2018","unstructured":"Bhushan A, Fondell E, Ascherio A, Yuan C, Grodstein F, Willett W. Adherence to Mediterranean diet and subjective cognitive function in men. Eur J Epidemiol. 2018;33:223\u201334. https:\/\/doi.org\/10.1007\/s10654-017-0330-3.","journal-title":"Eur J Epidemiol"},{"key":"1488_CR65","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1007\/s12603-013-0348-5","volume":"17","author":"R Chan","year":"2013","unstructured":"Chan R, Chan D, Woo J. A cross sectional study to examine the association between dietary patterns and cognitive impairment in older Chinese people in Hong Kong. J Nutr Health Aging. 2013;17:757\u201365. https:\/\/doi.org\/10.1007\/s12603-013-0348-5.","journal-title":"J Nutr Health Aging"},{"key":"1488_CR66","doi-asserted-by":"publisher","first-page":"e164","DOI":"10.1038\/tp.2012.91","volume":"2","author":"S Gardener","year":"2012","unstructured":"Gardener S, Gu Y, Rainey-Smith SR, Keogh JB, Clifton PM, Mathieson SL, Taddei K, Mondal A, Ward VK, Scarmeas N, Barnes M, Ellis KA, Head R, Masters CL, Ames D, Macaulay SL, Rowe CC, Szoeke C, Martins RN, Group AR. Adherence to a Mediterranean diet and Alzheimer\u2019s disease risk in an Australian population. Transl Psychiatry. 2012;2:e164. https:\/\/doi.org\/10.1038\/tp.2012.91.","journal-title":"Transl Psychiatry"},{"key":"1488_CR67","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202300271","volume":"68","author":"A Tor-Roca","year":"2024","unstructured":"Tor-Roca A, Sanchez-Pla A, Korosi A, Pallas M, Lucassen PJ, Castellano-Escuder P, Aigner L, Gonzalez-Dominguez R, Manach C, Carmona F, Vegas E, Helmer C, Feart C, Lefevre-Arbogast S, Neuffer J, Lee H, Thuret S, Andres-Lacueva C, Samieri C, Urpi-Sarda M. A Mediterranean diet-based metabolomic score and cognitive decline in older adults: a case-control analysis nested within the three-city cohort study. Mol Nutr Food Res. 2024;68: e2300271. https:\/\/doi.org\/10.1002\/mnfr.202300271.","journal-title":"Mol Nutr Food Res"},{"key":"1488_CR68","doi-asserted-by":"publisher","unstructured":"Feng Y, Wang J, Zhang R, Wang Y, Wang J, Meng H, Cheng H, Zhang J. Mediterranean diet related to 3-year incidence of cognitive decline: results from a cohort study in Chinese rural elders. Nutr Neurosci. 2024;1\u201312. https:\/\/doi.org\/10.1080\/1028415X.2024.2336715.","DOI":"10.1080\/1028415X.2024.2336715"},{"key":"1488_CR69","doi-asserted-by":"publisher","first-page":"125","DOI":"10.5604\/01.3001.0053.4197","volume":"21","author":"A Talhaoui","year":"2023","unstructured":"Talhaoui A, Aboussaleh Y, Bikri S, Rouim FZ, Ahami A. The relationship between adherence to a Mediterranean diet and cognitive impairment among the elderly in Morocco. Acta Neuropsychologica. 2023;21:125\u201338.","journal-title":"Acta Neuropsychologica"},{"key":"1488_CR70","doi-asserted-by":"publisher","first-page":"112143","DOI":"10.1016\/j.exger.2023.112143","volume":"175","author":"J Godos","year":"2023","unstructured":"Godos J, Grosso G, Ferri R, Caraci F, Lanza G, Al-Qahtani WH, Caruso G, Castellano S. Mediterranean diet, mental health, cognitive status, quality of life, and successful aging in southern Italian older adults. Exp Gerontol. 2023;175:112143. https:\/\/doi.org\/10.1016\/j.exger.2023.112143.","journal-title":"Exp Gerontol"},{"key":"1488_CR71","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1001\/jama.2009.1146","volume":"302","author":"C Feart","year":"2009","unstructured":"Feart C, Samieri C, Rondeau V, Amieva H, Portet F, Dartigues JF, Scarmeas N, Barberger-Gateau P. Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA. 2009;302:638\u201348. https:\/\/doi.org\/10.1001\/jama.2009.1146.","journal-title":"JAMA"},{"key":"1488_CR72","doi-asserted-by":"publisher","first-page":"e0182048","DOI":"10.1371\/journal.pone.0182048","volume":"12","author":"CA Anastasiou","year":"2017","unstructured":"Anastasiou CA, Yannakoulia M, Kosmidis MH, Dardiotis E, Hadjigeorgiou GM, Sakka P, Arampatzi X, Bougea A, Labropoulos I, Scarmeas N. Mediterranean diet and cognitive health: initial results from the Hellenic Longitudinal Investigation of Ageing and Diet. PLoS ONE. 2017;12:e0182048. https:\/\/doi.org\/10.1371\/journal.pone.0182048.","journal-title":"PLoS ONE"},{"key":"1488_CR73","doi-asserted-by":"publisher","first-page":"4783","DOI":"10.1016\/j.clnu.2021.06.016","volume":"40","author":"C Nicoli","year":"2021","unstructured":"Nicoli C, Galbussera AA, Bosetti C, Franchi C, Gallus S, Mandelli S, Marcon G, Quadri P, Riso P, Riva E, Lucca U, Tettamanti M. The role of diet on the risk of dementia in the oldest old: the Monzino 80-plus population-based study. Clin Nutr. 2021;40:4783\u201391. https:\/\/doi.org\/10.1016\/j.clnu.2021.06.016.","journal-title":"Clin Nutr"},{"key":"1488_CR74","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s13195-022-00957-1","volume":"14","author":"TOE de Crom","year":"2022","unstructured":"de Crom TOE, Mooldijk SS, Ikram MK, Ikram MA, Voortman T. MIND diet and the risk of dementia: a population-based study. Alzheimers Res Ther. 2022;14:8. https:\/\/doi.org\/10.1186\/s13195-022-00957-1.","journal-title":"Alzheimers Res Ther"},{"key":"1488_CR75","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.1212\/WNL.0000000000201336","volume":"100","author":"I Glans","year":"2023","unstructured":"Glans I, Sonestedt E, Nagga K, Gustavsson AM, Gonzalez-Padilla E, Borne Y, Stomrud E, Melander O, Nilsson PM, Palmqvist S, Hansson O. Association between dietary habits in midlife with dementia incidence over a 20-year period. Neurology. 2023;100:e28\u201337. https:\/\/doi.org\/10.1212\/WNL.0000000000201336.","journal-title":"Neurology"},{"key":"1488_CR76","doi-asserted-by":"publisher","unstructured":"Mamalaki E, Charisis S, Anastasiou CA, Ntanasi E, Georgiadi K, Balomenos V, Kosmidis MH, Dardiotis E, Hadjigeorgiou G, Sakka P, Scarmeas N, Yannakoulia M. The longitudinal association of lifestyle with cognitive health and dementia risk: findings from the HELIAD study. Nutrients. 2022;14. https:\/\/doi.org\/10.3390\/nu14142818.","DOI":"10.3390\/nu14142818"},{"key":"1488_CR77","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.jalz.2018.12.011","volume":"15","author":"DE Hosking","year":"2019","unstructured":"Hosking DE, Eramudugolla R, Cherbuin N, Anstey KJ. MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study. Alzheimers Dement. 