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While controlled studies suggest that enhancing indoor lighting may alleviate the negative effects of reduced light sensitivity, evidence for this to be effective in the real world is lacking. This study investigates the effects of two light conditions on actigraphic rest-activity rhythms and subjective sleep in healthy older adults (\u2265\u200960\u00a0years) living at home. Two photon-matched lights were compared; a control white light (4000\u00a0K) and a blue-enriched white light (17000\u00a0K) at two different intensities (300\u2013450\u00a0lx and 1100\u20131200\u00a0lx respectively). Participants (<jats:italic>n<\/jats:italic>\u2009=\u200936, 25 female) completed an 11-week randomized, cross-over study, comprising 1\u00a0week of baseline, 3\u00a0weeks of self-administered light exposure (2\u00a0h in the morning and 2\u00a0h in the evening), and 2\u00a0weeks of washout for each light condition. Participants completed sleep diaries, wore a wrist actigraph and a light sensor necklace, and collected urine to measure 6-sulphatoxymelatonin. Longer duration of morning blue-enriched light significantly improved rest-activity rhythm stability and decreased sleep fragmentation. More time spent above 2500\u00a0lx increased actigraphy amplitude, daytime activity, and advanced bedtime. Evening light exposure, however, increased sleep latency and lowered sleep efficiency. Our findings show morning blue-enriched light is beneficial whereas evening light should be avoided. Optimal timing of self-administered light interventions thus may offer a promising strategy to improve sleep and rest-activity rhythms in older adults in real-world settings.<\/jats:p>","DOI":"10.1007\/s11357-025-01506-y","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T01:58:29Z","timestamp":1737079109000},"page":"3927-3939","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The bright and dark side of blue-enriched light on sleep and activity in older adults"],"prefix":"10.1007","volume":"47","author":[{"given":"D\u00e9bora","family":"Barroggi Constantino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina A.","family":"Lederle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benita","family":"Middleton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Revell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey L.","family":"Sletten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra J.","family":"Skene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8037-1407","authenticated-orcid":false,"given":"Daan R.","family":"van der Veen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"issue":"1","key":"1506_CR1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.neuron.2017.02.004","volume":"94","author":"BA Mander","year":"2017","unstructured":"Mander BA, Winer JR, Walker MP. 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