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Transcranial direct current stimulation (tDCS) has shown promise as a cognitive enhancement tool for both healthy aging and age- related cognitive disorders. However, its effectiveness in enhancing word-finding ability remains inconsistent, especially among healthy adults. Variability across studies is likely due to factors such as task selection, stimulation parameters, and small and variable sample sizes. Additionally, many studies have overlooked within-study variability of potentially relevant participant characteristics, including the role of baseline performance in evaluating tDCS efficacy. In this preregistered study, we examined 72 older and 72 younger adults using a double-blind, sham-controlled design, delivering anodal focal tDCS to either the left inferior frontal gyrus or the left temporoparietal junction. Baseline naming performance and fluid intelligence were measured before stimulation. Anodal stimulation of the left inferior frontal gyrus significantly increased response speed for object and action naming in older adults, but crucially only in older adults who performed poorly during the baseline naming session,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.02, \u03b7\n                    <jats:sup>2<\/jats:sup>\n                    \u209a\u2009=\u20090.17. Findings demonstrate regionally specific effects of focal tDCS in healthy older individuals in greater need for naming facilitation. Notably, performance on a broad measure of fluid intelligence was unrelated to stimulation response, suggesting task specificity of this effect.\n                  <\/jats:p>","DOI":"10.1007\/s11357-025-01674-x","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T07:08:05Z","timestamp":1746860885000},"page":"6839-6849","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Regionally specific picture naming benefits of focal tDCS are dependent on baseline performance in older adults"],"prefix":"10.1007","volume":"47","author":[{"given":"A.","family":"Yucel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Niemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Meinzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9445-9151","authenticated-orcid":false,"given":"A. 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