2019;15:581\u20139. https:\/\/doi.org\/10.1016\/j.jalz.2018.12.011.","journal-title":"Alzheimers Dement"},{"key":"1488_CR78","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12916-023-02772-3","volume":"21","author":"OM Shannon","year":"2023","unstructured":"Shannon OM, Ranson JM, Gregory S, Macpherson H, Milte C, Lentjes M, Mulligan A, McEvoy C, Griffiths A, Matu J, Hill TR, Adamson A, Siervo M, Minihane AM, Muniz-Tererra G, Ritchie C, Mathers JC, Llewellyn DJ, Stevenson E. Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study. BMC Med. 2023;21:81. https:\/\/doi.org\/10.1186\/s12916-023-02772-3.","journal-title":"BMC Med"},{"key":"1488_CR79","doi-asserted-by":"publisher","first-page":"483","DOI":"10.3233\/JAD-2010-100897","volume":"22","author":"Y Gu","year":"2010","unstructured":"Gu Y, Luchsinger JA, Stern Y, Scarmeas N. Mediterranean diet, inflammatory and metabolic biomarkers, and risk of Alzheimer\u2019s disease. J Alzheimers Dis. 2010;22:483\u201392. https:\/\/doi.org\/10.3233\/JAD-2010-100897.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR80","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1001\/archneur.63.12.noc60109","volume":"63","author":"N Scarmeas","year":"2006","unstructured":"Scarmeas N, Stern Y, Mayeux R, Luchsinger JA. Mediterranean diet, Alzheimer disease, and vascular mediation. Arch Neurol. 2006;63:1709\u201317. https:\/\/doi.org\/10.1001\/archneur.63.12.noc60109.","journal-title":"Arch Neurol"},{"key":"1488_CR81","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1002\/ana.20854","volume":"59","author":"N Scarmeas","year":"2006","unstructured":"Scarmeas N, Stern Y, Tang MX, Mayeux R, Luchsinger JA. Mediterranean diet and risk for Alzheimer\u2019s disease. Ann Neurol. 2006;59:912\u201321. https:\/\/doi.org\/10.1002\/ana.20854.","journal-title":"Ann Neurol"},{"key":"1488_CR82","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/j.jalz.2014.11.009","volume":"11","author":"MC Morris","year":"2015","unstructured":"Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT. MIND diet associated with reduced incidence of Alzheimer\u2019s disease. Alzheimers Dement. 2015;11:1007\u201314. https:\/\/doi.org\/10.1016\/j.jalz.2014.11.009.","journal-title":"Alzheimers Dement"},{"key":"1488_CR83","doi-asserted-by":"crossref","unstructured":"Kheirouri S, Valiei F, Taheraghdam A. Association of plant-rich dietary patterns of mediterranean and MIND with risk of alzheimer disease. Human Nutr Metabol 2024;37(September 2024):200283.","DOI":"10.1016\/j.hnm.2024.200283"},{"key":"1488_CR84","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/j.jacc.2019.11.061","volume":"75","author":"Z Ungvari","year":"2020","unstructured":"Ungvari Z, Tarantini S, Sorond F, Merkely B, Csiszar A. Mechanisms of vascular aging, a geroscience perspective: JACC focus seminar. J Am Coll Cardiol. 2020;75:931\u201341. https:\/\/doi.org\/10.1016\/j.jacc.2019.11.061.","journal-title":"J Am Coll Cardiol"},{"key":"1488_CR85","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1161\/CIRCRESAHA.118.311378","volume":"123","author":"Z Ungvari","year":"2018","unstructured":"Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A. Mechanisms of vascular aging. Circ Res. 2018;123:849\u201367. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.311378.","journal-title":"Circ Res"},{"key":"1488_CR86","doi-asserted-by":"publisher","unstructured":"Fekete M, Major D, Feher A, Fazekas-Pongor V, Lehoczki A. Geroscience and pathology: a new frontier in understanding age-related diseases. Pathol Oncol Res. 2024.https:\/\/doi.org\/10.3389\/pore.2024.1611623.","DOI":"10.3389\/pore.2024.1611623"},{"key":"1488_CR87","doi-asserted-by":"publisher","first-page":"112165","DOI":"10.1016\/j.exger.2023.112165","volume":"176","author":"F Pollicino","year":"2023","unstructured":"Pollicino F, Veronese N, Dominguez LJ, Barbagallo M. Mediterranean diet and mitochondria: New findings. Exp Gerontol. 2023;176:112165. https:\/\/doi.org\/10.1016\/j.exger.2023.112165.","journal-title":"Exp Gerontol"},{"key":"1488_CR88","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1038\/s41430-020-00841-x","volume":"75","author":"OM Shannon","year":"2021","unstructured":"Shannon OM, Ashor AW, Scialo F, Saretzki G, Martin-Ruiz C, Lara J, Matu J, Griffiths A, Robinson N, Lilla L, Stevenson E, Stephan BCM, Minihane AM, Siervo M, Mathers JC. Mediterranean diet and the hallmarks of ageing. Eur J Clin Nutr. 2021;75:1176\u201392. https:\/\/doi.org\/10.1038\/s41430-020-00841-x.","journal-title":"Eur J Clin Nutr"},{"key":"1488_CR89","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1146\/annurev-food-032217-020802","volume":"9","author":"D Corella","year":"2018","unstructured":"Corella D, Coltell O, Macian F, Ordovas JM. Advances in understanding the molecular basis of the Mediterranean diet effect. Annu Rev Food Sci Technol. 2018;9:227\u201349. https:\/\/doi.org\/10.1146\/annurev-food-032217-020802.","journal-title":"Annu Rev Food Sci Technol"},{"key":"1488_CR90","doi-asserted-by":"publisher","first-page":"E652","DOI":"10.1152\/ajpendo.00165.2021","volume":"321","author":"KA Amick","year":"2021","unstructured":"Amick KA, Mahapatra G, Bergstrom J, Gao Z, Craft S, Register TC, Shively CA, Molina AJA. Brain region-specific disruption of mitochondrial bioenergetics in cynomolgus macaques fed a Western versus a Mediterranean diet. Am J Physiol Endocrinol Metab. 2021;321:E652\u201364. https:\/\/doi.org\/10.1152\/ajpendo.00165.2021.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"1488_CR91","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800389","volume":"378","author":"R Estruch","year":"2018","unstructured":"Estruch R, Ros E, Salas-Salvado J, Covas MI, Corella D, Aros F, Gomez-Gracia E, Ruiz-Gutierrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pinto X, Basora J, Munoz MA, Sorli JV, Martinez JA, Fito M, Gea A, Hernan MA, Martinez-Gonzalez MA, Investigators PS. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med. 2018;378: e34. https:\/\/doi.org\/10.1056\/NEJMoa1800389.","journal-title":"N Engl J Med"},{"key":"1488_CR92","doi-asserted-by":"publisher","unstructured":"Knight CJ, Jackson O, Rahman I, Burnett DO, Fruge AD, Greene MW. The Mediterranean diet in the stroke belt: a cross-sectional study on adherence and perceived knowledge, barriers, and benefits. Nutrients. 2019;11. https:\/\/doi.org\/10.3390\/nu11081847.","DOI":"10.3390\/nu11081847"},{"key":"1488_CR93","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1161\/STROKEAHA.117.020258","volume":"49","author":"KE Paterson","year":"2018","unstructured":"Paterson KE, Myint PK, Jennings A, Bain LKM, Lentjes MAH, Khaw KT, Welch AA. Mediterranean diet reduces risk of incident stroke in a population with varying cardiovascular disease risk profiles. Stroke. 2018;49:2415\u201320. https:\/\/doi.org\/10.1161\/STROKEAHA.117.020258.","journal-title":"Stroke"},{"key":"1488_CR94","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1161\/STROKEAHA.114.007894","volume":"46","author":"G Tsivgoulis","year":"2015","unstructured":"Tsivgoulis G, Psaltopoulou T, Wadley VG, Alexandrov AV, Howard G, Unverzagt FW, Moy C, Howard VJ, Kissela B, Judd SE. Adherence to a Mediterranean diet and prediction of incident stroke. Stroke. 2015;46:780\u20135. https:\/\/doi.org\/10.1161\/STROKEAHA.114.007894.","journal-title":"Stroke"},{"key":"1488_CR95","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.1161\/STROKEAHA.114.006306","volume":"46","author":"S Lakkur","year":"2015","unstructured":"Lakkur S, Judd SE. Diet and stroke: recent evidence supporting a Mediterranean-style diet and food in the primary prevention of stroke. Stroke. 2015;46:2007\u201311. https:\/\/doi.org\/10.1161\/STROKEAHA.114.006306.","journal-title":"Stroke"},{"key":"1488_CR96","doi-asserted-by":"publisher","unstructured":"Ungvari Z, Fekete M, Fekete JT, Grosso G, Ungvari A, Gyorffy B. Adherence to the Mediterranean diet and its protective effects against colorectal cancer: a meta-analysis of 26 studies with 2,217,404 participants. Geroscience. 2024.https:\/\/doi.org\/10.1007\/s11357-11024-01296-11359. https:\/\/doi.org\/10.1007\/s11357-024-01296-9.","DOI":"10.1007\/s11357-11024-01296-11359"},{"key":"1488_CR97","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1038\/bjc.2016.245","volume":"115","author":"V Rosato","year":"2016","unstructured":"Rosato V, Guercio V, Bosetti C, Negri E, Serraino D, Giacosa A, Montella M, La Vecchia C, Tavani A. Mediterranean diet and colorectal cancer risk: a pooled analysis of three Italian case-control studies. Br J Cancer. 2016;115:862\u20135. https:\/\/doi.org\/10.1038\/bjc.2016.245.","journal-title":"Br J Cancer"},{"issue":"Suppl 2","key":"1488_CR98","doi-asserted-by":"publisher","first-page":"S14","DOI":"10.1186\/1471-2482-13-S2-S14","volume":"13","author":"G Grosso","year":"2013","unstructured":"Grosso G, Buscemi S, Galvano F, Mistretta A, Marventano S, La Vela V, Drago F, Gangi S, Basile F, Biondi A. Mediterranean diet and cancer: epidemiological evidence and mechanism of selected aspects. BMC Surg. 2013;13(Suppl 2):S14. https:\/\/doi.org\/10.1186\/1471-2482-13-S2-S14.","journal-title":"BMC Surg"},{"key":"1488_CR99","doi-asserted-by":"publisher","unstructured":"Papadopoulou SK, Detopoulou P, Voulgaridou G, Tsoumana D, Spanoudaki M, Sadikou F, Papadopoulou VG, Zidrou C, Chatziprodromidou IP, Giaginis C, Nikolaidis P. Mediterranean diet and sarcopenia features in apparently healthy adults over 65 years: a systematic review. Nutrients. 2023;15. https:\/\/doi.org\/10.3390\/nu15051104.","DOI":"10.3390\/nu15051104"},{"key":"1488_CR100","doi-asserted-by":"publisher","unstructured":"Cacciatore S, Calvani R, Marzetti E, Picca A, Coelho-Junior HJ, Martone AM, Massaro C, Tosato M, Landi F. Low adherence to mediterranean diet is associated with probable sarcopenia in community-dwelling older adults: results from the longevity check-up (lookup) 7+ project. Nutrients. 2023;15. https:\/\/doi.org\/10.3390\/nu15041026.","DOI":"10.3390\/nu15041026"},{"key":"1488_CR101","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.ophtha.2016.09.019","volume":"124","author":"RE Hogg","year":"2017","unstructured":"Hogg RE, Woodside JV, McGrath A, Young IS, Vioque JL, Chakravarthy U, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Fletcher AE. Mediterranean diet score and its association with age-related macular degeneration: the European Eye Study. Ophthalmology. 2017;124:82\u20139. https:\/\/doi.org\/10.1016\/j.ophtha.2016.09.019.","journal-title":"Ophthalmology"},{"key":"1488_CR102","doi-asserted-by":"publisher","first-page":"e926","DOI":"10.1111\/aos.13775","volume":"96","author":"M Raimundo","year":"2018","unstructured":"Raimundo M, Mira F, Cachulo MDL, Barreto P, Ribeiro L, Farinha C, Lains I, Nunes S, Alves D, Figueira J, Merle BM, Delcourt C, Santos L, Silva R. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3. Acta Ophthalmol. 2018;96:e926\u201332. https:\/\/doi.org\/10.1111\/aos.13775.","journal-title":"Acta Ophthalmol"},{"key":"1488_CR103","doi-asserted-by":"publisher","unstructured":"Keenan TD, Agron E, Mares J, Clemons TE, van Asten F, Swaroop A, Chew EY, Age-Related Eye Disease S, Research G. Adherence to the Mediterranean diet and progression to late age-related macular degeneration in the age-related eye disease studies 1 and 2. Ophthalmology. 2020;127:1515\u20131528. https:\/\/doi.org\/10.1016\/j.ophtha.2020.04.030.","DOI":"10.1016\/j.ophtha.2020.04.030"},{"key":"1488_CR104","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1001\/jamaophthalmol.2022.5404","volume":"141","author":"GK Broadhead","year":"2023","unstructured":"Broadhead GK, Agron E, Peprah D, Keenan TDL, Lawler TP, Mares J, Chew EY, Investigators AA. Association of dietary nitrate and a Mediterranean diet with age-related macular degeneration among US adults: the age-related eye disease study (AREDS) and AREDS2. JAMA Ophthalmol. 2023;141:130\u20139. https:\/\/doi.org\/10.1001\/jamaophthalmol.2022.5404.","journal-title":"JAMA Ophthalmol"},{"key":"1488_CR105","doi-asserted-by":"publisher","unstructured":"Fekete M, Szarvas Z, Fazekas-Pongor V, Feher A, Csipo T, Forrai J, Dosa N, Peterfi A, Lehoczki A, Tarantini S, Varga JT. Nutrition strategies promoting healthy aging: from improvement of cardiovascular and brain health to prevention of age-associated diseases. Nutrients. 2022;15. https:\/\/doi.org\/10.3390\/nu15010047.","DOI":"10.3390\/nu15010047"},{"key":"1488_CR106","doi-asserted-by":"publisher","unstructured":"Fekete M, Szarvas Z, Fazekas-Pongor V, Lehoczki A, Tarantini S, Varga JT. Effects of omega-3 supplementation on quality of life, nutritional status, inflammatory parameters, lipid profile, exercise tolerance and inhaled medications in chronic obstructive pulmonary disease. Ann Palliat Med. 2022;11:2819\u20132829. https:\/\/doi.org\/10.21037\/apm-22-254.","DOI":"10.21037\/apm-22-254"},{"key":"1488_CR107","doi-asserted-by":"publisher","unstructured":"Fekete M, Csipo T, Fazekas-Pongor V, Feher A, Szarvas Z, Kaposvari C, Horvath K, Lehoczki A, Tarantini S, Varga JT. The effectiveness of supplementation with key vitamins, minerals, antioxidants and specific nutritional supplements in COPD-a review. Nutrients. 2023;15. https:\/\/doi.org\/10.3390\/nu15122741.","DOI":"10.3390\/nu15122741"},{"key":"1488_CR108","doi-asserted-by":"publisher","unstructured":"Fekete M, Lehoczki A, Major D, Fazekas-Pongor V, Csipo T, Tarantini S, Csizmadia Z, Varga JT. Exploring the influence of gut-brain axis modulation on cognitive health: a comprehensive review of prebiotics, probiotics, and symbiotics. Nutrients. 2024;16. https:\/\/doi.org\/10.3390\/nu16060789.","DOI":"10.3390\/nu16060789"},{"key":"1488_CR109","doi-asserted-by":"publisher","unstructured":"Fekete M, Lehoczki A, Tarantini S, Fazekas-Pongor V, Csipo T, Csizmadia Z, Varga JT. Improving cognitive function with nutritional supplements in aging: a comprehensive narrative review of clinical studies investigating the effects of vitamins, minerals, antioxidants, and other dietary supplements. Nutrients. 2023;15. https:\/\/doi.org\/10.3390\/nu15245116.","DOI":"10.3390\/nu15245116"},{"key":"1488_CR110","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1001\/archinte.167.22.2461","volume":"167","author":"PN Mitrou","year":"2007","unstructured":"Mitrou PN, Kipnis V, Thiebaut AC, Reedy J, Subar AF, Wirfalt E, Flood A, Mouw T, Hollenbeck AR, Leitzmann MF, Schatzkin A. Mediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH-AARP Diet and Health Study. Arch Intern Med. 2007;167:2461\u20138. https:\/\/doi.org\/10.1001\/archinte.167.22.2461.","journal-title":"Arch Intern Med"},{"issue":"Suppl 2","key":"1488_CR111","first-page":"83","volume":"43","author":"O Moreiras-Varela","year":"1989","unstructured":"Moreiras-Varela O. The Mediterranean diet in Spain. Eur J Clin Nutr. 1989;43(Suppl 2):83\u20137.","journal-title":"Eur J Clin Nutr"},{"key":"1488_CR112","doi-asserted-by":"publisher","first-page":"2000473","DOI":"10.1002\/mnfr.202000473","volume":"64","author":"NB Poulsen","year":"2020","unstructured":"Poulsen NB, Lambert MNT, Jeppesen PB. The effect of plant derived bioactive compounds on inflammation: a systematic review and meta-analysis. Mol Nutr Food Res. 2020;64:2000473.","journal-title":"Mol Nutr Food Res"},{"key":"1488_CR113","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.neurol.2019.08.005","volume":"175","author":"GC Roman","year":"2019","unstructured":"Roman GC, Jackson RE, Gadhia R, Roman AN, Reis J. Mediterranean diet: the role of long-chain omega-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease. Rev Neurol (Paris). 2019;175:724\u201341. https:\/\/doi.org\/10.1016\/j.neurol.2019.08.005.","journal-title":"Rev Neurol (Paris)"},{"key":"1488_CR114","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1093\/gerona\/glx227","volume":"73","author":"V Tosti","year":"2018","unstructured":"Tosti V, Bertozzi B, Fontana L. Health benefits of the Mediterranean diet: metabolic and molecular mechanisms. J Gerontol A Biol Sci Med Sci. 2018;73:318\u201326. https:\/\/doi.org\/10.1093\/gerona\/glx227.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"1488_CR115","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/j.cmet.2012.04.003","volume":"15","author":"NL Price","year":"2012","unstructured":"Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab. 2012;15:675\u201390. https:\/\/doi.org\/10.1016\/j.cmet.2012.04.003.","journal-title":"Cell Metab"},{"key":"1488_CR116","doi-asserted-by":"publisher","unstructured":"Danz ED, Skramsted J, Henry N, Bennett JA, Keller RS. Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. Free Radic Biol Med. 2009;46:1589\u20131597. S0891\u20135849(09)00154\u20133 [pii https:\/\/doi.org\/10.1016\/j.freeradbiomed.2009.03.011.","DOI":"10.1016\/j.freeradbiomed.2009.03.011"},{"key":"1488_CR117","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1161\/HYPERTENSIONAHA.111.01009.HYPERTENSIONAHA.111.01009[pii]","volume":"62","author":"A Carrizzo","year":"2013","unstructured":"Carrizzo A, Puca A, Damato A, Marino M, Franco E, Pompeo F, Traficante A, Civitillo F, Santini L, Trimarco V, Vecchione C. Resveratrol improves vascular function in patients with hypertension and dyslipidemia by modulating NO metabolism. Hypertension. 2013;62:359\u201366. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.111.01009.HYPERTENSIONAHA.111.01009[pii].","journal-title":"Hypertension"},{"key":"1488_CR118","doi-asserted-by":"publisher","unstructured":"Toth P, Tarantini S, Tucsek Z, Ashpole NM, Sosnowska D, Gautam T, Ballabh P, Koller A, Sonntag WE, Csiszar A, Ungvari ZI. Resveratrol treatment rescues neurovascular coupling in aged mice:role of improved cerebromicrovascular endothelial function and down-regulation of NADPH oxidas. Am J Physiol Heart Circ Physiol. 2014;306:H299\u2013308. ajpheart.00744.2013 [pii]. https:\/\/doi.org\/10.1152\/ajpheart.00744.2013.","DOI":"10.1152\/ajpheart.00744.2013"},{"key":"1488_CR119","doi-asserted-by":"publisher","first-page":"3472","DOI":"10.3390\/ijms23073472","volume":"23","author":"I Mora","year":"2022","unstructured":"Mora I, Arola L, Caimari A, Escot\u00e9 X, Puiggr\u00f2s F. Structured long-chain omega-3 fatty acids for improvement of cognitive function during aging. Int J Mol Sci. 2022;23:3472.","journal-title":"Int J Mol Sci"},{"key":"1488_CR120","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1124\/pr.117.014092","volume":"70","author":"S Laye","year":"2018","unstructured":"Laye S, Nadjar A, Joffre C, Bazinet RP. Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology. Pharmacol Rev. 2018;70:12\u201338. https:\/\/doi.org\/10.1124\/pr.117.014092.","journal-title":"Pharmacol Rev"},{"key":"1488_CR121","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/s0306-4522(99)00219-5","volume":"94","author":"BM McGahon","year":"1999","unstructured":"McGahon BM, Martin DS, Horrobin DF, Lynch MA. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience. 1999;94:305\u201314. https:\/\/doi.org\/10.1016\/s0306-4522(99)00219-5.","journal-title":"Neuroscience"},{"key":"1488_CR122","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1093\/cercor\/bhz083","volume":"30","author":"BE Carbone","year":"2020","unstructured":"Carbone BE, Abouleish M, Watters KE, Vogel S, Ribic A, Schroeder OH, Bader BM, Biederer T. Synaptic connectivity and cortical maturation are promoted by the omega-3 fatty acid docosahexaenoic acid. Cereb Cortex. 2020;30:226\u201340. https:\/\/doi.org\/10.1093\/cercor\/bhz083.","journal-title":"Cereb Cortex"},{"key":"1488_CR123","doi-asserted-by":"publisher","unstructured":"Kaufman CS, Vidoni ED, Burns JM, Alwatban MR, Billinger SA. Self-reported omega-3 supplement use moderates the association between age and exercising cerebral blood flow velocity in older adults. Nutrients. 2020;12. https:\/\/doi.org\/10.3390\/nu12030697.","DOI":"10.3390\/nu12030697"},{"key":"1488_CR124","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.3233\/JAD-170281","volume":"58","author":"DG Amen","year":"2017","unstructured":"Amen DG, Harris WS, Kidd PM, Meysami S, Raji CA. Quantitative erythrocyte omega-3 EPA plus DHA levels are related to higher regional cerebral blood flow on brain SPECT. J Alzheimers Dis. 2017;58:1189\u201399. https:\/\/doi.org\/10.3233\/JAD-170281.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR125","doi-asserted-by":"publisher","unstructured":"Simonetto M, Infante M, Sacco RL, Rundek T, Della-Morte D. A Novel anti-inflammatory role of omega-3 PUFAs in prevention and treatment of atherosclerosis and vascular cognitive impairment and dementia. Nutrients. 2019;11. https:\/\/doi.org\/10.3390\/nu11102279.","DOI":"10.3390\/nu11102279"},{"key":"1488_CR126","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1002\/mnfr.201100710","volume":"56","author":"PC Calder","year":"2012","unstructured":"Calder PC. The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability. Mol Nutr Food Res. 2012;56:1073\u201380. https:\/\/doi.org\/10.1002\/mnfr.201100710.","journal-title":"Mol Nutr Food Res"},{"key":"1488_CR127","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s40520-024-02823-6","volume":"36","author":"J Godos","year":"2024","unstructured":"Godos J, Micek A, Currenti W, Franchi C, Poli A, Battino M, Dolci A, Ricci C, Ungvari Z, Grosso G. Fish consumption, cognitive impairment and dementia: an updated dose-response meta-analysis of observational studies. Aging Clin Exp Res. 2024;36:171. https:\/\/doi.org\/10.1007\/s40520-024-02823-6.","journal-title":"Aging Clin Exp Res"},{"key":"1488_CR128","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1017\/S136898001800037X","volume":"21","author":"AT Bakre","year":"2018","unstructured":"Bakre AT, Chen R, Khutan R, Wei L, Smith T, Qin G, Danat IM, Zhou W, Schofield P, Clifford A. Association between fish consumption and risk of dementia: a new study from China and a systematic literature review and meta-analysis. Public Health Nutr. 2018;21:1921\u201332.","journal-title":"Public Health Nutr"},{"key":"1488_CR129","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1017\/S1368980017003834","volume":"21","author":"A Jayedi","year":"2018","unstructured":"Jayedi A, Shab-Bidar S, Eimeri S, Djafarian K. Fish consumption and risk of all-cause and cardiovascular mortality: a dose\u2013response meta-analysis of prospective observational studies. Public Health Nutr. 2018;21:1297\u2013306.","journal-title":"Public Health Nutr"},{"key":"1488_CR130","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.phrs.2017.12.003","volume":"129","author":"N Gorji","year":"2018","unstructured":"Gorji N, Moeini R, Memariani Z. Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer\u2019s disease: a neuropharmacological review of their bioactive constituents. Pharmacol Res. 2018;129:115\u201327. https:\/\/doi.org\/10.1016\/j.phrs.2017.12.003.","journal-title":"Pharmacol Res"},{"key":"1488_CR131","doi-asserted-by":"publisher","unstructured":"Nishi SK, Sala-Vila A, Julvez J, Sabate J, Ros E. Impact of nut consumption on cognition across the lifespan. Nutrients. 2023;15. https:\/\/doi.org\/10.3390\/nu15041000.","DOI":"10.3390\/nu15041000"},{"key":"1488_CR132","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.ajcnut.2023.05.032","volume":"118","author":"J Ni","year":"2023","unstructured":"Ni J, Nishi SK, Babio N, Ros E, Basterra-Gortari FJ, Corella D, O C, Martinez JA, Alonso-Gomez AM, Warnberg J, Vioque J, Romaguera D, Lopez-Miranda J, Estruch R, Tinahones FJ, Santos-Lozano JM, Serra-Majem L, Cano-Ibanez N, Tur JA, Fernandez-Garcia JM, Pinto X, Delgado-Rodriguez M, Matia-Martin P, Vidal J, Vazquez C, Daimiel L, Fernandez-Aranda F, Ruiz-Canela M, Mestres Sola C, Portoles O, et al. Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study. Am J Clin Nutr. 2023;118:360\u20138. https:\/\/doi.org\/10.1016\/j.ajcnut.2023.05.032.","journal-title":"Am J Clin Nutr"},{"key":"1488_CR133","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-024-01365-z","author":"B Bizzozero-Peroni","year":"2024","unstructured":"Bizzozero-Peroni B, Diaz-Goni V, Beneit N, Oliveira A, Jimenez-Lopez E, Martinez-Vizcaino V, Mesas AE. Nut consumption is associated with a lower risk of all-cause dementia in adults: a community-based cohort study from the UK Biobank. Geroscience. 2024. https:\/\/doi.org\/10.1007\/s11357-024-01365-z.","journal-title":"Geroscience"},{"key":"1488_CR134","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1080\/10408398.2011.596955","volume":"54","author":"G Grosso","year":"2014","unstructured":"Grosso G, Mistretta A, Frigiola A, Gruttadauria S, Biondi A, Basile F, Vitaglione P, D\u2019Orazio N, Galvano F. Mediterranean diet and cardiovascular risk factors: a systematic review. Crit Rev Food Sci Nutr. 2014;54:593\u2013610. https:\/\/doi.org\/10.1080\/10408398.2011.596955.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"1488_CR135","doi-asserted-by":"publisher","first-page":"1791","DOI":"10.3945\/jn.111.141333","volume":"141","author":"E Wolff","year":"2011","unstructured":"Wolff E, Vergnes MF, Portugal H, Defoort C, Amiot-Carlin MJ, Lairon D, Nicolay A. Cholesterol-absorber status modifies the LDL cholesterol-lowering effect of a Mediterranean-type diet in adults with moderate cardiovascular risk factors. J Nutr. 2011;141:1791\u20138. https:\/\/doi.org\/10.3945\/jn.111.141333.","journal-title":"J Nutr"},{"key":"1488_CR136","doi-asserted-by":"publisher","unstructured":"Hernaez A, Castaner O, Goday A, Ros E, Pinto X, Estruch R, Salas-Salvado J, Corella D, Aros F, Serra-Majem L, Martinez-Gonzalez MA, Fiol M, Lapetra J, de la Torre R, Lopez-Sabater MC, Fito M. The Mediterranean diet decreases LDL atherogenicity in high cardiovascular risk individuals: a randomized controlled trial. Mol Nutr Food Res. 2017;61. https:\/\/doi.org\/10.1002\/mnfr.201601015.","DOI":"10.1002\/mnfr.201601015"},{"key":"1488_CR137","doi-asserted-by":"publisher","first-page":"3705","DOI":"10.3390\/nu7053705","volume":"7","author":"A Bedard","year":"2015","unstructured":"Bedard A, Corneau L, Lamarche B, Dodin S, Lemieux S. Sex Differences in the Impact of the Mediterranean diet on LDL particle size distribution and oxidation. Nutrients. 2015;7:3705\u201323. https:\/\/doi.org\/10.3390\/nu7053705.","journal-title":"Nutrients"},{"key":"1488_CR138","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.jnutbio.2011.02.016","volume":"23","author":"J Barona","year":"2012","unstructured":"Barona J, Jones JJ, Kopec RE, Comperatore M, Andersen C, Schwartz SJ, Lerman RH, Fernandez ML. A Mediterranean-style low-glycemic-load diet increases plasma carotenoids and decreases LDL oxidation in women with metabolic syndrome. J Nutr Biochem. 2012;23:609\u201315. https:\/\/doi.org\/10.1016\/j.jnutbio.2011.02.016.","journal-title":"J Nutr Biochem"},{"key":"1488_CR139","unstructured":"Mediterranean diet delivers a punch to LDL cholesterol. Mayo Clin Health Lett. 2011;29:4."},{"key":"1488_CR140","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1007\/s11306-019-1579-1","volume":"15","author":"C Zhu","year":"2019","unstructured":"Zhu C, Sawrey-Kubicek L, Beals E, Hughes RL, Rhodes CH, Sacchi R, Zivkovic AM. The HDL lipidome is widely remodeled by fast food versus Mediterranean diet in 4 days. Metabolomics. 2019;15:114. https:\/\/doi.org\/10.1007\/s11306-019-1579-1.","journal-title":"Metabolomics"},{"key":"1488_CR141","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1093\/ajcn\/nqab246","volume":"114","author":"A Sanllorente","year":"2021","unstructured":"Sanllorente A, Soria-Florido MT, Castaner O, Lassale C, Salas-Salvado J, Martinez-Gonzalez MA, Subirana I, Ros E, Corella D, Estruch R, Tinahones FJ, Hernaez A, Fito M. A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial. Am J Clin Nutr. 2021;114:1666\u201374. https:\/\/doi.org\/10.1093\/ajcn\/nqab246.","journal-title":"Am J Clin Nutr"},{"key":"1488_CR142","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1159\/000253483","volume":"28","author":"C Berr","year":"2009","unstructured":"Berr C, Portet F, Carriere I, Akbaraly TN, Feart C, Gourlet V, Combe N, Barberger-Gateau P, Ritchie K. Olive oil and cognition: results from the three-city study. Dement Geriatr Cogn Disord. 2009;28:357\u201364. https:\/\/doi.org\/10.1159\/000253483.","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1488_CR143","doi-asserted-by":"publisher","first-page":"e13076","DOI":"10.1111\/acel.13076","volume":"19","author":"E Lauretti","year":"2020","unstructured":"Lauretti E, Nenov M, Dincer O, Iuliano L, Pratico D. Extra virgin olive oil improves synaptic activity, short-term plasticity, memory, and neuropathology in a tauopathy model. Aging Cell. 2020;19:e13076. https:\/\/doi.org\/10.1111\/acel.13076.","journal-title":"Aging Cell"},{"key":"1488_CR144","doi-asserted-by":"publisher","first-page":"801","DOI":"10.3233\/JAD-200405","volume":"78","author":"M Tsolaki","year":"2020","unstructured":"Tsolaki M, Lazarou E, Kozori M, Petridou N, Tabakis I, Lazarou I, Karakota M, Saoulidis I, Melliou E, Magiatis P. A Randomized clinical trial of Greek high phenolic early harvest extra virgin olive oil in mild cognitive impairment: the MICOIL pilot study. J Alzheimers Dis. 2020;78:801\u201317. https:\/\/doi.org\/10.3233\/JAD-200405.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR145","doi-asserted-by":"publisher","first-page":"e2410021","DOI":"10.1001\/jamanetworkopen.2024.10021","volume":"7","author":"AJ Tessier","year":"2024","unstructured":"Tessier AJ, Cortese M, Yuan C, Bjornevik K, Ascherio A, Wang DD, Chavarro JE, Stampfer MJ, Hu FB, Willett WC, Guasch-Ferre M. Consumption of olive oil and diet quality and risk of dementia-related death. JAMA Netw Open. 2024;7:e2410021. https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.10021.","journal-title":"JAMA Netw Open"},{"key":"1488_CR146","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1089\/rej.2012.1346","volume":"15","author":"V Pitozzi","year":"2012","unstructured":"Pitozzi V, Jacomelli M, Catelan D, Servili M, Taticchi A, Biggeri A, Dolara P, Giovannelli L. Long-term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: role of oxidative stress. Rejuvenation Res. 2012;15:601\u201312. https:\/\/doi.org\/10.1089\/rej.2012.1346.","journal-title":"Rejuvenation Res"},{"key":"1488_CR147","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12967-018-1386-x","volume":"16","author":"E Mazza","year":"2018","unstructured":"Mazza E, Fava A, Ferro Y, Rotundo S, Romeo S, Bosco D, Pujia A, Montalcini T. Effect of the replacement of dietary vegetable oils with a low dose of extravirgin olive oil in the Mediterranean diet on cognitive functions in the elderly. J Transl Med. 2018;16:10. https:\/\/doi.org\/10.1186\/s12967-018-1386-x.","journal-title":"J Transl Med"},{"key":"1488_CR148","doi-asserted-by":"publisher","unstructured":"Boronat A, Serreli G, Rodriguez-Morato J, Deiana M, de la Torre R. Olive oil phenolic compounds\u2019 activity against age-associated cognitive decline: clinical and experimental evidence. Antioxidants (Basel). 2023;12. https:\/\/doi.org\/10.3390\/antiox12071472","DOI":"10.3390\/antiox12071472"},{"key":"1488_CR149","doi-asserted-by":"publisher","first-page":"429","DOI":"10.3390\/nu13020429","volume":"13","author":"G Caprara","year":"2021","unstructured":"Caprara G. Mediterranean-type dietary pattern and physical activity: the winning combination to counteract the rising burden of non-communicable diseases (NCDS). Nutrients. 2021;13:429.","journal-title":"Nutrients"},{"key":"1488_CR150","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.neurol.2019.07.017","volume":"175","author":"GC Rom\u00e1n","year":"2019","unstructured":"Rom\u00e1n GC, Jackson RE, Reis J, Rom\u00e1n AN, Toledo JB, Toledo E. Extra-virgin olive oil for potential prevention of Alzheimer disease. Revue Neurologique. 2019;175:705\u201323.","journal-title":"Revue Neurologique"},{"key":"1488_CR151","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.3390\/foods9081014","volume":"9","author":"C Jimenez-Lopez","year":"2020","unstructured":"Jimenez-Lopez C, Carpena M, Louren\u00e7o-Lopes C, Gallardo-Gomez M, Lorenzo JM, Barba FJ, Prieto MA, Simal-Gandara J. Bioactive compounds and quality of extra virgin olive oil. Foods. 2020;9:1014.","journal-title":"Foods"},{"key":"1488_CR152","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3233\/JAD-171121","volume":"64","author":"M Vassilaki","year":"2018","unstructured":"Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Mediterranean diet, its components, and amyloid imaging biomarkers. J Alzheimers Dis. 2018;64:281\u201390. https:\/\/doi.org\/10.3233\/JAD-171121.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR153","doi-asserted-by":"publisher","first-page":"e1789","DOI":"10.1212\/WNL.0000000000005527","volume":"90","author":"V Berti","year":"2018","unstructured":"Berti V, Walters M, Sterling J, Quinn CG, Logue M, Andrews R, Matthews DC, Osorio RS, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Mosconi L. Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults. Neurology. 2018;90:e1789\u201398. https:\/\/doi.org\/10.1212\/WNL.0000000000005527.","journal-title":"Neurology"},{"key":"1488_CR154","doi-asserted-by":"publisher","first-page":"e2259","DOI":"10.1212\/WNL.0000000000207176","volume":"100","author":"P Agarwal","year":"2023","unstructured":"Agarwal P, Leurgans SE, Agrawal S, Aggarwal NT, Cherian LJ, James BD, Dhana K, Barnes LL, Bennett DA, Schneider JA. Association of Mediterranean-DASH intervention for neurodegenerative delay and Mediterranean diets With Alzheimer disease pathology. Neurology. 2023;100:e2259\u201368. https:\/\/doi.org\/10.1212\/WNL.0000000000207176.","journal-title":"Neurology"},{"key":"1488_CR155","doi-asserted-by":"publisher","unstructured":"Yang E, Wang J, Woodie LN, Greene MW, Kaddoumi A. Oleocanthal ameliorates metabolic and behavioral phenotypes in a mouse model of Alzheimer\u2019s disease. Molecules. 2023;28. https:\/\/doi.org\/10.3390\/molecules28145592.","DOI":"10.3390\/molecules28145592"},{"key":"1488_CR156","doi-asserted-by":"publisher","unstructured":"Tajmim A, Cuevas-Ocampo AK, Siddique AB, Qusa MH, King JA, Abdelwahed KS, Sonju JJ, El Sayed KA. (-)-Oleocanthal nutraceuticals for Alzheimer\u2019s disease amyloid pathology: novel oral formulations, therapeutic, and molecular insights in 5xFAD transgenic mice model. Nutrients. 2021;13. https:\/\/doi.org\/10.3390\/nu13051702.","DOI":"10.3390\/nu13051702"},{"key":"1488_CR157","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1111\/j.1471-4159.2009.06224.x","volume":"110","author":"W Li","year":"2009","unstructured":"Li W, Sperry JB, Crowe A, Trojanowski JQ, Smith AB 3rd, Lee VM. Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau. J Neurochem. 2009;110:1339\u201351. https:\/\/doi.org\/10.1111\/j.1471-4159.2009.06224.x.","journal-title":"J Neurochem"},{"key":"1488_CR158","doi-asserted-by":"publisher","first-page":"104476","DOI":"10.1016\/j.phrs.2019.104476","volume":"150","author":"JY Chen","year":"2019","unstructured":"Chen JY, Zhu Q, Zhang S, OuYang D, Lu JH. Resveratrol in experimental Alzheimer\u2019 disease models: a systematic review of preclinical studies. Pharmacol Res. 2019;150:104476. https:\/\/doi.org\/10.1016\/j.phrs.2019.104476.","journal-title":"Pharmacol Res"},{"key":"1488_CR159","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.neuroscience.2007.08.018","volume":"149","author":"GW Arendash","year":"2007","unstructured":"Arendash GW, Jensen MT, Salem N Jr, Hussein N, Cracchiolo J, Dickson A, Leighty R, Potter H. A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimer\u2019s transgenic mice. Neuroscience. 2007;149:286\u2013302. https:\/\/doi.org\/10.1016\/j.neuroscience.2007.08.018.","journal-title":"Neuroscience"},{"key":"1488_CR160","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.3233\/JAD-210007","volume":"83","author":"A Tofiq","year":"2021","unstructured":"Tofiq A, Zetterberg H, Blennow K, Basun H, Cederholm T, Eriksdotter M, Faxen-Irving G, Hjorth E, Jerneren F, Schultzberg M, Wahlund LO, Palmblad J, Freund-Levi Y. Effects of peroral omega-3 fatty acid supplementation on cerebrospinal fluid biomarkers in patients with Alzheimer\u2019s disease: a randomized controlled trial-the OmegAD study. J Alzheimers Dis. 2021;83:1291\u2013301. https:\/\/doi.org\/10.3233\/JAD-210007.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR161","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.3233\/JAD-170579","volume":"62","author":"M Fiala","year":"2018","unstructured":"Fiala M, Restrepo L, Pellegrini M. Immunotherapy of mild cognitive impairment by omega-3 supplementation: why are amyloid-beta antibodies and omega-3 not working in clinical trials? J Alzheimers Dis. 2018;62:1013\u201322. https:\/\/doi.org\/10.3233\/JAD-170579.","journal-title":"J Alzheimers Dis"},{"key":"1488_CR162","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1186\/s12974-016-0721-5","volume":"13","author":"KE Hopperton","year":"2016","unstructured":"Hopperton KE, Trepanier MO, Giuliano V, Bazinet RP. Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-beta 1\u201340 in mice. J Neuroinflammation. 2016;13:257. https:\/\/doi.org\/10.1186\/s12974-016-0721-5.","journal-title":"J Neuroinflammation"},{"key":"1488_CR163","doi-asserted-by":"publisher","first-page":"100184","DOI":"10.1016\/j.advnut.2024.100184","volume":"15","author":"AP van Soest","year":"2024","unstructured":"van Soest AP, Beers S, van de Rest O, de Groot LC. The Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet for the aging brain: a systematic review. Adv Nutr. 2024;15:100184. https:\/\/doi.org\/10.1016\/j.advnut.2024.100184.","journal-title":"Adv Nutr"},{"key":"1488_CR164","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1001\/jamapsychiatry.2023.0800","volume":"80","author":"H Chen","year":"2023","unstructured":"Chen H, Dhana K, Huang Y, Huang L, Tao Y, Liu X, Melo van Lent D, Zheng Y, Ascherio A, Willett W, Yuan C. Association of the Mediterranean dietary approaches to stop hypertension intervention for neurodegenerative delay (MIND) diet with the risk of dementia. JAMA Psychiat. 2023;80:630\u20138. https:\/\/doi.org\/10.1001\/jamapsychiatry.2023.0800.","journal-title":"JAMA Psychiat"},{"key":"1488_CR165","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12937-024-01036-x","volume":"23","author":"Z Ying","year":"2024","unstructured":"Ying Z, Fu M, Fang Z, Ye X, Wang P, Lu J. Mediterranean diet lowers risk of new-onset diabetes: a nationwide cohort study in China. Nutr J. 2024;23:131. https:\/\/doi.org\/10.1186\/s12937-024-01036-x.","journal-title":"Nutr J"},{"key":"1488_CR166","doi-asserted-by":"publisher","first-page":"112121","DOI":"10.1016\/j.exger.2023.112121","volume":"174","author":"LJ Dominguez","year":"2023","unstructured":"Dominguez LJ, Veronese N, Di Bella G, Cusumano C, Parisi A, Tagliaferri F, Ciriminna S, Barbagallo M. Mediterranean diet in the management and prevention of obesity. Exp Gerontol. 2023;174:112121. https:\/\/doi.org\/10.1016\/j.exger.2023.112121.","journal-title":"Exp Gerontol"},{"key":"1488_CR167","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1038\/s41581-021-00430-6","volume":"17","author":"Z Ungvari","year":"2021","unstructured":"Ungvari Z, Toth P, Tarantini S, Prodan CI, Sorond F, Merkely B, Csiszar A. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 2021;17:639\u201354. https:\/\/doi.org\/10.1038\/s41581-021-00430-6.","journal-title":"Nat Rev Nephrol"},{"key":"1488_CR168","doi-asserted-by":"publisher","unstructured":"Legrand R, Nuemi G, Poulain M, Manckoundia P. Description of lifestyle, including social life, diet and physical activity, of people \u226590 years living in Ikaria, a longevity blue zone. Int J Environ Res Public Health. 2021;18. https:\/\/doi.org\/10.3390\/ijerph18126602.","DOI":"10.3390\/ijerph18126602"},{"key":"1488_CR169","unstructured":"Eurostat. Estimates of dementia prevalence rate per 100 000 among older adults (\u226560 years) in the EU in 2019. https:\/\/knowledge4policy.ec.europa.eu\/health-promotion-knowledge-gateway\/dementia-prevalence-3_en. Accessed on 10\/31\/2024."},{"key":"1488_CR170","doi-asserted-by":"publisher","unstructured":"\u201cGlobal Burden of Disease Stroke Risk Factor Collaborators:\u201d global, regional, and national burden of stroke and its risk factors, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Neurol. 2024;23:973\u20131003. https:\/\/doi.org\/10.1016\/S1474-4422(24)00369-7.","DOI":"10.1016\/S1474-4422(24)00369-7"},{"key":"1488_CR171","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1016\/S1474-4422(24)00363-6","volume":"23","author":"S Wu","year":"2024","unstructured":"Wu S, Liu M. Global burden of stroke: dynamic estimates to inform action. Lancet Neurol. 2024;23:952\u20133. https:\/\/doi.org\/10.1016\/S1474-4422(24)00363-6.","journal-title":"Lancet Neurol"},{"key":"1488_CR172","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1186\/s12889-024-19337-5","volume":"24","author":"X Chen","year":"2024","unstructured":"Chen X, Zheng J, Wang J, Wang H, Shi H, Jiang H, Shan P, Liu Q. Global burden and cross-country inequalities in stroke and subtypes attributable to diet from 1990 to 2019. BMC Public Health. 2024;24:1813. https:\/\/doi.org\/10.1186\/s12889-024-19337-5.","journal-title":"BMC Public Health"},{"key":"1488_CR173","unstructured":"Eurostat. Cardiovascular diseases statistics. https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Cardiovascular_diseases_statistics#Deaths_from_cardiovascular_diseases . Accessed 10\/31\/2024."},{"key":"1488_CR174","doi-asserted-by":"publisher","unstructured":"Sarkadi Nagy E, Bakacs M, Illes E, Nagy B, Varga A, Kis O, Schreiberne Molnar E, Martos E. [Hungarian diet and nutritional status survey - OTAP2014. II. Energy and macronutrient intake of the Hungarian population]. Orv Hetil. 2017;158:587\u2013597. https:\/\/doi.org\/10.1556\/650.2017.30718.","DOI":"10.1556\/650.2017.30718"},{"key":"1488_CR175","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s11357-023-01018-7","volume":"46","author":"Z Ungvari","year":"2024","unstructured":"Ungvari Z, Tabak AG, Adany R, Purebl G, Kaposvari C, Fazekas-Pongor V, Csipo T, Szarvas Z, Horvath K, Mukli P, Balog P, Bodizs R, Ujma P, Stauder A, Belsky DW, Kovacs I, Yabluchanskiy A, Maier AB, Moizs M, Ostlin P, Yon Y, Varga P, Voko Z, Papp M, Takacs I, Vasarhelyi B, Torzsa P, Ferdinandy P, Csiszar A, Benyo Z, et al. The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging. Geroscience. 2024;46:191\u2013218. https:\/\/doi.org\/10.1007\/s11357-023-01018-7.","journal-title":"Geroscience"},{"key":"1488_CR176","unstructured":"G\u00f6rgey A. \u00dcber die festen, fl\u00fcchtigen, fetten S\u00e4ueren des Cocusnuss\u00f6les. In: Sitzungsberichte der mathematisch-naturwissenschaftlichen Classe der k. Akademie der Wissenschaften in Wien. Vienna: Akademie der Wissenschaften in Wien. 1848:208\u2014227."}],"container-title":["GeroScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-024-01488-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11357-024-01488-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-024-01488-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T09:03:24Z","timestamp":1750496604000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11357-024-01488-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,11]]},"references-count":176,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["1488"],"URL":"https:\/\/doi.org\/10.1007\/s11357-024-01488-3","relation":{},"ISSN":["2509-2723"],"issn-type":[{"value":"2509-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,11]]},"assertion":[{"value":"22 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health, the American Heart Association, or the Presbyterian Health Foundation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Dr. Bal\u00e1zs Gy\u0151rffy serves as Associate Editor for GeroScience. Dr. Zoltan Ungvari serves as Editor-in-Chief for GeroScience and has personal relationships with individuals involved in the submission of this paper.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}